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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117626347
log Bayes Factor = 17.0112
Chromosome 14   position 79,813,041  (GRCh37) Explore rs117626347 on Ensembl!
Variant rs117626347 is part of Cluster X0083

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
M70-M79 Other soft tissue disorders
0.998 0.002 0.000
M25 Other joint disorders, not elsewhere classified
0.998 0.002 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
I50 Heart failure
0.995 0.005 0.000
M79.6 Pain in limb
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.989 0.011 0.000
M25.5 Pain in joint
0.987 0.013 0.000
M65-M68 Disorders of synovium and tendon
0.985 0.015 0.000
I42 Cardiomyopathy
0.983 0.017 0.000
Chapter XIV Diseases of the genitourinary system
0.982 0.018 0.000
H40-H42 Glaucoma
0.981 0.019 0.000
I50.9 Heart failure, unspecified
0.978 0.022 0.000
I77 Other disorders of arteries and arterioles
0.978 0.022 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.971 0.029 0.000
I74 Arterial embolism and thrombosis
0.968 0.032 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.968 0.032 0.000
H40 Glaucoma
0.967 0.033 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.959 0.041 0.000
M25.54 Pain in joint (Hand)
0.959 0.041 0.000
Chapter VI Diseases of the nervous system
0.956 0.044 0.000
N17-N19 Renal failure
0.954 0.046 0.000
I50.1 Left ventricular failure
0.954 0.046 0.000
M79.60 Pain in limb (Multiple sites)
0.953 0.047 0.000
N18 Chronic renal failure
0.949 0.051 0.000
I42.9 Cardiomyopathy, unspecified
0.948 0.052 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.948 0.052 0.000
N18.9 Chronic renal failure, unspecified
0.946 0.054 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.944 0.056 0.000
M79.66 Pain in limb (Lower leg)
0.942 0.058 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.940 0.060 0.000
I20-I25 Ischaemic heart diseases
0.940 0.060 0.000
M65 Synovitis and tenosynovitis
0.939 0.061 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.937 0.063 0.000
R47-R49 Symptoms and signs involving speech and voice
0.935 0.065 0.000
I77.1 Stricture of artery
0.935 0.065 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.934 0.066 0.000
M25.50 Pain in joint (Multiple sites)
0.934 0.066 0.000
N25-N29 Other disorders of kidney and ureter
0.932 0.068 0.000
H53-H54 Visual disturbances and blindness
0.924 0.076 0.000
I20 Angina pectoris
0.923 0.077 0.000
I20.9 Angina pectoris, unspecified
0.918 0.082 0.000
R30-R39 Symptoms and signs involving the urinary system
0.917 0.083 0.000
I05-I09 Chronic rheumatic heart diseases
0.913 0.087 0.000
H40.9 Glaucoma, unspecified
0.913 0.087 0.000
H40.2 Primary angle-closure glaucoma
0.912 0.088 0.000
Y83.3 Surgical operation with formation of external stoma
0.905 0.095 0.000
R35 Polyuria
0.905 0.095 0.000
M67 Other disorders of synovium and tendon
0.904 0.096 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.899 0.101 0.000
I74.5 Embolism and thrombosis of iliac artery
0.897 0.103 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.891 0.109 0.000
N30-N39 Other diseases of urinary system
0.891 0.109 0.000
M79.62 Pain in limb (Upper arm)
0.889 0.111 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.889 0.111 0.000
Y52 Agents primarily affecting the cardiovascular system
0.887 0.113 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.885 0.115 0.000
M05-M14 Inflammatory polyarthropathies
0.884 0.116 0.000
H00 Hordeolum and chalazion
0.881 0.119 0.000
R05 Cough
0.879 0.121 0.000
N20-N23 Urolithiasis
0.878 0.122 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.876 0.124 0.000
M21 Other acquired deformities of limbs
0.876 0.124 0.000
Chapter XXII Codes for special purposes
0.871 0.129 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.870 0.130 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.866 0.134 0.000
H00.1 Chalazion
0.866 0.134 0.000
M25.7 Osteophyte
0.865 0.135 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.864 0.136 0.000
M91-M94 Chondropathies
0.863 0.137 0.000
I73 Other peripheral vascular diseases
0.862 0.137 0.000
T79-T79 Certain early complications of trauma
0.862 0.138 0.000
M25.8 Other specified joint disorders
0.860 0.140 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.859 0.141 0.000
H30-H36 Disorders of choroid and retina
0.859 0.141 0.000
I77.6 Arteritis, unspecified
0.859 0.141 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.858 0.141 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.857 0.143 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.857 0.143 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.855 0.145 0.000
H53 Visual disturbances
0.855 0.145 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.852 0.148 0.000
I35 Nonrheumatic aortic valve disorders
0.848 0.152 0.000
M77 Other enthesopathies
0.847 0.153 0.000
R06 Abnormalities of breathing
0.846 0.154 0.000
I42.0 Dilated cardiomyopathy
0.844 0.156 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.843 0.157 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.842 0.158 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.842 0.158 0.000
N28.1 Cyst of kidney, acquired
0.842 0.158 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.842 0.158 0.000
T66-T78 Other and unspecified effects of external causes
0.841 0.159 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.839 0.161 0.000
R20 Disturbances of skin sensation
0.837 0.163 0.000
I08 Multiple valve diseases
0.837 0.163 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.837 0.163 0.000
M25.3 Other instability of joint
0.837 0.163 0.000
M25.4 Effusion of joint
0.836 0.164 0.000
I44 Atrioventricular and left bundle-branch block
0.836 0.164 0.000
R47 Speech disturbances, not elsewhere classified
0.834 0.166 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.831 0.169 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.830 0.170 0.000
M72 Fibroblastic disorders
0.828 0.171 0.000
H40.5 Glaucoma secondary to other eye disorders
0.827 0.173 0.000
M24 Other specific joint derangements
0.826 0.174 0.000
I33 Acute and subacute endocarditis
0.825 0.174 0.000
M79.0 Rheumatism, unspecified
0.825 0.175 0.000
R02 Gangrene, not elsewhere classified
0.824 0.176 0.000
M22 Disorders of patella
0.824 0.176 0.000
M67.8 Other specified disorders of synovium and tendon
0.821 0.179 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.820 0.180 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.819 0.181 0.000
Chapter V Mental and behavioural disorders
0.817 0.183 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.817 0.183 0.000
R49 Voice disturbances
0.816 0.184 0.000
G90-G99 Other disorders of the nervous system
0.810 0.190 0.000
R23 Other skin changes
0.810 0.190 0.000
G12 Spinal muscular atrophy and related syndromes
0.808 0.192 0.000
I24 Other acute ischaemic heart diseases
0.808 0.192 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.808 0.192 0.000
M25.56 Pain in joint (Lower leg)
0.808 0.192 0.000
S90-S99 Injuries to the ankle and foot
0.807 0.193 0.000
I77.8 Other specified disorders of arteries and arterioles
0.806 0.194 0.000
M25.53 Pain in joint (Forearm)
0.804 0.196 0.000
M79.1 Myalgia
0.803 0.197 0.000
T93 Sequelae of injuries of lower limb
0.803 0.197 0.000
N99-N99 Other disorders of the genitourinary system
0.802 0.198 0.000
N30 Cystitis
0.799 0.201 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.797 0.203 0.000
I42.8 Other cardiomyopathies
0.794 0.206 0.000
I73.9 Peripheral vascular disease, unspecified
0.792 0.208 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.789 0.211 0.000
I78 Diseases of capillaries
0.788 0.212 0.000
Y57 Other and unspecified drugs and medicaments
0.784 0.216 0.000
T82.3 Mechanical complication of other vascular grafts
0.782 0.218 0.000
M05 Seropositive rheumatoid arthritis
0.780 0.220 0.000
H20 Iridocyclitis
0.779 0.221 0.000
M25.78 Osteophyte (Other)
0.778 0.222 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.778 0.222 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.778 0.222 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.778 0.222 0.000
T91 Sequelae of injuries of neck and trunk
0.778 0.222 0.000
G62 Other polyneuropathies
0.771 0.229 0.000
M79.8 Other specified soft tissue disorders
0.770 0.230 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.769 0.230 0.000
M35 Other systemic involvement of connective tissue
0.769 0.231 0.000
M25.57 Pain in joint (Ankle and foot)
0.767 0.233 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.766 0.234 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.766 0.234 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.766 0.234 0.000
M23 Internal derangement of knee
0.765 0.235 0.000
G12.2 Motor neuron disease
0.765 0.235 0.000
M66 Spontaneous rupture of synovium and tendon
0.764 0.235 0.000
V40-V49 Car occupant injured in transport accident
0.762 0.238 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.761 0.239 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.760 0.240 0.000
M00-M03 Infectious arthropathies
0.759 0.241 0.000
N20 Calculus of kidney and ureter
0.758 0.242 0.000
H53.8 Other visual disturbances
0.758 0.242 0.000
I44.7 Left bundle-branch block, unspecified
0.757 0.243 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.756 0.244 0.000
I35.1 Aortic (valve) insufficiency
0.756 0.244 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.756 0.244 0.000
Y84.2 Radiological procedure and radiotherapy
0.754 0.246 0.000
R22.1 Localised swelling, mass and lump, neck
0.753 0.247 0.000
I72 Other aneurysm
0.752 0.248 0.000
Y95 Nosocomial condition
0.751 0.249 0.000
M25.46 Effusion of joint (Lower leg)
0.748 0.252 0.000
M21.3 Wrist or foot drop (acquired)
0.748 0.252 0.000
N39 Other disorders of urinary system
0.748 0.252 0.000
N36 Other disorders of urethra
0.748 0.252 0.000
M25.52 Pain in joint (Upper arm)
0.747 0.253 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.747 0.253 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.746 0.254 0.000
M79.7 Fibromyalgia
0.746 0.254 0.000
M79.64 Pain in limb (Hand)
0.743 0.257 0.000
R01 Cardiac murmurs and other cardiac sounds
0.742 0.258 0.000
S10-S19 Injuries to the neck
0.742 0.258 0.000
M25.86 Other specified joint disorders (Lower leg)
0.741 0.259 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.740 0.260 0.000
V80-V89 Other land transport accidents
0.739 0.261 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.738 0.262 0.000
H55-H59 Other disorders of eye and adnexa
0.736 0.264 0.000
T87 Complications peculiar to reattachment and amputation
0.736 0.264 0.000
M65.3 Trigger finger
0.736 0.264 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.735 0.265 0.000
M86-M90 Other osteopathies
0.734 0.266 0.000
F60-F69 Disorders of adult personality and behaviour
0.734 0.266 0.000
N26 Unspecified contracted kidney
0.733 0.267 0.000
R26 Abnormalities of gait and mobility
0.733 0.267 0.000
Y83.0 Surgical operation with transplant of whole organ
0.733 0.267 0.000
N20.0 Calculus of kidney
0.732 0.268 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.732 0.268 0.000
R06.0 Dyspnoea
0.732 0.268 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.730 0.270 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.730 0.270 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.729 0.271 0.000
T78 Adverse effects, not elsewhere classified
0.729 0.271 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.729 0.271 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.729 0.271 0.000
H33 Retinal detachments and breaks
0.729 0.271 0.000
M60-M63 Disorders of muscles
0.729 0.271 0.000
N10-N16 Renal tubulo-interstitial diseases
0.728 0.272 0.000
I70 Atherosclerosis
0.727 0.273 0.000
Y52.1 Calcium-channel blockers
0.727 0.273 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.725 0.275 0.000
M21.1 Varus deformity, not elsewhere classified
0.724 0.276 0.000
N39.3 Stress incontinence
0.724 0.276 0.000
R21 Rash and other nonspecific skin eruption
0.724 0.276 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.723 0.277 0.000
M67.1 Other contracture of tendon (sheath)
0.723 0.277 0.000
G57 Mononeuropathies of lower limb
0.723 0.277 0.000
M71 Other bursopathies
0.723 0.277 0.000
H54 Blindness and low vision
0.723 0.277 0.000
V20-V29 Motorcycle rider injured in transport accident
0.722 0.277 0.000
R09.1 Pleurisy
0.722 0.278 0.000
N28.8 Other specified disorders of kidney and ureter
0.721 0.279 0.000
I05 Rheumatic mitral valve diseases
0.721 0.279 0.000
T90 Sequelae of injuries of head
0.721 0.279 0.000
M22.4 Chondromalacia patellae
0.720 0.280 0.000
R25 Abnormal involuntary movements
0.720 0.280 0.000
M25.31 Other instability of joint (Shoulder region)
0.720 0.280 0.000
N18.0 End-stage renal disease
0.719 0.281 0.000
G51 Facial nerve disorders
0.719 0.281 0.000
R49.0 Dysphonia
0.719 0.281 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.719 0.281 0.000
M93 Other osteochondropathies
0.718 0.282 0.000
F17.1 Harmful use
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.283 0.000
M34 Systemic sclerosis
0.716 0.283 0.000
M33 Dermatopolymyositis
0.716 0.283 0.000
M32 Systemic lupus erythematosus
0.716 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
M76 Enthesopathies of lower limb, excluding foot
0.716 0.284 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.716 0.284 0.000
V10-V19 Pedal cyclist injured in transport accident
0.716 0.284 0.000
M25.9 Joint disorder, unspecified
0.716 0.284 0.000
M25.2 Flail joint
0.716 0.284 0.000
M25.1 Fistula of joint
0.716 0.284 0.000
M25.0 Haemarthrosis
0.716 0.284 0.000
M79.9 Soft tissue disorder, unspecified
0.715 0.285 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.715 0.285 0.000
M79.3 Panniculitis, unspecified
0.715 0.285 0.000
M79.2 Neuralgia and neuritis, unspecified
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
R22.2 Localised swelling, mass and lump, trunk
0.714 0.286 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.714 0.286 0.000
H20.9 Iridocyclitis, unspecified
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
Q50-Q56 Congenital malformations of genital organs
0.714 0.286 0.000
T86 Failure and rejection of transplanted organs and tissues
0.713 0.286 0.000
Y83.4 Other reconstructive surgery
0.713 0.287 0.000
M79.68 Pain in limb (Other)
0.713 0.287 0.000
M79.61 Pain in limb (Shoulder region)
0.713 0.287 0.000
R32 Unspecified urinary incontinence
0.712 0.288 0.000
T92 Sequelae of injuries of upper limb
0.712 0.288 0.000
G62.9 Polyneuropathy, unspecified
0.712 0.288 0.000
I42.2 Other hypertrophic cardiomyopathy
0.711 0.288 0.000
I50.0 Congestive heart failure
0.711 0.289 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.711 0.289 0.000
H35 Other retinal disorders
0.711 0.289 0.000
I45 Other conduction disorders
0.711 0.289 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.711 0.289 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
M80-M85 Disorders of bone density and structure
0.710 0.290 0.000
T82.1 Mechanical complication of cardiac electronic device
0.709 0.291 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.709 0.291 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.709 0.291 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.709 0.291 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.709 0.291 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.708 0.292 0.000
M25.58 Pain in joint (Other)
0.708 0.292 0.000
S80-S89 Injuries to the knee and lower leg
0.707 0.292 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.707 0.293 0.000
T98 Sequelae of other and unspecified effects of external causes
0.706 0.293 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.706 0.294 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.706 0.294 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.706 0.294 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.704 0.295 0.000
I42.6 Alcoholic cardiomyopathy
0.704 0.295 0.000
I42.5 Other restrictive cardiomyopathy
0.704 0.295 0.000
I42.4 Endocardial fibroelastosis
0.704 0.295 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.704 0.295 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.704 0.295 0.000
H40.1 Primary open-angle glaucoma
0.704 0.296 0.000
G50 Disorders of trigeminal nerve
0.703 0.297 0.000
H42 Glaucoma in diseases classified elsewhere
0.703 0.297 0.000
R47.1 Dysarthria and anarthria
0.702 0.298 0.000
I33.0 Acute and subacute infective endocarditis
0.701 0.299 0.000
I77.5 Necrosis of artery
0.701 0.299 0.000
I77.4 Coeliac artery compression syndrome
0.701 0.299 0.000
I77.3 Arterial fibromuscular dysplasia
0.701 0.299 0.000
I77.2 Rupture of artery
0.701 0.299 0.000
I77.0 Arteriovenous fistula, acquired
0.701 0.299 0.000
R09.0 Asphyxia
0.701 0.299 0.000
R30 Pain associated with micturition
0.701 0.299 0.000
R23.8 Other and unspecified skin changes
0.700 0.300 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.699 0.301 0.000
T93.2 Sequelae of other fractures of lower limb
0.699 0.301 0.000
X60-X84 Intentional self-harm
0.697 0.303 0.000
N18.2 Chronic kidney disease, stage 2
0.697 0.303 0.000
G91 Hydrocephalus
0.697 0.303 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.697 0.303 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.697 0.303 0.000
R47.0 Dysphasia and aphasia
0.696 0.304 0.000
I30 Acute pericarditis
0.695 0.305 0.000
I35.8 Other aortic valve disorders
0.695 0.305 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.694 0.306 0.000
I74.8 Embolism and thrombosis of other arteries
0.694 0.306 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.694 0.306 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.694 0.306 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.694 0.306 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.694 0.306 0.000
H40.8 Other glaucoma
0.694 0.306 0.000
H40.6 Glaucoma secondary to drugs
0.694 0.306 0.000
H40.4 Glaucoma secondary to eye inflammation
0.694 0.306 0.000
H40.3 Glaucoma secondary to eye trauma
0.694 0.306 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.693 0.307 0.000
R20.2 Paraesthesia of skin
0.693 0.307 0.000
R73 Elevated blood glucose level
0.691 0.309 0.000
M79.67 Pain in limb (Ankle and foot)
0.691 0.309 0.000
R06.1 Stridor
0.691 0.309 0.000
M06 Other rheumatoid arthritis
0.690 0.310 0.000
M25.72 Osteophyte (Upper arm)
0.690 0.310 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.690 0.310 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.689 0.311 0.000
I47 Paroxysmal tachycardia
0.689 0.311 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.688 0.312 0.000
N30.1 Interstitial cystitis (chronic)
0.687 0.313 0.000
H53.4 Visual field defects
0.687 0.313 0.000
I51 Complications and ill-defined descriptions of heart disease
0.687 0.313 0.000
G56 Mononeuropathies of upper limb
0.687 0.313 0.000
M77.9 Enthesopathy, unspecified
0.685 0.315 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.684 0.316 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.683 0.317 0.000
N21 Calculus of lower urinary tract
0.683 0.317 0.000
N28.0 Ischaemia and infarction of kidney
0.682 0.318 0.000
Y44 Agents primarily affecting blood constituents
0.682 0.318 0.000
R06.2 Wheezing
0.682 0.318 0.000
N23 Unspecified renal colic
0.681 0.319 0.000
N18.8 Other chronic renal failure
0.680 0.320 0.000
N18.1 Chronic kidney disease, stage 1
0.680 0.320 0.000
Y59 Other and unspecified vaccines and biological substances
0.679 0.320 0.000
Y58 Bacterial vaccines
0.679 0.320 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.679 0.320 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.679 0.320 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.679 0.320 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.679 0.320 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.679 0.320 0.000
Y48 Anaesthetics and therapeutic gases
0.679 0.320 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.679 0.320 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.679 0.320 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.679 0.320 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.678 0.322 0.000
M13 Other arthritis
0.678 0.322 0.000
H10-H13 Disorders of conjunctiva
0.677 0.322 0.000
I44.2 Atrioventricular block, complete
0.677 0.323 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.677 0.323 0.000
H53.0 Amblyopia ex anopsia
0.677 0.323 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.677 0.323 0.000
H43-H45 Disorders of vitreous body and globe
0.676 0.324 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.676 0.324 0.000
Y40 Systemic antibiotics
0.676 0.324 0.000
M24.0 Loose body in joint
0.675 0.324 0.000
S50-S59 Injuries to the elbow and forearm
0.675 0.325 0.000
M79.63 Pain in limb (Forearm)
0.675 0.325 0.000
Y83.5 Amputation of limb(s)
0.674 0.326 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.674 0.326 0.000
I23 Certain current complications following acute myocardial infarction
0.674 0.326 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.674 0.326 0.000
W00-W19 Falls
0.674 0.326 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.674 0.326 0.000
M65.8 Other synovitis and tenosynovitis
0.673 0.326 0.000
M65.2 Calcific tendinitis
0.673 0.326 0.000
M65.1 Other infective (teno)synovitis
0.673 0.326 0.000
M65.0 Abscess of tendon sheath
0.673 0.326 0.000
S40-S49 Injuries to the shoulder and upper arm
0.673 0.327 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.673 0.327 0.000
H33.5 Other retinal detachments
0.673 0.327 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.672 0.328 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.672 0.328 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.671 0.329 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.670 0.329 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.670 0.330 0.000
M31 Other necrotising vasculopathies
0.670 0.330 0.000
T95 Sequelae of burns, corrosions and frostbite
0.670 0.330 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.670 0.330 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.670 0.330 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.670 0.330 0.000
Q00-Q07 Congenital malformations of the nervous system
0.669 0.331 0.000
Y45.1 Salicylates
0.669 0.331 0.000
R76 Other abnormal immunological findings in serum
0.669 0.331 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.668 0.332 0.000
N27 Small kidney of unknown cause
0.668 0.332 0.000
N25 Disorders resulting from impaired renal tubular function
0.668 0.332 0.000
E20-E35 Disorders of other endocrine glands
0.667 0.333 0.000
U80 Agent resistant to penicillin and related antibiotics
0.666 0.334 0.000
H25-H28 Disorders of lens
0.666 0.334 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.666 0.334 0.000
M92 Other juvenile osteochondrosis
0.665 0.334 0.000
G70-G73 Diseases of myoneural junction and muscle
0.665 0.334 0.000
I44.6 Other and unspecified fascicular block
0.665 0.335 0.000
N18.5 Chronic kidney disease, stage 5
0.665 0.335 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.664 0.335 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.664 0.336 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.664 0.336 0.000
H05 Disorders of orbit
0.664 0.336 0.000
M79.10 Myalgia (Multiple sites)
0.664 0.336 0.000
N18.3 Chronic kidney disease, stage 3
0.664 0.336 0.000
M50-M54 Other dorsopathies
0.663 0.337 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.662 0.338 0.000
R81 Glycosuria
0.661 0.339 0.000
S91 Open wound of ankle and foot
0.661 0.339 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.661 0.339 0.000
M94 Other disorders of cartilage
0.660 0.340 0.000
R39 Other symptoms and signs involving the urinary system
0.660 0.340 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.659 0.341 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.658 0.341 0.000
Y45.2 Propionic acid derivatives
0.658 0.342 0.000
M35.0 Sicca syndrome [Sjogren]
0.658 0.342 0.000
R82 Other abnormal findings in urine
0.658 0.342 0.000
M40-M43 Deforming dorsopathies
0.657 0.342 0.000
R36 Urethral discharge
0.657 0.343 0.000
R34 Anuria and oliguria
0.657 0.343 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.657 0.343 0.000
I08.0 Disorders of both mitral and aortic valves
0.656 0.344 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.656 0.344 0.000
R06.6 Hiccough
0.656 0.344 0.000
R85.5 Abnormal microbiological findings
0.655 0.345 0.000
I09 Other rheumatic heart diseases
0.655 0.345 0.000
I06 Rheumatic aortic valve diseases
0.655 0.345 0.000
M77.0 Medial epicondylitis
0.652 0.348 0.000
T20 Burn and corrosion of head and neck
0.651 0.349 0.000
R94 Abnormal results of function studies
0.651 0.349 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.649 0.350 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.648 0.352 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.648 0.352 0.000
M67.4 Ganglion
0.648 0.352 0.000
M67.3 Transient synovitis
0.648 0.352 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.648 0.352 0.000
M67.0 Short Achilles tendon (acquired)
0.648 0.352 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.647 0.353 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.645 0.355 0.000
G58 Other mononeuropathies
0.645 0.355 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.644 0.355 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.644 0.355 0.000
M25.59 Pain in joint (Site unspecified)
0.644 0.356 0.000
H35.3 Degeneration of macula and posterior pole
0.643 0.357 0.000
N30.9 Cystitis, unspecified
0.643 0.357 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.642 0.358 0.000
M79.5 Residual foreign body in soft tissue
0.641 0.358 0.000
M24.1 Other articular cartilage disorders
0.640 0.360 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.640 0.360 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.640 0.360 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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