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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118009375
log Bayes Factor = 15.4206
Chromosome 19   position 51,406,426  (GRCh37) Explore rs118009375 on Ensembl!
Variant rs118009375 is part of Cluster X0043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Z80 Family history of malignant neoplasm
0.996 0.004 0.000
Z92 Personal history of medical treatment
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
I25 Chronic ischaemic heart disease
0.987 0.013 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.983 0.017 0.000
I21 Acute myocardial infarction
0.981 0.019 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.981 0.019 0.000
I60-I69 Cerebrovascular diseases
0.980 0.020 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.976 0.024 0.000
I25.2 Old myocardial infarction
0.970 0.030 0.000
I21.9 Acute myocardial infarction, unspecified
0.968 0.032 0.000
Chapter VI Diseases of the nervous system
0.964 0.036 0.000
Chapter I Certain infectious and parasitic diseases
0.964 0.036 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.959 0.041 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.958 0.042 0.000
Chapter II Neoplasms
0.954 0.046 0.000
Z92.3 Personal history of irradiation
0.951 0.049 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.950 0.050 0.000
Z80.3 Family history of malignant neoplasm of breast
0.949 0.051 0.000
M15-M19 Arthrosis
0.946 0.054 0.000
Z98 Other postsurgical states
0.945 0.055 0.000
Z72 Problems related to lifestyle
0.941 0.059 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.932 0.068 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.929 0.071 0.000
I67 Other cerebrovascular diseases
0.926 0.074 0.000
M16 Coxarthrosis [arthrosis of hip]
0.924 0.076 0.000
M80-M85 Disorders of bone density and structure
0.924 0.076 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.918 0.082 0.000
M16.9 Coxarthrosis, unspecified
0.918 0.082 0.000
I60 Subarachnoid haemorrhage
0.916 0.084 0.000
B95-B98 Bacterial, viral and other infectious agents
0.915 0.085 0.000
W00-W19 Falls
0.912 0.088 0.000
Z93 Artificial opening status
0.911 0.089 0.000
S50-S59 Injuries to the elbow and forearm
0.910 0.090 0.000
Chapter VIII Diseases of the ear and mastoid process
0.909 0.091 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.905 0.095 0.000
Z72.1 Alcohol use
0.904 0.096 0.000
I05-I09 Chronic rheumatic heart diseases
0.904 0.096 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.902 0.098 0.000
I24 Other acute ischaemic heart diseases
0.893 0.107 0.000
Z98.0 Intestinal bypass and anastomosis status
0.892 0.108 0.000
Z95.1 Presence of aortocoronary bypass graft
0.891 0.109 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.884 0.116 0.000
S70-S79 Injuries to the hip and thigh
0.882 0.118 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.876 0.124 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.876 0.124 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.875 0.125 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.874 0.126 0.000
C79 Secondary malignant neoplasm of other sites
0.874 0.126 0.000
W20-W49 Exposure to inanimate mechanical forces
0.874 0.126 0.000
I67.9 Cerebrovascular disease, unspecified
0.866 0.134 0.000
M65-M68 Disorders of synovium and tendon
0.862 0.138 0.000
I25.1 Atherosclerotic heart disease
0.862 0.138 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.859 0.141 0.000
M40-M43 Deforming dorsopathies
0.859 0.141 0.000
Z91.5 Personal history of self-harm
0.859 0.141 0.000
W19 Unspecified fall
0.854 0.146 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.853 0.147 0.000
C15-C26 Malignant neoplasms of digestive organs
0.852 0.148 0.000
I30-I52 Other forms of heart disease
0.852 0.148 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.852 0.148 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.845 0.155 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.843 0.157 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.842 0.158 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.840 0.160 0.000
I77 Other disorders of arteries and arterioles
0.840 0.160 0.000
H90-H95 Other disorders of ear
0.839 0.161 0.000
I21.4 Acute subendocardial myocardial infarction
0.837 0.163 0.000
I08 Multiple valve diseases
0.835 0.164 0.000
Z97 Presence of other devices
0.835 0.165 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.833 0.167 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.831 0.168 0.000
