TreeWAS – Variant ID: rs11694327

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
I10-I15 Hypertensive diseases	0.409	0.591	0.000
I12 Hypertensive renal disease	0.310	0.690	0.000
I13 Hypertensive heart and renal disease	0.293	0.707	0.000
I11 Hypertensive heart disease	0.289	0.710	0.000
I15 Secondary hypertension	0.273	0.727	0.000
I12.0 Hypertensive renal disease with renal failure	0.253	0.747	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.214	0.786	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.210	0.790	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.210	0.790	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.210	0.790	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.210	0.790	0.000
I15.0 Renovascular hypertension	0.208	0.792	0.000
I12.9 Hypertensive renal disease without renal failure	0.201	0.799	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.197	0.803	0.000
I15.8 Other secondary hypertension	0.196	0.804	0.000
I15.2 Hypertension secondary to endocrine disorders	0.196	0.804	0.000
I15.9 Seconday hypertension, unspecified	0.187	0.813	0.000
I15.1 Hypertension secondary to other renal disorders	0.168	0.832	0.000
N18.3 Chronic kidney disease, stage 3	0.032	0.968	0.000
N18 Chronic renal failure	0.029	0.971	0.000
N18.4 Chronic kidney disease, stage 4	0.025	0.975	0.000
N18.5 Chronic kidney disease, stage 5	0.025	0.975	0.000
N19 Unspecified renal failure	0.025	0.975	0.000
N18.9 Chronic renal failure, unspecified	0.024	0.976	0.000
N17-N19 Renal failure	0.024	0.976	0.000
N18.8 Other chronic renal failure	0.022	0.978	0.000
N18.1 Chronic kidney disease, stage 1	0.020	0.980	0.000
N18.0 End-stage renal disease	0.018	0.982	0.000
N17 Acute renal failure	0.015	0.985	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.986	0.014
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.013	0.987	0.000
N17.2 Acute renal failure with medullary necrosis	0.011	0.989	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.011	0.989	0.000
N17.8 Other acute renal failure	0.011	0.989	0.000
N17.9 Acute renal failure, unspecified	0.011	0.989	0.000
N18.2 Chronic kidney disease, stage 2	0.010	0.990	0.000
C43 Malignant melanoma of skin	0.000	0.990	0.010
N17.0 Acute renal failure with tubular necrosis	0.010	0.990	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.990	0.010
C43.9 Malignant melanoma of skin, unspecified	0.000	0.991	0.009
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.009	0.991	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.992	0.008
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.992	0.008
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.008	0.992	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.007	0.993	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.993	0.007
C43.0 Malignant melanoma of lip	0.000	0.993	0.007
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.993	0.007
C43.5 Malignant melanoma of trunk	0.000	0.993	0.007
O21.0 Mild hyperemesis gravidarum	0.007	0.993	0.000
Z49.1 Extracorporeal dialysis	0.007	0.993	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.993	0.007
G91 Hydrocephalus	0.000	0.993	0.007
Z49.0 Preparatory care for dialysis	0.007	0.993	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.006	0.993	0.000
O21 Excessive vomiting in pregnancy	0.006	0.994	0.000
O23.5 Infections of the genital tract in pregnancy	0.006	0.994	0.000
O23 Infections of genito-urinary tract in pregnancy	0.006	0.994	0.000
Z49 Care involving dialysis	0.006	0.994	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.006	0.994	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.994	0.006
F52.2 Failure of genital response	0.000	0.994	0.006
S12 Fracture of neck	0.006	0.994	0.000
G91.0 Communicating hydrocephalus	0.000	0.994	0.006
S12.1 Fracture of second cervical vertebra	0.006	0.994	0.000
Z49.2 Other dialysis	0.006	0.994	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.006	0.994	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.006	0.994	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.006	0.994	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.006	0.994	0.000
U80.0 Penicillin resistant agent	0.006	0.994	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.006	0.994	0.000
K86.2 Cyst of pancreas	0.000	0.994	0.006
O23.4 Unspecified infection of urinary tract in pregnancy	0.006	0.994	0.000
N30.3 Trigonitis	0.000	0.994	0.006
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.005	0.995	0.000
O26.9 Pregnancy-related condition, unspecified	0.005	0.995	0.000
