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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117127635
log Bayes Factor = 12.0334
Chromosome 18   position 56,130,563  (GRCh37) Explore rs117127635 on Ensembl!
Variant rs117127635 is part of Cluster X0133

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.994 0.006 0.000
C15-C26 Malignant neoplasms of digestive organs
0.994 0.006 0.000
Chapter X Diseases of the respiratory system
0.993 0.007 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.991 0.009 0.000
N30-N39 Other diseases of urinary system
0.988 0.012 0.000
C79 Secondary malignant neoplasm of other sites
0.987 0.013 0.000
N32 Other disorders of bladder
0.986 0.014 0.000
M50-M54 Other dorsopathies
0.986 0.014 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.983 0.017 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.976 0.024 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.974 0.026 0.000
D68 Other coagulation defects
0.971 0.029 0.000
M70-M79 Other soft tissue disorders
0.970 0.030 0.000
M20-M25 Other joint disorders
0.969 0.031 0.000
J95-J99 Other diseases of the respiratory system
0.968 0.032 0.000
Chapter XX External causes of morbidity and mortality
0.966 0.034 0.000
N32.3 Diverticulum of bladder
0.966 0.034 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.961 0.039 0.000
N32.9 Bladder disorder, unspecified
0.955 0.045 0.000
M51 Other intervertebral disk disorders
0.953 0.047 0.000
J98 Other respiratory disorders
0.952 0.048 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.952 0.048 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.950 0.050 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.946 0.054 0.000
D68.2 Hereditary deficiency of other clotting factors
0.943 0.057 0.000
C18 Malignant neoplasm of colon
0.943 0.057 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.940 0.060 0.000
M51.2 Other specified intervertebral disk displacement
0.936 0.064 0.000
D45 Polycythaemia vera
0.933 0.067 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.933 0.067 0.000
N32.8 Other specified disorders of bladder
0.931 0.069 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.928 0.072 0.000
J98.1 Pulmonary collapse
0.926 0.074 0.000
M79.6 Pain in limb
0.918 0.082 0.000
M25 Other joint disorders, not elsewhere classified
0.913 0.087 0.000
C15 Malignant neoplasm of oesophagus
0.910 0.090 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.910 0.090 0.000
C91 Lymphoid leukaemia
0.904 0.096 0.000
J30-J39 Other diseases of upper respiratory tract
0.903 0.097 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.902 0.098 0.000
M05-M14 Inflammatory polyarthropathies
0.899 0.101 0.000
N25-N29 Other disorders of kidney and ureter
0.894 0.106 0.000
D00-D09 In situ neoplasms
0.893 0.107 0.000
M22 Disorders of patella
0.887 0.113 0.000
C79.2 Secondary malignant neoplasm of skin
0.886 0.114 0.000
C64-C68 Malignant neoplasms of urinary tract
0.883 0.117 0.000
M79.8 Other specified soft tissue disorders
0.883 0.117 0.000
M21 Other acquired deformities of limbs
0.881 0.119 0.000
C78.7 Secondary malignant neoplasm of liver
0.879 0.121 0.000
C90.0 Multiple myeloma
0.876 0.124 0.000
J32 Chronic sinusitis
0.876 0.124 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.876 0.124 0.000
M06 Other rheumatoid arthritis
0.875 0.125 0.000
N17-N19 Renal failure
0.874 0.126 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.871 0.129 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.869 0.131 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.866 0.134 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.865 0.135 0.000
M65-M68 Disorders of synovium and tendon
0.865 0.135 0.000
M25.7 Osteophyte
0.864 0.136 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.861 0.139 0.000
J32.9 Chronic sinusitis, unspecified
0.858 0.142 0.000
M06.9 Rheumatoid arthritis, unspecified
0.858 0.142 0.000
C78.2 Secondary malignant neoplasm of pleura
0.857 0.143 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.856 0.144 0.000
