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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118006904
log Bayes Factor = 18.7559
Chromosome 14   position 40,477,467  (GRCh37) Explore rs118006904 on Ensembl!
Variant rs118006904 is part of Cluster X0070

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
H25-H28 Disorders of lens
0.993 0.007 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.991 0.009 0.000
Chapter V Mental and behavioural disorders
0.987 0.013 0.000
H25 Senile cataract
0.986 0.014 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.986 0.014 0.000
E10-E14 Diabetes mellitus
0.977 0.023 0.000
Chapter II Neoplasms
0.976 0.024 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.974 0.026 0.000
H25.1 Senile nuclear cataract
0.970 0.030 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.970 0.030 0.000
K22 Other diseases of oesophagus
0.968 0.032 0.000
K70-K77 Diseases of liver
0.967 0.033 0.000
R11 Nausea and vomiting
0.966 0.034 0.000
K50-K52 Noninfective enteritis and colitis
0.963 0.037 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.959 0.041 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.953 0.047 0.000
K76 Other diseases of liver
0.944 0.056 0.000
Chapter I Certain infectious and parasitic diseases
0.943 0.057 0.000
K51 Ulcerative colitis
0.938 0.062 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.938 0.062 0.000
H02 Other disorders of eyelid
0.935 0.065 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.934 0.066 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.934 0.066 0.000
E14 Unspecified diabetes mellitus
0.933 0.067 0.000
K90-K93 Other diseases of the digestive system
0.932 0.068 0.000
F30-F39 Mood [affective] disorders
0.930 0.070 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.930 0.070 0.000
H25.8 Other senile cataract
0.930 0.070 0.000
D60-D64 Aplastic and other anaemias
0.929 0.071 0.000
K26 Duodenal ulcer
0.928 0.072 0.000
C51-C58 Malignant neoplasms of female genital organs
0.926 0.074 0.000
K22.9 Disease of oesophagus, unspecified
0.924 0.076 0.000
E11 Non-insulin-dependent diabetes mellitus
0.920 0.080 0.000
K83 Other diseases of biliary tract
0.920 0.080 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.919 0.081 0.000
A30-A49 Other bacterial diseases
0.916 0.084 0.000
D70 Agranulocytosis
0.912 0.088 0.000
W00-W19 Falls
0.912 0.088 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.911 0.089 0.000
H02.3 Blepharochalasis
0.906 0.094 0.000
K21 Gastro-oesophageal reflux disease
0.902 0.098 0.000
E14.9 Without complications
0.901 0.099 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.900 0.100 0.000
K92 Other diseases of digestive system
0.899 0.101 0.000
J42 Unspecified chronic bronchitis
0.897 0.103 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.897 0.103 0.000
K22.1 Ulcer of oesophagus
0.892 0.108 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.892 0.108 0.000
K25 Gastric ulcer
0.890 0.110 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.889 0.111 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.889 0.111 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.885 0.115 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.884 0.116 0.000
R15 Faecal incontinence
0.882 0.118 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.880 0.120 0.000
E11.9 Without complications
0.880 0.120 0.000
Chapter XIV Diseases of the genitourinary system
0.879 0.121 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.879 0.121 0.000
A41 Other septicaemia
0.872 0.128 0.000
E00-E07 Disorders of thyroid gland
0.864 0.136 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.862 0.138 0.000
H02.8 Other specified disorders of eyelid
0.861 0.139 0.000
R12 Heartburn
0.860 0.140 0.000
K65-K67 Diseases of peritoneum
0.860 0.140 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.854 0.146 0.000
K92.0 Haematemesis
0.853 0.147 0.000
C54 Malignant neoplasm of corpus uteri
0.852 0.148 0.000
H30-H36 Disorders of choroid and retina
0.851 0.149 0.000
M50-M54 Other dorsopathies
0.850 0.150 0.000
F32 Depressive episode
0.850 0.150 0.000
R18 Ascites
0.849 0.151 0.000
N17-N19 Renal failure
0.848 0.152 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.842 0.158 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.839 0.161 0.000
J40 Bronchitis, not specified as acute or chronic
0.838 0.162 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.835 0.165 0.000
K31 Other diseases of stomach and duodenum
0.834 0.166 0.000
K50 Crohn's disease [regional enteritis]
0.834 0.166 0.000
J09-J18 Influenza and pneumonia
0.834 0.166 0.000
H43-H45 Disorders of vitreous body and globe
0.833 0.167 0.000
J00-J06 Acute upper respiratory infections
0.831 0.169 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.829 0.171 0.000
K35-K38 Diseases of appendix
0.829 0.171 0.000
J95-J99 Other diseases of the respiratory system
0.828 0.171 0.000
E40-E46 Malnutrition
0.827 0.173 0.000
E70-E90 Metabolic disorders
0.826 0.174 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.823 0.177 0.000
V10-V19 Pedal cyclist injured in transport accident
0.822 0.178 0.000
D00-D09 In situ neoplasms
0.821 0.179 0.000
F10.2 Dependence syndrome
0.820 0.180 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.816 0.184 0.000
Chapter IX Diseases of the circulatory system
0.815 0.185 0.000
D68 Other coagulation defects
0.815 0.185 0.000
K80 Cholelithiasis
0.814 0.186 0.000
H33 Retinal detachments and breaks
0.811 0.189 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.810 0.190 0.000
E50-E64 Other nutritional deficiencies
0.806 0.194 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.805 0.195 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.804 0.196 0.000
D64 Other anaemias
0.804 0.196 0.000
A49 Bacterial infection of unspecified site
0.804 0.196 0.000
K85 Acute pancreatitis
0.803 0.197 0.000
K83.1 Obstruction of bile duct
0.802 0.198 0.000
K83.0 Cholangitis
0.800 0.200 0.000
K51.2 Ulcerative (chronic) proctitis
0.800 0.200 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.800 0.200 0.000
C54.1 Endometrium
0.799 0.201 0.000
K51.8 Other ulcerative colitis
0.799 0.201 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.796 0.204 0.000
R47-R49 Symptoms and signs involving speech and voice
0.796 0.204 0.000
C44 Other malignant neoplasms of skin
0.796 0.204 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.796 0.204 0.000
H18 Other disorders of cornea
0.795 0.205 0.000
D80-D89 Certain disorders involving the immune mechanism
0.794 0.206 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.793 0.207 0.000
Chapter XXII Codes for special purposes
0.790 0.210 0.000
H25.9 Senile cataract, unspecified
0.790 0.210 0.000
B35-B49 Mycoses
0.789 0.211 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.788 0.212 0.000
K51.4 Pseudopolyposis of colon
0.787 0.213 0.000
N18 Chronic renal failure
0.787 0.213 0.000
N17 Acute renal failure
0.786 0.214 0.000
S00-S09 Injuries to the head
0.786 0.214 0.000
S60-S69 Injuries to the wrist and hand
0.786 0.214 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.784 0.216 0.000
M80-M85 Disorders of bone density and structure
0.782 0.218 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.782 0.218 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.782 0.218 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.782 0.218 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.782 0.218 0.000
H26 Other cataract
0.781 0.219 0.000
W07 Fall involving chair
0.780 0.220 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.777 0.223 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.777 0.223 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.771 0.229 0.000
F31 Bipolar affective disorder
0.769 0.231 0.000
H53-H54 Visual disturbances and blindness
0.768 0.232 0.000
N99-N99 Other disorders of the genitourinary system
0.767 0.233 0.000
R41.3 Other amnesia
0.766 0.234 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.766 0.234 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.766 0.234 0.000
C15-C26 Malignant neoplasms of digestive organs
0.766 0.234 0.000
D62 Acute posthaemorrhagic anaemia
0.765 0.235 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.764 0.236 0.000
W20-W49 Exposure to inanimate mechanical forces
0.762 0.238 0.000
H55-H59 Other disorders of eye and adnexa
0.761 0.239 0.000
M50 Cervical disk disorders
0.758 0.242 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.754 0.246 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.752 0.248 0.000
H02.4 Ptosis of eyelid
0.751 0.249 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.751 0.249 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.749 0.251 0.000
E87.2 Acidosis
0.749 0.251 0.000
F10.3 Withdrawal state
0.748 0.252 0.000
R21 Rash and other nonspecific skin eruption
0.748 0.252 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.748 0.252 0.000
M86-M90 Other osteopathies
0.746 0.253 0.000
K83.8 Other specified diseases of biliary tract
0.745 0.255 0.000
H33.3 Retinal breaks without detachment
0.745 0.255 0.000
K51.5 Mucosal proctocolitis
0.745 0.255 0.000
K75 Other inflammatory liver diseases
0.744 0.256 0.000
R17 Unspecified jaundice
0.744 0.256 0.000
N17.9 Acute renal failure, unspecified
0.743 0.257 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.742 0.258 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.741 0.259 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.739 0.261 0.000
K65 Peritonitis
0.738 0.262 0.000
E11.5 With peripheral circulatory complications
0.737 0.263 0.000
H26.4 After-cataract
0.737 0.263 0.000
V80-V89 Other land transport accidents
0.737 0.263 0.000
C51 Malignant neoplasm of vulva
0.736 0.264 0.000
A41.9 Septicaemia, unspecified
0.736 0.264 0.000
S50-S59 Injuries to the elbow and forearm
0.734 0.266 0.000
D75 Other diseases of blood and blood-forming organs
0.734 0.266 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.734 0.266 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.732 0.268 0.000
Y86 Sequelae of other accidents
0.730 0.270 0.000
A80-A89 Viral infections of the central nervous system
0.730 0.270 0.000
I27 Other pulmonary heart diseases
0.729 0.271 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.729 0.271 0.000
C44.4 Skin of scalp and neck
0.727 0.273 0.000
Y40 Systemic antibiotics
0.727 0.273 0.000
K86 Other diseases of pancreas
0.727 0.273 0.000
H43 Disorders of vitreous body
0.724 0.276 0.000
K35 Acute appendicitis
0.723 0.277 0.000
W18 Other fall on same level
0.723 0.277 0.000
M45-M49 Spondylopathies
0.723 0.277 0.000
C43 Malignant melanoma of skin
0.722 0.278 0.000
C53 Malignant neoplasm of cervix uteri
0.720 0.280 0.000
K25.3 Acute without haemorrhage or perforation
0.720 0.280 0.000
Y83.6 Removal of other organ (partial) (total)
0.719 0.281 0.000
O00-O08 Pregnancy with abortive outcome
0.719 0.281 0.000
D50-D53 Nutritional anaemias
0.718 0.282 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H10-H13 Disorders of conjunctiva
0.717 0.283 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.283 0.000
F33 Recurrent depressive disorder
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X60-X84 Intentional self-harm
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
F10.0 Acute intoxication
0.715 0.285 0.000
D55-D59 Haemolytic anaemias
0.714 0.286 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.714 0.286 0.000
Y43 Primarily systemic agents
0.714 0.286 0.000
D64.9 Anaemia, unspecified
0.714 0.286 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.287 0.000
K76.8 Other specified diseases of liver
0.712 0.287 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.712 0.288 0.000
H27 Other disorders of lens
0.712 0.288 0.000
R41.2 Retrograde amnesia
0.712 0.288 0.000
Y42.5 Other oestrogens and progestogens
0.712 0.288 0.000
F32.9 Depressive episode, unspecified
0.711 0.289 0.000
K28 Gastrojejunal ulcer
0.710 0.289 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.710 0.289 0.000
Y42.7 Androgens and anabolic congeners
0.710 0.290 0.000
E20-E35 Disorders of other endocrine glands
0.709 0.291 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.709 0.291 0.000
M65-M68 Disorders of synovium and tendon
0.709 0.291 0.000
W13 Fall from, out of or through building or structure
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.708 0.292 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.707 0.292 0.000
F70-F79 Mental retardation
0.707 0.292 0.000
F60-F69 Disorders of adult personality and behaviour
0.707 0.292 0.000
H25.2 Senile cataract, morgagnian type
0.707 0.293 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.707 0.293 0.000
E46 Unspecified protein-energy malnutrition
0.707 0.293 0.000
D73 Diseases of spleen
0.707 0.293 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.706 0.294 0.000
F99-F99 Unspecified mental disorder
0.706 0.294 0.000
K31.8 Other specified diseases of stomach and duodenum
0.706 0.294 0.000
D04 Carcinoma in situ of skin
0.705 0.295 0.000
W19 Unspecified fall
0.705 0.295 0.000
C25 Malignant neoplasm of pancreas
0.704 0.296 0.000
K22.5 Diverticulum of oesophagus, acquired
0.704 0.296 0.000
K51.9 Ulcerative colitis, unspecified
0.704 0.296 0.000
K26.7 Chronic without haemorrhage or perforation
0.703 0.297 0.000
S90-S99 Injuries to the ankle and foot
0.703 0.297 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.702 0.298 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.702 0.298 0.000
M70-M79 Other soft tissue disorders
0.702 0.298 0.000
K22.4 Dyskinesia of oesophagus
0.701 0.298 0.000
E13 Other specified diabetes mellitus
0.701 0.299 0.000
E12 Malnutrition-related diabetes mellitus
0.701 0.299 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.700 0.300 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.700 0.300 0.000
C44.2 Skin of ear and external auricular canal
0.699 0.301 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.699 0.301 0.000
K22.0 Achalasia of cardia
0.698 0.301 0.000
H33.0 Retinal detachment with retinal break
0.697 0.303 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.695 0.305 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.695 0.305 0.000
D61 Other aplastic anaemias
0.694 0.305 0.000
K22.3 Perforation of oesophagus
0.694 0.306 0.000
K77 Liver disorders in diseases classified elsewhere
0.694 0.306 0.000
K73 Chronic hepatitis, not elsewhere classified
0.694 0.306 0.000
K71 Toxic liver disease
0.694 0.306 0.000
S70-S79 Injuries to the hip and thigh
0.694 0.306 0.000
K04 Diseases of pulp and periapical tissues
0.693 0.307 0.000
D68.8 Other specified coagulation defects
0.692 0.308 0.000
K70 Alcoholic liver disease
0.691 0.309 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.691 0.309 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.691 0.309 0.000
K01 Embedded and impacted teeth
0.691 0.309 0.000
F10.4 Withdrawal state with delirium
0.689 0.311 0.000
S40-S49 Injuries to the shoulder and upper arm
0.689 0.311 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.688 0.312 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.688 0.312 0.000
K22.7 Barrett's oesophagus
0.688 0.312 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.687 0.312 0.000
H05 Disorders of orbit
0.687 0.312 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.687 0.312 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.687 0.313 0.000
H04 Disorders of lachrymal system
0.687 0.313 0.000
D68.9 Coagulation defect, unspecified
0.687 0.313 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.687 0.313 0.000
Y52 Agents primarily affecting the cardiovascular system
0.686 0.314 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.686 0.314 0.000
J60-J70 Lung diseases due to external agents
0.686 0.314 0.000
S62 Fracture at wrist and hand level
0.685 0.315 0.000
W07.9 Unspecified place
0.685 0.315 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.684 0.316 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.683 0.316 0.000
D74 Methaemoglobinaemia
0.683 0.316 0.000
D72 Other disorders of white blood cells
0.683 0.316 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.683 0.316 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.683 0.316 0.000
R80 Isolated proteinuria
0.683 0.317 0.000
J46 Status asthmaticus
0.683 0.317 0.000
K50.9 Crohn's disease, unspecified
0.682 0.318 0.000
K92.1 Melaena
0.681 0.319 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.680 0.319 0.000
K72 Hepatic failure, not elsewhere classified
0.680 0.320 0.000
S02 Fracture of skull and facial bones
0.679 0.321 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.679 0.321 0.000
A49.8 Other bacterial infections of unspecified site
0.678 0.322 0.000
K76.7 Hepatorenal syndrome
0.677 0.323 0.000
K76.5 Hepatic veno-occlusive disease
0.677 0.323 0.000
K76.4 Peliosis hepatis
0.677 0.323 0.000
K76.3 Infarction of liver
0.677 0.323 0.000
K76.2 Central haemorrhagic necrosis of liver
0.677 0.323 0.000
K76.1 Chronic passive congestion of liver
0.677 0.323 0.000
K26.4 Chronic or unspecified with haemorrhage
0.676 0.324 0.000
N18.4 Chronic kidney disease, stage 4
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.676 0.324 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.676 0.324 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.676 0.324 0.000
B65-B83 Helminthiases
0.676 0.324 0.000
B50-B64 Protozoal diseases
0.676 0.324 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.676 0.324 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.676 0.324 0.000
A75-A79 Rickettsioses
0.676 0.324 0.000
A70-A74 Other diseases caused by chlamydiae
0.676 0.324 0.000
A65-A69 Other spirochaetal diseases
0.676 0.324 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.676 0.324 0.000
A20-A28 Certain zoonotic bacterial diseases
0.676 0.324 0.000
A15-A19 Tuberculosis
0.676 0.324 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.674 0.325 0.000
C44.6 Skin of upper limb, including shoulder
0.674 0.326 0.000
E11.3 With ophthalmic complications
0.673 0.327 0.000
M54 Dorsalgia
0.673 0.327 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.672 0.327 0.000
H20 Iridocyclitis
0.672 0.328 0.000
K50.8 Other Crohn's disease
0.671 0.329 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.671 0.329 0.000
H02.6 Xanthelasma of eyelid
0.671 0.329 0.000
H02.2 Lagophthalmos
0.671 0.329 0.000
K31.7 Polyp of stomach and duodenum
0.671 0.329 0.000
N10-N16 Renal tubulo-interstitial diseases
0.671 0.329 0.000
I27.2 Other secondary pulmonary hypertension
0.670 0.330 0.000
Y59 Other and unspecified vaccines and biological substances
0.670 0.330 0.000
Y58 Bacterial vaccines
0.670 0.330 0.000
Y57 Other and unspecified drugs and medicaments
0.670 0.330 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.670 0.330 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.670 0.330 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.670 0.330 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.670 0.330 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.670 0.330 0.000
Y48 Anaesthetics and therapeutic gases
0.670 0.330 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.670 0.330 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.670 0.330 0.000
Y44 Agents primarily affecting blood constituents
0.670 0.330 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
M91-M94 Chondropathies
0.670 0.330 0.000
M60-M63 Disorders of muscles
0.670 0.330 0.000
M00-M03 Infectious arthropathies
0.670 0.330 0.000
K76.6 Portal hypertension
0.670 0.330 0.000
D86 Sarcoidosis
0.669 0.331 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.669 0.331 0.000
E14.8 With unspecified complications
0.669 0.331 0.000
E14.7 With multiple complications
0.669 0.331 0.000
E14.6 With other specified complications
0.669 0.331 0.000
E14.5 With peripheral circulatory complications
0.669 0.331 0.000
E14.4 With neurological complications
0.669 0.331 0.000
E14.2 Withrenal complications
0.669 0.331 0.000
E14.1 With ketoacidosis
0.669 0.331 0.000
E14.0 With coma
0.669 0.331 0.000
J98 Other respiratory disorders
0.668 0.332 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.668 0.332 0.000
K27 Peptic ulcer, site unspecified
0.667 0.333 0.000
Y95 Nosocomial condition
0.667 0.333 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.667 0.333 0.000
F38 Other mood [affective] disorders
0.667 0.333 0.000
F34 Persistent mood [affective] disorders
0.667 0.333 0.000
F30 Manic episode
0.667 0.333 0.000
F39 Unspecified mood [affective] disorder
0.667 0.333 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.667 0.333 0.000
E07 Other disorders of thyroid
0.667 0.333 0.000
R45 Symptoms and signs involving emotional state
0.667 0.333 0.000
E14.3 With ophthalmic complications
0.666 0.333 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.666 0.333 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.666 0.334 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.666 0.334 0.000
K85.1 Biliary acute pancreatitis
0.665 0.334 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.665 0.335 0.000
K26.5 Chronic or unspecified with perforation
0.665 0.335 0.000
K26.2 Acute with both haemorrhage and perforation
0.665 0.335 0.000
K26.1 Acute with perforation
0.665 0.335 0.000
K26.0 Acute with haemorrhage
0.665 0.335 0.000
Y83.8 Other surgical procedures
0.665 0.335 0.000
K35.9 Acute appendicitis, unspecified
0.665 0.335 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.664 0.336 0.000
C58 Malignant neoplasm of placenta
0.664 0.336 0.000
C52 Malignant neoplasm of vagina
0.664 0.336 0.000
H01 Other inflammation of eyelid
0.663 0.337 0.000
B37 Candidiasis
0.663 0.337 0.000
N25-N29 Other disorders of kidney and ureter
0.662 0.338 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.662 0.338 0.000
R40 Somnolence, stupor and coma
0.662 0.338 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.662 0.338 0.000
K40-K46 Hernia
0.661 0.339 0.000
E04 Other non-toxic goitre
0.661 0.339 0.000
S00 Superficial injury of head
0.661 0.339 0.000
K66 Other disorders of peritoneum
0.661 0.339 0.000
I60-I69 Cerebrovascular diseases
0.660 0.340 0.000
H16 Keratitis
0.660 0.340 0.000
E11.8 With unspecified complications
0.660 0.340 0.000
E11.7 With multiple complications
0.660 0.340 0.000
E11.6 With other specified complications
0.660 0.340 0.000
E11.1 With ketoacidosis
0.660 0.340 0.000
E11.0 With coma
0.660 0.340 0.000
R47 Speech disturbances, not elsewhere classified
0.660 0.340 0.000
K83.9 Disease of biliary tract, unspecified
0.659 0.341 0.000
K83.5 Biliary cyst
0.659 0.341 0.000
K83.4 Spasm of sphincter of Oddi
0.659 0.341 0.000
K83.3 Fistula of bile duct
0.659 0.341 0.000
K83.2 Perforation of bile duct
0.659 0.341 0.000
A00-A09 Intestinal infectious diseases
0.659 0.341 0.000
A41.8 Other specified septicaemia
0.659 0.341 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.659 0.341 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.659 0.341 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.659 0.341 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.659 0.341 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.659 0.341 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.659 0.341 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.659 0.341 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.659 0.341 0.000
F11 Mental and behavioural disorders due to use of opioids
0.659 0.341 0.000
B15-B19 Viral hepatitis
0.658 0.342 0.000
E87.0 Hyperosmolality and hypernatraemia
0.658 0.342 0.000
H18.5 Hereditary corneal dystrophies
0.658 0.342 0.000
A49.0 Staphylococcal infection, unspecified
0.657 0.342 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.657 0.343 0.000
A48 Other bacterial diseases, not elsewhere classified
0.657 0.343 0.000
A44 Bartonellosis
0.657 0.343 0.000
A43 Nocardiosis
0.657 0.343 0.000
A42 Actinomycosis
0.657 0.343 0.000
A40 Streptococcal septicaemia
0.657 0.343 0.000
A39 Meningococcal infection
0.657 0.343 0.000
A37 Whooping cough
0.657 0.343 0.000
A36 Diphtheria
0.657 0.343 0.000
A32 Listeriosis
0.657 0.343 0.000
A31 Infection due to other mycobacteria
0.657 0.343 0.000
A30 Leprosy [Hansen's disease]
0.657 0.343 0.000
A46 Erysipelas
0.657 0.343 0.000
A38 Scarlet fever
0.657 0.343 0.000
A35 Other tetanus
0.657 0.343 0.000
A34 Obstetrical tetanus
0.657 0.343 0.000
A33 Tetanus neonatorum
0.657 0.343 0.000
I05-I09 Chronic rheumatic heart diseases
0.655 0.345 0.000
R16.1 Splenomegaly, not elsewhere classified
0.654 0.345 0.000
B25-B34 Other viral diseases
0.654 0.346 0.000
W17 Other fall from one level to another
0.654 0.346 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.654 0.346 0.000
W15 Fall from cliff
0.654 0.346 0.000
W14 Fall from tree
0.654 0.346 0.000
W12 Fall on and from scaffolding
0.654 0.346 0.000
W11 Fall on and from ladder
0.654 0.346 0.000
W10 Fall on and from stairs and steps
0.654 0.346 0.000
W09 Fall involving playground equipment
0.654 0.346 0.000
W08 Fall involving other furniture
0.654 0.346 0.000
W06 Fall involving bed
0.654 0.346 0.000
W05 Fall involving wheelchair
0.654 0.346 0.000
W04 Fall while being carried or supported by other persons
0.654 0.346 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.654 0.346 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.654 0.346 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.654 0.346 0.000
W00 Fall on same level involving ice and snow
0.654 0.346 0.000
K14 Diseases of tongue
0.654 0.346 0.000
F31.9 Bipolar affective disorder, unspecified
0.654 0.346 0.000
R46 Symptoms and signs involving appearance and behaviour
0.653 0.347 0.000
R43 Disturbances of smell and taste
0.653 0.347 0.000
J18 Pneumonia, organism unspecified
0.652 0.348 0.000
K11 Diseases of salivary glands
0.652 0.348 0.000
T66-T78 Other and unspecified effects of external causes
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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