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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117206795
log Bayes Factor = 31.2014
Chromosome 15   position 67,270,650  (GRCh37) Explore rs117206795 on Ensembl!
Variant rs117206795 is part of Cluster X0212

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Z86 Personal history of certain other diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
K80 Cholelithiasis
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.998 0.002 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.998 0.002 0.000
E78.0 Pure hypercholesterolaemia
0.998 0.002 0.000
M54 Dorsalgia
0.994 0.006 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.991 0.009 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.990 0.010 0.000
M70-M79 Other soft tissue disorders
0.987 0.013 0.000
I10-I15 Hypertensive diseases
0.985 0.015 0.000
I34 Nonrheumatic mitral valve disorders
0.985 0.015 0.000
M54.9 Dorsalgia, unspecified
0.978 0.022 0.000
R13 Dysphagia
0.977 0.023 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.976 0.024 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.973 0.027 0.000
M51 Other intervertebral disk disorders
0.969 0.031 0.000
M05-M14 Inflammatory polyarthropathies
0.967 0.033 0.000
I34.0 Mitral (valve) insufficiency
0.966 0.034 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.962 0.038 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.962 0.038 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.959 0.041 0.000
N17-N19 Renal failure
0.959 0.041 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.956 0.044 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.954 0.046 0.000
R05 Cough
0.951 0.049 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.950 0.050 0.000
Z86.4 Personal history of psychoactive substance abuse
0.947 0.053 0.000
Chapter X Diseases of the respiratory system
0.946 0.054 0.000
Chapter I Certain infectious and parasitic diseases
0.946 0.054 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.945 0.055 0.000
K40-K46 Hernia
0.945 0.055 0.000
I10 Essential (primary) hypertension
0.945 0.055 0.000
I51 Complications and ill-defined descriptions of heart disease
0.942 0.058 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.941 0.059 0.000
R12 Heartburn
0.941 0.059 0.000
Z87 Personal history of other diseases and conditions
0.941 0.059 0.000
R50-R69 General symptoms and signs
0.937 0.063 0.000
M79.8 Other specified soft tissue disorders
0.936 0.064 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.935 0.065 0.000
M80-M85 Disorders of bone density and structure
0.934 0.066 0.000
K20 Oesophagitis
0.923 0.077 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.923 0.077 0.000
E20-E35 Disorders of other endocrine glands
0.921 0.079 0.000
M13 Other arthritis
0.920 0.080 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.919 0.081 0.000
M54.5 Low back pain
0.918 0.082 0.000
M51.2 Other specified intervertebral disk displacement
0.916 0.084 0.000
Chapter XX External causes of morbidity and mortality
0.915 0.085 0.000
I35 Nonrheumatic aortic valve disorders
0.915 0.085 0.000
S90-S99 Injuries to the ankle and foot
0.913 0.087 0.000
I50 Heart failure
0.913 0.087 0.000
Z86.7 Personal history of diseases of the circulatory system
0.910 0.090 0.000
S60-S69 Injuries to the wrist and hand
0.910 0.090 0.000
N30-N39 Other diseases of urinary system
0.909 0.091 0.000
K26 Duodenal ulcer
0.908 0.092 0.000
S80-S89 Injuries to the knee and lower leg
0.908 0.092 0.000
J95-J99 Other diseases of the respiratory system
0.905 0.095 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.905 0.095 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.904 0.096 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.900 0.100 0.000
N40-N51 Diseases of male genital organs
0.899 0.101 0.000
Z95.0 Presence of cardiac pacemaker
0.898 0.102 0.000
S20-S29 Injuries to the thorax
0.898 0.102 0.000
I51.8 Other ill-defined heart diseases
0.897 0.103 0.000
I12 Hypertensive renal disease
0.896 0.104 0.000
N40 Hyperplasia of prostate
0.894 0.106 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.894 0.106 0.000
Z87.1 Personal history of diseases of the digestive system
0.894 0.106 0.000
N19 Unspecified renal failure
0.890 0.110 0.000
I45 Other conduction disorders
0.887 0.113 0.000
M81 Osteoporosis without pathological fracture
0.887 0.113 0.000
M13.9 Arthritis, unspecified
0.886 0.114 0.000
R10 Abdominal and pelvic pain
0.886 0.114 0.000
N18 Chronic renal failure
0.883 0.117 0.000
R09.1 Pleurisy
0.880 0.120 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.880 0.120 0.000
K43 Ventral hernia
0.880 0.120 0.000
J98 Other respiratory disorders
0.878 0.122 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.874 0.126 0.000
N00-N08 Glomerular diseases
0.872 0.128 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.869 0.131 0.000
E83 Disorders of mineral metabolism
0.867 0.133 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.867 0.133 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.865 0.135 0.000
I60-I69 Cerebrovascular diseases
0.864 0.136 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.864 0.136 0.000
R53 Malaise and fatigue
0.863 0.137 0.000
R17 Unspecified jaundice
0.863 0.137 0.000
Chapter II Neoplasms
0.863 0.137 0.000
K31 Other diseases of stomach and duodenum
0.862 0.138 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.860 0.140 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.858 0.142 0.000
R63 Symptoms and signs concerning food and fluid intake
0.855 0.145 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.855 0.145 0.000
M81.9 Osteoporosis, unspecified
0.853 0.147 0.000
Z80 Family history of malignant neoplasm
0.852 0.148 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.852 0.148 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.850 0.150 0.000
E88 Other metabolic disorders
0.850 0.150 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.850 0.150 0.000
J40-J47 Chronic lower respiratory diseases
0.849 0.151 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.846 0.154 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.845 0.155 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.845 0.155 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.844 0.156 0.000
M06 Other rheumatoid arthritis
0.843 0.156 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.842 0.158 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.839 0.161 0.000
K35-K38 Diseases of appendix
0.838 0.162 0.000
I34.1 Mitral (valve) prolapse
0.837 0.163 0.000
R10.3 Pain localised to other parts of lower abdomen
0.837 0.163 0.000
N39 Other disorders of urinary system
0.835 0.165 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.834 0.166 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.833 0.167 0.000
Z02 Examination and encounter for administrative purposes
0.833 0.167 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.833 0.167 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.832 0.168 0.000
I12.0 Hypertensive renal disease with renal failure
0.832 0.168 0.000
I05-I09 Chronic rheumatic heart diseases
0.831 0.168 0.000
N93 Other abnormal uterine and vaginal bleeding
0.831 0.169 0.000
B35-B49 Mycoses
0.829 0.171 0.000
S92 Fracture of foot, except ankle
0.828 0.172 0.000
E65-E68 Obesity and other hyperalimentation
0.827 0.173 0.000
K70-K77 Diseases of liver
0.826 0.174 0.000
M51.9 Intervertebral disk disorder, unspecified
0.824 0.176 0.000
R11 Nausea and vomiting
0.824 0.176 0.000
Z83 Family history of other specific disorders
0.823 0.177 0.000
N92 Excessive, frequent and irregular menstruation
0.822 0.178 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.822 0.178 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.820 0.179 0.000
J98.1 Pulmonary collapse
0.820 0.180 0.000
K25 Gastric ulcer
0.818 0.182 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.818 0.182 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.818 0.182 0.000
I47 Paroxysmal tachycardia
0.818 0.182 0.000
N10-N16 Renal tubulo-interstitial diseases
0.817 0.183 0.000
I73 Other peripheral vascular diseases
0.816 0.184 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.814 0.186 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.813 0.187 0.000
N39.0 Urinary tract infection, site not specified
0.812 0.188 0.000
Chapter XXII Codes for special purposes
0.809 0.190 0.000
I50.9 Heart failure, unspecified
0.809 0.191 0.000
M79.7 Fibromyalgia
0.809 0.191 0.000
K42 Umbilical hernia
0.808 0.192 0.000
J00-J06 Acute upper respiratory infections
0.807 0.192 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.807 0.193 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.807 0.193 0.000
N18.9 Chronic renal failure, unspecified
0.801 0.199 0.000
M54.56 Low back pain (Lumbar region)
0.799 0.201 0.000
K80.4 Calculus of bile duct with cholecystitis
0.798 0.202 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.798 0.202 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.798 0.202 0.000
Z04 Examination and observation for other reasons
0.797 0.203 0.000
I51.7 Cardiomegaly
0.797 0.203 0.000
M72 Fibroblastic disorders
0.796 0.204 0.000
R07 Pain in throat and chest
0.796 0.204 0.000
I35.1 Aortic (valve) insufficiency
0.796 0.204 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.793 0.207 0.000
I44 Atrioventricular and left bundle-branch block
0.792 0.208 0.000
N45 Orchitis and epididymitis
0.792 0.208 0.000
C64-C68 Malignant neoplasms of urinary tract
0.791 0.209 0.000
Chapter V Mental and behavioural disorders
0.789 0.211 0.000
Z95.4 Presence of other heart-valve replacement
0.789 0.211 0.000
Z00.0 General medical examination
0.788 0.212 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.788 0.212 0.000
N18.4 Chronic kidney disease, stage 4
0.787 0.213 0.000
I38 Endocarditis, valve unspecified
0.785 0.215 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.785 0.215 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.784 0.216 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.784 0.216 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.783 0.216 0.000
R16.1 Splenomegaly, not elsewhere classified
0.783 0.217 0.000
R06 Abnormalities of breathing
0.783 0.217 0.000
R54 Senility
0.782 0.218 0.000
S80 Superficial injury of lower leg
0.781 0.219 0.000
Z95.2 Presence of prosthetic heart valve
0.781 0.219 0.000
I42 Cardiomyopathy
0.780 0.220 0.000
T66-T78 Other and unspecified effects of external causes
0.780 0.220 0.000
S32 Fracture of lumbar spine and pelvis
0.777 0.223 0.000
K86 Other diseases of pancreas
0.775 0.225 0.000
M75 Shoulder lesions
0.774 0.226 0.000
R63.4 Abnormal weight loss
0.774 0.226 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.773 0.227 0.000
Z82.3 Family history of stroke
0.773 0.227 0.000
A30-A49 Other bacterial diseases
0.773 0.227 0.000
R41.0 Disorientation, unspecified
0.772 0.228 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.771 0.229 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.769 0.231 0.000
I49 Other cardiac arrhythmias
0.766 0.234 0.000
Chapter VI Diseases of the nervous system
0.766 0.234 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.765 0.235 0.000
J43 Emphysema
0.765 0.235 0.000
K83 Other diseases of biliary tract
0.765 0.235 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.764 0.236 0.000
M54.59 Low back pain (Site unspecified)
0.764 0.236 0.000
S68 Traumatic amputation of wrist and hand
0.763 0.237 0.000
I11 Hypertensive heart disease
0.763 0.237 0.000
S81 Open wound of lower leg
0.763 0.237 0.000
M40-M43 Deforming dorsopathies
0.762 0.237 0.000
M71 Other bursopathies
0.762 0.238 0.000
K26.7 Chronic without haemorrhage or perforation
0.762 0.238 0.000
M54.2 Cervicalgia
0.761 0.238 0.000
Z94 Transplanted organ and tissue status
0.761 0.239 0.000
M13.98 Arthritis, unspecified (Other)
0.759 0.241 0.000
S10-S19 Injuries to the neck
0.758 0.242 0.000
Z83.7 Family history of diseases of the digestive system
0.757 0.243 0.000
K31.8 Other specified diseases of stomach and duodenum
0.756 0.244 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.755 0.245 0.000
M06.9 Rheumatoid arthritis, unspecified
0.755 0.245 0.000
E28 Ovarian dysfunction
0.754 0.246 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.753 0.247 0.000
C67 Malignant neoplasm of bladder
0.753 0.247 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.753 0.247 0.000
R40 Somnolence, stupor and coma
0.752 0.247 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.751 0.249 0.000
I45.1 Other and unspecified right bundle-branch block
0.751 0.249 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.750 0.250 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.749 0.251 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.748 0.252 0.000
E83.4 Disorders of magnesium metabolism
0.748 0.252 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.748 0.252 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.747 0.253 0.000
K82 Other diseases of gallbladder
0.746 0.254 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.746 0.254 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.745 0.254 0.000
T42.4 Benzodiazepines
0.745 0.255 0.000
B37 Candidiasis
0.745 0.255 0.000
M79.1 Myalgia
0.744 0.255 0.000
A80-A89 Viral infections of the central nervous system
0.744 0.256 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.743 0.257 0.000
Z29 Need for other prophylactic measures
0.743 0.257 0.000
E29 Testicular dysfunction
0.742 0.258 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.742 0.258 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.741 0.259 0.000
K85 Acute pancreatitis
0.740 0.260 0.000
R51 Headache
0.740 0.260 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.739 0.260 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.739 0.261 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.739 0.261 0.000
K40 Inguinal hernia
0.738 0.262 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.736 0.264 0.000
Z87.0 Personal history of diseases of the respiratory system
0.736 0.264 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.735 0.264 0.000
M13.94 Arthritis, unspecified (Hand)
0.735 0.265 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.735 0.265 0.000
R10.1 Pain localised to upper abdomen
0.735 0.265 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.734 0.266 0.000
R25 Abnormal involuntary movements
0.734 0.266 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.734 0.266 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.733 0.267 0.000
B95-B98 Bacterial, viral and other infectious agents
0.733 0.267 0.000
Z02.8 Other examinations for administrative purposes
0.733 0.267 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.733 0.267 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.733 0.267 0.000
S50-S59 Injuries to the elbow and forearm
0.733 0.267 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.731 0.269 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.731 0.269 0.000
M51.8 Other specified intervertebral disk disorders
0.730 0.270 0.000
M54.3 Sciatica
0.730 0.270 0.000
S69 Other and unspecified injuries of wrist and hand
0.730 0.270 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.730 0.270 0.000
M86-M90 Other osteopathies
0.729 0.271 0.000
M75.0 Adhesive capsulitis of shoulder
0.729 0.271 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.728 0.272 0.000
N18.2 Chronic kidney disease, stage 2
0.728 0.272 0.000
I45.5 Other specified heart block
0.728 0.272 0.000
R07.0 Pain in throat
0.727 0.273 0.000
N92.3 Ovulation bleeding
0.727 0.273 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.727 0.273 0.000
K46 Unspecified abdominal hernia
0.726 0.274 0.000
M50 Cervical disk disorders
0.726 0.274 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.724 0.276 0.000
R44.0 Auditory hallucinations
0.724 0.276 0.000
M05 Seropositive rheumatoid arthritis
0.724 0.276 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.723 0.276 0.000
K65-K67 Diseases of peritoneum
0.723 0.277 0.000
I73.0 Raynaud's syndrome
0.723 0.277 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.721 0.279 0.000
T79-T79 Certain early complications of trauma
0.720 0.280 0.000
I67 Other cerebrovascular diseases
0.719 0.281 0.000
M54.50 Low back pain (Multiple sites in spine)
0.719 0.281 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.718 0.282 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.718 0.282 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.718 0.282 0.000
I08 Multiple valve diseases
0.718 0.282 0.000
S92.3 Fracture of metatarsal bone
0.717 0.282 0.000
Z93 Artificial opening status
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Chapter VIII Diseases of the ear and mastoid process
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.717 0.283 0.000
M53 Other dorsopathies, not elsewhere classified
0.716 0.283 0.000
K80.3 Calculus of bile duct with cholangitis
0.716 0.283 0.000
K80.8 Other cholelithiasis
0.716 0.283 0.000
M79.5 Residual foreign body in soft tissue
0.716 0.284 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
R07.2 Precordial pain
0.716 0.284 0.000
R47-R49 Symptoms and signs involving speech and voice
0.716 0.284 0.000
S82 Fracture of lower leg, including ankle
0.716 0.284 0.000
I95 Hypotension
0.716 0.284 0.000
E78.8 Other disorders of lipoprotein metabolism
0.715 0.284 0.000
E78.6 Lipoprotein deficiency
0.715 0.284 0.000
E78.4 Other hyperlipidaemia
0.715 0.284 0.000
E78.3 Hyperchylomicronaemia
0.715 0.284 0.000
E78.2 Mixed hyperlipidaemia
0.715 0.284 0.000
E78.1 Pure hyperglyceridaemia
0.715 0.284 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.715 0.285 0.000
S70-S79 Injuries to the hip and thigh
0.715 0.285 0.000
S90 Superficial injury of ankle and foot
0.715 0.285 0.000
M77 Other enthesopathies
0.715 0.285 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.714 0.286 0.000
M07 Psoriatic and enteropathic arthropathies
0.714 0.286 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.713 0.287 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.713 0.287 0.000
M54.8 Other dorsalgia
0.713 0.287 0.000
M54.6 Pain in thoracic spine
0.713 0.287 0.000
M54.4 Lumbago with sciatica
0.713 0.287 0.000
M54.0 Panniculitis affecting regions of neck and back
0.713 0.287 0.000
I50.0 Congestive heart failure
0.713 0.287 0.000
I35.0 Aortic (valve) stenosis
0.712 0.288 0.000
M79.0 Rheumatism, unspecified
0.712 0.288 0.000
I50.1 Left ventricular failure
0.712 0.288 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.711 0.289 0.000
E27 Other disorders of adrenal gland
0.711 0.289 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.711 0.289 0.000
I47.1 Supraventricular tachycardia
0.710 0.290 0.000
R45 Symptoms and signs involving emotional state
0.709 0.291 0.000
R04 Haemorrhage from respiratory passages
0.708 0.292 0.000
M76 Enthesopathies of lower limb, excluding foot
0.708 0.292 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.708 0.292 0.000
S64 Injury of nerves at wrist and hand level
0.707 0.293 0.000
I15 Secondary hypertension
0.707 0.293 0.000
I13 Hypertensive heart and renal disease
0.707 0.293 0.000
R15 Faecal incontinence
0.707 0.293 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.706 0.294 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.706 0.294 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.706 0.294 0.000
E83.1 Disorders of iron metabolism
0.706 0.294 0.000
N02 Recurrent and persistent haematuria
0.705 0.295 0.000
T43.2 Other and unspecified antidepressants
0.705 0.295 0.000
J43.9 Emphysema, unspecified
0.705 0.295 0.000
M54.1 Radiculopathy
0.704 0.295 0.000
Z97 Presence of other devices
0.704 0.296 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.703 0.297 0.000
D45 Polycythaemia vera
0.702 0.298 0.000
R52 Pain, not elsewhere classified
0.702 0.298 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.702 0.298 0.000
N92.6 Irregular menstruation, unspecified
0.701 0.299 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.701 0.299 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.701 0.299 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.701 0.299 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.701 0.299 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.701 0.299 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.701 0.299 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.701 0.299 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.701 0.299 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.701 0.299 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.700 0.300 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.700 0.300 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.700 0.300 0.000
M79.79 Fibromyalgia (Site unspecified)
0.699 0.301 0.000
S92.0 Fracture of calcaneus
0.699 0.301 0.000
S40-S49 Injuries to the shoulder and upper arm
0.698 0.302 0.000
Z10 Routine general health check-up of defined subpopulation
0.698 0.302 0.000
J42 Unspecified chronic bronchitis
0.697 0.303 0.000
M51.3 Other specified intervertebral disk degeneration
0.695 0.305 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.695 0.305 0.000
M51.4 Schmorl's nodes
0.695 0.305 0.000
S20 Superficial injury of thorax
0.695 0.305 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.694 0.306 0.000
Z33 Pregnant state, incidental
0.694 0.306 0.000
M14 Arthropathies in other diseases classified elsewhere
0.694 0.306 0.000
M12 Other specific arthropathies
0.694 0.306 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.694 0.306 0.000
M08 Juvenile arthritis
0.694 0.306 0.000
I69 Sequelae of cerebrovascular disease
0.694 0.306 0.000
N87 Dysplasia of cervix uteri
0.693 0.306 0.000
J98.4 Other disorders of lung
0.693 0.307 0.000
S27 Injury of other and unspecified intrathoracic organs
0.692 0.308 0.000
T92 Sequelae of injuries of upper limb
0.692 0.308 0.000
I77 Other disorders of arteries and arterioles
0.691 0.309 0.000
R41.3 Other amnesia
0.691 0.309 0.000
N36 Other disorders of urethra
0.691 0.309 0.000
R94 Abnormal results of function studies
0.691 0.309 0.000
N32 Other disorders of bladder
0.691 0.309 0.000
M11 Other crystal arthropathies
0.690 0.310 0.000
M79.9 Soft tissue disorder, unspecified
0.690 0.310 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.690 0.310 0.000
M79.3 Panniculitis, unspecified
0.690 0.310 0.000
M79.2 Neuralgia and neuritis, unspecified
0.690 0.310 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.690 0.310 0.000
M65-M68 Disorders of synovium and tendon
0.690 0.310 0.000
R80 Isolated proteinuria
0.690 0.310 0.000
N03 Chronic nephritic syndrome
0.690 0.310 0.000
N86 Erosion and ectropion of cervix uteri
0.690 0.310 0.000
K74 Fibrosis and cirrhosis of liver
0.690 0.310 0.000
J30-J39 Other diseases of upper respiratory tract
0.689 0.311 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.689 0.311 0.000
R81 Glycosuria
0.688 0.312 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.688 0.312 0.000
I74 Arterial embolism and thrombosis
0.688 0.312 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.686 0.314 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.686 0.314 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.686 0.314 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.686 0.314 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.686 0.314 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.686 0.314 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.686 0.314 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.686 0.314 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.686 0.314 0.000
T36 Poisoning by systemic antibiotics
0.686 0.314 0.000
K28 Gastrojejunal ulcer
0.684 0.316 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.684 0.316 0.000
R56 Convulsions, not elsewhere classified
0.683 0.317 0.000
R63.1 Polydipsia
0.683 0.317 0.000
I72 Other aneurysm
0.682 0.318 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.682 0.318 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.681 0.319 0.000
Y86 Sequelae of other accidents
0.681 0.319 0.000
Z04.8 Examination and observation for other specified reasons
0.681 0.319 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.681 0.319 0.000
I45.9 Conduction disorder, unspecified
0.681 0.319 0.000
N99-N99 Other disorders of the genitourinary system
0.680 0.320 0.000
J06.9 Acute upper respiratory infection, unspecified
0.679 0.321 0.000
R61 Hyperhidrosis
0.679 0.321 0.000
V10-V19 Pedal cyclist injured in transport accident
0.679 0.321 0.000
I60 Subarachnoid haemorrhage
0.679 0.321 0.000
R50 Fever of unknown origin
0.678 0.322 0.000
I44.2 Atrioventricular block, complete
0.678 0.322 0.000
B99-B99 Other infectious diseases
0.678 0.322 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.678 0.322 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.678 0.322 0.000
B65-B83 Helminthiases
0.678 0.322 0.000
B50-B64 Protozoal diseases
0.678 0.322 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.678 0.322 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.678 0.322 0.000
A75-A79 Rickettsioses
0.678 0.322 0.000
A70-A74 Other diseases caused by chlamydiae
0.678 0.322 0.000
A65-A69 Other spirochaetal diseases
0.678 0.322 0.000
A20-A28 Certain zoonotic bacterial diseases
0.678 0.322 0.000
A15-A19 Tuberculosis
0.678 0.322 0.000
R46 Symptoms and signs involving appearance and behaviour
0.678 0.322 0.000
R43 Disturbances of smell and taste
0.678 0.322 0.000
K45 Other abdominal hernia
0.678 0.322 0.000
B15-B19 Viral hepatitis
0.677 0.323 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.677 0.323 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.677 0.323 0.000
N39.8 Other specified disorders of urinary system
0.676 0.324 0.000
Z36 Antenatal screening
0.676 0.324 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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