O26.8 Other specified pregnancy-related conditions	0.005	0.995	0.000
O21.2 Late vomiting of pregnancy	0.005	0.995	0.000
S12.0 Fracture of first cervical vertebra	0.005	0.995	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.005	0.995	0.000
G91.8 Other hydrocephalus	0.000	0.995	0.005
S10.9 Superficial injury of neck, part unspecified	0.005	0.995	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.995	0.005
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.005	0.995	0.000
D37.5 Rectum	0.000	0.995	0.005
S10 Superficial injury of neck	0.005	0.995	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.995	0.005
G90 Disorders of autonomic nervous system	0.000	0.995	0.005
S12.00 Fracture of first cervical vertebra (closed)	0.005	0.995	0.000
S12.2 Fracture of other specified cervical vertebra	0.005	0.995	0.000
O22 Venous complications in pregnancy	0.005	0.995	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.005	0.995	0.000
S10-S19 Injuries to the neck	0.005	0.995	0.000
D37.7 Other digestive organs	0.000	0.995	0.005
G90-G99 Other disorders of the nervous system	0.000	0.995	0.005
O23.3 Infections of other parts of urinary tract in pregnancy	0.005	0.995	0.000
O23.2 Infections of urethra in pregnancy	0.005	0.995	0.000
O23.1 Infections of bladder in pregnancy	0.005	0.995	0.000
O23.0 Infections of kidney in pregnancy	0.005	0.995	0.000
K86 Other diseases of pancreas	0.000	0.995	0.005
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.005	0.995	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.995	0.005
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.995	0.005
O21.8 Other vomiting complicating pregnancy	0.004	0.995	0.000
G91.2 Normal-pressure hydrocephalus	0.000	0.995	0.004
O21.9 Vomiting of pregnancy, unspecified	0.004	0.995	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.995	0.005
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.995	0.005
O26.0 Excessive weight gain in pregnancy	0.004	0.995	0.000
S12.8 Fracture of other parts of neck	0.004	0.996	0.000
G93 Other disorders of brain	0.000	0.996	0.004
S12.11 Fracture of second cervical vertebra (open)	0.004	0.996	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.004	0.996	0.000
D37.0 Lip, oral cavity and pharynx	0.000	0.996	0.004
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.996	0.004
N92.1 Excessive and frequent menstruation with irregular cycle	0.000	0.996	0.004
S10.8 Superficial injury of other parts of neck	0.004	0.996	0.000
S12.7 Multiple fractures of cervical spine	0.004	0.996	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O26.5 Maternal hypotension syndrome	0.004	0.996	0.000
O26.4 Herpes gestationis	0.004	0.996	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.004	0.996	0.000
O26.1 Low weight gain in pregnancy	0.004	0.996	0.000
S12.9 Fracture of neck, part unspecified	0.004	0.996	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.004	0.996	0.000
O29 Complications of anaesthesia during pregnancy	0.004	0.996	0.000
O25 Malnutrition in pregnancy	0.004	0.996	0.000
G93.3 Postviral fatigue syndrome	0.000	0.996	0.004
S11 Open wound of neck	0.004	0.996	0.000
G91.1 Obstructive hydrocephalus	0.000	0.996	0.004
F40.2 Specific (isolated) phobias	0.000	0.996	0.004
S12.01 Fracture of first cervical vertebra (open)	0.004	0.996	0.000
G93.5 Compression of brain	0.000	0.996	0.004
G93.2 Benign intracranial hypertension	0.000	0.996	0.004
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.996	0.004
S19 Other and unspecified injuries of neck	0.004	0.996	0.000
S10.7 Multiple superficial injuries of neck	0.004	0.996	0.000
S10.1 Other and unspecified superficial injuries of throat	0.004	0.996	0.000
S10.0 Contusion of throat	0.004	0.996	0.000
G90.8 Other disorders of autonomic nervous system	0.000	0.996	0.004
G90.4 Autonomic dysreflexia	0.000	0.996	0.004
G90.1 Familial dysautonomia [Riley-Day]	0.000	0.996	0.004
G93.9 Disorder of brain, unspecified	0.000	0.996	0.004
K86.1 Other chronic pancreatitis	0.000	0.996	0.004
S11.7 Multiple open wounds of neck	0.004	0.996	0.000
O22.4 Haemorrhoids in pregnancy	0.004	0.996	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.004	0.996	0.000
D37.1 Stomach	0.000	0.996	0.004
O22.0 Varicose veins of lower extremity in pregnancy	0.004	0.996	0.000
O22.9 Venous complication in pregnancy, unspecified	0.004	0.996	0.000
O22.8 Other venous complications in pregnancy	0.004	0.996	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.004	0.996	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.004	0.996	0.000
O22.1 Genital varices in pregnancy	0.004	0.996	0.000
