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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117531393
log Bayes Factor = 17.074
Chromosome 18   position 25,835,185  (GRCh37) Explore rs117531393 on Ensembl!
Variant rs117531393 is part of Cluster X0087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Z86 Personal history of certain other diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
C50-C50 Malignant neoplasm of breast
0.992 0.008 0.000
J09-J18 Influenza and pneumonia
0.990 0.010 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.990 0.010 0.000
Chapter V Mental and behavioural disorders
0.987 0.013 0.000
C50 Malignant neoplasm of breast
0.986 0.014 0.000
T81 Complications of procedures, not elsewhere classified
0.984 0.016 0.000
J18 Pneumonia, organism unspecified
0.983 0.017 0.000
J95-J99 Other diseases of the respiratory system
0.982 0.018 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
Z86.4 Personal history of psychoactive substance abuse
0.979 0.021 0.000
C50.9 Breast, unspecified
0.979 0.021 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.978 0.022 0.000
J18.1 Lobar pneumonia, unspecified
0.976 0.024 0.000
Z86.7 Personal history of diseases of the circulatory system
0.970 0.030 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.970 0.030 0.000
F41 Other anxiety disorders
0.970 0.030 0.000
J98 Other respiratory disorders
0.970 0.030 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.969 0.031 0.000
F41.9 Anxiety disorder, unspecified
0.962 0.038 0.000
Z90.1 Acquired absence of breast(s)
0.962 0.038 0.000
M20-M25 Other joint disorders
0.958 0.042 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.958 0.042 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.958 0.042 0.000
M70-M79 Other soft tissue disorders
0.952 0.048 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.949 0.051 0.000
M50-M54 Other dorsopathies
0.947 0.053 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.946 0.054 0.000
M20 Acquired deformities of fingers and toes
0.945 0.055 0.000
C78.7 Secondary malignant neoplasm of liver
0.942 0.058 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.942 0.058 0.000
Chapter IX Diseases of the circulatory system
0.927 0.073 0.000
Chapter VIII Diseases of the ear and mastoid process
0.925 0.075 0.000
C77.3 Axillary and upper limb lymph nodes
0.923 0.077 0.000
J98.1 Pulmonary collapse
0.922 0.078 0.000
M20.5 Other deformities of toe(s) (acquired)
0.921 0.079 0.000
J98.4 Other disorders of lung
0.916 0.084 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.914 0.086 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.909 0.091 0.000
Z98 Other postsurgical states
0.900 0.100 0.000
C15-C26 Malignant neoplasms of digestive organs
0.897 0.103 0.000
Chapter VI Diseases of the nervous system
0.895 0.105 0.000
I30-I52 Other forms of heart disease
0.888 0.112 0.000
Z94 Transplanted organ and tissue status
0.881 0.119 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.870 0.130 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.870 0.130 0.000
M20.1 Hallux valgus (acquired)
0.867 0.133 0.000
M54 Dorsalgia
0.867 0.133 0.000
Chapter XIV Diseases of the genitourinary system
0.866 0.134 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.865 0.135 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.865 0.135 0.000
Z92 Personal history of medical treatment
0.863 0.137 0.000
J30-J39 Other diseases of upper respiratory tract
0.863 0.137 0.000
M79.6 Pain in limb
0.862 0.138 0.000
M79.8 Other specified soft tissue disorders
0.861 0.139 0.000
Z98.0 Intestinal bypass and anastomosis status
0.855 0.145 0.000
C79 Secondary malignant neoplasm of other sites
0.849 0.150 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.849 0.151 0.000
I34 Nonrheumatic mitral valve disorders
0.848 0.152 0.000
M79.1 Myalgia
0.847 0.153 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.846 0.154 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.842 0.158 0.000
N17-N19 Renal failure
0.841 0.159 0.000
M05-M14 Inflammatory polyarthropathies
0.838 0.162 0.000
C78.2 Secondary malignant neoplasm of pleura
0.836 0.164 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.834 0.166 0.000
M86-M90 Other osteopathies
0.833 0.167 0.000
M50 Cervical disk disorders
0.831 0.169 0.000
F60-F69 Disorders of adult personality and behaviour
0.830 0.170 0.000
C50.1 Central portion of breast
0.828 0.172 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.828 0.172 0.000
M54.5 Low back pain
0.824 0.176 0.000
M35 Other systemic involvement of connective tissue
0.824 0.176 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.820 0.180 0.000
Y43 Primarily systemic agents
0.820 0.180 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.817 0.183 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.815 0.185 0.000
T86 Failure and rejection of transplanted organs and tissues
0.814 0.186 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.813 0.187 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.811 0.189 0.000
M15-M19 Arthrosis
0.810 0.190 0.000
Z88.0 Personal history of allergy to penicillin
0.810 0.190 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.809 0.191 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.808 0.192 0.000
Z91.5 Personal history of self-harm
0.807 0.193 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.807 0.193 0.000
N17 Acute renal failure
0.806 0.194 0.000
J90-J94 Other diseases of pleura
0.804 0.195 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.801 0.199 0.000
J20-J22 Other acute lower respiratory infections
0.800 0.200 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.800 0.200 0.000
I05-I09 Chronic rheumatic heart diseases
0.796 0.204 0.000
Chapter XXII Codes for special purposes
0.794 0.205 0.000
G40-G47 Episodic and paroxysmal disorders
0.792 0.208 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.792 0.208 0.000
Z93 Artificial opening status
0.789 0.210 0.000
M80-M85 Disorders of bone density and structure
0.789 0.211 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.788 0.212 0.000
I34.0 Mitral (valve) insufficiency
0.786 0.214 0.000
H80-H83 Diseases of inner ear
0.786 0.214 0.000
H90-H95 Other disorders of ear
0.786 0.214 0.000
F99-F99 Unspecified mental disorder
0.785 0.215 0.000
J18.9 Pneumonia, unspecified
0.783 0.217 0.000
T66-T78 Other and unspecified effects of external causes
0.782 0.218 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.782 0.218 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.781 0.219 0.000
N17.9 Acute renal failure, unspecified
0.781 0.219 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.779 0.220 0.000
Z97 Presence of other devices
0.779 0.221 0.000
C77.2 Intra-abdominal lymph nodes
0.777 0.223 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.777 0.223 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.776 0.224 0.000
C18 Malignant neoplasm of colon
0.776 0.224 0.000
M06 Other rheumatoid arthritis
0.776 0.224 0.000
M19 Other arthrosis
0.773 0.227 0.000
J32 Chronic sinusitis
0.772 0.228 0.000
N19 Unspecified renal failure
0.772 0.228 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.772 0.228 0.000
S90-S99 Injuries to the ankle and foot
0.771 0.229 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.770 0.230 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.770 0.230 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.770 0.230 0.000
C50.4 Upper-outer quadrant of breast
0.768 0.231 0.000
T40.2 Other opioids
0.768 0.232 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.768 0.232 0.000
N60-N64 Disorders of breast
0.768 0.232 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.765 0.235 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.764 0.235 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.764 0.236 0.000
Z86.0 Personal history of other neoplasms
0.764 0.236 0.000
C15 Malignant neoplasm of oesophagus
0.762 0.238 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.762 0.238 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.761 0.239 0.000
Z90.0 Acquired absence of part of head and neck
0.760 0.240 0.000
Z94.0 Kidney transplant status
0.757 0.243 0.000
S20-S29 Injuries to the thorax
0.757 0.243 0.000
Y43.3 Other antineoplastic drugs
0.756 0.244 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.755 0.245 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.753 0.247 0.000
F41.2 Mixed anxiety and depressive disorder
0.753 0.247 0.000
M54.59 Low back pain (Site unspecified)
0.750 0.250 0.000
F41.1 Generalised anxiety disorder
0.747 0.253 0.000
X60-X84 Intentional self-harm
0.746 0.254 0.000
C50.3 Lower-inner quadrant of breast
0.746 0.254 0.000
J33 Nasal polyp
0.745 0.255 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.745 0.255 0.000
J98.8 Other specified respiratory disorders
0.744 0.256 0.000
Y84.8 Other medical procedures
0.741 0.259 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.740 0.260 0.000
I80 Phlebitis and thrombophlebitis
0.740 0.260 0.000
Z88.5 Personal history of allergy to narcotic agent
0.740 0.260 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.740 0.260 0.000
G43 Migraine
0.738 0.262 0.000
M54.56 Low back pain (Lumbar region)
0.738 0.262 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.736 0.264 0.000
I34.1 Mitral (valve) prolapse
0.736 0.264 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.736 0.264 0.000
S80-S89 Injuries to the knee and lower leg
0.735 0.265 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.732 0.267 0.000
M71 Other bursopathies
0.732 0.268 0.000
C51-C58 Malignant neoplasms of female genital organs
0.730 0.270 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.729 0.271 0.000
C80 Malignant neoplasm without specification of site
0.728 0.271 0.000
F43 Reaction to severe stress, and adjustment disorders
0.728 0.272 0.000
I49 Other cardiac arrhythmias
0.727 0.273 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.727 0.273 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.725 0.275 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.724 0.275 0.000
I50 Heart failure
0.724 0.276 0.000
Z87 Personal history of other diseases and conditions
0.724 0.276 0.000
M22 Disorders of patella
0.724 0.276 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.723 0.277 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.722 0.278 0.000
M40-M43 Deforming dorsopathies
0.720 0.279 0.000
I60-I69 Cerebrovascular diseases
0.720 0.280 0.000
F45 Somatoform disorders
0.719 0.280 0.000
M54.4 Lumbago with sciatica
0.719 0.281 0.000
M79.64 Pain in limb (Hand)
0.719 0.281 0.000
V20-V29 Motorcycle rider injured in transport accident
0.718 0.282 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.717 0.283 0.000
M06.9 Rheumatoid arthritis, unspecified
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.717 0.283 0.000
D70 Agranulocytosis
0.717 0.283 0.000
F60 Specific personality disorders
0.717 0.283 0.000
I44 Atrioventricular and left bundle-branch block
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
M79.5 Residual foreign body in soft tissue
0.714 0.286 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.714 0.286 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.714 0.286 0.000
M19.0 Primary arthrosis of other joints
0.713 0.287 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
G90-G99 Other disorders of the nervous system
0.712 0.288 0.000
M79.62 Pain in limb (Upper arm)
0.711 0.289 0.000
M45-M49 Spondylopathies
0.711 0.289 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.711 0.289 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.711 0.289 0.000
C78.0 Secondary malignant neoplasm of lung
0.711 0.289 0.000
J17 Pneumonia in diseases classified elsewhere
0.710 0.290 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.710 0.290 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.710 0.290 0.000
J12 Viral pneumonia, not elsewhere classified
0.710 0.290 0.000
J11 Influenza, virus not identified
0.710 0.290 0.000
J10 Influenza due to identified influenza virus
0.710 0.290 0.000
J14 Pneumonia due to Haemophilus influenzae
0.710 0.290 0.000
J09 Influenza due to certain identified influenza virus
0.710 0.290 0.000
Z94.8 Other transplanted organ and tissue status
0.709 0.291 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.709 0.291 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.708 0.292 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.708 0.292 0.000
F80-F89 Disorders of psychological development
0.708 0.292 0.000
F70-F79 Mental retardation
0.708 0.292 0.000
C50.6 Axillary tail of breast
0.707 0.293 0.000
C50.0 Nipple and areola
0.707 0.293 0.000
W20-W49 Exposure to inanimate mechanical forces
0.706 0.293 0.000
Y40 Systemic antibiotics
0.706 0.294 0.000
H60-H62 Diseases of external ear
0.706 0.294 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.706 0.294 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.706 0.294 0.000
T81.9 Unspecified complication of procedure
0.706 0.294 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.706 0.294 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.706 0.294 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.706 0.294 0.000
J18.8 Other pneumonia, organism unspecified
0.705 0.295 0.000
J18.2 Hypostatic pneumonia, unspecified
0.705 0.295 0.000
J18.0 Bronchopneumonia, unspecified
0.705 0.295 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.704 0.296 0.000
J96 Respiratory failure, not elsewhere classified
0.704 0.296 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.704 0.296 0.000
M79.63 Pain in limb (Forearm)
0.704 0.296 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.702 0.298 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.701 0.299 0.000
F48 Other neurotic disorders
0.701 0.299 0.000
F44 Dissociative [conversion] disorders
0.701 0.299 0.000
F42 Obsessive-compulsive disorder
0.701 0.299 0.000
M79.10 Myalgia (Multiple sites)
0.701 0.299 0.000
I08 Multiple valve diseases
0.700 0.300 0.000
Y84.1 Kidney dialysis
0.700 0.300 0.000
Z90.8 Acquired absence of other organs
0.700 0.300 0.000
Y83.6 Removal of other organ (partial) (total)
0.699 0.301 0.000
H65-H75 Diseases of middle ear and mastoid
0.698 0.302 0.000
N64 Other disorders of breast
0.698 0.302 0.000
Z88.6 Personal history of allergy to analgesic agent
0.698 0.302 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.697 0.303 0.000
C16 Malignant neoplasm of stomach
0.696 0.304 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.696 0.304 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.696 0.304 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.696 0.304 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.696 0.304 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.696 0.304 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.696 0.304 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.696 0.304 0.000
F41.8 Other specified anxiety disorders
0.695 0.305 0.000
F41.3 Other mixed anxiety disorders
0.695 0.305 0.000
J98.9 Respiratory disorder, unspecified
0.695 0.305 0.000
J98.6 Disorders of diaphragm
0.695 0.305 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.695 0.305 0.000
J98.3 Compensatory emphysema
0.695 0.305 0.000
J98.2 Interstitial emphysema
0.695 0.305 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.695 0.305 0.000
Q60-Q64 Congenital malformations of the urinary system
0.694 0.306 0.000
C77.1 Intrathoracic lymph nodes
0.694 0.306 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.693 0.307 0.000
C77.0 Lymph nodes of head, face and neck
0.693 0.307 0.000
I35 Nonrheumatic aortic valve disorders
0.692 0.308 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.692 0.308 0.000
Z83 Family history of other specific disorders
0.691 0.309 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.691 0.309 0.000
M79.18 Myalgia (Other)
0.689 0.311 0.000
I82 Other venous embolism and thrombosis
0.689 0.311 0.000
M31 Other necrotising vasculopathies
0.688 0.312 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.688 0.312 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.687 0.313 0.000
M34 Systemic sclerosis
0.687 0.313 0.000
M33 Dermatopolymyositis
0.687 0.313 0.000
M32 Systemic lupus erythematosus
0.687 0.313 0.000
M30 Polyarteritis nodosa and related conditions
0.687 0.313 0.000
M21 Other acquired deformities of limbs
0.687 0.313 0.000
C77.8 Lymph nodes of multiple regions
0.687 0.313 0.000
C77.4 Inguinal and lower limb lymph nodes
0.687 0.313 0.000
J90 Pleural effusion, not elsewhere classified
0.687 0.313 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.686 0.314 0.000
G43.9 Migraine, unspecified
0.686 0.314 0.000
F40 Phobic anxiety disorders
0.684 0.316 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.684 0.316 0.000
M77 Other enthesopathies
0.683 0.317 0.000
M76 Enthesopathies of lower limb, excluding foot
0.683 0.317 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.683 0.317 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.682 0.317 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.682 0.317 0.000
H83 Other diseases of inner ear
0.682 0.318 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.681 0.319 0.000
I83 Varicose veins of lower extremities
0.681 0.319 0.000
M79.19 Myalgia (Site unspecified)
0.680 0.320 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.680 0.320 0.000
M35.3 Polymyalgia rheumatica
0.679 0.321 0.000
M53 Other dorsopathies, not elsewhere classified
0.679 0.321 0.000
M50.2 Other cervical disk displacement
0.679 0.321 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.678 0.322 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.678 0.322 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.678 0.322 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.678 0.322 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.678 0.322 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.678 0.322 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.678 0.322 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.678 0.322 0.000
T36 Poisoning by systemic antibiotics
0.678 0.322 0.000
M20.3 Other deformity of hallux (acquired)
0.677 0.322 0.000
M20.0 Deformity of finger(s)
0.677 0.322 0.000
M89 Other disorders of bone
0.677 0.323 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.675 0.325 0.000
M79.9 Soft tissue disorder, unspecified
0.675 0.325 0.000
M79.7 Fibromyalgia
0.675 0.325 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.675 0.325 0.000
M79.3 Panniculitis, unspecified
0.675 0.325 0.000
M79.2 Neuralgia and neuritis, unspecified
0.675 0.325 0.000
M20.4 Other hammer toe(s) (acquired)
0.672 0.328 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.671 0.329 0.000
H90 Conductive and sensorineural hearing loss
0.669 0.331 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.669 0.331 0.000
M50.0 Cervical disk disorder with myelopathy
0.668 0.332 0.000
Z90.3 Acquired absence of part of stomach
0.668 0.332 0.000
M35.0 Sicca syndrome [Sjogren]
0.668 0.332 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.668 0.332 0.000
C50.5 Lower-outer quadrant of breast
0.667 0.333 0.000
N00-N08 Glomerular diseases
0.665 0.334 0.000
I00-I02 Acute rheumatic fever
0.665 0.335 0.000
C50.8 Overlapping lesion of breast
0.664 0.336 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.664 0.336 0.000
I44.7 Left bundle-branch block, unspecified
0.664 0.336 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.663 0.337 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.663 0.337 0.000
J60-J70 Lung diseases due to external agents
0.663 0.337 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.663 0.337 0.000
D80-D89 Certain disorders involving the immune mechanism
0.663 0.337 0.000
Z22 Carrier of infectious disease
0.662 0.338 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.662 0.338 0.000
S70-S79 Injuries to the hip and thigh
0.660 0.339 0.000
C71 Malignant neoplasm of brain
0.659 0.341 0.000
C77.9 Lymph node, unspecified
0.659 0.341 0.000
M51 Other intervertebral disk disorders
0.658 0.342 0.000
J22 Unspecified acute lower respiratory infection
0.657 0.343 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.657 0.343 0.000
T86.1 Kidney transplant failure and rejection
0.657 0.343 0.000
Z93.5 Cystostomy status
0.656 0.344 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.655 0.345 0.000
J81 Pulmonary oedema
0.655 0.345 0.000
C77.5 Intrapelvic lymph nodes
0.654 0.346 0.000
T18 Foreign body in alimentary tract
0.653 0.347 0.000
J32.8 Other chronic sinusitis
0.653 0.347 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.653 0.347 0.000
M19.9 Arthrosis, unspecified
0.653 0.347 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.653 0.347 0.000
C50.2 Upper-inner quadrant of breast
0.652 0.348 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.652 0.348 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.652 0.348 0.000
Y84.2 Radiological procedure and radiotherapy
0.652 0.348 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.651 0.348 0.000
Y59 Other and unspecified vaccines and biological substances
0.651 0.348 0.000
Y58 Bacterial vaccines
0.651 0.348 0.000
Y57 Other and unspecified drugs and medicaments
0.651 0.348 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.651 0.348 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.651 0.348 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.651 0.348 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.651 0.348 0.000
Y52 Agents primarily affecting the cardiovascular system
0.651 0.348 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.651 0.348 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.651 0.348 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.651 0.348 0.000
Y48 Anaesthetics and therapeutic gases
0.651 0.348 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.651 0.348 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.651 0.348 0.000
Y44 Agents primarily affecting blood constituents
0.651 0.348 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.651 0.348 0.000
N25-N29 Other disorders of kidney and ureter
0.652 0.348 0.000
I50.0 Congestive heart failure
0.651 0.349 0.000
Z90.5 Acquired absence of kidney
0.651 0.349 0.000
M50.3 Other cervical disk degeneration
0.651 0.349 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.650 0.350 0.000
N99-N99 Other disorders of the genitourinary system
0.650 0.350 0.000
M18 Arthrosis of first carpometacarpal joint
0.649 0.351 0.000
E50-E64 Other nutritional deficiencies
0.649 0.351 0.000
Z98.1 Arthrodesis status
0.648 0.352 0.000
M79.67 Pain in limb (Ankle and foot)
0.648 0.352 0.000
M79.0 Rheumatism, unspecified
0.648 0.352 0.000
N64.5 Other signs and symptoms in breast
0.648 0.352 0.000
I31 Other diseases of pericardium
0.648 0.352 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.647 0.353 0.000
S40-S49 Injuries to the shoulder and upper arm
0.647 0.353 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.646 0.354 0.000
C09 Malignant neoplasm of tonsil
0.646 0.354 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.645 0.355 0.000
M79.60 Pain in limb (Multiple sites)
0.644 0.356 0.000
C18.4 Transverse colon
0.644 0.356 0.000
D72 Other disorders of white blood cells
0.644 0.356 0.000
V10-V19 Pedal cyclist injured in transport accident
0.644 0.356 0.000
M54.2 Cervicalgia
0.643 0.357 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.643 0.357 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.643 0.357 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.643 0.357 0.000
C21 Malignant neoplasm of anus and anal canal
0.643 0.357 0.000
C17 Malignant neoplasm of small intestine
0.643 0.357 0.000
C23 Malignant neoplasm of gallbladder
0.643 0.357 0.000
G70-G73 Diseases of myoneural junction and muscle
0.642 0.358 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.642 0.358 0.000
F99 Mental disorder, not otherwise specified
0.641 0.359 0.000
N20-N23 Urolithiasis
0.641 0.359 0.000
J33.9 Nasal polyp, unspecified
0.640 0.359 0.000
J80 Adult respiratory distress syndrome
0.640 0.360 0.000
C01 Malignant neoplasm of base of tongue
0.639 0.360 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.638 0.362 0.000
M24 Other specific joint derangements
0.638 0.362 0.000
M65-M68 Disorders of synovium and tendon
0.638 0.362 0.000
I45 Other conduction disorders
0.638 0.362 0.000
J32.9 Chronic sinusitis, unspecified
0.637 0.363 0.000
I81 Portal vein thrombosis
0.636 0.363 0.000
I52 Other heart disorders in diseases classified elsewhere
0.636 0.364 0.000
I48 Atrial fibrillation and flutter
0.636 0.364 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.636 0.364 0.000
I41 Myocarditis in diseases classified elsewhere
0.636 0.364 0.000
I40 Acute myocarditis
0.636 0.364 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.636 0.364 0.000
I37 Pulmonary valve disorders
0.636 0.364 0.000
I36 Nonrheumatic tricuspid valve disorders
0.636 0.364 0.000
I33 Acute and subacute endocarditis
0.636 0.364 0.000
I32 Pericarditis in diseases classified elsewhere
0.636 0.364 0.000
I30 Acute pericarditis
0.636 0.364 0.000
G35 Multiple sclerosis
0.636 0.364 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.636 0.364 0.000
C15.9 Oesophagus, unspecified
0.635 0.365 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.635 0.365 0.000
J00-J06 Acute upper respiratory infections
0.635 0.365 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.635 0.365 0.000
L20-L30 Dermatitis and eczema
0.632 0.368 0.000
T68 Hypothermia
0.632 0.368 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.632 0.368 0.000
E70-E90 Metabolic disorders
0.632 0.368 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.632 0.368 0.000
Z94.7 Corneal transplant status
0.632 0.368 0.000
Z94.6 Bone transplant status
0.632 0.368 0.000
Z94.5 Skin transplant status
0.632 0.368 0.000
Z94.4 Liver transplant status
0.632 0.368 0.000
Z94.3 Heart and lungs transplant status
0.632 0.368 0.000
Z94.2 Lung transplant status
0.632 0.368 0.000
Z94.1 Heart transplant status
0.632 0.368 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.631 0.369 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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