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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117932080
log Bayes Factor = 25.9049
Chromosome 15   position 93,875,227  (GRCh37) Explore rs117932080 on Ensembl!
Variant rs117932080 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
R50-R69 General symptoms and signs
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
M54.5 Low back pain
0.999 0.001 0.000
R30-R39 Symptoms and signs involving the urinary system
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
J30-J39 Other diseases of upper respiratory tract
0.999 0.001 0.000
J33 Nasal polyp
0.998 0.002 0.000
R53 Malaise and fatigue
0.997 0.003 0.000
J33.9 Nasal polyp, unspecified
0.996 0.004 0.000
M51 Other intervertebral disk disorders
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.993 0.007 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
M54.56 Low back pain (Lumbar region)
0.991 0.009 0.000
R35 Polyuria
0.989 0.011 0.000
M51.2 Other specified intervertebral disk displacement
0.987 0.013 0.000
R20 Disturbances of skin sensation
0.987 0.013 0.000
J47 Bronchiectasis
0.986 0.014 0.000
R33 Retention of urine
0.986 0.014 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.981 0.019 0.000
M54.59 Low back pain (Site unspecified)
0.980 0.020 0.000
Chapter XX External causes of morbidity and mortality
0.978 0.022 0.000
J44 Other chronic obstructive pulmonary disease
0.976 0.024 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.975 0.025 0.000
R20.2 Paraesthesia of skin
0.973 0.027 0.000
M20-M25 Other joint disorders
0.973 0.027 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.970 0.030 0.000
R55 Syncope and collapse
0.966 0.034 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.959 0.041 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.958 0.042 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.958 0.042 0.000
J09-J18 Influenza and pneumonia
0.958 0.042 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.953 0.047 0.000
F30-F39 Mood [affective] disorders
0.950 0.050 0.000
R54 Senility
0.947 0.053 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.945 0.055 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.942 0.058 0.000
Chapter VI Diseases of the nervous system
0.938 0.062 0.000
M45-M49 Spondylopathies
0.938 0.062 0.000
Chapter I Certain infectious and parasitic diseases
0.936 0.064 0.000
E70-E90 Metabolic disorders
0.931 0.069 0.000
R14 Flatulence and related conditions
0.925 0.075 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.923 0.077 0.000
M21 Other acquired deformities of limbs
0.922 0.078 0.000
M25 Other joint disorders, not elsewhere classified
0.919 0.081 0.000
J34 Other disorders of nose and nasal sinuses
0.915 0.085 0.000
E86 Volume depletion
0.915 0.085 0.000
S00-S09 Injuries to the head
0.914 0.086 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.910 0.090 0.000
R47-R49 Symptoms and signs involving speech and voice
0.907 0.093 0.000
M48 Other spondylopathies
0.907 0.093 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.901 0.099 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.895 0.105 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.887 0.113 0.000
F41 Other anxiety disorders
0.887 0.113 0.000
R45 Symptoms and signs involving emotional state
0.886 0.114 0.000
Chapter VIII Diseases of the ear and mastoid process
0.880 0.120 0.000
M48.0 Spinal stenosis
0.880 0.120 0.000
R15 Faecal incontinence
0.879 0.121 0.000
J18 Pneumonia, organism unspecified
0.879 0.121 0.000
Chapter II Neoplasms
0.879 0.121 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.878 0.122 0.000
J43 Emphysema
0.876 0.124 0.000
F32 Depressive episode
0.875 0.125 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.874 0.126 0.000
J35 Chronic diseases of tonsils and adenoids
0.871 0.129 0.000
R60 Oedema, not elsewhere classified
0.870 0.130 0.000
M48.06 Spinal stenosis (Lumbar region)
0.869 0.131 0.000
B95-B98 Bacterial, viral and other infectious agents
0.868 0.132 0.000
M54.2 Cervicalgia
0.864 0.136 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.861 0.139 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.861 0.139 0.000
J60-J70 Lung diseases due to external agents
0.857 0.143 0.000
M54.1 Radiculopathy
0.855 0.145 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.854 0.146 0.000
F99-F99 Unspecified mental disorder
0.854 0.146 0.000
M25.5 Pain in joint
0.849 0.151 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.848 0.152 0.000
R46 Symptoms and signs involving appearance and behaviour
0.845 0.155 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.844 0.156 0.000
R26 Abnormalities of gait and mobility
