TreeWAS – Variant ID: rs118159639

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
M70-M79 Other soft tissue disorders	1.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001
M79 Other soft tissue disorders, not elsewhere classified	0.998	0.002
E10-E14 Diabetes mellitus	0.998	0.002
# Top node	0.997	0.003
M20-M25 Other joint disorders	0.995	0.005
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.994	0.006
E10 Insulin-dependent diabetes mellitus	0.992	0.008
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.980	0.020
Chapter IX Diseases of the circulatory system	0.977	0.023
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.973	0.027
E70-E90 Metabolic disorders	0.962	0.038
M21 Other acquired deformities of limbs	0.955	0.045
M79.8 Other specified soft tissue disorders	0.954	0.046
M25 Other joint disorders, not elsewhere classified	0.953	0.047
I70-I79 Diseases of arteries, arterioles and capillaries	0.952	0.048
T15-T19 Effects of foreign body entering through natural orifice	0.943	0.057
E11 Non-insulin-dependent diabetes mellitus	0.942	0.058
M45-M49 Spondylopathies	0.941	0.059
E10.1 With ketoacidosis	0.932	0.068
Chapter V Mental and behavioural disorders	0.932	0.068
M25.5 Pain in joint	0.928	0.072
M20 Acquired deformities of fingers and toes	0.927	0.073
I95-I99 Other and unspecified disorders of the circulatory system	0.927	0.073
M79.0 Rheumatism, unspecified	0.924	0.076
E86 Volume depletion	0.923	0.077
E10.9 Without complications	0.923	0.077
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.920	0.080
E50-E64 Other nutritional deficiencies	0.920	0.080
M77 Other enthesopathies	0.918	0.082
M72 Fibroblastic disorders	0.913	0.087
M25.4 Effusion of joint	0.898	0.102
M25.56 Pain in joint (Lower leg)	0.894	0.106
S10-S19 Injuries to the neck	0.892	0.108
E20-E35 Disorders of other endocrine glands	0.890	0.110
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.889	0.111
M20.2 Hallux rigidus	0.887	0.113
M25.57 Pain in joint (Ankle and foot)	0.885	0.115
I73 Other peripheral vascular diseases	0.881	0.119
T17 Foreign body in respiratory tract	0.880	0.120
M75 Shoulder lesions	0.880	0.120
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.877	0.123
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.877	0.123
E11.4 With neurological complications	0.875	0.125
M10 Gout	0.873	0.127
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.873	0.127
M79.89 Other specified soft tissue disorders (Site unspecified)	0.873	0.127
E10.3 With ophthalmic complications	0.869	0.131
M05 Seropositive rheumatoid arthritis	0.868	0.132
M47 Spondylosis	0.864	0.136
M21.0 Valgus deformity, not elsewhere classified	0.859	0.141
M79.09 Rheumatism, unspecified (Site unspecified)	0.859	0.141
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.855	0.145
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.854	0.146
T18 Foreign body in alimentary tract	0.853	0.147
T36-T50 Poisoning by drugs, medicaments and biological substances	0.853	0.147
M75.1 Rotator cuff syndrome	0.852	0.148
I30-I52 Other forms of heart disease	0.850	0.150
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.850	0.150
M79.6 Pain in limb	0.848	0.152
I99 Other and unspecified disorders of circulatory system	0.847	0.153
E53 Deficiency of other B group vitamins	0.840	0.160
I27 Other pulmonary heart diseases	0.839	0.161
M25.47 Effusion of joint (Ankle and foot)	0.835	0.165
E87 Other disorders of fluid, electrolyte and acid-base balance	0.835	0.165
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.833	0.167
I42 Cardiomyopathy	0.827	0.173
E10.5 With peripheral circulatory complications	0.825	0.175
M79.7 Fibromyalgia	0.822	0.178
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.820	0.180
M47.8 Other spondylosis	0.818	0.182
I73.0 Raynaud's syndrome	0.814	0.186
M79.1 Myalgia	0.813	0.187
F30-F39 Mood [affective] disorders	0.812	0.188
M21.3 Wrist or foot drop (acquired)	0.812	0.188
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.812	0.188
T17.2 Foreign body in pharynx	0.810	0.190
M79.82 Other specified soft tissue disorders (Upper arm)	0.807	0.193
Chapter XXII Codes for special purposes	0.805	0.195
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.804	0.196
M21.2 Flexion deformity	0.804	0.196
F20 Schizophrenia	0.804	0.196
E14 Unspecified diabetes mellitus	0.804	0.196
M65-M68 Disorders of synovium and tendon	0.801	0.199
M79.67 Pain in limb (Ankle and foot)	0.798	0.202
T20-T25 Burns and corrosions of external body surface, specified by site	0.798	0.202
M40-M43 Deforming dorsopathies	0.794	0.206
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.793	0.207
I72 Other aneurysm	0.793	0.207
M48 Other spondylopathies	0.793	0.207
E40-E46 Malnutrition	0.791	0.208
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.791	0.209
M07 Psoriatic and enteropathic arthropathies	0.790	0.210
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.788	0.212
E11.6 With other specified complications	0.786	0.214
M10.9 Gout, unspecified	0.783	0.217
M79.9 Soft tissue disorder, unspecified	0.781	0.219
I35 Nonrheumatic aortic valve disorders	0.780	0.220
S32 Fracture of lumbar spine and pelvis	0.778	0.222
I42.0 Dilated cardiomyopathy	0.778	0.222
E10.0 With coma	0.777	0.223
I47 Paroxysmal tachycardia	0.777	0.223
M70 Soft tissue disorders related to use, overuse and pressure	0.777	0.223
I74 Arterial embolism and thrombosis	0.777	0.223
M79.2 Neuralgia and neuritis, unspecified	0.776	0.224
M20.6 Acquired deformity of toe(s), unspecified	0.775	0.225
M05.9 Seropositive rheumatoid arthritis, unspecified	0.774	0.226
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.774	0.226
M77.1 Lateral epicondylitis	0.773	0.227
I27.2 Other secondary pulmonary hypertension	0.772	0.228
M86-M90 Other osteopathies	0.772	0.228
M79.80 Other specified soft tissue disorders (Multiple sites)	0.771	0.229
M76 Enthesopathies of lower limb, excluding foot	0.770	0.230
E27 Other disorders of adrenal gland	0.770	0.230
M20.4 Other hammer toe(s) (acquired)	0.769	0.231
M91-M94 Chondropathies	0.765	0.235
Q60-Q64 Congenital malformations of the urinary system	0.764	0.236
M46 Other inflammatory spondylopathies	0.764	0.236
E87.2 Acidosis	0.763	0.237
M77.0 Medial epicondylitis	0.763	0.237
E53.8 Deficiency of other specified B group vitamins	0.760	0.240
M32 Systemic lupus erythematosus	0.759	0.241
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.758	0.242
E11.0 With coma	0.757	0.243
Q38-Q45 Other congenital malformations of the digestive system	0.756	0.244
I27.8 Other specified pulmonary heart diseases	0.754	0.246
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.752	0.248
E80 Disorders of porphyrin and bilirubin metabolism	0.752	0.248
M79.83 Other specified soft tissue disorders (Forearm)	0.752	0.248
M24 Other specific joint derangements	0.750	0.249
M06.3 Rheumatoid nodule	0.749	0.251
E87.5 Hyperkalaemia	0.749	0.251
I77 Other disorders of arteries and arterioles	0.748	0.252
M79.84 Other specified soft tissue disorders (Hand)	0.747	0.252
T50.9 Other and unspecified drugs, medicaments and biological substances	0.747	0.253
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.745	0.255
I70 Atherosclerosis	0.744	0.256
E26 Hyperaldosteronism	0.744	0.256
D50-D53 Nutritional anaemias	0.744	0.256
M25.59 Pain in joint (Site unspecified)	0.741	0.259
M47.82 Other spondylosis (Cervical region)	0.741	0.259
M80-M85 Disorders of bone density and structure	0.740	0.260
M25.46 Effusion of joint (Lower leg)	0.740	0.260
I98 Other disorders of circulatory system in diseases classified elsewhere	0.737	0.263
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.737	0.263
