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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117744271
log Bayes Factor = 7.2886
Chromosome 7   position 132,152,409  (GRCh37) Explore rs117744271 on Ensembl!
Variant rs117744271 is part of Cluster X0079

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Chapter II Neoplasms
0.986 0.014 0.000
M15-M19 Arthrosis
0.985 0.015 0.000
E11.9 Without complications
0.982 0.018 0.000
E14 Unspecified diabetes mellitus
0.979 0.021 0.000
E00-E07 Disorders of thyroid gland
0.977 0.023 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.973 0.027 0.000
E11.3 With ophthalmic complications
0.972 0.028 0.000
M16 Coxarthrosis [arthrosis of hip]
0.972 0.028 0.000
E14.9 Without complications
0.967 0.033 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.951 0.049 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.950 0.050 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.950 0.050 0.000
Chapter XX External causes of morbidity and mortality
0.946 0.054 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.943 0.057 0.000
M50-M54 Other dorsopathies
0.941 0.059 0.000
Chapter VIII Diseases of the ear and mastoid process
0.938 0.062 0.000
M20-M25 Other joint disorders
0.936 0.064 0.000
M16.1 Other primary coxarthrosis
0.934 0.066 0.000
M51 Other intervertebral disk disorders
0.926 0.074 0.000
M45-M49 Spondylopathies
0.925 0.075 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.922 0.078 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.916 0.084 0.000
M16.0 Primary coxarthrosis, bilateral
0.915 0.085 0.000
G35 Multiple sclerosis
0.909 0.091 0.000
M51.2 Other specified intervertebral disk displacement
0.909 0.091 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.896 0.104 0.000
E11.2 With renal complications
0.896 0.104 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.893 0.107 0.000
C79 Secondary malignant neoplasm of other sites
0.892 0.108 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.891 0.109 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.886 0.114 0.000
G54 Nerve root and plexus disorders
0.882 0.118 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.881 0.119 0.000
E05.9 Thyrotoxicosis, unspecified
0.879 0.121 0.000
M24 Other specific joint derangements
0.877 0.123 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.876 0.124 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.870 0.130 0.000
E11.4 With neurological complications
0.866 0.134 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.864 0.136 0.000
E06 Thyroiditis
0.860 0.140 0.000
E50-E64 Other nutritional deficiencies
0.856 0.144 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.855 0.145 0.000
C64-C68 Malignant neoplasms of urinary tract
0.854 0.145 0.000
M25 Other joint disorders, not elsewhere classified
0.854 0.146 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.849 0.151 0.000
M45 Ankylosing spondylitis
0.845 0.155 0.000
C60-C63 Malignant neoplasms of male genital organs
0.844 0.156 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.842 0.158 0.000
E05.8 Other thyrotoxicosis
0.841 0.159 0.000
G40-G47 Episodic and paroxysmal disorders
0.839 0.161 0.000
S32 Fracture of lumbar spine and pelvis
0.835 0.165 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.834 0.166 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.832 0.168 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.828 0.172 0.000
C01 Malignant neoplasm of base of tongue
0.825 0.175 0.000
Chapter XXI Factors influencing health status and contact with health services
0.820 0.180 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.819 0.181 0.000
C67 Malignant neoplasm of bladder
0.814 0.186 0.000
Y52 Agents primarily affecting the cardiovascular system
0.807 0.193 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.806 0.194 0.000
H65-H75 Diseases of middle ear and mastoid
0.804 0.196 0.000
M16.3 Other dysplastic coxarthrosis
0.804 0.196 0.000
M23 Internal derangement of knee
0.804 0.196 0.000
M51.9 Intervertebral disk disorder, unspecified
0.803 0.197 0.000
H60-H62 Diseases of external ear
0.803 0.197 0.000
M16.7 Other secondary coxarthrosis
0.800 0.200 0.000
G20-G26 Extrapyramidal and movement disorders
0.791 0.209 0.000
M86-M90 Other osteopathies
0.791 0.209 0.000
M15 Polyarthrosis
0.790 0.210 0.000
G43 Migraine
0.789 0.211 0.000
G83 Other paralytic syndromes
0.788 0.212 0.000
Chapter XXII Codes for special purposes
0.788 0.212 0.000
E11.5 With peripheral circulatory complications
0.783 0.217 0.000
E03 Other hypothyroidism
0.780 0.220 0.000
E61 Deficiency of other nutrient elements
0.780 0.220 0.000
G54.8 Other nerve root and plexus disorders
0.778 0.222 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.778 0.222 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.777 0.223 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.776 0.224 0.000
E06.3 Autoimmune thyroiditis
0.776 0.224 0.000
W00-W19 Falls
0.775 0.225 0.000
E20-E35 Disorders of other endocrine glands
0.775 0.225 0.000
M34 Systemic sclerosis
0.774 0.226 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.774 0.226 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.773 0.227 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.773 0.227 0.000
M23.8 Other internal derangements of knee
0.770 0.230 0.000
W50-W64 Exposure to animate mechanical forces
0.769 0.231 0.000
D41.4 Bladder
0.769 0.231 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.767 0.233 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.765 0.235 0.000
X60-X84 Intentional self-harm
0.763 0.237 0.000
M00-M03 Infectious arthropathies
0.762 0.238 0.000
M51.8 Other specified intervertebral disk disorders
0.762 0.238 0.000
C73 Malignant neoplasm of thyroid gland
0.762 0.238 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.758 0.242 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.755 0.245 0.000
C85.1 B-cell lymphoma, unspecified
0.753 0.247 0.000
C92 Myeloid leukaemia
0.753 0.247 0.000
Y86 Sequelae of other accidents
0.752 0.248 0.000
G57 Mononeuropathies of lower limb
0.749 0.251 0.000
M48 Other spondylopathies
0.748 0.252 0.000
M19 Other arthrosis
0.748 0.252 0.000
M60-M63 Disorders of muscles
0.747 0.253 0.000
T93 Sequelae of injuries of lower limb
0.747 0.253 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.747 0.253 0.000
G50 Disorders of trigeminal nerve
0.746 0.254 0.000
C51-C58 Malignant neoplasms of female genital organs
0.745 0.255 0.000
S36 Injury of intra-abdominal organs
0.745 0.255 0.000
C67.2 Lateral wall of bladder
0.744 0.256 0.000
S10-S19 Injuries to the neck
0.744 0.256 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.744 0.256 0.000
M17 Gonarthrosis [arthrosis of knee]
0.742 0.258 0.000
E11.0 With coma
0.741 0.258 0.000
Y44 Agents primarily affecting blood constituents
0.740 0.260 0.000
M46 Other inflammatory spondylopathies
0.739 0.261 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.738 0.262 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.737 0.262 0.000
G37 Other demyelinating diseases of central nervous system
0.737 0.263 0.000
E13 Other specified diabetes mellitus
0.737 0.263 0.000
Y40 Systemic antibiotics
0.736 0.264 0.000
E40-E46 Malnutrition
0.736 0.264 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.736 0.264 0.000
H90-H95 Other disorders of ear
0.734 0.265 0.000
G59.0 Diabetic mononeuropathy
0.734 0.266 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.733 0.267 0.000
Z02 Examination and encounter for administrative purposes
0.731 0.269 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.731 0.269 0.000
E11.1 With ketoacidosis
0.730 0.270 0.000
Z02.8 Other examinations for administrative purposes
0.730 0.270 0.000
E61.1 Iron deficiency
0.725 0.274 0.000
X50-X57 Overexertion, travel and privation
0.724 0.275 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.724 0.276 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.723 0.277 0.000
M25.4 Effusion of joint
0.721 0.279 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.719 0.281 0.000
M24.6 Ankylosis of joint
0.718 0.282 0.000
S32.5 Fracture of pubis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
M24.2 Disorder of ligament
0.716 0.284 0.000
D46 Myelodysplastic syndromes
0.716 0.284 0.000
M21 Other acquired deformities of limbs
0.716 0.284 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
M80-M85 Disorders of bone density and structure
0.715 0.285 0.000
M25.7 Osteophyte
0.714 0.286 0.000
H80-H83 Diseases of inner ear
0.714 0.286 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.713 0.287 0.000
M24.1 Other articular cartilage disorders
0.712 0.288 0.000
T66-T78 Other and unspecified effects of external causes
0.712 0.288 0.000
G90-G99 Other disorders of the nervous system
0.711 0.289 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.711 0.289 0.000
M17.9 Gonarthrosis, unspecified
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.707 0.292 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.707 0.293 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.707 0.293 0.000
G43.9 Migraine, unspecified
0.705 0.295 0.000
Z29 Need for other prophylactic measures
0.705 0.295 0.000
H65 Nonsuppurative otitis media
0.704 0.296 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.704 0.296 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.704 0.296 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
G44 Other headache syndromes
0.703 0.297 0.000
E14.8 With unspecified complications