G90.3 Multisystem degeneration	0.000	0.996	0.004
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.996	0.004
O24 Diabetes mellitus in pregnancy	0.004	0.996	0.000
S17 Crushing injury of neck	0.004	0.996	0.000
S15 Injury of blood vessels at neck level	0.004	0.996	0.000
S18 Traumatic amputation at neck level	0.004	0.996	0.000
S16 Injury of muscle and tendon at neck level	0.004	0.996	0.000
D37.3 Appendix	0.000	0.996	0.004
G92 Toxic encephalopathy	0.000	0.996	0.004
O62.2 Other uterine inertia	0.004	0.996	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.004	0.996	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.996	0.004
D37.4 Colon	0.000	0.996	0.004
S11.9 Open wound of neck, part unspecified	0.003	0.996	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.004	0.996	0.000
O28 Abnormal findings on antenatal screening of mother	0.003	0.996	0.000
S14 Injury of nerves and spinal cord at neck level	0.003	0.996	0.000
S12.81 Fracture of other parts of neck (open)	0.003	0.997	0.000
S12.80 Fracture of other parts of neck (closed)	0.003	0.997	0.000
G93.7 Reye's syndrome	0.000	0.997	0.003
H73.8 Other specified disorders of tympanic membrane	0.000	0.997	0.003
S12.71 Multiple fractures of cervical spine (open)	0.003	0.997	0.000
K86.3 Pseudocyst of pancreas	0.000	0.997	0.003
O26.2 Pregnancy care of habitual aborter	0.003	0.997	0.000
O20 Haemorrhage in early pregnancy	0.003	0.997	0.000
S12.91 Fracture of neck, part unspecified (open)	0.003	0.997	0.000
G95.1 Vascular myelopathies	0.000	0.997	0.003
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.003	0.997	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.003	0.997	0.000
O29.6 Failed or difficult intubation during pregnancy	0.003	0.997	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.003	0.997	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.003	0.997	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.003	0.997	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.003	0.997	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.003	0.997	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.003	0.997	0.000
H18.2 Other corneal oedema	0.003	0.997	0.000
O62.3 Precipitate labour	0.003	0.997	0.000
S11.8 Open wound of other parts of neck	0.003	0.997	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.003	0.997	0.000
S11.1 Open wound involving thyroid gland	0.003	0.997	0.000
S11.0 Open wound involving larynx and trachea	0.003	0.997	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.003	0.997	0.000
G82.5 Tetraplegia, unspecified	0.000	0.997	0.003
S12.90 Fracture of neck, part unspecified (closed)	0.003	0.997	0.000
D37.2 Small intestine	0.000	0.997	0.003
G93.4 Encephalopathy, unspecified	0.000	0.997	0.003
K86.8 Other specified diseases of pancreas	0.000	0.997	0.003
S19.9 Unspecified injury of neck	0.003	0.997	0.000
D37.9 Digestive organ, unspecified	0.000	0.997	0.003
D37.6 Liver, gallbladder and bile ducts	0.000	0.997	0.003
U80 Agent resistant to penicillin and related antibiotics	0.003	0.997	0.000
G94.1 Hydrocephalus in neoplastic disease	0.000	0.997	0.003
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.997	0.003
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.997	0.003
S19.8 Other specified injuries of neck	0.003	0.997	0.000
G96 Other disorders of central nervous system	0.000	0.997	0.003
G82.2 Paraplegia, unspecified	0.000	0.997	0.003
M21.1 Varus deformity, not elsewhere classified	0.003	0.997	0.000
S19.7 Multiple injuries of neck	0.003	0.997	0.000
G93.0 Cerebral cysts	0.000	0.997	0.003
G90.2 Horner's syndrome	0.000	0.997	0.003
G82 Paraplegia and tetraplegia	0.000	0.997	0.003
O20.0 Threatened abortion	0.003	0.997	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.997	0.003
G95 Other diseases of spinal cord	0.000	0.997	0.003
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.997	0.003
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.997	0.003
O24.3 Pre-existing diabetes mellitus, unspecified	0.003	0.997	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.003	0.997	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.003	0.997	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.003	0.997	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.003	0.997	0.000
S15.8 Injury of other blood vessels at neck level	0.003	0.997	0.000
S15.7 Injury of multiple blood vessels at neck level	0.003	0.997	0.000
S15.3 Injury of internal jugular vein	0.003	0.997	0.000
S15.2 Injury of external jugular vein	0.003	0.997	0.000
S15.1 Injury of vertebral artery	0.003	0.997	0.000
S15.0 Injury of carotid artery	0.003	0.997	0.000
S17.9 Crushing injury of neck, part unspecified	0.003	0.997	0.000
S17.8 Crushing injury of other parts of neck	0.003	0.997	0.000
S17.0 Crushing injury of larynx and traches	0.003	0.997	0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.000	0.997	0.003
G82.4 Spastic tetraplegia	0.000	0.997	0.003
M23.8 Other internal derangements of knee	0.003	0.997	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.003	0.997	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.000	0.997	0.003
H18 Other disorders of cornea	0.003	0.997	0.000
O62 Abnormalities of forces of labour	0.003	0.997	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.000	0.997	0.003
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
S13.5 Sprain and strain of thyroid region	0.003	0.997	0.000
S13.3 Multiple dislocations of neck	0.003	0.997	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.003	0.997	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.003	0.997	0.000
E10.1 With ketoacidosis	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
K04.7 Periapical abscess without sinus	0.000	0.997	0.003
G97.8 Other postprocedural disorders of nervous system	0.000	0.997	0.003
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.997	0.003
S13.1 Dislocation of cervical vertebra	0.003	0.997	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.997	0.003
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.003	0.997	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.003	0.997	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.003	0.997	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.003	0.997	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.003	0.997	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.003	0.997	0.000
G82.1 Spastic paraplegia	0.000	0.997	0.003
M50.1 Cervical disk disorder with radiculopathy	0.003	0.997	0.000
S14.6 Injury of other and unspecified nerves of neck	0.003	0.997	0.000
S14.5 Injury of cervical sympathetic nerves	0.003	0.997	0.000
S14.4 Injury of peripheral nerves of neck	0.003	0.997	0.000
S14.2 Injury of nerve root of cervical spine	0.003	0.997	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.003	0.997	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.003	0.997	0.000
H18.4 Corneal degeneration	0.003	0.997	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.003	0.997	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
S13.4 Sprain and strain of cervical spine	0.003	0.997	0.000
S14.3 Injury of brachial plexus	0.003	0.997	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.002	0.997	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.997	0.003
N85.4 Malposition of uterus	0.003	0.997	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
G96.9 Disorder of central nervous system, unspecified	0.000	0.997	0.002
O00.1 Tubal pregnancy	0.000	0.997	0.003
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.002	0.997	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.997	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.002	0.997	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.002	0.997	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.002	0.997	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.002	0.997	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.002	0.997	0.000
M96.5 Postradiation scoliosis	0.002	0.997	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.997	0.000
G96.8 Other specified disorders of central nervous system	0.000	0.997	0.002
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.997	0.000
G82.3 Flaccid tetraplegia	0.000	0.997	0.002
G82.0 Flaccid paraplegia	0.000	0.997	0.002
G93.6 Cerebral oedema	0.000	0.997	0.002
G94.2 Hydrocephalus in other diseases classified elsewhere	0.000	0.997	0.002
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.997	0.002
K04.5 Chronic apical periodontitis	0.000	0.998	0.002
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.002	0.998	0.000
R21 Rash and other nonspecific skin eruption	0.002	0.998	0.000
I35.1 Aortic (valve) insufficiency	0.002	0.998	0.000
O62.1 Secondary uterine inertia	0.002	0.998	0.000
V89.9 Person injured in unspecified vehicle accident	0.000	0.998	0.002
M23.87 Other internal derangements of knee (Capsular ligament)	0.002	0.998	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
R47.0 Dysphasia and aphasia	0.000	0.998	0.002
V89.3 Person injured in unspecified nonmotor-vehicle accident, traffic	0.000	0.998	0.002
V89.1 Person injured in unspecified nonmotor-vehicle accident, nontraffic	0.000	0.998	0.002
V89.0 Person injured in unspecified motor-vehicle accident, nontraffic	0.000	0.998	0.002
Z32.0 Pregnancy, not (yet) confirmed	0.002	0.998	0.000
H18.7 Other corneal deformities	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
O62.9 Abnormality of forces of labour, unspecified	0.002	0.998	0.000
O62.8 Other abnormalities of forces of labour	0.002	0.998	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.002	0.998	0.000
D07.5 Prostate	0.000	0.998	0.002
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.7 Excessive sexual drive	0.000	0.998	0.002
F52.6 Nonorganic dyspareunia	0.000	0.998	0.002
F52.5 Nonorganic vaginismus	0.000	0.998	0.002
F52.4 Premature ejaculation	0.000	0.998	0.002
F52.3 Orgasmic dysfunction	0.000	0.998	0.002
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.002	0.998	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.002	0.998	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
Z32.1 Pregnancy confirmed	0.002	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.998	0.002
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.002	0.998	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.002	0.998	0.000
M96.4 Postsurgical lordosis	0.002	0.998	0.000
M96.3 Postlaminectomy kyphosis	0.002	0.998	0.000
M96.2 Postradiation kyphosis	0.002	0.998	0.000
Z48.0 Attention to surgical dressings and sutures	0.002	0.998	0.000
O02.1 Missed abortion	0.002	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.002	0.998	0.000
F52.0 Lack or loss of sexual desire	0.000	0.998	0.002
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
O62.0 Primary inadequate contractions	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
Z91.6 Personal history of other physical trauma	0.002	0.998	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.002	0.998	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.998	0.002
H18.1 Bullous keratopathy	0.002	0.998	0.000
M95.2 Other acquired deformity of head	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.002	0.998	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.000	0.998	0.002
G93.8 Other specified disorders of brain	0.000	0.998	0.002
Z11.0 Special screening examination for intestinal infectious diseases	0.002	0.998	0.000
G95.0 Syringomyelia and syringobulbia	0.000	0.998	0.002
G95.8 Other specified diseases of spinal cord	0.000	0.998	0.002
K75.4 Autoimmune hepatitis	0.000	0.998	0.002
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.998	0.002
M95.3 Acquired deformity of neck	0.002	0.998	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.002	0.998	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.002	0.998	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.998	0.002
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
S37.0 Injury of kidney	0.002	0.998	0.000
F40 Phobic anxiety disorders	0.000	0.998	0.002
M95.0 Acquired deformity of nose	0.002	0.998	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
Z32 Pregnancy examination and test	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.002	0.998	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.002	0.998	0.000
M95.5 Acquired deformity of pelvis	0.002	0.998	0.000
M95.1 Cauliflower ear	0.002	0.998	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
M99 Biomechanical lesions, not elsewhere classified	0.002	0.998	0.000
T25 Burn and corrosion of ankle and foot	0.002	0.998	0.000
M95.4 Acquired deformity of chest and rib	0.002	0.998	0.000
N49.2 Inflammatory disorders of scrotum	0.002	0.998	0.000
T25.2 Burn of second degree of ankle and foot	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.998	0.002
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.998	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.998	0.002
N32.8 Other specified disorders of bladder	0.002	0.998	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.998	0.002
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
R26.3 Immobility	0.002	0.998	0.000
S37 Injury of urinary and pelvic organs	0.002	0.998	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.998	0.002
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.998	0.002
T25.0 Burn of unspecified degree of ankle and foot	0.002	0.998	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.002	0.998	0.000
S37.01 Injury of kidney (with open wound into cavity)	0.001	0.998	0.000
F40.9 Phobic anxiety disorder, unspecified	0.000	0.998	0.001
F40.8 Other phobic anxiety disorders	0.000	0.998	0.001
F40.1 Social phobias	0.000	0.998	0.001
M99.5 Intervertebral disk stenosis of neural canal	0.001	0.998	0.000
G44.2 Tension-type headache	0.002	0.998	0.000
