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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117802660
log Bayes Factor = 15.852
Chromosome 21   position 27,198,954  (GRCh37) Explore rs117802660 on Ensembl!
Variant rs117802660 is part of Cluster X0167

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
1.000 0.000 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z92 Personal history of medical treatment
1.000 0.000 0.000
Z92.3 Personal history of irradiation
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
M50-M54 Other dorsopathies
0.995 0.005 0.000
C15-C26 Malignant neoplasms of digestive organs
0.994 0.006 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.992 0.008 0.000
Z98 Other postsurgical states
0.991 0.009 0.000
A30-A49 Other bacterial diseases
0.990 0.010 0.000
M54 Dorsalgia
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
C18 Malignant neoplasm of colon
0.984 0.016 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.982 0.018 0.000
C79 Secondary malignant neoplasm of other sites
0.981 0.019 0.000
Z88.5 Personal history of allergy to narcotic agent
0.975 0.025 0.000
M45-M49 Spondylopathies
0.973 0.027 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.971 0.029 0.000
M20-M25 Other joint disorders
0.967 0.033 0.000
C50-C50 Malignant neoplasm of breast
0.966 0.034 0.000
A41 Other septicaemia
0.966 0.034 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.966 0.034 0.000
M54.1 Radiculopathy
0.960 0.040 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.959 0.041 0.000
M24 Other specific joint derangements
0.959 0.041 0.000
Z98.1 Arthrodesis status
0.954 0.046 0.000
Chapter VIII Diseases of the ear and mastoid process
0.953 0.047 0.000
M54.9 Dorsalgia, unspecified
0.953 0.047 0.000
M05-M14 Inflammatory polyarthropathies
0.952 0.048 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.951 0.049 0.000
D00-D09 In situ neoplasms
0.947 0.053 0.000
C50 Malignant neoplasm of breast
0.942 0.058 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.930 0.070 0.000
M10 Gout
0.927 0.073 0.000
M24.1 Other articular cartilage disorders
0.926 0.074 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.926 0.074 0.000
C50.9 Breast, unspecified
0.923 0.077 0.000
Y43 Primarily systemic agents
0.918 0.082 0.000
A49 Bacterial infection of unspecified site
0.913 0.087 0.000
M10.9 Gout, unspecified
0.910 0.090 0.000
C77.1 Intrathoracic lymph nodes
0.910 0.090 0.000
Z85 Personal history of malignant neoplasm
0.909 0.091 0.000
C18.9 Colon, unspecified
0.907 0.093 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.906 0.094 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.905 0.095 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.904 0.096 0.000
Z80 Family history of malignant neoplasm
0.902 0.098 0.000
M10.99 Gout, unspecified (Site unspecified)
0.901 0.099 0.000
C78.0 Secondary malignant neoplasm of lung
0.901 0.099 0.000
Z98.0 Intestinal bypass and anastomosis status
0.900 0.100 0.000
C18.5 Splenic flexure
0.900 0.100 0.000
M54.12 Radiculopathy (Cervical region)
0.894 0.106 0.000
C78.2 Secondary malignant neoplasm of pleura
0.893 0.107 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.893 0.107 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.891 0.109 0.000
M48 Other spondylopathies
0.890 0.110 0.000
Z83 Family history of other specific disorders
0.889 0.111 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.886 0.114 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.885 0.115 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.885 0.115 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.881 0.119 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.879 0.121 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.877 0.123 0.000
Z60 Problems related to social environment
0.875 0.125 0.000
Z88.2 Personal history of allergy to sulphonamides
0.872 0.128 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.870 0.130 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.869 0.131 0.000
Z63 Other problems related to primary support group, including family circumstances
0.868 0.132 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.868 0.132 0.000
Y43.3 Other antineoplastic drugs
0.868 0.132 0.000
M47 Spondylosis
0.864 0.136 0.000
C64-C68 Malignant neoplasms of urinary tract
0.863 0.137 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.863 0.137 0.000
C77.3 Axillary and upper limb lymph nodes