M19 Other arthrosis
0.830 0.170 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.829 0.171 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.827 0.173 0.000
M05-M14 Inflammatory polyarthropathies
0.825 0.175 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.824 0.176 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.823 0.177 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.823 0.177 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.822 0.178 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.820 0.180 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.818 0.182 0.000
Z81 Family history of mental and behavioural disorders
0.811 0.188 0.000
M84 Disorders of continuity of bone
0.810 0.190 0.000
M81 Osteoporosis without pathological fracture
0.809 0.191 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.808 0.192 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.807 0.193 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.806 0.194 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.806 0.194 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.802 0.198 0.000
Chapter XXII Codes for special purposes
0.802 0.198 0.000
Z74 Problems related to care-provider dependency
0.800 0.200 0.000
Z87 Personal history of other diseases and conditions
0.798 0.202 0.000
Z93.5 Cystostomy status
0.797 0.203 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.795 0.205 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.794 0.206 0.000
Chapter XIV Diseases of the genitourinary system
0.793 0.207 0.000
A30-A49 Other bacterial diseases
0.792 0.208 0.000
I20 Angina pectoris
0.791 0.209 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.790 0.210 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.788 0.212 0.000
T92 Sequelae of injuries of upper limb
0.787 0.213 0.000
S60-S69 Injuries to the wrist and hand
0.787 0.213 0.000
I77.1 Stricture of artery
0.784 0.216 0.000
S52 Fracture of forearm
0.783 0.217 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.781 0.219 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.780 0.220 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.780 0.220 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.780 0.220 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.777 0.223 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.776 0.224 0.000
I61 Intracerebral haemorrhage
0.775 0.224 0.000
I47 Paroxysmal tachycardia
0.772 0.228 0.000
S10-S19 Injuries to the neck
0.771 0.228 0.000
W19.2 School, other institution and public administrative area
0.771 0.229 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.769 0.231 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.769 0.231 0.000
T86 Failure and rejection of transplanted organs and tissues
0.766 0.234 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.766 0.234 0.000
M43 Other deforming dorsopathies
0.766 0.234 0.000
S50 Superficial injury of forearm
0.763 0.237 0.000
H60-H62 Diseases of external ear
0.762 0.238 0.000
C50-C50 Malignant neoplasm of breast
0.762 0.238 0.000
C15 Malignant neoplasm of oesophagus
0.761 0.239 0.000
M91-M94 Chondropathies
0.758 0.242 0.000
B35-B49 Mycoses
0.757 0.243 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.756 0.244 0.000
M86-M90 Other osteopathies
0.754 0.246 0.000
S72 Fracture of femur
0.754 0.246 0.000
I67.1 Cerebral aneurysm, nonruptured
0.752 0.248 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.751 0.249 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.750 0.250 0.000
W22 Striking against or struck by other objects
0.748 0.252 0.000
Z98.8 Other specified postsurgical states
0.746 0.254 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.745 0.255 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.740 0.260 0.000
L40-L45 Papulosquamous disorders
0.740 0.260 0.000
I73 Other peripheral vascular diseases
0.739 0.261 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.737 0.263 0.000
S20-S29 Injuries to the thorax
0.737 0.263 0.000
I47.2 Ventricular tachycardia
0.737 0.263 0.000
H91 Other hearing loss
0.735 0.265 0.000
L03 Cellulitis
0.734 0.266 0.000
I08.0 Disorders of both mitral and aortic valves
0.734 0.266 0.000
N10-N16 Renal tubulo-interstitial diseases
0.733 0.267 0.000
N20-N23 Urolithiasis
0.733 0.267 0.000
G35 Multiple sclerosis
0.731 0.269 0.000
C18 Malignant neoplasm of colon
0.731 0.269 0.000
Chapter XI Diseases of the digestive system
0.731 0.269 0.000
Z93.6 Other artificial openings of urinary tract status