Z45.1 Adjustment and management of infusion pump	0.000	0.998	0.002
Z32.9 Pregnancy confirmed (erroneous code. See Z321)	0.001	0.998	0.000
U50 Level of care administered to neonates	0.001	0.998	0.000
U07 Emergency use of U07	0.001	0.998	0.000
U06 Emergency use of U06	0.001	0.998	0.000
U04 Severe acute respiratory syndrome [SARS]	0.001	0.998	0.000
U52 First in a series of a regular day/night admissions	0.001	0.998	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.001	0.998	0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.000	0.998	0.001
T23 Burn and corrosion of wrist and hand	0.002	0.998	0.000
M99.50 Intervertebral disc stenosis of neural canal (Head region)	0.001	0.998	0.000
E10.4 With neurological complications	0.002	0.998	0.000
M99.9 Biomechanical lesion, unspecified	0.001	0.998	0.000
M99.8 Other biomechanical lesions	0.001	0.998	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.001	0.998	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.998	0.000
M99.4 Connective tissue stenosis of neural canal	0.001	0.998	0.000
M99.3 Osseous stenosis of neural canal	0.001	0.998	0.000
M99.2 Subluxation stenosis of neural canal	0.001	0.998	0.000
M99.1 Subluxation complex (vertebral)	0.001	0.998	0.000
M99.0 Segmental and somatic dysfunction	0.001	0.998	0.000
T25.7 Corrosion of third degree of ankle and foot	0.001	0.998	0.000
T25.6 Corrosion of second degree of ankle and foot	0.001	0.998	0.000
T25.5 Corrosion of first degree of ankle and foot	0.001	0.998	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.001	0.998	0.000
T25.3 Burn of third degree of ankle and foot	0.001	0.998	0.000
T25.1 Burn of first degree of ankle and foot	0.001	0.998	0.000
T21 Burn and corrosion of trunk	0.001	0.998	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.001	0.998	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.998	0.002
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
T23.2 Burn of second degree of wrist and hand	0.001	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.001	0.999	0.000
S37.9 Injury of unspecified pelvic organ	0.001	0.999	0.000
S37.8 Injury of other pelvic organs	0.001	0.999	0.000
S37.7 Injury of multiple pelvic organs	0.001	0.999	0.000
S37.6 Injury of uterus	0.001	0.999	0.000
S37.5 Injury of Fallopian tube	0.001	0.999	0.000
S37.4 Injury of ovary	0.001	0.999	0.000
S37.3 Injury of urethra	0.001	0.999	0.000
S37.2 Injury of bladder	0.001	0.999	0.000
S37.1 Injury of ureter	0.001	0.999	0.000
T21.1 Burn of first degree of trunk	0.001	0.999	0.000
U81.0 Vancomycin resistant agent	0.001	0.999	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.999	0.001
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
K04 Diseases of pulp and periapical tissues	0.000	0.999	0.001
T20 Burn and corrosion of head and neck	0.001	0.999	0.000
M99.59 Intervertebral disc stenosis of neural canal-Abdomen/other	0.001	0.999	0.000
M99.58 Intervertebral disc stenosis of neural canal-Rib cage	0.001	0.999	0.000
M99.57 Intervertebral disc stenosis of neural canal-Upper extremit	0.001	0.999	0.000
M99.56 Intervertebral disc stenosis of neural canal-Lower extremit	0.001	0.999	0.000
M99.55 Intervertebral disc stenosis of neural canal (Pelvic region)	0.001	0.999	0.000
M99.54 Intervertebral disc stenosis of neural canal (Sacral region)	0.001	0.999	0.000
M99.53 Intervertebral disc stenosis of neural canal (Lumbar region)	0.001	0.999	0.000
M99.52 Intervertebral disc stenosis of neural canal (Thoracic region)	0.001	0.999	0.000
M99.51 Intervertebral disc stenosis of neural canal (Cervical region)	0.001	0.999	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.001	0.999	0.000
Z11.1 Special screening examination for respiratory tuberculosis	0.001	0.999	0.000
F40.0 Agoraphobia	0.000	0.999	0.001
I44.0 Atrioventricular block, first degree	0.001	0.999	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.999	0.001
K29.3 Chronic superficial gastritis	0.001	0.999	0.000
Z11.5 Special screening examination for other viral diseases	0.001	0.999	0.000
S92.10 Fracture of talus (closed)	0.001	0.999	0.000
E10.2 With renal complications	0.001	0.999	0.000
E16.2 Hypoglycaemia, unspecified	0.001	0.999	0.000
K04.6 Periapical abscess with sinus	0.000	0.999	0.001
T20.2 Burn of second degree of head and neck	0.001	0.999	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.001	0.999	0.000
U06.9 Emergency use of U06.9	0.001	0.999	0.000
U06.8 Emergency use of U06.8	0.001	0.999	0.000
U06.7 Emergency use of U06.7	0.001	0.999	0.000
U06.6 Emergency use of U06.6	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations