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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117242132
log Bayes Factor = 21.0067
Chromosome 18   position 45,672,152  (GRCh37) Explore rs117242132 on Ensembl!
Variant rs117242132 is part of Cluster X0094

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
I50 Heart failure
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
Z51 Other medical care
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
I63 Cerebral infarction
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
Z50 Care involving use of rehabilitation procedures
0.991 0.009 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.991 0.009 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.988 0.012 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.986 0.014 0.000
I50.9 Heart failure, unspecified
0.986 0.014 0.000
I05-I09 Chronic rheumatic heart diseases
0.986 0.014 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.984 0.016 0.000
C50-C50 Malignant neoplasm of breast
0.980 0.020 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.978 0.022 0.000
Chapter VIII Diseases of the ear and mastoid process
0.976 0.024 0.000
Y43 Primarily systemic agents
0.974 0.026 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.969 0.031 0.000
Z51.3 Blood transfusion without reported diagnosis
0.968 0.032 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.966 0.034 0.000
C50 Malignant neoplasm of breast
0.965 0.035 0.000
I67 Other cerebrovascular diseases
0.961 0.039 0.000
J47 Bronchiectasis
0.959 0.041 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.957 0.043 0.000
Y43.3 Other antineoplastic drugs
0.956 0.044 0.000
I63.9 Cerebral infarction, unspecified
0.956 0.044 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.954 0.046 0.000
J40 Bronchitis, not specified as acute or chronic
0.954 0.046 0.000
G90-G99 Other disorders of the nervous system
0.954 0.046 0.000
J44 Other chronic obstructive pulmonary disease
0.951 0.049 0.000
G40-G47 Episodic and paroxysmal disorders
0.950 0.050 0.000
Z51.1 Chemotherapy session for neoplasm
0.948 0.052 0.000
Z50.5 Speech therapy
0.945 0.055 0.000
Z51.5 Palliative care
0.942 0.058 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.941 0.059 0.000
I07 Rheumatic tricuspid valve diseases
0.940 0.060 0.000
H90-H95 Other disorders of ear
0.937 0.063 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.935 0.065 0.000
I49 Other cardiac arrhythmias
0.931 0.069 0.000
I42 Cardiomyopathy
0.929 0.071 0.000
G93 Other disorders of brain
0.929 0.071 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.925 0.075 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.924 0.076 0.000
C79 Secondary malignant neoplasm of other sites
0.922 0.078 0.000
I08 Multiple valve diseases
0.922 0.078 0.000
D80-D89 Certain disorders involving the immune mechanism
0.920 0.080 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.919 0.081 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.918 0.082 0.000
I50.1 Left ventricular failure
0.917 0.083 0.000
Z30 Contraceptive management
0.914 0.086 0.000
J00-J06 Acute upper respiratory infections
0.913 0.087 0.000
C77.5 Intrapelvic lymph nodes
0.912 0.088 0.000
I07.1 Tricuspid insufficiency
0.908 0.092 0.000
Chapter VII Diseases of the eye and adnexa
0.903 0.097 0.000
D70 Agranulocytosis
0.902 0.098 0.000
C77.0 Lymph nodes of head, face and neck
0.900 0.100 0.000
I50.0 Congestive heart failure
0.896 0.104 0.000
Z35 Supervision of high-risk pregnancy
0.894 0.106 0.000
D60-D64 Aplastic and other anaemias
0.892 0.108 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.890 0.110 0.000
S00-S09 Injuries to the head
0.887 0.113 0.000
I51 Complications and ill-defined descriptions of heart disease
0.885 0.115 0.000
Z39 Postpartum care and examination
0.884 0.116 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.884 0.116 0.000
Z45 Adjustment and management of implanted device
0.883 0.117 0.000
J60-J70 Lung diseases due to external agents
0.883 0.117 0.000
R73 Elevated blood glucose level
0.883 0.117 0.000
C50.8 Overlapping lesion of breast
0.882 0.118 0.000
I67.8 Other specified cerebrovascular diseases
0.881 0.119 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.879 0.121 0.000
I27 Other pulmonary heart diseases
0.876 0.124 0.000
I67.9 Cerebrovascular disease, unspecified
0.871 0.129 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.868 0.132 0.000
D86 Sarcoidosis
0.868 0.132 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.867 0.133 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.863 0.137 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.862 0.138 0.000
D73 Diseases of spleen
0.862 0.138 0.000
Z43 Attention to artificial openings
0.861 0.139 0.000
Chapter V Mental and behavioural disorders
0.860 0.140 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.859 0.141 0.000
I49.9 Cardiac arrhythmia, unspecified
0.858 0.142 0.000
I69 Sequelae of cerebrovascular disease
0.856 0.144 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.856 0.144 0.000
I49.3 Ventricular premature depolarisation
0.856 0.144 0.000
R73.9 Hyperglycaemia, unspecified
0.856 0.144 0.000
M86-M90 Other osteopathies
0.855 0.145 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.854 0.146 0.000
H91 Other hearing loss
0.854 0.146 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.852 0.148 0.000
G43 Migraine
0.851 0.149 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.851 0.149 0.000
I45 Other conduction disorders
0.848 0.152 0.000
Z50.1 Other physical therapy
0.847 0.153 0.000
I38 Endocarditis, valve unspecified
0.844 0.156 0.000
G30-G32 Other degenerative diseases of the nervous system
0.843 0.157 0.000
Chapter XIV Diseases of the genitourinary system
0.842 0.158 0.000
D64 Other anaemias
0.841 0.159 0.000
C50.3 Lower-inner quadrant of breast
0.841 0.159 0.000
I42.9 Cardiomyopathy, unspecified
0.841 0.159 0.000
M60-M63 Disorders of muscles
0.841 0.159 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.840 0.160 0.000
Y43.0 Antiallergic and antiemetic drugs
0.839 0.161 0.000
H43-H45 Disorders of vitreous body and globe
0.839 0.161 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.837 0.163 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.836 0.164 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.835 0.164 0.000
H60-H62 Diseases of external ear
0.835 0.165 0.000
I47 Paroxysmal tachycardia
0.834 0.166 0.000
I42.0 Dilated cardiomyopathy
0.834 0.166 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.834 0.166 0.000
G93.0 Cerebral cysts
0.832 0.168 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.832 0.168 0.000
C77.3 Axillary and upper limb lymph nodes
0.832 0.168 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.831 0.169 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.830 0.170 0.000
I63.8 Other cerebral infarction
0.826 0.174 0.000
Z50.2 Alcohol rehabilitation
0.824 0.176 0.000
J09-J18 Influenza and pneumonia
0.824 0.176 0.000
H92 Otalgia and effusion of ear
0.823 0.177 0.000
H10-H13 Disorders of conjunctiva
0.823 0.177 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.822 0.178 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.822 0.178 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.820 0.180 0.000
R47-R49 Symptoms and signs involving speech and voice
0.816 0.184 0.000
N73 Other female pelvic inflammatory diseases
0.810 0.190 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.809 0.191 0.000
J46 Status asthmaticus
0.809 0.191 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.809 0.191 0.000
G90 Disorders of autonomic nervous system
0.808 0.192 0.000
C64-C68 Malignant neoplasms of urinary tract
0.806 0.194 0.000
G93.8 Other specified disorders of brain
0.805 0.195 0.000
D64.9 Anaemia, unspecified
0.804 0.196 0.000
D68 Other coagulation defects
0.804 0.196 0.000
Chapter I Certain infectious and parasitic diseases
0.803 0.197 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.802 0.198 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.801 0.199 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.799 0.201 0.000
M45-M49 Spondylopathies
0.799 0.201 0.000
C50.0 Nipple and areola
0.799 0.201 0.000
J69 Pneumonitis due to solids and liquids
0.798 0.202 0.000
W00-W19 Falls
0.798 0.202 0.000
S20-S29 Injuries to the thorax
0.797 0.203 0.000
I27.2 Other secondary pulmonary hypertension
0.796 0.204 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.792 0.208 0.000
Y57 Other and unspecified drugs and medicaments
0.792 0.208 0.000
G93.9 Disorder of brain, unspecified
0.791 0.209 0.000
H44 Disorders of globe
0.791 0.209 0.000
I27.0 Primary pulmonary hypertension
0.788 0.212 0.000
J84 Other interstitial pulmonary diseases
0.787 0.213 0.000
Z51.0 Radiotherapy session
0.787 0.213 0.000
Z33 Pregnant state, incidental
0.786 0.214 0.000
C50.6 Axillary tail of breast
0.784 0.216 0.000
D86.9 Sarcoidosis, unspecified
0.784 0.216 0.000
W50-W64 Exposure to animate mechanical forces
0.780 0.220 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.780 0.220 0.000
I51.7 Cardiomegaly
0.777 0.223 0.000
N73.6 Female pelvic peritoneal adhesions
0.777 0.223 0.000
M80-M85 Disorders of bone density and structure
0.777 0.223 0.000
G43.1 Migraine with aura [classical migraine]
0.776 0.224 0.000
Z39.1 Care and examination of lactating mother
0.775 0.225 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.775 0.225 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.775 0.225 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.775 0.225 0.000
Z43.1 Attention to gastrostomy
0.774 0.226 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.774 0.226 0.000
J00 Acute nasopharyngitis [common cold]
0.773 0.227 0.000
Z35.5 Supervision of elderly primigravida
0.770 0.230 0.000
Q60-Q64 Congenital malformations of the urinary system
0.769 0.231 0.000
M62 Other disorders of muscle
0.769 0.231 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.769 0.231 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.767 0.232 0.000
H91.9 Hearing loss, unspecified
0.767 0.233 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.767 0.233 0.000
M70-M79 Other soft tissue disorders
0.766 0.234 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.765 0.235 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.765 0.235 0.000
I36 Nonrheumatic tricuspid valve disorders
0.765 0.235 0.000
X20-X29 Contact with venomous animals and plants
0.763 0.237 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.762 0.237 0.000
Y44 Agents primarily affecting blood constituents
0.762 0.238 0.000
H80-H83 Diseases of inner ear
0.762 0.238 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.762 0.238 0.000
I44 Atrioventricular and left bundle-branch block
0.762 0.238 0.000
C71 Malignant neoplasm of brain
0.759 0.241 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.758 0.242 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.757 0.243 0.000
V40-V49 Car occupant injured in transport accident
0.757 0.243 0.000
S00 Superficial injury of head
0.756 0.244 0.000
I60 Subarachnoid haemorrhage
0.755 0.245 0.000
R79 Other abnormal findings of blood chemistry
0.755 0.245 0.000
Z50.8 Care involving use of rehabilitation procedures
0.755 0.245 0.000
J42 Unspecified chronic bronchitis
0.755 0.245 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.753 0.247 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.753 0.247 0.000
S01 Open wound of head
0.752 0.247 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.752 0.248 0.000
H53-H54 Visual disturbances and blindness
0.752 0.248 0.000
Y00-Y09 Assault
0.752 0.248 0.000
N25-N29 Other disorders of kidney and ureter
0.751 0.249 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.751 0.249 0.000
C50.2 Upper-inner quadrant of breast
0.750 0.250 0.000
J90-J94 Other diseases of pleura
0.750 0.250 0.000
S32 Fracture of lumbar spine and pelvis
0.750 0.250 0.000
J02 Acute pharyngitis
0.750 0.250 0.000
D68.9 Coagulation defect, unspecified
0.749 0.251 0.000
Z45.1 Adjustment and management of infusion pump
0.749 0.251 0.000
S06 Intracranial injury
0.747 0.253 0.000
C79.2 Secondary malignant neoplasm of skin
0.747 0.253 0.000
H92.1 Otorrhoea
0.747 0.253 0.000
X50-X57 Overexertion, travel and privation
0.746 0.254 0.000
G70-G73 Diseases of myoneural junction and muscle
0.746 0.254 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.744 0.256 0.000
C85.1 B-cell lymphoma, unspecified
0.744 0.256 0.000
I08.8 Other multiple valve diseases
0.744 0.256 0.000
Z44 Fitting and adjustment of external prosthetic device
0.741 0.259 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.740 0.260 0.000
X60-X84 Intentional self-harm
0.740 0.260 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.739 0.261 0.000
L20-L30 Dermatitis and eczema
0.739 0.261 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.739 0.261 0.000
J69.0 Pneumonitis due to food and vomit
0.737 0.263 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.737 0.263 0.000
I67.2 Cerebral atherosclerosis
0.736 0.264 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.736 0.264 0.000
J43 Emphysema
0.736 0.264 0.000
D73.0 Hyposplenism
0.735 0.265 0.000
S90-S99 Injuries to the ankle and foot
0.733 0.267 0.000
D86.0 Sarcoidosis of lung
0.732 0.268 0.000
C50.9 Breast, unspecified
0.732 0.268 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.731 0.268 0.000
Y43.1 Antineoplastic antimetabolites
0.731 0.269 0.000
C77.9 Lymph node, unspecified
0.731 0.269 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.730 0.270 0.000
C50.1 Central portion of breast
0.729 0.271 0.000
S10-S19 Injuries to the neck
0.729 0.271 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.728 0.272 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.728 0.272 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.728 0.272 0.000
I49.8 Other specified cardiac arrhythmias
0.728 0.272 0.000
G93.6 Cerebral oedema
0.727 0.273 0.000
J18 Pneumonia, organism unspecified
0.726 0.274 0.000
Z40 Prophylactic surgery
0.726 0.274 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.725 0.275 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.723 0.277 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.723 0.277 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.723 0.277 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.722 0.278 0.000
Z50.0 Cardiac rehabilitation
0.721 0.279 0.000
D73.1 Hypersplenism
0.721 0.279 0.000
Z42 Follow-up care involving plastic surgery
0.721 0.279 0.000
M20-M25 Other joint disorders
0.720 0.280 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.720 0.280 0.000
M87 Osteonecrosis
0.719 0.281 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
H11 Other disorders of conjunctiva
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.715 0.284 0.000
C80 Malignant neoplasm without specification of site
0.715 0.285 0.000
Z39.0 Care and examination immediately after delivery
0.715 0.285 0.000
Z35.4 Supervision of pregnancy with grand multiparity
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.285 0.000
Z51.9 Medical care, unspecified
0.715 0.285 0.000
Z51.6 Desensitisation to allergens
0.715 0.285 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.714 0.286 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.714 0.286 0.000
L50-L54 Urticaria and erythema
0.713 0.287 0.000
N75 Diseases of Bartholin's gland
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.712 0.288 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.712 0.288 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.712 0.288 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.711 0.289 0.000
I62 Other nontraumatic intracranial haemorrhage
0.711 0.289 0.000
Z50.6 Orthoptic training
0.710 0.289 0.000
Z50.3 Drug rehabilitation
0.710 0.289 0.000
F80-F89 Disorders of psychological development
0.710 0.290 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.710 0.290 0.000
C95 Leukaemia of unspecified cell type
0.710 0.290 0.000
C94 Other leukaemias of specified cell type
0.710 0.290 0.000
C93 Monocytic leukaemia
0.710 0.290 0.000
C88 Malignant immunoproliferative diseases
0.710 0.290 0.000
C86 Other specified types of T/NK-cell lymphoma
0.710 0.290 0.000
I05 Rheumatic mitral valve diseases
0.710 0.290 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.709 0.291 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.709 0.291 0.000
G44 Other headache syndromes
0.708 0.292 0.000
C01 Malignant neoplasm of base of tongue
0.708 0.292 0.000
Z45.2 Adjustment and management of vascular access device
0.708 0.292 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.708 0.292 0.000
Y59 Other and unspecified vaccines and biological substances
0.707 0.293 0.000
Y58 Bacterial vaccines
0.707 0.293 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.707 0.293 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.707 0.293 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
Y48 Anaesthetics and therapeutic gases
0.707 0.293 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.707 0.293 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.707 0.293 0.000
I09 Other rheumatic heart diseases
0.707 0.293 0.000
I06 Rheumatic aortic valve diseases
0.707 0.293 0.000
G95 Other diseases of spinal cord
0.706 0.294 0.000
B35-B49 Mycoses
0.706 0.294 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.706 0.294 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.706 0.294 0.000
C85.0 Lymphosarcoma
0.706 0.294 0.000
M48 Other spondylopathies
0.705 0.295 0.000
H90 Conductive and sensorineural hearing loss
0.705 0.295 0.000
N72 Inflammatory disease of cervix uteri
0.704 0.296 0.000
R82 Other abnormal findings in urine
0.704 0.296 0.000
N70 Salpingitis and oophoritis
0.704 0.296 0.000
H93 Other disorders of ear, not elsewhere classified
0.704 0.296 0.000
G90.2 Horner's syndrome
0.704 0.296 0.000
G43.8 Other migraine
0.703 0.297 0.000
G20-G26 Extrapyramidal and movement disorders
0.702 0.298 0.000
C77.2 Intra-abdominal lymph nodes
0.702 0.298 0.000
M79.8 Other specified soft tissue disorders
0.702 0.298 0.000
C09 Malignant neoplasm of tonsil
0.701 0.299 0.000
H10 Conjunctivitis
0.699 0.301 0.000
Y43.9 Primarily systemic agent, unspecified
0.699 0.301 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.699 0.301 0.000
Y43.6 Enzymes, not elsewhere classified
0.699 0.301 0.000
Y43.5 Acidifying and alkalising agents
0.699 0.301 0.000
Y43.2 Antineoplastic natural products
0.699 0.301 0.000
F17.1 Harmful use
0.698 0.302 0.000
H61 Other disorders of external ear
0.698 0.302 0.000
C79.6 Secondary malignant neoplasm of ovary
0.697 0.303 0.000
G96 Other disorders of central nervous system
0.697 0.303 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.697 0.303 0.000
I51.4 Myocarditis, unspecified
0.696 0.303 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.696 0.304 0.000
D55-D59 Haemolytic anaemias
0.695 0.305 0.000
C73 Malignant neoplasm of thyroid gland
0.695 0.305 0.000
Z49 Care involving dialysis
0.694 0.305 0.000
Z38 Liveborn infants according to place of birth
0.694 0.305 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.694 0.306 0.000
J18.1 Lobar pneumonia, unspecified
0.693 0.307 0.000
C77.8 Lymph nodes of multiple regions
0.693 0.307 0.000
G47 Sleep disorders
0.693 0.307 0.000
H55-H59 Other disorders of eye and adnexa
0.693 0.307 0.000
V20-V29 Motorcycle rider injured in transport accident
0.692 0.308 0.000
Z51.8 Other specified medical care
0.692 0.308 0.000
M62.8 Other specified disorders of muscle
0.692 0.308 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.692 0.308 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.691 0.308 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.691 0.309 0.000
Q28 Other congenital malformations of circulatory system
0.691 0.309 0.000
I45.1 Other and unspecified right bundle-branch block
0.690 0.310 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.689 0.311 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.689 0.311 0.000
I67.5 Moyamoya disease
0.689 0.311 0.000
I67.4 Hypertensive encephalopathy
0.689 0.311 0.000
I67.3 Progressive vascular leukoencephalopathy
0.689 0.311 0.000
G41 Status epilepticus
0.689 0.311 0.000
H83 Other diseases of inner ear
0.689 0.311 0.000
H44.0 Purulent endophthalmitis
0.688 0.312 0.000
I47.2 Ventricular tachycardia
0.688 0.312 0.000
C50.4 Upper-outer quadrant of breast
0.687 0.313 0.000
H91.8 Other specified hearing loss
0.687 0.313 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.686 0.314 0.000
D74 Methaemoglobinaemia
0.686 0.314 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.686 0.314 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.686 0.314 0.000
I51.0 Cardiac septal defect, acquired
0.685 0.315 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.684 0.316 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.684 0.316 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
G92 Toxic encephalopathy
0.684 0.316 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.683 0.317 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.682 0.318 0.000
I33 Acute and subacute endocarditis
0.681 0.319 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.681 0.319 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.681 0.319 0.000
R81 Glycosuria
0.680 0.320 0.000
I42.8 Other cardiomyopathies
0.680 0.320 0.000
Z39.2 Routine postpartum follow-up
0.679 0.321 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.679 0.321 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.679 0.321 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.679 0.321 0.000
Y43.4 Immunosuppressive agents
0.679 0.321 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.678 0.322 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.678 0.322 0.000
M90 Osteopathies in diseases classified elsewhere
0.677 0.323 0.000
I45.5 Other specified heart block
0.677 0.323 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.675 0.325 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.675 0.325 0.000
I07.9 Tricuspid valve disease, unspecified
0.674 0.326 0.000
I07.8 Other tricuspid valve diseases
0.674 0.326 0.000
I07.2 Tricuspid stenosis with insufficiency
0.674 0.326 0.000
I07.0 Tricuspid stenosis
0.674 0.326 0.000
M91-M94 Chondropathies
0.674 0.326 0.000
S02 Fracture of skull and facial bones
0.674 0.326 0.000
V80-V89 Other land transport accidents
0.674 0.326 0.000
D62 Acute posthaemorrhagic anaemia
0.673 0.327 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.673 0.327 0.000
H44.2 Degenerative myopia
0.672 0.328 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.672 0.328 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.672 0.328 0.000
M85 Other disorders of bone density and structure
0.672 0.328 0.000
S31 Open wound of abdomen, lower back and pelvis
0.672 0.328 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.672 0.328 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.672 0.328 0.000
C34 Malignant neoplasm of bronchus and lung
0.672 0.328 0.000
I51.9 Heart disease, unspecified
0.671 0.329 0.000
I47.1 Supraventricular tachycardia
0.671 0.329 0.000
D86.1 Sarcoidosis of lymph nodes
0.671 0.329 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.671 0.329 0.000
Z32 Pregnancy examination and test
0.670 0.330 0.000
Chapter XXII Codes for special purposes
0.669 0.331 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.669 0.331 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.669 0.331 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.668 0.332 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.667 0.333 0.000
I49.2 Junctional premature depolarisation
0.667 0.333 0.000
S05 Injury of eye and orbit
0.667 0.333 0.000
R47 Speech disturbances, not elsewhere classified
0.667 0.333 0.000
W19 Unspecified fall
0.667 0.333 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.666 0.334 0.000
I42.6 Alcoholic cardiomyopathy
0.666 0.334 0.000
I42.5 Other restrictive cardiomyopathy
0.666 0.334 0.000
I42.4 Endocardial fibroelastosis
0.666 0.334 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.666 0.334 0.000
G93.7 Reye's syndrome
0.666 0.334 0.000
G93.5 Compression of brain
0.666 0.334 0.000
G93.4 Encephalopathy, unspecified
0.666 0.334 0.000
G93.2 Benign intracranial hypertension
0.666 0.334 0.000
C51-C58 Malignant neoplasms of female genital organs
0.666 0.334 0.000
M89 Other disorders of bone
0.666 0.334 0.000
Y52 Agents primarily affecting the cardiovascular system
0.666 0.334 0.000
I61 Intracerebral haemorrhage
0.665 0.335 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.664 0.335 0.000
N60-N64 Disorders of breast
0.664 0.336 0.000
T33-T35 Frostbite
0.663 0.337 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.663 0.337 0.000
T00-T07 Injuries involving multiple body regions
0.663 0.337 0.000
R49 Voice disturbances
0.663 0.337 0.000
R30-R39 Symptoms and signs involving the urinary system
0.663 0.337 0.000
D66 Hereditary factor VIII deficiency
0.662 0.338 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.662 0.338 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.662 0.338 0.000
Q35-Q37 Cleft lip and cleft palate
0.662 0.338 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.662 0.338 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.662 0.338 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.662 0.338 0.000
J06.9 Acute upper respiratory infection, unspecified
0.662 0.338 0.000
I51.6 Cardiovascular disease, unspecified
0.661 0.338 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.661 0.339 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.661 0.339 0.000
I08.9 Multiple valve disease, unspecified
0.661 0.339 0.000
S01.0 Open wound of scalp
0.661 0.339 0.000
H65-H75 Diseases of middle ear and mastoid
0.661 0.339 0.000
R76 Other abnormal immunological findings in serum
0.660 0.340 0.000
Y40 Systemic antibiotics
0.660 0.340 0.000
C50.5 Lower-outer quadrant of breast
0.660 0.340 0.000
S32.5 Fracture of pubis
0.660 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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