TreeWAS – Variant ID: rs117982023

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter I Certain infectious and parasitic diseases	1.000	0.000
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	1.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
Chapter XX External causes of morbidity and mortality	0.997	0.003
A00-A09 Intestinal infectious diseases	0.996	0.004
B95-B98 Bacterial, viral and other infectious agents	0.996	0.004
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.996	0.004
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.995	0.005
A04 Other bacterial intestinal infections	0.993	0.007
A04.8 Other specified bacterial intestinal infections	0.991	0.009
G40-G47 Episodic and paroxysmal disorders	0.990	0.010
Chapter IV Endocrine, nutritional and metabolic diseases	0.990	0.010
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.989	0.011
M20-M25 Other joint disorders	0.989	0.011
Chapter XV Pregnancy, childbirth and the puerperium	0.986	0.014
R07 Pain in throat and chest	0.984	0.016
Chapter IX Diseases of the circulatory system	0.982	0.018
E70-E90 Metabolic disorders	0.979	0.021
G40 Epilepsy	0.972	0.028
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.967	0.033
Chapter XII Diseases of the skin and subcutaneous tissue	0.965	0.035
I30-I52 Other forms of heart disease	0.963	0.037
E86 Volume depletion	0.963	0.037
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.962	0.038
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.961	0.039
R05 Cough	0.958	0.042
R02 Gangrene, not elsewhere classified	0.954	0.046
R07.3 Other chest pain	0.951	0.049
M25 Other joint disorders, not elsewhere classified	0.951	0.049
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.946	0.054
G40.9 Epilepsy, unspecified	0.943	0.057
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.941	0.059
G47 Sleep disorders	0.940	0.060
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.939	0.061
B35-B49 Mycoses	0.934	0.066
R03 Abnormal blood-pressure reading, without diagnosis	0.928	0.072
M24 Other specific joint derangements	0.927	0.073
E87 Other disorders of fluid, electrolyte and acid-base balance	0.924	0.076
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.924	0.076
S00-S09 Injuries to the head	0.919	0.081
Y83.6 Removal of other organ (partial) (total)	0.913	0.087
R00 Abnormalities of heart beat	0.910	0.090
S80-S89 Injuries to the knee and lower leg	0.908	0.092
I05-I09 Chronic rheumatic heart diseases	0.907	0.093
G47.3 Sleep apnoea	0.907	0.093
R42 Dizziness and giddiness	0.906	0.094
Chapter X Diseases of the respiratory system	0.903	0.097
I47 Paroxysmal tachycardia	0.902	0.098
M80-M85 Disorders of bone density and structure	0.901	0.099
G80-G83 Cerebral palsy and other paralytic syndromes	0.899	0.101
I95-I99 Other and unspecified disorders of the circulatory system	0.898	0.102
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.898	0.102
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.893	0.107
L40-L45 Papulosquamous disorders	0.893	0.107
Y83.1 Surgical operation with implant of artificial internal device	0.891	0.109
S90-S99 Injuries to the ankle and foot	0.888	0.112
R07.0 Pain in throat	0.887	0.113
I60-I69 Cerebrovascular diseases	0.885	0.115
J44 Other chronic obstructive pulmonary disease	0.885	0.115
J40-J47 Chronic lower respiratory diseases	0.883	0.117
J44.9 Chronic obstructive pulmonary disease, unspecified	0.883	0.117
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.882	0.118
R45 Symptoms and signs involving emotional state	0.882	0.118
V10-V19 Pedal cyclist injured in transport accident	0.882	0.118
I51 Complications and ill-defined descriptions of heart disease	0.881	0.119
L80-L99 Other disorders of the skin and subcutaneous tissue	0.879	0.121
