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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118118953
log Bayes Factor = 13.9369
Chromosome 22   position 34,002,123  (GRCh37) Explore rs118118953 on Ensembl!
Variant rs118118953 is part of Cluster X0142

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
I20-I25 Ischaemic heart diseases
0.991 0.009 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.989 0.011 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.988 0.012 0.000
Chapter I Certain infectious and parasitic diseases
0.986 0.014 0.000
Chapter X Diseases of the respiratory system
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.984 0.016 0.000
M20-M25 Other joint disorders
0.984 0.016 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.980 0.020 0.000
I25 Chronic ischaemic heart disease
0.976 0.024 0.000
B95-B98 Bacterial, viral and other infectious agents
0.974 0.026 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.970 0.030 0.000
Chapter VIII Diseases of the ear and mastoid process
0.970 0.030 0.000
O80-O84 Delivery
0.969 0.031 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.967 0.033 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.966 0.034 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.966 0.034 0.000
G40-G47 Episodic and paroxysmal disorders
0.964 0.036 0.000
S00-S09 Injuries to the head
0.964 0.036 0.000
I22 Subsequent myocardial infarction
0.961 0.039 0.000
I67 Other cerebrovascular diseases
0.958 0.042 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.958 0.042 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.955 0.045 0.000
O36 Maternal care for other known or suspected foetal problems
0.952 0.048 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.946 0.054 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.944 0.056 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.944 0.056 0.000
M25 Other joint disorders, not elsewhere classified
0.943 0.057 0.000
H65-H75 Diseases of middle ear and mastoid
0.939 0.061 0.000
I63 Cerebral infarction
0.938 0.062 0.000
O80 Single spontaneous delivery
0.938 0.062 0.000
M05-M14 Inflammatory polyarthropathies
0.937 0.063 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.935 0.065 0.000
O80.0 Spontaneous vertex delivery
0.924 0.076 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.922 0.078 0.000
E10-E14 Diabetes mellitus
0.922 0.078 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.920 0.080 0.000
S00 Superficial injury of head
0.919 0.081 0.000
O60-O75 Complications of labour and delivery
0.911 0.089 0.000
E10 Insulin-dependent diabetes mellitus
0.909 0.091 0.000
G40 Epilepsy
0.906 0.094 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.905 0.095 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.897 0.103 0.000
I63.9 Cerebral infarction, unspecified
0.896 0.104 0.000
O42 Premature rupture of membranes
0.893 0.107 0.000
I67.9 Cerebrovascular disease, unspecified
0.893 0.107 0.000
I67.8 Other specified cerebrovascular diseases
0.893 0.107 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.891 0.109 0.000
O48 Prolonged pregnancy
0.880 0.120 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.879 0.121 0.000
J09-J18 Influenza and pneumonia
0.879 0.121 0.000
J86 Pyothorax
0.877 0.123 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.873 0.127 0.000
G90-G99 Other disorders of the nervous system
0.872 0.128 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.866 0.134 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.865 0.135 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.865 0.135 0.000
J40-J47 Chronic lower respiratory diseases
0.863 0.137 0.000
M23 Internal derangement of knee
0.860 0.140 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.859 0.141 0.000
M31 Other necrotising vasculopathies
0.857 0.143 0.000
F30-F39 Mood [affective] disorders
0.851 0.149 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.850 0.150 0.000
J47 Bronchiectasis
0.850 0.150 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.846 0.154 0.000
M24 Other specific joint derangements
0.846 0.154 0.000
J86.9 Pyothorax without fistula
0.845 0.155 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.843 0.157 0.000
M06 Other rheumatoid arthritis
0.843 0.157 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.839 0.161 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.839 0.161 0.000
M25.7 Osteophyte
0.838 0.162 0.000
S60-S69 Injuries to the wrist and hand
0.838 0.162 0.000
M22 Disorders of patella
0.837 0.163 0.000
J95-J99 Other diseases of the respiratory system
0.834 0.166 0.000
Chapter XXII Codes for special purposes
0.834 0.166 0.000
B25-B34 Other viral diseases
