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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116962450
log Bayes Factor = 7.81708
Chromosome 12   position 90,500,741  (GRCh37) Explore rs116962450 on Ensembl!
Variant rs116962450 is part of Cluster X0188

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
S40-S49 Injuries to the shoulder and upper arm
0.992 0.008 0.000
G20-G26 Extrapyramidal and movement disorders
0.989 0.011 0.000
I51 Complications and ill-defined descriptions of heart disease
0.989 0.011 0.000
M45-M49 Spondylopathies
0.986 0.014 0.000
S20-S29 Injuries to the thorax
0.981 0.019 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.978 0.022 0.000
I34 Nonrheumatic mitral valve disorders
0.975 0.025 0.000
I60-I69 Cerebrovascular diseases
0.975 0.025 0.000
I51.7 Cardiomegaly
0.970 0.030 0.000
G20 Parkinson's disease
0.965 0.035 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.965 0.035 0.000
M20-M25 Other joint disorders
0.962 0.038 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.960 0.040 0.000
M50-M54 Other dorsopathies
0.958 0.042 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.957 0.043 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.956 0.044 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.952 0.048 0.000
M48 Other spondylopathies
0.951 0.049 0.000
M54 Dorsalgia
0.951 0.049 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.942 0.058 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.939 0.061 0.000
M54.9 Dorsalgia, unspecified
0.936 0.064 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.930 0.070 0.000
M48.0 Spinal stenosis
0.930 0.070 0.000
I34.1 Mitral (valve) prolapse
0.928 0.072 0.000
I35 Nonrheumatic aortic valve disorders
0.926 0.074 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.920 0.080 0.000
C34 Malignant neoplasm of bronchus and lung
0.920 0.080 0.000
Chapter VIII Diseases of the ear and mastoid process
0.913 0.087 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.908 0.092 0.000
S22.4 Multiple fractures of ribs
0.907 0.093 0.000
S43.0 Dislocation of shoulder joint
0.907 0.093 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.904 0.096 0.000
M48.06 Spinal stenosis (Lumbar region)
0.903 0.097 0.000
C15-C26 Malignant neoplasms of digestive organs
0.902 0.098 0.000
I51.9 Heart disease, unspecified
0.896 0.104 0.000
C91 Lymphoid leukaemia
0.894 0.106 0.000
I05-I09 Chronic rheumatic heart diseases
0.893 0.107 0.000
M23 Internal derangement of knee
0.893 0.107 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.892 0.108 0.000
D48.1 Connective and other soft tissue
0.884 0.116 0.000
I34.0 Mitral (valve) insufficiency
0.882 0.118 0.000
S80-S89 Injuries to the knee and lower leg
0.880 0.120 0.000
I35.0 Aortic (valve) stenosis
0.879 0.121 0.000
M47 Spondylosis
0.877 0.123 0.000
S22.40 Multiple fractures of ribs (closed)
0.875 0.125 0.000
I45 Other conduction disorders
0.873 0.127 0.000
T79-T79 Certain early complications of trauma
0.872 0.128 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.872 0.128 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.872 0.128 0.000
C79 Secondary malignant neoplasm of other sites
0.869 0.131 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.867 0.133 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.864 0.136 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.863 0.137 0.000
S27 Injury of other and unspecified intrathoracic organs
0.859 0.141 0.000
S50-S59 Injuries to the elbow and forearm
0.859 0.141 0.000
G40-G47 Episodic and paroxysmal disorders
0.856 0.144 0.000
M23.8 Other internal derangements of knee
0.852 0.148 0.000
H90-H95 Other disorders of ear
0.851 0.149 0.000
D48.7 Other specified sites
0.851 0.149 0.000
M22 Disorders of patella
0.849 0.151 0.000
S00-S09 Injuries to the head
0.847 0.153 0.000
S10-S19 Injuries to the neck
0.846 0.154 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.846 0.154 0.000
M25 Other joint disorders, not elsewhere classified
0.844 0.156 0.000
C88 Malignant immunoproliferative diseases
0.844 0.156 0.000
G70-G73 Diseases of myoneural junction and muscle
0.843 0.157 0.000
S42 Fracture of shoulder and upper arm
0.843 0.157 0.000
I31 Other diseases of pericardium
0.841 0.159 0.000
M54.1 Radiculopathy
0.839 0.161 0.000
G24 Dystonia
0.839 0.161 0.000
I36 Nonrheumatic tricuspid valve disorders
0.838 0.162 0.000
C34.9 Bronchus or lung, unspecified
0.836 0.164 0.000
M47.9 Spondylosis, unspecified
0.836 0.164 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.833 0.167 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.832 0.168 0.000
G25 Other extrapyramidal and movement disorders
0.830 0.170 0.000
G40 Epilepsy