0.702 0.298 0.000
E14.7 With multiple complications
0.702 0.298 0.000
E14.6 With other specified complications
0.702 0.298 0.000
E14.5 With peripheral circulatory complications
0.702 0.298 0.000
E14.4 With neurological complications
0.702 0.298 0.000
E14.2 Withrenal complications
0.702 0.298 0.000
E14.1 With ketoacidosis
0.702 0.298 0.000
E14.0 With coma
0.702 0.298 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.702 0.298 0.000
D70 Agranulocytosis
0.701 0.299 0.000
M50 Cervical disk disorders
0.701 0.299 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.700 0.299 0.000
E00 Congenital iodine-deficiency syndrome
0.700 0.299 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.700 0.299 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.700 0.300 0.000
M40-M43 Deforming dorsopathies
0.700 0.300 0.000
M19.0 Primary arthrosis of other joints
0.699 0.301 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.698 0.302 0.000
G52 Disorders of other cranial nerves
0.698 0.302 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.698 0.302 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.697 0.303 0.000
M16.5 Other posttraumatic coxarthrosis
0.697 0.303 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.697 0.303 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.697 0.303 0.000
G70-G73 Diseases of myoneural junction and muscle
0.696 0.303 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.696 0.304 0.000
M24.5 Contracture of joint
0.696 0.304 0.000
M25.0 Haemarthrosis
0.695 0.305 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.694 0.306 0.000
G43.1 Migraine with aura [classical migraine]
0.694 0.306 0.000
T91 Sequelae of injuries of neck and trunk
0.693 0.307 0.000
D41.0 Kidney
0.692 0.308 0.000
C79.2 Secondary malignant neoplasm of skin
0.692 0.308 0.000
S50-S59 Injuries to the elbow and forearm
0.691 0.309 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.691 0.309 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.690 0.310 0.000
G58 Other mononeuropathies
0.689 0.311 0.000
S90-S99 Injuries to the ankle and foot
0.687 0.312 0.000
D45 Polycythaemia vera
0.687 0.313 0.000
G80 Infantile cerebral palsy
0.686 0.314 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.686 0.314 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.686 0.314 0.000
D60-D64 Aplastic and other anaemias
0.684 0.316 0.000
C88 Malignant immunoproliferative diseases
0.684 0.316 0.000
W20-W49 Exposure to inanimate mechanical forces
0.684 0.316 0.000
S20-S29 Injuries to the thorax
0.684 0.316 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.684 0.316 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.683 0.316 0.000
E03.8 Other specified hypothyroidism
0.683 0.317 0.000
M25.9 Joint disorder, unspecified
0.683 0.317 0.000
C67.6 Ureteric orifice
0.682 0.318 0.000
G36 Other acute disseminated demyelination
0.682 0.318 0.000
E05.5 Thyroid crisis or storm
0.681 0.318 0.000
E05.4 Thyrotoxicosis factitia
0.681 0.318 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.681 0.318 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.681 0.318 0.000
C10 Malignant neoplasm of oropharynx
0.681 0.319 0.000
Q60-Q64 Congenital malformations of the urinary system
0.681 0.319 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.681 0.319 0.000
C95 Leukaemia of unspecified cell type
0.681 0.319 0.000
C94 Other leukaemias of specified cell type
0.681 0.319 0.000
C93 Monocytic leukaemia
0.681 0.319 0.000
C86 Other specified types of T/NK-cell lymphoma
0.681 0.319 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.681 0.319 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.681 0.319 0.000
C67.1 Dome of bladder
0.680 0.320 0.000
T79-T79 Certain early complications of trauma
0.679 0.321 0.000
Y35-Y36 Legal intervention and operations of war
0.679 0.321 0.000
Y10-Y34 Event of undetermined intent
0.679 0.321 0.000
Y00-Y09 Assault
0.679 0.321 0.000
X85-X99 Assault
0.679 0.321 0.000
X30-X39 Exposure to forces of nature
0.679 0.321 0.000
X20-X29 Contact with venomous animals and plants
0.679 0.321 0.000
X10-X19 Contact with heat and hot substances
0.679 0.321 0.000
X00-X09 Exposure to smoke, fire and flames
0.679 0.321 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.679 0.321 0.000
W75-W84 Other accidental threats to breathing
0.679 0.321 0.000
W65-W74 Accidental drowning and submersion
0.679 0.321 0.000
V98-V99 Other and unspecified transport accidents
0.679 0.321 0.000
V95-V97 Air and space transport accidents
0.679 0.321 0.000
V90-V94 Water transport accidents
0.679 0.321 0.000
V70-V79 Bus occupant injured in transport accident
0.679 0.321 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.679 0.321 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.679 0.321 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.679 0.321 0.000
V01-V09 Pedestrian injured in transport accident
0.679 0.321 0.000
S30.1 Contusion of abdominal wall
0.676 0.324 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.676 0.324 0.000
T33-T35 Frostbite
0.676 0.324 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.676 0.324 0.000
T00-T07 Injuries involving multiple body regions
0.676 0.324 0.000
Q50-Q56 Congenital malformations of genital organs
0.674 0.326 0.000
C60 Malignant neoplasm of penis
0.674 0.326 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.674 0.326 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.672 0.328 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.671 0.329 0.000
M33 Dermatopolymyositis
0.671 0.329 0.000
M32 Systemic lupus erythematosus
0.671 0.329 0.000
M30 Polyarteritis nodosa and related conditions
0.671 0.329 0.000
M91-M94 Chondropathies
0.671 0.329 0.000
D66 Hereditary factor VIII deficiency
0.668 0.332 0.000
V80-V89 Other land transport accidents
0.668 0.332 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.668 0.332 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.667 0.333 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.667 0.333 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.667 0.333 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.666 0.333 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.666 0.334 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.665 0.334 0.000
H60 Otitis externa
0.664 0.336 0.000
M51.3 Other specified intervertebral disk degeneration
0.664 0.336 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.664 0.336 0.000
M51.4 Schmorl's nodes
0.664 0.336 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.664 0.336 0.000
M49 Spondylopathies in diseases classified elsewhere
0.663 0.337 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.663 0.337 0.000
M23.9 Internal derangement of knee, unspecified
0.662 0.338 0.000
G25 Other extrapyramidal and movement disorders
0.662 0.338 0.000
C81 Hodgkin's disease
0.661 0.339 0.000
S30.0 Contusion of lower back and pelvis
0.661 0.339 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.661 0.339 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.660 0.340 0.000
G82 Paraplegia and tetraplegia
0.660 0.340 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.660 0.340 0.000
C62 Malignant neoplasm of testis
0.659 0.341 0.000
C61 Malignant neoplasm of prostate
0.658 0.342 0.000
Z29.2 Other prophylactic chemotherapy
0.658 0.342 0.000
S60-S69 Injuries to the wrist and hand
0.658 0.342 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.657 0.343 0.000
S37 Injury of urinary and pelvic organs
0.657 0.343 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.657 0.343 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.657 0.343 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.657 0.343 0.000
S31 Open wound of abdomen, lower back and pelvis
0.657 0.343 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.657 0.343 0.000
M53 Other dorsopathies, not elsewhere classified
0.656 0.344 0.000
S32.3 Fracture of ilium
0.656 0.344 0.000
V40-V49 Car occupant injured in transport accident
0.656 0.344 0.000
G83.2 Monoplegia of upper limb
0.655 0.345 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.654 0.345 0.000
G91 Hydrocephalus
0.654 0.346 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.653 0.346 0.000
M24.0 Loose body in joint
0.653 0.347 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.652 0.348 0.000
S40-S49 Injuries to the shoulder and upper arm
0.651 0.349 0.000
M15.9 Polyarthrosis, unspecified
0.651 0.349 0.000
Chapter IX Diseases of the circulatory system
0.651 0.349 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.650 0.349 0.000
M25.78 Osteophyte (Other)
0.651 0.349 0.000
C15-C26 Malignant neoplasms of digestive organs
0.649 0.351 0.000
G51 Facial nerve disorders
0.649 0.351 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.649 0.351 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.649 0.351 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.648 0.352 0.000
E14.3 With ophthalmic complications
0.647 0.352 0.000
Y44.2 Anticoagulants
0.647 0.353 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.647 0.353 0.000
G30-G32 Other degenerative diseases of the nervous system
0.646 0.354 0.000
H90 Conductive and sensorineural hearing loss
0.646 0.354 0.000
I95 Hypotension
0.646 0.354 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.645 0.355 0.000
V20-V29 Motorcycle rider injured in transport accident
0.645 0.355 0.000
G83.4 Cauda equina syndrome
0.644 0.356 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.644 0.356 0.000
C83.1 Small cleaved cell (diffuse)
0.644 0.356 0.000
H61 Other disorders of external ear
0.643 0.357 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.642 0.357 0.000
S32.0 Fracture of lumbar vertebra
0.642 0.358 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.640 0.360 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.640 0.360 0.000
C13 Malignant neoplasm of hypopharynx
0.640 0.360 0.000
C11 Malignant neoplasm of nasopharynx
0.640 0.360 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.640 0.360 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.640 0.360 0.000
C05 Malignant neoplasm of palate
0.640 0.360 0.000
C04 Malignant neoplasm of floor of mouth
0.640 0.360 0.000
C03 Malignant neoplasm of gum
0.640 0.360 0.000
C00 Malignant neoplasm of lip
0.640 0.360 0.000
C12 Malignant neoplasm of pyriform sinus
0.640 0.360 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.639 0.361 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.639 0.361 0.000
C85.0 Lymphosarcoma
0.639 0.361 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.639 0.361 0.000
C07 Malignant neoplasm of parotid gland
0.638 0.362 0.000
D69 Purpura and other haemorrhagic conditions
0.638 0.362 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.637 0.363 0.000
G56 Mononeuropathies of upper limb
0.637 0.363 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.637 0.363 0.000
Y40.0 Penicillins
0.636 0.364 0.000
M34.9 Systemic sclerosis, unspecified
0.635 0.365 0.000
S32.50 Fracture of pubis (closed)
0.633 0.367 0.000
G54.7 Phantom limb syndrome without pain
0.633 0.367 0.000
G54.6 Phantom limb syndrome with pain
0.633 0.367 0.000
G54.5 Neuralgic amyotrophy
0.633 0.367 0.000
G54.3 Thoracic root disorders, not elsewhere classified
0.633 0.367 0.000
G54.2 Cervical root disorders, not elsewhere classified
0.633 0.367 0.000
G54.1 Lumbosacral plexus disorders
0.633 0.367 0.000
S70-S79 Injuries to the hip and thigh
0.633 0.367 0.000
T92 Sequelae of injuries of upper limb
0.632 0.368 0.000
M70-M79 Other soft tissue disorders
0.631 0.369 0.000
C79.6 Secondary malignant neoplasm of ovary
0.631 0.369 0.000
M89 Other disorders of bone
0.630 0.370 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.629 0.371 0.000
E11.6 With other specified complications
0.629 0.371 0.000
M24.9 Joint derangement, unspecified
0.629 0.371 0.000
M24.7 Protrusio acetabuli
0.629 0.371 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.629 0.371 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.629 0.371 0.000
I95.9 Hypotension, unspecified
0.628 0.372 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.628 0.372 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.628 0.372 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.627 0.372 0.000
H74 Other disorders of middle ear and mastoid
0.627 0.373 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.627 0.373 0.000
Q00-Q07 Congenital malformations of the nervous system
0.626 0.373 0.000
C67.3 Anterior wall of bladder
0.625 0.375 0.000
Q80-Q89 Other congenital malformations
0.625 0.375 0.000
C65 Malignant neoplasm of renal pelvis
0.625 0.375 0.000
W10 Fall on and from stairs and steps
0.625 0.375 0.000
Y59 Other and unspecified vaccines and biological substances
0.624 0.376 0.000
Y58 Bacterial vaccines
0.624 0.376 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.624 0.376 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.624 0.376 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.624 0.376 0.000
Y48 Anaesthetics and therapeutic gases
0.624 0.376 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.624 0.376 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.624 0.376 0.000
D47.1 Chronic myeloproliferative disease
0.623 0.377 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.623 0.377 0.000
M31 Other necrotising vasculopathies
0.622 0.378 0.000
S32.1 Fracture of sacrum
0.621 0.379 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.621 0.379 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.620 0.380 0.000
M86 Osteomyelitis
0.620 0.380 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.619 0.381 0.000
Q35-Q37 Cleft lip and cleft palate
0.619 0.381 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.619 0.381 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.619 0.381 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.619 0.381 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.618 0.382 0.000
Y52.1 Calcium-channel blockers
0.618 0.382 0.000
G50.1 Atypical facial pain
0.618 0.382 0.000
S32.4 Fracture of acetabulum
0.618 0.382 0.000
M50.2 Other cervical disk displacement
0.618 0.382 0.000
C80 Malignant neoplasm without specification of site
0.617 0.383 0.000
E06.9 Thyroiditis, unspecified
0.616 0.383 0.000
E06.5 Other chronic thyroiditis
0.616 0.383 0.000
E06.4 Drug-induced thyroiditis
0.616 0.383 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.616 0.383 0.000
E06.1 Subacute thyroiditis
0.616 0.383 0.000
E06.0 Acute thyroiditis
0.616 0.383 0.000
U88 Agent resistant to multiple antibiotics
0.616 0.384 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.615 0.385 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.614 0.386 0.000
C92.1 Chronic myeloid leukaemia
0.614 0.386 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.614 0.386 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.614 0.386 0.000
E63 Other nutritional deficiencies
0.614 0.386 0.000
E56 Other vitamin deficiencies
0.614 0.386 0.000
E51 Thiamine deficiency
0.614 0.386 0.000
E50 Vitamin A deficiency
0.614 0.386 0.000
E60 Dietary zinc deficiency
0.614 0.386 0.000
E59 Dietary selenium deficiency
0.614 0.386 0.000
E58 Dietary calcium deficiency
0.614 0.386 0.000
E54 Ascorbic acid deficiency
0.614 0.386 0.000
E52 Niacin deficiency [pellagra]
0.614 0.386 0.000
V10-V19 Pedal cyclist injured in transport accident
0.614 0.386 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.613 0.387 0.000
C74 Malignant neoplasm of adrenal gland
0.613 0.387 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.613 0.387 0.000
C66 Malignant neoplasm of ureter
0.613 0.387 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.613 0.387 0.000
G91.9 Hydrocephalus, unspecified
0.612 0.387 0.000
M25.2 Flail joint
0.612 0.388 0.000
M25.1 Fistula of joint
0.612 0.388 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.611 0.389 0.000
T93.0 Sequelae of open wound of lower limb
0.611 0.389 0.000
M25.47 Effusion of joint (Ankle and foot)
0.611 0.389 0.000
Z13 Special screening examination for other diseases and disorders
0.610 0.390 0.000
W15 Fall from cliff
0.610 0.390 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.610 0.390 0.000
H83 Other diseases of inner ear
0.610 0.390 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.610 0.390 0.000
E65-E68 Obesity and other hyperalimentation
0.609 0.391 0.000
D41.9 Urinary organ, unspecified
0.608 0.391 0.000
D41.7 Other urinary organs
0.608 0.391 0.000
D41.3 Urethra
0.608 0.391 0.000
D41.2 Ureter
0.608 0.391 0.000
D41.1 Renal pelvis
0.608 0.391 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.608 0.392 0.000
Chapter I Certain infectious and parasitic diseases
0.608 0.392 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.607 0.393 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.606 0.394 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.606 0.394 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.606 0.394 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.606 0.394 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.606 0.394 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.606 0.394 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.606 0.394 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.606 0.394 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.606 0.394 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.606 0.394 0.000
E34 Other endocrine disorders
0.605 0.395 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.605 0.395 0.000
G83.1 Monoplegia of lower limb
0.605 0.395 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.605 0.395 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.604 0.396 0.000
S36.8 Injury of other intra-abdominal organs
0.603 0.397 0.000
I95.1 Orthostatic hypotension
0.603 0.397 0.000
G54.0 Brachial plexus disorders
0.602 0.398 0.000
G57.6 Lesion of plantar nerve
0.602 0.398 0.000
G41 Status epilepticus
0.601 0.399 0.000
Z22 Carrier of infectious disease
0.601 0.399 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.601 0.399 0.000
E23 Hypofunction and other disorders of pituitary gland
0.600 0.400 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.600 0.400 0.000
G81 Hemiplegia
0.600 0.400 0.000
T36 Poisoning by systemic antibiotics
0.600 0.400 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.599 0.401 0.000
S32.2 Fracture of coccyx
0.599 0.401 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.599 0.401 0.000
H71 Cholesteatoma of middle ear
0.599 0.401 0.000
G59.8 Other mononeuropathies in diseases classified elsewhere
0.598 0.402 0.000
D44.1 Adrenal gland
0.597 0.403 0.000
T95 Sequelae of burns, corrosions and frostbite
0.597 0.403 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.597 0.403 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.597 0.403 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.597 0.403 0.000
C54 Malignant neoplasm of corpus uteri
0.595 0.405 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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