A30-A49 Other bacterial diseases	0.875	0.125
G90-G99 Other disorders of the nervous system	0.866	0.134
G62 Other polyneuropathies	0.865	0.135
R00.2 Palpitations	0.863	0.137
I69 Sequelae of cerebrovascular disease	0.861	0.139
M84 Disorders of continuity of bone	0.858	0.142
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.856	0.144
B37 Candidiasis	0.855	0.145
I50 Heart failure	0.854	0.146
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.850	0.150
O47 False labour	0.848	0.152
M25.7 Osteophyte	0.848	0.152
E50-E64 Other nutritional deficiencies	0.845	0.155
I95 Hypotension	0.843	0.157
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.843	0.157
B20-B24 Human immunodeficiency virus [HIV] disease	0.843	0.157
M50-M54 Other dorsopathies	0.843	0.157
G60 Hereditary and idiopathic neuropathy	0.842	0.158
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.842	0.158
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.839	0.161
E87.2 Acidosis	0.837	0.163
J09-J18 Influenza and pneumonia	0.836	0.164
M86-M90 Other osteopathies	0.834	0.166
I08 Multiple valve diseases	0.831	0.169
I49 Other cardiac arrhythmias	0.829	0.171
S00 Superficial injury of head	0.828	0.172
S82 Fracture of lower leg, including ankle	0.828	0.172
D70-D77 Other diseases of blood and blood-forming organs	0.826	0.174
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.825	0.175
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.824	0.175
E16 Other disorders of pancreatic internal secretion	0.824	0.176
L60-L75 Disorders of skin appendages	0.824	0.176
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.823	0.177
D80-D89 Certain disorders involving the immune mechanism	0.822	0.178
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.819	0.181
M24.1 Other articular cartilage disorders	0.814	0.186
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.814	0.186
I95.9 Hypotension, unspecified	0.812	0.188
R00.0 Tachycardia, unspecified	0.812	0.188
M24.2 Disorder of ligament	0.811	0.189
R45.1 Restlessness and agitation	0.808	0.192
L40 Psoriasis	0.805	0.195
I47.1 Supraventricular tachycardia	0.804	0.196
R25 Abnormal involuntary movements	0.803	0.197
L92 Granulomatous disorders of skin and subcutaneous tissue	0.801	0.199
V18 Pedal cyclist injured in noncollision transport accident	0.800	0.200
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.800	0.200
B50-B64 Protozoal diseases	0.798	0.202
O94-O99 Other obstetric conditions, not elsewhere classified	0.798	0.202
O60-O75 Complications of labour and delivery	0.797	0.203
E20-E35 Disorders of other endocrine glands	0.796	0.204
I08.1 Disorders of both mitral and tricuspid valves	0.796	0.204
R26 Abnormalities of gait and mobility	0.795	0.205
I51.7 Cardiomegaly	0.795	0.205
S10-S19 Injuries to the neck	0.794	0.206
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.793	0.207
E87.3 Alkalosis	0.793	0.207
G30-G32 Other degenerative diseases of the nervous system	0.792	0.208
G62.9 Polyneuropathy, unspecified	0.791	0.209
S50-S59 Injuries to the elbow and forearm	0.785	0.215
M84.1 Nonunion of fracture [pseudarthrosis]	0.783	0.217
B44 Aspergillosis	0.783	0.217
G44 Other headache syndromes	0.782	0.218
M23 Internal derangement of knee	0.781	0.219
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.781	0.219
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.780	0.220
X60-X84 Intentional self-harm	0.779	0.220
M22 Disorders of patella	0.779	0.221
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.777	0.223
G61 Inflammatory polyneuropathy	0.777	0.223
S92 Fracture of foot, except ankle	0.777	0.223
E16.2 Hypoglycaemia, unspecified	0.775	0.225
M70-M79 Other soft tissue disorders	0.775	0.225
M20 Acquired deformities of fingers and toes	0.774	0.226
A04.5 Campylobacter enteritis	0.773	0.227
O20-O29 Other maternal disorders predominantly related to pregnancy	0.773	0.227
E53 Deficiency of other B group vitamins	0.772	0.228
O85-O92 Complications predominantly related to the puerperium	0.770	0.230
I49.9 Cardiac arrhythmia, unspecified	0.770	0.230
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.769	0.231
R07.4 Chest pain, unspecified	0.769	0.231
S00.8 Superficial injury of other parts of head	0.767	0.233
B15-B19 Viral hepatitis	0.767	0.233
M25.8 Other specified joint disorders	0.766	0.234
A80-A89 Viral infections of the central nervous system	0.763	0.236
R93 Abnormal findings on diagnostic imaging of other body structures	0.763	0.237
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.763	0.237
I37 Pulmonary valve disorders	0.763	0.237
G81 Hemiplegia	0.763	0.237
I50.0 Congestive heart failure	0.762	0.238
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.762	0.238
M21 Other acquired deformities of limbs	0.760	0.240
M51 Other intervertebral disk disorders	0.760	0.240
S09 Other and unspecified injuries of head	0.758	0.242
M84.0 Malunion of fracture	0.758	0.242
L50-L54 Urticaria and erythema	0.757	0.243
R27 Other lack of coordination	0.757	0.243
G60.0 Hereditary motor and sensory neuropathy	0.757	0.243
L84 Corns and callosities	0.757	0.243
A41 Other septicaemia	0.757	0.243
O47.9 False labour, unspecified	0.756	0.244
I31 Other diseases of pericardium	0.754	0.246
M91-M94 Chondropathies	0.754	0.246
W00-W19 Falls	0.753	0.247
J95-J99 Other diseases of the respiratory system	0.752	0.248
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.752	0.248
V40-V49 Car occupant injured in transport accident	0.752	0.248
S02 Fracture of skull and facial bones	0.751	0.248
I47.2 Ventricular tachycardia	0.750	0.250
M40-M43 Deforming dorsopathies	0.750	0.250
E40-E46 Malnutrition	0.749	0.251
M25.0 Haemarthrosis	0.749	0.251
A50-A64 Infections with a predominantly sexual mode of transmission	0.748	0.252
G40.8 Other epilepsy	0.748	0.252
Chapter XXII Codes for special purposes	0.748	0.252
L43 Lichen planus	0.748	0.252
B99-B99 Other infectious diseases	0.747	0.253
V80-V89 Other land transport accidents	0.747	0.253
M25.3 Other instability of joint	0.747	0.253
Y60-Y69 Misadventures to patients during surgical and medical care	0.745	0.255
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.745	0.255
E87.5 Hyperkalaemia	0.744	0.256
T93 Sequelae of injuries of lower limb	0.744	0.256
I33 Acute and subacute endocarditis	0.742	0.258
V18.0 Driver injured in nontraffic accident	0.741	0.259
M05-M14 Inflammatory polyarthropathies	0.740	0.260
O47.1 False labour at or after 37 completed weeks of gestation	0.740	0.260
O40 Polyhydramnios	0.739	0.261
S82.1 Fracture of upper end of tibia	0.737	0.263
Q60-Q64 Congenital malformations of the urinary system	0.737	0.263
O44 Placenta praevia	0.736	0.264
Q50-Q56 Congenital malformations of genital organs	0.735	0.264
L60 Nail disorders	0.734	0.266
M25.75 Osteophyte (Pelvic region and thigh)	0.734	0.266
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.734	0.266
L20-L30 Dermatitis and eczema	0.733	0.267
J15 Bacterial pneumonia, not elsewhere classified	0.733	0.267
B37.3 Candidiasis of vulva and vagina	0.731	0.269
B24 Unspecified human immunodeficiency virus [HIV] disease	0.730	0.269
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.730	0.270
E73 Lactose intolerance	0.730	0.270
G99 Other disorders of nervous system in diseases classified elsewhere	0.729	0.271
I42 Cardiomyopathy	0.729	0.271
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.728	0.272
M25.5 Pain in joint	0.727	0.273
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.727	0.273
L73 Other follicular disorders	0.727	0.273
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.727	0.273