0.839 0.161 0.000
R49 Voice disturbances
0.837 0.163 0.000
C34 Malignant neoplasm of bronchus and lung
0.836 0.164 0.000
R51 Headache
0.829 0.171 0.000
M25.8 Other specified joint disorders
0.828 0.172 0.000
M80-M85 Disorders of bone density and structure
0.827 0.173 0.000
J33.0 Polyp of nasal cavity
0.825 0.175 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.819 0.181 0.000
Y52 Agents primarily affecting the cardiovascular system
0.817 0.183 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.817 0.183 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.816 0.184 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.814 0.186 0.000
R41.0 Disorientation, unspecified
0.814 0.186 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.812 0.188 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.812 0.188 0.000
M31 Other necrotising vasculopathies
0.811 0.189 0.000
R69 Unknown and unspecified causes of morbidity
0.810 0.190 0.000
G40-G47 Episodic and paroxysmal disorders
0.809 0.191 0.000
F33 Recurrent depressive disorder
0.807 0.193 0.000
T66-T78 Other and unspecified effects of external causes
0.807 0.193 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.807 0.193 0.000
R32 Unspecified urinary incontinence
0.806 0.194 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.806 0.194 0.000
R39 Other symptoms and signs involving the urinary system
0.806 0.194 0.000
S06 Intracranial injury
0.806 0.194 0.000
M51.9 Intervertebral disk disorder, unspecified
0.803 0.197 0.000
A30-A49 Other bacterial diseases
0.802 0.198 0.000
E20-E35 Disorders of other endocrine glands
0.802 0.198 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.798 0.202 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.798 0.202 0.000
R21 Rash and other nonspecific skin eruption
0.797 0.203 0.000
M24 Other specific joint derangements
0.797 0.203 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.797 0.203 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.795 0.205 0.000
Y40 Systemic antibiotics
0.795 0.205 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.795 0.205 0.000
J18.1 Lobar pneumonia, unspecified
0.794 0.206 0.000
G90-G99 Other disorders of the nervous system
0.793 0.207 0.000
T79-T79 Certain early complications of trauma
0.793 0.207 0.000
H80-H83 Diseases of inner ear
0.792 0.208 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.792 0.208 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.792 0.208 0.000
F43 Reaction to severe stress, and adjustment disorders
0.791 0.209 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.790 0.210 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.789 0.211 0.000
J43.9 Emphysema, unspecified
0.789 0.211 0.000
F41.2 Mixed anxiety and depressive disorder
0.789 0.211 0.000
Y43 Primarily systemic agents
0.788 0.212 0.000
J42 Unspecified chronic bronchitis
0.788 0.212 0.000
R49.0 Dysphonia
0.787 0.213 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.785 0.215 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.784 0.216 0.000
R16.1 Splenomegaly, not elsewhere classified
0.784 0.216 0.000
R42 Dizziness and giddiness
0.784 0.216 0.000
F45 Somatoform disorders
0.783 0.217 0.000
M91-M94 Chondropathies
0.782 0.217 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.782 0.218 0.000
R45.1 Restlessness and agitation
0.780 0.220 0.000
R57 Shock, not elsewhere classified
0.780 0.220 0.000
W50-W64 Exposure to animate mechanical forces
0.779 0.221 0.000
J40 Bronchitis, not specified as acute or chronic
0.779 0.221 0.000
S05 Injury of eye and orbit
0.777 0.223 0.000
S02 Fracture of skull and facial bones
0.777 0.223 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.776 0.224 0.000
R17 Unspecified jaundice
0.774 0.226 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.773 0.227 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.770 0.230 0.000
C34.3 Lower lobe, bronchus or lung
0.769 0.231 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.767 0.233 0.000
M54.22 Cervicalgia (Cervical region)
0.766 0.234 0.000
R10 Abdominal and pelvic pain
0.766 0.234 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.765 0.235 0.000
S90-S99 Injuries to the ankle and foot
0.765 0.235 0.000
J17 Pneumonia in diseases classified elsewhere
0.765 0.235 0.000
S10-S19 Injuries to the neck
0.763 0.237 0.000
R60.9 Oedema, unspecified
0.761 0.239 0.000
R94 Abnormal results of function studies
0.760 0.240 0.000
M51.8 Other specified intervertebral disk disorders
0.760 0.240 0.000
Y48 Anaesthetics and therapeutic gases
0.759 0.241 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.759 0.241 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.759 0.241 0.000
