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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116976641
log Bayes Factor = 23.6656
Chromosome 7   position 18,277,071  (GRCh37) Explore rs116976641 on Ensembl!
Variant rs116976641 is part of Cluster X0106

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
T81 Complications of procedures, not elsewhere classified
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.997 0.003 0.000
M54 Dorsalgia
0.995 0.005 0.000
C79 Secondary malignant neoplasm of other sites
0.995 0.005 0.000
K70-K77 Diseases of liver
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.991 0.009 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.991 0.009 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.986 0.014 0.000
S00-S09 Injuries to the head
0.984 0.016 0.000
Y83.6 Removal of other organ (partial) (total)
0.984 0.016 0.000
M70-M79 Other soft tissue disorders
0.982 0.018 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.980 0.020 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.978 0.022 0.000
M54.5 Low back pain
0.976 0.024 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.973 0.027 0.000
M79.6 Pain in limb
0.973 0.027 0.000
M45-M49 Spondylopathies
0.970 0.030 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.965 0.035 0.000
I95 Hypotension
0.964 0.036 0.000
K55-K64 Other diseases of intestines
0.962 0.038 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.962 0.038 0.000
K76 Other diseases of liver
0.957 0.043 0.000
I95.9 Hypotension, unspecified
0.954 0.046 0.000
I60-I69 Cerebrovascular diseases
0.954 0.046 0.000
I30-I52 Other forms of heart disease
0.954 0.046 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.953 0.047 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.952 0.048 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.951 0.049 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.950 0.050 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.950 0.050 0.000
F10.1 Harmful use
0.946 0.054 0.000
K35-K38 Diseases of appendix
0.943 0.057 0.000
K70 Alcoholic liver disease
0.943 0.057 0.000
M54.56 Low back pain (Lumbar region)
0.940 0.060 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.940 0.060 0.000
K63 Other diseases of intestine
0.936 0.064 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.935 0.065 0.000
M47 Spondylosis
0.933 0.067 0.000
K56.6 Other and unspecified intestinal obstruction
0.929 0.071 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.927 0.073 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.926 0.074 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.923 0.077 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.923 0.077 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.920 0.080 0.000
I47 Paroxysmal tachycardia
0.920 0.080 0.000
V10-V19 Pedal cyclist injured in transport accident
0.919 0.081 0.000
I74 Arterial embolism and thrombosis
0.918 0.082 0.000
K63.5 Polyp of colon
0.917 0.083 0.000
Y83.8 Other surgical procedures
0.917 0.083 0.000
Chapter VIII Diseases of the ear and mastoid process
0.915 0.085 0.000
C34 Malignant neoplasm of bronchus and lung
0.915 0.085 0.000
F10.0 Acute intoxication
0.912 0.088 0.000
Chapter VI Diseases of the nervous system
0.909 0.091 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.907 0.093 0.000
S00 Superficial injury of head
0.905 0.095 0.000
I47.1 Supraventricular tachycardia
0.904 0.096 0.000
S06 Intracranial injury
0.903 0.097 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.898 0.102 0.000
I77 Other disorders of arteries and arterioles
0.896 0.104 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.895 0.105 0.000
Q60-Q64 Congenital malformations of the urinary system
0.895 0.105 0.000
M51 Other intervertebral disk disorders
0.894 0.106 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.893 0.107 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.892 0.108 0.000
I73 Other peripheral vascular diseases
0.889 0.111 0.000
I49 Other cardiac arrhythmias
0.888 0.112 0.000
D70 Agranulocytosis
0.887 0.113 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.884 0.116 0.000
M54.4 Lumbago with sciatica
0.882 0.118 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.882 0.118 0.000
M54.59 Low back pain (Site unspecified)
0.879 0.121 0.000