0.833 0.167 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.828 0.172 0.000
I25.5 Ischaemic cardiomyopathy
0.828 0.172 0.000
E10.1 With ketoacidosis
0.827 0.173 0.000
H80-H83 Diseases of inner ear
0.827 0.173 0.000
Chapter XX External causes of morbidity and mortality
0.826 0.174 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.825 0.175 0.000
S02 Fracture of skull and facial bones
0.820 0.180 0.000
E70-E90 Metabolic disorders
0.817 0.183 0.000
M23.3 Other meniscus derangements
0.813 0.187 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.810 0.190 0.000
O36.8 Maternal care for other specified foetal problems
0.810 0.190 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.808 0.192 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.806 0.194 0.000
S00.8 Superficial injury of other parts of head
0.805 0.195 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.803 0.197 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.802 0.198 0.000
H65 Nonsuppurative otitis media
0.802 0.198 0.000
I25.2 Old myocardial infarction
0.799 0.201 0.000
O36.5 Maternal care for poor foetal growth
0.795 0.205 0.000
F10.0 Acute intoxication
0.795 0.205 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.793 0.207 0.000
G43 Migraine
0.793 0.207 0.000
O44 Placenta praevia
0.792 0.208 0.000
F60-F69 Disorders of adult personality and behaviour
0.792 0.208 0.000
M80-M85 Disorders of bone density and structure
0.789 0.211 0.000
H66 Suppurative and unspecified otitis media
0.786 0.214 0.000
F31 Bipolar affective disorder
0.785 0.215 0.000
I24 Other acute ischaemic heart diseases
0.783 0.217 0.000
O41 Other disorders of amniotic fluid and membranes
0.782 0.218 0.000
S70-S79 Injuries to the hip and thigh
0.782 0.218 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.782 0.218 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.781 0.219 0.000
F10.2 Dependence syndrome
0.778 0.222 0.000
I62 Other nontraumatic intracranial haemorrhage
0.777 0.223 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.777 0.223 0.000
S00.0 Superficial injury of scalp
0.775 0.225 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.775 0.225 0.000
M25.77 Osteophyte (Ankle and foot)
0.773 0.227 0.000
M10 Gout
0.772 0.228 0.000
O82 Single delivery by Caesarean section
0.772 0.228 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.771 0.229 0.000
M06.9 Rheumatoid arthritis, unspecified
0.769 0.231 0.000
I60 Subarachnoid haemorrhage
0.769 0.231 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.769 0.231 0.000
T86 Failure and rejection of transplanted organs and tissues
0.768 0.232 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.766 0.234 0.000
S06 Intracranial injury
0.763 0.237 0.000
E10.2 With renal complications
0.763 0.237 0.000
G45.4 Transient global amnesia
0.762 0.238 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.762 0.238 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.762 0.238 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.762 0.238 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.761 0.239 0.000
G20-G26 Extrapyramidal and movement disorders
0.761 0.239 0.000
T93 Sequelae of injuries of lower limb
0.760 0.240 0.000
H73 Other disorders of tympanic membrane
0.760 0.240 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.760 0.240 0.000
H70 Mastoiditis and related conditions
0.759 0.241 0.000
J90-J94 Other diseases of pleura
0.759 0.241 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.759 0.241 0.000
I69 Sequelae of cerebrovascular disease
0.758 0.242 0.000
I22.8 Subsequent myocardial infarction of other sites
0.758 0.242 0.000
M25.3 Other instability of joint
0.757 0.243 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.757 0.243 0.000
S00.1 Contusion of eyelid and periocular area
0.756 0.244 0.000
T87 Complications peculiar to reattachment and amputation
0.756 0.244 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.755 0.245 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.754 0.246 0.000
S90-S99 Injuries to the ankle and foot
0.753 0.247 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.753 0.247 0.000
J98 Other respiratory disorders
0.751 0.249 0.000
I30-I52 Other forms of heart disease
0.751 0.249 0.000
M05 Seropositive rheumatoid arthritis
0.750 0.249 0.000
E10.9 Without complications
0.750 0.250 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.749 0.251 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.748 0.252 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.748 0.252 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.747 0.253 0.000
M11 Other crystal arthropathies
0.746 0.254 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.744 0.256 0.000
G40.9 Epilepsy, unspecified
0.744 0.256 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.743 0.257 0.000
G62 Other polyneuropathies
0.742 0.258 0.000
H60-H62 Diseases of external ear
0.742 0.258 0.000
E10.5 With peripheral circulatory complications
0.742 0.258 0.000
F10.3 Withdrawal state
0.742 0.258 0.000
M22.4 Chondromalacia patellae
0.742 0.258 0.000
S10-S19 Injuries to the neck
0.741 0.259 0.000
G95 Other diseases of spinal cord
0.738 0.262 0.000
H72 Perforation of tympanic membrane
0.737 0.263 0.000
E14 Unspecified diabetes mellitus
0.737 0.263 0.000
I61 Intracerebral haemorrhage
0.737 0.263 0.000
M25.9 Joint disorder, unspecified
0.736 0.264 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.733 0.267 0.000
A80-A89 Viral infections of the central nervous system
0.732 0.268 0.000
J11 Influenza, virus not identified
0.732 0.268 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.731 0.269 0.000
O36.9 Maternal care for foetal problem, unspecified
0.730 0.270 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.729 0.271 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.729 0.271 0.000
I47 Paroxysmal tachycardia
0.729 0.271 0.000
E10.4 With neurological complications
0.728 0.272 0.000
M25.4 Effusion of joint
0.727 0.272 0.000
T39.1 4-Aminophenol derivatives
0.727 0.273 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.727 0.273 0.000
M35 Other systemic involvement of connective tissue
0.727 0.273 0.000
J60-J70 Lung diseases due to external agents
0.727 0.273 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.725 0.275 0.000
M91-M94 Chondropathies
0.725 0.275 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.723 0.277 0.000
H81 Disorders of vestibular function
0.723 0.277 0.000
B34 Viral infection of unspecified site
0.722 0.278 0.000
M00-M03 Infectious arthropathies
0.721 0.279 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.720 0.280 0.000
M23.5 Chronic instability of knee
0.720 0.280 0.000
E10.3 With ophthalmic complications
0.719 0.281 0.000
H71 Cholesteatoma of middle ear
0.719 0.281 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.718 0.282 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.715 0.285 0.000
O45 Premature separation of placenta [abruptio placentae]
0.714 0.285 0.000
O43 Placental disorders
0.714 0.285 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.714 0.285 0.000
O33 Maternal care for known or suspected disproportion
0.714 0.285 0.000
O31 Complications specific to multiple gestation
0.714 0.285 0.000
O40 Polyhydramnios
0.714 0.285 0.000
G70-G73 Diseases of myoneural junction and muscle
0.713 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.286 0.000
J42 Unspecified chronic bronchitis
0.713 0.287 0.000
B15-B19 Viral hepatitis
0.712 0.288 0.000
I23 Certain current complications following acute myocardial infarction
0.711 0.289 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.710 0.290 0.000
O71 Other obstetric trauma
0.710 0.290 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.710 0.290 0.000
I47.1 Supraventricular tachycardia
0.710 0.290 0.000
M24.1 Other articular cartilage disorders
0.709 0.291 0.000
O30 Multiple gestation
0.709 0.291 0.000
O66 Other obstructed labour
0.709 0.291 0.000
M31.6 Other giant cell arteritis
0.709 0.291 0.000
M60-M63 Disorders of muscles
0.709 0.291 0.000
O42.9 Premature rupture of membranes, unspecified
0.708 0.292 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.708 0.292 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.708 0.292 0.000
O72 Postpartum haemorrhage
0.708 0.292 0.000
B99-B99 Other infectious diseases
0.707 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.707 0.293 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.707 0.293 0.000
B65-B83 Helminthiases
0.707 0.293 0.000
B50-B64 Protozoal diseases
0.707 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.707 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.293 0.000
A75-A79 Rickettsioses
0.707 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.293 0.000
A65-A69 Other spirochaetal diseases
0.707 0.293 0.000
A20-A28 Certain zoonotic bacterial diseases
0.707 0.293 0.000
A15-A19 Tuberculosis
0.707 0.293 0.000
M31.3 Wegener's granulomatosis
0.707 0.293 0.000
G90 Disorders of autonomic nervous system
0.707 0.293 0.000
T66-T78 Other and unspecified effects of external causes
0.706 0.293 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.706 0.294 0.000
F80-F89 Disorders of psychological development
0.706 0.294 0.000
F70-F79 Mental retardation
0.706 0.294 0.000
I65.2 Occlusion and stenosis of carotid artery
0.706 0.294 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.705 0.294 0.000
M34 Systemic sclerosis
0.705 0.294 0.000
M33 Dermatopolymyositis
0.705 0.294 0.000
M32 Systemic lupus erythematosus
0.705 0.294 0.000
M30 Polyarteritis nodosa and related conditions
0.705 0.294 0.000
L90 Atrophic disorders of skin
0.703 0.297 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.703 0.297 0.000
O97 Death from sequelae of direct obstetric causes
0.703 0.297 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.703 0.297 0.000
O95 Obstetric death of unspecified cause
0.703 0.297 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.703 0.297 0.000
S09 Other and unspecified injuries of head
0.703 0.297 0.000
S00.3 Superficial injury of nose
0.703 0.297 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.702 0.298 0.000
G93 Other disorders of brain
0.702 0.298 0.000
T79-T79 Certain early complications of trauma
0.700 0.300 0.000
I25.6 Silent myocardial ischaemia
0.700 0.300 0.000
I25.4 Coronary artery aneurysm
0.700 0.300 0.000
I25.3 Aneurysm of heart
0.700 0.300 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.700 0.300 0.000
F99-F99 Unspecified mental disorder
0.699 0.301 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.699 0.301 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.699 0.301 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.699 0.301 0.000
M25.8 Other specified joint disorders
0.698 0.302 0.000
S64 Injury of nerves at wrist and hand level
0.697 0.303 0.000
E20-E35 Disorders of other endocrine glands
0.697 0.303 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.697 0.303 0.000
G51 Facial nerve disorders
0.696 0.304 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.696 0.304 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.696 0.304 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.696 0.304 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.695 0.304 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.695 0.305 0.000
O84 Multiple delivery
0.694 0.305 0.000
O83 Other assisted single delivery
0.694 0.305 0.000
O81 Single delivery by forceps and vacuum extractor
0.694 0.305 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.693 0.307 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.693 0.307 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.693 0.307 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.693 0.307 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.693 0.307 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.693 0.307 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.692 0.307 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.692 0.307 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.692 0.307 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.692 0.307 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.691 0.309 0.000
G41 Status epilepticus
0.691 0.309 0.000
S08 Traumatic amputation of part of head
0.691 0.309 0.000
S07 Crushing injury of head
0.691 0.309 0.000
S05 Injury of eye and orbit
0.691 0.309 0.000
S04 Injury of cranial nerves
0.691 0.309 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.691 0.309 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.691 0.309 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.689 0.311 0.000
G30-G32 Other degenerative diseases of the nervous system
0.689 0.311 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.688 0.312 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.688 0.312 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.687 0.313 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.687 0.313 0.000
I67.5 Moyamoya disease
0.687 0.313 0.000
I67.4 Hypertensive encephalopathy
0.687 0.313 0.000
I67.3 Progressive vascular leukoencephalopathy
0.687 0.313 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.687 0.313 0.000
M25.5 Pain in joint
0.687 0.313 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.685 0.315 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.685 0.315 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.684 0.316 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.683 0.316 0.000
M95.0 Acquired deformity of nose
0.683 0.317 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.682 0.317 0.000
O36.4 Maternal care for intra-uterine death
0.682 0.317 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.682 0.317 0.000
O36.2 Maternal care for hydrops foetalis
0.682 0.317 0.000
O36.1 Maternal care for other isoimmunisation
0.682 0.317 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.682 0.318 0.000
M86-M90 Other osteopathies
0.680 0.320 0.000
O00-O08 Pregnancy with abortive outcome
0.680 0.320 0.000
O61 Failed induction of labour
0.678 0.322 0.000
G60 Hereditary and idiopathic neuropathy
0.678 0.322 0.000
E40-E46 Malnutrition
0.677 0.323 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.677 0.323 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.677 0.323 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.677 0.323 0.000
T82.3 Mechanical complication of other vascular grafts
0.677 0.323 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.677 0.323 0.000
T82.1 Mechanical complication of cardiac electronic device
0.677 0.323 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.677 0.323 0.000
G43.9 Migraine, unspecified
0.677 0.323 0.000
M25.2 Flail joint
0.676 0.324 0.000
M25.1 Fistula of joint
0.676 0.324 0.000
M25.0 Haemarthrosis
0.676 0.324 0.000
W00-W19 Falls
0.675 0.325 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.675 0.325 0.000
H65.3 Chronic mucoid otitis media
0.675 0.325 0.000
S02.1 Fracture of base of skull
0.674 0.326 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.673 0.327 0.000
H74 Other disorders of middle ear and mastoid
0.673 0.327 0.000
H69 Other disorders of Eustachian tube
0.673 0.327 0.000
H68 Eustachian salpingitis and obstruction
0.673 0.327 0.000
H67 Otitis media in diseases classified elsewhere
0.673 0.327 0.000
M21 Other acquired deformities of limbs
0.673 0.327 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.673 0.327 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.673 0.327 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.673 0.327 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.673 0.327 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.673 0.327 0.000
O80.8 Other single spontaneous delivery
0.672 0.328 0.000
O80.1 Spontaneous breech delivery
0.672 0.328 0.000
M24.2 Disorder of ligament
0.672 0.328 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.672 0.328 0.000
M14 Arthropathies in other diseases classified elsewhere
0.672 0.328 0.000
M12 Other specific arthropathies
0.672 0.328 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.672 0.328 0.000
M08 Juvenile arthritis
0.672 0.328 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.671 0.329 0.000
I95 Hypotension
0.670 0.330 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.670 0.330 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.670 0.330 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.670 0.330 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.670 0.330 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.670 0.330 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.670 0.330 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
T36 Poisoning by systemic antibiotics
0.670 0.330 0.000
T39.0 Salicylates
0.670 0.330 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.669 0.331 0.000
F41 Other anxiety disorders
0.668 0.332 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.668 0.332 0.000
S02.2 Fracture of nasal bones
0.667 0.333 0.000
L57.0 Actinic keratosis
0.667 0.333 0.000
J98.1 Pulmonary collapse
0.666 0.334 0.000
S20-S29 Injuries to the thorax
0.666 0.334 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.665 0.334 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.665 0.335 0.000
S00.9 Superficial injury of head, part unspecified
0.664 0.336 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.664 0.336 0.000
M84 Disorders of continuity of bone
0.662 0.338 0.000
J20-J22 Other acute lower respiratory infections
0.661 0.339 0.000
J85 Abscess of lung and mediastinum
0.661 0.339 0.000
E13 Other specified diabetes mellitus
0.661 0.339 0.000
E12 Malnutrition-related diabetes mellitus
0.661 0.339 0.000
H66.9 Otitis media, unspecified
0.661 0.339 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.661 0.339 0.000
T51 Toxic effect of alcohol
0.660 0.340 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.660 0.340 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.660 0.340 0.000
S00.7 Multiple superficial injuries of head
0.659 0.341 0.000
S00.5 Superficial injury of lip and oral cavity
0.659 0.341 0.000
S00.4 Superficial injury of ear
0.659 0.341 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.659 0.341 0.000
S69 Other and unspecified injuries of wrist and hand
0.658 0.341 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.658 0.342 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.657 0.343 0.000
G62.8 Other specified polyneuropathies
0.657 0.343 0.000
T92 Sequelae of injuries of upper limb
0.656 0.344 0.000
M10.9 Gout, unspecified
0.654 0.346 0.000
F00 Dementia in Alzheimer's disease
0.654 0.346 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.654 0.346 0.000
F60 Specific personality disorders
0.654 0.346 0.000
L20-L30 Dermatitis and eczema
0.654 0.346 0.000
O74 Complications of anaesthesia during labour and delivery
0.653 0.347 0.000
O73 Retained placenta and membranes, without haemorrhage
0.653 0.347 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.653 0.347 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.653 0.347 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.653 0.347 0.000
O62 Abnormalities of forces of labour
0.653 0.347 0.000
O60 Preterm delivery
0.653 0.347 0.000
E10.8 With unspecified complications
0.652 0.348 0.000
E10.7 With multiple complications
0.652 0.348 0.000
E10.6 With other specified complications
0.652 0.348 0.000
E10.0 With coma
0.652 0.348 0.000
A00-A09 Intestinal infectious diseases
0.651 0.349 0.000
J30-J39 Other diseases of upper respiratory tract
0.651 0.349 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.651 0.349 0.000
F01 Vascular dementia
0.651 0.349 0.000
G40.8 Other epilepsy
0.650 0.350 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.650 0.350 0.000
G40.5 Special epileptic syndromes
0.650 0.350 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.650 0.350 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.650 0.350 0.000
O36.6 Maternal care for excessive foetal growth
0.649 0.350 0.000
F03 Unspecified dementia
0.649 0.351 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.649 0.351 0.000
G45.3 Amaurosis fugax
0.649 0.351 0.000
L90.0 Lichen sclerosus et atrophicus
0.649 0.351 0.000
V40-V49 Car occupant injured in transport accident
0.649 0.351 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.649 0.351 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.649 0.351 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.649 0.351 0.000
O34.6 Maternal care for abnormality of vagina
0.649 0.351 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.649 0.351 0.000
O34.4 Maternal care for other abnormalities of cervix
0.649 0.351 0.000
O34.3 Maternal care for cervical incompetence
0.649 0.351 0.000
O34.1 Maternal care for tumour of corpus uteri
0.649 0.351 0.000
O34.0 Maternal care for congenital malformation of uterus
0.649 0.351 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.648 0.352 0.000
A30-A49 Other bacterial diseases
0.648 0.352 0.000
H83 Other diseases of inner ear
0.647 0.353 0.000
S40-S49 Injuries to the shoulder and upper arm
0.647 0.353 0.000
O44.1 Placenta praevia with haemorrhage
0.646 0.354 0.000
G47 Sleep disorders
0.646 0.354 0.000
M13 Other arthritis
0.644 0.356 0.000
T90 Sequelae of injuries of head
0.644 0.356 0.000
G44 Other headache syndromes
0.643 0.356 0.000
B34.9 Viral infection, unspecified
0.643 0.357 0.000
T93.2 Sequelae of other fractures of lower limb
0.641 0.359 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.640 0.360 0.000
I63.8 Other cerebral infarction
0.640 0.360 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.640 0.360 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.640 0.360 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.639 0.361 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.639 0.361 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.639 0.361 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.639 0.361 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.639 0.361 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.639 0.361 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.639 0.361 0.000
F11 Mental and behavioural disorders due to use of opioids
0.639 0.361 0.000
I24.8 Other forms of acute ischaemic heart disease
0.639 0.361 0.000
G61 Inflammatory polyneuropathy
0.638 0.362 0.000
I51 Complications and ill-defined descriptions of heart disease
0.638 0.362 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.638 0.362 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.637 0.363 0.000
M07 Psoriatic and enteropathic arthropathies
0.636 0.364 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.635 0.365 0.000
G93.0 Cerebral cysts
0.635 0.365 0.000
O20 Haemorrhage in early pregnancy
0.635 0.365 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.635 0.365 0.000
F29 Unspecified nonorganic psychosis
0.635 0.365 0.000
L90.5 Scar conditions and fibrosis of skin
0.635 0.365 0.000
E87.6 Hypokalaemia
0.634 0.366 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.633 0.367 0.000
M25.74 Osteophyte (Hand)
0.633 0.367 0.000
H73.8 Other specified disorders of tympanic membrane
0.632 0.368 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.632 0.368 0.000
O63 Long labour
0.632 0.368 0.000
H70.9 Mastoiditis, unspecified
0.631 0.369 0.000
J17 Pneumonia in diseases classified elsewhere
0.630 0.370 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.630 0.370 0.000
J12 Viral pneumonia, not elsewhere classified
0.630 0.370 0.000
J10 Influenza due to identified influenza virus
0.630 0.370 0.000
J14 Pneumonia due to Haemophilus influenzae
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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