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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117772358
log Bayes Factor = 7.09414
Chromosome 18   position 42,348,576  (GRCh37) Explore rs117772358 on Ensembl!
Variant rs117772358 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.994 0.006 0.000
M20 Acquired deformities of fingers and toes
0.992 0.008 0.000
M20.5 Other deformities of toe(s) (acquired)
0.989 0.011 0.000
I26 Pulmonary embolism
0.989 0.011 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.987 0.013 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.985 0.015 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.983 0.017 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.982 0.018 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.982 0.018 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.979 0.021 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.971 0.029 0.000
J90-J94 Other diseases of pleura
0.968 0.032 0.000
I77 Other disorders of arteries and arterioles
0.962 0.038 0.000
M05-M14 Inflammatory polyarthropathies
0.956 0.044 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.954 0.046 0.000
M80-M85 Disorders of bone density and structure
0.952 0.048 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.948 0.052 0.000
J95-J99 Other diseases of the respiratory system
0.946 0.054 0.000
S80-S89 Injuries to the knee and lower leg
0.946 0.054 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.944 0.056 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.943 0.057 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.938 0.062 0.000
I60-I69 Cerebrovascular diseases
0.938 0.062 0.000
J20-J22 Other acute lower respiratory infections
0.930 0.070 0.000
M10 Gout
0.930 0.070 0.000
I05-I09 Chronic rheumatic heart diseases
0.925 0.075 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.914 0.086 0.000
T82.3 Mechanical complication of other vascular grafts
0.913 0.087 0.000
M10.9 Gout, unspecified
0.911 0.089 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.905 0.095 0.000
J93 Pneumothorax
0.902 0.098 0.000
J09-J18 Influenza and pneumonia
0.902 0.098 0.000
I77.6 Arteritis, unspecified
0.891 0.109 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.890 0.110 0.000
M86-M90 Other osteopathies
0.887 0.112 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.886 0.114 0.000
J22 Unspecified acute lower respiratory infection
0.883 0.117 0.000
J94 Other pleural conditions
0.880 0.120 0.000
M20.2 Hallux rigidus
0.880 0.120 0.000
S10-S19 Injuries to the neck
0.877 0.123 0.000
T79-T79 Certain early complications of trauma
0.875 0.125 0.000
I78 Diseases of capillaries
0.875 0.125 0.000
I69 Sequelae of cerebrovascular disease
0.873 0.127 0.000
M24 Other specific joint derangements
0.872 0.128 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.871 0.129 0.000
S81 Open wound of lower leg
0.869 0.131 0.000
I70 Atherosclerosis
0.867 0.133 0.000
T23 Burn and corrosion of wrist and hand
0.863 0.137 0.000
M40-M43 Deforming dorsopathies
0.860 0.140 0.000
M10.99 Gout, unspecified (Site unspecified)
0.851 0.149 0.000
I60 Subarachnoid haemorrhage
0.851 0.149 0.000
Chapter XXII Codes for special purposes
0.850 0.149 0.000
M31 Other necrotising vasculopathies
0.850 0.150 0.000
I61 Intracerebral haemorrhage
0.849 0.151 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.849 0.151 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.847 0.153 0.000
M15-M19 Arthrosis
0.847 0.153 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.845 0.155 0.000
T36 Poisoning by systemic antibiotics
0.841 0.159 0.000
M81 Osteoporosis without pathological fracture
0.840 0.160 0.000
M65-M68 Disorders of synovium and tendon
0.838 0.162 0.000
Q38.7 Pharyngeal pouch
0.837 0.163 0.000
T21 Burn and corrosion of trunk
0.836 0.164 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.832 0.168 0.000
M89 Other disorders of bone
0.832 0.168 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.827 0.173 0.000
I07 Rheumatic tricuspid valve diseases
0.824 0.176 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.824 0.176 0.000
M21 Other acquired deformities of limbs
0.823 0.177 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.822 0.178 0.000
M80 Osteoporosis with pathological fracture
0.820 0.180 0.000
S20-S29 Injuries to the thorax
0.820 0.180 0.000
S81.9 Open wound of lower leg, part unspecified
0.819 0.181 0.000
S80 Superficial injury of lower leg
0.818 0.182 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.815 0.185 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.815 0.185 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.813 0.187 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.812 0.188 0.000
J90 Pleural effusion, not elsewhere classified
0.809 0.191 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.805 0.195 0.000
I77.1 Stricture of artery
0.804 0.196 0.000
Q80-Q89 Other congenital malformations
0.801 0.199 0.000
T39.1 4-Aminophenol derivatives
0.801 0.199 0.000
Q43 Other congenital malformations of intestine
0.800 0.200 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.799 0.201 0.000
M15 Polyarthrosis
0.799 0.201 0.000
I05 Rheumatic mitral valve diseases
0.797 0.203 0.000
J94.8 Other specified pleural conditions
0.794 0.206 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.793 0.207 0.000
M19 Other arthrosis
0.793 0.207 0.000
J93.8 Other pneumothorax
0.791 0.209 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.790 0.210 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.789 0.211 0.000
M31.3 Wegener's granulomatosis
0.789 0.211 0.000
J10 Influenza due to identified influenza virus
0.788 0.212 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.786 0.214 0.000
I27 Other pulmonary heart diseases
0.786 0.214 0.000
T87 Complications peculiar to reattachment and amputation
0.785 0.215 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.785 0.215 0.000
Chapter I Certain infectious and parasitic diseases
0.782 0.218 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.779 0.221 0.000
M30 Polyarteritis nodosa and related conditions
0.778 0.222 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.778 0.222 0.000
M24.5 Contracture of joint
0.776 0.224 0.000
M24.0 Loose body in joint
0.775 0.225 0.000
I95 Hypotension
0.771 0.229 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.771 0.229 0.000
T20 Burn and corrosion of head and neck
0.770 0.230 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.770 0.230 0.000
M19.9 Arthrosis, unspecified
0.769 0.231 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.768 0.232 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.766 0.234 0.000
M05 Seropositive rheumatoid arthritis
0.765 0.235 0.000
M65 Synovitis and tenosynovitis
0.765 0.235 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.762 0.238 0.000
M81.9 Osteoporosis, unspecified
0.761 0.239 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.761 0.239 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.761 0.239 0.000
R25 Abnormal involuntary movements
0.761 0.239 0.000
S86 Injury of muscle and tendon at lower leg level
0.760 0.240 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.760 0.240 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.760 0.240 0.000
M91-M94 Chondropathies
0.758 0.242 0.000
J99.0 Rheumatoid lung disease
0.758 0.242 0.000
Chapter VI Diseases of the nervous system
0.757 0.243 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.756 0.244 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.756 0.244 0.000
M10.96 Gout, unspecified (Lower leg)
0.756 0.244 0.000
B35-B49 Mycoses
0.756 0.244 0.000
T83.2 Mechanical complication of graft of urinary organ
0.755 0.244 0.000
Chapter XX External causes of morbidity and mortality
0.755 0.245 0.000
S82 Fracture of lower leg, including ankle
0.754 0.246 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.752 0.248 0.000
I07.1 Tricuspid insufficiency
0.751 0.249 0.000
Q60-Q64 Congenital malformations of the urinary system
0.750 0.250 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.750 0.250 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.750 0.250 0.000
M43 Other deforming dorsopathies
0.748 0.252 0.000
Chapter VIII Diseases of the ear and mastoid process
0.748 0.252 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.747 0.253 0.000
R26 Abnormalities of gait and mobility
0.747 0.253 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.747 0.253 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.747 0.253 0.000
M65.3 Trigger finger
0.746 0.254 0.000
M10.90 Gout, unspecified (Multiple sites)
0.744 0.255 0.000
I77.8 Other specified disorders of arteries and arterioles
0.743 0.257 0.000
M32 Systemic lupus erythematosus
0.741 0.259 0.000
T36.0 Penicillins
0.740 0.260 0.000
J93.9 Pneumothorax, unspecified
0.740 0.260 0.000
I95.1 Orthostatic hypotension
0.740 0.260 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.739 0.261 0.000
M33 Dermatopolymyositis
0.738 0.262 0.000
M85 Other disorders of bone density and structure
0.738 0.262 0.000
M06 Other rheumatoid arthritis
0.737 0.263 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.735 0.265 0.000
M84 Disorders of continuity of bone
0.735 0.265 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.734 0.266 0.000
M65.34 Trigger finger-Hand
0.733 0.267 0.000
S12 Fracture of neck
0.732 0.268 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.730 0.270 0.000
J93.1 Other spontaneous pneumothorax
0.729 0.271 0.000
J80 Adult respiratory distress syndrome
0.728 0.271 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.727 0.273 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.726 0.274 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.723 0.277 0.000
I78.8 Other diseases of capillaries
0.723 0.277 0.000
M19.98 Arthrosis, unspecified (Other)
0.722 0.278 0.000
M89.8 Other specified disorders of bone
0.722 0.278 0.000
T21.0 Burn of unspecified degree of trunk
0.721 0.279 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.720 0.279 0.000
S27 Injury of other and unspecified intrathoracic organs
0.720 0.280 0.000
T00-T07 Injuries involving multiple body regions
0.719 0.281 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.719 0.281 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.719 0.281 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.718 0.282 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.718 0.282 0.000
B44 Aspergillosis
0.717 0.283 0.000
M15.1 Heberden's nodes (with arthropathy)
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I71 Aortic aneurysm and dissection
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.717 0.283 0.000
I99 Other and unspecified disorders of circulatory system
0.716 0.284 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.716 0.284 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.715 0.284 0.000
I30-I52 Other forms of heart disease
0.715 0.285 0.000
Q44.6 Cystic disease of liver
0.715 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.286 0.000
I28 Other diseases of pulmonary vessels
0.713 0.287 0.000
J91 Pleural effusion in conditions classified elsewhere
0.713 0.287 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.713 0.287 0.000
I78.1 Naevus, nonneoplastic
0.712 0.288 0.000
M21.1 Varus deformity, not elsewhere classified
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.710 0.290 0.000
T45.0 Antiallergic and antiemetic drugs
0.710 0.290 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.709 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.708 0.292 0.000
R25.2 Cramp and spasm
0.707 0.293 0.000
M24.54 Contracture of joint (Hand)
0.707 0.293 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.706 0.294 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.704 0.295 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.295 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.704 0.295 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.704 0.295 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.704 0.295 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.704 0.296 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.704 0.296 0.000
Q35-Q37 Cleft lip and cleft palate
0.704 0.296 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.704 0.296 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.704 0.296 0.000
M00-M03 Infectious arthropathies
0.703 0.297 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.702 0.298 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.702 0.298 0.000
M07 Psoriatic and enteropathic arthropathies
0.702 0.298 0.000
J18 Pneumonia, organism unspecified
0.700 0.300 0.000
M81.98 Osteoporosis, unspecified (Other)
0.700 0.300 0.000
J81 Pulmonary oedema
0.699 0.301 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.697 0.303 0.000
J94.2 Haemothorax
0.697 0.303 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.697 0.303 0.000
S19 Other and unspecified injuries of neck
0.696 0.304 0.000
T25 Burn and corrosion of ankle and foot
0.696 0.304 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.696 0.304 0.000
S81.8 Open wound of other parts of lower leg
0.695 0.305 0.000
R41.0 Disorientation, unspecified
0.694 0.306 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.694 0.306 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.692 0.308 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.692 0.308 0.000
T23.2 Burn of second degree of wrist and hand
0.691 0.309 0.000
I77.5 Necrosis of artery
0.690 0.310 0.000
I77.4 Coeliac artery compression syndrome
0.690 0.310 0.000
I77.3 Arterial fibromuscular dysplasia
0.690 0.310 0.000
I77.2 Rupture of artery
0.690 0.310 0.000
R25.1 Tremor, unspecified
0.690 0.310 0.000
Q43.0 Meckel's diverticulum
0.689 0.311 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.689 0.311 0.000
G90-G99 Other disorders of the nervous system
0.689 0.311 0.000
M40 Kyphosis and lordosis
0.688 0.312 0.000
M43.1 Spondylolisthesis
0.688 0.312 0.000
I05.2 Mitral stenosis with insufficiency
0.687 0.313 0.000
J17 Pneumonia in diseases classified elsewhere
0.686 0.314 0.000
M12 Other specific arthropathies
0.685 0.314 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.685 0.314 0.000
M08 Juvenile arthritis
0.685 0.314 0.000
Q45 Other congenital malformations of digestive system
0.684 0.316 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.684 0.316 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.684 0.316 0.000
Q40 Other congenital malformations of upper alimentary tract
0.684 0.316 0.000
Q39 Congenital malformations of oesophagus
0.684 0.316 0.000
M82 Osteoporosis in diseases classified elsewhere
0.683 0.317 0.000
M83 Adult osteomalacia
0.682 0.318 0.000
M89.9 Disorder of bone, unspecified
0.682 0.318 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.681 0.319 0.000
R44.1 Visual hallucinations
0.681 0.319 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.680 0.320 0.000
S82.8 Fractures of other parts of lower leg
0.680 0.320 0.000
U51 Admission status on psychiatric patients
0.678 0.321 0.000
J96 Respiratory failure, not elsewhere classified
0.678 0.322 0.000
S80.8 Other superficial injuries of lower leg
0.678 0.322 0.000
S88 Traumatic amputation of lower leg
0.678 0.322 0.000
S87 Crushing injury of lower leg
0.678 0.322 0.000
S85 Injury of blood vessels at lower leg level
0.678 0.322 0.000
S84 Injury of nerves at lower leg level
0.678 0.322 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.677 0.323 0.000
S89 Other and unspecified injuries of lower leg
0.675 0.325 0.000
I62 Other nontraumatic intracranial haemorrhage
0.675 0.325 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.674 0.326 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.674 0.326 0.000
I72 Other aneurysm
0.674 0.326 0.000
M34 Systemic sclerosis
0.674 0.326 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.674 0.326 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.673 0.327 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.672 0.327 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.672 0.327 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.672 0.328 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.671 0.329 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.669 0.331 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.669 0.331 0.000
I27.2 Other secondary pulmonary hypertension
0.669 0.331 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.667 0.333 0.000
J21 Acute bronchiolitis
0.667 0.333 0.000
M10.4 Other secondary gout
0.666 0.333 0.000
M10.3 Gout due to impairment of renal function
0.666 0.333 0.000
M10.2 Drug-induced gout
0.666 0.333 0.000
M10.1 Lead-induced gout
0.666 0.333 0.000
M10.0 Idiopathic gout
0.666 0.333 0.000
T23.3 Burn of third degree of wrist and hand
0.666 0.334 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.665 0.335 0.000
I09 Other rheumatic heart diseases
0.663 0.336 0.000
I06 Rheumatic aortic valve diseases
0.663 0.336 0.000
Q00-Q07 Congenital malformations of the nervous system
0.663 0.337 0.000
J98 Other respiratory disorders
0.663 0.337 0.000
I71.0 Dissection of aorta [any part]
0.661 0.339 0.000
M20.3 Other deformity of hallux (acquired)
0.660 0.340 0.000
S82.3 Fracture of lower end of tibia
0.660 0.340 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.658 0.341 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.658 0.342 0.000
Q65 Congenital deformities of hip
0.657 0.343 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.657 0.343 0.000
M90 Osteopathies in diseases classified elsewhere
0.656 0.344 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.655 0.345 0.000
T39.4 Antirheumatics, not elsewhere classified
0.655 0.345 0.000
T39.2 Pyrazolone derivatives
0.655 0.345 0.000
W00-W19 Falls
0.655 0.345 0.000
M89.3 Hypertrophy of bone
0.654 0.346 0.000
M89.0 Algoneurodystrophy
0.654 0.346 0.000
S36 Injury of intra-abdominal organs
0.654 0.346 0.000
M10.98 Gout, unspecified (Other)
0.653 0.347 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.653 0.347 0.000
M10.94 Gout, unspecified (Hand)
0.653 0.347 0.000
M10.93 Gout, unspecified (Forearm)
0.653 0.347 0.000
M10.92 Gout, unspecified (Upper arm)
0.653 0.347 0.000
M10.91 Gout, unspecified (Shoulder region)
0.653 0.347 0.000
J84 Other interstitial pulmonary diseases
0.653 0.347 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.652 0.348 0.000
M21.2 Flexion deformity
0.652 0.348 0.000
M11 Other crystal arthropathies
0.652 0.348 0.000
J20 Acute bronchitis
0.651 0.348 0.000
M25 Other joint disorders, not elsewhere classified
0.651 0.349 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.650 0.350 0.000
M24.02 Loose body in joint (Upper arm)
0.649 0.351 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.648 0.352 0.000
J10.0 Influenza with pneumonia, influenza virus identified
0.647 0.353 0.000
J93.0 Spontaneous tension pneumothorax
0.647 0.353 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.646 0.354 0.000
J12 Viral pneumonia, not elsewhere classified
0.646 0.354 0.000
J09 Influenza due to certain identified influenza virus
0.646 0.354 0.000
Q50-Q56 Congenital malformations of genital organs
0.646 0.354 0.000
S11 Open wound of neck
0.646 0.354 0.000
I60.8 Other subarachnoid haemorrhage
0.645 0.355 0.000
Q61 Cystic kidney disease
0.645 0.355 0.000
B44.1 Other pulmonary aspergillosis
0.645 0.355 0.000
I08 Multiple valve diseases
0.644 0.356 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.644 0.356 0.000
I47 Paroxysmal tachycardia
0.643 0.357 0.000
I45 Other conduction disorders
0.643 0.357 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.643 0.357 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.642 0.358 0.000
S90-S99 Injuries to the ankle and foot
0.642 0.358 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.641 0.359 0.000
B44.9 Aspergillosis, unspecified
0.640 0.360 0.000
T45.5 Anticoagulants
0.640 0.360 0.000
T87.3 Neuroma of amputation stump
0.639 0.361 0.000
T21.3 Burn of third degree of trunk
0.638 0.362 0.000
Q85 Phakomatoses, not elsewhere classified
0.638 0.362 0.000
S27.0 Traumatic pneumothorax
0.636 0.364 0.000
I27.8 Other specified pulmonary heart diseases
0.636 0.364 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.636 0.364 0.000
Q38.8 Other congenital malformations of pharynx
0.635 0.365 0.000
Q38.6 Other congenital malformations of mouth
0.635 0.365 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.635 0.365 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.635 0.365 0.000
Q38.3 Other congenital malformations of tongue
0.635 0.365 0.000
Q38.2 Macroglossia
0.635 0.365 0.000
Q38.1 Ankyloglossia
0.635 0.365 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.635 0.365 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.634 0.366 0.000
S32 Fracture of lumbar spine and pelvis
0.633 0.367 0.000
M25.4 Effusion of joint
0.633 0.367 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.632 0.368 0.000
S20 Superficial injury of thorax
0.632 0.368 0.000
S21 Open wound of thorax
0.632 0.368 0.000
J94.9 Pleural condition, unspecified
0.631 0.369 0.000
J94.1 Fibrothorax
0.631 0.369 0.000
J94.0 Chylous effusion
0.631 0.369 0.000
M84.0 Malunion of fracture
0.631 0.369 0.000
I74 Arterial embolism and thrombosis
0.629 0.371 0.000
S17 Crushing injury of neck
0.629 0.371 0.000
S15 Injury of blood vessels at neck level
0.629 0.371 0.000
S18 Traumatic amputation at neck level
0.629 0.371 0.000
S16 Injury of muscle and tendon at neck level
0.629 0.371 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.629 0.371 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.629 0.371 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.628 0.371 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.628 0.371 0.000
I97.1 Other functional disturbances following cardiac surgery
0.628 0.372 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.628 0.372 0.000
S86.8 Injury of other muscles and tendons at lower leg level
0.628 0.372 0.000
H90-H95 Other disorders of ear
0.628 0.372 0.000
I78.9 Disease of capillaries, unspecified
0.627 0.373 0.000
M24.03 Loose body in joint (Forearm)
0.627 0.373 0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot
0.627 0.373 0.000
M88 Paget's disease of bone [osteitis deformans]
0.627 0.373 0.000
T86 Failure and rejection of transplanted organs and tissues
0.626 0.373 0.000
I65.2 Occlusion and stenosis of carotid artery
0.626 0.374 0.000
M24.9 Joint derangement, unspecified
0.625 0.374 0.000
M24.7 Protrusio acetabuli
0.625 0.374 0.000
M24.6 Ankylosis of joint
0.625 0.374 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.625 0.375 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.624 0.376 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.623 0.376 0.000
W19 Unspecified fall
0.624 0.376 0.000
S81.7 Multiple open wounds of lower leg
0.623 0.377 0.000
S80.0 Contusion of knee
0.623 0.377 0.000
I70.9 Generalised and unspecified atherosclerosis
0.621 0.378 0.000
I70.8 Atherosclerosis of other arteries
0.621 0.378 0.000
I70.1 Atherosclerosis of renal artery
0.621 0.378 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.621 0.379 0.000
T31 Burns classified according to extent of body surface involved
0.620 0.380 0.000
J00-J06 Acute upper respiratory infections
0.620 0.380 0.000
T23.7 Corrosion of third degree of wrist and hand
0.619 0.381 0.000
T23.6 Corrosion of second degree of wrist and hand
0.619 0.381 0.000
T23.5 Corrosion of first degree of wrist and hand
0.619 0.381 0.000
T23.4 Corrosion of unspecified degree of wrist and hand
0.619 0.381 0.000
T23.1 Burn of first degree of wrist and hand
0.619 0.381 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.617 0.383 0.000
M30.0 Polyarteritis nodosa
0.617 0.383 0.000
M42 Spinal osteochondrosis
0.616 0.383 0.000
S12.1 Fracture of second cervical vertebra
0.616 0.383 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.616 0.384 0.000
Q66 Congenital deformities of feet
0.615 0.385 0.000
I50 Heart failure
0.615 0.385 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.615 0.385 0.000
I47.1 Supraventricular tachycardia
0.614 0.386 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.613 0.387 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.613 0.387 0.000
T20.1 Burn of first degree of head and neck
0.612 0.387 0.000
I05.0 Mitral stenosis
0.612 0.388 0.000
I77.0 Arteriovenous fistula, acquired
0.612 0.388 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.611 0.389 0.000
M86 Osteomyelitis
0.611 0.389 0.000
B36 Other superficial mycoses
0.610 0.390 0.000
M20.0 Deformity of finger(s)
0.610 0.390 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.610 0.390 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.610 0.390 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.610 0.390 0.000
M31.9 Necrotising vasculopathy, unspecified
0.609 0.390 0.000
M31.8 Other specified necrotising vasculopathies
0.609 0.390 0.000
M31.7 Microscopic polyangiitis
0.609 0.390 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.609 0.390 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.609 0.390 0.000
M31.2 Lethal midline granuloma
0.609 0.390 0.000
M31.1 Thrombotic microangiopathy
0.609 0.390 0.000
M31.0 Hypersensitivity angiitis
0.609 0.390 0.000
Q89 Other congenital malformations, not elsewhere classified
0.609 0.391 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.608 0.391 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.608 0.391 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.608 0.391 0.000
T82.1 Mechanical complication of cardiac electronic device
0.607 0.393 0.000
T50.8 Diagnostic agents
0.607 0.393 0.000
T50.7 Analeptics and opioid receptor antagonists
0.607 0.393 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.607 0.393 0.000
T50.5 Appetite depressants
0.607 0.393 0.000
T50.4 Drugs affecting uric acid metabolism
0.607 0.393 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.607 0.393 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.607 0.393 0.000
T50.1 Loop [high-ceiling] diuretics
0.607 0.393 0.000
T50.0 Mineralocorticoids and their antagonists
0.607 0.393 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.607 0.393 0.000
S10 Superficial injury of neck
0.607 0.393 0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand
0.607 0.393 0.000
Q82 Other congenital malformations of skin
0.607 0.393 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.606 0.394 0.000
T45.8 Other primarily systemic and haematological agents
0.606 0.394 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.606 0.394 0.000
T45.6 Fibrinolysis-affecting drugs
0.606 0.394 0.000
T45.4 Iron and its compounds
0.606 0.394 0.000
T45.3 Enzymes, not elsewhere classified
0.606 0.394 0.000
T45.2 Vitamins, not elsewhere classified
0.606 0.394 0.000
S14 Injury of nerves and spinal cord at neck level
0.604 0.396 0.000
I42 Cardiomyopathy
0.604 0.396 0.000
J95.8 Other postprocedural respiratory disorders
0.604 0.396 0.000
M81.4 Drug-induced osteoporosis
0.603 0.397 0.000
T36.9 Systemic antibiotic, unspecified
0.603 0.397 0.000
T36.8 Other systemic antibiotics
0.603 0.397 0.000
T36.7 Antifungal antibiotics, systemically used
0.603 0.397 0.000
T36.6 Rifamycins
0.603 0.397 0.000
T36.5 Aminoglycosides
0.603 0.397 0.000
T36.4 Tetracyclines
0.603 0.397 0.000
T36.3 Macrolides
0.603 0.397 0.000
T36.2 Chloramphenicol group
0.603 0.397 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.603 0.397 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.603 0.397 0.000
M22 Disorders of patella
0.603 0.397 0.000
U51.0 Not Previously admitted to a psyciatric hospital
0.603 0.397 0.000
M06.3 Rheumatoid nodule
0.602 0.398 0.000
M81.8 Other osteoporosis
0.602 0.398 0.000
M81.6 Localised osteoporosis [Lequesne]
0.602 0.398 0.000
M81.5 Idiopathic osteoporosis
0.602 0.398 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.602 0.398 0.000
M81.1 Postoophorectomy osteoporosis
0.602 0.398 0.000
M81.0 Postmenopausal osteoporosis
0.602 0.398 0.000
J14 Pneumonia due to Haemophilus influenzae
0.602 0.398 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.602 0.398 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.601 0.399 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.601 0.399 0.000
R41.3 Other amnesia
0.601 0.399 0.000
M66 Spontaneous rupture of synovium and tendon
0.600 0.399 0.000
T21.7 Corrosion of third degree of trunk
0.600 0.400 0.000
T21.6 Corrosion of second degree of trunk
0.600 0.400 0.000
T21.5 Corrosion of first degree of trunk
0.600 0.400 0.000
T21.4 Corrosion of unspecified degree of trunk
0.600 0.400 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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