H90-H95 Other disorders of ear
0.877 0.123 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.871 0.129 0.000
S60-S69 Injuries to the wrist and hand
0.870 0.130 0.000
K35 Acute appendicitis
0.869 0.131 0.000
M79.66 Pain in limb (Lower leg)
0.869 0.131 0.000
Y95 Nosocomial condition
0.868 0.132 0.000
K70.9 Alcoholic liver disease, unspecified
0.865 0.135 0.000
S01 Open wound of head
0.865 0.135 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.865 0.135 0.000
I70 Atherosclerosis
0.864 0.136 0.000
K76.9 Liver disease, unspecified
0.863 0.137 0.000
M47.9 Spondylosis, unspecified
0.861 0.139 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.860 0.140 0.000
C51-C58 Malignant neoplasms of female genital organs
0.856 0.144 0.000
F10.3 Withdrawal state
0.855 0.145 0.000
Q61 Cystic kidney disease
0.852 0.148 0.000
K56.7 Ileus, unspecified
0.851 0.149 0.000
S80-S89 Injuries to the knee and lower leg
0.849 0.151 0.000
W00-W19 Falls
0.848 0.152 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.847 0.153 0.000
C15-C26 Malignant neoplasms of digestive organs
0.841 0.159 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.838 0.162 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.837 0.163 0.000
K72 Hepatic failure, not elsewhere classified
0.836 0.164 0.000
K74 Fibrosis and cirrhosis of liver
0.835 0.165 0.000
M47.8 Other spondylosis
0.835 0.165 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.835 0.165 0.000
S90-S99 Injuries to the ankle and foot
0.834 0.166 0.000
I77.1 Stricture of artery
0.833 0.167 0.000
Chapter X Diseases of the respiratory system
0.832 0.168 0.000
M79.67 Pain in limb (Ankle and foot)
0.832 0.168 0.000
G62 Other polyneuropathies
0.831 0.169 0.000
M54.3 Sciatica
0.829 0.171 0.000
I78 Diseases of capillaries
0.827 0.172 0.000
I46 Cardiac arrest
0.827 0.173 0.000
F17.1 Harmful use
0.827 0.173 0.000
M54.1 Radiculopathy
0.824 0.176 0.000
M51.2 Other specified intervertebral disk displacement
0.823 0.177 0.000
I73.9 Peripheral vascular disease, unspecified
0.820 0.180 0.000
C64-C68 Malignant neoplasms of urinary tract
0.820 0.180 0.000
M47.86 Other spondylosis (Lumbar region)
0.819 0.181 0.000
S20-S29 Injuries to the thorax
0.818 0.182 0.000
K55 Vascular disorders of intestine
0.818 0.182 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.818 0.182 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.817 0.183 0.000
C80 Malignant neoplasm without specification of site
0.815 0.185 0.000
C34.1 Upper lobe, bronchus or lung
0.815 0.185 0.000
Y84.0 Cardiac catheterisation
0.814 0.186 0.000
T66-T78 Other and unspecified effects of external causes
0.814 0.186 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.813 0.186 0.000
I63 Cerebral infarction
0.813 0.187 0.000
I67 Other cerebrovascular diseases
0.811 0.189 0.000
V40-V49 Car occupant injured in transport accident
0.810 0.189 0.000
C77.2 Intra-abdominal lymph nodes
0.810 0.190 0.000
M54.9 Dorsalgia, unspecified
0.808 0.192 0.000
S40-S49 Injuries to the shoulder and upper arm
0.808 0.192 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.807 0.193 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.807 0.193 0.000
H92 Otalgia and effusion of ear
0.806 0.194 0.000
V18.0 Driver injured in nontraffic accident
0.805 0.195 0.000
I62 Other nontraumatic intracranial haemorrhage
0.801 0.199 0.000
G62.9 Polyneuropathy, unspecified
0.800 0.200 0.000
M86-M90 Other osteopathies
0.798 0.202 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.795 0.205 0.000
M77 Other enthesopathies
0.790 0.210 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.790 0.210 0.000
G90-G99 Other disorders of the nervous system
0.790 0.210 0.000
K63.1 Perforation of intestine (nontraumatic)
0.790 0.210 0.000
T91 Sequelae of injuries of neck and trunk
0.789 0.211 0.000
F10.2 Dependence syndrome
0.789 0.211 0.000
S02 Fracture of skull and facial bones
0.789 0.211 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.788 0.212 0.000
M79.2 Neuralgia and neuritis, unspecified
0.787 0.213 0.000
I35 Nonrheumatic aortic valve disorders
0.782 0.218 0.000
T92 Sequelae of injuries of upper limb
0.782 0.218 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.781 0.219 0.000
C77.5 Intrapelvic lymph nodes
0.780 0.219 0.000
S61 Open wound of wrist and hand
0.780 0.220 0.000
M79.8 Other specified soft tissue disorders
0.779 0.221 0.000
C34.9 Bronchus or lung, unspecified
0.778 0.222 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.777 0.223 0.000
H91 Other hearing loss
0.777 0.223 0.000
K76.6 Portal hypertension
0.776 0.224 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.776 0.224 0.000
Y83.0 Surgical operation with transplant of whole organ
0.775 0.225 0.000
T43.2 Other and unspecified antidepressants
0.774 0.226 0.000
K70.4 Alcoholic hepatic failure
0.774 0.226 0.000
I49.3 Ventricular premature depolarisation
0.773 0.227 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.772 0.228 0.000
D60-D64 Aplastic and other anaemias
0.772 0.228 0.000
C79.6 Secondary malignant neoplasm of ovary
0.772 0.228 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.771 0.228 0.000
T81.9 Unspecified complication of procedure
0.770 0.230 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.768 0.232 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.768 0.232 0.000
I72 Other aneurysm
0.767 0.233 0.000
I30 Acute pericarditis
0.765 0.235 0.000
Y84.2 Radiological procedure and radiotherapy
0.764 0.236 0.000
T90 Sequelae of injuries of head
0.762 0.238 0.000
M45 Ankylosing spondylitis
0.761 0.239 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.760 0.240 0.000
K63.0 Abscess of intestine
0.759 0.241 0.000
M48 Other spondylopathies
0.758 0.242 0.000
Chapter I Certain infectious and parasitic diseases
0.758 0.242 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.756 0.244 0.000
X60-X84 Intentional self-harm
0.754 0.246 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.753 0.247 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.752 0.248 0.000
K60 Fissure and fistula of anal and rectal regions
0.751 0.249 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.750 0.250 0.000
I45 Other conduction disorders
0.750 0.250 0.000
J09-J18 Influenza and pneumonia
0.750 0.250 0.000
S00.7 Multiple superficial injuries of head
0.749 0.251 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.748 0.252 0.000
M79.7 Fibromyalgia
0.748 0.252 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.748 0.252 0.000
M05-M14 Inflammatory polyarthropathies
0.745 0.255 0.000
M54.50 Low back pain (Multiple sites in spine)
0.745 0.255 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.745 0.255 0.000
M80-M85 Disorders of bone density and structure
0.744 0.256 0.000
K36 Other appendicitis
0.743 0.257 0.000
K70.3 Alcoholic cirrhosis of liver
0.742 0.258 0.000
C34.3 Lower lobe, bronchus or lung
0.741 0.259 0.000
Chapter XXII Codes for special purposes
0.741 0.259 0.000
Q61.0 Congenital single renal cyst
0.741 0.259 0.000
S00.5 Superficial injury of lip and oral cavity
0.741 0.259 0.000
I67.9 Cerebrovascular disease, unspecified
0.740 0.260 0.000
M54.2 Cervicalgia
0.740 0.260 0.000
K56.0 Paralytic ileus
0.739 0.261 0.000
Y52 Agents primarily affecting the cardiovascular system
0.738 0.262 0.000
M00-M03 Infectious arthropathies
0.735 0.265 0.000
C91 Lymphoid leukaemia
0.734 0.266 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.734 0.266 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.734 0.266 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.733 0.267 0.000
S69 Other and unspecified injuries of wrist and hand
0.733 0.267 0.000
D75 Other diseases of blood and blood-forming organs
0.732 0.268 0.000
Y44 Agents primarily affecting blood constituents
0.732 0.268 0.000
J95-J99 Other diseases of the respiratory system
0.731 0.269 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.731 0.269 0.000
S06.3 Focal brain injury
0.730 0.270 0.000
T79-T79 Certain early complications of trauma
0.729 0.270 0.000
Q61.2 Polycystic kidney, adult type
0.729 0.271 0.000
S01.8 Open wound of other parts of head
0.729 0.271 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.729 0.271 0.000
K38 Other diseases of appendix
0.728 0.272 0.000
D00-D09 In situ neoplasms
0.728 0.272 0.000
C60-C63 Malignant neoplasms of male genital organs
0.728 0.272 0.000
C34.0 Main bronchus
0.728 0.272 0.000
Y40 Systemic antibiotics
0.728 0.272 0.000
S01.5 Open wound of lip and oral cavity
0.727 0.273 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.727 0.273 0.000
Y85 Sequelae of transport accidents
0.726 0.273 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.726 0.274 0.000