0.857 0.143 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.856 0.144 0.000
M23 Internal derangement of knee
0.855 0.145 0.000
D06 Carcinoma in situ of cervix uteri
0.853 0.147 0.000
C78.7 Secondary malignant neoplasm of liver
0.852 0.148 0.000
H90-H95 Other disorders of ear
0.847 0.153 0.000
M54.16 Radiculopathy (Lumbar region)
0.846 0.154 0.000
Y52 Agents primarily affecting the cardiovascular system
0.844 0.156 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.842 0.158 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.839 0.161 0.000
A41.9 Septicaemia, unspecified
0.837 0.163 0.000
M47.8 Other spondylosis
0.836 0.164 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.835 0.165 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.835 0.165 0.000
M48.0 Spinal stenosis
0.831 0.169 0.000
C18.6 Descending colon
0.831 0.169 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.830 0.170 0.000
M54.6 Pain in thoracic spine
0.830 0.170 0.000
B35-B49 Mycoses
0.829 0.171 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.826 0.174 0.000
Y57 Other and unspecified drugs and medicaments
0.824 0.176 0.000
Chapter V Mental and behavioural disorders
0.821 0.179 0.000
S90-S99 Injuries to the ankle and foot
0.820 0.180 0.000
Z84 Family history of other conditions
0.817 0.183 0.000
Z80.3 Family history of malignant neoplasm of breast
0.816 0.184 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.814 0.186 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.813 0.187 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.813 0.187 0.000
Z60.2 Living alone
0.811 0.189 0.000
C18.0 Caecum
0.810 0.190 0.000
Z83.7 Family history of diseases of the digestive system
0.809 0.191 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.804 0.196 0.000
M48.02 Spinal stenosis (Cervical region)
0.802 0.198 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.802 0.198 0.000
C77.8 Lymph nodes of multiple regions
0.801 0.199 0.000
C50.1 Central portion of breast
0.800 0.200 0.000
H80-H83 Diseases of inner ear
0.800 0.200 0.000
S40-S49 Injuries to the shoulder and upper arm
0.800 0.200 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.799 0.201 0.000
A49.8 Other bacterial infections of unspecified site
0.798 0.202 0.000
Q21 Congenital malformations of cardiac septa
0.798 0.202 0.000
M50 Cervical disk disorders
0.797 0.203 0.000
M24.0 Loose body in joint
0.795 0.205 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.794 0.206 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.791 0.209 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.789 0.211 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.788 0.212 0.000
C34 Malignant neoplasm of bronchus and lung
0.787 0.213 0.000
M45 Ankylosing spondylitis
0.786 0.214 0.000
D06.9 Cervix, unspecified
0.786 0.214 0.000
C18.2 Ascending colon
0.786 0.214 0.000
Q50-Q56 Congenital malformations of genital organs
0.785 0.215 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.785 0.215 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.784 0.216 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.781 0.219 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.781 0.219 0.000
S70-S79 Injuries to the hip and thigh
0.780 0.220 0.000
H65-H75 Diseases of middle ear and mastoid
0.779 0.221 0.000
C18.3 Hepatic flexure
0.778 0.222 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.777 0.223 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.777 0.223 0.000
C50.2 Upper-inner quadrant of breast
0.776 0.224 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.776 0.224 0.000
B95-B98 Bacterial, viral and other infectious agents
0.776 0.224 0.000
V10-V19 Pedal cyclist injured in transport accident
0.775 0.225 0.000
M25 Other joint disorders, not elsewhere classified
0.774 0.226 0.000
B99-B99 Other infectious diseases
0.774 0.226 0.000
V40-V49 Car occupant injured in transport accident
0.771 0.229 0.000
C77.9 Lymph node, unspecified
0.770 0.230 0.000
A41.8 Other specified septicaemia
0.769 0.231 0.000
Chapter XXII Codes for special purposes
0.767 0.233 0.000
M11 Other crystal arthropathies
0.765 0.235 0.000
M40-M43 Deforming dorsopathies
0.765 0.235 0.000
Z98.8 Other specified postsurgical states
0.765 0.235 0.000
D03 Melanoma in situ
0.764 0.236 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.764 0.236 0.000
C18.1 Appendix
0.762 0.238 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.762 0.238 0.000
D05 Carcinoma in situ of breast
0.762 0.238 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.761 0.239 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.760 0.240 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.758 0.242 0.000
Y44 Agents primarily affecting blood constituents
0.758 0.242 0.000
Z57 Occupational exposure to risk-factors
0.756 0.244 0.000
S00-S09 Injuries to the head
0.755 0.245 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.754 0.246 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.754 0.246 0.000
M47.86 Other spondylosis (Lumbar region)
0.753 0.247 0.000
A46 Erysipelas
0.753 0.247 0.000
F22 Persistent delusional disorders
0.752 0.247 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.751 0.249 0.000
Z29 Need for other prophylactic measures
0.751 0.249 0.000
M53 Other dorsopathies, not elsewhere classified
0.751 0.249 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.751 0.249 0.000
Z63.4 Disappearance and death of family member
0.750 0.250 0.000
E10-E14 Diabetes mellitus
0.748 0.252 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.746 0.254 0.000
M91-M94 Chondropathies
0.744 0.256 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.743 0.257 0.000
C79.2 Secondary malignant neoplasm of skin
0.741 0.259 0.000
Q80-Q89 Other congenital malformations
0.740 0.260 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.738 0.261 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.738 0.262 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.738 0.262 0.000
M51 Other intervertebral disk disorders
0.738 0.262 0.000
B25-B34 Other viral diseases
0.738 0.262 0.000
M46 Other inflammatory spondylopathies
0.737 0.263 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.736 0.264 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.736 0.264 0.000
A49.0 Staphylococcal infection, unspecified
0.736 0.264 0.000
M24.2 Disorder of ligament
0.736 0.264 0.000
Q21.1 Atrial septal defect
0.735 0.265 0.000
B00 Herpesviral [herpes simplex] infections
0.735 0.265 0.000
B15-B19 Viral hepatitis
0.733 0.267 0.000
S91 Open wound of ankle and foot
0.732 0.268 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.731 0.268 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.731 0.269 0.000
F22.0 Delusional disorder
0.730 0.270 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.727 0.273 0.000
Q27 Other congenital malformations of peripheral vascular system
0.726 0.274 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.725 0.275 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.722 0.278 0.000
E10 Insulin-dependent diabetes mellitus
0.722 0.278 0.000
Z83.3 Family history of diabetes mellitus
0.722 0.278 0.000
X50-X57 Overexertion, travel and privation
0.722 0.278 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.721 0.279 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.721 0.279 0.000
O80-O84 Delivery
0.721 0.279 0.000
H60-H62 Diseases of external ear
0.720 0.280 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.720 0.280 0.000
Z92.8 Personal history of other medical treatment
0.719 0.281 0.000
E20-E35 Disorders of other endocrine glands
0.719 0.281 0.000
Z22 Carrier of infectious disease
0.718 0.282 0.000
C79.6 Secondary malignant neoplasm of ovary
0.718 0.282 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.717 0.283 0.000
Z92.5 Personal history of rehabilitation measures
0.717 0.283 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.716 0.284 0.000
M23.5 Chronic instability of knee
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
V20-V29 Motorcycle rider injured in transport accident
0.715 0.285 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.715 0.285 0.000
M50.2 Other cervical disk displacement
0.714 0.286 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.713 0.287 0.000
C21 Malignant neoplasm of anus and anal canal
0.712 0.287 0.000
C17 Malignant neoplasm of small intestine
0.712 0.287 0.000
C23 Malignant neoplasm of gallbladder
0.712 0.287 0.000
D04 Carcinoma in situ of skin
0.712 0.288 0.000
A49.9 Bacterial infection, unspecified
0.712 0.288 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.711 0.288 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.711 0.288 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.711 0.288 0.000
H93 Other disorders of ear, not elsewhere classified
0.711 0.289 0.000
M34 Systemic sclerosis
0.711 0.289 0.000
Y95 Nosocomial condition
0.710 0.290 0.000
A48 Other bacterial diseases, not elsewhere classified
0.710 0.290 0.000
A44 Bartonellosis
0.710 0.290 0.000
A43 Nocardiosis
0.710 0.290 0.000
A42 Actinomycosis
0.710 0.290 0.000
A40 Streptococcal septicaemia
0.710 0.290 0.000
A39 Meningococcal infection
0.710 0.290 0.000
A37 Whooping cough
0.710 0.290 0.000
A36 Diphtheria
0.710 0.290 0.000
A32 Listeriosis
0.710 0.290 0.000
A31 Infection due to other mycobacteria
0.710 0.290 0.000
A30 Leprosy [Hansen's disease]
0.710 0.290 0.000
A38 Scarlet fever
0.710 0.290 0.000
A35 Other tetanus
0.710 0.290 0.000
A34 Obstetrical tetanus
0.710 0.290 0.000
A33 Tetanus neonatorum
0.710 0.290 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.709 0.291 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.709 0.291 0.000
M54.8 Other dorsalgia
0.709 0.291 0.000
M54.0 Panniculitis affecting regions of neck and back
0.709 0.291 0.000
M54.2 Cervicalgia
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.708 0.292 0.000
M54.3 Sciatica
0.707 0.293 0.000
Y40 Systemic antibiotics
0.706 0.293 0.000
C77.0 Lymph nodes of head, face and neck
0.706 0.293 0.000
C34.1 Upper lobe, bronchus or lung
0.706 0.294 0.000
B02 Zoster [herpes zoster]
0.706 0.294 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.706 0.294 0.000
C18.8 Overlapping lesion of colon
0.705 0.295 0.000
M54.4 Lumbago with sciatica
0.705 0.295 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.705 0.295 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.704 0.296 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.704 0.296 0.000
Y59 Other and unspecified vaccines and biological substances
0.704 0.296 0.000
Y58 Bacterial vaccines
0.704 0.296 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.704 0.296 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.296 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.704 0.296 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.704 0.296 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
Y48 Anaesthetics and therapeutic gases
0.704 0.296 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.704 0.296 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.704 0.296 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.704 0.296 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.704 0.296 0.000
Z89 Acquired absence of limb
0.703 0.297 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.702 0.298 0.000
S40 Superficial injury of shoulder and upper arm
0.701 0.298 0.000
M13 Other arthritis
0.701 0.299 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.701 0.299 0.000
S72 Fracture of femur
0.700 0.300 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.700 0.300 0.000
M22 Disorders of patella
0.700 0.300 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.699 0.301 0.000
M65-M68 Disorders of synovium and tendon
0.698 0.302 0.000
M49 Spondylopathies in diseases classified elsewhere
0.698 0.302 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.697 0.303 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.697 0.303 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.696 0.304 0.000
M48.09 Spinal stenosis (Site unspecified)
0.694 0.306 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.693 0.307 0.000
M33 Dermatopolymyositis
0.693 0.307 0.000
M32 Systemic lupus erythematosus
0.693 0.307 0.000
M30 Polyarteritis nodosa and related conditions
0.693 0.307 0.000
A41.4 Septicaemia due to anaerobes
0.692 0.308 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.692 0.308 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.692 0.308 0.000
Z65 Problems related to other psychosocial circumstances
0.692 0.308 0.000
Z64 Problems related to certain psychosocial circumstances
0.692 0.308 0.000
Z62 Other problems related to upbringing
0.692 0.308 0.000
Z61 Problems related to negative life events in childhood
0.692 0.308 0.000
Z59 Problems related to housing and economic circumstances
0.692 0.308 0.000
Z58 Problems related to physical environment
0.692 0.308 0.000
Z56 Problems related to employment and unemployment
0.692 0.308 0.000
Z55 Problems related to education and literacy
0.692 0.308 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.691 0.308 0.000
C67 Malignant neoplasm of bladder
0.691 0.309 0.000
C71 Malignant neoplasm of brain
0.691 0.309 0.000
H83 Other diseases of inner ear
0.691 0.309 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.689 0.311 0.000
M54.19 Radiculopathy (Site unspecified)
0.688 0.312 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.688 0.312 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.688 0.312 0.000
M54.14 Radiculopathy (Thoracic region)
0.688 0.312 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.688 0.312 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.688 0.312 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.688 0.312 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.687 0.312 0.000
Q35-Q37 Cleft lip and cleft palate
0.687 0.312 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.687 0.312 0.000
M24.9 Joint derangement, unspecified
0.687 0.313 0.000
M24.7 Protrusio acetabuli
0.687 0.313 0.000
M24.6 Ankylosis of joint
0.687 0.313 0.000
M24.5 Contracture of joint
0.687 0.313 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.687 0.313 0.000
Z84.8 Family history of other specified conditions
0.686 0.314 0.000
Y42.7 Androgens and anabolic congeners
0.685 0.315 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.685 0.315 0.000
Q28 Other congenital malformations of circulatory system
0.685 0.315 0.000
Z63.0 Problems in relationship with spouse or partner
0.685 0.315 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.685 0.315 0.000
Y43.4 Immunosuppressive agents
0.684 0.316 0.000
A80-A89 Viral infections of the central nervous system
0.683 0.316 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.683 0.317 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.683 0.317 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.683 0.317 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.683 0.317 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.683 0.317 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.683 0.317 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.683 0.317 0.000
M14 Arthropathies in other diseases classified elsewhere
0.682 0.317 0.000
M12 Other specific arthropathies
0.682 0.317 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.682 0.317 0.000
M08 Juvenile arthritis
0.682 0.317 0.000
A49.1 Streptococcal infection, unspecified
0.682 0.318 0.000
Z93 Artificial opening status
0.682 0.318 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.681 0.319 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.681 0.319 0.000
Y57.8 Other drugs and medicaments
0.680 0.320 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.679 0.321 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.679 0.321 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.679 0.321 0.000
Y42.5 Other oestrogens and progestogens
0.679 0.321 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.678 0.322 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.678 0.322 0.000
C50.6 Axillary tail of breast
0.675 0.324 0.000
X60-X84 Intentional self-harm
0.675 0.325 0.000
Q60-Q64 Congenital malformations of the urinary system
0.675 0.325 0.000
Z63.8 Other specified problems related to primary support group
0.674 0.326 0.000
B37 Candidiasis
0.674 0.326 0.000
H92 Otalgia and effusion of ear
0.674 0.326 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.672 0.328 0.000
O80 Single spontaneous delivery
0.671 0.329 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.669 0.331 0.000
D09 Carcinoma in situ of other and unspecified sites
0.669 0.331 0.000
Z92.0 Personal history of contraception
0.669 0.331 0.000
E10.9 Without complications
0.668 0.332 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.668 0.332 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.668 0.332 0.000
Z91.6 Personal history of other physical trauma
0.668 0.332 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.668 0.332 0.000
T33-T35 Frostbite
0.667 0.333 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.667 0.333 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.667 0.333 0.000
T00-T07 Injuries involving multiple body regions
0.667 0.333 0.000
S10-S19 Injuries to the neck
0.667 0.333 0.000
C77.5 Intrapelvic lymph nodes
0.666 0.333 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.666 0.334 0.000
A00-A09 Intestinal infectious diseases
0.666 0.334 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.665 0.334 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.666 0.334 0.000
C65 Malignant neoplasm of renal pelvis
0.665 0.335 0.000
M10.4 Other secondary gout
0.665 0.335 0.000
M10.3 Gout due to impairment of renal function
0.665 0.335 0.000
M10.2 Drug-induced gout
0.665 0.335 0.000
M10.1 Lead-induced gout
0.665 0.335 0.000
M10.0 Idiopathic gout
0.665 0.335 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.664 0.336 0.000
M24.18 Other articular cartilage disorders (Other)
0.664 0.336 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.664 0.336 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.664 0.336 0.000
M24.14 Other articular cartilage disorders (Hand)
0.664 0.336 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.664 0.336 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.664 0.336 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.663 0.337 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.661 0.339 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.661 0.339 0.000
S20-S29 Injuries to the thorax
0.660 0.340 0.000
T87 Complications peculiar to reattachment and amputation
0.660 0.340 0.000
C66 Malignant neoplasm of ureter
0.660 0.340 0.000
C50.5 Lower-outer quadrant of breast
0.659 0.341 0.000
Y43.9 Primarily systemic agent, unspecified
0.658 0.342 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.658 0.342 0.000
Y43.6 Enzymes, not elsewhere classified
0.658 0.342 0.000
Y43.5 Acidifying and alkalising agents
0.658 0.342 0.000
Y43.2 Antineoplastic natural products
0.658 0.342 0.000
Y43.1 Antineoplastic antimetabolites
0.658 0.342 0.000
Y43.0 Antiallergic and antiemetic drugs
0.658 0.342 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.658 0.342 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.656 0.344 0.000
A49.3 Mycoplasma infection, unspecified
0.655 0.345 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.655 0.345 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.654 0.346 0.000
Chapter VI Diseases of the nervous system
0.654 0.346 0.000
C18.7 Sigmoid colon
0.653 0.347 0.000
Y57.5 X-ray contrast media
0.653 0.347 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.653 0.347 0.000
C77.2 Intra-abdominal lymph nodes
0.653 0.347 0.000
M10.98 Gout, unspecified (Other)
0.652 0.347 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.652 0.347 0.000
M10.94 Gout, unspecified (Hand)
0.652 0.347 0.000
M10.93 Gout, unspecified (Forearm)
0.652 0.347 0.000
M10.92 Gout, unspecified (Upper arm)
0.652 0.347 0.000
M10.91 Gout, unspecified (Shoulder region)
0.652 0.347 0.000
M10.90 Gout, unspecified (Multiple sites)
0.652 0.347 0.000
Q00-Q07 Congenital malformations of the nervous system
0.652 0.348 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.652 0.348 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.652 0.348 0.000
S91.3 Open wound of other parts of foot
0.652 0.348 0.000
H80 Otosclerosis
0.651 0.349 0.000
C50.8 Overlapping lesion of breast
0.651 0.349 0.000
S42 Fracture of shoulder and upper arm
0.650 0.350 0.000
M47.89 Other spondylosis (Site unspecified)
0.650 0.350 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.649 0.351 0.000
D05.1 Intraductal carcinoma in situ
0.649 0.351 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.649 0.351 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.648 0.352 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.648 0.352 0.000
S00 Superficial injury of head
0.648 0.352 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.647 0.353 0.000
Z80.6 Family history of leukaemia
0.647 0.353 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.647 0.353 0.000
B44 Aspergillosis
0.647 0.353 0.000
C50.3 Lower-inner quadrant of breast
0.646 0.353 0.000
C24.0 Extrahepatic bile duct
0.645 0.355 0.000
C20 Malignant neoplasm of rectum
0.645 0.355 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.645 0.355 0.000
C69 Malignant neoplasm of eye and adnexa
0.643 0.357 0.000
M05 Seropositive rheumatoid arthritis
0.643 0.357 0.000
T86 Failure and rejection of transplanted organs and tissues
0.642 0.358 0.000
M86-M90 Other osteopathies
0.642 0.358 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.641 0.359 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.641 0.359 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.641 0.359 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.640 0.360 0.000
Z91.7 Personal history of female genital mutilation
0.640 0.360 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.640 0.360 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.640 0.360 0.000
Z91.2 Personal history of poor personal hygiene
0.640 0.360 0.000
M80-M85 Disorders of bone density and structure
0.640 0.360 0.000
M24.02 Loose body in joint (Upper arm)
0.639 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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