G82 Paraplegia and tetraplegia	0.726	0.274
R07.1 Chest pain on breathing	0.726	0.274
S20-S29 Injuries to the thorax	0.725	0.275
L40.5 Arthropathic psoriasis	0.725	0.275
L97 Ulcer of lower limb, not elsewhere classified	0.724	0.276
T81 Complications of procedures, not elsewhere classified	0.723	0.277
I69.3 Sequelae of cerebral infarction	0.723	0.277
G00-G09 Inflammatory diseases of the central nervous system	0.722	0.277
M00-M03 Infectious arthropathies	0.722	0.278
I38 Endocarditis, valve unspecified	0.722	0.278
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.722	0.278
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.722	0.278
O34 Maternal care for known or suspected abnormality of pelvic organs	0.721	0.279
I05 Rheumatic mitral valve diseases	0.721	0.279
M25.4 Effusion of joint	0.720	0.280
E53.8 Deficiency of other specified B group vitamins	0.719	0.281
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.719	0.281
G95 Other diseases of spinal cord	0.718	0.282
B90-B94 Sequelae of infectious and parasitic diseases	0.717	0.283
B85-B89 Pediculosis, acariasis and other infestations	0.717	0.283
B65-B83 Helminthiases	0.717	0.283
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283
A75-A79 Rickettsioses	0.717	0.283
A70-A74 Other diseases caused by chlamydiae	0.717	0.283
A65-A69 Other spirochaetal diseases	0.717	0.283
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283
A15-A19 Tuberculosis	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
E80 Disorders of porphyrin and bilirubin metabolism	0.717	0.283
R01 Cardiac murmurs and other cardiac sounds	0.717	0.283
B37.9 Candidiasis, unspecified	0.716	0.284
D68 Other coagulation defects	0.716	0.284
Y83.9 Surgical procedure, unspecified	0.716	0.284
V20-V29 Motorcycle rider injured in transport accident	0.715	0.285
M60-M63 Disorders of muscles	0.715	0.285
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.714	0.285
Y35-Y36 Legal intervention and operations of war	0.714	0.285
Y10-Y34 Event of undetermined intent	0.714	0.285
Y00-Y09 Assault	0.714	0.285
X85-X99 Assault	0.714	0.285
X58-X59 Accidental exposure to other and unspecified factors	0.714	0.285
X50-X57 Overexertion, travel and privation	0.714	0.285
X40-X49 Accidental poisoning by and exposure to noxious substances	0.714	0.285
X30-X39 Exposure to forces of nature	0.714	0.285
X20-X29 Contact with venomous animals and plants	0.714	0.285
X10-X19 Contact with heat and hot substances	0.714	0.285
X00-X09 Exposure to smoke, fire and flames	0.714	0.285
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.714	0.285
W75-W84 Other accidental threats to breathing	0.714	0.285
W65-W74 Accidental drowning and submersion	0.714	0.285
W50-W64 Exposure to animate mechanical forces	0.714	0.285
V98-V99 Other and unspecified transport accidents	0.714	0.285
V95-V97 Air and space transport accidents	0.714	0.285
V90-V94 Water transport accidents	0.714	0.285
V70-V79 Bus occupant injured in transport accident	0.714	0.285
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.714	0.285
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.714	0.285
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.714	0.285
V01-V09 Pedestrian injured in transport accident	0.714	0.285
A07 Other protozoal intestinal diseases	0.714	0.286
A06 Amoebiasis	0.714	0.286
A05 Other bacterial foodborne intoxications	0.714	0.286
A03 Shigellosis	0.714	0.286
A02 Other Salmonella infections	0.714	0.286
A01 Typhoid and paratyphoid fevers	0.714	0.286
A00 Cholera	0.714	0.286
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.714	0.286
D50-D53 Nutritional anaemias	0.712	0.288
A04.9 Bacterial intestinal infection, unspecified	0.712	0.288
A04.6 Enteritis due to Yersinia enterocolitica	0.712	0.288
