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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117813251
log Bayes Factor = 20.0984
Chromosome 17   position 74,197,931  (GRCh37) Explore rs117813251 on Ensembl!
Variant rs117813251 is part of Cluster X0019

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M45-M49 Spondylopathies
0.999 0.001 0.000
M47 Spondylosis
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.994 0.006 0.000
M47.8 Other spondylosis
0.993 0.007 0.000
Chapter VII Diseases of the eye and adnexa
0.993 0.007 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.992 0.008 0.000
M50-M54 Other dorsopathies
0.990 0.010 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.989 0.011 0.000
I84 Haemorrhoids
0.987 0.013 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.986 0.014 0.000
Chapter VI Diseases of the nervous system
0.985 0.015 0.000
Z13 Special screening examination for other diseases and disorders
0.985 0.015 0.000
M54 Dorsalgia
0.984 0.016 0.000
K50-K52 Noninfective enteritis and colitis
0.983 0.017 0.000
N81 Female genital prolapse
0.975 0.025 0.000
E10-E14 Diabetes mellitus
0.975 0.025 0.000
Chapter XX External causes of morbidity and mortality
0.972 0.028 0.000
Z13.9 Special screening examination, unspecified
0.971 0.029 0.000
K52 Other non-infective gastro-enteritis and colitis
0.971 0.029 0.000
B95-B98 Bacterial, viral and other infectious agents
0.968 0.032 0.000
M47.86 Other spondylosis (Lumbar region)
0.967 0.033 0.000
I84.1 Internal haemorrhoids with other complications
0.966 0.034 0.000
A30-A49 Other bacterial diseases
0.962 0.038 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.960 0.040 0.000
I30-I52 Other forms of heart disease
0.958 0.042 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.956 0.044 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.951 0.049 0.000
G40-G47 Episodic and paroxysmal disorders
0.945 0.055 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.942 0.058 0.000
H30-H36 Disorders of choroid and retina
0.942 0.058 0.000
Chapter V Mental and behavioural disorders
0.941 0.059 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.935 0.065 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.935 0.065 0.000
N80 Endometriosis
0.934 0.066 0.000
I34 Nonrheumatic mitral valve disorders
0.930 0.070 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.925 0.075 0.000
N30-N39 Other diseases of urinary system
0.925 0.075 0.000
I44 Atrioventricular and left bundle-branch block
0.924 0.076 0.000
M54.2 Cervicalgia
0.922 0.078 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.919 0.081 0.000
I84.6 Residual haemorrhoidal skin tags
0.917 0.083 0.000
N35 Urethral stricture
0.913 0.087 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.912 0.088 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.912 0.088 0.000
N81.6 Rectocele
0.910 0.090 0.000
H02 Other disorders of eyelid
0.909 0.091 0.000
Chapter X Diseases of the respiratory system
0.909 0.091 0.000
M47.2 Other spondylosis with radiculopathy
0.909 0.091 0.000
N35.9 Urethral stricture, unspecified
0.905 0.095 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.904 0.096 0.000
E11 Non-insulin-dependent diabetes mellitus
0.904 0.096 0.000
M54.5 Low back pain
0.903 0.097 0.000
K55-K64 Other diseases of intestines
0.901 0.099 0.000
D50-D53 Nutritional anaemias
0.900 0.100 0.000
K65-K67 Diseases of peritoneum
0.898 0.102 0.000
A41 Other septicaemia
0.897 0.103 0.000
H02.9 Disorder of eyelid, unspecified
0.895 0.105 0.000
E10 Insulin-dependent diabetes mellitus
0.894 0.106 0.000
M54.9 Dorsalgia, unspecified
0.890 0.110 0.000
I80 Phlebitis and thrombophlebitis
0.883 0.117 0.000
I34.0 Mitral (valve) insufficiency
0.882 0.118 0.000
M40-M43 Deforming dorsopathies
0.881 0.119 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.879 0.121 0.000
M54.22 Cervicalgia (Cervical region)
0.878 0.122 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.877 0.123 0.000
M48 Other spondylopathies
0.877 0.123 0.000
D50 Iron deficiency anaemia
0.876 0.124 0.000
A41.9 Septicaemia, unspecified
0.872 0.128 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.870 0.130 0.000
H04 Disorders of lachrymal system
0.869 0.131 0.000
H53-H54 Visual disturbances and blindness
0.868 0.132 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.867 0.133 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.866 0.134 0.000
A49 Bacterial infection of unspecified site
0.865 0.135 0.000
Chapter VIII Diseases of the ear and mastoid process
0.860 0.140 0.000
M47.82 Other spondylosis (Cervical region)
0.859 0.141 0.000
T86 Failure and rejection of transplanted organs and tissues
0.859 0.141 0.000
H35 Other retinal disorders
0.856 0.144 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.856 0.144 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.853 0.147 0.000
N10-N16 Renal tubulo-interstitial diseases
0.852 0.148 0.000
Z03.8 Observation for other suspected diseases and conditions
0.850 0.150 0.000
S40-S49 Injuries to the shoulder and upper arm
0.848 0.152 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.848 0.152 0.000
N81.5 Vaginal enterocele
0.847 0.153 0.000
M47.9 Spondylosis, unspecified
0.843 0.157 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.843 0.157 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.842 0.158 0.000
Y43 Primarily systemic agents
0.841 0.159 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.840 0.160 0.000
I84.9 Unspecified haemorrhoids without complication
0.839 0.161 0.000
S00-S09 Injuries to the head
0.839 0.161 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.839 0.161 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.837 0.163 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.834 0.166 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.834 0.166 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.833 0.167 0.000
N80.9 Endometriosis, unspecified
0.832 0.168 0.000
N80.0 Endometriosis of uterus
0.828 0.172 0.000
Z22 Carrier of infectious disease
0.828 0.172 0.000
J09-J18 Influenza and pneumonia
0.828 0.172 0.000
E14 Unspecified diabetes mellitus
0.826 0.174 0.000
E50-E64 Other nutritional deficiencies
0.825 0.175 0.000
I34.1 Mitral (valve) prolapse
0.823 0.177 0.000
N81.0 Female urethrocele
0.822 0.178 0.000
N81.2 Incomplete uterovaginal prolapse
0.822 0.178 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.821 0.179 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.820 0.180 0.000
N99-N99 Other disorders of the genitourinary system
0.819 0.181 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.819 0.181 0.000
T81 Complications of procedures, not elsewhere classified
0.819 0.181 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.819 0.181 0.000
T66-T78 Other and unspecified effects of external causes
0.818 0.182 0.000
K40-K46 Hernia
0.818 0.182 0.000
M47.89 Other spondylosis (Site unspecified)
0.817 0.183 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.817 0.183 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.815 0.185 0.000
K65 Peritonitis
0.815 0.185 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.815 0.185 0.000
K52.1 Toxic gastro-enteritis and colitis
0.814 0.186 0.000
N87 Dysplasia of cervix uteri
0.813 0.187 0.000
K62 Other diseases of anus and rectum
0.812 0.188 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.812 0.188 0.000
D50.9 Iron deficiency anaemia, unspecified
0.811 0.189 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.809 0.191 0.000
N00-N08 Glomerular diseases
0.809 0.191 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.807 0.193 0.000
E11.5 With peripheral circulatory complications
0.805 0.195 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.805 0.195 0.000
S80-S89 Injuries to the knee and lower leg
0.804 0.196 0.000
H53 Visual disturbances
0.800 0.200 0.000
I84.5 External haemorrhoids without complication
0.800 0.200 0.000
K50 Crohn's disease [regional enteritis]
0.799 0.201 0.000
M43 Other deforming dorsopathies
0.798 0.202 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.798 0.202 0.000
N20-N23 Urolithiasis
0.797 0.203 0.000
Chapter XXII Codes for special purposes
0.797 0.203 0.000
E65-E68 Obesity and other hyperalimentation
0.797 0.203 0.000
G90-G99 Other disorders of the nervous system
0.796 0.204 0.000
M54.59 Low back pain (Site unspecified)
0.796 0.204 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.796 0.204 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.796 0.204 0.000
N36 Other disorders of urethra
0.791 0.209 0.000
K60 Fissure and fistula of anal and rectal regions
0.791 0.209 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.791 0.209 0.000
D50.8 Other iron deficiency anaemias
0.790 0.210 0.000
M48.0 Spinal stenosis
0.790 0.210 0.000
E11.4 With neurological complications
0.790 0.210 0.000
M80-M85 Disorders of bone density and structure
0.790 0.210 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.789 0.211 0.000
F17.1 Harmful use
0.788 0.212 0.000
I44.7 Left bundle-branch block, unspecified
0.787 0.213 0.000
M46 Other inflammatory spondylopathies
0.786 0.214 0.000
S70-S79 Injuries to the hip and thigh
0.785 0.215 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.784 0.216 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.784 0.216 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.783 0.217 0.000
H36 Retinal disorders in diseases classified elsewhere
0.783 0.217 0.000
I44.2 Atrioventricular block, complete
0.782 0.218 0.000
I31 Other diseases of pericardium
0.781 0.219 0.000
I60-I69 Cerebrovascular diseases
0.781 0.219 0.000
J00-J06 Acute upper respiratory infections
0.781 0.219 0.000
I44.1 Atrioventricular block, second degree
0.780 0.220 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.778 0.222 0.000
E70-E90 Metabolic disorders
0.778 0.222 0.000
I87 Other disorders of veins
0.777 0.223 0.000
H55-H59 Other disorders of eye and adnexa
0.777 0.223 0.000
S01 Open wound of head
0.775 0.225 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.775 0.225 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.773 0.227 0.000
E10.3 With ophthalmic complications
0.773 0.227 0.000
B35-B49 Mycoses
0.773 0.227 0.000
K62.1 Rectal polyp
0.770 0.230 0.000
H35.3 Degeneration of macula and posterior pole
0.770 0.230 0.000
Z03.3 Observation for suspected nervous system disorder
0.770 0.230 0.000
I44.0 Atrioventricular block, first degree
0.769 0.231 0.000
H02.1 Ectropion of eyelid
0.769 0.231 0.000
F30-F39 Mood [affective] disorders
0.769 0.231 0.000
G58 Other mononeuropathies
0.769 0.231 0.000
M54.3 Sciatica
0.769 0.231 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.768 0.232 0.000
N80.8 Other endometriosis
0.767 0.233 0.000
M65-M68 Disorders of synovium and tendon
0.767 0.233 0.000
M51 Other intervertebral disk disorders
0.766 0.234 0.000
S50-S59 Injuries to the elbow and forearm
0.764 0.235 0.000
N81.3 Complete uterovaginal prolapse
0.764 0.236 0.000
Z22.3 Carrier of other specified bacterial diseases
0.763 0.237 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.762 0.237 0.000
N89 Other noninflammatory disorders of vagina
0.761 0.239 0.000
E10.9 Without complications
0.761 0.239 0.000
M60-M63 Disorders of muscles
0.760 0.240 0.000
I82 Other venous embolism and thrombosis
0.759 0.241 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.758 0.242 0.000
I45 Other conduction disorders
0.758 0.242 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.755 0.245 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.754 0.246 0.000
M86-M90 Other osteopathies
0.754 0.246 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.753 0.247 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.753 0.247 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.752 0.248 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.752 0.248 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.751 0.249 0.000
S90-S99 Injuries to the ankle and foot
0.751 0.249 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.750 0.250 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.750 0.250 0.000
K43 Ventral hernia
0.750 0.250 0.000
H33 Retinal detachments and breaks
0.747 0.253 0.000
T79-T79 Certain early complications of trauma
0.746 0.253 0.000
K55 Vascular disorders of intestine
0.744 0.256 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.744 0.256 0.000
G40 Epilepsy
0.742 0.258 0.000
Z00.0 General medical examination
0.741 0.259 0.000
I30 Acute pericarditis
0.741 0.259 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.740 0.260 0.000
G47 Sleep disorders
0.740 0.260 0.000
I38 Endocarditis, valve unspecified
0.739 0.261 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.739 0.261 0.000
Y42.5 Other oestrogens and progestogens
0.739 0.261 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.737 0.263 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.736 0.264 0.000
K65.0 Acute peritonitis
0.734 0.266 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.732 0.268 0.000
F60-F69 Disorders of adult personality and behaviour
0.731 0.269 0.000
N40-N51 Diseases of male genital organs
0.731 0.269 0.000
T93 Sequelae of injuries of lower limb
0.730 0.270 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.729 0.271 0.000
I84.0 Internal thrombosed haemorrhoids
0.729 0.271 0.000
K62.0 Anal polyp
0.729 0.271 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.729 0.271 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.728 0.272 0.000
M54.4 Lumbago with sciatica
0.727 0.273 0.000
I10-I15 Hypertensive diseases
0.727 0.273 0.000
N81.9 Female genital prolapse, unspecified
0.727 0.273 0.000
Z29 Need for other prophylactic measures
0.724 0.276 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.724 0.276 0.000
S20-S29 Injuries to the thorax
0.721 0.279 0.000
E11.2 With renal complications
0.721 0.279 0.000
D70 Agranulocytosis
0.721 0.279 0.000
A00-A09 Intestinal infectious diseases
0.720 0.279 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.720 0.280 0.000
H02.6 Xanthelasma of eyelid
0.720 0.280 0.000
G51 Facial nerve disorders
0.719 0.281 0.000
E11.6 With other specified complications
0.718 0.282 0.000
A49.0 Staphylococcal infection, unspecified
0.717 0.282 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.717 0.283 0.000
J10 Influenza due to identified influenza virus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
H90-H95 Other disorders of ear
0.717 0.283 0.000
J90-J94 Other diseases of pleura
0.717 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.716 0.284 0.000
M54.56 Low back pain (Lumbar region)
0.716 0.284 0.000
K35-K38 Diseases of appendix
0.716 0.284 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.716 0.284 0.000
I83 Varicose veins of lower extremities
0.716 0.284 0.000
M47.1 Other spondylosis with myelopathy
0.715 0.284 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.715 0.284 0.000
Z10 Routine general health check-up of defined subpopulation
0.715 0.285 0.000
M43.1 Spondylolisthesis
0.715 0.285 0.000
T87 Complications peculiar to reattachment and amputation
0.714 0.286 0.000
K30 Dyspepsia
0.714 0.286 0.000
N86 Erosion and ectropion of cervix uteri
0.714 0.286 0.000
S01.0 Open wound of scalp
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.713 0.286 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.713 0.287 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.713 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.287 0.000
B65-B83 Helminthiases
0.713 0.287 0.000
B50-B64 Protozoal diseases
0.713 0.287 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A80-A89 Viral infections of the central nervous system
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A65-A69 Other spirochaetal diseases
0.713 0.287 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
A15-A19 Tuberculosis
0.713 0.287 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.712 0.288 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.712 0.288 0.000
M47.84 Other spondylosis (Thoracic region)
0.712 0.288 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.712 0.288 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.712 0.288 0.000
T90 Sequelae of injuries of head
0.712 0.288 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.712 0.288 0.000
I84.3 External thrombosed haemorrhoids
0.712 0.288 0.000
E13 Other specified diabetes mellitus
0.712 0.288 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.712 0.288 0.000
I88 Nonspecific lymphadenitis
0.711 0.288 0.000
I86 Varicose veins of other sites
0.711 0.288 0.000
I81 Portal vein thrombosis
0.711 0.288 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.711 0.289 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.710 0.290 0.000
M53 Other dorsopathies, not elsewhere classified
0.710 0.290 0.000
E40-E46 Malnutrition
0.709 0.291 0.000
K31 Other diseases of stomach and duodenum
0.709 0.291 0.000
H02.5 Other disorders affecting eyelid function
0.709 0.291 0.000
T86.0 Bone-marrow transplant rejection
0.709 0.291 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.707 0.293 0.000
N98 Complications associated with artificial fertilisation
0.707 0.293 0.000
N91 Absent, scanty and rare menstruation
0.707 0.293 0.000
N82 Fistulae involving female genital tract
0.707 0.293 0.000
N96 Habitual aborter
0.707 0.293 0.000
G70-G73 Diseases of myoneural junction and muscle
0.706 0.294 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.706 0.294 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.706 0.294 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.706 0.294 0.000
Z13.5 Special screening examination for eye and ear disorders
0.706 0.294 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.706 0.294 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.706 0.294 0.000
Z13.2 Special screening examination for nutritional disorders
0.706 0.294 0.000
M54.8 Other dorsalgia
0.705 0.294 0.000
M54.6 Pain in thoracic spine
0.705 0.294 0.000
M54.0 Panniculitis affecting regions of neck and back
0.705 0.294 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.705 0.295 0.000
Y52 Agents primarily affecting the cardiovascular system
0.705 0.295 0.000
M54.57 Low back pain (Lumbosacral region)
0.704 0.296 0.000
Y40 Systemic antibiotics
0.704 0.296 0.000
Q80-Q89 Other congenital malformations
0.704 0.296 0.000
K61 Abscess of anal and rectal regions
0.702 0.297 0.000
V20-V29 Motorcycle rider injured in transport accident
0.702 0.298 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.702 0.298 0.000
N94.6 Dysmenorrhoea, unspecified
0.701 0.299 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.701 0.299 0.000
H10-H13 Disorders of conjunctiva
0.700 0.300 0.000
T86.1 Kidney transplant failure and rejection
0.700 0.300 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.700 0.300 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.699 0.301 0.000
I33 Acute and subacute endocarditis
0.699 0.301 0.000
A49.8 Other bacterial infections of unspecified site
0.699 0.301 0.000
N13 Obstructive and reflux uropathy
0.699 0.301 0.000
T85.2 Mechanical complication of intraocular lens
0.699 0.301 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.699 0.301 0.000
F99-F99 Unspecified mental disorder
0.699 0.301 0.000
Y43.1 Antineoplastic antimetabolites
0.699 0.301 0.000
E12 Malnutrition-related diabetes mellitus
0.699 0.301 0.000
N81.1 Cystocele
0.699 0.301 0.000
N25-N29 Other disorders of kidney and ureter
0.699 0.301 0.000
H65-H75 Diseases of middle ear and mastoid
0.698 0.302 0.000
N93 Other abnormal uterine and vaginal bleeding
0.698 0.302 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.698 0.302 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
Y35-Y36 Legal intervention and operations of war
0.697 0.303 0.000
Y10-Y34 Event of undetermined intent
0.697 0.303 0.000
Y00-Y09 Assault
0.697 0.303 0.000
X85-X99 Assault
0.697 0.303 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.697 0.303 0.000
X50-X57 Overexertion, travel and privation
0.697 0.303 0.000
X30-X39 Exposure to forces of nature
0.697 0.303 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.303 0.000
X10-X19 Contact with heat and hot substances
0.697 0.303 0.000
X00-X09 Exposure to smoke, fire and flames
0.697 0.303 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.697 0.303 0.000
W75-W84 Other accidental threats to breathing
0.697 0.303 0.000
W65-W74 Accidental drowning and submersion
0.697 0.303 0.000
W50-W64 Exposure to animate mechanical forces
0.697 0.303 0.000
V98-V99 Other and unspecified transport accidents
0.697 0.303 0.000
V95-V97 Air and space transport accidents
0.697 0.303 0.000
V90-V94 Water transport accidents
0.697 0.303 0.000
V80-V89 Other land transport accidents
0.697 0.303 0.000
V70-V79 Bus occupant injured in transport accident
0.697 0.303 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.697 0.303 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.697 0.303 0.000
V40-V49 Car occupant injured in transport accident
0.697 0.303 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.697 0.303 0.000
V10-V19 Pedal cyclist injured in transport accident
0.697 0.303 0.000
V01-V09 Pedestrian injured in transport accident
0.697 0.303 0.000
A49.9 Bacterial infection, unspecified
0.697 0.303 0.000
K52.3 Indeterminate colitis
0.696 0.304 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.696 0.304 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.696 0.304 0.000
S60-S69 Injuries to the wrist and hand
0.696 0.304 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.696 0.304 0.000
Z13.1 Special screening examination for diabetes mellitus
0.695 0.305 0.000
J03 Acute tonsillitis
0.694 0.306 0.000
E11.3 With ophthalmic complications
0.694 0.306 0.000
I35 Nonrheumatic aortic valve disorders
0.694 0.306 0.000
H53.0 Amblyopia ex anopsia
0.693 0.307 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.693 0.307 0.000
W00-W19 Falls
0.692 0.308 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.691 0.309 0.000
M54.1 Radiculopathy
0.691 0.309 0.000
N80.3 Endometriosis of pelvic peritoneum
0.691 0.309 0.000
A48 Other bacterial diseases, not elsewhere classified
0.689 0.310 0.000
A44 Bartonellosis
0.689 0.310 0.000
A43 Nocardiosis
0.689 0.310 0.000
A42 Actinomycosis
0.689 0.310 0.000
A40 Streptococcal septicaemia
0.689 0.310 0.000
A39 Meningococcal infection
0.689 0.310 0.000
A37 Whooping cough
0.689 0.310 0.000
A36 Diphtheria
0.689 0.310 0.000
A32 Listeriosis
0.689 0.310 0.000
A31 Infection due to other mycobacteria
0.689 0.310 0.000
A30 Leprosy [Hansen's disease]
0.689 0.310 0.000
A46 Erysipelas
0.689 0.310 0.000
A38 Scarlet fever
0.689 0.310 0.000
A35 Other tetanus
0.689 0.310 0.000
A34 Obstetrical tetanus
0.689 0.310 0.000
A33 Tetanus neonatorum
0.689 0.310 0.000
H43-H45 Disorders of vitreous body and globe
0.689 0.310 0.000
Y43.3 Other antineoplastic drugs
0.689 0.311 0.000
A41.8 Other specified septicaemia
0.689 0.311 0.000
B15-B19 Viral hepatitis
0.689 0.311 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.689 0.311 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.689 0.311 0.000
M48.06 Spinal stenosis (Lumbar region)
0.689 0.311 0.000
K50.1 Crohn's disease of large intestine
0.688 0.311 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.688 0.311 0.000
K82 Other diseases of gallbladder
0.688 0.312 0.000
T78 Adverse effects, not elsewhere classified
0.688 0.312 0.000
Z03.1 Observation for suspected malignant neoplasm
0.688 0.312 0.000
J20-J22 Other acute lower respiratory infections
0.687 0.313 0.000
K50.8 Other Crohn's disease
0.687 0.313 0.000
I52 Other heart disorders in diseases classified elsewhere
0.686 0.313 0.000
I48 Atrial fibrillation and flutter
0.686 0.313 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.686 0.313 0.000
I41 Myocarditis in diseases classified elsewhere
0.686 0.313 0.000
I40 Acute myocarditis
0.686 0.313 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.686 0.313 0.000
I37 Pulmonary valve disorders
0.686 0.313 0.000
I36 Nonrheumatic tricuspid valve disorders
0.686 0.313 0.000
I32 Pericarditis in diseases classified elsewhere
0.686 0.313 0.000
Z02 Examination and encounter for administrative purposes
0.686 0.314 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.685 0.315 0.000
H05 Disorders of orbit
0.685 0.315 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.685 0.315 0.000
Y57 Other and unspecified drugs and medicaments
0.685 0.315 0.000
K66 Other disorders of peritoneum
0.684 0.316 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.683 0.317 0.000
N81.4 Uterovaginal prolapse, unspecified
0.683 0.317 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.683 0.317 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.683 0.317 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.682 0.318 0.000
L50-L54 Urticaria and erythema
0.682 0.318 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.682 0.318 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.682 0.318 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.682 0.318 0.000
Z03.0 Observation for suspected tuberculosis
0.682 0.318 0.000
N87.0 Mild cervical dysplasia
0.682 0.318 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.681 0.319 0.000
I31.3 Pericardial effusion (noninflammatory)
0.681 0.319 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.680 0.319 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.680 0.320 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.680 0.320 0.000
H34 Retinal vascular occlusions
0.679 0.321 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.679 0.321 0.000
N81.8 Other female genital prolapse
0.678 0.322 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.678 0.322 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.677 0.322 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.677 0.322 0.000
G41 Status epilepticus
0.677 0.322 0.000
I84.4 External haemorrhoids with other complications
0.677 0.323 0.000
Q50-Q56 Congenital malformations of genital organs
0.677 0.323 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.677 0.323 0.000
K86 Other diseases of pancreas
0.677 0.323 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.676 0.323 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.676 0.324 0.000
E55 Vitamin D deficiency
0.676 0.324 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.676 0.324 0.000
Y59 Other and unspecified vaccines and biological substances
0.675 0.324 0.000
Y58 Bacterial vaccines
0.675 0.324 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.675 0.324 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.675 0.324 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.675 0.324 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.675 0.324 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.675 0.324 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.675 0.324 0.000
Y48 Anaesthetics and therapeutic gases
0.675 0.324 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.675 0.324 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.675 0.324 0.000
Y44 Agents primarily affecting blood constituents
0.675 0.324 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.675 0.324 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.675 0.325 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.675 0.325 0.000
H31 Other disorders of choroid
0.675 0.325 0.000
H30 Chorioretinal inflammation
0.675 0.325 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.675 0.325 0.000
F80-F89 Disorders of psychological development
0.675 0.325 0.000
F70-F79 Mental retardation
0.675 0.325 0.000
G43 Migraine
0.674 0.326 0.000
H40-H42 Glaucoma
0.674 0.326 0.000
K22 Other diseases of oesophagus
0.674 0.326 0.000
I42 Cardiomyopathy
0.673 0.326 0.000
I67 Other cerebrovascular diseases
0.672 0.328 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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