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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117577998
log Bayes Factor = 13.0097
Chromosome 8   position 143,505,653  (GRCh37) Explore rs117577998 on Ensembl!
Variant rs117577998 is part of Cluster X0052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.995 0.005 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.994 0.006 0.000
G43.9 Migraine, unspecified
0.994 0.006 0.000
G43 Migraine
0.993 0.007 0.000
G40-G47 Episodic and paroxysmal disorders
0.993 0.007 0.000
M50-M54 Other dorsopathies
0.991 0.009 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.990 0.010 0.000
M54.5 Low back pain
0.990 0.010 0.000
M70-M79 Other soft tissue disorders
0.990 0.010 0.000
M54 Dorsalgia
0.989 0.011 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.989 0.011 0.000
L57.0 Actinic keratosis
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.985 0.015 0.000
E00-E07 Disorders of thyroid gland
0.984 0.016 0.000
M54.56 Low back pain (Lumbar region)
0.984 0.016 0.000
E03 Other hypothyroidism
0.982 0.018 0.000
M05-M14 Inflammatory polyarthropathies
0.981 0.019 0.000
N30-N39 Other diseases of urinary system
0.981 0.019 0.000
Chapter XIV Diseases of the genitourinary system
0.981 0.019 0.000
E03.9 Hypothyroidism, unspecified
0.980 0.020 0.000
N30 Cystitis
0.975 0.025 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.974 0.026 0.000
M06 Other rheumatoid arthritis
0.958 0.042 0.000
M54.57 Low back pain (Lumbosacral region)
0.958 0.042 0.000
E20-E35 Disorders of other endocrine glands
0.958 0.042 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.956 0.044 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.950 0.050 0.000
N17-N19 Renal failure
0.949 0.051 0.000
Chapter XX External causes of morbidity and mortality
0.948 0.052 0.000
Chapter I Certain infectious and parasitic diseases
0.947 0.053 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.940 0.060 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.938 0.062 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.937 0.063 0.000
L40-L45 Papulosquamous disorders
0.937 0.063 0.000
M06.9 Rheumatoid arthritis, unspecified
0.928 0.072 0.000
G30-G32 Other degenerative diseases of the nervous system
0.921 0.079 0.000
E50-E64 Other nutritional deficiencies
0.921 0.079 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.914 0.086 0.000
N30.8 Other cystitis
0.908 0.092 0.000
S00-S09 Injuries to the head
0.900 0.100 0.000
L40 Psoriasis
0.900 0.100 0.000
O36 Maternal care for other known or suspected foetal problems
0.899 0.101 0.000
N19 Unspecified renal failure
0.898 0.102 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.897 0.103 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.896 0.104 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.895 0.105 0.000
O30 Multiple gestation
0.892 0.108 0.000
N99-N99 Other disorders of the genitourinary system
0.890 0.110 0.000
M75 Shoulder lesions
0.889 0.111 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.888 0.112 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.888 0.112 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.885 0.115 0.000
L81 Other disorders of pigmentation
0.885 0.115 0.000
N30.9 Cystitis, unspecified
0.884 0.116 0.000
S50-S59 Injuries to the elbow and forearm
0.883 0.117 0.000
O85-O92 Complications predominantly related to the puerperium
0.877 0.123 0.000
M07 Psoriatic and enteropathic arthropathies
0.876 0.124 0.000
M45-M49 Spondylopathies
0.873 0.127 0.000
E53 Deficiency of other B group vitamins
0.869 0.131 0.000
T39.1 4-Aminophenol derivatives
0.866 0.134 0.000
O32.1 Maternal care for breech presentation
0.864 0.136 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.860 0.139 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.857 0.143 0.000
W00-W19 Falls
0.854 0.146 0.000
N30.2 Other chronic cystitis
0.853 0.147 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.851 0.149 0.000
M75.0 Adhesive capsulitis of shoulder
0.848 0.152 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.847 0.153 0.000
Q60-Q64 Congenital malformations of the urinary system
0.845 0.155 0.000
B95-B98 Bacterial, viral and other infectious agents
0.844 0.156 0.000
L40.5 Arthropathic psoriasis
0.843 0.157 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.841 0.159 0.000
N35 Urethral stricture
0.839 0.161 0.000
O80-O84 Delivery
0.839 0.161 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.838 0.162 0.000
O23 Infections of genito-urinary tract in pregnancy
0.834 0.166 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.834 0.166 0.000
O20 Haemorrhage in early pregnancy
0.833 0.166 0.000
G70-G73 Diseases of myoneural junction and muscle
0.832 0.168 0.000
E53.8 Deficiency of other specified B group vitamins
0.832 0.168 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.830 0.170 0.000
M86-M90 Other osteopathies
0.827 0.173 0.000
E34 Other endocrine disorders
0.826 0.174 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.825 0.175 0.000
E22 Hyperfunction of pituitary gland
0.825 0.175 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.824 0.176 0.000
S56 Injury of muscle and tendon at forearm level
0.822 0.178 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.821 0.179 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.820 0.180 0.000
O30.0 Twin pregnancy
0.819 0.181 0.000
X60-X84 Intentional self-harm
0.819 0.181 0.000
O16 Unspecified maternal hypertension
0.819 0.181 0.000
M54.9 Dorsalgia, unspecified
0.817 0.183 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.817 0.183 0.000
L81.4 Other melanin hyperpigmentation
0.816 0.184 0.000
S06 Intracranial injury
0.814 0.186 0.000
N30.3 Trigonitis
0.813 0.187 0.000
M72 Fibroblastic disorders
0.812 0.188 0.000
L80 Vitiligo
0.810 0.190 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.810 0.190 0.000
B07 Viral warts
0.809 0.191 0.000
N18 Chronic renal failure
0.807 0.193 0.000
E27 Other disorders of adrenal gland
0.806 0.194 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.806 0.194 0.000
G20-G26 Extrapyramidal and movement disorders
0.805 0.195 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.804 0.196 0.000
M71 Other bursopathies
0.804 0.196 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.803 0.197 0.000
M07.3 Other psoriatic arthropathies
0.802 0.198 0.000
O00-O08 Pregnancy with abortive outcome
0.798 0.202 0.000
S10-S19 Injuries to the neck
0.796 0.204 0.000
M65-M68 Disorders of synovium and tendon
0.795 0.205 0.000
M54.55 Low back pain (Thoracolumbar region)
0.794 0.206 0.000
N36 Other disorders of urethra
0.791 0.209 0.000
N25-N29 Other disorders of kidney and ureter
0.789 0.211 0.000
O43 Placental disorders
0.786 0.214 0.000
M06.4 Inflammatory polyarthropathy
0.784 0.215 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.784 0.216 0.000
E23 Hypofunction and other disorders of pituitary gland
0.780 0.220 0.000
L50-L54 Urticaria and erythema
0.780 0.220 0.000
T66-T78 Other and unspecified effects of external causes
0.777 0.223 0.000
M54.50 Low back pain (Multiple sites in spine)
0.776 0.224 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.775 0.225 0.000
Q61 Cystic kidney disease
0.774 0.226 0.000
O21 Excessive vomiting in pregnancy
0.774 0.226 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.773 0.227 0.000
V98-V99 Other and unspecified transport accidents
0.772 0.228 0.000
O40 Polyhydramnios
0.772 0.228 0.000
G41 Status epilepticus
0.771 0.229 0.000
L83 Acanthosis nigricans
0.771 0.229 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.770 0.230 0.000
A00-A09 Intestinal infectious diseases
0.770 0.230 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.770 0.230 0.000
L89 Decubitus ulcer
0.768 0.232 0.000
M40-M43 Deforming dorsopathies
0.768 0.232 0.000
L93 Lupus erythematosus
0.766 0.234 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.765 0.235 0.000
G90-G99 Other disorders of the nervous system
0.764 0.236 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.763 0.236 0.000
G43.8 Other migraine
0.758 0.241 0.000
Q80-Q89 Other congenital malformations
0.758 0.242 0.000
G31.8 Other specified degenerative diseases of nervous system
0.757 0.243 0.000
E03.8 Other specified hypothyroidism
0.754 0.246 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.754 0.246 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.754 0.246 0.000
O36.8 Maternal care for other specified foetal problems
0.753 0.247 0.000
M48 Other spondylopathies
0.753 0.247 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.752 0.248 0.000
L91 Hypertrophic disorders of skin
0.752 0.248 0.000
O86 Other puerperal infections
0.751 0.248 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.750 0.250 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.749 0.251 0.000
O32.2 Maternal care for transverse and oblique lie
0.749 0.251 0.000
G44 Other headache syndromes
0.749 0.251 0.000
M89 Other disorders of bone
0.747 0.252 0.000
M70.2 Olecranon bursitis
0.745 0.254 0.000
M10 Gout
0.744 0.256 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.744 0.256 0.000
G43.1 Migraine with aura [classical migraine]
0.744 0.256 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.742 0.258 0.000
M53 Other dorsopathies, not elsewhere classified
0.742 0.258 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.741 0.259 0.000
N30.4 Irradiation cystitis
0.740 0.260 0.000
B15-B19 Viral hepatitis
0.740 0.260 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.739 0.260 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.739 0.261 0.000
E06 Thyroiditis
0.738 0.262 0.000
N35.9 Urethral stricture, unspecified
0.738 0.262 0.000
M75.4 Impingement syndrome of shoulder
0.737 0.263 0.000
M79.0 Rheumatism, unspecified
0.737 0.263 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.735 0.265 0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level
0.734 0.266 0.000
M77 Other enthesopathies
0.734 0.266 0.000
L40.9 Psoriasis, unspecified
0.734 0.266 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.732 0.267 0.000
O42 Premature rupture of membranes
0.732 0.268 0.000
E34.9 Endocrine disorder, unspecified
0.732 0.268 0.000
T79-T79 Certain early complications of trauma
0.732 0.268 0.000
S00 Superficial injury of head
0.730 0.270 0.000
M79.6 Pain in limb
0.729 0.271 0.000
O44 Placenta praevia
0.729 0.271 0.000
E22.0 Acromegaly and pituitary gigantism
0.728 0.272 0.000
G12 Spinal muscular atrophy and related syndromes
0.728 0.272 0.000
M06.0 Seronegative rheumatoid arthritis
0.727 0.273 0.000
N30.1 Interstitial cystitis (chronic)
0.727 0.273 0.000
M54.1 Radiculopathy
0.727 0.273 0.000
O32.8 Maternal care for other malpresentation of foetus
0.727 0.273 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.724 0.276 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.723 0.277 0.000
N17 Acute renal failure
0.723 0.277 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.720 0.280 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.719 0.281 0.000
O36.5 Maternal care for poor foetal growth
0.719 0.281 0.000
L85 Other epidermal thickening
0.719 0.281 0.000
T14 Injury of unspecified body region
0.719 0.281 0.000
O41 Other disorders of amniotic fluid and membranes
0.718 0.282 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.718 0.282 0.000
O34.4 Maternal care for other abnormalities of cervix
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
L10-L14 Bullous disorders
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
L40.0 Psoriasis vulgaris
0.716 0.283 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.716 0.284 0.000
S06.5 Traumatic subdural haemorrhage
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
N34 Urethritis and urethral syndrome
0.714 0.286 0.000
O45 Premature separation of placenta [abruptio placentae]
0.713 0.286 0.000
O33 Maternal care for known or suspected disproportion
0.713 0.286 0.000
O31 Complications specific to multiple gestation
0.713 0.286 0.000
G20 Parkinson's disease
0.713 0.287 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.713 0.287 0.000
L58 Radiodermatitis
0.713 0.287 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.713 0.287 0.000
L55 Sunburn
0.713 0.287 0.000
G43.3 Complicated migraine
0.712 0.288 0.000
G43.2 Status migrainosus
0.712 0.288 0.000
G43.0 Migraine without aura [common migraine]
0.712 0.288 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.712 0.288 0.000
E07 Other disorders of thyroid
0.712 0.288 0.000
S51 Open wound of forearm
0.710 0.290 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.710 0.290 0.000
L57.5 Actinic granuloma
0.710 0.290 0.000
L57.4 Cutis laxa senilis
0.710 0.290 0.000
L57.3 Poikiloderma of Civatte
0.710 0.290 0.000
L57.2 Cutis rhomboidalis nuchae
0.710 0.290 0.000
L57.1 Actinic reticuloid
0.710 0.290 0.000
E29 Testicular dysfunction
0.710 0.290 0.000
M54.54 Low back pain-Thoracic
0.710 0.290 0.000
M54.53 Low back pain-Cervicothoracic
0.710 0.290 0.000
M54.52 Low back pain-Cervical
0.710 0.290 0.000
M54.51 Low back pain-Occipit-atl-axl
0.710 0.290 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.709 0.290 0.000
M54.8 Other dorsalgia
0.709 0.290 0.000
M54.0 Panniculitis affecting regions of neck and back
0.709 0.290 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.709 0.291 0.000
L94 Other localised connective tissue disorders
0.709 0.291 0.000
L87 Transepidermal elimination disorders
0.709 0.291 0.000
L88 Pyoderma gangrenosum
0.709 0.291 0.000
L86 Keratoderma in diseases classified elsewhere
0.709 0.291 0.000
M05 Seropositive rheumatoid arthritis
0.708 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.708 0.292 0.000
Chapter VIII Diseases of the ear and mastoid process
0.707 0.293 0.000
Q50-Q56 Congenital malformations of genital organs
0.707 0.293 0.000
T33-T35 Frostbite
0.706 0.294 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.706 0.294 0.000
T00-T07 Injuries involving multiple body regions
0.706 0.294 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.706 0.294 0.000
E00 Congenital iodine-deficiency syndrome
0.706 0.294 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.706 0.294 0.000
M54.59 Low back pain (Site unspecified)
0.706 0.294 0.000
S05 Injury of eye and orbit
0.704 0.296 0.000
E03.5 Myxoedema coma
0.704 0.296 0.000
E03.4 Atrophy of thyroid (acquired)
0.704 0.296 0.000
E03.3 Postinfectious hypothyroidism
0.704 0.296 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.704 0.296 0.000
E03.1 Congenital hypothyroidism without goitre
0.704 0.296 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.704 0.296 0.000
M12 Other specific arthropathies
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.703 0.297 0.000
M08 Juvenile arthritis
0.703 0.297 0.000
N37 Urethral disorders in diseases classified elsewhere
0.703 0.297 0.000
N33 Bladder disorders in diseases classified elsewhere
0.703 0.297 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
M75.5 Bursitis of shoulder
0.702 0.298 0.000
S90-S99 Injuries to the ankle and foot
0.702 0.298 0.000
M79.7 Fibromyalgia
0.702 0.298 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.702 0.298 0.000
M11 Other crystal arthropathies
0.700 0.300 0.000
A80-A89 Viral infections of the central nervous system
0.700 0.300 0.000
E10-E14 Diabetes mellitus
0.699 0.301 0.000
N18.0 End-stage renal disease
0.699 0.301 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.699 0.301 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.698 0.301 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.698 0.302 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.302 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.698 0.302 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.698 0.302 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.698 0.302 0.000
T36 Poisoning by systemic antibiotics
0.698 0.302 0.000
M76 Enthesopathies of lower limb, excluding foot
0.698 0.302 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.697 0.303 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.697 0.303 0.000
W17 Other fall from one level to another
0.697 0.303 0.000
W18 Other fall on same level
0.697 0.303 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.696 0.304 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.694 0.306 0.000
O60-O75 Complications of labour and delivery
0.694 0.306 0.000
W10 Fall on and from stairs and steps
0.694 0.306 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.692 0.308 0.000
G30 Alzheimer's disease
0.691 0.308 0.000
E24 Cushing's syndrome
0.691 0.308 0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level
0.691 0.309 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.691 0.309 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.690 0.310 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.690 0.310 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.690 0.310 0.000
N30.0 Acute cystitis
0.689 0.311 0.000
O81 Single delivery by forceps and vacuum extractor
0.687 0.313 0.000
M06.8 Other specified rheumatoid arthritis
0.687 0.313 0.000
M06.3 Rheumatoid nodule
0.687 0.313 0.000
M06.2 Rheumatoid bursitis
0.687 0.313 0.000
M06.1 Adult-onset Still's disease
0.687 0.313 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.687 0.313 0.000
E32 Diseases of thymus
0.687 0.313 0.000
E31 Polyglandular dysfunction
0.687 0.313 0.000
E30 Disorders of puberty, not elsewhere classified
0.687 0.313 0.000
E26 Hyperaldosteronism
0.687 0.313 0.000
E25 Adrenogenital disorders
0.687 0.313 0.000
E20 Hypoparathyroidism
0.687 0.313 0.000
M49 Spondylopathies in diseases classified elsewhere
0.686 0.314 0.000
O29 Complications of anaesthesia during pregnancy
0.685 0.315 0.000
O28 Abnormal findings on antenatal screening of mother
0.685 0.315 0.000
O22 Venous complications in pregnancy
0.685 0.315 0.000
O25 Malnutrition in pregnancy
0.685 0.315 0.000
O34.1 Maternal care for tumour of corpus uteri
0.685 0.315 0.000
M79.8 Other specified soft tissue disorders
0.684 0.316 0.000
O80 Single spontaneous delivery
0.684 0.316 0.000
V40-V49 Car occupant injured in transport accident
0.683 0.317 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.683 0.317 0.000
M91-M94 Chondropathies
0.682 0.317 0.000
M70.22 Olecranon bursitis-Upper arm
0.682 0.318 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.681 0.319 0.000
T39.4 Antirheumatics, not elsewhere classified
0.681 0.319 0.000
T39.2 Pyrazolone derivatives
0.681 0.319 0.000
E22.1 Hyperprolactinaemia
0.681 0.319 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.680 0.320 0.000
Y35-Y36 Legal intervention and operations of war
0.680 0.320 0.000
Y10-Y34 Event of undetermined intent
0.680 0.320 0.000
X85-X99 Assault
0.680 0.320 0.000
X30-X39 Exposure to forces of nature
0.680 0.320 0.000
X20-X29 Contact with venomous animals and plants
0.680 0.320 0.000
X10-X19 Contact with heat and hot substances
0.680 0.320 0.000
X00-X09 Exposure to smoke, fire and flames
0.680 0.320 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.680 0.320 0.000
W75-W84 Other accidental threats to breathing
0.680 0.320 0.000
W65-W74 Accidental drowning and submersion
0.680 0.320 0.000
W50-W64 Exposure to animate mechanical forces
0.680 0.320 0.000
V95-V97 Air and space transport accidents
0.680 0.320 0.000
V90-V94 Water transport accidents
0.680 0.320 0.000
V70-V79 Bus occupant injured in transport accident
0.680 0.320 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.680 0.320 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.680 0.320 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.680 0.320 0.000
V01-V09 Pedestrian injured in transport accident
0.680 0.320 0.000
M79.2 Neuralgia and neuritis, unspecified
0.679 0.321 0.000
B99-B99 Other infectious diseases
0.679 0.321 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.679 0.321 0.000
B50-B64 Protozoal diseases
0.679 0.321 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.679 0.321 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.679 0.321 0.000
A75-A79 Rickettsioses
0.679 0.321 0.000
A70-A74 Other diseases caused by chlamydiae
0.679 0.321 0.000
A65-A69 Other spirochaetal diseases
0.679 0.321 0.000
A20-A28 Certain zoonotic bacterial diseases
0.679 0.321 0.000
A15-A19 Tuberculosis
0.679 0.321 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.679 0.321 0.000
O36.4 Maternal care for intra-uterine death
0.677 0.323 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.676 0.324 0.000
E61 Deficiency of other nutrient elements
0.676 0.324 0.000
E27.1 Primary adrenocortical insufficiency
0.675 0.325 0.000
G82 Paraplegia and tetraplegia
0.675 0.325 0.000
B65-B83 Helminthiases
0.674 0.326 0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy
0.674 0.326 0.000
M72.2 Plantar fascial fibromatosis
0.674 0.326 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.674 0.326 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.674 0.326 0.000
L82 Seborrhoeic keratosis
0.674 0.326 0.000
M54.3 Sciatica
0.673 0.326 0.000
M45 Ankylosing spondylitis
0.673 0.327 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.673 0.327 0.000
Q35-Q37 Cleft lip and cleft palate
0.673 0.327 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.673 0.327 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.673 0.327 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.672 0.327 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.672 0.328 0.000
O32.6 Maternal care for compound presentation
0.672 0.328 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.672 0.328 0.000
O32.4 Maternal care for high head at term
0.672 0.328 0.000
O32.3 Maternal care for face, brow and chin presentation
0.672 0.328 0.000
O32.0 Maternal care for unstable lie
0.672 0.328 0.000
L44 Other papulosquamous disorders
0.672 0.328 0.000
L41 Parapsoriasis
0.672 0.328 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.672 0.328 0.000
L42 Pityriasis rosea
0.672 0.328 0.000
S11 Open wound of neck
0.672 0.328 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.671 0.329 0.000
O02 Other abnormal products of conception
0.671 0.329 0.000
Y52 Agents primarily affecting the cardiovascular system
0.670 0.330 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.669 0.330 0.000
A30-A49 Other bacterial diseases
0.668 0.331 0.000
N18.5 Chronic kidney disease, stage 5
0.668 0.332 0.000
M79.1 Myalgia
0.668 0.332 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.668 0.332 0.000
M48.0 Spinal stenosis
0.667 0.333 0.000
L98.0 Pyogenic granuloma
0.667 0.333 0.000
E28 Ovarian dysfunction
0.667 0.333 0.000
Q61.2 Polycystic kidney, adult type
0.667 0.333 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.666 0.333 0.000
G71 Primary disorders of muscles
0.666 0.334 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.666 0.334 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.666 0.334 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.666 0.334 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.664 0.336 0.000
M41 Scoliosis
0.663 0.337 0.000
T92 Sequelae of injuries of upper limb
0.662 0.338 0.000
Q61.3 Polycystic kidney, unspecified
0.661 0.339 0.000
G70 Myasthenia gravis and other myoneural disorders
0.661 0.339 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.661 0.339 0.000
S02 Fracture of skull and facial bones
0.661 0.339 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.660 0.340 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.660 0.340 0.000
E63 Other nutritional deficiencies
0.660 0.340 0.000
E56 Other vitamin deficiencies
0.660 0.340 0.000
E51 Thiamine deficiency
0.660 0.340 0.000
E50 Vitamin A deficiency
0.660 0.340 0.000
E60 Dietary zinc deficiency
0.660 0.340 0.000
E59 Dietary selenium deficiency
0.660 0.340 0.000
E58 Dietary calcium deficiency
0.660 0.340 0.000
E54 Ascorbic acid deficiency
0.660 0.340 0.000
E52 Niacin deficiency [pellagra]
0.660 0.340 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.660 0.340 0.000
T39.0 Salicylates
0.658 0.342 0.000
S06.0 Concussion
0.657 0.343 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.657 0.343 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.656 0.344 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.656 0.344 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.655 0.345 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.655 0.345 0.000
L98.5 Mucinosis of skin
0.655 0.345 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.655 0.345 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.655 0.345 0.000
L98.1 Factitial dermatitis
0.655 0.345 0.000
G80 Infantile cerebral palsy
0.654 0.346 0.000
M89.9 Disorder of bone, unspecified
0.654 0.346 0.000
M75.3 Calcific tendinitis of shoulder
0.653 0.347 0.000
O24 Diabetes mellitus in pregnancy
0.652 0.348 0.000
O03 Spontaneous abortion
0.652 0.348 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.652 0.348 0.000
M46 Other inflammatory spondylopathies
0.651 0.349 0.000
S60-S69 Injuries to the wrist and hand
0.651 0.349 0.000
S01 Open wound of head
0.651 0.349 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.651 0.349 0.000
N36.1 Urethral diverticulum
0.650 0.350 0.000
O23.5 Infections of the genital tract in pregnancy
0.650 0.350 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.648 0.352 0.000
O26.8 Other specified pregnancy-related conditions
0.648 0.352 0.000
T90 Sequelae of injuries of head
0.648 0.352 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.647 0.353 0.000
G12.2 Motor neuron disease
0.647 0.353 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.647 0.353 0.000
V99 Unspecified transport accident
0.646 0.354 0.000
S08 Traumatic amputation of part of head
0.645 0.354 0.000
S07 Crushing injury of head
0.645 0.354 0.000
S04 Injury of cranial nerves
0.645 0.354 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.645 0.354 0.000
L40.8 Other psoriasis
0.645 0.355 0.000
L40.4 Guttate psoriasis
0.645 0.355 0.000
L40.3 Pustulosis palmaris et plantaris
0.645 0.355 0.000
L40.2 Acrodermatitis continua
0.645 0.355 0.000
L40.1 Generalised pustular psoriasis
0.645 0.355 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.645 0.355 0.000
G41.0 Grand mal status epilepticus
0.645 0.355 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.645 0.355 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.644 0.356 0.000
O36.2 Maternal care for hydrops foetalis
0.644 0.356 0.000
O36.1 Maternal care for other isoimmunisation
0.644 0.356 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.644 0.356 0.000
O21.9 Vomiting of pregnancy, unspecified
0.644 0.356 0.000
Q00-Q07 Congenital malformations of the nervous system
0.644 0.356 0.000
E27.2 Addisonian crisis
0.643 0.357 0.000
M79.9 Soft tissue disorder, unspecified
0.643 0.357 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.643 0.357 0.000
M79.3 Panniculitis, unspecified
0.643 0.357 0.000
V80-V89 Other land transport accidents
0.643 0.357 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.643 0.357 0.000
L92.0 Granuloma annulare
0.643 0.357 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.642 0.358 0.000
O97 Death from sequelae of direct obstetric causes
0.642 0.358 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.642 0.358 0.000
O95 Obstetric death of unspecified cause
0.642 0.358 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.642 0.358 0.000
O15 Eclampsia
0.642 0.358 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.642 0.358 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.640 0.360 0.000
O30.9 Multiple gestation, unspecified
0.640 0.360 0.000
O30.8 Other multiple gestation
0.640 0.360 0.000
O30.2 Quadruplet pregnancy
0.640 0.360 0.000
O30.1 Triplet pregnancy
0.640 0.360 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.640 0.360 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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