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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117588604
log Bayes Factor = 8.30479
Chromosome 6   position 82,768,899  (GRCh37) Explore rs117588604 on Ensembl!
Variant rs117588604 is part of Cluster X0261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
I20-I25 Ischaemic heart diseases
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.988 0.012 0.000
S00-S09 Injuries to the head
0.985 0.015 0.000
I25 Chronic ischaemic heart disease
0.983 0.017 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.977 0.023 0.000
I25.2 Old myocardial infarction
0.976 0.024 0.000
I30-I52 Other forms of heart disease
0.976 0.024 0.000
I34 Nonrheumatic mitral valve disorders
0.973 0.027 0.000
I34.0 Mitral (valve) insufficiency
0.971 0.029 0.000
M50-M54 Other dorsopathies
0.969 0.031 0.000
Chapter XX External causes of morbidity and mortality
0.969 0.031 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.966 0.034 0.000
I60-I69 Cerebrovascular diseases
0.962 0.038 0.000
M70-M79 Other soft tissue disorders
0.960 0.040 0.000
H53-H54 Visual disturbances and blindness
0.959 0.041 0.000
Chapter II Neoplasms
0.958 0.042 0.000
M51 Other intervertebral disk disorders
0.951 0.049 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.947 0.053 0.000
E10-E14 Diabetes mellitus
0.944 0.056 0.000
E70-E90 Metabolic disorders
0.941 0.059 0.000
I61 Intracerebral haemorrhage
0.940 0.060 0.000
S06 Intracranial injury
0.938 0.062 0.000
S90-S99 Injuries to the ankle and foot
0.935 0.065 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.932 0.068 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.932 0.068 0.000
S50-S59 Injuries to the elbow and forearm
0.930 0.070 0.000
E20-E35 Disorders of other endocrine glands
0.926 0.074 0.000
Chapter VI Diseases of the nervous system
0.924 0.076 0.000
E89.0 Postprocedural hypothyroidism
0.922 0.078 0.000
M80-M85 Disorders of bone density and structure
0.921 0.079 0.000
Chapter X Diseases of the respiratory system
0.916 0.084 0.000
I74 Arterial embolism and thrombosis
0.915 0.085 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.915 0.085 0.000
J30-J39 Other diseases of upper respiratory tract
0.915 0.085 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.914 0.086 0.000
J38.7 Other diseases of larynx
0.910 0.090 0.000
M72 Fibroblastic disorders
0.904 0.096 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.897 0.103 0.000
H02 Other disorders of eyelid
0.897 0.103 0.000
I42 Cardiomyopathy
0.897 0.103 0.000
I77 Other disorders of arteries and arterioles
0.894 0.106 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.893 0.107 0.000
C51-C58 Malignant neoplasms of female genital organs
0.888 0.112 0.000
H53 Visual disturbances
0.888 0.112 0.000
S20-S29 Injuries to the thorax
0.881 0.119 0.000
E10 Insulin-dependent diabetes mellitus
0.880 0.120 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.879 0.121 0.000
D41.4 Bladder
0.876 0.124 0.000
Chapter XIV Diseases of the genitourinary system
0.876 0.124 0.000
G90-G99 Other disorders of the nervous system
0.868 0.132 0.000
N10-N16 Renal tubulo-interstitial diseases
0.868 0.132 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.868 0.132 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.867 0.133 0.000
J39 Other diseases of upper respiratory tract
0.867 0.133 0.000
Q60-Q64 Congenital malformations of the urinary system
0.867 0.133 0.000
I21 Acute myocardial infarction
0.867 0.133 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.865 0.135 0.000
H04 Disorders of lachrymal system
0.865 0.135 0.000
M53 Other dorsopathies, not elsewhere classified
0.861 0.139 0.000
I42.9 Cardiomyopathy, unspecified
0.856 0.144 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.854 0.146 0.000
H54 Blindness and low vision
0.854 0.146 0.000
I45 Other conduction disorders
0.854 0.146 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.851 0.148 0.000
N13 Obstructive and reflux uropathy
0.848 0.152 0.000
I38 Endocarditis, valve unspecified
0.847 0.153 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.846 0.154 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.843 0.157 0.000
N17-N19 Renal failure
0.842 0.158 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.842 0.158 0.000
E11 Non-insulin-dependent diabetes mellitus
0.841 0.159 0.000
J38.3 Other diseases of vocal cords
0.837 0.163 0.000
S09 Other and unspecified injuries of head
0.836 0.164 0.000
H30-H36 Disorders of choroid and retina
0.835 0.165 0.000
M79.8 Other specified soft tissue disorders
0.835 0.165 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.831 0.169 0.000
H53.2 Diplopia
0.830 0.170 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.830 0.170 0.000
M80 Osteoporosis with pathological fracture
0.829 0.171 0.000
N18 Chronic renal failure
0.827 0.173 0.000
I78 Diseases of capillaries
0.827 0.173 0.000
H55-H59 Other disorders of eye and adnexa
0.825 0.175 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.823 0.177 0.000
M76 Enthesopathies of lower limb, excluding foot
0.823 0.177 0.000
I73 Other peripheral vascular diseases
0.823 0.177 0.000
S01 Open wound of head
0.821 0.179 0.000
S90 Superficial injury of ankle and foot
0.819 0.181 0.000
S51 Open wound of forearm
0.818 0.182 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.817 0.183 0.000
S91 Open wound of ankle and foot
0.816 0.184 0.000
I05-I09 Chronic rheumatic heart diseases
0.816 0.184 0.000
M86-M90 Other osteopathies
0.815 0.185 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.813 0.187 0.000
S00 Superficial injury of head
0.813 0.187 0.000
I22 Subsequent myocardial infarction
0.810 0.190 0.000
I72 Other aneurysm
0.808 0.192 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.808 0.192 0.000
S10-S19 Injuries to the neck
0.808 0.192 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.808 0.192 0.000
N25-N29 Other disorders of kidney and ureter
0.808 0.192 0.000
I25.1 Atherosclerotic heart disease
0.807 0.193 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.807 0.193 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.806 0.194 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.805 0.195 0.000
E86 Volume depletion
0.804 0.196 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.804 0.196 0.000
H02.9 Disorder of eyelid, unspecified
0.803 0.197 0.000
N13.3 Other and unspecified hydronephrosis
0.801 0.199 0.000
S06.3 Focal brain injury
0.801 0.199 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.801 0.199 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.800 0.200 0.000
M20-M25 Other joint disorders
0.798 0.202 0.000
E23 Hypofunction and other disorders of pituitary gland
0.796 0.204 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.794 0.205 0.000
W00-W19 Falls
0.794 0.206 0.000
J00-J06 Acute upper respiratory infections
0.793 0.207 0.000
J39.2 Other diseases of pharynx
0.793 0.207 0.000
C78.0 Secondary malignant neoplasm of lung
0.792 0.208 0.000
H01 Other inflammation of eyelid
0.791 0.209 0.000
I63 Cerebral infarction
0.791 0.209 0.000
E29 Testicular dysfunction
0.789 0.211 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.789 0.211 0.000
H05 Disorders of orbit
0.787 0.213 0.000
E10.3 With ophthalmic complications
0.783 0.217 0.000
Y60.0 During surgical operation
0.783 0.217 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.783 0.217 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.779 0.221 0.000
H53.4 Visual field defects
0.777 0.223 0.000
I73.9 Peripheral vascular disease, unspecified
0.777 0.223 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.777 0.223 0.000
T86 Failure and rejection of transplanted organs and tissues
0.775 0.225 0.000
H02.1 Ectropion of eyelid
0.774 0.226 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.773 0.227 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.773 0.227 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.772 0.228 0.000
I60 Subarachnoid haemorrhage
0.771 0.229 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.770 0.230 0.000
M51.9 Intervertebral disk disorder, unspecified
0.769 0.231 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.769 0.231 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.768 0.232 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.767 0.233 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.766 0.234 0.000
H54.0 Blindness, both eyes
0.766 0.234 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.765 0.235 0.000
E10.5 With peripheral circulatory complications
0.765 0.235 0.000
I37 Pulmonary valve disorders
0.765 0.235 0.000
I45.1 Other and unspecified right bundle-branch block
0.765 0.235 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.764 0.236 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.763 0.237 0.000
N00-N08 Glomerular diseases
0.762 0.238 0.000
C79 Secondary malignant neoplasm of other sites
0.762 0.238 0.000
M21 Other acquired deformities of limbs
0.760 0.240 0.000
M81 Osteoporosis without pathological fracture
0.758 0.242 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.758 0.242 0.000
M60-M63 Disorders of muscles
0.758 0.242 0.000
I69 Sequelae of cerebrovascular disease
0.758 0.242 0.000
S54 Injury of nerves at forearm level
0.756 0.244 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.756 0.244 0.000
J39.8 Other specified diseases of upper respiratory tract
0.756 0.244 0.000
I25.4 Coronary artery aneurysm
0.754 0.246 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.754 0.246 0.000
S05 Injury of eye and orbit
0.754 0.246 0.000
D41.0 Kidney
0.754 0.246 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.753 0.246 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.752 0.248 0.000
E50-E64 Other nutritional deficiencies
0.751 0.249 0.000
C56 Malignant neoplasm of ovary
0.751 0.249 0.000
S06.4 Epidural haemorrhage
0.751 0.249 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.751 0.249 0.000
Q80-Q89 Other congenital malformations
0.750 0.250 0.000
H02.2 Lagophthalmos
0.750 0.250 0.000
I77.8 Other specified disorders of arteries and arterioles
0.750 0.250 0.000
S06.2 Diffuse brain injury
0.749 0.251 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.749 0.251 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.748 0.252 0.000
E89.2 Postprocedural hypoparathyroidism
0.748 0.252 0.000
I45.6 Preexcitation syndrome
0.747 0.253 0.000
M71 Other bursopathies
0.747 0.253 0.000
H36 Retinal disorders in diseases classified elsewhere
0.747 0.253 0.000
N18.5 Chronic kidney disease, stage 5
0.747 0.253 0.000
V80-V89 Other land transport accidents
0.747 0.253 0.000
M40-M43 Deforming dorsopathies
0.746 0.254 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.745 0.255 0.000
H10-H13 Disorders of conjunctiva
0.744 0.256 0.000
V40-V49 Car occupant injured in transport accident
0.744 0.256 0.000
H04.8 Other disorders of lachrymal system
0.744 0.256 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.744 0.256 0.000
M79.1 Myalgia
0.743 0.257 0.000
I24 Other acute ischaemic heart diseases
0.743 0.257 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.742 0.258 0.000
S52 Fracture of forearm
0.741 0.259 0.000
M24 Other specific joint derangements
0.740 0.260 0.000
T79-T79 Certain early complications of trauma
0.739 0.260 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.739 0.261 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.738 0.262 0.000
S06.5 Traumatic subdural haemorrhage
0.737 0.263 0.000
Y00-Y09 Assault
0.736 0.264 0.000
S40-S49 Injuries to the shoulder and upper arm
0.735 0.264 0.000
S01.3 Open wound of ear
0.733 0.267 0.000
Q63 Other congenital malformations of kidney
0.732 0.268 0.000
S56 Injury of muscle and tendon at forearm level
0.732 0.268 0.000
N10 Acute tubulo-interstitial nephritis
0.732 0.268 0.000
S91.3 Open wound of other parts of foot
0.731 0.269 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.728 0.271 0.000
S09.9 Unspecified injury of head
0.728 0.272 0.000
Q24 Other congenital malformations of heart
0.728 0.272 0.000
C53 Malignant neoplasm of cervix uteri
0.727 0.272 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.727 0.273 0.000
E34 Other endocrine disorders
0.727 0.273 0.000
M51.8 Other specified intervertebral disk disorders
0.727 0.273 0.000
S80-S89 Injuries to the knee and lower leg
0.727 0.273 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.726 0.274 0.000
I61.8 Other intracerebral haemorrhage
0.725 0.275 0.000
H02.5 Other disorders affecting eyelid function
0.725 0.275 0.000
M76.6 Achilles tendinitis
0.725 0.275 0.000
E20 Hypoparathyroidism
0.724 0.276 0.000
H31 Other disorders of choroid
0.723 0.277 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.722 0.278 0.000
J38.0 Paralysis of vocal cords and larynx
0.720 0.279 0.000
S51.9 Open wound of forearm, part unspecified
0.720 0.280 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.718 0.282 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.718 0.282 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S01.8 Open wound of other parts of head
0.715 0.285 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.715 0.285 0.000
H04.9 Disorder of lachrymal system, unspecified
0.714 0.286 0.000
D46 Myelodysplastic syndromes
0.713 0.286 0.000
I23 Certain current complications following acute myocardial infarction
0.713 0.287 0.000
H53.1 Subjective visual disturbances
0.713 0.287 0.000
I78.1 Naevus, nonneoplastic
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
I30 Acute pericarditis
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.710 0.290 0.000
N18.9 Chronic renal failure, unspecified
0.709 0.291 0.000
Y60.8 During other surgical and medical care
0.709 0.291 0.000
D44.0 Thyroid gland
0.709 0.291 0.000
E24 Cushing's syndrome
0.708 0.291 0.000
Q00-Q07 Congenital malformations of the nervous system
0.708 0.291 0.000
E11.1 With ketoacidosis
0.708 0.291 0.000
V10-V19 Pedal cyclist injured in transport accident
0.708 0.292 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.707 0.293 0.000
I63.8 Other cerebral infarction
0.707 0.293 0.000
C64-C68 Malignant neoplasms of urinary tract
0.706 0.293 0.000
S08 Traumatic amputation of part of head
0.706 0.294 0.000
S07 Crushing injury of head
0.706 0.294 0.000
S04 Injury of cranial nerves
0.706 0.294 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.706 0.294 0.000
M91-M94 Chondropathies
0.706 0.294 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.706 0.294 0.000
G70-G73 Diseases of myoneural junction and muscle
0.706 0.294 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.706 0.294 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.705 0.295 0.000
Q50-Q56 Congenital malformations of genital organs
0.705 0.295 0.000
I25.6 Silent myocardial ischaemia
0.705 0.295 0.000
I50 Heart failure
0.704 0.296 0.000
E13 Other specified diabetes mellitus
0.704 0.296 0.000
J38.2 Nodules of vocal cords
0.703 0.297 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.297 0.000
S27 Injury of other and unspecified intrathoracic organs
0.702 0.297 0.000
N18.0 End-stage renal disease
0.702 0.298 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.702 0.298 0.000
E10.9 Without complications
0.702 0.298 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.700 0.299 0.000
Q35-Q37 Cleft lip and cleft palate
0.700 0.299 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.700 0.299 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.700 0.299 0.000
S99 Other and unspecified injuries of ankle and foot
0.700 0.300 0.000
G95 Other diseases of spinal cord
0.700 0.300 0.000
I52 Other heart disorders in diseases classified elsewhere
0.700 0.300 0.000
I48 Atrial fibrillation and flutter
0.700 0.300 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.700 0.300 0.000
I41 Myocarditis in diseases classified elsewhere
0.700 0.300 0.000
I40 Acute myocarditis
0.700 0.300 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.700 0.300 0.000
I32 Pericarditis in diseases classified elsewhere
0.700 0.300 0.000
J37 Chronic laryngitis and laryngotracheitis
0.699 0.301 0.000
S00.0 Superficial injury of scalp
0.699 0.301 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.699 0.301 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.698 0.302 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.697 0.303 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.697 0.303 0.000
S22.3 Fracture of rib
0.697 0.303 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.696 0.303 0.000
H55 Nystagmus and other irregular eye movements
0.696 0.304 0.000
M85 Other disorders of bone density and structure
0.696 0.304 0.000
I33 Acute and subacute endocarditis
0.696 0.304 0.000
H02.4 Ptosis of eyelid
0.696 0.304 0.000
E11.5 With peripheral circulatory complications
0.695 0.305 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.305 0.000
Y10-Y34 Event of undetermined intent
0.694 0.305 0.000
X85-X99 Assault
0.694 0.305 0.000
X30-X39 Exposure to forces of nature
0.694 0.305 0.000
X10-X19 Contact with heat and hot substances
0.694 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.305 0.000
W75-W84 Other accidental threats to breathing
0.694 0.305 0.000
W65-W74 Accidental drowning and submersion
0.694 0.305 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.305 0.000
V95-V97 Air and space transport accidents
0.694 0.305 0.000
V90-V94 Water transport accidents
0.694 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.305 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.305 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.694 0.306 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.693 0.307 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.692 0.308 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.691 0.309 0.000
E29.1 Testicular hypofunction
0.691 0.309 0.000
G91 Hydrocephalus
0.691 0.309 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.690 0.310 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.690 0.310 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.689 0.311 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.688 0.312 0.000
J03 Acute tonsillitis
0.688 0.312 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.687 0.313 0.000
N11 Chronic tubulo-interstitial nephritis
0.687 0.313 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.687 0.313 0.000
I21.9 Acute myocardial infarction, unspecified
0.687 0.313 0.000
X60-X84 Intentional self-harm
0.687 0.313 0.000
S00.1 Contusion of eyelid and periocular area
0.686 0.314 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.685 0.315 0.000
E11.2 With renal complications
0.685 0.315 0.000
M89 Other disorders of bone
0.684 0.316 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.684 0.316 0.000
H36.0 Diabetic retinopathy
0.684 0.316 0.000
X20-X29 Contact with venomous animals and plants
0.684 0.316 0.000
N18.3 Chronic kidney disease, stage 3
0.683 0.317 0.000
J30 Vasomotor and allergic rhinitis
0.682 0.318 0.000
S90.3 Contusion of other and unspecified parts of foot
0.682 0.318 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.682 0.318 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.682 0.318 0.000
M51.3 Other specified intervertebral disk degeneration
0.682 0.318 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.682 0.318 0.000
M51.4 Schmorl's nodes
0.682 0.318 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.682 0.318 0.000
G93 Other disorders of brain
0.681 0.319 0.000
W13 Fall from, out of or through building or structure
0.681 0.319 0.000
S81 Open wound of lower leg
0.680 0.320 0.000
S19 Other and unspecified injuries of neck
0.680 0.320 0.000
M82 Osteoporosis in diseases classified elsewhere
0.680 0.320 0.000
Y88 Sequelae of surgical and medical care as external cause
0.680 0.320 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.679 0.321 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.679 0.321 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.678 0.322 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.678 0.322 0.000
S29 Other and unspecified injuries of thorax
0.678 0.322 0.000
M21.2 Flexion deformity
0.678 0.322 0.000
I42.6 Alcoholic cardiomyopathy
0.678 0.322 0.000
E12 Malnutrition-related diabetes mellitus
0.677 0.323 0.000
T86.1 Kidney transplant failure and rejection
0.677 0.323 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.675 0.325 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.675 0.325 0.000
J35 Chronic diseases of tonsils and adenoids
0.675 0.325 0.000
E85 Amyloidosis
0.675 0.325 0.000
E84 Cystic fibrosis
0.675 0.325 0.000
E79 Disorders of purine and pyrimidine metabolism
0.675 0.325 0.000
E77 Disorders of glycoprotein metabolism
0.675 0.325 0.000
E76 Disorders of glycosaminoglycan metabolism
0.675 0.325 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.675 0.325 0.000
E74 Other disorders of carbohydrate metabolism
0.675 0.325 0.000
E73 Lactose intolerance
0.675 0.325 0.000
E72 Other disorders of amino-acid metabolism
0.675 0.325 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.675 0.325 0.000
E70 Disorders of aromatic amino-acid metabolism
0.675 0.325 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.675 0.325 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.675 0.325 0.000
N18.4 Chronic kidney disease, stage 4
0.674 0.326 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.674 0.326 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.674 0.326 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.674 0.326 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.674 0.326 0.000
J81 Pulmonary oedema
0.674 0.326 0.000
D00-D09 In situ neoplasms
0.674 0.326 0.000
Q23 Congenital malformations of aortic and mitral valves
0.674 0.326 0.000
S06.9 Intracranial injury, unspecified
0.672 0.328 0.000
S06.8 Other intracranial injuries
0.672 0.328 0.000
S06.7 Intracranial injury with prolonged coma
0.672 0.328 0.000
S06.1 Traumatic cerebral oedema
0.672 0.328 0.000
I70 Atherosclerosis
0.672 0.328 0.000
M79.7 Fibromyalgia
0.670 0.330 0.000
S98 Traumatic amputation of ankle and foot
0.670 0.330 0.000
S97 Crushing injury of ankle and foot
0.670 0.330 0.000
S95 Injury of blood vessels at ankle and foot level
0.670 0.330 0.000
S94 Injury of nerves at ankle and foot level
0.670 0.330 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.670 0.330 0.000
E89.3 Postprocedural hypopituitarism
0.670 0.330 0.000
H57 Other disorders of eye and adnexa
0.670 0.330 0.000
I74.5 Embolism and thrombosis of iliac artery
0.669 0.331 0.000
E61 Deficiency of other nutrient elements
0.669 0.331 0.000
H01.0 Blepharitis
0.668 0.332 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.668 0.332 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.668 0.332 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.668 0.332 0.000
E89.5 Postprocedural testicular hypofunction
0.668 0.332 0.000
E89.4 Postprocedural ovarian failure
0.668 0.332 0.000
E89.1 Postprocedural hypoinsulinaemia
0.668 0.332 0.000
D48.7 Other specified sites
0.668 0.332 0.000
S06.0 Concussion
0.668 0.332 0.000
T87 Complications peculiar to reattachment and amputation
0.668 0.332 0.000
S00.3 Superficial injury of nose
0.668 0.332 0.000
S59 Other and unspecified injuries of forearm
0.667 0.333 0.000
S58 Traumatic amputation of forearm
0.667 0.333 0.000
S57 Crushing injury of forearm
0.667 0.333 0.000
S55 Injury of blood vessels at forearm level
0.667 0.333 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.667 0.333 0.000
E22 Hyperfunction of pituitary gland
0.667 0.333 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.665 0.335 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.664 0.336 0.000
E32 Diseases of thymus
0.664 0.336 0.000
E31 Polyglandular dysfunction
0.664 0.336 0.000
E30 Disorders of puberty, not elsewhere classified
0.664 0.336 0.000
E26 Hyperaldosteronism
0.664 0.336 0.000
E25 Adrenogenital disorders
0.664 0.336 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.664 0.336 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.663 0.337 0.000
Y43 Primarily systemic agents
0.662 0.338 0.000
N13.4 Hydroureter
0.662 0.338 0.000
H02.0 Entropion and trichiasis of eyelid
0.662 0.338 0.000
H54.7 Unspecified visual loss
0.661 0.339 0.000
M83 Adult osteomalacia
0.661 0.339 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.660 0.340 0.000
H35 Other retinal disorders
0.659 0.341 0.000
E23.7 Disorder of pituitary gland, unspecified
0.658 0.342 0.000
C45 Mesothelioma
0.658 0.342 0.000
E88 Other metabolic disorders
0.657 0.342 0.000
S22.30 Fracture of rib (closed)
0.657 0.343 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.656 0.344 0.000
I74.8 Embolism and thrombosis of other arteries
0.656 0.344 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.656 0.344 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.656 0.344 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.656 0.344 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.656 0.344 0.000
J38.6 Stenosis of larynx
0.656 0.344 0.000
J38.5 Laryngeal spasm
0.656 0.344 0.000
G56 Mononeuropathies of upper limb
0.656 0.344 0.000
D41.9 Urinary organ, unspecified
0.655 0.345 0.000
D41.7 Other urinary organs
0.655 0.345 0.000
D41.3 Urethra
0.655 0.345 0.000
D41.2 Ureter
0.655 0.345 0.000
D41.1 Renal pelvis
0.655 0.345 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.655 0.345 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.655 0.345 0.000
G40-G47 Episodic and paroxysmal disorders
0.653 0.347 0.000
Y85 Sequelae of transport accidents
0.652 0.348 0.000
I34.1 Mitral (valve) prolapse
0.652 0.348 0.000
I72.3 Aneurysm of iliac artery
0.652 0.348 0.000
G83 Other paralytic syndromes
0.651 0.349 0.000
M21.0 Valgus deformity, not elsewhere classified
0.651 0.349 0.000
E23.0 Hypopituitarism
0.650 0.350 0.000
S01.9 Open wound of head, part unspecified
0.649 0.351 0.000
M72.9 Fibroblastic disorder, unspecified
0.648 0.351 0.000
M72.8 Other fibroblastic disorders
0.648 0.351 0.000
M72.6 Necrotizing fasciitis
0.648 0.351 0.000
M72.5 Fasciitis, not elsewhere classified
0.648 0.351 0.000
M72.4 Pseudosarcomatous fibromatosis
0.648 0.351 0.000
M72.3 Nodular fasciitis
0.648 0.351 0.000
M72.1 Knuckle pads
0.648 0.351 0.000
D48.1 Connective and other soft tissue
0.648 0.352 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.648 0.352 0.000
H02.6 Xanthelasma of eyelid
0.648 0.352 0.000
I20 Angina pectoris
0.648 0.352 0.000
Q61 Cystic kidney disease
0.647 0.353 0.000
I36 Nonrheumatic tricuspid valve disorders
0.646 0.353 0.000
M79.2 Neuralgia and neuritis, unspecified
0.646 0.354 0.000
I08 Multiple valve diseases
0.645 0.355 0.000
H04.1 Other disorders of lachrymal gland
0.645 0.355 0.000
C54 Malignant neoplasm of corpus uteri
0.644 0.356 0.000
W20-W49 Exposure to inanimate mechanical forces
0.644 0.356 0.000
Y65 Other misadventures during surgical and medical care
0.643 0.356 0.000
Y64 Contaminated medical or biological substances
0.643 0.356 0.000
Y63 Failure in dosage during surgical and medical care
0.643 0.356 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.643 0.356 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.643 0.356 0.000
Y69 Unspecified misadventure during surgical and medical care
0.643 0.356 0.000
Y66 Nonadministration of surgical and medical care
0.643 0.356 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.643 0.357 0.000
I45.8 Other specified conduction disorders
0.643 0.357 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.643 0.357 0.000
I42.8 Other cardiomyopathies
0.643 0.357 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.643 0.357 0.000
I42.5 Other restrictive cardiomyopathy
0.643 0.357 0.000
I42.4 Endocardial fibroelastosis
0.643 0.357 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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