K35.9 Acute appendicitis, unspecified
0.726 0.274 0.000
K63.9 Disease of intestine, unspecified
0.726 0.274 0.000
H92.0 Otalgia
0.724 0.276 0.000
I49.8 Other specified cardiac arrhythmias
0.724 0.276 0.000
T85.2 Mechanical complication of intraocular lens
0.724 0.276 0.000
C54 Malignant neoplasm of corpus uteri
0.723 0.277 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.722 0.278 0.000
S06.2 Diffuse brain injury
0.721 0.278 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.721 0.279 0.000
M79.64 Pain in limb (Hand)
0.721 0.279 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.720 0.280 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.719 0.281 0.000
Q61.3 Polycystic kidney, unspecified
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.717 0.283 0.000
W19 Unspecified fall
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.283 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.716 0.284 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.716 0.284 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.716 0.284 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.716 0.284 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.716 0.284 0.000
I95.1 Orthostatic hypotension
0.716 0.284 0.000
M53 Other dorsopathies, not elsewhere classified
0.715 0.285 0.000
W20-W49 Exposure to inanimate mechanical forces
0.715 0.285 0.000
M54.8 Other dorsalgia
0.714 0.286 0.000
M54.6 Pain in thoracic spine
0.714 0.286 0.000
M54.0 Panniculitis affecting regions of neck and back
0.714 0.286 0.000
K35.8 Acute appendicitis, other and unspecified
0.713 0.287 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.713 0.287 0.000
C79.2 Secondary malignant neoplasm of skin
0.713 0.287 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.713 0.287 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.713 0.287 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.713 0.287 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.713 0.287 0.000
K77 Liver disorders in diseases classified elsewhere
0.713 0.287 0.000
K73 Chronic hepatitis, not elsewhere classified
0.713 0.287 0.000
K71 Toxic liver disease
0.713 0.287 0.000
I74.5 Embolism and thrombosis of iliac artery
0.713 0.287 0.000
M40-M43 Deforming dorsopathies
0.713 0.287 0.000
F80-F89 Disorders of psychological development
0.712 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
F60-F69 Disorders of adult personality and behaviour
0.712 0.288 0.000
K75 Other inflammatory liver diseases
0.712 0.288 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.711 0.289 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.711 0.289 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.711 0.289 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.711 0.289 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.711 0.289 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.711 0.289 0.000
F11 Mental and behavioural disorders due to use of opioids
0.711 0.289 0.000
K74.6 Other and unspecified cirrhosis of liver
0.710 0.290 0.000
Y83.5 Amputation of limb(s)
0.710 0.290 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.710 0.290 0.000
S00.1 Contusion of eyelid and periocular area
0.710 0.290 0.000
I49.0 Ventricular fibrillation and flutter
0.710 0.290 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.710 0.290 0.000
K50-K52 Noninfective enteritis and colitis
0.709 0.291 0.000
K37 Unspecified appendicitis
0.709 0.291 0.000
C77.9 Lymph node, unspecified
0.709 0.291 0.000
Q00-Q07 Congenital malformations of the nervous system
0.708 0.292 0.000
S92 Fracture of foot, except ankle
0.708 0.292 0.000
K72.0 Acute and subacute hepatic failure
0.708 0.292 0.000
F10.9 Unspecified mental and behavioural disorder
0.707 0.293 0.000
F10.8 Other mental and behavioural disorders
0.707 0.293 0.000
F10.7 Residual and late-onset psychotic disorder
0.707 0.293 0.000
F10.6 Amnesic syndrome
0.707 0.293 0.000
F10.5 Psychotic disorder
0.707 0.293 0.000
F10.4 Withdrawal state with delirium
0.707 0.293 0.000
M46 Other inflammatory spondylopathies
0.707 0.293 0.000
S70-S79 Injuries to the hip and thigh
0.706 0.294 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.706 0.294 0.000
S08 Traumatic amputation of part of head
0.706 0.294 0.000
S07 Crushing injury of head
