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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117270429
log Bayes Factor = 18.3316
Chromosome 21   position 38,124,803  (GRCh37) Explore rs117270429 on Ensembl!
Variant rs117270429 is part of Cluster X0087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.998 0.002 0.000
Z51 Other medical care
0.997 0.003 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.994 0.006 0.000
Chapter X Diseases of the respiratory system
0.992 0.008 0.000
M05-M14 Inflammatory polyarthropathies
0.992 0.008 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.991 0.009 0.000
S60-S69 Injuries to the wrist and hand
0.984 0.016 0.000
Chapter XIV Diseases of the genitourinary system
0.983 0.017 0.000
M06 Other rheumatoid arthritis
0.982 0.018 0.000
Z42 Follow-up care involving plastic surgery
0.978 0.022 0.000
Z51.1 Chemotherapy session for neoplasm
0.977 0.023 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.977 0.023 0.000
M06.9 Rheumatoid arthritis, unspecified
0.975 0.025 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.971 0.029 0.000
M20-M25 Other joint disorders
0.968 0.032 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.968 0.032 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.967 0.033 0.000
N10-N16 Renal tubulo-interstitial diseases
0.963 0.037 0.000
D00-D09 In situ neoplasms
0.962 0.038 0.000
Chapter VI Diseases of the nervous system
0.960 0.040 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.956 0.044 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.956 0.044 0.000
Chapter V Mental and behavioural disorders
0.954 0.046 0.000
R21 Rash and other nonspecific skin eruption
0.947 0.053 0.000
C34 Malignant neoplasm of bronchus and lung
0.946 0.054 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.942 0.058 0.000
M25 Other joint disorders, not elsewhere classified
0.940 0.060 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.931 0.069 0.000
Chapter XX External causes of morbidity and mortality
0.930 0.070 0.000
L60-L75 Disorders of skin appendages
0.929 0.071 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.929 0.071 0.000
J90-J94 Other diseases of pleura
0.929 0.071 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.927 0.073 0.000
Chapter XI Diseases of the digestive system
0.924 0.076 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.923 0.077 0.000
L20-L30 Dermatitis and eczema
0.917 0.083 0.000
N13 Obstructive and reflux uropathy
0.916 0.084 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.913 0.087 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.913 0.087 0.000
M80-M85 Disorders of bone density and structure
0.910 0.090 0.000
J00-J06 Acute upper respiratory infections
0.907 0.093 0.000
S90-S99 Injuries to the ankle and foot
0.905 0.095 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.904 0.096 0.000
K90-K93 Other diseases of the digestive system
0.904 0.096 0.000
Chapter VIII Diseases of the ear and mastoid process
0.903 0.097 0.000
D05 Carcinoma in situ of breast
0.897 0.103 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.897 0.103 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.896 0.104 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.892 0.108 0.000
N60-N64 Disorders of breast
0.892 0.108 0.000
S40-S49 Injuries to the shoulder and upper arm
0.890 0.110 0.000
K92 Other diseases of digestive system
0.889 0.111 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.889 0.111 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.888 0.112 0.000
C64-C68 Malignant neoplasms of urinary tract
0.882 0.118 0.000
J90 Pleural effusion, not elsewhere classified
0.881 0.119 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.879 0.121 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.877 0.123 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.873 0.127 0.000
R50-R69 General symptoms and signs
0.873 0.127 0.000
K92.1 Melaena
0.872 0.128 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.872 0.128 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.871 0.129 0.000
Z51.5 Palliative care
0.868 0.132 0.000
C34.1 Upper lobe, bronchus or lung
0.861 0.139 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.858 0.142 0.000
C77.0 Lymph nodes of head, face and neck
0.858 0.142 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.858 0.142 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.856 0.144 0.000
L50-L54 Urticaria and erythema
0.855 0.145 0.000
C34.9 Bronchus or lung, unspecified
0.854 0.146 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.853 0.147 0.000
M25.5 Pain in joint
0.853 0.147 0.000
S64 Injury of nerves at wrist and hand level
0.852 0.148 0.000
R50 Fever of unknown origin
0.850 0.150 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.844 0.156 0.000
D05.1 Intraductal carcinoma in situ
0.840 0.160 0.000
C78.0 Secondary malignant neoplasm of lung
0.840 0.160 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.840 0.160 0.000
G90-G99 Other disorders of the nervous system
0.839 0.161 0.000
S62 Fracture at wrist and hand level
0.838 0.162 0.000
S61 Open wound of wrist and hand
0.836 0.164 0.000
Z41 Procedures for purposes other than remedying health state
0.836 0.164 0.000
C77.1 Intrathoracic lymph nodes
0.835 0.165 0.000
C77.2 Intra-abdominal lymph nodes
0.834 0.166 0.000
N76 Other inflammation of vagina and vulva
0.834 0.166 0.000
C79 Secondary malignant neoplasm of other sites
0.834 0.166 0.000
Z40 Prophylactic surgery
0.832 0.168 0.000
M07 Psoriatic and enteropathic arthropathies
0.832 0.168 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.832 0.168 0.000
M23 Internal derangement of knee
0.831 0.169 0.000
L40-L45 Papulosquamous disorders
0.830 0.170 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.830 0.170 0.000
C78.2 Secondary malignant neoplasm of pleura
0.829 0.171 0.000
L29 Pruritus
0.829 0.171 0.000
O60-O75 Complications of labour and delivery
0.828 0.172 0.000
R50.9 Fever, unspecified
0.828 0.172 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.827 0.173 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.824 0.176 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.822 0.178 0.000
S00-S09 Injuries to the head
0.822 0.178 0.000
J03 Acute tonsillitis
0.820 0.180 0.000
Z51.2 Other chemotherapy
0.819 0.181 0.000
T39.1 4-Aminophenol derivatives
0.818 0.182 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.818 0.182 0.000
G35 Multiple sclerosis
0.816 0.184 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.815 0.185 0.000
N63 Unspecified lump in breast
0.810 0.190 0.000
J09-J18 Influenza and pneumonia
0.810 0.190 0.000
T51 Toxic effect of alcohol
0.809 0.191 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.806 0.194 0.000
C77.8 Lymph nodes of multiple regions
0.806 0.194 0.000
L27 Dermatitis due to substances taken internally
0.805 0.195 0.000
M84 Disorders of continuity of bone
0.804 0.196 0.000
M10 Gout
0.803 0.197 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.803 0.197 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.802 0.198 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.802 0.198 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.800 0.200 0.000
Z52 Donors of organs and tissues
0.799 0.201 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.798 0.202 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.798 0.202 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.797 0.203 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.796 0.204 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.795 0.205 0.000
L72.1 Trichilemmal cyst
0.795 0.205 0.000
Chapter VII Diseases of the eye and adnexa
0.795 0.205 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.794 0.206 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.794 0.206 0.000
K12 Stomatitis and related lesions
0.793 0.207 0.000
N72 Inflammatory disease of cervix uteri
0.789 0.211 0.000
J95-J99 Other diseases of the respiratory system
0.788 0.212 0.000
N13.3 Other and unspecified hydronephrosis
0.787 0.213 0.000
R52 Pain, not elsewhere classified
0.787 0.213 0.000
M91-M94 Chondropathies
0.786 0.214 0.000
G20-G26 Extrapyramidal and movement disorders
0.786 0.214 0.000
M81 Osteoporosis without pathological fracture
0.785 0.215 0.000
S20-S29 Injuries to the thorax
0.784 0.216 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.782 0.218 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.781 0.219 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.780 0.220 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.779 0.221 0.000
C80 Malignant neoplasm without specification of site
0.778 0.222 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.778 0.222 0.000
Z54 Convalescence
0.775 0.225 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.775 0.225 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.773 0.227 0.000
M25.7 Osteophyte
0.772 0.227 0.000
R23 Other skin changes
0.772 0.228 0.000
K70-K77 Diseases of liver
0.770 0.230 0.000
R94 Abnormal results of function studies
0.770 0.230 0.000
R47-R49 Symptoms and signs involving speech and voice
0.769 0.231 0.000
H65-H75 Diseases of middle ear and mastoid
0.769 0.231 0.000
L72.0 Epidermal cyst
0.769 0.231 0.000
Z51.9 Medical care, unspecified
0.769 0.231 0.000
C34.3 Lower lobe, bronchus or lung
0.768 0.232 0.000
Z51.3 Blood transfusion without reported diagnosis
0.766 0.234 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.765 0.235 0.000
S90 Superficial injury of ankle and foot
0.765 0.235 0.000
C67 Malignant neoplasm of bladder
0.764 0.236 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.764 0.236 0.000
N70 Salpingitis and oophoritis
0.763 0.237 0.000
N85.0 Endometrial glandular hyperplasia
0.762 0.238 0.000
M22 Disorders of patella
0.761 0.239 0.000
F80-F89 Disorders of psychological development
0.760 0.240 0.000
M24 Other specific joint derangements
0.760 0.240 0.000
M25.3 Other instability of joint
0.760 0.240 0.000
W20-W49 Exposure to inanimate mechanical forces
0.758 0.242 0.000
S64.4 Injury of digital nerve of other finger
0.757 0.243 0.000
J03.9 Acute tonsillitis, unspecified
0.757 0.243 0.000
N87 Dysplasia of cervix uteri
0.757 0.243 0.000
S10-S19 Injuries to the neck
0.757 0.243 0.000
S92 Fracture of foot, except ankle
0.756 0.244 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.756 0.244 0.000
Z85 Personal history of malignant neoplasm
0.756 0.244 0.000
H30-H36 Disorders of choroid and retina
0.755 0.245 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.754 0.246 0.000
H60-H62 Diseases of external ear
0.754 0.246 0.000
J20-J22 Other acute lower respiratory infections
0.753 0.247 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.752 0.248 0.000
F10.2 Dependence syndrome
0.751 0.249 0.000
O85-O92 Complications predominantly related to the puerperium
0.751 0.249 0.000
M31 Other necrotising vasculopathies
0.750 0.250 0.000
C51-C58 Malignant neoplasms of female genital organs
0.750 0.250 0.000
T51.0 Ethanol
0.749 0.251 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.749 0.251 0.000
Z46 Fitting and adjustment of other devices
0.749 0.251 0.000
K92.9 Disease of digestive system, unspecified
0.749 0.251 0.000
N11 Chronic tubulo-interstitial nephritis
0.745 0.254 0.000
M06.0 Seronegative rheumatoid arthritis
0.745 0.255 0.000
X50-X57 Overexertion, travel and privation
0.745 0.255 0.000
Z51.0 Radiotherapy session
0.744 0.256 0.000
G93 Other disorders of brain
0.744 0.256 0.000
L53 Other erythematous conditions
0.744 0.256 0.000
J02 Acute pharyngitis
0.744 0.256 0.000
V10-V19 Pedal cyclist injured in transport accident
0.743 0.257 0.000
J92 Pleural plaque
0.742 0.257 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.742 0.258 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.741 0.259 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.740 0.260 0.000
M86-M90 Other osteopathies
0.739 0.261 0.000
L29.9 Pruritus, unspecified
0.738 0.262 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.738 0.262 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.737 0.263 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.737 0.263 0.000
N25-N29 Other disorders of kidney and ureter
0.736 0.264 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.736 0.264 0.000
K65-K67 Diseases of peritoneum
0.736 0.264 0.000
K11 Diseases of salivary glands
0.735 0.265 0.000
N85.1 Endometrial adenomatous hyperplasia
0.735 0.265 0.000
T91 Sequelae of injuries of neck and trunk
0.733 0.267 0.000
R68 Other general symptoms and signs
0.733 0.267 0.000
N83.0 Follicular cyst of ovary
0.733 0.267 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.732 0.268 0.000
D06 Carcinoma in situ of cervix uteri
0.732 0.268 0.000
O00-O08 Pregnancy with abortive outcome
0.731 0.269 0.000
J86 Pyothorax
0.731 0.269 0.000
F99-F99 Unspecified mental disorder
0.730 0.270 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.730 0.270 0.000
H35 Other retinal disorders
0.730 0.270 0.000
C50-C50 Malignant neoplasm of breast
0.730 0.270 0.000
D04 Carcinoma in situ of skin
0.729 0.271 0.000
V80-V89 Other land transport accidents
0.729 0.271 0.000
N99-N99 Other disorders of the genitourinary system
0.729 0.271 0.000
Z71.8 Other specified counselling
0.729 0.271 0.000
F60-F69 Disorders of adult personality and behaviour
0.729 0.271 0.000
S42 Fracture of shoulder and upper arm
0.728 0.272 0.000
Y86 Sequelae of other accidents
0.728 0.272 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.728 0.272 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.726 0.274 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.725 0.275 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.725 0.275 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.725 0.275 0.000
N88 Other noninflammatory disorders of cervix uteri
0.724 0.276 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.724 0.276 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.723 0.276 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.723 0.277 0.000
H90-H95 Other disorders of ear
0.723 0.277 0.000
C34.0 Main bronchus
0.723 0.277 0.000
C77.9 Lymph node, unspecified
0.722 0.278 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.720 0.280 0.000
N76.4 Abscess of vulva
0.720 0.280 0.000
M25.4 Effusion of joint
0.720 0.280 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.720 0.280 0.000
M21 Other acquired deformities of limbs
0.719 0.280 0.000
O70 Perineal laceration during delivery
0.719 0.281 0.000
M07.3 Other psoriatic arthropathies
0.718 0.282 0.000
S00 Superficial injury of head
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C77.3 Axillary and upper limb lymph nodes
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M25.76 Osteophyte (Lower leg)
0.717 0.283 0.000
N13.6 Pyonephrosis
0.716 0.284 0.000
K12.1 Other forms of stomatitis
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.284 0.000
Z49 Care involving dialysis
0.715 0.285 0.000
Z44 Fitting and adjustment of external prosthetic device
0.715 0.285 0.000
Z80 Family history of malignant neoplasm
0.715 0.285 0.000
Z51.6 Desensitisation to allergens
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
S67 Crushing injury of wrist and hand
0.714 0.286 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.714 0.286 0.000
T92 Sequelae of injuries of upper limb
0.714 0.286 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.713 0.287 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.713 0.287 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.712 0.288 0.000
T93 Sequelae of injuries of lower limb
0.711 0.289 0.000
M14 Arthropathies in other diseases classified elsewhere
0.711 0.289 0.000
M12 Other specific arthropathies
0.711 0.289 0.000
M11 Other crystal arthropathies
0.711 0.289 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.711 0.289 0.000
M08 Juvenile arthritis
0.711 0.289 0.000
R61 Hyperhidrosis
0.711 0.289 0.000
L10-L14 Bullous disorders
0.711 0.289 0.000
N13.4 Hydroureter
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.710 0.290 0.000
G81 Hemiplegia
0.709 0.291 0.000
J04 Acute laryngitis and tracheitis
0.709 0.291 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.709 0.291 0.000
M25.56 Pain in joint (Lower leg)
0.709 0.291 0.000
D09 Carcinoma in situ of other and unspecified sites
0.709 0.291 0.000
T90 Sequelae of injuries of head
0.708 0.292 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.708 0.292 0.000
M23.8 Other internal derangements of knee
0.707 0.293 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.707 0.293 0.000
Z51.8 Other specified medical care
0.707 0.293 0.000
L40 Psoriasis
0.707 0.293 0.000
T66-T78 Other and unspecified effects of external causes
0.707 0.293 0.000
R52.1 Chronic intractable pain
0.707 0.293 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.706 0.293 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.706 0.294 0.000
S69 Other and unspecified injuries of wrist and hand
0.705 0.295 0.000
S65 Injury of blood vessels at wrist and hand level
0.705 0.295 0.000
M06.8 Other specified rheumatoid arthritis
0.704 0.296 0.000
M06.4 Inflammatory polyarthropathy
0.704 0.296 0.000
M06.3 Rheumatoid nodule
0.704 0.296 0.000
M06.2 Rheumatoid bursitis
0.704 0.296 0.000
M06.1 Adult-onset Still's disease
0.704 0.296 0.000
S50-S59 Injuries to the elbow and forearm
0.703 0.297 0.000
M65-M68 Disorders of synovium and tendon
0.703 0.297 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.702 0.298 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.701 0.299 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.701 0.299 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.701 0.299 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.701 0.299 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.701 0.299 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.701 0.299 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.701 0.299 0.000
L85 Other epidermal thickening
0.700 0.299 0.000
S32 Fracture of lumbar spine and pelvis
0.700 0.300 0.000
C78.7 Secondary malignant neoplasm of liver
0.700 0.300 0.000
N13.8 Other obstructive and reflux uropathy
0.700 0.300 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.699 0.301 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.699 0.301 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.699 0.301 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.699 0.301 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.699 0.301 0.000
M25.57 Pain in joint (Ankle and foot)
0.698 0.302 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.698 0.302 0.000
M25.53 Pain in joint (Forearm)
0.698 0.302 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.697 0.302 0.000
S41 Open wound of shoulder and upper arm
0.697 0.303 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.697 0.303 0.000
N61 Inflammatory disorders of breast
0.696 0.303 0.000
C77.4 Inguinal and lower limb lymph nodes
0.696 0.304 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.696 0.304 0.000
N83.2 Other and unspecified ovarian cysts
0.696 0.304 0.000
M81.9 Osteoporosis, unspecified
0.696 0.304 0.000
R22.1 Localised swelling, mass and lump, neck
0.695 0.305 0.000
L71 Rosacea
0.695 0.305 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.694 0.306 0.000
M34 Systemic sclerosis
0.694 0.306 0.000
M33 Dermatopolymyositis
0.694 0.306 0.000
M32 Systemic lupus erythematosus
0.694 0.306 0.000
M30 Polyarteritis nodosa and related conditions
0.694 0.306 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.694 0.306 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.694 0.306 0.000
C32 Malignant neoplasm of larynx
0.694 0.306 0.000
C31 Malignant neoplasm of accessory sinuses
0.694 0.306 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.694 0.306 0.000
C37 Malignant neoplasm of thymus
0.694 0.306 0.000
C33 Malignant neoplasm of trachea
0.694 0.306 0.000
M25.8 Other specified joint disorders
0.694 0.306 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.694 0.306 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.693 0.307 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.693 0.307 0.000
F10.0 Acute intoxication
0.693 0.307 0.000
K13 Other diseases of lip and oral mucosa
0.692 0.307 0.000
O70.1 Second degree perineal laceration during delivery
0.692 0.308 0.000
S70-S79 Injuries to the hip and thigh
0.691 0.308 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.691 0.308 0.000
Z45 Adjustment and management of implanted device
0.691 0.309 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.691 0.309 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.690 0.309 0.000
N15 Other renal tubulo-interstitial diseases
0.690 0.309 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.690 0.309 0.000
N10 Acute tubulo-interstitial nephritis
0.690 0.309 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.690 0.309 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.690 0.310 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.690 0.310 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.690 0.310 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.690 0.310 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.690 0.310 0.000
E10-E14 Diabetes mellitus
0.690 0.310 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.689 0.310 0.000
N76.8 Other specified inflammation of vagina and vulva
0.689 0.311 0.000
G70-G73 Diseases of myoneural junction and muscle
0.688 0.312 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.688 0.312 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.687 0.313 0.000
Z73 Problems related to life-management difficulty
0.686 0.314 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.686 0.314 0.000
J30-J39 Other diseases of upper respiratory tract
0.686 0.314 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.686 0.314 0.000
M13 Other arthritis
0.686 0.314 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.685 0.315 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.685 0.315 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.685 0.315 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.685 0.315 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.685 0.315 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.685 0.315 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.685 0.315 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.685 0.315 0.000
T36 Poisoning by systemic antibiotics
0.685 0.315 0.000
K90 Intestinal malabsorption
0.685 0.315 0.000
S62.2 Fracture of first metacarpal bone
0.685 0.315 0.000
Z80.3 Family history of malignant neoplasm of breast
0.685 0.315 0.000
S60 Superficial injury of wrist and hand
0.684 0.316 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.684 0.316 0.000
F70-F79 Mental retardation
0.684 0.316 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.684 0.316 0.000
N64 Other disorders of breast
0.683 0.316 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.683 0.317 0.000
L73 Other follicular disorders
0.683 0.317 0.000
C79.6 Secondary malignant neoplasm of ovary
0.682 0.318 0.000
D03 Melanoma in situ
0.682 0.318 0.000
T79-T79 Certain early complications of trauma
0.681 0.319 0.000
N85.2 Hypertrophy of uterus
0.680 0.320 0.000
Chapter XXII Codes for special purposes
0.679 0.320 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.679 0.321 0.000
C34.8 Overlapping lesion of bronchus and lung
0.678 0.322 0.000
C34.2 Middle lobe, bronchus or lung
0.678 0.322 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.678 0.322 0.000
Z91.6 Personal history of other physical trauma
0.676 0.324 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.676 0.324 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.676 0.324 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.676 0.324 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.676 0.324 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.675 0.324 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.675 0.325 0.000
R50.0 Fever with chills
0.675 0.325 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.675 0.325 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.674 0.326 0.000
Z94 Transplanted organ and tissue status
0.674 0.326 0.000
M25.9 Joint disorder, unspecified
0.674 0.326 0.000
M25.2 Flail joint
0.674 0.326 0.000
M25.1 Fistula of joint
0.674 0.326 0.000
M25.0 Haemarthrosis
0.674 0.326 0.000
N60 Benign mammary dysplasia
0.673 0.327 0.000
N87.1 Moderate cervical dysplasia
0.672 0.328 0.000
G91 Hydrocephalus
0.671 0.329 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.670 0.330 0.000
N83.1 Corpus luteum cyst
0.669 0.331 0.000
M10.9 Gout, unspecified
0.668 0.332 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.668 0.332 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.668 0.332 0.000
M05 Seropositive rheumatoid arthritis
0.668 0.332 0.000
S61.8 Open wound of other parts of wrist and hand
0.667 0.333 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.667 0.333 0.000
Y35-Y36 Legal intervention and operations of war
0.667 0.333 0.000
Y10-Y34 Event of undetermined intent
0.667 0.333 0.000
Y00-Y09 Assault
0.667 0.333 0.000
X85-X99 Assault
0.667 0.333 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.667 0.333 0.000
X30-X39 Exposure to forces of nature
0.667 0.333 0.000
X20-X29 Contact with venomous animals and plants
0.667 0.333 0.000
X10-X19 Contact with heat and hot substances
0.667 0.333 0.000
X00-X09 Exposure to smoke, fire and flames
0.667 0.333 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.667 0.333 0.000
W75-W84 Other accidental threats to breathing
0.667 0.333 0.000
W65-W74 Accidental drowning and submersion
0.667 0.333 0.000
W50-W64 Exposure to animate mechanical forces
0.667 0.333 0.000
V98-V99 Other and unspecified transport accidents
0.667 0.333 0.000
V95-V97 Air and space transport accidents
0.667 0.333 0.000
V90-V94 Water transport accidents
0.667 0.333 0.000
V70-V79 Bus occupant injured in transport accident
0.667 0.333 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.667 0.333 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.667 0.333 0.000
V40-V49 Car occupant injured in transport accident
0.667 0.333 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.667 0.333 0.000
V01-V09 Pedestrian injured in transport accident
0.667 0.333 0.000
H60 Otitis externa
0.667 0.333 0.000
L75 Apocrine sweat disorders
0.666 0.334 0.000
L74 Eccrine sweat disorders
0.666 0.334 0.000
L70 Acne
0.666 0.334 0.000
L68 Hypertrichosis
0.666 0.334 0.000
L67 Hair colour and hair shaft abnormalities
0.666 0.334 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.666 0.334 0.000
L65 Other nonscarring hair loss
0.666 0.334 0.000
L64 Androgenic alopecia
0.666 0.334 0.000
L63 Alopecia areata
0.666 0.334 0.000
L62 Nail disorders in diseases classified elsewhere
0.666 0.334 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.666 0.334 0.000
J94 Other pleural conditions
0.666 0.334 0.000
K01 Embedded and impacted teeth
0.666 0.334 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.666 0.334 0.000
F30-F39 Mood [affective] disorders
0.665 0.335 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.665 0.335 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.664 0.336 0.000
N71 Inflammatory disease of uterus, except cervix
0.664 0.336 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.664 0.336 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.664 0.336 0.000
L53.9 Erythematous condition, unspecified
0.664 0.336 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.663 0.337 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.663 0.337 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.663 0.337 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.663 0.337 0.000
T87 Complications peculiar to reattachment and amputation
0.662 0.338 0.000
T86 Failure and rejection of transplanted organs and tissues
0.662 0.338 0.000
K05 Gingivitis and periodontal diseases
0.661 0.339 0.000
O42 Premature rupture of membranes
0.661 0.339 0.000
G30-G32 Other degenerative diseases of the nervous system
0.661 0.339 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.661 0.339 0.000
J84 Other interstitial pulmonary diseases
0.661 0.339 0.000
C09 Malignant neoplasm of tonsil
0.660 0.340 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.660 0.340 0.000
E20-E35 Disorders of other endocrine glands
0.660 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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