A04.4 Other intestinal Escherichia coli infections	0.712	0.288
A04.3 Enterohaemorrhagic Escherichia coli infection	0.712	0.288
A04.2 Enteroinvasive Escherichia coli infection	0.712	0.288
A04.1 Enterotoxigenic Escherichia coli infection	0.712	0.288
A04.0 Enteropathogenic Escherichia coli infection	0.712	0.288
M25.74 Osteophyte (Hand)	0.711	0.289
I50.9 Heart failure, unspecified	0.710	0.290
G46 Vascular syndromes of brain in cerebrovascular diseases	0.710	0.290
G41 Status epilepticus	0.710	0.290
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.709	0.291
T33-T35 Frostbite	0.709	0.291
T26-T28 Burns and corrosions confined to eye and internal organs	0.709	0.291
T20-T25 Burns and corrosions of external body surface, specified by site	0.709	0.291
T00-T07 Injuries involving multiple body regions	0.709	0.291
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.709	0.291
M34 Systemic sclerosis	0.709	0.291
M33 Dermatopolymyositis	0.709	0.291
M32 Systemic lupus erythematosus	0.709	0.291
M30 Polyarteritis nodosa and related conditions	0.709	0.291
R44 Other symptoms and signs involving general sensations and perceptions	0.709	0.291
S80 Superficial injury of lower leg	0.707	0.293
Y46 Antiepileptics and anti-Parkinsonism drugs	0.706	0.294
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.705	0.295
L90 Atrophic disorders of skin	0.705	0.295
M75 Shoulder lesions	0.705	0.295
I64 Stroke, not specified as haemorrhage or infarction	0.704	0.296
T81.4 Infection following a procedure, not elsewhere classified	0.704	0.296
E88 Other metabolic disorders	0.704	0.296
I00-I02 Acute rheumatic fever	0.704	0.296
A09.9 Gastroenteritis and colitis of unspecified origin	0.704	0.296
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.703	0.296
D86 Sarcoidosis	0.703	0.297
Chapter V Mental and behavioural disorders	0.703	0.297
G83 Other paralytic syndromes	0.702	0.298
E85 Amyloidosis	0.702	0.298
E84 Cystic fibrosis	0.702	0.298
E79 Disorders of purine and pyrimidine metabolism	0.702	0.298
E77 Disorders of glycoprotein metabolism	0.702	0.298
E76 Disorders of glycosaminoglycan metabolism	0.702	0.298
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.702	0.298
E74 Other disorders of carbohydrate metabolism	0.702	0.298
E72 Other disorders of amino-acid metabolism	0.702	0.298
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.702	0.298
E70 Disorders of aromatic amino-acid metabolism	0.702	0.298
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.702	0.298
O00-O08 Pregnancy with abortive outcome	0.702	0.298
M24.8 Other specific joint derangements, not elsewhere classified	0.702	0.298
G63 Polyneuropathy in diseases classified elsewhere	0.701	0.299
I47.0 Reentry ventricular arrhythmia	0.700	0.300
S60-S69 Injuries to the wrist and hand	0.699	0.301
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.699	0.301
B25-B34 Other viral diseases	0.699	0.301
S90 Superficial injury of ankle and foot	0.699	0.301
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.698	0.302
D70 Agranulocytosis	0.697	0.303
M25.9 Joint disorder, unspecified	0.697	0.303
I36 Nonrheumatic tricuspid valve disorders	0.697	0.303
G40.7 Petit mal, unspecified, without grand mal seizures	0.697	0.303
G40.5 Special epileptic syndromes	0.697	0.303
G40.4 Other generalised epilepsy and epileptic syndromes	0.697	0.303
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.697	0.303
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.696	0.304
Y52 Agents primarily affecting the cardiovascular system	0.696	0.304
G70-G73 Diseases of myoneural junction and muscle	0.696	0.304
E87.7 Fluid overload	0.696	0.304
S05 Injury of eye and orbit	0.695	0.305
M23.8 Other internal derangements of knee	0.694	0.306
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.694	0.306
I60 Subarachnoid haemorrhage	0.693	0.307
O48 Prolonged pregnancy	0.693	0.307
I61 Intracerebral haemorrhage	0.692	0.308
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.692	0.308
L10-L14 Bullous disorders	0.692	0.308
I52 Other heart disorders in diseases classified elsewhere	0.691	0.309
I48 Atrial fibrillation and flutter	0.691	0.309
I43 Cardiomyopathy in diseases classified elsewhere	0.691	0.309
I41 Myocarditis in diseases classified elsewhere	0.691	0.309
I40 Acute myocarditis	0.691	0.309
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.691	0.309
I32 Pericarditis in diseases classified elsewhere	0.691	0.309
I95.2 Hypotension due to drugs	0.690	0.310
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.690	0.310
R46 Symptoms and signs involving appearance and behaviour	0.690	0.310
R43 Disturbances of smell and taste	0.690	0.310
G64 Other disorders of peripheral nervous system	0.689	0.311
M25.77 Osteophyte (Ankle and foot)	0.689	0.311
R45.8 Other symptoms and signs involving emotional state	0.689	0.311
A49 Bacterial infection of unspecified site	0.689	0.311
M24.0 Loose body in joint	0.689	0.311
M24.24 Disorder of ligament (Hand)	0.688	0.312
M75.4 Impingement syndrome of shoulder	0.688	0.312
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.688	0.312
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.685	0.314
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.685	0.314
O32 Maternal care for known or suspected malpresentation of foetus	0.684	0.316
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.684	0.316
I30 Acute pericarditis	0.684	0.316
M89 Other disorders of bone	0.683	0.317
G20-G26 Extrapyramidal and movement disorders	0.683	0.317
J44.8 Other specified chronic obstructive pulmonary disease	0.683	0.317
S70-S79 Injuries to the hip and thigh	0.682	0.317
I51.9 Heart disease, unspecified	0.682	0.317
O35 Maternal care for known or suspected foetal abnormality and damage	0.682	0.318
M25.2 Flail joint	0.682	0.318
M25.1 Fistula of joint	0.682	0.318
I51.4 Myocarditis, unspecified	0.681	0.319
O30 Multiple gestation	0.681	0.319
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.680	0.320
E87.6 Hypokalaemia	0.679	0.321
D55-D59 Haemolytic anaemias	0.678	0.322
W20-W49 Exposure to inanimate mechanical forces	0.678	0.322
G30 Alzheimer's disease	0.678	0.322
T85 Complications of other internal prosthetic devices, implants and grafts	0.677	0.323
M23.3 Other meniscus derangements	0.677	0.323
M25.6 Stiffness of joint, not elsewhere classified	0.676	0.324
Q80-Q89 Other congenital malformations	0.676	0.324
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.675	0.325
E83 Disorders of mineral metabolism	0.675	0.325
B44.1 Other pulmonary aspergillosis	0.675	0.325
G47.8 Other sleep disorders	0.674	0.326
G47.4 Narcolepsy and cataplexy	0.674	0.326
G47.2 Disorders of the sleep-wake schedule	0.674	0.326
G47.1 Disorders of excessive somnolence [hypersomnias]	0.674	0.326
Y83.5 Amputation of limb(s)	0.673	0.327
M54 Dorsalgia	0.673	0.327
S82.10 Fracture of upper end of tibia (closed)	0.673	0.327
T79-T79 Certain early complications of trauma	0.672	0.327
Y83.0 Surgical operation with transplant of whole organ	0.672	0.328
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.671	0.329
B48 Other mycoses, not elsewhere classified	0.670	0.330
B47 Mycetoma	0.670	0.330
B46 Zygomycosis	0.670	0.330
B45 Cryptococcosis	0.670	0.330
B43 Chromomycosis and phaeomycotic abscess	0.670	0.330
B42 Sporotrichosis	0.670	0.330
B41 Paracoccidioidomycosis	0.670	0.330
B40 Blastomycosis	0.670	0.330
B39 Histoplasmosis	0.670	0.330
B38 Coccidioidomycosis	0.670	0.330
B36 Other superficial mycoses	0.670	0.330
B49 Unspecified mycosis	0.670	0.330
Q20-Q28 Congenital malformations of the circulatory system	0.670	0.330