0.731 0.269 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.730 0.270 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.729 0.271 0.000
T66-T78 Other and unspecified effects of external causes
0.728 0.271 0.000
M81.9 Osteoporosis, unspecified
0.727 0.273 0.000
Z87.1 Personal history of diseases of the digestive system
0.726 0.274 0.000
G90-G99 Other disorders of the nervous system
0.726 0.274 0.000
Z72.2 Drug use
0.726 0.274 0.000
I51 Complications and ill-defined descriptions of heart disease
0.726 0.274 0.000
G30-G32 Other degenerative diseases of the nervous system
0.724 0.275 0.000
Z72.0 Tobacco use
0.723 0.277 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.723 0.277 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.722 0.278 0.000
C34 Malignant neoplasm of bronchus and lung
0.721 0.279 0.000
Z82.3 Family history of stroke
0.720 0.280 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I62 Other nontraumatic intracranial haemorrhage
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
M65 Synovitis and tenosynovitis
0.716 0.284 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.716 0.284 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.714 0.286 0.000
Z80.6 Family history of leukaemia
0.714 0.286 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.714 0.286 0.000
Z92.9 Personal history of medical treatment, unspecified
0.714 0.286 0.000
Z92.8 Personal history of other medical treatment
0.714 0.286 0.000
Z92.5 Personal history of rehabilitation measures
0.714 0.286 0.000
Y86 Sequelae of other accidents
0.714 0.286 0.000
Z92.0 Personal history of contraception
0.713 0.287 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.712 0.287 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X60-X84 Intentional self-harm
0.712 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V80-V89 Other land transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V20-V29 Motorcycle rider injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
Chapter X Diseases of the respiratory system
0.712 0.288 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.711 0.289 0.000
M60-M63 Disorders of muscles
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.711 0.289 0.000
W19.9 Unspecified place
0.711 0.289 0.000
C79.6 Secondary malignant neoplasm of ovary
0.711 0.289 0.000
S90-S99 Injuries to the ankle and foot
0.709 0.291 0.000
I25.6 Silent myocardial ischaemia
0.708 0.292 0.000
I25.4 Coronary artery aneurysm
0.708 0.292 0.000
I25.3 Aneurysm of heart
0.708 0.292 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.708 0.292 0.000
M67 Other disorders of synovium and tendon
0.708 0.292 0.000
G20-G26 Extrapyramidal and movement disorders
0.708 0.292 0.000
A80-A89 Viral infections of the central nervous system
0.707 0.293 0.000
S40-S49 Injuries to the shoulder and upper arm
0.707 0.293 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.706 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.706 0.294 0.000
Y84.8 Other medical procedures
0.705 0.295 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.703 0.297 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.703 0.297 0.000
T87 Complications peculiar to reattachment and amputation
0.703 0.297 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.703 0.297 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.703 0.297 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.703 0.297 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.703 0.297 0.000
M19.0 Primary arthrosis of other joints
0.702 0.298 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.700 0.300 0.000
Z76 Persons encountering health services in other circumstances
0.700 0.300 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.700 0.300 0.000
M43.1 Spondylolisthesis
0.699 0.301 0.000
S00-S09 Injuries to the head
0.699 0.301 0.000
W44 Foreign body entering into or through eye or natural orifice
0.699 0.301 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.698 0.302 0.000
I22 Subsequent myocardial infarction
0.696 0.304 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.696 0.304 0.000
M70-M79 Other soft tissue disorders
0.695 0.305 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.694 0.306 0.000
Z75 Problems related to medical facilities and other health care
0.694 0.306 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.693 0.307 0.000
Z93.2 Ileostomy status
0.693 0.307 0.000
D41.4 Bladder
0.693 0.307 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.691 0.308 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.691 0.308 0.000
B99-B99 Other infectious diseases
0.691 0.309 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.691 0.309 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.691 0.309 0.000
B65-B83 Helminthiases
0.691 0.309 0.000
B50-B64 Protozoal diseases
0.691 0.309 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.691 0.309 0.000
B15-B19 Viral hepatitis
0.691 0.309 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.691 0.309 0.000
A75-A79 Rickettsioses
0.691 0.309 0.000
A70-A74 Other diseases caused by chlamydiae
0.691 0.309 0.000
A65-A69 Other spirochaetal diseases
0.691 0.309 0.000
A20-A28 Certain zoonotic bacterial diseases
0.691 0.309 0.000
A15-A19 Tuberculosis
0.691 0.309 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.691 0.309 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.690 0.310 0.000
I72 Other aneurysm
0.690 0.310 0.000
B07 Viral warts
0.689 0.311 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.689 0.311 0.000
G70-G73 Diseases of myoneural junction and muscle
0.689 0.311 0.000
M06 Other rheumatoid arthritis
0.689 0.311 0.000
I25.5 Ischaemic cardiomyopathy
0.689 0.311 0.000
G40-G47 Episodic and paroxysmal disorders
0.689 0.311 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.688 0.312 0.000
Z93.3 Colostomy status
0.688 0.312 0.000
N13 Obstructive and reflux uropathy
0.688 0.312 0.000
Y40 Systemic antibiotics
0.687 0.313 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.687 0.313 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.687 0.313 0.000
Z91.7 Personal history of female genital mutilation
0.687 0.313 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.687 0.313 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.687 0.313 0.000
Z91.2 Personal history of poor personal hygiene
0.687 0.313 0.000
S51 Open wound of forearm
0.687 0.313 0.000
I70 Atherosclerosis
0.686 0.314 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.686 0.314 0.000
T90 Sequelae of injuries of head
0.685 0.315 0.000
I67.2 Cerebral atherosclerosis
0.685 0.315 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.684 0.316 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.684 0.316 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.683 0.317 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.683 0.317 0.000
S79 Other and unspecified injuries of hip and thigh
0.682 0.318 0.000
L85 Other epidermal thickening
0.681 0.319 0.000
L10-L14 Bullous disorders
0.681 0.319 0.000
Z83 Family history of other specific disorders
0.681 0.319 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.681 0.319 0.000
M85 Other disorders of bone density and structure
0.680 0.320 0.000
H90 Conductive and sensorineural hearing loss
0.680 0.320 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.680 0.320 0.000
I24.8 Other forms of acute ischaemic heart disease
0.679 0.321 0.000
M15 Polyarthrosis
0.678 0.321 0.000
Z98.1 Arthrodesis status
0.678 0.322 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.677 0.322 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.677 0.323 0.000
S70 Superficial injury of hip and thigh
0.677 0.323 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.677 0.323 0.000
Z81.8 Family history of other mental and behavioural disorders
0.676 0.323 0.000
I74 Arterial embolism and thrombosis
0.676 0.324 0.000
G61 Inflammatory polyneuropathy
0.675 0.325 0.000
Z72.9 Problem related to lifestyle, unspecified
0.675 0.325 0.000
Z72.8 Other problems related to lifestyle
0.675 0.325 0.000
Z72.6 Gambling and betting
0.675 0.325 0.000
Z72.5 High-risk sexual behaviour
0.675 0.325 0.000
Z72.4 Inappropriate diet and eating habits
0.675 0.325 0.000
Z72.3 Lack of physical exercise
0.675 0.325 0.000
Z73 Problems related to life-management difficulty
0.675 0.325 0.000
Z74.0 Reduced mobility
0.674 0.326 0.000
T82.1 Mechanical complication of cardiac electronic device
0.672 0.328 0.000
M19.9 Arthrosis, unspecified
0.671 0.329 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.671 0.329 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.671 0.329 0.000
I69 Sequelae of cerebrovascular disease
0.670 0.330 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.668 0.331 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.668 0.331 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.668 0.331 0.000
T82.3 Mechanical complication of other vascular grafts
0.668 0.331 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.668 0.331 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.668 0.331 0.000
R42 Dizziness and giddiness
0.668 0.332 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.667 0.333 0.000
H80-H83 Diseases of inner ear
0.667 0.333 0.000
A41 Other septicaemia
0.667 0.333 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.667 0.333 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.666 0.334 0.000
Z95.3 Presence of xenogenic heart valve
0.666 0.334 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.666 0.334 0.000
Z93.0 Tracheostomy status
0.665 0.335 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.665 0.335 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.665 0.335 0.000
Q60-Q64 Congenital malformations of the urinary system
0.664 0.336 0.000
I42 Cardiomyopathy
0.664 0.336 0.000
Z91.6 Personal history of other physical trauma
0.664 0.336 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.664 0.336 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.664 0.336 0.000
I67.5 Moyamoya disease
0.664 0.336 0.000
I67.4 Hypertensive encephalopathy
0.664 0.336 0.000
I67.3 Progressive vascular leukoencephalopathy
0.664 0.336 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.664 0.336 0.000
L84 Corns and callosities
0.663 0.337 0.000
M16.7 Other secondary coxarthrosis
0.663 0.337 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.663 0.337 0.000
M16.5 Other posttraumatic coxarthrosis
0.663 0.337 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.663 0.337 0.000
M16.3 Other dysplastic coxarthrosis
0.663 0.337 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.663 0.337 0.000
M83 Adult osteomalacia
0.662 0.338 0.000
M82 Osteoporosis in diseases classified elsewhere
0.662 0.338 0.000
H91.9 Hearing loss, unspecified
0.662 0.338 0.000
V10-V19 Pedal cyclist injured in transport accident
0.661 0.338 0.000
C15.9 Oesophagus, unspecified
0.661 0.339 0.000
D45 Polycythaemia vera
0.661 0.339 0.000
C20 Malignant neoplasm of rectum
0.660 0.340 0.000
B02 Zoster [herpes zoster]
0.660 0.340 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.659 0.341 0.000
N60-N64 Disorders of breast
0.659 0.341 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.658 0.341 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.658 0.342 0.000
L91 Hypertrophic disorders of skin
0.658 0.342 0.000
W22.9 Unspecified place
0.658 0.342 0.000
I71 Aortic aneurysm and dissection
0.658 0.342 0.000
S50.9 Superficial injury of forearm, unspecified
0.658 0.342 0.000
M18 Arthrosis of first carpometacarpal joint
0.657 0.343 0.000
T92.1 Sequelae of fracture of arm
0.657 0.343 0.000
I60.8 Other subarachnoid haemorrhage
0.657 0.343 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.657 0.343 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.657 0.343 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.657 0.343 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.657 0.343 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.657 0.343 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.657 0.343 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.657 0.343 0.000
I73.9 Peripheral vascular disease, unspecified
0.657 0.343 0.000
H92 Otalgia and effusion of ear
0.655 0.344 0.000
L81 Other disorders of pigmentation
0.655 0.345 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.655 0.345 0.000
Chapter VII Diseases of the eye and adnexa
0.655 0.345 0.000
S52.5 Fracture of lower end of radius
0.654 0.346 0.000
W18 Other fall on same level
0.654 0.346 0.000
W17 Other fall from one level to another
0.654 0.346 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.654 0.346 0.000
W15 Fall from cliff
0.654 0.346 0.000
W14 Fall from tree
0.654 0.346 0.000
W13 Fall from, out of or through building or structure
0.654 0.346 0.000
W12 Fall on and from scaffolding
0.654 0.346 0.000
W11 Fall on and from ladder
0.654 0.346 0.000
W10 Fall on and from stairs and steps
0.654 0.346 0.000
W09 Fall involving playground equipment
0.654 0.346 0.000
W08 Fall involving other furniture
0.654 0.346 0.000
W07 Fall involving chair
0.654 0.346 0.000
W06 Fall involving bed
0.654 0.346 0.000
W05 Fall involving wheelchair
0.654 0.346 0.000
W04 Fall while being carried or supported by other persons
0.654 0.346 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.654 0.346 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.654 0.346 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.654 0.346 0.000
W00 Fall on same level involving ice and snow
0.654 0.346 0.000
Y95 Nosocomial condition
0.654 0.346 0.000
H61 Other disorders of external ear
0.653 0.347 0.000
Z93.9 Artificial opening status, unspecified
0.653 0.347 0.000
Z93.8 Other artificial opening status
0.653 0.347 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.653 0.347 0.000
S59 Other and unspecified injuries of forearm
0.653 0.347 0.000
S58 Traumatic amputation of forearm
0.653 0.347 0.000
S57 Crushing injury of forearm
0.653 0.347 0.000
S56 Injury of muscle and tendon at forearm level
0.653 0.347 0.000
S55 Injury of blood vessels at forearm level
0.653 0.347 0.000
S54 Injury of nerves at forearm level
0.653 0.347 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.653 0.347 0.000
I45 Other conduction disorders
0.653 0.347 0.000
L20-L30 Dermatitis and eczema
0.653 0.347 0.000
W19.4 Street and highway
0.652 0.348 0.000
G37 Other demyelinating diseases of central nervous system
0.652 0.348 0.000
I95 Hypotension
0.652 0.348 0.000
I33 Acute and subacute endocarditis
0.652 0.348 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.651 0.349 0.000
L82 Seborrhoeic keratosis
0.651 0.349 0.000
S60 Superficial injury of wrist and hand
0.650 0.350 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.650 0.350 0.000
M80 Osteoporosis with pathological fracture
0.649 0.350 0.000
Y44 Agents primarily affecting blood constituents
0.649 0.351 0.000
N23 Unspecified renal colic
0.649 0.351 0.000
D60-D64 Aplastic and other anaemias
0.649 0.351 0.000
I09 Other rheumatic heart diseases
0.648 0.352 0.000
I06 Rheumatic aortic valve diseases
0.648 0.352 0.000
I05 Rheumatic mitral valve diseases
0.648 0.352 0.000
C34.3 Lower lobe, bronchus or lung
0.647 0.353 0.000
L03.1 Cellulitis of other parts of limb
0.647 0.353 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.647 0.353 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.647 0.353 0.000
I07 Rheumatic tricuspid valve diseases
0.646 0.354 0.000
Z95.0 Presence of cardiac pacemaker
0.646 0.354 0.000
L90 Atrophic disorders of skin
0.646 0.354 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.645 0.354 0.000
I67.8 Other specified cerebrovascular diseases
0.646 0.354 0.000
T17 Foreign body in respiratory tract
0.645 0.354 0.000
Y52 Agents primarily affecting the cardiovascular system
0.645 0.355 0.000
M07 Psoriatic and enteropathic arthropathies
0.645 0.355 0.000
I63 Cerebral infarction
0.645 0.355 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.644 0.356 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.643 0.357 0.000
G83 Other paralytic syndromes
0.642 0.358 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.641 0.358 0.000
L03.2 Cellulitis of face
0.641 0.359 0.000
L89 Decubitus ulcer
0.641 0.359 0.000
Q80-Q89 Other congenital malformations
0.641 0.359 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.640 0.359 0.000
I24.1 Dressler's syndrome
0.640 0.360 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.640 0.360 0.000
M84.0 Malunion of fracture
0.639 0.361 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.638 0.362 0.000
T92.0 Sequelae of open wound of upper limb
0.638 0.362 0.000
C71 Malignant neoplasm of brain
0.637 0.363 0.000
N72 Inflammatory disease of cervix uteri
0.636 0.364 0.000
C80 Malignant neoplasm without specification of site
0.635 0.364 0.000
W29 Contact with other powered hand tools and household machinery
0.635 0.365 0.000
T98 Sequelae of other and unspecified effects of external causes
0.634 0.366 0.000
T95 Sequelae of burns, corrosions and frostbite
0.634 0.366 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.634 0.366 0.000
T91 Sequelae of injuries of neck and trunk
0.634 0.366 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.634 0.366 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.634 0.366 0.000
L50-L54 Urticaria and erythema
0.633 0.366 0.000
I35 Nonrheumatic aortic valve disorders
0.633 0.367 0.000
K50-K52 Noninfective enteritis and colitis
0.633 0.367 0.000
D46 Myelodysplastic syndromes
0.633 0.367 0.000
S78 Traumatic amputation of hip and thigh
0.632 0.368 0.000
S77 Crushing injury of hip and thigh
0.632 0.368 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.632 0.368 0.000
S75 Injury of blood vessels at hip and thigh level
0.632 0.368 0.000
S74 Injury of nerves at hip and thigh level
0.632 0.368 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.632 0.368 0.000
S71 Open wound of hip and thigh
0.632 0.368 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.632 0.368 0.000
I10-I15 Hypertensive diseases
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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