0.830 0.170 0.000
C45 Mesothelioma
0.827 0.173 0.000
C34.1 Upper lobe, bronchus or lung
0.826 0.174 0.000
M86-M90 Other osteopathies
0.824 0.176 0.000
I30 Acute pericarditis
0.823 0.177 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.820 0.180 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.820 0.180 0.000
G56 Mononeuropathies of upper limb
0.819 0.181 0.000
S40 Superficial injury of shoulder and upper arm
0.818 0.182 0.000
I08 Multiple valve diseases
0.818 0.182 0.000
M91-M94 Chondropathies
0.817 0.183 0.000
M24 Other specific joint derangements
0.815 0.185 0.000
H65-H75 Diseases of middle ear and mastoid
0.813 0.187 0.000
C80 Malignant neoplasm without specification of site
0.812 0.188 0.000
S70-S79 Injuries to the hip and thigh
0.809 0.191 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.806 0.194 0.000
M46 Other inflammatory spondylopathies
0.804 0.196 0.000
G40.9 Epilepsy, unspecified
0.803 0.197 0.000
M80-M85 Disorders of bone density and structure
0.798 0.202 0.000
M25.5 Pain in joint
0.796 0.204 0.000
C91.1 Chronic lymphocytic leukaemia
0.796 0.204 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.796 0.204 0.000
M22.2 Patellofemoral disorders
0.794 0.206 0.000
M70-M79 Other soft tissue disorders
0.794 0.206 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.792 0.208 0.000
S80 Superficial injury of lower leg
0.790 0.210 0.000
M60-M63 Disorders of muscles
0.789 0.211 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.788 0.212 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.788 0.212 0.000
M54.4 Lumbago with sciatica
0.788 0.212 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.786 0.214 0.000
I51.0 Cardiac septal defect, acquired
0.783 0.217 0.000
G50 Disorders of trigeminal nerve
0.783 0.217 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.781 0.219 0.000
G56.0 Carpal tunnel syndrome
0.780 0.220 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.779 0.221 0.000
I67 Other cerebrovascular diseases
0.777 0.223 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.777 0.223 0.000
S22.0 Fracture of thoracic vertebra
0.776 0.223 0.000
G30-G32 Other degenerative diseases of the nervous system
0.775 0.225 0.000
C18 Malignant neoplasm of colon
0.774 0.226 0.000
Chapter XXI Factors influencing health status and contact with health services
0.774 0.226 0.000
H93 Other disorders of ear, not elsewhere classified
0.773 0.227 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.772 0.228 0.000
C15 Malignant neoplasm of oesophagus
0.771 0.229 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.770 0.230 0.000
H90 Conductive and sensorineural hearing loss
0.769 0.231 0.000
G90-G99 Other disorders of the nervous system
0.768 0.232 0.000
Z72.0 Tobacco use
0.768 0.232 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.767 0.232 0.000
M54.16 Radiculopathy (Lumbar region)
0.765 0.235 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.765 0.235 0.000
S52 Fracture of forearm
0.765 0.235 0.000
Z72 Problems related to lifestyle
0.764 0.236 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.764 0.236 0.000
S80.9 Superficial injury of lower leg, unspecified
0.763 0.237 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.756 0.244 0.000
C95 Leukaemia of unspecified cell type
0.754 0.245 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.754 0.246 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.753 0.246 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.753 0.247 0.000
I26 Pulmonary embolism
0.752 0.248 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.751 0.249 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.751 0.249 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.750 0.250 0.000
T92 Sequelae of injuries of upper limb
0.749 0.251 0.000
C17 Malignant neoplasm of small intestine
0.748 0.251 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.748 0.252 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.747 0.253 0.000
I45.1 Other and unspecified right bundle-branch block
0.747 0.253 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.745 0.255 0.000
M49 Spondylopathies in diseases classified elsewhere
0.744 0.255 0.000
I45.3 Trifascicular block
0.744 0.256 0.000
T00-T07 Injuries involving multiple body regions
0.743 0.257 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.743 0.257 0.000
M25.51 Pain in joint (Shoulder region)
0.741 0.259 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.741 0.259 0.000
Q21 Congenital malformations of cardiac septa
0.741 0.259 0.000
I47 Paroxysmal tachycardia
0.739 0.261 0.000
S05 Injury of eye and orbit
0.739 0.261 0.000
M23.3 Other meniscus derangements
0.739 0.261 0.000
C45.9 Mesothelioma, unspecified
0.738 0.262 0.000
S41 Open wound of shoulder and upper arm
0.737 0.263 0.000
S06 Intracranial injury
0.737 0.263 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.737 0.263 0.000
M48.09 Spinal stenosis (Site unspecified)
0.737 0.263 0.000
S27.2 Traumatic heamopneumothorax
0.737 0.263 0.000
C91.0 Acute lymphoblastic leukaemia
0.737 0.263 0.000
G54 Nerve root and plexus disorders
0.736 0.264 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.736 0.264 0.000
S22.3 Fracture of rib
0.734 0.266 0.000
I60 Subarachnoid haemorrhage
0.734 0.266 0.000
D48.5 Skin
0.731 0.269 0.000
M31 Other necrotising vasculopathies
0.731 0.269 0.000
I07 Rheumatic tricuspid valve diseases
0.726 0.274 0.000
C81 Hodgkin's disease
0.725 0.275 0.000
T93 Sequelae of injuries of lower limb
0.725 0.275 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.724 0.276 0.000
S42.3 Fracture of shaft of humerus
0.723 0.277 0.000
I31.9 Disease of pericardium, unspecified
0.723 0.277 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.722 0.278 0.000
C32 Malignant neoplasm of larynx
0.721 0.279 0.000
I44 Atrioventricular and left bundle-branch block
0.721 0.279 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.720 0.280 0.000
M75 Shoulder lesions
0.720 0.280 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.720 0.280 0.000
M89 Other disorders of bone
0.720 0.280 0.000
S46.2 Injury of muscle and tendon of other parts of biceps
0.720 0.280 0.000
S81 Open wound of lower leg
0.719 0.281 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.718 0.282 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.283 0.000
I48 Atrial fibrillation and flutter
0.716 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.283 0.000
I40 Acute myocarditis
0.716 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.283 0.000
M54.6 Pain in thoracic spine
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.713 0.287 0.000
S90-S99 Injuries to the ankle and foot
0.712 0.287 0.000
D48.0 Bone and articular cartilage
0.712 0.288 0.000
Q50-Q56 Congenital malformations of genital organs
0.712 0.288 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.712 0.288 0.000
S48 Traumatic amputation of shoulder and upper arm
0.711 0.288 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.711 0.288 0.000
S44 Injury of nerves at shoulder and upper arm level
0.711 0.288 0.000
S47 Crushing injury of shoulder and upper arm
0.711 0.288 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.711 0.289 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.710 0.290 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.710 0.290 0.000
Chapter XXII Codes for special purposes
0.709 0.290 0.000
G23 Other degenerative diseases of basal ganglia
0.709 0.291 0.000
G21 Secondary Parkinsonism
0.709 0.291 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.709 0.291 0.000
G22 Parkinsonism in diseases classified elsewhere
0.709 0.291 0.000
I51.5 Myocardial degeneration
0.709 0.291 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.709 0.291 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.709 0.291 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.709 0.291 0.000
C34.2 Middle lobe, bronchus or lung
0.708 0.292 0.000
I51.4 Myocarditis, unspecified
0.708 0.292 0.000
G82 Paraplegia and tetraplegia
0.708 0.292 0.000
C77.5 Intrapelvic lymph nodes
0.707 0.293 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.704 0.295 0.000
S29 Other and unspecified injuries of thorax
0.703 0.297 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.703 0.297 0.000
S26 Injury of heart
0.703 0.297 0.000
S25 Injury of blood vessels of thorax
0.703 0.297 0.000
S24 Injury of nerves and spinal cord at thorax level
0.703 0.297 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.703 0.297 0.000
S21 Open wound of thorax
0.703 0.297 0.000
I51.6 Cardiovascular disease, unspecified
0.703 0.297 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.701 0.299 0.000
C94 Other leukaemias of specified cell type
0.701 0.299 0.000
C93 Monocytic leukaemia
0.701 0.299 0.000
C86 Other specified types of T/NK-cell lymphoma
0.701 0.299 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.701 0.299 0.000
C77.9 Lymph node, unspecified
0.701 0.299 0.000
G41 Status epilepticus
0.701 0.299 0.000
C18.3 Hepatic flexure
0.700 0.300 0.000
I62 Other nontraumatic intracranial haemorrhage
0.700 0.300 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.700 0.300 0.000
Q28 Other congenital malformations of circulatory system
0.700 0.300 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.699 0.300 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.699 0.301 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.699 0.301 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.699 0.301 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.699 0.301 0.000
S22.5 Flail chest
0.699 0.301 0.000
S52.1 Fracture of upper end of radius
0.697 0.303 0.000
S22.2 Fracture of sternum
0.697 0.303 0.000
Z75 Problems related to medical facilities and other health care
0.697 0.303 0.000
I30.9 Acute pericarditis, unspecified
0.696 0.304 0.000
G25.0 Essential tremor
0.696 0.304 0.000
S02 Fracture of skull and facial bones
0.696 0.304 0.000
G50.0 Trigeminal neuralgia
0.695 0.305 0.000
G80 Infantile cerebral palsy
0.695 0.305 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.695 0.305 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.694 0.305 0.000
S22.1 Multiple fractures of thoracic spine
0.694 0.306 0.000
C34.3 Lower lobe, bronchus or lung
0.693 0.307 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.693 0.307 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.692 0.308 0.000
Q80-Q89 Other congenital malformations
0.691 0.309 0.000
C79.6 Secondary malignant neoplasm of ovary
0.691 0.309 0.000
H66 Suppurative and unspecified otitis media
0.690 0.310 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.689 0.310 0.000
M33 Dermatopolymyositis
0.689 0.310 0.000
M32 Systemic lupus erythematosus
0.689 0.310 0.000
M30 Polyarteritis nodosa and related conditions
0.689 0.310 0.000
H71 Cholesteatoma of middle ear
0.689 0.311 0.000
H90.2 Conductive hearing loss, unspecified
0.688 0.312 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.688 0.312 0.000
I33 Acute and subacute endocarditis
0.687 0.313 0.000
M34 Systemic sclerosis
0.687 0.313 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.687 0.313 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.686 0.314 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.686 0.314 0.000
S19 Other and unspecified injuries of neck
0.686 0.314 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.685 0.315 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.685 0.315 0.000
C31 Malignant neoplasm of accessory sinuses
0.685 0.315 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.685 0.315 0.000
C37 Malignant neoplasm of thymus
0.685 0.315 0.000
C33 Malignant neoplasm of trachea
0.685 0.315 0.000
Q25 Congenital malformations of great arteries
0.685 0.315 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.685 0.315 0.000
H72 Perforation of tympanic membrane
0.684 0.316 0.000
C21 Malignant neoplasm of anus and anal canal
0.683 0.317 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.683 0.317 0.000
S20 Superficial injury of thorax
0.683 0.317 0.000
S22.9 Fracture of bony thorax, part unspecified
0.683 0.317 0.000
S22.8 Fracture of other parts of bony thorax
0.683 0.317 0.000
M48.9 Spondylopathy, unspecified
0.682 0.318 0.000
M48.8 Other specified spondylopathies
0.682 0.318 0.000
M48.4 Fatigue fracture of vertebra
0.682 0.318 0.000
M48.3 Traumatic spondylopathy
0.682 0.318 0.000
M48.2 Kissing spine
0.682 0.318 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.682 0.318 0.000
M54.8 Other dorsalgia
0.682 0.318 0.000
M54.0 Panniculitis affecting regions of neck and back
0.682 0.318 0.000
Q27 Other congenital malformations of peripheral vascular system
0.681 0.319 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.681 0.319 0.000
G24.8 Other dystonia
0.681 0.319 0.000
D37.1 Stomach
0.680 0.320 0.000
M54.5 Low back pain
0.679 0.321 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.679 0.321 0.000
I37 Pulmonary valve disorders
0.678 0.321 0.000
M24.0 Loose body in joint
0.678 0.322 0.000
C78.2 Secondary malignant neoplasm of pleura
0.677 0.323 0.000
M53 Other dorsopathies, not elsewhere classified
0.677 0.323 0.000
S56 Injury of muscle and tendon at forearm level
0.676 0.324 0.000
S32 Fracture of lumbar spine and pelvis
0.676 0.324 0.000
H93.1 Tinnitus
0.676 0.324 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.675 0.325 0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle
0.675 0.325 0.000
S43.6 Sprain and strain of sternoclavicular joint
0.675 0.325 0.000
S43.5 Sprain and strain of acromioclavicular joint
0.675 0.325 0.000
S43.4 Sprain and strain of shoulder joint
0.675 0.325 0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle
0.675 0.325 0.000
S43.2 Dislocation of sternoclavicular joint
0.675 0.325 0.000
S12 Fracture of neck
0.675 0.325 0.000
C77.1 Intrathoracic lymph nodes
0.675 0.325 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.674 0.325 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.674 0.326 0.000
G24.5 Blepharospasm
0.674 0.326 0.000
G72 Other myopathies
0.674 0.326 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.673 0.327 0.000
D48.4 Peritoneum
0.673 0.327 0.000
D48.3 Retroperitoneum
0.673 0.327 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.673 0.327 0.000
G70 Myasthenia gravis and other myoneural disorders
0.673 0.327 0.000
M75.0 Adhesive capsulitis of shoulder
0.673 0.327 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.671 0.329 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.671 0.329 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.671 0.329 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.671 0.329 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.671 0.329 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.671 0.329 0.000
S27.1 Traumatic haemothorax
0.670 0.330 0.000
M25.56 Pain in joint (Lower leg)
0.670 0.330 0.000
Q23 Congenital malformations of aortic and mitral valves
0.669 0.330 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.669 0.331 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.669 0.331 0.000
T91 Sequelae of injuries of neck and trunk
0.667 0.333 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.667 0.333 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.667 0.333 0.000
Q35-Q37 Cleft lip and cleft palate
0.667 0.333 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.667 0.333 0.000
M24.2 Disorder of ligament
0.667 0.333 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.666 0.333 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.666 0.333 0.000
M48.04 Spinal stenosis (Thoracic region)
0.666 0.333 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.666 0.333 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.666 0.333 0.000
M90 Osteopathies in diseases classified elsewhere
0.666 0.334 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.666 0.334 0.000
I27 Other pulmonary heart diseases
0.666 0.334 0.000
I61 Intracerebral haemorrhage
0.665 0.334 0.000
S43.1 Dislocation of acromioclavicular joint
0.664 0.336 0.000
D37.3 Appendix
0.664 0.336 0.000
D48.6 Breast
0.664 0.336 0.000
S70 Superficial injury of hip and thigh
0.663 0.337 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.662 0.338 0.000
C78.7 Secondary malignant neoplasm of liver
0.662 0.338 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.661 0.339 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.660 0.340 0.000
C46 Kaposi's sarcoma
0.660 0.340 0.000
C34.8 Overlapping lesion of bronchus and lung
0.659 0.341 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.658 0.341 0.000
I46 Cardiac arrest
0.658 0.342 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.658 0.342 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.657 0.343 0.000
M54.3 Sciatica
0.655 0.345 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.654 0.346 0.000
M21 Other acquired deformities of limbs
0.654 0.346 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.654 0.346 0.000
G56.1 Other lesions of median nerve
0.653 0.347 0.000
M23.5 Chronic instability of knee
0.652 0.348 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.651 0.349 0.000
S42.4 Fracture of lower end of humerus
0.651 0.349 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.651 0.349 0.000
C79.2 Secondary malignant neoplasm of skin
0.650 0.349 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.650 0.350 0.000
S22.41 Multiple fractures of ribs (open)
0.650 0.350 0.000
I67.9 Cerebrovascular disease, unspecified
0.650 0.350 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.650 0.350 0.000
T23 Burn and corrosion of wrist and hand
0.650 0.350 0.000
M40-M43 Deforming dorsopathies
0.649 0.350 0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)
0.649 0.350 0.000
S52.10 Fracture of upper end of radius (closed)
0.649 0.351 0.000
G81 Hemiplegia
0.649 0.351 0.000
C77.4 Inguinal and lower limb lymph nodes
0.649 0.351 0.000
G51 Facial nerve disorders
0.649 0.351 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.648 0.352 0.000
G52 Disorders of other cranial nerves
0.648 0.352 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.648 0.352 0.000
C23 Malignant neoplasm of gallbladder
0.647 0.353 0.000
Q21.0 Ventricular septal defect
0.646 0.354 0.000
H93.9 Disorder of ear, unspecified
0.646 0.354 0.000
S42.0 Fracture of clavicle
0.645 0.354 0.000
C15.5 Lower third of oesophagus
0.645 0.355 0.000
M84 Disorders of continuity of bone
0.644 0.356 0.000
C18.9 Colon, unspecified
0.644 0.356 0.000
C83.0 Small cell (diffuse)
0.643 0.357 0.000
I45.6 Preexcitation syndrome
0.643 0.357 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.642 0.358 0.000
S42.1 Fracture of scapula
0.642 0.358 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.642 0.358 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.641 0.358 0.000
