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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117073822
log Bayes Factor = 14.7798
Chromosome 16   position 21,337,217  (GRCh37) Explore rs117073822 on Ensembl!
Variant rs117073822 is part of Cluster X0083

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
M15-M19 Arthrosis
0.995 0.005 0.000
M19 Other arthrosis
0.995 0.005 0.000
M19.9 Arthrosis, unspecified
0.994 0.006 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.992 0.008 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
Chapter V Mental and behavioural disorders
0.989 0.011 0.000
I67 Other cerebrovascular diseases
0.988 0.012 0.000
Chapter X Diseases of the respiratory system
0.980 0.020 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.979 0.021 0.000
I67.9 Cerebrovascular disease, unspecified
0.979 0.021 0.000
Chapter XIV Diseases of the genitourinary system
0.978 0.022 0.000
I30-I52 Other forms of heart disease
0.976 0.024 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.975 0.025 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.974 0.026 0.000
N17-N19 Renal failure
0.974 0.026 0.000
J09-J18 Influenza and pneumonia
0.974 0.026 0.000
I50 Heart failure
0.972 0.028 0.000
R30-R39 Symptoms and signs involving the urinary system
0.968 0.032 0.000
N17 Acute renal failure
0.967 0.033 0.000
M45-M49 Spondylopathies
0.967 0.033 0.000
N17.9 Acute renal failure, unspecified
0.963 0.037 0.000
I95 Hypotension
0.960 0.040 0.000
R33 Retention of urine
0.959 0.041 0.000
J18 Pneumonia, organism unspecified
0.951 0.049 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.948 0.052 0.000
Chapter VI Diseases of the nervous system
0.946 0.054 0.000
I95.9 Hypotension, unspecified
0.944 0.056 0.000
I50.0 Congestive heart failure
0.944 0.056 0.000
I50.9 Heart failure, unspecified
0.942 0.058 0.000
I69 Sequelae of cerebrovascular disease
0.941 0.059 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.936 0.064 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.929 0.071 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.928 0.072 0.000
S60-S69 Injuries to the wrist and hand
0.928 0.072 0.000
R47-R49 Symptoms and signs involving speech and voice
0.919 0.081 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.914 0.086 0.000
S70-S79 Injuries to the hip and thigh
0.912 0.088 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.912 0.088 0.000
I71 Aortic aneurysm and dissection
0.912 0.088 0.000
T66-T78 Other and unspecified effects of external causes
0.911 0.089 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.906 0.094 0.000
F41 Other anxiety disorders
0.905 0.095 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.900 0.100 0.000
J18.1 Lobar pneumonia, unspecified
0.899 0.101 0.000
I42 Cardiomyopathy
0.897 0.103 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.893 0.107 0.000
S40-S49 Injuries to the shoulder and upper arm
0.884 0.116 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.884 0.116 0.000
M19.0 Primary arthrosis of other joints
0.882 0.118 0.000
Chapter I Certain infectious and parasitic diseases
0.874 0.126 0.000
Chapter II Neoplasms
0.873 0.127 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.870 0.130 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.868 0.132 0.000
M47 Spondylosis
0.863 0.137 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.860 0.140 0.000
R79 Other abnormal findings of blood chemistry
0.860 0.140 0.000
C51-C58 Malignant neoplasms of female genital organs
0.860 0.140 0.000
S80-S89 Injuries to the knee and lower leg
0.855 0.145 0.000
M48 Other spondylopathies
0.854 0.146 0.000
F41.9 Anxiety disorder, unspecified
0.851 0.149 0.000
W00-W19 Falls
0.851 0.149 0.000
M65-M68 Disorders of synovium and tendon
0.851 0.149 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.849 0.151 0.000
R47 Speech disturbances, not elsewhere classified
0.848 0.152 0.000
F30-F39 Mood [affective] disorders
0.845 0.155 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.841 0.159 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.841 0.159 0.000
M80-M85 Disorders of bone density and structure
0.840 0.159 0.000
I61 Intracerebral haemorrhage
0.839 0.161 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.839 0.161 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.838 0.162 0.000
Chapter XXII Codes for special purposes
0.837 0.163 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.835 0.165 0.000
R30 Pain associated with micturition
0.833 0.167 0.000
S90-S99 Injuries to the ankle and foot
0.831 0.169 0.000
C54 Malignant neoplasm of corpus uteri
0.828 0.172 0.000
T78 Adverse effects, not elsewhere classified
0.827 0.173 0.000
W20-W49 Exposure to inanimate mechanical forces
0.826 0.174 0.000
F41.2 Mixed anxiety and depressive disorder
0.822 0.178 0.000
M86-M90 Other osteopathies
0.821 0.179 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.820 0.180 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.818 0.182 0.000
J40-J47 Chronic lower respiratory diseases
0.818 0.182 0.000
S72 Fracture of femur
0.817 0.183 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.817 0.183 0.000
N19 Unspecified renal failure
0.815 0.185 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.814 0.186 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.813 0.187 0.000
J30-J39 Other diseases of upper respiratory tract
0.811 0.189 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.811 0.189 0.000
I63 Cerebral infarction
0.811 0.189 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.807 0.193 0.000
C54.1 Endometrium
0.806 0.194 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.806 0.194 0.000
J18.0 Bronchopneumonia, unspecified
0.805 0.195 0.000
N00-N08 Glomerular diseases
0.802 0.198 0.000
R29.6 Tendency to fall, not elsewhere classified
0.799 0.201 0.000
J44 Other chronic obstructive pulmonary disease
0.799 0.201 0.000
I42.0 Dilated cardiomyopathy
0.798 0.202 0.000
J18.9 Pneumonia, unspecified
0.797 0.203 0.000
I78 Diseases of capillaries
0.796 0.204 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.794 0.206 0.000
R26 Abnormalities of gait and mobility
0.790 0.210 0.000
F22 Persistent delusional disorders
0.790 0.210 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.788 0.212 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.788 0.212 0.000
V20-V29 Motorcycle rider injured in transport accident
0.787 0.213 0.000
M40-M43 Deforming dorsopathies
0.787 0.213 0.000
I67.2 Cerebral atherosclerosis
0.782 0.218 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.781 0.219 0.000
L20-L30 Dermatitis and eczema
0.780 0.220 0.000
M45 Ankylosing spondylitis
0.779 0.221 0.000
L50-L54 Urticaria and erythema
0.778 0.222 0.000
I74 Arterial embolism and thrombosis
0.775 0.225 0.000
J33 Nasal polyp
0.775 0.225 0.000
F43 Reaction to severe stress, and adjustment disorders
0.775 0.225 0.000
R47.8 Other and unspecified speech disturbances
0.773 0.227 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.772 0.227 0.000
M48.0 Spinal stenosis
0.772 0.228 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.768 0.232 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.767 0.233 0.000
M19.94 Arthrosis, unspecified (Hand)
0.760 0.239 0.000
G30-G32 Other degenerative diseases of the nervous system
0.760 0.240 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.760 0.240 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.760 0.240 0.000
S10-S19 Injuries to the neck
0.758 0.242 0.000
Y40 Systemic antibiotics
0.755 0.245 0.000
T79-T79 Certain early complications of trauma
0.754 0.245 0.000
M47.8 Other spondylosis
0.754 0.246 0.000
I42.9 Cardiomyopathy, unspecified
0.753 0.247 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.753 0.247 0.000
R35 Polyuria
0.752 0.248 0.000
F20 Schizophrenia
0.752 0.248 0.000
A00-A09 Intestinal infectious diseases
0.752 0.248 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.751 0.249 0.000
M05-M14 Inflammatory polyarthropathies
0.751 0.249 0.000
M46 Other inflammatory spondylopathies
0.751 0.249 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.750 0.249 0.000
I49 Other cardiac arrhythmias
0.750 0.250 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.750 0.250 0.000
M00-M03 Infectious arthropathies
0.749 0.251 0.000
L40-L45 Papulosquamous disorders
0.749 0.251 0.000
I77 Other disorders of arteries and arterioles
0.748 0.252 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.748 0.252 0.000
I60 Subarachnoid haemorrhage
0.748 0.252 0.000
J60-J70 Lung diseases due to external agents
0.747 0.253 0.000
I50.1 Left ventricular failure
0.746 0.254 0.000
I72 Other aneurysm
0.746 0.254 0.000
B35-B49 Mycoses
0.746 0.254 0.000
R41.0 Disorientation, unspecified
0.744 0.256 0.000
S62 Fracture at wrist and hand level
0.743 0.257 0.000
F40 Phobic anxiety disorders
0.743 0.257 0.000
N18 Chronic renal failure
0.742 0.258 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.742 0.258 0.000
S67 Crushing injury of wrist and hand
0.741 0.259 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.741 0.259 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.739 0.261 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.739 0.261 0.000
I67.8 Other specified cerebrovascular diseases
0.739 0.261 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.738 0.262 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.737 0.263 0.000
M20-M25 Other joint disorders
0.737 0.263 0.000
Y52 Agents primarily affecting the cardiovascular system
0.736 0.263 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.736 0.263 0.000
J35 Chronic diseases of tonsils and adenoids
0.736 0.264 0.000
Y57 Other and unspecified drugs and medicaments
0.735 0.265 0.000
R45 Symptoms and signs involving emotional state
0.734 0.266 0.000
S82 Fracture of lower leg, including ankle
0.734 0.266 0.000
F33 Recurrent depressive disorder
0.734 0.266 0.000
S20-S29 Injuries to the thorax
0.733 0.267 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.733 0.267 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.732 0.268 0.000
J15.4 Pneumonia due to other streptococci
0.731 0.269 0.000
S71 Open wound of hip and thigh
0.731 0.269 0.000
I95.1 Orthostatic hypotension
0.730 0.270 0.000
X60-X84 Intentional self-harm
0.730 0.270 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.730 0.270 0.000
L30 Other dermatitis
0.729 0.271 0.000
R49 Voice disturbances
0.728 0.272 0.000
J11 Influenza, virus not identified
0.728 0.272 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.726 0.274 0.000
T78.2 Anaphylactic shock, unspecified
0.724 0.276 0.000
C56 Malignant neoplasm of ovary
0.724 0.276 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.722 0.278 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.722 0.278 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.722 0.278 0.000
D00-D09 In situ neoplasms
0.722 0.278 0.000
I31 Other diseases of pericardium
0.720 0.280 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.720 0.280 0.000
I69.3 Sequelae of cerebral infarction
0.719 0.281 0.000
R30.0 Dysuria
0.718 0.282 0.000
M18 Arthrosis of first carpometacarpal joint
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
S68 Traumatic amputation of wrist and hand
0.717 0.283 0.000
T68 Hypothermia
0.716 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.715 0.284 0.000
G70-G73 Diseases of myoneural junction and muscle
0.715 0.285 0.000
F60-F69 Disorders of adult personality and behaviour
0.715 0.285 0.000
R42 Dizziness and giddiness
0.715 0.285 0.000
C15-C26 Malignant neoplasms of digestive organs
0.714 0.286 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.714 0.286 0.000
M15 Polyarthrosis
0.713 0.286 0.000
M19.8 Other specified arthrosis
0.713 0.287 0.000
M19.2 Other secondary arthrosis
0.713 0.287 0.000
M19.1 Posttraumatic arthrosis of other joints
0.713 0.287 0.000
M19.98 Arthrosis, unspecified (Other)
0.713 0.287 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.713 0.287 0.000
S72.1 Pertrochanteric fracture
0.712 0.288 0.000
F22.0 Delusional disorder
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.711 0.289 0.000
R32 Unspecified urinary incontinence
0.710 0.290 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.709 0.290 0.000
F99-F99 Unspecified mental disorder
0.709 0.291 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
R25 Abnormal involuntary movements
0.709 0.291 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.708 0.292 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.708 0.292 0.000
I67.5 Moyamoya disease
0.708 0.292 0.000
I67.4 Hypertensive encephalopathy
0.708 0.292 0.000
I67.3 Progressive vascular leukoencephalopathy
0.708 0.292 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.708 0.292 0.000
A04 Other bacterial intestinal infections
0.707 0.293 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.707 0.293 0.000
N99-N99 Other disorders of the genitourinary system
0.707 0.293 0.000
C64-C68 Malignant neoplasms of urinary tract
0.706 0.294 0.000
M65 Synovitis and tenosynovitis
0.704 0.296 0.000
J33.9 Nasal polyp, unspecified
0.704 0.296 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.704 0.296 0.000
I73 Other peripheral vascular diseases
0.703 0.296 0.000
W19 Unspecified fall
0.703 0.297 0.000
Y86 Sequelae of other accidents
0.703 0.297 0.000
N76 Other inflammation of vagina and vulva
0.703 0.297 0.000
I99 Other and unspecified disorders of circulatory system
0.702 0.298 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.702 0.298 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.701 0.299 0.000
M81 Osteoporosis without pathological fracture
0.700 0.300 0.000
T92 Sequelae of injuries of upper limb
0.700 0.300 0.000
I52 Other heart disorders in diseases classified elsewhere
0.700 0.300 0.000
I48 Atrial fibrillation and flutter
0.700 0.300 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.700 0.300 0.000
I41 Myocarditis in diseases classified elsewhere
0.700 0.300 0.000
I40 Acute myocarditis
0.700 0.300 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.700 0.300 0.000
I37 Pulmonary valve disorders
0.700 0.300 0.000
I36 Nonrheumatic tricuspid valve disorders
0.700 0.300 0.000
I33 Acute and subacute endocarditis
0.700 0.300 0.000
I32 Pericarditis in diseases classified elsewhere
0.700 0.300 0.000
I30 Acute pericarditis
0.700 0.300 0.000
T87 Complications peculiar to reattachment and amputation
0.699 0.301 0.000
T86 Failure and rejection of transplanted organs and tissues
0.699 0.301 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.699 0.301 0.000
M50-M54 Other dorsopathies
0.698 0.302 0.000
J17 Pneumonia in diseases classified elsewhere
0.698 0.302 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.698 0.302 0.000
J12 Viral pneumonia, not elsewhere classified
0.698 0.302 0.000
J10 Influenza due to identified influenza virus
0.698 0.302 0.000
J14 Pneumonia due to Haemophilus influenzae
0.698 0.302 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.698 0.302 0.000
J09 Influenza due to certain identified influenza virus
0.698 0.302 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.696 0.304 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.696 0.304 0.000
I95.2 Hypotension due to drugs
0.696 0.304 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.695 0.305 0.000
S42 Fracture of shoulder and upper arm
0.695 0.305 0.000
R36 Urethral discharge
0.694 0.306 0.000
R34 Anuria and oliguria
0.694 0.306 0.000
M88 Paget's disease of bone [osteitis deformans]
0.694 0.306 0.000
N17.8 Other acute renal failure
0.694 0.306 0.000
N17.2 Acute renal failure with medullary necrosis
0.694 0.306 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.694 0.306 0.000
N17.0 Acute renal failure with tubular necrosis
0.694 0.306 0.000
M49 Spondylopathies in diseases classified elsewhere
0.693 0.306 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.693 0.307 0.000
L30.9 Dermatitis, unspecified
0.693 0.307 0.000
G90-G99 Other disorders of the nervous system
0.692 0.307 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.691 0.309 0.000
N25-N29 Other disorders of kidney and ureter
0.691 0.309 0.000
G62 Other polyneuropathies
0.691 0.309 0.000
I44 Atrioventricular and left bundle-branch block
0.691 0.309 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.691 0.309 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.691 0.309 0.000
I95.8 Other hypotension
0.689 0.311 0.000
I95.0 Idiopathic hypotension
0.689 0.311 0.000
T78.4 Allergy, unspecified
0.689 0.311 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.687 0.313 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.686 0.314 0.000
L50 Urticaria
0.685 0.315 0.000
I62 Other nontraumatic intracranial haemorrhage
0.684 0.316 0.000
V10-V19 Pedal cyclist injured in transport accident
0.684 0.316 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.683 0.317 0.000
J18.8 Other pneumonia, organism unspecified
0.682 0.318 0.000
J18.2 Hypostatic pneumonia, unspecified
0.682 0.318 0.000
F48 Other neurotic disorders
0.680 0.320 0.000
F44 Dissociative [conversion] disorders
0.680 0.320 0.000
F42 Obsessive-compulsive disorder
0.680 0.320 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.680 0.320 0.000
J33.0 Polyp of nasal cavity
0.680 0.320 0.000
R40 Somnolence, stupor and coma
0.679 0.320 0.000
S81 Open wound of lower leg
0.679 0.321 0.000
Y44 Agents primarily affecting blood constituents
0.678 0.322 0.000
G81 Hemiplegia
0.677 0.323 0.000
J35.0 Chronic tonsillitis
0.676 0.324 0.000
M67 Other disorders of synovium and tendon
0.675 0.325 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.675 0.325 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.675 0.325 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.675 0.325 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.675 0.325 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.675 0.325 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.674 0.326 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.673 0.327 0.000
T98 Sequelae of other and unspecified effects of external causes
0.673 0.327 0.000
S61 Open wound of wrist and hand
0.672 0.328 0.000
W22 Striking against or struck by other objects
0.672 0.328 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.671 0.329 0.000
S70 Superficial injury of hip and thigh
0.669 0.331 0.000
M47.1 Other spondylosis with myelopathy
0.669 0.331 0.000
L40 Psoriasis
0.668 0.332 0.000
S00-S09 Injuries to the head
0.668 0.332 0.000
S72.0 Fracture of neck of femur
0.667 0.332 0.000
I78.1 Naevus, nonneoplastic
0.667 0.333 0.000
N03 Chronic nephritic syndrome
0.667 0.333 0.000
W25 Contact with sharp glass
0.667 0.333 0.000
W06 Fall involving bed
0.666 0.334 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.665 0.334 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.665 0.334 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.665 0.334 0.000
S69 Other and unspecified injuries of wrist and hand
0.665 0.334 0.000
S65 Injury of blood vessels at wrist and hand level
0.665 0.334 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.665 0.334 0.000
S60 Superficial injury of wrist and hand
0.665 0.334 0.000
M41 Scoliosis
0.665 0.335 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.665 0.335 0.000
M47.9 Spondylosis, unspecified
0.664 0.336 0.000
I70 Atherosclerosis
0.663 0.337 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.663 0.337 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.663 0.337 0.000
T93 Sequelae of injuries of lower limb
0.663 0.337 0.000
S92 Fracture of foot, except ankle
0.663 0.337 0.000
S91 Open wound of ankle and foot
0.662 0.338 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.660 0.340 0.000
A80-A89 Viral infections of the central nervous system
0.660 0.340 0.000
M84 Disorders of continuity of bone
0.660 0.340 0.000
N75 Diseases of Bartholin's gland
0.660 0.340 0.000
A04.5 Campylobacter enteritis
0.660 0.340 0.000
S82.6 Fracture of lateral malleolus
0.659 0.341 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.659 0.341 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.659 0.341 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.658 0.342 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.658 0.342 0.000
M25 Other joint disorders, not elsewhere classified
0.657 0.343 0.000
M48.09 Spinal stenosis (Site unspecified)
0.657 0.343 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.656 0.344 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.655 0.345 0.000
R77 Other abnormalities of plasma proteins
0.655 0.345 0.000
R76 Other abnormal immunological findings in serum
0.655 0.345 0.000
R74 Abnormal serum enzyme levels
0.655 0.345 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.655 0.345 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.655 0.345 0.000
R71 Abnormality of red blood cells
0.655 0.345 0.000
R47.1 Dysarthria and anarthria
0.655 0.345 0.000
S79 Other and unspecified injuries of hip and thigh
0.654 0.346 0.000
S78 Traumatic amputation of hip and thigh
0.654 0.346 0.000
S77 Crushing injury of hip and thigh
0.654 0.346 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.654 0.346 0.000
S75 Injury of blood vessels at hip and thigh level
0.654 0.346 0.000
S74 Injury of nerves at hip and thigh level
0.654 0.346 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.654 0.346 0.000
R46 Symptoms and signs involving appearance and behaviour
0.654 0.346 0.000
R43 Disturbances of smell and taste
0.654 0.346 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.654 0.346 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.654 0.346 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.654 0.346 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.654 0.346 0.000
I71.0 Dissection of aorta [any part]
0.654 0.346 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.654 0.346 0.000
B37 Candidiasis
0.654 0.346 0.000
T75 Effects of other external causes
0.653 0.346 0.000
T74 Maltreatment syndromes
0.653 0.346 0.000
T73 Effects of other deprivation
0.653 0.346 0.000
T70 Effects of air pressure and water pressure
0.653 0.346 0.000