R26.8 Other and unspecified abnormalities of gait and mobility	0.669	0.331
L91 Hypertrophic disorders of skin	0.669	0.331
I08.8 Other multiple valve diseases	0.669	0.331
O72 Postpartum haemorrhage	0.667	0.333
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.666	0.334
Y40 Systemic antibiotics	0.666	0.334
S82.3 Fracture of lower end of tibia	0.665	0.335
J13 Pneumonia due to Streptococcus pneumoniae	0.665	0.335
R25.3 Fasciculation	0.665	0.335
M24.9 Joint derangement, unspecified	0.665	0.335
M24.7 Protrusio acetabuli	0.665	0.335
M24.6 Ankylosis of joint	0.665	0.335
M24.5 Contracture of joint	0.665	0.335
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.665	0.335
G81.9 Hemiplegia, unspecified	0.665	0.335
S92.4 Fracture of great toe	0.664	0.336
I47.9 Paroxysmal tachycardia, unspecified	0.664	0.336
M51.9 Intervertebral disk disorder, unspecified	0.663	0.336
I46 Cardiac arrest	0.663	0.336
E27 Other disorders of adrenal gland	0.663	0.337
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.663	0.337
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.663	0.337
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.663	0.337
E87.4 Mixed disorder of acid-base balance	0.662	0.337
O45 Premature separation of placenta [abruptio placentae]	0.662	0.337
O33 Maternal care for known or suspected disproportion	0.662	0.337
O31 Complications specific to multiple gestation	0.662	0.337
M24.16 Other articular cartilage disorders (Lower leg)	0.660	0.340
O80-O84 Delivery	0.659	0.341
S40-S49 Injuries to the shoulder and upper arm	0.659	0.341
S08 Traumatic amputation of part of head	0.659	0.341
S07 Crushing injury of head	0.659	0.341
S04 Injury of cranial nerves	0.659	0.341
S03 Dislocation, sprain and strain of joints and ligaments of head	0.659	0.341
I07 Rheumatic tricuspid valve diseases	0.659	0.341
O43 Placental disorders	0.658	0.342
B35 Dermatophytosis	0.657	0.343
J17 Pneumonia in diseases classified elsewhere	0.657	0.343
I49.5 Sick sinus syndrome	0.656	0.344
Y83.4 Other reconstructive surgery	0.655	0.345
M24.27 Disorder of ligament (Ankle and foot)	0.654	0.346
B50 Plasmodium falciparum malaria	0.654	0.346
S00.1 Contusion of eyelid and periocular area	0.653	0.347
A08 Viral and other specified intestinal infections	0.652	0.347
L85 Other epidermal thickening	0.652	0.348
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.652	0.348
T93.9 Sequelae of unspecified injury of lower limb	0.652	0.348
G50-G59 Nerve, nerve root and plexus disorders	0.652	0.348
S88 Traumatic amputation of lower leg	0.651	0.349
S87 Crushing injury of lower leg	0.651	0.349
S86 Injury of muscle and tendon at lower leg level	0.651	0.349
S85 Injury of blood vessels at lower leg level	0.651	0.349
S84 Injury of nerves at lower leg level	0.651	0.349
O75 Other complications of labour and delivery, not elsewhere classified	0.651	0.349
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.651	0.349
L60.0 Ingrowing nail	0.651	0.349
O73 Retained placenta and membranes, without haemorrhage	0.651	0.349
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.651	0.349
M86 Osteomyelitis	0.651	0.349
I09 Other rheumatic heart diseases	0.650	0.350
I06 Rheumatic aortic valve diseases	0.650	0.350
B37.0 Candidal stomatitis	0.649	0.351
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.648	0.352
S82.2 Fracture of shaft of tibia	0.648	0.352
T66-T78 Other and unspecified effects of external causes	0.648	0.352
M84.03 Malunion of fracture (Forearm)	0.648	0.352
S82.4 Fracture of fibula alone	0.648	0.352
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.648	0.352
E87.1 Hypo-osmolality and hyponatraemia	0.647	0.353
Y84.2 Radiological procedure and radiotherapy	0.647	0.353

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations