TreeWAS – Variant ID: rs116911364

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000	0.000
I60-I69 Cerebrovascular diseases	0.999	0.001	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.999	0.001	0.000
R07 Pain in throat and chest	0.998	0.002	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.998	0.002	0.000
R07.4 Chest pain, unspecified	0.996	0.004	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.996	0.004	0.000
Chapter XXI Factors influencing health status and contact with health services	0.995	0.005	0.000
Chapter I Certain infectious and parasitic diseases	0.992	0.008	0.000
I63 Cerebral infarction	0.990	0.010	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.986	0.014	0.000
I63.9 Cerebral infarction, unspecified	0.976	0.024	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.969	0.031	0.000
Z50 Care involving use of rehabilitation procedures	0.969	0.031	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.968	0.032	0.000
Chapter VI Diseases of the nervous system	0.966	0.034	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.966	0.034	0.000
C78.0 Secondary malignant neoplasm of lung	0.963	0.037	0.000
Chapter VII Diseases of the eye and adnexa	0.962	0.038	0.000
B95-B98 Bacterial, viral and other infectious agents	0.958	0.042	0.000
Chapter VIII Diseases of the ear and mastoid process	0.955	0.045	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.954	0.046	0.000
R50-R69 General symptoms and signs	0.942	0.058	0.000
Chapter V Mental and behavioural disorders	0.942	0.058	0.000
I67 Other cerebrovascular diseases	0.938	0.062	0.000
H40-H42 Glaucoma	0.938	0.062	0.000
D00-D09 In situ neoplasms	0.938	0.062	0.000
M45-M49 Spondylopathies	0.937	0.063	0.000
M50-M54 Other dorsopathies	0.934	0.066	0.000
Z50.1 Other physical therapy	0.934	0.066	0.000
Chapter X Diseases of the respiratory system	0.929	0.071	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.926	0.074	0.000
I20-I25 Ischaemic heart diseases	0.923	0.077	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.923	0.077	0.000
R51 Headache	0.923	0.077	0.000
H40 Glaucoma	0.921	0.079	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.919	0.081	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.916	0.084	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.914	0.086	0.000
R07.0 Pain in throat	0.912	0.088	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.908	0.092	0.000
C15-C26 Malignant neoplasms of digestive organs	0.907	0.093	0.000
G90-G99 Other disorders of the nervous system	0.906	0.094	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.903	0.097	0.000
C51-C58 Malignant neoplasms of female genital organs	0.903	0.097	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.899	0.101	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.894	0.106	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.893	0.107	0.000
M47 Spondylosis	0.892	0.108	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.887	0.113	0.000
Chapter XXII Codes for special purposes	0.886	0.114	0.000
R06 Abnormalities of breathing	0.879	0.121	0.000
E00-E07 Disorders of thyroid gland	0.878	0.122	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.878	0.122	0.000
H90-H95 Other disorders of ear	0.878	0.122	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.875	0.125	0.000
J90-J94 Other diseases of pleura	0.875	0.125	0.000
F41 Other anxiety disorders	0.872	0.128	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.870	0.130	0.000
D06 Carcinoma in situ of cervix uteri	0.870	0.130	0.000
M54 Dorsalgia	0.866	0.134	0.000
E10-E14 Diabetes mellitus	0.861	0.139	0.000
R09.1 Pleurisy	0.859	0.141	0.000
C78.7 Secondary malignant neoplasm of liver	0.859	0.141	0.000
A30-A49 Other bacterial diseases	0.858	0.142	0.000
S20-S29 Injuries to the thorax	0.853	0.147	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.849	0.151	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.846	0.154	0.000
H40.1 Primary open-angle glaucoma	0.846	0.154	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.845	0.155	0.000
C25 Malignant neoplasm of pancreas	0.843	0.157	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.841	0.159	0.000
R55 Syncope and collapse	0.840	0.160	0.000
M65-M68 Disorders of synovium and tendon	0.837	0.163	0.000
R42 Dizziness and giddiness	0.837	0.163	0.000
I69 Sequelae of cerebrovascular disease	0.834	0.166	0.000
I84 Haemorrhoids	0.833	0.167	0.000
G91 Hydrocephalus	0.832	0.168	0.000
I20 Angina pectoris	0.832	0.168	0.000
Chapter XX External causes of morbidity and mortality	0.831	0.169	0.000
H65-H75 Diseases of middle ear and mastoid	0.831	0.169	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.826	0.174	0.000
B25-B34 Other viral diseases	0.826	0.174	0.000
Z43 Attention to artificial openings	0.825	0.175	0.000
R52 Pain, not elsewhere classified	0.824	0.176	0.000
M47.8 Other spondylosis	0.823	0.177	0.000
I84.2 Internal haemorrhoids without complication	0.823	0.177	0.000
Z50.5 Speech therapy	0.822	0.178	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.821	0.179	0.000
D06.9 Cervix, unspecified	0.821	0.179	0.000
I63.8 Other cerebral infarction	0.820	0.180	0.000
E20-E35 Disorders of other endocrine glands	0.820	0.180	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.818	0.181	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.814	0.186	0.000
Z80 Family history of malignant neoplasm	0.811	0.189	0.000
M51 Other intervertebral disk disorders	0.809	0.191	0.000
I24 Other acute ischaemic heart diseases	0.807	0.193	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.807	0.193	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.807	0.193	0.000
M05-M14 Inflammatory polyarthropathies	0.803	0.197	0.000
I67.9 Cerebrovascular disease, unspecified	0.803	0.197	0.000
H40.9 Glaucoma, unspecified	0.801	0.199	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.801	0.199	0.000
H40.0 Glaucoma suspect	0.800	0.200	0.000
Z45 Adjustment and management of implanted device	0.797	0.203	0.000
R45 Symptoms and signs involving emotional state	0.797	0.203	0.000
Z30 Contraceptive management	0.797	0.203	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.797	0.203	0.000
C78.2 Secondary malignant neoplasm of pleura	0.796	0.204	0.000
Z86 Personal history of certain other diseases	0.796	0.204	0.000
I61 Intracerebral haemorrhage	0.796	0.204	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.795	0.205	0.000
H91 Other hearing loss	0.794	0.206	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.793	0.207	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.790	0.210	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.788	0.212	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.787	0.213	0.000
Z36 Antenatal screening	0.787	0.213	0.000
C92 Myeloid leukaemia	0.786	0.214	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.784	0.216	0.000
I05-I09 Chronic rheumatic heart diseases	0.783	0.217	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.783	0.217	0.000
J90 Pleural effusion, not elsewhere classified	0.783	0.217	0.000
I67.2 Cerebral atherosclerosis	0.782	0.218	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.782	0.218	0.000
I74 Arterial embolism and thrombosis	0.781	0.219	0.000
Z52 Donors of organs and tissues	0.781	0.219	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.781	0.219	0.000
I20.1 Angina pectoris with documented spasm	0.780	0.220	0.000
M47.82 Other spondylosis (Cervical region)	0.780	0.220	0.000
I21 Acute myocardial infarction	0.779	0.221	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.778	0.222	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.778	0.222	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.777	0.223	0.000
J20-J22 Other acute lower respiratory infections	0.774	0.226	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.773	0.227	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.772	0.228	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.770	0.230	0.000
O60-O75 Complications of labour and delivery	0.770	0.230	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.769	0.231	0.000
R06.5 Mouth breathing	0.768	0.232	0.000
A41 Other septicaemia	0.767	0.233	0.000
R07.3 Other chest pain	0.767	0.233	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.765	0.235	0.000
T81 Complications of procedures, not elsewhere classified	0.764	0.236	0.000
M54.5 Low back pain	0.764	0.236	0.000
Z50.2 Alcohol rehabilitation	0.764	0.236	0.000
C80 Malignant neoplasm without specification of site	0.763	0.237	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.762	0.238	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.762	0.238	0.000
S80-S89 Injuries to the knee and lower leg	0.762	0.238	0.000
E07 Other disorders of thyroid	0.761	0.239	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.761	0.239	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.761	0.239	0.000
I84.8 Unspecified haemorrhoids with other complications	0.759	0.241	0.000
C56 Malignant neoplasm of ovary	0.759	0.241	0.000
G91.9 Hydrocephalus, unspecified	0.754	0.246	0.000
A80-A89 Viral infections of the central nervous system	0.753	0.247	0.000
C79 Secondary malignant neoplasm of other sites	0.751	0.249	0.000
I77 Other disorders of arteries and arterioles	0.750	0.250	0.000
I67.1 Cerebral aneurysm, nonruptured	0.750	0.250	0.000
C54 Malignant neoplasm of corpus uteri	0.750	0.250	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.749	0.250	0.000
F41.9 Anxiety disorder, unspecified	0.749	0.251	0.000
C25.9 Pancreas, unspecified	0.749	0.251	0.000
I71 Aortic aneurysm and dissection	0.748	0.252	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.746	0.254	0.000
D03 Melanoma in situ	0.746	0.254	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.744	0.256	0.000
E10 Insulin-dependent diabetes mellitus	0.743	0.257	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.741	0.259	0.000
S00-S09 Injuries to the head	0.741	0.259	0.000
R06.4 Hyperventilation	0.741	0.259	0.000
J92 Pleural plaque	0.740	0.260	0.000
E03 Other hypothyroidism	0.740	0.260	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.739	0.261	0.000
Z50.8 Care involving use of rehabilitation procedures	0.739	0.261	0.000
M46 Other inflammatory spondylopathies	0.739	0.261	0.000
C16 Malignant neoplasm of stomach	0.738	0.262	0.000
R53 Malaise and fatigue	0.738	0.262	0.000
M65 Synovitis and tenosynovitis	0.736	0.264	0.000
H10-H13 Disorders of conjunctiva	0.736	0.264	0.000
M47.9 Spondylosis, unspecified	0.736	0.264	0.000
I60 Subarachnoid haemorrhage	0.735	0.264	0.000
E65-E68 Obesity and other hyperalimentation	0.735	0.265	0.000
S40-S49 Injuries to the shoulder and upper arm	0.735	0.265	0.000
C17 Malignant neoplasm of small intestine	0.734	0.266	0.000
I67.8 Other specified cerebrovascular diseases	0.734	0.266	0.000
H91.9 Hearing loss, unspecified	0.734	0.266	0.000
Z35 Supervision of high-risk pregnancy	0.732	0.268	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.729	0.271	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.728	0.272	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.728	0.272	0.000
Z54 Convalescence	0.727	0.273	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.727	0.273	0.000
E11 Non-insulin-dependent diabetes mellitus	0.727	0.273	0.000
Z86.7 Personal history of diseases of the circulatory system	0.727	0.273	0.000
M45 Ankylosing spondylitis	0.726	0.274	0.000
C25.0 Head of pancreas	0.726	0.274	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.726	0.274	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.726	0.274	0.000
H55-H59 Other disorders of eye and adnexa	0.726	0.274	0.000
M91-M94 Chondropathies	0.724	0.276	0.000
G93 Other disorders of brain	0.723	0.277	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.722	0.278	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.722	0.278	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.721	0.279	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.721	0.279	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.720	0.280	0.000
A41.9 Septicaemia, unspecified	0.719	0.281	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.718	0.282	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.716	0.283	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.716	0.283	0.000
I62 Other nontraumatic intracranial haemorrhage	0.716	0.283	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.716	0.284	0.000
R07.1 Chest pain on breathing	0.716	0.284	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.715	0.284	0.000
I21.9 Acute myocardial infarction, unspecified	0.715	0.285	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.715	0.285	0.000
J00-J06 Acute upper respiratory infections	0.715	0.285	0.000
H40.2 Primary angle-closure glaucoma	0.715	0.285	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.714	0.286	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.714	0.286	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.714	0.286	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.714	0.286	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.714	0.286	0.000
Z86.0 Personal history of other neoplasms	0.714	0.286	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.714	0.286	0.000
B15-B19 Viral hepatitis	0.713	0.286	0.000
R50 Fever of unknown origin	0.713	0.287	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.713	0.287	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.712	0.287	0.000
M40-M43 Deforming dorsopathies	0.712	0.288	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.712	0.288	0.000
B99-B99 Other infectious diseases	0.711	0.289	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.711	0.289	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.711	0.289	0.000
B65-B83 Helminthiases	0.711	0.289	0.000
B50-B64 Protozoal diseases	0.711	0.289	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.711	0.289	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.711	0.289	0.000
A75-A79 Rickettsioses	0.711	0.289	0.000
A70-A74 Other diseases caused by chlamydiae	0.711	0.289	0.000
A65-A69 Other spirochaetal diseases	0.711	0.289	0.000
A20-A28 Certain zoonotic bacterial diseases	0.711	0.289	0.000
A15-A19 Tuberculosis	0.711	0.289	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.711	0.289	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.710	0.290	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.710	0.290	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.710	0.290	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.710	0.290	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.710	0.290	0.000
J91 Pleural effusion in conditions classified elsewhere	0.709	0.291	0.000
R57 Shock, not elsewhere classified	0.708	0.292	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.707	0.293	0.000
M60-M63 Disorders of muscles	0.707	0.293	0.000
M00-M03 Infectious arthropathies	0.707	0.293	0.000
B34 Viral infection of unspecified site	0.707	0.293	0.000
H80-H83 Diseases of inner ear	0.705	0.295	0.000
M86-M90 Other osteopathies	0.705	0.295	0.000
F41.2 Mixed anxiety and depressive disorder	0.705	0.295	0.000
M47.2 Other spondylosis with radiculopathy	0.704	0.296	0.000
C64-C68 Malignant neoplasms of urinary tract	0.704	0.296	0.000
T66-T78 Other and unspecified effects of external causes	0.704	0.296	0.000
B35-B49 Mycoses	0.702	0.297	0.000
M54.2 Cervicalgia	0.701	0.298	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.701	0.298	0.000
F43 Reaction to severe stress, and adjustment disorders	0.701	0.299	0.000
Z40 Prophylactic surgery	0.700	0.300	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.699	0.301	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.698	0.302	0.000
B07 Viral warts	0.696	0.304	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.696	0.304	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.695	0.305	0.000
C53 Malignant neoplasm of cervix uteri	0.695	0.305	0.000
Z72 Problems related to lifestyle	0.695	0.305	0.000
Z49 Care involving dialysis	0.695	0.305	0.000
Z44 Fitting and adjustment of external prosthetic device	0.695	0.305	0.000
Z50.6 Orthoptic training	0.694	0.305	0.000
Z50.3 Drug rehabilitation	0.694	0.305	0.000
T33-T35 Frostbite	0.694	0.306	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.694	0.306	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.694	0.306	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.694	0.306	0.000
T00-T07 Injuries involving multiple body regions	0.694	0.306	0.000
S10-S19 Injuries to the neck	0.694	0.306	0.000
J09-J18 Influenza and pneumonia	0.694	0.306	0.000
G96 Other disorders of central nervous system	0.693	0.306	0.000
G70-G73 Diseases of myoneural junction and muscle	0.693	0.307	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.693	0.307	0.000
F30-F39 Mood [affective] disorders	0.692	0.308	0.000
H93 Other disorders of ear, not elsewhere classified	0.692	0.308	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.692	0.308	0.000
R52.2 Other chronic pain	0.691	0.309	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.690	0.310	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.690	0.310	0.000
T79-T79 Certain early complications of trauma	0.690	0.310	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.688	0.312	0.000
Z86.6 Personal history of diseases of the nervous system and sense organs	0.687	0.313	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.686	0.314	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.686	0.314	0.000
O70 Perineal laceration during delivery	0.685	0.314	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.684	0.316	0.000
E40-E46 Malnutrition	0.684	0.316	0.000
H60-H62 Diseases of external ear	0.683	0.317	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.683	0.317	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.683	0.317	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.683	0.317	0.000
H25-H28 Disorders of lens	0.682	0.318	0.000
H43-H45 Disorders of vitreous body and globe	0.682	0.318	0.000
R26 Abnormalities of gait and mobility	0.682	0.318	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.682	0.318	0.000
G30-G32 Other degenerative diseases of the nervous system	0.681	0.319	0.000
Chapter XI Diseases of the digestive system	0.680	0.320	0.000
G35 Multiple sclerosis	0.679	0.320	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.679	0.321	0.000
M06 Other rheumatoid arthritis	0.679	0.321	0.000
E07.9 Disorder of thyroid, unspecified	0.678	0.322	0.000
Z43.2 Attention to ileostomy	0.677	0.323	0.000
R56 Convulsions, not elsewhere classified	0.677	0.323	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.676	0.324	0.000
H65 Nonsuppurative otitis media	0.676	0.324	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.675	0.325	0.000
R62 Lack of expected normal physiological development	0.675	0.325	0.000
R64 Cachexia	0.675	0.325	0.000
R58 Haemorrhage, not elsewhere classified	0.675	0.325	0.000
F99-F99 Unspecified mental disorder	0.675	0.325	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.675	0.325	0.000
F80-F89 Disorders of psychological development	0.675	0.325	0.000
F70-F79 Mental retardation	0.675	0.325	0.000
F60-F69 Disorders of adult personality and behaviour	0.675	0.325	0.000
S22.0 Fracture of thoracic vertebra	0.675	0.325	0.000
B00 Herpesviral [herpes simplex] infections	0.675	0.325	0.000
G91.1 Obstructive hydrocephalus	0.674	0.325	0.000
S90-S99 Injuries to the ankle and foot	0.674	0.326	0.000
U80 Agent resistant to penicillin and related antibiotics	0.674	0.326	0.000
C92.1 Chronic myeloid leukaemia	0.674	0.326	0.000
R09.0 Asphyxia	0.674	0.326	0.000
I73 Other peripheral vascular diseases	0.674	0.326	0.000
M80-M85 Disorders of bone density and structure	0.674	0.326	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.673	0.327	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.673	0.327	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.673	0.327	0.000
I67.5 Moyamoya disease	0.673	0.327	0.000
I67.4 Hypertensive encephalopathy	0.673	0.327	0.000
I67.3 Progressive vascular leukoencephalopathy	0.673	0.327	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.673	0.327	0.000
I84.4 External haemorrhoids with other complications	0.673	0.327	0.000
H42 Glaucoma in diseases classified elsewhere	0.672	0.327	0.000
I85 Oesophageal varices	0.673	0.327	0.000
D09 Carcinoma in situ of other and unspecified sites	0.672	0.327	0.000
D04 Carcinoma in situ of skin	0.672	0.327	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.672	0.327	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.672	0.327	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.672	0.327	0.000
M49 Spondylopathies in diseases classified elsewhere	0.672	0.328	0.000
H73 Other disorders of tympanic membrane	0.671	0.329	0.000
Z97 Presence of other devices	0.671	0.329	0.000
M54.1 Radiculopathy	0.671	0.329	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.671	0.329	0.000
H53-H54 Visual disturbances and blindness	0.671	0.329	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.671	0.329	0.000
Z37 Outcome of delivery	0.670	0.330	0.000
M53 Other dorsopathies, not elsewhere classified	0.670	0.330	0.000
Z50.0 Cardiac rehabilitation	0.669	0.331	0.000
R06.2 Wheezing	0.669	0.331	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.668	0.331	0.000
S20 Superficial injury of thorax	0.668	0.332	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.667	0.333	0.000
T86 Failure and rejection of transplanted organs and tissues	0.667	0.333	0.000
G57 Mononeuropathies of lower limb	0.667	0.333	0.000
M05 Seropositive rheumatoid arthritis	0.666	0.333	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.666	0.334	0.000
M54.6 Pain in thoracic spine	0.664	0.336	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.664	0.336	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.664	0.336	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.664	0.336	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.664	0.336	0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.664	0.336	0.000
R07.2 Precordial pain	0.663	0.337	0.000
J22 Unspecified acute lower respiratory infection	0.662	0.338	0.000
Z45.8 Adjustment and management of other implanted devices	0.662	0.338	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.662	0.338	0.000
I23 Certain current complications following acute myocardial infarction	0.662	0.338	0.000
C91 Lymphoid leukaemia	0.662	0.338	0.000
R46 Symptoms and signs involving appearance and behaviour	0.662	0.338	0.000
R43 Disturbances of smell and taste	0.662	0.338	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.662	0.338	0.000
Z96 Presence of other functional implants	0.661	0.339	0.000
I20.0 Unstable angina	0.661	0.339	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.661	0.339	0.000
D37.4 Colon	0.661	0.339	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.660	0.339	0.000
H04 Disorders of lachrymal system	0.661	0.339	0.000
R02 Gangrene, not elsewhere classified	0.660	0.339	0.000
H90 Conductive and sensorineural hearing loss	0.660	0.340	0.000
H40.8 Other glaucoma	0.660	0.340	0.000
H40.6 Glaucoma secondary to drugs	0.660	0.340	0.000
H40.5 Glaucoma secondary to other eye disorders	0.660	0.340	0.000
H40.4 Glaucoma secondary to eye inflammation	0.660	0.340	0.000
H40.3 Glaucoma secondary to eye trauma	0.660	0.340	0.000
R45.2 Unhappiness	0.659	0.340	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.659	0.341	0.000
R09.3 Abnormal sputum	0.659	0.341	0.000
R09.2 Respiratory arrest	0.659	0.341	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.659	0.341	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.659	0.341	0.000
O70.0 First degree perineal laceration during delivery	0.659	0.341	0.000
D05 Carcinoma in situ of breast	0.658	0.342	0.000
R29.6 Tendency to fall, not elsewhere classified	0.658	0.342	0.000
M20-M25 Other joint disorders	0.658	0.342	0.000
R47-R49 Symptoms and signs involving speech and voice	0.657	0.343	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.657	0.343	0.000
I72 Other aneurysm	0.657	0.343	0.000
G51 Facial nerve disorders	0.656	0.344	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.656	0.344	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.656	0.344	0.000
Z38 Liveborn infants according to place of birth	0.655	0.345	0.000
Z32 Pregnancy examination and test	0.655	0.345	0.000
Z31 Procreative management	0.655	0.345	0.000
M65.3 Trigger finger	0.655	0.345	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.654	0.346	0.000
T93 Sequelae of injuries of lower limb	0.653	0.347	0.000
Z39 Postpartum care and examination	0.651	0.349	0.000
E06 Thyroiditis	0.650	0.350	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.650	0.350	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.650	0.350	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.650	0.350	0.000
C21 Malignant neoplasm of anus and anal canal	0.650	0.350	0.000
C23 Malignant neoplasm of gallbladder	0.650	0.350	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.650	0.350	0.000
S70-S79 Injuries to the hip and thigh	0.650	0.350	0.000
I78 Diseases of capillaries	0.650	0.350	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.650	0.350	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.649	0.350	0.000
E50-E64 Other nutritional deficiencies	0.649	0.350	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.649	0.350	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.649	0.351	0.000
G95 Other diseases of spinal cord	0.649	0.351	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.649	0.351	0.000
G90 Disorders of autonomic nervous system	0.649	0.351	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.649	0.351	0.000
G92 Toxic encephalopathy	0.649	0.351	0.000
C15 Malignant neoplasm of oesophagus	0.648	0.352	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.648	0.352	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.648	0.352	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.648	0.352	0.000
R52.9 Pain, unspecified	0.647	0.352	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.647	0.353	0.000
C51 Malignant neoplasm of vulva	0.647	0.353	0.000
C58 Malignant neoplasm of placenta	0.647	0.353	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.647	0.353	0.000
C52 Malignant neoplasm of vagina	0.647	0.353	0.000
E11.9 Without complications	0.647	0.353	0.000
Z52.4 Kidney donor	0.646	0.354	0.000
M51.2 Other specified intervertebral disk displacement	0.646	0.354	0.000
R05 Cough	0.645	0.355	0.000
E23 Hypofunction and other disorders of pituitary gland	0.645	0.355	0.000
F48 Other neurotic disorders	0.644	0.355	0.000
F44 Dissociative [conversion] disorders	0.644	0.355	0.000
F42 Obsessive-compulsive disorder	0.644	0.355	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.644	0.356	0.000
Z30.2 Sterilisation	0.643	0.357	0.000
J92.9 Pleural plaque without asbestos	0.643	0.357	0.000
R68 Other general symptoms and signs	0.641	0.358	0.000
E10.9 Without complications	0.642	0.358	0.000
E03.9 Hypothyroidism, unspecified	0.641	0.359	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.640	0.359	0.000
C95 Leukaemia of unspecified cell type	0.640	0.359	0.000
C94 Other leukaemias of specified cell type	0.640	0.359	0.000
C93 Monocytic leukaemia	0.640	0.359	0.000
C88 Malignant immunoproliferative diseases	0.640	0.359	0.000
C86 Other specified types of T/NK-cell lymphoma	0.640	0.359	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.640	0.359	0.000
C81 Hodgkin's disease	0.640	0.359	0.000
F01 Vascular dementia	0.640	0.360	0.000
C54.1 Endometrium	0.640	0.360	0.000
M47.1 Other spondylosis with myelopathy	0.640	0.360	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.640	0.360	0.000
Z34 Supervision of normal pregnancy	0.640	0.360	0.000
D45 Polycythaemia vera	0.640	0.360	0.000
G20-G26 Extrapyramidal and movement disorders	0.638	0.362	0.000
R79 Other abnormal findings of blood chemistry	0.638	0.362	0.000
E28 Ovarian dysfunction	0.637	0.362	0.000
M54.56 Low back pain (Lumbar region)	0.637	0.363	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.636	0.364	0.000
T87 Complications peculiar to reattachment and amputation	0.636	0.364	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.636	0.364	0.000
M70-M79 Other soft tissue disorders	0.634	0.365	0.001
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.635	0.365	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.635	0.365	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations