TreeWAS – Variant ID: rs11761528

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.517	0.483
J44 Other chronic obstructive pulmonary disease	0.000	0.563	0.437
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.571	0.429
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.680	0.320
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.743	0.257
J40-J47 Chronic lower respiratory diseases	0.000	0.873	0.127
J42 Unspecified chronic bronchitis	0.000	0.887	0.113
J43 Emphysema	0.000	0.891	0.108
J43.9 Emphysema, unspecified	0.000	0.899	0.101
J46 Status asthmaticus	0.000	0.907	0.093
J41 Simple and mucopurulent chronic bronchitis	0.000	0.908	0.091
J43.8 Other emphysema	0.000	0.922	0.078
J43.1 Panlobular emphysema	0.000	0.922	0.078
J43.0 MacLeod's syndrome	0.000	0.922	0.078
J45 Asthma	0.000	0.933	0.067
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.934	0.066
J41.1 Mucopurulent chronic bronchitis	0.000	0.934	0.066
J41.0 Simple chronic bronchitis	0.000	0.934	0.066
J40 Bronchitis, not specified as acute or chronic	0.000	0.939	0.061
J45.0 Predominantly allergic asthma	0.000	0.945	0.055
J43.2 Centrilobular emphysema	0.000	0.946	0.054
J45.8 Mixed asthma	0.000	0.951	0.048
J45.1 Nonallergic asthma	0.000	0.951	0.048
J47 Bronchiectasis	0.000	0.970	0.030
O46.9 Antepartum haemorrhage, unspecified	0.025	0.975	0.000
D69.6 Thrombocytopenia, unspecified	0.021	0.979	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.020	0.979	0.000
I10 Essential (primary) hypertension	0.000	0.980	0.020
D69 Purpura and other haemorrhagic conditions	0.019	0.981	0.000
O36.8 Maternal care for other specified foetal problems	0.018	0.982	0.000
O36 Maternal care for other known or suspected foetal problems	0.018	0.982	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.017	0.983	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.016	0.984	0.000
D68 Other coagulation defects	0.016	0.984	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.016	0.984	0.000
O48 Prolonged pregnancy	0.016	0.984	0.000
O46.8 Other antepartum haemorrhage	0.015	0.985	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.015	0.985	0.000
D69.5 Secondary thrombocytopenia	0.015	0.985	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.985	0.015
O34 Maternal care for known or suspected abnormality of pelvic organs	0.015	0.985	0.000
O44 Placenta praevia	0.014	0.986	0.000
D68.5 Primary Thrombophilia	0.014	0.986	0.000
D68.8 Other specified coagulation defects	0.014	0.986	0.000
O30 Multiple gestation	0.014	0.986	0.000
D68.2 Hereditary deficiency of other clotting factors	0.014	0.986	0.000
O42 Premature rupture of membranes	0.014	0.986	0.000
D69.8 Other specified haemorrhagic conditions	0.014	0.986	0.000
D69.2 Other nonthrombocytopenic purpura	0.014	0.986	0.000
D69.1 Qualitative platelet defects	0.014	0.986	0.000
D69.4 Other primary thrombocytopenia	0.013	0.986	0.000
D69.9 Haemorrhagic condition, unspecified	0.013	0.986	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.013	0.987	0.000
O36.6 Maternal care for excessive foetal growth	0.013	0.987	0.000
O33 Maternal care for known or suspected disproportion	0.013	0.987	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.013	0.987	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.013	0.987	0.000
O36.9 Maternal care for foetal problem, unspecified	0.013	0.987	0.000
O45 Premature separation of placenta [abruptio placentae]	0.013	0.987	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.013	0.987	0.000
O36.2 Maternal care for hydrops foetalis	0.013	0.987	0.000
O36.1 Maternal care for other isoimmunisation	0.013	0.987	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.013	0.987	0.000
O31 Complications specific to multiple gestation	0.013	0.987	0.000
D68.6 Other Thrombophilia	0.013	0.987	0.000
D69.0 Allergic purpura	0.012	0.987	0.000
O36.4 Maternal care for intra-uterine death	0.012	0.987	0.000
D63.0 Anaemia in neoplastic disease	0.012	0.988	0.000
D67 Hereditary factor IX deficiency	0.012	0.988	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.012	0.988	0.000
D68.4 Acquired coagulation factor deficiency	0.012	0.988	0.000
D68.1 Hereditary factor XI deficiency	0.012	0.988	0.000
O30.0 Twin pregnancy	0.012	0.988	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.012	0.988	0.000
O42.9 Premature rupture of membranes, unspecified	0.012	0.988	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.012	0.988	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.011	0.989	0.000
O34.1 Maternal care for tumour of corpus uteri	0.011	0.989	0.000
O44.1 Placenta praevia with haemorrhage	0.011	0.989	0.000
D68.0 Von Willebrand's disease	0.011	0.989	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.011	0.989	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.011	0.989	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.011	0.989	0.000
O34.6 Maternal care for abnormality of vagina	0.011	0.989	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.011	0.989	0.000
O34.3 Maternal care for cervical incompetence	0.011	0.989	0.000
O34.0 Maternal care for congenital malformation of uterus	0.011	0.989	0.000
D66 Hereditary factor VIII deficiency	0.011	0.989	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.011	0.989	0.000
O41 Other disorders of amniotic fluid and membranes	0.011	0.989	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.011	0.989	0.000
O33.9 Maternal care for disproportion, unspecified	0.010	0.989	0.000
O30.9 Multiple gestation, unspecified	0.010	0.990	0.000
O30.8 Other multiple gestation	0.010	0.990	0.000
O30.2 Quadruplet pregnancy	0.010	0.990	0.000
O30.1 Triplet pregnancy	0.010	0.990	0.000
O34.4 Maternal care for other abnormalities of cervix	0.010	0.990	0.000
O36.5 Maternal care for poor foetal growth	0.010	0.990	0.000
O40 Polyhydramnios	0.010	0.990	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.010	0.990	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.010	0.990	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.010	0.990	0.000
O45.9 Premature separation of placenta, unspecified	0.010	0.990	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.010	0.990	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.010	0.990	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.010	0.990	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.010	0.990	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.010	0.990	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.010	0.990	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.010	0.990	0.000
O33.8 Maternal care for disproportion of other origin	0.010	0.990	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.010	0.990	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.010	0.990	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.010	0.990	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.010	0.990	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.010	0.990	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.010	0.990	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.010	0.990	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.010	0.990	0.000
O43 Placental disorders	0.010	0.990	0.000
N80.3 Endometriosis of pelvic peritoneum	0.000	0.990	0.010
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.010	0.990	0.000
O45.8 Other premature separation of placenta	0.009	0.990	0.000
O45.0 Premature separation of placenta with coagulation defect	0.009	0.990	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.010	0.990	0.000
O31.8 Other complications specific to multiple gestation	0.009	0.991	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.009	0.991	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.009	0.991	0.000
O31.0 Papyraceous foetus	0.009	0.991	0.000
D55-D59 Haemolytic anaemias	0.009	0.991	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.009	0.991	0.000
R13 Dysphagia	0.000	0.991	0.009
D60-D64 Aplastic and other anaemias	0.009	0.991	0.000
O32.4 Maternal care for high head at term	0.009	0.991	0.000
O32.0 Maternal care for unstable lie	0.009	0.991	0.000
O32.8 Maternal care for other malpresentation of foetus	0.008	0.991	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.008	0.991	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.008	0.992	0.000
D68.9 Coagulation defect, unspecified	0.008	0.992	0.000
D75.2 Essential thrombocytosis	0.008	0.992	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.008	0.992	0.000
D75 Other diseases of blood and blood-forming organs	0.008	0.992	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.992	0.008
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.008	0.992	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.000	0.992	0.008
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.008	0.992	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.992	0.008
O32.9 Maternal care for malpresentation of foetus, unspecified	0.008	0.992	0.000
O32.6 Maternal care for compound presentation	0.008	0.992	0.000
O32.3 Maternal care for face, brow and chin presentation	0.008	0.992	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.008	0.992	0.000
O41.1 Infection of amniotic sac and membranes	0.008	0.992	0.000
D58 Other hereditary haemolytic anaemias	0.008	0.992	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.008	0.992	0.000
D72.8 Other specified disorders of white blood cells	0.008	0.992	0.000
O41.0 Oligohydramnios	0.008	0.992	0.000
D56 Thalassaemia	0.008	0.992	0.000
D72 Other disorders of white blood cells	0.008	0.992	0.000
O43.9 Placental disorder, unspecified	0.007	0.993	0.000
O43.2 Morbidly adherent placenta	0.007	0.993	0.000
O43.0 Placental transfusion syndromes	0.007	0.993	0.000
D59 Acquired haemolytic anaemia	0.007	0.993	0.000
I10-I15 Hypertensive diseases	0.000	0.993	0.007
D57 Sickle-cell disorders	0.007	0.993	0.000
D55 Anaemia due to enzyme disorders	0.007	0.993	0.000
D61 Other aplastic anaemias	0.007	0.993	0.000
D56.3 Thalassaemia trait	0.007	0.993	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.007	0.993	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.007	0.993	0.000
N95.0 Postmenopausal bleeding	0.000	0.993	0.007
O43.8 Other placental disorders	0.006	0.993	0.000
D58.0 Hereditary spherocytosis	0.006	0.994	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.006	0.994	0.000
D74 Methaemoglobinaemia	0.006	0.994	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.006	0.994	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.006	0.994	0.000
D75.0 Familial erythrocytosis	0.006	0.994	0.000
D80-D89 Certain disorders involving the immune mechanism	0.006	0.994	0.000
O32.2 Maternal care for transverse and oblique lie	0.006	0.994	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.006	0.994	0.000
D58.2 Other haemoglobinopathies	0.006	0.994	0.000
D58.1 Hereditary elliptocytosis	0.006	0.994	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.006	0.994	0.000
D56.9 Thalassaemia, unspecified	0.006	0.994	0.000
D56.8 Other thalassaemias	0.006	0.994	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.006	0.994	0.000
D56.2 Delta-beta thalassaemia	0.006	0.994	0.000
D56.1 Beta thalassaemia	0.006	0.994	0.000
D56.0 Alpha thalassaemia	0.006	0.994	0.000
D72.9 Disorder of white blood cells, unspecified	0.006	0.994	0.000
D72.0 Genetic anomalies of leukocytes	0.006	0.994	0.000
O47 False labour	0.006	0.994	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.006	0.994	0.000
D59.1 Other autoimmune haemolytic anaemias	0.006	0.994	0.000
D61.1 Drug-induced aplastic anaemia	0.005	0.994	0.000
D59.8 Other acquired haemolytic anaemias	0.005	0.994	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.005	0.994	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.005	0.994	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.005	0.994	0.000
D59.3 Haemolytic-uraemic syndrome	0.005	0.994	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.005	0.994	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.005	0.994	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.995	0.005
O43.1 Malformation of placenta	0.005	0.995	0.000
I13 Hypertensive heart and renal disease	0.000	0.995	0.005
D55.9 Anaemia due to enzyme disorder, unspecified	0.005	0.995	0.000
D55.8 Other anaemias due to enzyme disorders	0.005	0.995	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.005	0.995	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.005	0.995	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.005	0.995	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.005	0.995	0.000
D57.8 Other sickle-cell disorders	0.005	0.995	0.000
D57.3 Sickle-cell trait	0.005	0.995	0.000
D57.2 Double heterozygous sickling disorders	0.005	0.995	0.000
D57.1 Sickle-cell anaemia without crisis	0.005	0.995	0.000
D57.0 Sickle-cell anaemia with crisis	0.005	0.995	0.000
D61.8 Other specified aplastic anaemias	0.005	0.995	0.000
D61.3 Idiopathic aplastic anaemia	0.005	0.995	0.000
D61.2 Aplastic anaemia due to other external agents	0.005	0.995	0.000
D61.0 Constitutional aplastic anaemia	0.005	0.995	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.005	0.995	0.000
D60.8 Other acquired pure red cell aplasias	0.005	0.995	0.000
D60.1 Transient acquired pure red cell aplasia	0.005	0.995	0.000
D60.0 Chronic acquired pure red cell aplasia	0.005	0.995	0.000
I15 Secondary hypertension	0.000	0.995	0.005
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
I11 Hypertensive heart disease	0.000	0.995	0.005
K29.5 Chronic gastritis, unspecified	0.000	0.995	0.005
D61.9 Aplastic anaemia, unspecified	0.005	0.995	0.000
K14.8 Other diseases of tongue	0.005	0.995	0.000
I12 Hypertensive renal disease	0.000	0.995	0.005
D72.1 Eosinophilia	0.005	0.995	0.000
D74.9 Methaemoglobinaemia, unspecified	0.005	0.995	0.000
D74.8 Other methaemoglobinaemias	0.005	0.995	0.000
D74.0 Congenital methaemoglobinaemia	0.005	0.995	0.000
D76.3 Other histiocytosis syndromes	0.005	0.995	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.005	0.995	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.005	0.995	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.005	0.995	0.000
D83 Common variable immunodeficiency	0.005	0.995	0.000
D82 Immunodeficiency associated with other major defects	0.005	0.995	0.000
D81 Combined immunodeficiencies	0.005	0.995	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.005	0.995	0.000
D73 Diseases of spleen	0.005	0.995	0.000
D84 Other immunodeficiencies	0.004	0.995	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.004	0.996	0.000
D50-D53 Nutritional anaemias	0.004	0.996	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.004	0.996	0.000
D80 Immunodeficiency with predominantly antibody defects	0.004	0.996	0.000
D64 Other anaemias	0.004	0.996	0.000
D75.1 Secondary polycythaemia	0.004	0.996	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.004	0.996	0.000
S64 Injury of nerves at wrist and hand level	0.004	0.996	0.000
K74.3 Primary biliary cirrhosis	0.004	0.996	0.000
I21 Acute myocardial infarction	0.000	0.996	0.004
D75.8 Other specified diseases of blood and blood-forming organs	0.004	0.996	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.996	0.004
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.996	0.004
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.996	0.004
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.996	0.004
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.996	0.004
I15.1 Hypertension secondary to other renal disorders	0.000	0.996	0.004
I12.9 Hypertensive renal disease without renal failure	0.000	0.996	0.004
O47.9 False labour, unspecified	0.004	0.996	0.000
I15.8 Other secondary hypertension	0.000	0.996	0.004
I15.2 Hypertension secondary to endocrine disorders	0.000	0.996	0.004
I15.0 Renovascular hypertension	0.000	0.996	0.004
D25 Leiomyoma of uterus	0.000	0.996	0.004
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.996	0.004
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.996	0.004
O86.0 Infection of obstetric surgical wound	0.004	0.996	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.996	0.004
D62 Acute posthaemorrhagic anaemia	0.003	0.996	0.000
O86 Other puerperal infections	0.004	0.996	0.000
D51 Vitamin B12 deficiency anaemia	0.004	0.996	0.000
S64.3 Injury of digital nerve of thumb	0.004	0.996	0.000
I15.9 Seconday hypertension, unspecified	0.000	0.996	0.003
D81.9 Combined immunodeficiency, unspecified	0.003	0.996	0.000
D81.8 Other combined immunodeficiencies	0.003	0.996	0.000
D81.7 Major histocompatibility complex class II deficiency	0.003	0.996	0.000
D81.6 Major histocompatibility complex class I deficiency	0.003	0.996	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.003	0.996	0.000
D81.4 Nezelof's syndrome	0.003	0.996	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.003	0.996	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.003	0.996	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.003	0.996	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.003	0.996	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.003	0.996	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.003	0.996	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.003	0.996	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.003	0.996	0.000
D82.2 Immunodeficiency with short-limbed stature	0.003	0.996	0.000
D82.1 Di George's syndrome	0.003	0.996	0.000
D82.0 Wiskott-Aldrich syndrome	0.003	0.996	0.000
D83.9 Common variable immunodeficiency, unspecified	0.003	0.996	0.000
D83.8 Other common variable immunodeficiencies	0.003	0.996	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.003	0.996	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.003	0.996	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.003	0.996	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.004	0.996	0.000
D73.9 Disease of spleen, unspecified	0.003	0.996	0.000
D73.8 Other diseases of spleen	0.003	0.996	0.000
D73.4 Cyst of spleen	0.003	0.996	0.000
D73.3 Abscess of spleen	0.003	0.996	0.000
D73.2 Chronic congestive splenomegaly	0.003	0.996	0.000
D73.1 Hypersplenism	0.003	0.996	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.004	0.996	0.000
D84.8 Other specified immunodeficiencies	0.003	0.996	0.000
D84.1 Defects in the complement system	0.003	0.996	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.003	0.996	0.000
S64.4 Injury of digital nerve of other finger	0.004	0.996	0.000
S60-S69 Injuries to the wrist and hand	0.004	0.996	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.003	0.996	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.003	0.996	0.000
D64.8 Other specified anaemias	0.003	0.996	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.997	0.003
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.003	0.997	0.000
D53 Other nutritional anaemias	0.003	0.997	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.003	0.997	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.003	0.997	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.003	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.003	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.003	0.997	0.000
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
D64.4 Congenital dyserythropoietic anaemia	0.003	0.997	0.000
D64.3 Other sideroblastic anaemias	0.003	0.997	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.003	0.997	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.003	0.997	0.000
D64.0 Hereditary sideroblastic anaemia	0.003	0.997	0.000
Z37.0 Single live birth	0.003	0.997	0.000
O85-O92 Complications predominantly related to the puerperium	0.003	0.997	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.003	0.997	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.003	0.997	0.000
S64.8 Injury of other nerves at wrist and hand level	0.003	0.997	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.003	0.997	0.000
S64.1 Injury of median nerve at wrist and hand level	0.003	0.997	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.997	0.003
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
D73.5 Infarction of spleen	0.003	0.997	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.997	0.003
O86.4 Pyrexia of unknown origin following delivery	0.003	0.997	0.000
D25.1 Intramural leiomyoma of uterus	0.000	0.997	0.003
T39.1 4-Aminophenol derivatives	0.000	0.997	0.003
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.003	0.997	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.003	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
D86 Sarcoidosis	0.003	0.997	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.003	0.997	0.000
S60 Superficial injury of wrist and hand	0.003	0.997	0.000
O86.1 Other infection of genital tract following delivery	0.003	0.997	0.000
S63.6 Sprain and strain of finger(s)	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
S62.51 Fracture of thumb (open)	0.003	0.997	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.003	0.997	0.000
J95.0 Tracheostomy malfunction	0.000	0.997	0.003
O86.8 Other specified puerperal infections	0.003	0.997	0.000
O86.3 Other genito-urinary tract infections following delivery	0.003	0.997	0.000
O86.2 Urinary tract infection following delivery	0.003	0.997	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.003	0.997	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.003	0.997	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.003	0.997	0.000
D51.2 Transcobalamin II deficiency	0.003	0.997	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.003	0.997	0.000
S69 Other and unspecified injuries of wrist and hand	0.003	0.997	0.000
O82.0 Delivery by elective Caesarean section	0.003	0.997	0.000
D52 Folate deficiency anaemia	0.003	0.997	0.000
O82 Single delivery by Caesarean section	0.003	0.997	0.000
S65 Injury of blood vessels at wrist and hand level	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.997	0.003
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.997	0.003
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.997	0.003
O80-O84 Delivery	0.003	0.997	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.003	0.997	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.997	0.003
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.003	0.997	0.000
D53.9 Nutritional anaemia, unspecified	0.003	0.997	0.000
D53.8 Other specified nutritional anaemias	0.003	0.997	0.000
D53.2 Scorbutic anaemia	0.003	0.997	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.003	0.997	0.000
D53.0 Protein deficiency anaemia	0.003	0.997	0.000
O63.1 Prolonged second stage (of labour)	0.003	0.997	0.000
O90 Complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
C32.0 Glottis	0.000	0.997	0.003
O47.0 False labour before 37 completed weeks of gestation	0.002	0.997	0.001
S61.0 Open wound of finger(s) without damage to nail	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
O91 Infections of breast associated with childbirth	0.003	0.997	0.000
O89 Complications of anaesthesia during the puerperium	0.003	0.997	0.000
O88 Obstetric embolism	0.003	0.997	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.997	0.003
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.997	0.003
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.997	0.003
O85 Puerperal sepsis	0.003	0.997	0.000
S62.5 Fracture of thumb	0.003	0.997	0.000
O32.1 Maternal care for breech presentation	0.002	0.997	0.001
S01.9 Open wound of head, part unspecified	0.000	0.997	0.003
S60.0 Contusion of finger(s) without damage to nail	0.003	0.997	0.000
S63.0 Dislocation of wrist	0.002	0.997	0.000
K74 Fibrosis and cirrhosis of liver	0.003	0.997	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.002	0.997	0.000
S63.1 Dislocation finger	0.002	0.997	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.002	0.997	0.000
S63.5 Sprain and strain of wrist	0.002	0.997	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.002	0.997	0.000
S63.2 Multiple dislocations of fingers	0.002	0.997	0.000
D86.3 Sarcoidosis of skin	0.002	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.003	0.997	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.002	0.997	0.000
S60.1 Contusion of finger(s) with damage to nail	0.002	0.997	0.000
O87 Venous complications in the puerperium	0.002	0.997	0.000
K51.9 Ulcerative colitis, unspecified	0.003	0.997	0.000
O66 Other obstructed labour	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.002	0.997	0.000
S60.8 Other superficial injuries of wrist and hand	0.002	0.997	0.000
S60.2 Contusion of other parts of wrist and hand	0.002	0.997	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.002	0.997	0.000
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
S69.9 Unspecified injury of wrist and hand	0.002	0.998	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.998	0.002
T39.0 Salicylates	0.000	0.998	0.002
S65.5 Injury of blood vessel(s) of other finger	0.002	0.998	0.000
I08 Multiple valve diseases	0.000	0.998	0.002
K74.5 Biliary cirrhosis, unspecified	0.002	0.998	0.000
O60-O75 Complications of labour and delivery	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
O92.1 Cracked nipple associated with childbirth	0.002	0.998	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.002	0.998	0.000
S68 Traumatic amputation of wrist and hand	0.002	0.998	0.000
S67 Crushing injury of wrist and hand	0.002	0.998	0.000
J95-J99 Other diseases of the respiratory system	0.000	0.998	0.002
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
D73.0 Hyposplenism	0.002	0.998	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.002	0.998	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.002	0.998	0.000
S69.8 Other specified injuries of wrist and hand	0.002	0.998	0.000
S69.7 Multiple injuries of wrist and hand	0.002	0.998	0.000
O73 Retained placenta and membranes, without haemorrhage	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
D52.8 Other folate deficiency anaemias	0.002	0.998	0.000
D52.1 Drug-induced folate deficiency anaemia	0.002	0.998	0.000
D52.0 Dietary folate deficiency anaemia	0.002	0.998	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.002	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.002	0.998	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.002	0.998	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.002	0.998	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.002	0.998	0.000
S65.4 Injury of blood vessel(s) of thumb	0.002	0.998	0.000
S65.3 Injury of deep palmar arch	0.002	0.998	0.000
S65.2 Injury of superficial palmar arch	0.002	0.998	0.000
S65.1 Injury of radial artery at wrist and hand level	0.002	0.998	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
S62 Fracture at wrist and hand level	0.002	0.998	0.000
C32.9 Larynx, unspecified	0.000	0.998	0.002
J95.5 Postprocedural subglottic stenosis	0.000	0.998	0.002
J95.4 Mendelson's syndrome	0.000	0.998	0.002
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.998	0.002
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.000	0.998	0.002
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.998	0.002
N80.0 Endometriosis of uterus	0.000	0.998	0.002
O64.1 Obstructed labour due to breech presentation	0.002	0.998	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.002	0.998	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.002	0.998	0.000
N80 Endometriosis	0.000	0.998	0.002
O84 Multiple delivery	0.002	0.998	0.000
O83 Other assisted single delivery	0.002	0.998	0.000
O63 Long labour	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.002	0.998	0.000
C32 Malignant neoplasm of larynx	0.000	0.998	0.002
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
O92.7 Other and unspecified disorders of lactation	0.002	0.998	0.000
O92.6 Galactorrhoea	0.002	0.998	0.000
O92.5 Suppressed lactation	0.002	0.998	0.000
O92.4 Hypogalactia	0.002	0.998	0.000
O92.3 Agalactia	0.002	0.998	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.002	0.998	0.000
O92.0 Retracted nipple associated with childbirth	0.002	0.998	0.000
O90.9 Complication of the puerperium, unspecified	0.002	0.998	0.000
O90.5 Postpartum thyroiditis	0.002	0.998	0.000
O90.4 Postpartum acute renal failure	0.002	0.998	0.000
O90.3 Cardiomyopathy in the puerperium	0.002	0.998	0.000
O90.2 Haematoma of obstetric wound	0.002	0.998	0.000
O90.1 Disruption of perineal obstetric wound	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations