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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118021477
log Bayes Factor = 12.0694
Chromosome 22   position 44,389,518  (GRCh37) Explore rs118021477 on Ensembl!
Variant rs118021477 is part of Cluster X0111

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
S60-S69 Injuries to the wrist and hand
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.994 0.006 0.000
F30-F39 Mood [affective] disorders
0.993 0.007 0.000
G40-G47 Episodic and paroxysmal disorders
0.992 0.008 0.000
E11 Non-insulin-dependent diabetes mellitus
0.991 0.009 0.000
H30-H36 Disorders of choroid and retina
0.988 0.012 0.000
G47 Sleep disorders
0.988 0.012 0.000
E70-E90 Metabolic disorders
0.987 0.013 0.000
F31 Bipolar affective disorder
0.986 0.014 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.986 0.014 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.984 0.016 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.983 0.017 0.000
E10.9 Without complications
0.981 0.019 0.000
E78.0 Pure hypercholesterolaemia
0.980 0.020 0.000
G47.3 Sleep apnoea
0.980 0.020 0.000
S62 Fracture at wrist and hand level
0.980 0.020 0.000
G56 Mononeuropathies of upper limb
0.977 0.023 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.977 0.023 0.000
H35 Other retinal disorders
0.976 0.024 0.000
G56.0 Carpal tunnel syndrome
0.975 0.025 0.000
Chapter I Certain infectious and parasitic diseases
0.963 0.037 0.000
G43 Migraine
0.962 0.038 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.954 0.046 0.000
S68 Traumatic amputation of wrist and hand
0.954 0.046 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.952 0.048 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.943 0.057 0.000
F32 Depressive episode
0.941 0.059 0.000
T66-T78 Other and unspecified effects of external causes
0.941 0.059 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.941 0.059 0.000
G43.9 Migraine, unspecified
0.936 0.064 0.000
Q60-Q64 Congenital malformations of the urinary system
0.936 0.064 0.000
M05-M14 Inflammatory polyarthropathies
0.935 0.065 0.000
S62.6 Fracture of other finger
0.932 0.068 0.000
E10.3 With ophthalmic complications
0.931 0.069 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.930 0.070 0.000
E65-E68 Obesity and other hyperalimentation
0.927 0.073 0.000
M06 Other rheumatoid arthritis
0.926 0.074 0.000
I25 Chronic ischaemic heart disease
0.920 0.080 0.000
M06.9 Rheumatoid arthritis, unspecified
0.918 0.082 0.000
O60-O75 Complications of labour and delivery
0.917 0.083 0.000
H35.0 Background retinopathy and retinal vascular changes
0.917 0.083 0.000
I25.1 Atherosclerotic heart disease
0.917 0.083 0.000
I25.2 Old myocardial infarction
0.915 0.085 0.000
H43-H45 Disorders of vitreous body and globe
0.910 0.090 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.909 0.090 0.000
S62.3 Fracture of other metacarpal bone
0.909 0.091 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.906 0.094 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.905 0.095 0.000
E11.5 With peripheral circulatory complications
0.903 0.097 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.902 0.098 0.000
E10.4 With neurological complications
0.898 0.102 0.000
F32.9 Depressive episode, unspecified
0.897 0.103 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.896 0.104 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.896 0.104 0.000
E11.9 Without complications
0.891 0.109 0.000
H35.4 Peripheral retinal degeneration
0.890 0.110 0.000
S70-S79 Injuries to the hip and thigh
0.888 0.112 0.000
M50-M54 Other dorsopathies
0.886 0.114 0.000
T78 Adverse effects, not elsewhere classified
0.885 0.115 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.881 0.119 0.000
O00-O08 Pregnancy with abortive outcome
0.881 0.119 0.000
E66 Obesity
0.880 0.120 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.879 0.121 0.000
S64 Injury of nerves at wrist and hand level
0.878 0.122 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.873 0.127 0.000
E10.1 With ketoacidosis
0.872 0.128 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.870 0.130 0.000
A00-A09 Intestinal infectious diseases
0.868 0.132 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.866 0.134 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.865 0.135 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.865 0.135 0.000
F31.9 Bipolar affective disorder, unspecified
0.863 0.137 0.000
E11.4 With neurological complications
0.857 0.143 0.000
G58 Other mononeuropathies
0.855 0.145 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.854 0.146 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.850 0.150 0.000
Q61 Cystic kidney disease
0.849 0.151 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.847 0.153 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.845 0.155 0.000
T78.4 Allergy, unspecified
0.844 0.156 0.000
S62.60 Fracture of other finger (closed)
0.844 0.156 0.000
I20-I25 Ischaemic heart diseases
0.843 0.157 0.000
M50 Cervical disk disorders
0.840 0.160 0.000
E66.9 Obesity, unspecified
0.840 0.160 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.839 0.161 0.000
E78.5 Hyperlipidaemia, unspecified
0.837 0.163 0.000
H43 Disorders of vitreous body
0.836 0.164 0.000
S63.6 Sprain and strain of finger(s)
0.836 0.164 0.000
H18 Other disorders of cornea
0.834 0.166 0.000
H36 Retinal disorders in diseases classified elsewhere
0.830 0.170 0.000
S62.61 Fracture of other finger (open)
0.830 0.170 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.828 0.172 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.827 0.173 0.000
Q63 Other congenital malformations of kidney
0.827 0.173 0.000
S72 Fracture of femur
0.826 0.174 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.825 0.175 0.000
Chapter IX Diseases of the circulatory system
0.824 0.176 0.000
T79-T79 Certain early complications of trauma
0.822 0.178 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.821 0.179 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.821 0.179 0.000
B65-B83 Helminthiases
0.821 0.179 0.000
S64.4 Injury of digital nerve of other finger
0.820 0.180 0.000
M50.1 Cervical disk disorder with radiculopathy
0.817 0.183 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.814 0.186 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.814 0.186 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.812 0.188 0.000
S61 Open wound of wrist and hand
0.810 0.190 0.000
H33 Retinal detachments and breaks
0.809 0.191 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.805 0.195 0.000
H53-H54 Visual disturbances and blindness
0.805 0.195 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.802 0.198 0.000
E10.6 With other specified complications
0.801 0.199 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.800 0.200 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.799 0.201 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.798 0.202 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.797 0.203 0.000
H35.5 Hereditary retinal dystrophy
0.796 0.204 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.793 0.207 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.790 0.210 0.000
G47.4 Narcolepsy and cataplexy
0.790 0.210 0.000
E10.2 With renal complications
0.786 0.214 0.000
M65-M68 Disorders of synovium and tendon
0.784 0.216 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.782 0.218 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.782 0.218 0.000
T00-T07 Injuries involving multiple body regions
0.781 0.219 0.000
Q80-Q89 Other congenital malformations
0.779 0.221 0.000
H35.2 Other proliferative retinopathy
0.779 0.221 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.777 0.223 0.000
Q61.3 Polycystic kidney, unspecified
0.775 0.224 0.000
E11.1 With ketoacidosis
0.774 0.226 0.000
O03 Spontaneous abortion
0.774 0.226 0.000
M86-M90 Other osteopathies
0.773 0.227 0.000
O66 Other obstructed labour
0.772 0.228 0.000
H55-H59 Other disorders of eye and adnexa
0.772 0.228 0.000
H43.1 Vitreous haemorrhage
0.772 0.228 0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)
0.771 0.229 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.768 0.232 0.000
G43.8 Other migraine
0.767 0.233 0.000
E10.0 With coma
0.766 0.234 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.766 0.234 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.765 0.235 0.000
E11.6 With other specified complications
0.764 0.236 0.000
H35.6 Retinal haemorrhage
0.762 0.237 0.000
B25-B34 Other viral diseases
0.762 0.238 0.000
F80-F89 Disorders of psychological development
0.762 0.238 0.000
E11.8 With unspecified complications
0.760 0.239 0.000
Q00-Q07 Congenital malformations of the nervous system
0.760 0.240 0.000
T82.3 Mechanical complication of other vascular grafts
0.759 0.241 0.000
Q43 Other congenital malformations of intestine
0.759 0.241 0.000
S60 Superficial injury of wrist and hand
0.759 0.241 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.758 0.242 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.756 0.244 0.000
E11.3 With ophthalmic complications
0.756 0.244 0.000
B35-B49 Mycoses
0.756 0.244 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.755 0.245 0.000
S72.0 Fracture of neck of femur
0.755 0.245 0.000
Q50-Q56 Congenital malformations of genital organs
0.754 0.246 0.000
H21 Other disorders of iris and ciliary body
0.750 0.250 0.000
H18.9 Disorder of cornea, unspecified
0.750 0.250 0.000
E20-E35 Disorders of other endocrine glands
0.749 0.251 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.748 0.252 0.000
E85 Amyloidosis
0.747 0.253 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.745 0.255 0.000
E78.2 Mixed hyperlipidaemia
0.744 0.256 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.743 0.257 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.741 0.259 0.000
F33 Recurrent depressive disorder
0.740 0.260 0.000
M80-M85 Disorders of bone density and structure
0.740 0.260 0.000
O70 Perineal laceration during delivery
0.740 0.260 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.740 0.260 0.000
O03.4 Incomplete, without complication
0.737 0.263 0.000
T68 Hypothermia
0.737 0.263 0.000
H18.6 Keratoconus
0.737 0.263 0.000
E50-E64 Other nutritional deficiencies
0.736 0.264 0.000
E40-E46 Malnutrition
0.735 0.265 0.000
H33.0 Retinal detachment with retinal break
0.735 0.265 0.000
H31 Other disorders of choroid
0.735 0.265 0.000
Q61.2 Polycystic kidney, adult type
0.734 0.266 0.000
E11.2 With renal complications
0.733 0.267 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.732 0.268 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.731 0.269 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.731 0.269 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.730 0.270 0.000
H34 Retinal vascular occlusions
0.729 0.271 0.000
S61.1 Open wound of finger(s) with damage to nail
0.728 0.272 0.000
S63.5 Sprain and strain of wrist
0.728 0.272 0.000
I25.3 Aneurysm of heart
0.728 0.272 0.000
F32.1 Moderate depressive episode
0.726 0.274 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.725 0.275 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.723 0.277 0.000
S62.31 Fracture of other metacarpal bone (open)
0.723 0.277 0.000
Q39 Congenital malformations of oesophagus
0.722 0.277 0.000
Q63.0 Accessory kidney
0.722 0.278 0.000
O02 Other abnormal products of conception
0.722 0.278 0.000
M00-M03 Infectious arthropathies
0.721 0.279 0.000
E78.1 Pure hyperglyceridaemia
0.720 0.280 0.000
B80 Enterobiasis
0.719 0.280 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.719 0.281 0.000
T78.3 Angioneurotic oedema
0.718 0.282 0.000
S65 Injury of blood vessels at wrist and hand level
0.718 0.282 0.000
H36.0 Diabetic retinopathy
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.716 0.284 0.000
O73 Retained placenta and membranes, without haemorrhage
0.715 0.285 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.715 0.285 0.000
T82.1 Mechanical complication of cardiac electronic device
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
E10.5 With peripheral circulatory complications
0.713 0.287 0.000
G47.8 Other sleep disorders
0.713 0.287 0.000
F38 Other mood [affective] disorders
0.712 0.288 0.000
F34 Persistent mood [affective] disorders
0.712 0.288 0.000
F39 Unspecified mood [affective] disorder
0.712 0.288 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.712 0.288 0.000
G58.8 Other specified mononeuropathies
0.712 0.288 0.000
B15-B19 Viral hepatitis
0.712 0.288 0.000
H35.8 Other specified retinal disorders
0.712 0.288 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.711 0.289 0.000
G41 Status epilepticus
0.711 0.289 0.000
E11.7 With multiple complications
0.711 0.289 0.000
E11.0 With coma
0.711 0.289 0.000
E74 Other disorders of carbohydrate metabolism
0.711 0.289 0.000
F30 Manic episode
0.711 0.289 0.000
G47.9 Sleep disorder, unspecified
0.710 0.290 0.000
S62.5 Fracture of thumb
0.710 0.290 0.000
S72.3 Fracture of shaft of femur
0.709 0.291 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.709 0.291 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.709 0.291 0.000
H30 Chorioretinal inflammation
0.709 0.291 0.000
A30-A49 Other bacterial diseases
0.708 0.292 0.000
G47.2 Disorders of the sleep-wake schedule
0.708 0.292 0.000
E84 Cystic fibrosis
0.708 0.292 0.000
E79 Disorders of purine and pyrimidine metabolism
0.708 0.292 0.000
E77 Disorders of glycoprotein metabolism
0.708 0.292 0.000
E76 Disorders of glycosaminoglycan metabolism
0.708 0.292 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.708 0.292 0.000
E72 Other disorders of amino-acid metabolism
0.708 0.292 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.708 0.292 0.000
E70 Disorders of aromatic amino-acid metabolism
0.708 0.292 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.708 0.292 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.707 0.293 0.000
F31.8 Other bipolar affective disorders
0.707 0.293 0.000
F31.7 Bipolar affective disorder, currently in remission
0.707 0.293 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.707 0.293 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.707 0.293 0.000
Q35-Q37 Cleft lip and cleft palate
0.707 0.293 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.707 0.293 0.000
S90-S99 Injuries to the ankle and foot
0.706 0.294 0.000
M06.0 Seronegative rheumatoid arthritis
0.706 0.294 0.000
M11 Other crystal arthropathies
0.706 0.294 0.000
E78.6 Lipoprotein deficiency
0.705 0.294 0.000
E78.4 Other hyperlipidaemia
0.705 0.294 0.000
E78.3 Hyperchylomicronaemia
0.705 0.294 0.000
G52 Disorders of other cranial nerves
0.705 0.295 0.000
O00 Ectopic pregnancy
0.704 0.296 0.000
M91-M94 Chondropathies
0.704 0.296 0.000
S72.00 Fracture of neck of femur (closed)
0.704 0.296 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.704 0.296 0.000
S62.7 Multiple fractures of fingers
0.702 0.298 0.000
S62.4 Multiple fractures of metacarpal bones
0.702 0.298 0.000
S62.1 Fracture of other carpal bone(s)
0.702 0.298 0.000
T85.2 Mechanical complication of intraocular lens
0.702 0.298 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.702 0.298 0.000
H43.9 Disorder of vitreous body, unspecified
0.701 0.299 0.000
H44 Disorders of globe
0.701 0.299 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.700 0.300 0.000
G56.4 Causalgia
0.700 0.300 0.000
G56.3 Lesion of radial nerve
0.700 0.300 0.000
G56.1 Other lesions of median nerve
0.700 0.300 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.700 0.300 0.000
H35.1 Retinopathy of prematurity
0.700 0.300 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.699 0.301 0.000
T86 Failure and rejection of transplanted organs and tissues
0.698 0.301 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.698 0.302 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.698 0.302 0.000
S67 Crushing injury of wrist and hand
0.698 0.302 0.000
H17 Corneal scars and opacities
0.698 0.302 0.000
G58.7 Mononeuritis multiplex
0.697 0.303 0.000
B99-B99 Other infectious diseases
0.697 0.303 0.000
S69 Other and unspecified injuries of wrist and hand
0.695 0.305 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.694 0.306 0.000
A80-A89 Viral infections of the central nervous system
0.694 0.306 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.693 0.307 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.690 0.309 0.000
B50-B64 Protozoal diseases
0.690 0.309 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.690 0.309 0.000
A75-A79 Rickettsioses
0.690 0.309 0.000
A70-A74 Other diseases caused by chlamydiae
0.690 0.309 0.000
A65-A69 Other spirochaetal diseases
0.690 0.309 0.000
A20-A28 Certain zoonotic bacterial diseases
0.690 0.309 0.000
A15-A19 Tuberculosis
0.690 0.309 0.000
H35.9 Retinal disorder, unspecified
0.690 0.310 0.000
S62.2 Fracture of first metacarpal bone
0.690 0.310 0.000
G43.3 Complicated migraine
0.689 0.310 0.000
G43.2 Status migrainosus
0.689 0.310 0.000
G43.0 Migraine without aura [common migraine]
0.689 0.310 0.000
M40-M43 Deforming dorsopathies
0.689 0.311 0.000
O71 Other obstetric trauma
0.688 0.312 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.688 0.312 0.000
T87 Complications peculiar to reattachment and amputation
0.687 0.313 0.000
M14 Arthropathies in other diseases classified elsewhere
0.686 0.314 0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified
0.684 0.316 0.000
S68.8 Traumatic amputation of other parts of wrist and hand
0.684 0.316 0.000
S68.4 Traumatic amputation of hand at wrist level
0.684 0.316 0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand
0.684 0.316 0.000
S68.0 Traumatic amputation of thumb (complete)(partial)
0.684 0.316 0.000
E23 Hypofunction and other disorders of pituitary gland
0.683 0.317 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.682 0.318 0.000
I25.4 Coronary artery aneurysm
0.682 0.318 0.000
G70-G73 Diseases of myoneural junction and muscle
0.682 0.318 0.000
E89.0 Postprocedural hypothyroidism
0.682 0.318 0.000
G56.8 Other mononeuropathies of upper limb
0.679 0.321 0.000
H35.3 Degeneration of macula and posterior pole
0.678 0.322 0.000
O85-O92 Complications predominantly related to the puerperium
0.676 0.324 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.676 0.324 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.676 0.324 0.000
H16 Keratitis
0.676 0.324 0.000
F32.8 Other depressive episodes
0.675 0.325 0.000
E66.8 Other obesity
0.675 0.325 0.000
T75 Effects of other external causes
0.674 0.326 0.000
T74 Maltreatment syndromes
0.674 0.326 0.000
T73 Effects of other deprivation
0.674 0.326 0.000
T70 Effects of air pressure and water pressure
0.674 0.326 0.000
T69 Other effects of reduced temperature
0.674 0.326 0.000
T67 Effects of heat and light
0.674 0.326 0.000
T71 Asphyxiation
0.674 0.326 0.000
T66 Unspecified effects of radiation
0.674 0.326 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.674 0.326 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.674 0.326 0.000
T83.2 Mechanical complication of graft of urinary organ
0.674 0.326 0.000
Q65 Congenital deformities of hip
0.674 0.326 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.674 0.326 0.000
E78.8 Other disorders of lipoprotein metabolism
0.672 0.328 0.000
Q64 Other congenital malformations of urinary system
0.671 0.329 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.671 0.329 0.000
M12 Other specific arthropathies
0.671 0.329 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.671 0.329 0.000
M08 Juvenile arthritis
0.671 0.329 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.669 0.331 0.000
O61 Failed induction of labour
0.669 0.331 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.668 0.332 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.667 0.333 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.667 0.333 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.667 0.333 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.667 0.333 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.667 0.333 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.667 0.333 0.000
M65 Synovitis and tenosynovitis
0.666 0.334 0.000
M60-M63 Disorders of muscles
0.666 0.334 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.666 0.334 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.666 0.334 0.000
G59.0 Diabetic mononeuropathy
0.665 0.335 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.664 0.335 0.000
E67 Other hyperalimentation
0.664 0.336 0.000
E68 Sequelae of hyperalimentation
0.664 0.336 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.664 0.336 0.000
O62 Abnormalities of forces of labour
0.664 0.336 0.000
M06.8 Other specified rheumatoid arthritis
0.664 0.336 0.000
M06.4 Inflammatory polyarthropathy
0.664 0.336 0.000
M06.2 Rheumatoid bursitis
0.664 0.336 0.000
M06.1 Adult-onset Still's disease
0.664 0.336 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.663 0.337 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.663 0.337 0.000
G46.4 Cerebellar stroke syndrome
0.663 0.337 0.000
F60-F69 Disorders of adult personality and behaviour
0.661 0.338 0.000
E73 Lactose intolerance
0.660 0.340 0.000
M54 Dorsalgia
0.660 0.340 0.000
I25.6 Silent myocardial ischaemia
0.660 0.340 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.658 0.342 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.658 0.342 0.000
O74 Complications of anaesthesia during labour and delivery
0.658 0.342 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.658 0.342 0.000
O60 Preterm delivery
0.658 0.342 0.000
O69.8 Labour and delivery complicated by other cord complications
0.658 0.342 0.000
S20-S29 Injuries to the thorax
0.658 0.342 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.656 0.344 0.000
L60-L75 Disorders of skin appendages
0.655 0.345 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.655 0.345 0.000
M53 Other dorsopathies, not elsewhere classified
0.655 0.345 0.000
O04 Medical abortion
0.654 0.345 0.000
M84 Disorders of continuity of bone
0.654 0.346 0.000
M07 Psoriatic and enteropathic arthropathies
0.654 0.346 0.000
H47.3 Other disorders of optic disk
0.654 0.346 0.000
M05 Seropositive rheumatoid arthritis
0.654 0.346 0.000
Q63.1 Lobulated, fused and horseshoe kidney
0.653 0.347 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.653 0.347 0.000
M06.3 Rheumatoid nodule
0.652 0.348 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.652 0.348 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.652 0.348 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.652 0.348 0.000
H15 Disorders of sclera
0.652 0.348 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.652 0.348 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.651 0.349 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.650 0.350 0.000
T59 Toxic effect of other gases, fumes and vapours
0.650 0.350 0.000
S63.1 Dislocation finger
0.649 0.350 0.000
S63.7 Sprain and strain of other and unspecified parts of hand
0.649 0.350 0.000
S63.3 Traumatic rupture of ligament of wrist and carpus
0.649 0.350 0.000
S63.2 Multiple dislocations of fingers
0.649 0.350 0.000
S63.0 Dislocation of wrist
0.649 0.350 0.000
E86 Volume depletion
0.648 0.352 0.000
M50.3 Other cervical disk degeneration
0.647 0.353 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.647 0.353 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.647 0.353 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.647 0.353 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.647 0.353 0.000
O69.3 Labour and delivery complicated by short cord
0.647 0.353 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.647 0.353 0.000
B95-B98 Bacterial, viral and other infectious agents
0.647 0.353 0.000
H54 Blindness and low vision
0.647 0.353 0.000
F99-F99 Unspecified mental disorder
0.644 0.356 0.000
G43.1 Migraine with aura [classical migraine]
0.644 0.356 0.000
G50 Disorders of trigeminal nerve
0.644 0.356 0.000
S72.4 Fracture of lower end of femur
0.642 0.357 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.642 0.358 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.640 0.360 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.639 0.361 0.000
M13 Other arthritis
0.638 0.362 0.000
G03 Meningitis due to other and unspecified causes
0.638 0.362 0.000
S78 Traumatic amputation of hip and thigh
0.637 0.363 0.000
S77 Crushing injury of hip and thigh
0.637 0.363 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.637 0.363 0.000
S75 Injury of blood vessels at hip and thigh level
0.637 0.363 0.000
S74 Injury of nerves at hip and thigh level
0.637 0.363 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.637 0.363 0.000
S71 Open wound of hip and thigh
0.637 0.363 0.000
M89 Other disorders of bone
0.637 0.363 0.000
G61 Inflammatory polyneuropathy
0.636 0.364 0.000
E13 Other specified diabetes mellitus
0.636 0.364 0.000
M86 Osteomyelitis
0.636 0.364 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.635 0.365 0.000
T78.9 Adverse effect, unspecified
0.634 0.365 0.000
T78.8 Other adverse effects, not elsewhere classified
0.634 0.365 0.000
Q89 Other congenital malformations, not elsewhere classified
0.634 0.366 0.000
E23.0 Hypopituitarism
0.633 0.367 0.000
H21.2 Degeneration of iris and ciliary body
0.632 0.368 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.632 0.368 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.632 0.368 0.000
O07 Failed attempted abortion
0.632 0.368 0.000
O06 Unspecified abortion
0.632 0.368 0.000
O05 Other abortion
0.632 0.368 0.000
O01 Hydatidiform mole
0.632 0.368 0.000
E65 Localised adiposity
0.632 0.368 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.631 0.369 0.000
E66.1 Drug-induced obesity
0.631 0.369 0.000
E66.0 Obesity due to excess calories
0.631 0.369 0.000
Q45 Other congenital malformations of digestive system
0.630 0.369 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.630 0.369 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.630 0.369 0.000
Q40 Other congenital malformations of upper alimentary tract
0.630 0.369 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.630 0.370 0.000
E00-E07 Disorders of thyroid gland
0.630 0.370 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.630 0.370 0.000
S64.8 Injury of other nerves at wrist and hand level
0.630 0.370 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.630 0.370 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.630 0.370 0.000
S64.1 Injury of median nerve at wrist and hand level
0.630 0.370 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.630 0.370 0.000
B37 Candidiasis
0.630 0.370 0.000
B25 Cytomegaloviral disease
0.629 0.371 0.000
L60 Nail disorders
0.628 0.372 0.000
G57 Mononeuropathies of lower limb
0.627 0.373 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.626 0.374 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.626 0.374 0.000
T20 Burn and corrosion of head and neck
0.625 0.374 0.000
S72.30 Fracture of shaft of femur (closed)
0.625 0.375 0.000
F23 Acute and transient psychotic disorders
0.624 0.376 0.000
S60.0 Contusion of finger(s) without damage to nail
0.624 0.376 0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection
0.624 0.376 0.000
T80.6 Other serum reactions
0.624 0.376 0.000
T80.5 Anaphylactic shock due to serum
0.624 0.376 0.000
T80.4 Rh incompatibility reaction
0.624 0.376 0.000
T80.3 ABO incompatibility reaction
0.624 0.376 0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection
0.624 0.376 0.000
T02 Fractures involving multiple body regions
0.624 0.376 0.000
O02.1 Missed abortion
0.623 0.377 0.000
S61.7 Multiple open wounds of wrist and hand
0.623 0.377 0.000
A07 Other protozoal intestinal diseases
0.622 0.378 0.000
A06 Amoebiasis
0.622 0.378 0.000
A05 Other bacterial foodborne intoxications
0.622 0.378 0.000
A03 Shigellosis
0.622 0.378 0.000
A01 Typhoid and paratyphoid fevers
0.622 0.378 0.000
A00 Cholera
0.622 0.378 0.000
A49 Bacterial infection of unspecified site
0.622 0.378 0.000
S79 Other and unspecified injuries of hip and thigh
0.620 0.380 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.620 0.380 0.000
H35.7 Separation of retinal layers
0.619 0.381 0.000
G58.9 Mononeuropathy, unspecified
0.619 0.381 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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