J90-J94 Other diseases of pleura
0.758 0.242 0.000
M65-M68 Disorders of synovium and tendon
0.758 0.242 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.758 0.242 0.000
R39.1 Other difficulties with micturition
0.757 0.243 0.000
C34.0 Main bronchus
0.756 0.244 0.000
G47 Sleep disorders
0.755 0.245 0.000
J37 Chronic laryngitis and laryngotracheitis
0.755 0.245 0.000
J34.3 Hypertrophy of nasal turbinates
0.755 0.245 0.000
M35 Other systemic involvement of connective tissue
0.754 0.246 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.754 0.246 0.000
F99 Mental disorder, not otherwise specified
0.752 0.248 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.752 0.248 0.000
M40-M43 Deforming dorsopathies
0.752 0.248 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.752 0.248 0.000
R68 Other general symptoms and signs
0.749 0.251 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.748 0.252 0.000
E88 Other metabolic disorders
0.748 0.252 0.000
G30-G32 Other degenerative diseases of the nervous system
0.747 0.253 0.000
R46.8 Other symptoms and signs involving appearance and behaviour
0.747 0.253 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.747 0.253 0.000
C91 Lymphoid leukaemia
0.746 0.254 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.746 0.254 0.000
F32.1 Moderate depressive episode
0.744 0.256 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.743 0.257 0.000
M21.6 Other acquired deformities of ankle and foot
0.743 0.257 0.000
Y44 Agents primarily affecting blood constituents
0.743 0.257 0.000
M54.16 Radiculopathy (Lumbar region)
0.743 0.257 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.743 0.257 0.000
E83 Disorders of mineral metabolism
0.742 0.258 0.000
X60-X84 Intentional self-harm
0.742 0.258 0.000
M54.3 Sciatica
0.740 0.259 0.000
B35-B49 Mycoses
0.740 0.260 0.000
M21.2 Flexion deformity
0.739 0.261 0.000
M25.3 Other instability of joint
0.738 0.262 0.000
F31 Bipolar affective disorder
0.738 0.262 0.000
J20-J22 Other acute lower respiratory infections
0.736 0.264 0.000
M21.3 Wrist or foot drop (acquired)
0.734 0.265 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.734 0.266 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.733 0.267 0.000
Chapter VII Diseases of the eye and adnexa
0.732 0.268 0.000
G47.3 Sleep apnoea
0.731 0.269 0.000
S40-S49 Injuries to the shoulder and upper arm
0.731 0.269 0.000
H90-H95 Other disorders of ear
0.730 0.270 0.000
F60-F69 Disorders of adult personality and behaviour
0.729 0.271 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.727 0.272 0.000
T92 Sequelae of injuries of upper limb
0.727 0.273 0.000
C45 Mesothelioma
0.727 0.273 0.000
V40-V49 Car occupant injured in transport accident
0.726 0.274 0.000
T40.2 Other opioids
0.726 0.274 0.000
W00-W19 Falls
0.725 0.275 0.000
J95-J99 Other diseases of the respiratory system
0.725 0.275 0.000
R45.8 Other symptoms and signs involving emotional state
0.723 0.277 0.000
M25.52 Pain in joint (Upper arm)
0.723 0.277 0.000
M54.4 Lumbago with sciatica
0.723 0.277 0.000
M00-M03 Infectious arthropathies
0.723 0.277 0.000
M15-M19 Arthrosis
0.722 0.278 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.720 0.280 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.719 0.281 0.000
M25.56 Pain in joint (Lower leg)
0.718 0.282 0.000
M86-M90 Other osteopathies
0.718 0.282 0.000
M53 Other dorsopathies, not elsewhere classified
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.717 0.283 0.000
R62 Lack of expected normal physiological development
0.717 0.283 0.000
R64 Cachexia
0.717 0.283 0.000
R58 Haemorrhage, not elsewhere classified
0.717 0.283 0.000
S00 Superficial injury of head
0.717 0.283 0.000
M54.8 Other dorsalgia
0.717 0.283 0.000
M54.6 Pain in thoracic spine
0.717 0.283 0.000
M54.0 Panniculitis affecting regions of neck and back
0.717 0.283 0.000
M54.55 Low back pain (Thoracolumbar region)
0.716 0.284 0.000
M54.54 Low back pain-Thoracic
0.716 0.284 0.000
M54.53 Low back pain-Cervicothoracic
0.716 0.284 0.000
M54.52 Low back pain-Cervical
0.716 0.284 0.000
M54.51 Low back pain-Occipit-atl-axl
0.716 0.284 0.000
M54.50 Low back pain (Multiple sites in spine)
0.716 0.284 0.000
R36 Urethral discharge
0.716 0.284 0.000
R34 Anuria and oliguria
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
V20-V29 Motorcycle rider injured in transport accident
0.716 0.284 0.000
M21.1 Varus deformity, not elsewhere classified
0.716 0.284 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.715 0.284 0.000
J33.1 Polypoid sinus degeneration
0.715 0.285 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.715 0.285 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.714 0.285 0.000
M51.3 Other specified intervertebral disk degeneration
0.714 0.286 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.714 0.286 0.000
M51.4 Schmorl's nodes
0.714 0.286 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.714 0.286 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F80-F89 Disorders of psychological development
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.713 0.287 0.000
J35.0 Chronic tonsillitis
0.712 0.288 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
S36 Injury of intra-abdominal organs
0.711 0.289 0.000
Chapter XXII Codes for special purposes
0.711 0.289 0.000
M21.4 Flat foot [pes planus] (acquired)
0.710 0.289 0.000
M34 Systemic sclerosis
0.710 0.289 0.000
M70-M79 Other soft tissue disorders
0.710 0.290 0.000
M05-M14 Inflammatory polyarthropathies
0.709 0.291 0.000
F40 Phobic anxiety disorders
0.708 0.292 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.708 0.292 0.000
R20.3 Hyperaesthesia
0.707 0.293 0.000
R20.1 Hypoaesthesia of skin
0.707 0.293 0.000
R20.0 Anaesthesia of skin
0.707 0.293 0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.707 0.293 0.000
Y45.0 Opioids and related analgesics
0.707 0.293 0.000
G93 Other disorders of brain
0.707 0.293 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.707 0.293 0.000
G20-G26 Extrapyramidal and movement disorders
0.706 0.294 0.000
G70-G73 Diseases of myoneural junction and muscle
0.706 0.294 0.000
L05 Pilonidal cyst
0.705 0.295 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.705 0.295 0.000
E87.0 Hyperosmolality and hypernatraemia
0.704 0.296 0.000
T90 Sequelae of injuries of head
0.704 0.296 0.000
J11 Influenza, virus not identified
0.704 0.296 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.704 0.296 0.000
R43 Disturbances of smell and taste
0.704 0.296 0.000
E40-E46 Malnutrition
0.703 0.296 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.701 0.299 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.701 0.299 0.000
Y35-Y36 Legal intervention and operations of war
0.701 0.299 0.000
Y10-Y34 Event of undetermined intent
0.701 0.299 0.000
Y00-Y09 Assault
0.701 0.299 0.000
X85-X99 Assault
0.701 0.299 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.701 0.299 0.000
X50-X57 Overexertion, travel and privation
0.701 0.299 0.000
X30-X39 Exposure to forces of nature
0.701 0.299 0.000
X20-X29 Contact with venomous animals and plants
0.701 0.299 0.000
X10-X19 Contact with heat and hot substances
0.701 0.299 0.000
X00-X09 Exposure to smoke, fire and flames
0.701 0.299 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.701 0.299 0.000
W75-W84 Other accidental threats to breathing
0.701 0.299 0.000
W65-W74 Accidental drowning and submersion
0.701 0.299 0.000
V98-V99 Other and unspecified transport accidents
0.701 0.299 0.000
V95-V97 Air and space transport accidents
0.701 0.299 0.000
V90-V94 Water transport accidents
0.701 0.299 0.000
V70-V79 Bus occupant injured in transport accident
0.701 0.299 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.701 0.299 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.701 0.299 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.701 0.299 0.000
V01-V09 Pedestrian injured in transport accident
0.701 0.299 0.000
B15-B19 Viral hepatitis
0.701 0.299 0.000
C79 Secondary malignant neoplasm of other sites
0.701 0.299 0.000
T40.4 Other synthetic narcotics
0.699 0.301 0.000
R29.6 Tendency to fall, not elsewhere classified
0.699 0.301 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.699 0.301 0.000
F33.9 Recurrent depressive disorder, unspecified
0.698 0.302 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.698 0.302 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.697 0.302 0.000
M33 Dermatopolymyositis
0.697 0.302 0.000
M32 Systemic lupus erythematosus
0.697 0.302 0.000
M30 Polyarteritis nodosa and related conditions
0.697 0.302 0.000
B65-B83 Helminthiases
0.695 0.304 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.695 0.305 0.000
M25.50 Pain in joint (Multiple sites)
0.695 0.305 0.000
C34.9 Bronchus or lung, unspecified
0.695 0.305 0.000
T91 Sequelae of injuries of neck and trunk
0.694 0.306 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.694 0.306 0.000
M21.0 Valgus deformity, not elsewhere classified
0.692 0.307 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.691 0.309 0.000
C80 Malignant neoplasm without specification of site
0.691 0.309 0.000
M31.6 Other giant cell arteritis
0.690 0.310 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.690 0.310 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.690 0.310 0.000
R41.3 Other amnesia
0.690 0.310 0.000
Y40.0 Penicillins
0.688 0.312 0.000
R61 Hyperhidrosis
0.687 0.313 0.000
Q60-Q64 Congenital malformations of the urinary system
0.687 0.313 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.687 0.313 0.000
F48 Other neurotic disorders
0.687 0.313 0.000
F44 Dissociative [conversion] disorders
0.687 0.313 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.687 0.313 0.000
J12 Viral pneumonia, not elsewhere classified
0.687 0.313 0.000
J14 Pneumonia due to Haemophilus influenzae
0.687 0.313 0.000
J09 Influenza due to certain identified influenza virus
0.687 0.313 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.686 0.313 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.686 0.313 0.000
J18.9 Pneumonia, unspecified
0.686 0.314 0.000
A49 Bacterial infection of unspecified site
0.686 0.314 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.685 0.315 0.000
J86 Pyothorax
0.685 0.315 0.000
H91 Other hearing loss
0.683 0.317 0.000
Y59 Other and unspecified vaccines and biological substances
0.683 0.317 0.000
Y58 Bacterial vaccines
0.683 0.317 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.683 0.317 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.683 0.317 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.683 0.317 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.683 0.317 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.683 0.317 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.683 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.683 0.317 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.683 0.317 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.683 0.317 0.000
J69 Pneumonitis due to solids and liquids
0.683 0.317 0.000
F42 Obsessive-compulsive disorder
0.683 0.317 0.000
M80 Osteoporosis with pathological fracture
0.682 0.318 0.000
F38 Other mood [affective] disorders
0.681 0.319 0.000
F34 Persistent mood [affective] disorders
0.681 0.319 0.000
F30 Manic episode
0.681 0.319 0.000
F39 Unspecified mood [affective] disorder
0.681 0.319 0.000
J33.8 Other polyp of sinus
0.681 0.319 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.681 0.319 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.680 0.320 0.000
R50 Fever of unknown origin
0.679 0.321 0.000
F32.9 Depressive episode, unspecified
0.679 0.321 0.000
J10 Influenza due to identified influenza virus
0.678 0.322 0.000
M45 Ankylosing spondylitis
0.678 0.322 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.677 0.322 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.677 0.322 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.677 0.322 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.677 0.322 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.677 0.322 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.677 0.322 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.677 0.322 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.677 0.322 0.000
T36 Poisoning by systemic antibiotics
0.677 0.322 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.677 0.323 0.000
T98 Sequelae of other and unspecified effects of external causes
0.676 0.324 0.000
H81 Disorders of vestibular function
0.675 0.325 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.674 0.325 0.000
E87.7 Fluid overload
0.674 0.326 0.000
T78 Adverse effects, not elsewhere classified
0.674 0.326 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.674 0.326 0.000
J39 Other diseases of upper respiratory tract
0.674 0.326 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.673 0.327 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.673 0.327 0.000
M49 Spondylopathies in diseases classified elsewhere
0.672 0.328 0.000
M25.9 Joint disorder, unspecified
0.672 0.328 0.000
G41 Status epilepticus
0.672 0.328 0.000
B99-B99 Other infectious diseases
0.671 0.329 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.671 0.329 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.671 0.329 0.000
B50-B64 Protozoal diseases
0.671 0.329 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.671 0.329 0.000
A75-A79 Rickettsioses
0.671 0.329 0.000
A70-A74 Other diseases caused by chlamydiae
0.671 0.329 0.000
A65-A69 Other spirochaetal diseases
0.671 0.329 0.000
A20-A28 Certain zoonotic bacterial diseases
0.671 0.329 0.000
A15-A19 Tuberculosis
0.671 0.329 0.000
H60-H62 Diseases of external ear
0.671 0.329 0.000
R10.3 Pain localised to other parts of lower abdomen
0.671 0.329 0.000
T39.0 Salicylates
0.671 0.329 0.000
F43.2 Adjustment disorders
0.671 0.329 0.000
R19.5 Other fecal abnormalities
0.670 0.330 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.670 0.330 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.670 0.330 0.000
M67 Other disorders of synovium and tendon
0.669 0.331 0.000
J15.4 Pneumonia due to other streptococci
0.669 0.331 0.000
E85 Amyloidosis
0.668 0.332 0.000
E84 Cystic fibrosis
0.668 0.332 0.000
E79 Disorders of purine and pyrimidine metabolism
0.668 0.332 0.000
E77 Disorders of glycoprotein metabolism
0.668 0.332 0.000
E76 Disorders of glycosaminoglycan metabolism
0.668 0.332 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.668 0.332 0.000
E74 Other disorders of carbohydrate metabolism
0.668 0.332 0.000
E73 Lactose intolerance
0.668 0.332 0.000
E72 Other disorders of amino-acid metabolism
0.668 0.332 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.668 0.332 0.000
E70 Disorders of aromatic amino-acid metabolism
0.668 0.332 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.668 0.332 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.667 0.333 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.666 0.333 0.000
M16 Coxarthrosis [arthrosis of hip]
0.665 0.335 0.000
R47 Speech disturbances, not elsewhere classified
0.665 0.335 0.000
J18.0 Bronchopneumonia, unspecified
0.665 0.335 0.000
T93 Sequelae of injuries of lower limb
0.665 0.335 0.000
S70-S79 Injuries to the hip and thigh
0.665 0.335 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.665 0.335 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.661 0.339 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.661 0.339 0.000
M84 Disorders of continuity of bone
0.661 0.339 0.000
M21.9 Acquired deformity of limb, unspecified
0.661 0.339 0.000
M21.8 Other specified acquired deformities of limbs
0.661 0.339 0.000
M21.7 Unequal limb length (acquired)
0.661 0.339 0.000
M54.57 Low back pain (Lumbosacral region)
0.660 0.340 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.660 0.340 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.660 0.340 0.000
H83 Other diseases of inner ear
0.660 0.340 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.659 0.341 0.000
F32.0 Mild depressive episode
0.659 0.341 0.000
R27 Other lack of coordination
0.659 0.341 0.000
M25.2 Flail joint
0.659 0.341 0.000
M25.1 Fistula of joint
0.659 0.341 0.000
M25.0 Haemarthrosis
0.659 0.341 0.000
F45.8 Other somatoform disorders
0.658 0.342 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.658 0.342 0.000
R60.0 Localised oedema
0.658 0.342 0.000
R30 Pain associated with micturition
0.658 0.342 0.000
E23 Hypofunction and other disorders of pituitary gland
0.657 0.342 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.656 0.344 0.000
C88 Malignant immunoproliferative diseases
0.656 0.344 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.656 0.344 0.000
E87.2 Acidosis
0.655 0.345 0.000
S08 Traumatic amputation of part of head
0.655 0.345 0.000
S07 Crushing injury of head
0.655 0.345 0.000
S04 Injury of cranial nerves
0.655 0.345 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.655 0.345 0.000
Y95 Nosocomial condition
0.655 0.345 0.000
J36 Peritonsillar abscess
0.654 0.346 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.654 0.346 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.653 0.347 0.000
C34.2 Middle lobe, bronchus or lung
0.653 0.347 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.653 0.347 0.000
R40 Somnolence, stupor and coma
0.653 0.347 0.000
A80-A89 Viral infections of the central nervous system
0.653 0.347 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.652 0.347 0.000
S37 Injury of urinary and pelvic organs
0.652 0.347 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.652 0.347 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.652 0.347 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.652 0.347 0.000
S31 Open wound of abdomen, lower back and pelvis
0.652 0.347 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.652 0.348 0.000
S06.5 Traumatic subdural haemorrhage
0.652 0.348 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.650 0.349 0.000
H91.9 Hearing loss, unspecified
0.650 0.350 0.000
M48.9 Spondylopathy, unspecified
0.650 0.350 0.000
M48.8 Other specified spondylopathies
0.650 0.350 0.000
M48.4 Fatigue fracture of vertebra
0.650 0.350 0.000
M48.3 Traumatic spondylopathy
0.650 0.350 0.000
M48.2 Kissing spine
0.650 0.350 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.650 0.350 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.650 0.350 0.000
S06.2 Diffuse brain injury
0.649 0.351 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.649 0.351 0.000
L57.0 Actinic keratosis
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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