J33 Nasal polyp
0.853 0.147 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.852 0.148 0.000
N17 Acute renal failure
0.852 0.148 0.000
M50 Cervical disk disorders
0.852 0.148 0.000
D68.9 Coagulation defect, unspecified
0.845 0.155 0.000
C18.9 Colon, unspecified
0.841 0.159 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.839 0.161 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.838 0.162 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.837 0.163 0.000
M60-M63 Disorders of muscles
0.837 0.163 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.836 0.164 0.000
N17.9 Acute renal failure, unspecified
0.834 0.166 0.000
N00-N08 Glomerular diseases
0.831 0.169 0.000
D68.6 Other Thrombophilia
0.830 0.170 0.000
M79.62 Pain in limb (Upper arm)
0.830 0.170 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.830 0.170 0.000
J90-J94 Other diseases of pleura
0.828 0.172 0.000
C91.1 Chronic lymphocytic leukaemia
0.827 0.173 0.000
N60-N64 Disorders of breast
0.826 0.174 0.000
D68.8 Other specified coagulation defects
0.823 0.177 0.000
W00-W19 Falls
0.820 0.180 0.000
C15.9 Oesophagus, unspecified
0.817 0.183 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.817 0.183 0.000
M54 Dorsalgia
0.816 0.184 0.000
C78.0 Secondary malignant neoplasm of lung
0.816 0.184 0.000
M45-M49 Spondylopathies
0.815 0.185 0.000
C77.0 Lymph nodes of head, face and neck
0.814 0.186 0.000
C25 Malignant neoplasm of pancreas
0.814 0.186 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.811 0.189 0.000
J33.8 Other polyp of sinus
0.810 0.190 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.808 0.192 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.807 0.193 0.000
M79.0 Rheumatism, unspecified
0.806 0.194 0.000
M30 Polyarteritis nodosa and related conditions
0.805 0.195 0.000
D47.1 Chronic myeloproliferative disease
0.802 0.198 0.000
M24 Other specific joint derangements
0.801 0.199 0.000
Y40 Systemic antibiotics
0.798 0.202 0.000
Chapter I Certain infectious and parasitic diseases
0.796 0.204 0.000
M65 Synovitis and tenosynovitis
0.796 0.204 0.000
M22.4 Chondromalacia patellae
0.795 0.205 0.000
C92 Myeloid leukaemia
0.794 0.206 0.000
M40-M43 Deforming dorsopathies
0.794 0.206 0.000
C16 Malignant neoplasm of stomach
0.794 0.206 0.000
D68.5 Primary Thrombophilia
0.793 0.207 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.789 0.211 0.000
J98.6 Disorders of diaphragm
0.788 0.212 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.788 0.212 0.000
M80-M85 Disorders of bone density and structure
0.786 0.214 0.000
M54.5 Low back pain
0.783 0.217 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.783 0.217 0.000
M79.1 Myalgia
0.782 0.218 0.000
J92 Pleural plaque
0.780 0.220 0.000
M50.1 Cervical disk disorder with radiculopathy
0.780 0.220 0.000
D47.4 Osteomyelofibrosis
0.779 0.221 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.778 0.222 0.000
M91-M94 Chondropathies
0.778 0.222 0.000
J86 Pyothorax
0.775 0.225 0.000
Chapter VIII Diseases of the ear and mastoid process
0.773 0.227 0.000
S00-S09 Injuries to the head
0.772 0.228 0.000
V40-V49 Car occupant injured in transport accident
0.770 0.230 0.000
C67 Malignant neoplasm of bladder
0.770 0.230 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.769 0.231 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.769 0.231 0.000
M79.60 Pain in limb (Multiple sites)
0.768 0.232 0.000
D69 Purpura and other haemorrhagic conditions
0.768 0.232 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.764 0.236 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.764 0.236 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.763 0.237 0.000
C90.2 Plasmacytoma, extramedullary
0.763 0.237 0.000
O24 Diabetes mellitus in pregnancy
0.762 0.238 0.000
J37 Chronic laryngitis and laryngotracheitis
0.762 0.238 0.000
M54.59 Low back pain (Site unspecified)
0.760 0.240 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.759 0.240 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.759 0.241 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.759 0.241 0.000
C32 Malignant neoplasm of larynx
0.758 0.242 0.000
C77.2 Intra-abdominal lymph nodes
0.758 0.242 0.000
D66 Hereditary factor VIII deficiency
0.757 0.243 0.000
D09 Carcinoma in situ of other and unspecified sites
0.757 0.243 0.000
M00-M03 Infectious arthropathies
0.756 0.243 0.000
M47 Spondylosis
0.755 0.245 0.000
O26.9 Pregnancy-related condition, unspecified
0.755 0.245 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.753 0.247 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.753 0.247 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.752 0.248 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.751 0.249 0.000
C15.4 Middle third of oesophagus
0.750 0.250 0.000
Q50-Q56 Congenital malformations of genital organs
0.749 0.250 0.000
O85-O92 Complications predominantly related to the puerperium
0.749 0.251 0.000
J92.9 Pleural plaque without asbestos
0.748 0.252 0.000
S00 Superficial injury of head
0.746 0.254 0.000
C18.7 Sigmoid colon
0.744 0.256 0.000
J09-J18 Influenza and pneumonia
0.742 0.258 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.740 0.260 0.000
C20 Malignant neoplasm of rectum
0.740 0.260 0.000
C88 Malignant immunoproliferative diseases
0.740 0.260 0.000
D37.7 Other digestive organs
0.738 0.261 0.000
M34 Systemic sclerosis
0.738 0.262 0.000
N28.8 Other specified disorders of kidney and ureter
0.736 0.264 0.000
M51.9 Intervertebral disk disorder, unspecified
0.734 0.266 0.000
M21.1 Varus deformity, not elsewhere classified
0.734 0.266 0.000
A30-A49 Other bacterial diseases
0.734 0.266 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.732 0.268 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.731 0.269 0.000
M25.71 Osteophyte (Shoulder region)
0.731 0.269 0.000
C22.1 Intrahepatic bile duct carcinoma
0.730 0.270 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.729 0.271 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.729 0.271 0.000
C21 Malignant neoplasm of anus and anal canal
0.729 0.271 0.000
M25.9 Joint disorder, unspecified
0.728 0.272 0.000
Q00-Q07 Congenital malformations of the nervous system
0.725 0.274 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.725 0.275 0.000
J00-J06 Acute upper respiratory infections
0.725 0.275 0.000
N28.1 Cyst of kidney, acquired
0.724 0.276 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.724 0.276 0.000
C18.2 Ascending colon
0.723 0.277 0.000
D03 Melanoma in situ
0.722 0.278 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.721 0.279 0.000
M79.69 Pain in limb (Site unspecified)
0.720 0.280 0.000
Y57 Other and unspecified drugs and medicaments
0.720 0.280 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.719 0.281 0.000
J98.4 Other disorders of lung
0.718 0.282 0.000
Y00-Y09 Assault
0.718 0.282 0.000
Y40.9 Systemic antibiotic, unspecified
0.718 0.282 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.718 0.282 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.717 0.282 0.000
L20-L30 Dermatitis and eczema
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
N34 Urethritis and urethral syndrome
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.715 0.284 0.000
M77 Other enthesopathies
0.715 0.285 0.000
M47.9 Spondylosis, unspecified
0.715 0.285 0.000
N99-N99 Other disorders of the genitourinary system
0.715 0.285 0.000
N30 Cystitis
0.715 0.285 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.714 0.285 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.714 0.286 0.000
C18.0 Caecum
0.714 0.286 0.000
V10-V19 Pedal cyclist injured in transport accident
0.714 0.286 0.000
S90-S99 Injuries to the ankle and foot
0.714 0.286 0.000
W20-W49 Exposure to inanimate mechanical forces
0.714 0.286 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.713 0.287 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.713 0.287 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.713 0.287 0.000
C17 Malignant neoplasm of small intestine
0.713 0.287 0.000
C23 Malignant neoplasm of gallbladder
0.713 0.287 0.000
C79.6 Secondary malignant neoplasm of ovary
0.712 0.287 0.000
C18.5 Splenic flexure
0.712 0.288 0.000
Q80-Q89 Other congenital malformations
0.712 0.288 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.711 0.289 0.000
N35 Urethral stricture
0.711 0.289 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.710 0.290 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.710 0.290 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.710 0.290 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.710 0.290 0.000
J86.9 Pyothorax without fistula
0.710 0.290 0.000
M25.3 Other instability of joint
0.709 0.291 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.709 0.291 0.000
M54.56 Low back pain (Lumbar region)
0.708 0.292 0.000
Y40.0 Penicillins
0.708 0.292 0.000
N37 Urethral disorders in diseases classified elsewhere
0.708 0.292 0.000
N33 Bladder disorders in diseases classified elsewhere
0.708 0.292 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.708 0.292 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.707 0.293 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.707 0.293 0.000
N32.4 Rupture of bladder, nontraumatic
0.707 0.293 0.000
N32.2 Vesical fistula, not elsewhere classified
0.707 0.293 0.000
M53 Other dorsopathies, not elsewhere classified
0.707 0.293 0.000
N02 Recurrent and persistent haematuria
0.707 0.293 0.000
J98.9 Respiratory disorder, unspecified
0.705 0.295 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.705 0.295 0.000
C95 Leukaemia of unspecified cell type
0.705 0.295 0.000
C94 Other leukaemias of specified cell type
0.705 0.295 0.000
C93 Monocytic leukaemia
0.705 0.295 0.000
C86 Other specified types of T/NK-cell lymphoma
0.705 0.295 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.705 0.295 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.705 0.295 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.704 0.296 0.000
C80 Malignant neoplasm without specification of site
0.704 0.296 0.000
C18.1 Appendix
0.703 0.297 0.000
X60-X84 Intentional self-harm
0.703 0.297 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.701 0.299 0.000
J81 Pulmonary oedema
0.701 0.299 0.000
Y95 Nosocomial condition
0.699 0.301 0.000
M21.0 Valgus deformity, not elsewhere classified
0.699 0.301 0.000
M79.2 Neuralgia and neuritis, unspecified
0.698 0.302 0.000
D67 Hereditary factor IX deficiency
0.698 0.302 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.698 0.302 0.000
J33.0 Polyp of nasal cavity
0.698 0.302 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.698 0.302 0.000
O26.8 Other specified pregnancy-related conditions
0.697 0.303 0.000
D55-D59 Haemolytic anaemias
0.696 0.304 0.000
D68.4 Acquired coagulation factor deficiency
0.696 0.304 0.000
D68.1 Hereditary factor XI deficiency
0.696 0.304 0.000
C18.3 Hepatic flexure
0.695 0.304 0.000
M76 Enthesopathies of lower limb, excluding foot
0.695 0.305 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.695 0.305 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.695 0.305 0.000
M33 Dermatopolymyositis
0.695 0.305 0.000
M32 Systemic lupus erythematosus
0.695 0.305 0.000
C81 Hodgkin's disease
0.694 0.306 0.000
M79.63 Pain in limb (Forearm)
0.694 0.306 0.000
M25.76 Osteophyte (Lower leg)
0.694 0.306 0.000
J96 Respiratory failure, not elsewhere classified
0.694 0.306 0.000
A41 Other septicaemia
0.694 0.306 0.000
M25.78 Osteophyte (Other)
0.694 0.306 0.000
M22.2 Patellofemoral disorders
0.693 0.306 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.693 0.307 0.000
Y35-Y36 Legal intervention and operations of war
0.693 0.307 0.000
Y10-Y34 Event of undetermined intent
0.693 0.307 0.000
X85-X99 Assault
0.693 0.307 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.693 0.307 0.000
X30-X39 Exposure to forces of nature
0.693 0.307 0.000
X20-X29 Contact with venomous animals and plants
0.693 0.307 0.000
X10-X19 Contact with heat and hot substances
0.693 0.307 0.000
X00-X09 Exposure to smoke, fire and flames
0.693 0.307 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.693 0.307 0.000
W75-W84 Other accidental threats to breathing
0.693 0.307 0.000
W65-W74 Accidental drowning and submersion
0.693 0.307 0.000
W50-W64 Exposure to animate mechanical forces
0.693 0.307 0.000
V98-V99 Other and unspecified transport accidents
0.693 0.307 0.000
V95-V97 Air and space transport accidents
0.693 0.307 0.000
V90-V94 Water transport accidents
0.693 0.307 0.000
V80-V89 Other land transport accidents
0.693 0.307 0.000
V70-V79 Bus occupant injured in transport accident
0.693 0.307 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.693 0.307 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.693 0.307 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.693 0.307 0.000
V01-V09 Pedestrian injured in transport accident
0.693 0.307 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.692 0.308 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.691 0.309 0.000
C18.6 Descending colon
0.691 0.309 0.000
X50-X57 Overexertion, travel and privation
0.690 0.309 0.000
D04 Carcinoma in situ of skin
0.690 0.310 0.000
Y84.2 Radiological procedure and radiotherapy
0.690 0.310 0.000
J32.4 Chronic pansinusitis
0.690 0.310 0.000
M79.9 Soft tissue disorder, unspecified
0.689 0.311 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.689 0.311 0.000
M79.3 Panniculitis, unspecified
0.689 0.311 0.000
M50.2 Other cervical disk displacement
0.687 0.313 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.686 0.314 0.000
C91.4 Hairy-cell leukaemia
0.685 0.314 0.000
C91.0 Acute lymphoblastic leukaemia
0.685 0.315 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.685 0.315 0.000
M25.77 Osteophyte (Ankle and foot)
0.685 0.315 0.000
M62 Other disorders of muscle
0.683 0.317 0.000
M51.3 Other specified intervertebral disk degeneration
0.683 0.317 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.683 0.317 0.000
M51.4 Schmorl's nodes
0.683 0.317 0.000
J84 Other interstitial pulmonary diseases
0.683 0.317 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.683 0.317 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.682 0.318 0.000
J98.3 Compensatory emphysema
0.682 0.318 0.000
J98.2 Interstitial emphysema
0.682 0.318 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.681 0.319 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.681 0.319 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.681 0.319 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.681 0.319 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.681 0.319 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.680 0.320 0.000
C67.9 Bladder, unspecified
0.680 0.320 0.000
M22.8 Other disorders of patella
0.679 0.321 0.000
S00.8 Superficial injury of other parts of head
0.679 0.321 0.000
Q21 Congenital malformations of cardiac septa
0.679 0.321 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.678 0.321 0.000
W18 Other fall on same level
0.677 0.322 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.677 0.323 0.000
C18.8 Overlapping lesion of colon
0.676 0.324 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.675 0.325 0.000
M79.7 Fibromyalgia
0.675 0.325 0.000
D06 Carcinoma in situ of cervix uteri
0.674 0.326 0.000
D43.2 Brain, unspecified
0.674 0.326 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.674 0.326 0.000
Q35-Q37 Cleft lip and cleft palate
0.674 0.326 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.674 0.326 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.674 0.326 0.000
C25.0 Head of pancreas
0.674 0.326 0.000
M79.88 Other specified soft tissue disorders (Other)
0.674 0.326 0.000
N62 Hypertrophy of breast
0.674 0.326 0.000
N63 Unspecified lump in breast
0.672 0.328 0.000
Q60-Q64 Congenital malformations of the urinary system
0.672 0.328 0.000
C18.4 Transverse colon
0.671 0.329 0.000
M72 Fibroblastic disorders
0.669 0.331 0.000
C90.3 Solitary plasmacytoma
0.669 0.331 0.000
C90.1 Plasma cell leukaemia
0.669 0.331 0.000
H80-H83 Diseases of inner ear
0.668 0.332 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.668 0.332 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.667 0.333 0.000
O20 Haemorrhage in early pregnancy
0.666 0.333 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.666 0.334 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.666 0.334 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.665 0.335 0.000
M86-M90 Other osteopathies
0.664 0.335 0.000
L50-L54 Urticaria and erythema
0.664 0.336 0.000
O21 Excessive vomiting in pregnancy
0.662 0.338 0.000
S70-S79 Injuries to the hip and thigh
0.662 0.338 0.000
N05 Unspecified nephritic syndrome
0.661 0.339 0.000
J37.0 Chronic laryngitis
0.661 0.339 0.000
M05 Seropositive rheumatoid arthritis
0.660 0.340 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.660 0.340 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.660 0.340 0.000
C34 Malignant neoplasm of bronchus and lung
0.660 0.340 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.659 0.341 0.000
D09.0 Bladder
0.659 0.341 0.000
C65 Malignant neoplasm of renal pelvis
0.659 0.341 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.659 0.341 0.000
S20-S29 Injuries to the thorax
0.658 0.342 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.658 0.342 0.000
M79.68 Pain in limb (Other)
0.658 0.342 0.000
M79.61 Pain in limb (Shoulder region)
0.658 0.342 0.000
M30.0 Polyarteritis nodosa
0.658 0.342 0.000
C92.1 Chronic myeloid leukaemia
0.657 0.342 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.657 0.342 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.657 0.343 0.000
W07 Fall involving chair
0.657 0.343 0.000
M60 Myositis
0.656 0.343 0.000
D68.0 Von Willebrand's disease
0.655 0.345 0.000
M25.2 Flail joint
0.655 0.345 0.000
M25.1 Fistula of joint
0.655 0.345 0.000
S00.0 Superficial injury of scalp
0.654 0.346 0.000
N10-N16 Renal tubulo-interstitial diseases
0.654 0.346 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.654 0.346 0.000
C16.9 Stomach, unspecified
0.654 0.346 0.000
C15.8 Overlapping lesion of oesophagus
0.652 0.347 0.000
C15.3 Upper third of oesophagus
0.652 0.347 0.000
C15.2 Abdominal part of oesophagus
0.652 0.347 0.000
C15.1 Thoracic part of oesophagus
0.652 0.347 0.000
C15.0 Cervical part of oesophagus
0.652 0.347 0.000
M41 Scoliosis
0.652 0.348 0.000
M07 Psoriatic and enteropathic arthropathies
0.652 0.348 0.000
L27 Dermatitis due to substances taken internally
0.652 0.348 0.000
M25.8 Other specified joint disorders
0.651 0.349 0.000
C91.9 Lymphoid leukaemia, unspecified
0.648 0.352 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.648 0.352 0.000
C91.7 Other lymphoid leukaemia
0.648 0.352 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.648 0.352 0.000
C91.5 Adult T-cell leukaemia
0.648 0.352 0.000
C91.3 Prolymphocytic leukaemia
0.648 0.352 0.000
C91.2 Subacute lymphocytic leukaemia
0.648 0.352 0.000
M25.0 Haemarthrosis
0.648 0.352 0.000
O60-O75 Complications of labour and delivery
0.647 0.353 0.000
O29 Complications of anaesthesia during pregnancy
0.647 0.353 0.000
O28 Abnormal findings on antenatal screening of mother
0.647 0.353 0.000
O22 Venous complications in pregnancy
0.647 0.353 0.000
O25 Malnutrition in pregnancy
0.647 0.353 0.000
O23 Infections of genito-urinary tract in pregnancy
0.646 0.354 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.646 0.354 0.000
C77.1 Intrathoracic lymph nodes
0.645 0.355 0.000
M14 Arthropathies in other diseases classified elsewhere
0.645 0.355 0.000
M12 Other specific arthropathies
0.645 0.355 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.645 0.355 0.000
M08 Juvenile arthritis
0.645 0.355 0.000
D47.2 Monoclonal gammopathy
0.645 0.355 0.000
J31.0 Chronic rhinitis
0.644 0.356 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.644 0.356 0.000
J80 Adult respiratory distress syndrome
0.644 0.356 0.000
N17.0 Acute renal failure with tubular necrosis
0.644 0.356 0.000
M06.3 Rheumatoid nodule
0.643 0.357 0.000
C15.5 Lower third of oesophagus
0.643 0.357 0.000
M25.5 Pain in joint
0.642 0.358 0.000
M11 Other crystal arthropathies
0.642 0.358 0.000
M21.3 Wrist or foot drop (acquired)
0.641 0.359 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.641 0.359 0.000
N27 Small kidney of unknown cause
0.641 0.359 0.000
N25 Disorders resulting from impaired renal tubular function
0.641 0.359 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.640 0.360 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.640 0.360 0.000
N64 Other disorders of breast
0.640 0.360 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.639 0.360 0.000
J60-J70 Lung diseases due to external agents
0.639 0.361 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.639 0.361 0.000
N02.8 Other
0.639 0.361 0.000
H65-H75 Diseases of middle ear and mastoid
0.639 0.361 0.000
N32.1 Vesicointestinal fistula
0.638 0.362 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.638 0.362 0.000
M79.16 Myalgia (Lower leg)
0.637 0.363 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.636 0.364 0.000
M22.1 Recurrent subluxation of patella
0.636 0.364 0.000
M22.9 Disorder of patella, unspecified
0.636 0.364 0.000
M22.3 Other derangements of patella
0.636 0.364 0.000
M22.0 Recurrent dislocation of patella
0.636 0.364 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.635 0.364 0.000
J98.8 Other specified respiratory disorders
0.635 0.365 0.000
T00-T07 Injuries involving multiple body regions
0.634 0.366 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.633 0.366 0.000
C66 Malignant neoplasm of ureter
0.633 0.366 0.000
M31 Other necrotising vasculopathies
0.633 0.367 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.633 0.367 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.633 0.367 0.000
C32.9 Larynx, unspecified
0.633 0.367 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.632 0.367 0.000
D80-D89 Certain disorders involving the immune mechanism
0.632 0.367 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.632 0.368 0.000
D37.1 Stomach
0.632 0.368 0.000
M21.9 Acquired deformity of limb, unspecified
0.631 0.368 0.000
M21.8 Other specified acquired deformities of limbs
0.631 0.368 0.000
M21.7 Unequal limb length (acquired)
0.631 0.368 0.000
M21.4 Flat foot [pes planus] (acquired)
0.631 0.368 0.000
M21.2 Flexion deformity
0.631 0.368 0.000
M66 Spontaneous rupture of synovium and tendon
0.631 0.369 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.631 0.369 0.000
J32.0 Chronic maxillary sinusitis
0.630 0.370 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.630 0.370 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.630 0.370 0.000
D48.7 Other specified sites
0.629 0.371 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.629 0.371 0.000
J32.3 Chronic sphenoidal sinusitis
0.628 0.372 0.000
J32.1 Chronic frontal sinusitis
0.628 0.372 0.000
M06.8 Other specified rheumatoid arthritis
0.628 0.372 0.000
M06.4 Inflammatory polyarthropathy
0.628 0.372 0.000
M06.2 Rheumatoid bursitis
0.628 0.372 0.000
M06.1 Adult-onset Still's disease
0.628 0.372 0.000
M80 Osteoporosis with pathological fracture
0.627 0.372 0.000
M25.4 Effusion of joint
0.625 0.374 0.000
N36 Other disorders of urethra
0.625 0.375 0.000
M21.6 Other acquired deformities of ankle and foot
0.625 0.375 0.000
M71 Other bursopathies
0.624 0.376 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.624 0.376 0.000
C77.8 Lymph nodes of multiple regions
0.623 0.377 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.623 0.377 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.623 0.377 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.623 0.377 0.000
C31 Malignant neoplasm of accessory sinuses
0.623 0.377 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.623 0.377 0.000
C37 Malignant neoplasm of thymus
0.623 0.377 0.000
C33 Malignant neoplasm of trachea
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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