0.706 0.294 0.000
S05 Injury of eye and orbit
0.706 0.294 0.000
S04 Injury of cranial nerves
0.706 0.294 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.706 0.294 0.000
I78.1 Naevus, nonneoplastic
0.706 0.294 0.000
M79.69 Pain in limb (Site unspecified)
0.706 0.294 0.000
M79.60 Pain in limb (Multiple sites)
0.705 0.295 0.000
I71 Aortic aneurysm and dissection
0.705 0.295 0.000
I60 Subarachnoid haemorrhage
0.704 0.296 0.000
H91.9 Hearing loss, unspecified
0.704 0.296 0.000
M76 Enthesopathies of lower limb, excluding foot
0.704 0.296 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.704 0.296 0.000
M71 Other bursopathies
0.704 0.296 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.704 0.296 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.704 0.296 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.703 0.297 0.000
I99 Other and unspecified disorders of circulatory system
0.703 0.297 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.702 0.298 0.000
S00.0 Superficial injury of scalp
0.702 0.298 0.000
M79.9 Soft tissue disorder, unspecified
0.701 0.299 0.000
M79.5 Residual foreign body in soft tissue
0.701 0.299 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.701 0.299 0.000
M79.3 Panniculitis, unspecified
0.701 0.299 0.000
M79.1 Myalgia
0.701 0.299 0.000
K40-K46 Hernia
0.701 0.299 0.000
M54.55 Low back pain (Thoracolumbar region)
0.700 0.300 0.000
M54.54 Low back pain-Thoracic
0.700 0.300 0.000
M54.53 Low back pain-Cervicothoracic
0.700 0.300 0.000
M54.52 Low back pain-Cervical
0.700 0.300 0.000
M54.51 Low back pain-Occipit-atl-axl
0.700 0.300 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.700 0.300 0.000
K76.8 Other specified diseases of liver
0.699 0.300 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.302 0.000
S06.5 Traumatic subdural haemorrhage
0.697 0.303 0.000
M79.68 Pain in limb (Other)
0.697 0.303 0.000
M79.63 Pain in limb (Forearm)
0.697 0.303 0.000
M79.61 Pain in limb (Shoulder region)
0.697 0.303 0.000
Y83.9 Surgical procedure, unspecified
0.697 0.303 0.000
M49 Spondylopathies in diseases classified elsewhere
0.696 0.304 0.000
I46.9 Cardiac arrest, unspecified
0.696 0.304 0.000
I50 Heart failure
0.694 0.306 0.000
Y86 Sequelae of other accidents
0.694 0.306 0.000
C25 Malignant neoplasm of pancreas
0.693 0.307 0.000
M54.39 Sciatica (Site unspecified)
0.693 0.307 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.692 0.308 0.000
D55-D59 Haemolytic anaemias
0.692 0.308 0.000
I95.8 Other hypotension
0.691 0.309 0.000
I95.0 Idiopathic hypotension
0.691 0.309 0.000
C77.3 Axillary and upper limb lymph nodes
0.691 0.309 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.690 0.310 0.000
I61 Intracerebral haemorrhage
0.690 0.310 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.690 0.310 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.689 0.311 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.689 0.311 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.688 0.312 0.000
C78.2 Secondary malignant neoplasm of pleura
0.687 0.313 0.000
D72 Other disorders of white blood cells
0.687 0.313 0.000
K76.7 Hepatorenal syndrome
0.686 0.314 0.000
K76.5 Hepatic veno-occlusive disease
0.686 0.314 0.000
K76.4 Peliosis hepatis
0.686 0.314 0.000
K76.3 Infarction of liver
0.686 0.314 0.000
K76.2 Central haemorrhagic necrosis of liver
0.686 0.314 0.000
K76.1 Chronic passive congestion of liver
0.686 0.314 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.686 0.314 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.685 0.315 0.000
V20-V29 Motorcycle rider injured in transport accident
0.685 0.315 0.000
K65-K67 Diseases of peritoneum
0.685 0.315 0.000
F99-F99 Unspecified mental disorder
0.685 0.315 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.684 0.316 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.684 0.316 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.684 0.316 0.000
I52 Other heart disorders in diseases classified elsewhere
0.684 0.316 0.000
I48 Atrial fibrillation and flutter
0.684 0.316 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.684 0.316 0.000
I41 Myocarditis in diseases classified elsewhere
0.684 0.316 0.000
I40 Acute myocarditis
0.684 0.316 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.684 0.316 0.000
I37 Pulmonary valve disorders
0.684 0.316 0.000
I36 Nonrheumatic tricuspid valve disorders
0.684 0.316 0.000
I32 Pericarditis in diseases classified elsewhere
0.684 0.316 0.000
S20 Superficial injury of thorax
0.683 0.317 0.000
I33 Acute and subacute endocarditis
0.683 0.317 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.683 0.317 0.000
Q80-Q89 Other congenital malformations
0.683 0.317 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.683 0.317 0.000
Q50-Q56 Congenital malformations of genital organs
0.683 0.317 0.000
Q35-Q37 Cleft lip and cleft palate
0.683 0.317 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.683 0.317 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.683 0.317 0.000
J18 Pneumonia, organism unspecified
0.683 0.317 0.000
C77.1 Intrathoracic lymph nodes
0.683 0.317 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.681 0.319 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.681 0.319 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.681 0.319 0.000
C32 Malignant neoplasm of larynx
0.681 0.319 0.000
C31 Malignant neoplasm of accessory sinuses
0.681 0.319 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.681 0.319 0.000
C37 Malignant neoplasm of thymus
0.681 0.319 0.000
C33 Malignant neoplasm of trachea
0.681 0.319 0.000
K56.4 Other impaction of intestine
0.681 0.319 0.000
K56.3 Gallstone ileus
0.681 0.319 0.000
K56.1 Intussusception
0.681 0.319 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.681 0.319 0.000
T78 Adverse effects, not elsewhere classified
0.681 0.319 0.000
M79.62 Pain in limb (Upper arm)
0.679 0.320 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.679 0.321 0.000
D50-D53 Nutritional anaemias
0.679 0.321 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.678 0.321 0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.678 0.322 0.000
D80-D89 Certain disorders involving the immune mechanism
0.678 0.322 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.678 0.322 0.000
G61 Inflammatory polyneuropathy
0.678 0.322 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.676 0.324 0.000
K70.1 Alcoholic hepatitis
0.676 0.324 0.000
K70.0 Alcoholic fatty liver
0.676 0.324 0.000
V48 Car occupant injured in noncollision transport accident
0.675 0.325 0.000
S82 Fracture of lower leg, including ankle
0.674 0.326 0.000
Y83.3 Surgical operation with formation of external stoma
0.674 0.326 0.000
I49.9 Cardiac arrhythmia, unspecified
0.673 0.326 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.672 0.327 0.000
C80.9 Malignant neoplasm, unspecified
0.672 0.328 0.000
G93 Other disorders of brain
0.672 0.328 0.000
D64 Other anaemias
0.671 0.329 0.000
K63.4 Enteroptosis
0.671 0.329 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.670 0.329 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.670 0.329 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.670 0.329 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.670 0.329 0.000
M47.2 Other spondylosis with radiculopathy
0.670 0.329 0.000
M47.1 Other spondylosis with myelopathy
0.669 0.331 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.669 0.331 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.669 0.331 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.669 0.331 0.000
T51 Toxic effect of alcohol
0.669 0.331 0.000
G30-G32 Other degenerative diseases of the nervous system
0.667 0.332 0.000
S01.4 Open wound of cheek and temporomandibular area
0.667 0.333 0.000
A00-A09 Intestinal infectious diseases
0.667 0.333 0.000
I46.0 Cardiac arrest with successful resuscitation
0.666 0.334 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.666 0.334 0.000
S01.0 Open wound of scalp
0.666 0.334 0.000
S64 Injury of nerves at wrist and hand level
0.665 0.335 0.000
S50-S59 Injuries to the elbow and forearm
0.665 0.335 0.000
C77.8 Lymph nodes of multiple regions
0.664 0.335 0.000
T98 Sequelae of other and unspecified effects of external causes
0.664 0.336 0.000
T95 Sequelae of burns, corrosions and frostbite
0.664 0.336 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.664 0.336 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.664 0.336 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.664 0.336 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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