T69 Other effects of reduced temperature
0.653 0.346 0.000
T67 Effects of heat and light
0.653 0.346 0.000
T71 Asphyxiation
0.653 0.346 0.000
T66 Unspecified effects of radiation
0.653 0.346 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.652 0.348 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.651 0.349 0.000
F43.2 Adjustment disorders
0.650 0.350 0.000
J15.9 Bacterial pneumonia, unspecified
0.650 0.350 0.000
J15.8 Other bacterial pneumonia
0.650 0.350 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.650 0.350 0.000
J15.5 Pneumonia due to Escherichia coli
0.650 0.350 0.000
J15.3 Pneumonia due to streptococcus, group B
0.650 0.350 0.000
J15.2 Pneumonia due to staphylococcus
0.650 0.350 0.000
J15.1 Pneumonia due to Pseudomonas
0.650 0.350 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.650 0.350 0.000
F41.8 Other specified anxiety disorders
0.649 0.351 0.000
F41.3 Other mixed anxiety disorders
0.649 0.351 0.000
F41.1 Generalised anxiety disorder
0.649 0.351 0.000
C53 Malignant neoplasm of cervix uteri
0.648 0.352 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.648 0.352 0.000
N10-N16 Renal tubulo-interstitial diseases
0.647 0.353 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.646 0.354 0.000
G40-G47 Episodic and paroxysmal disorders
0.645 0.355 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.645 0.355 0.000
F25 Schizoaffective disorders
0.645 0.355 0.000
F23 Acute and transient psychotic disorders
0.645 0.355 0.000
F29 Unspecified nonorganic psychosis
0.645 0.355 0.000
F28 Other nonorganic psychotic disorders
0.645 0.355 0.000
F24 Induced delusional disorder
0.645 0.355 0.000
F21 Schizotypal disorder
0.645 0.355 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.645 0.355 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.645 0.355 0.000
R47.0 Dysphasia and aphasia
0.644 0.355 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.644 0.356 0.000
I42.8 Other cardiomyopathies
0.643 0.357 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.643 0.357 0.000
I42.6 Alcoholic cardiomyopathy
0.643 0.357 0.000
I42.5 Other restrictive cardiomyopathy
0.643 0.357 0.000
I42.4 Endocardial fibroelastosis
0.643 0.357 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.643 0.357 0.000
I42.2 Other hypertrophic cardiomyopathy
0.643 0.357 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.643 0.357 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.642 0.358 0.000
F20.0 Paranoid schizophrenia
0.642 0.358 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.641 0.359 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.641 0.359 0.000
C20 Malignant neoplasm of rectum
0.641 0.359 0.000
Y59 Other and unspecified vaccines and biological substances
0.640 0.360 0.000
Y58 Bacterial vaccines
0.640 0.360 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.640 0.360 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.640 0.360 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.640 0.360 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.640 0.360 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.640 0.360 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.640 0.360 0.000
Y48 Anaesthetics and therapeutic gases
0.640 0.360 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.640 0.360 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.640 0.360 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.640 0.360 0.000
W10 Fall on and from stairs and steps
0.639 0.361 0.000
B25-B34 Other viral diseases
0.639 0.361 0.000
Y40.0 Penicillins
0.638 0.362 0.000
S72.10 Pertrochanteric fracture (closed)
0.637 0.363 0.000
J43 Emphysema
0.637 0.363 0.000
M85 Other disorders of bone density and structure
0.635 0.365 0.000
R30.9 Painful micturition, unspecified
0.635 0.365 0.000
F32 Depressive episode
0.634 0.366 0.000
S48 Traumatic amputation of shoulder and upper arm
0.634 0.366 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.634 0.366 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.634 0.366 0.000
S44 Injury of nerves at shoulder and upper arm level
0.634 0.366 0.000
S41 Open wound of shoulder and upper arm
0.634 0.366 0.000
S40 Superficial injury of shoulder and upper arm
0.634 0.366 0.000
S47 Crushing injury of shoulder and upper arm
0.634 0.366 0.000
L10-L14 Bullous disorders
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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