C91.9 Lymphoid leukaemia, unspecified
0.641 0.359 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.641 0.359 0.000
C91.7 Other lymphoid leukaemia
0.641 0.359 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.641 0.359 0.000
C91.5 Adult T-cell leukaemia
0.641 0.359 0.000
C91.4 Hairy-cell leukaemia
0.641 0.359 0.000
C91.3 Prolymphocytic leukaemia
0.641 0.359 0.000
C91.2 Subacute lymphocytic leukaemia
0.641 0.359 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.641 0.359 0.000
I09 Other rheumatic heart diseases
0.640 0.359 0.000
I06 Rheumatic aortic valve diseases
0.640 0.359 0.000
M23.9 Internal derangement of knee, unspecified
0.640 0.360 0.000
M23.1 Discoid meniscus (congenital)
0.640 0.360 0.000
M23.0 Cystic meniscus
0.640 0.360 0.000
C10 Malignant neoplasm of oropharynx
0.640 0.360 0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level
0.639 0.361 0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level
0.639 0.361 0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level
0.639 0.361 0.000
S46.3 Injury of muscle and tendon of triceps
0.639 0.361 0.000
S46.1 Injury of muscle and tendon of long head of biceps
0.639 0.361 0.000
M62 Other disorders of muscle
0.639 0.361 0.000
C17.9 Small intestine, unspecified
0.639 0.361 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.638 0.362 0.000
S42.30 Fracture of shaft of humerus (closed)
0.638 0.362 0.000
I77 Other disorders of arteries and arterioles
0.637 0.363 0.000
S40.0 Contusion of shoulder and upper arm
0.637 0.363 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.636 0.364 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.636 0.364 0.000
M93 Other osteochondropathies
0.636 0.364 0.000
M25.0 Haemarthrosis
0.636 0.364 0.000
M45 Ankylosing spondylitis
0.635 0.365 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.635 0.365 0.000
I35.9 Aortic valve disorder, unspecified
0.635 0.365 0.000
C83.3 Large cell (diffuse)
0.634 0.366 0.000
I45.8 Other specified conduction disorders
0.633 0.367 0.000
Q24 Other congenital malformations of heart
0.633 0.367 0.000
I71 Aortic aneurysm and dissection
0.632 0.368 0.000
I45.2 Bifascicular block
0.632 0.368 0.000
T98 Sequelae of other and unspecified effects of external causes
0.631 0.369 0.000
S88 Traumatic amputation of lower leg
0.631 0.369 0.000
S87 Crushing injury of lower leg
0.631 0.369 0.000
S85 Injury of blood vessels at lower leg level
0.631 0.369 0.000
S84 Injury of nerves at lower leg level
0.631 0.369 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.631 0.369 0.000
M25.7 Osteophyte
0.631 0.369 0.000
S27.3 Other injuries of lung
0.630 0.370 0.000
I69 Sequelae of cerebrovascular disease
0.629 0.371 0.000
M92 Other juvenile osteochondrosis
0.629 0.371 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.629 0.371 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.628 0.371 0.000
C45.7 Mesothelioma of other sites
0.628 0.372 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.628 0.372 0.000
D37.4 Colon
0.628 0.372 0.000
I45.4 Nonspecific intraventricular block
0.626 0.374 0.000
I45.0 Right fascicular block
0.626 0.374 0.000
I65.2 Occlusion and stenosis of carotid artery
0.626 0.374 0.000
S72 Fracture of femur
0.626 0.374 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.626 0.374 0.000
Z13 Special screening examination for other diseases and disorders
0.626 0.374 0.000
T93.0 Sequelae of open wound of lower limb
0.626 0.374 0.000
D10-D36 Benign neoplasms
0.626 0.374 0.000
T95 Sequelae of burns, corrosions and frostbite
0.625 0.375 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.625 0.375 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.625 0.375 0.000
Q26 Congenital malformations of great veins
0.625 0.375 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.625 0.375 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.625 0.375 0.000
M25.57 Pain in joint (Ankle and foot)
0.624 0.376 0.000
C15.4 Middle third of oesophagus
0.624 0.376 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.624 0.376 0.000
G71 Primary disorders of muscles
0.623 0.377 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.623 0.377 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.623 0.377 0.000
G90 Disorders of autonomic nervous system
0.623 0.377 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.623 0.377 0.000
S27.0 Traumatic pneumothorax
0.623 0.377 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.623 0.377 0.000
S86 Injury of muscle and tendon at lower leg level
0.623 0.377 0.000
T79.6 Traumatic ischaemia of muscle
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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