I35.0 Aortic (valve) stenosis	0.736	0.264
S40-S49 Injuries to the shoulder and upper arm	0.736	0.264
F29 Unspecified nonorganic psychosis	0.735	0.265
M79.5 Residual foreign body in soft tissue	0.735	0.265
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.735	0.265
E85 Amyloidosis	0.734	0.265
S30 Superficial injury of abdomen, lower back and pelvis	0.734	0.266
E74 Other disorders of carbohydrate metabolism	0.734	0.266
S50-S59 Injuries to the elbow and forearm	0.734	0.266
M79.4 Hypertrophy of (infrapatellar) fat pad	0.733	0.267
I95 Hypotension	0.733	0.267
M47.89 Other spondylosis (Site unspecified)	0.733	0.267
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.731	0.269
E11.5 With peripheral circulatory complications	0.729	0.270
M60-M63 Disorders of muscles	0.729	0.271
M14 Arthropathies in other diseases classified elsewhere	0.729	0.271
E55 Vitamin D deficiency	0.728	0.271
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.726	0.274
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.724	0.276
E11.3 With ophthalmic complications	0.724	0.276
M77.9 Enthesopathy, unspecified	0.723	0.277
D80-D89 Certain disorders involving the immune mechanism	0.722	0.278
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.721	0.279
T17.9 Foreign body in respiratory tract, part unspecified	0.721	0.279
F31 Bipolar affective disorder	0.719	0.280
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.718	0.282
M73 Soft tissue disorders in diseases classified elsewhere	0.717	0.283
M12 Other specific arthropathies	0.717	0.283
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283
M08 Juvenile arthritis	0.717	0.283
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.717	0.283
M06.8 Other specified rheumatoid arthritis	0.717	0.283
M06.4 Inflammatory polyarthropathy	0.717	0.283
M06.2 Rheumatoid bursitis	0.717	0.283
M06.1 Adult-onset Still's disease	0.717	0.283
I47.2 Ventricular tachycardia	0.717	0.283
M79.3 Panniculitis, unspecified	0.716	0.284
E12 Malnutrition-related diabetes mellitus	0.715	0.285
Chapter XVI Certain conditions originating in the perinatal period	0.715	0.285
M20.5 Other deformities of toe(s) (acquired)	0.715	0.285
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.714	0.286
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.714	0.286
M33 Dermatopolymyositis	0.714	0.286
M30 Polyarteritis nodosa and related conditions	0.714	0.286
I42.9 Cardiomyopathy, unspecified	0.712	0.288
E10.8 With unspecified complications	0.711	0.288
E10.7 With multiple complications	0.711	0.288
E10.6 With other specified complications	0.711	0.288
T18.5 Foreign body in anus and rectum	0.711	0.289
M79.00 Rheumatism, unspecified (Multiple sites)	0.711	0.289
M31 Other necrotising vasculopathies	0.710	0.290
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.709	0.291
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.709	0.291
S10 Superficial injury of neck	0.708	0.292
I78 Diseases of capillaries	0.707	0.293
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.705	0.295
M22 Disorders of patella	0.704	0.296
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.703	0.297
S31 Open wound of abdomen, lower back and pelvis	0.702	0.297
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.702	0.298
F20.9 Schizophrenia, unspecified	0.702	0.298
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.701	0.299
M75.5 Bursitis of shoulder	0.701	0.299
I00-I02 Acute rheumatic fever	0.700	0.300
M06.0 Seronegative rheumatoid arthritis	0.700	0.300
S14 Injury of nerves and spinal cord at neck level	0.700	0.300
S19 Other and unspecified injuries of neck	0.699	0.301
T88 Other complications of surgical and medical care, not elsewhere classified	0.698	0.302
M79.63 Pain in limb (Forearm)	0.698	0.302
T33-T35 Frostbite	0.698	0.302
T26-T28 Burns and corrosions confined to eye and internal organs	0.698	0.302
T00-T07 Injuries involving multiple body regions	0.698	0.302
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.696	0.304
T18.9 Foreign body in alimentary tract, part unspecified	0.696	0.304
M35 Other systemic involvement of connective tissue	0.696	0.304
S90-S99 Injuries to the ankle and foot	0.694	0.306
I73.9 Peripheral vascular disease, unspecified	0.693	0.307
F60-F69 Disorders of adult personality and behaviour	0.692	0.308
M47.80 Other spondylosis (Multiple sites in spine)	0.692	0.308
E13 Other specified diabetes mellitus	0.691	0.309
Q20-Q28 Congenital malformations of the circulatory system	0.691	0.309
Q61 Cystic kidney disease	0.691	0.309
M47.2 Other spondylosis with radiculopathy	0.690	0.310
M00-M03 Infectious arthropathies	0.690	0.310
E84 Cystic fibrosis	0.690	0.310
E79 Disorders of purine and pyrimidine metabolism	0.690	0.310
E77 Disorders of glycoprotein metabolism	0.690	0.310
E76 Disorders of glycosaminoglycan metabolism	0.690	0.310
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.690	0.310
E73 Lactose intolerance	0.690	0.310
E72 Other disorders of amino-acid metabolism	0.690	0.310
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.690	0.310
E70 Disorders of aromatic amino-acid metabolism	0.690	0.310
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.690	0.310
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.689	0.311
M77.5 Other enthesopathy of foot	0.688	0.311
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.688	0.312
I30 Acute pericarditis	0.688	0.312
I72.4 Aneurysm of artery of lower extremity	0.688	0.312
I42.6 Alcoholic cardiomyopathy	0.688	0.312
S12 Fracture of neck	0.687	0.312
M34 Systemic sclerosis	0.687	0.313
F20.0 Paranoid schizophrenia	0.687	0.313
M25.0 Haemarthrosis	0.687	0.313
M79.79 Fibromyalgia (Site unspecified)	0.686	0.314
S32.5 Fracture of pubis	0.686	0.314
I37 Pulmonary valve disorders	0.685	0.314
T18.1 Foreign body in oesophagus	0.685	0.315
M21.9 Acquired deformity of limb, unspecified	0.685	0.315
M21.8 Other specified acquired deformities of limbs	0.685	0.315
M21.7 Unequal limb length (acquired)	0.685	0.315
M21.6 Other acquired deformities of ankle and foot	0.685	0.315
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.685	0.315
M21.4 Flat foot [pes planus] (acquired)	0.685	0.315
M25.50 Pain in joint (Multiple sites)	0.684	0.315
M79.88 Other specified soft tissue disorders (Other)	0.684	0.316
M79.81 Other specified soft tissue disorders (Shoulder region)	0.684	0.316
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.684	0.316
M48.0 Spinal stenosis	0.683	0.317
M25.2 Flail joint	0.683	0.317
M25.1 Fistula of joint	0.683	0.317
M79.69 Pain in limb (Site unspecified)	0.682	0.318
F80-F89 Disorders of psychological development	0.682	0.318
Q50-Q56 Congenital malformations of genital organs	0.681	0.319
I05-I09 Chronic rheumatic heart diseases	0.681	0.319
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.680	0.320
M71 Other bursopathies	0.680	0.320
M21.1 Varus deformity, not elsewhere classified	0.678	0.322
T19 Foreign body in genito-urinary tract	0.676	0.324
T15 Foreign body on external eye	0.676	0.324
T16 Foreign body in ear	0.676	0.324
E11.1 With ketoacidosis	0.676	0.324
E11.8 With unspecified complications	0.675	0.325
E11.7 With multiple complications	0.675	0.325
M49 Spondylopathies in diseases classified elsewhere	0.675	0.325
E10.2 With renal complications	0.674	0.326
M25.51 Pain in joint (Shoulder region)	0.674	0.326
E10.4 With neurological complications	0.673	0.327
D60-D64 Aplastic and other anaemias	0.673	0.327
E53.9 Vitamin B deficiency, unspecified	0.673	0.327
M41 Scoliosis	0.672	0.328
M25.3 Other instability of joint	0.671	0.329
E61 Deficiency of other nutrient elements	0.670	0.330
M11 Other crystal arthropathies	0.669	0.330
M77.12 Lateral epicondylitis (Upper arm)	0.669	0.331
I38 Endocarditis, valve unspecified	0.669	0.331
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.668	0.332
F70-F79 Mental retardation	0.668	0.332
F30 Manic episode	0.667	0.333
M25.9 Joint disorder, unspecified	0.666	0.334
M25.58 Pain in joint (Other)	0.666	0.334
E88 Other metabolic disorders	0.664	0.336
M79.08 Rheumatism, unspecified (Other)	0.662	0.337
M79.07 Rheumatism, unspecified (Ankle and foot)	0.662	0.337
M79.06 Rheumatism, unspecified (Lower leg)	0.662	0.337
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.662	0.337
M79.04 Rheumatism, unspecified (Hand)	0.662	0.337
M79.03 Rheumatism, unspecified (Forearm)	0.662	0.337
M79.02 Rheumatism, unspecified (Upper arm)	0.662	0.337
M79.01 Rheumatism, unspecified (Shoulder region)	0.662	0.337
Q80-Q89 Other congenital malformations	0.660	0.340
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.660	0.340
Q35-Q37 Cleft lip and cleft palate	0.660	0.340
Q30-Q34 Congenital malformations of the respiratory system	0.660	0.340
M21.24 Flexion deformity (Hand)	0.660	0.340
E64 Sequelae of malnutrition and other nutritional deficiencies	0.660	0.340
E63 Other nutritional deficiencies	0.660	0.340
E56 Other vitamin deficiencies	0.660	0.340
E51 Thiamine deficiency	0.660	0.340
E50 Vitamin A deficiency	0.660	0.340
E60 Dietary zinc deficiency	0.660	0.340
E59 Dietary selenium deficiency	0.660	0.340
E58 Dietary calcium deficiency	0.660	0.340
E54 Ascorbic acid deficiency	0.660	0.340
E52 Niacin deficiency [pellagra]	0.660	0.340
F00-F09 Organic, including symptomatic, mental disorders	0.659	0.341
F99-F99 Unspecified mental disorder	0.659	0.341
E14.8 With unspecified complications	0.659	0.341
M77.8 Other enthesopathies, not elsewhere classified	0.658	0.342
M77.3 Calcaneal spur	0.658	0.342
M77.2 Periarthritis of wrist	0.658	0.342
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.657	0.343
M72.9 Fibroblastic disorder, unspecified	0.654	0.346
M72.8 Other fibroblastic disorders	0.654	0.346
M72.6 Necrotizing fasciitis	0.654	0.346
M72.5 Fasciitis, not elsewhere classified	0.654	0.346
M72.4 Pseudosarcomatous fibromatosis	0.654	0.346
M72.3 Nodular fasciitis	0.654	0.346
M72.1 Knuckle pads	0.654	0.346
M79.10 Myalgia (Multiple sites)	0.654	0.346
M77.4 Metatarsalgia	0.653	0.346
M25.52 Pain in joint (Upper arm)	0.653	0.347
T79-T79 Certain early complications of trauma	0.652	0.348
D86 Sarcoidosis	0.652	0.348
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.651	0.349
M77.02 Medial epicondylitis (Upper arm)	0.651	0.349
E87.0 Hyperosmolality and hypernatraemia	0.650	0.350
I42.2 Other hypertrophic cardiomyopathy	0.649	0.351
D51 Vitamin B12 deficiency anaemia	0.648	0.352
M10.99 Gout, unspecified (Site unspecified)	0.648	0.352
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.646	0.353
I95.9 Hypotension, unspecified	0.646	0.354
E24 Cushing's syndrome	0.646	0.354
F25 Schizoaffective disorders	0.646	0.354
D68 Other coagulation defects	0.644	0.356
M25.49 Effusion of joint (Site unspecified)	0.644	0.356
M25.48 Effusion of joint (Other)	0.644	0.356
M25.45 Effusion of joint (Pelvic region and thigh)	0.644	0.356
M25.44 Effusion of joint (Hand)	0.644	0.356
M25.43 Effusion of joint (Forearm)	0.644	0.356
M25.42 Effusion of joint (Upper arm)	0.644	0.356
M25.41 Effusion of joint (Shoulder region)	0.644	0.356
M25.40 Effusion of joint (Multiple sites)	0.644	0.356
M48.06 Spinal stenosis (Lumbar region)	0.644	0.356
E46 Unspecified protein-energy malnutrition	0.643	0.357
T85 Complications of other internal prosthetic devices, implants and grafts	0.643	0.357
T21 Burn and corrosion of trunk	0.642	0.358
M65 Synovitis and tenosynovitis	0.641	0.359
M47.1 Other spondylosis with myelopathy	0.640	0.360
F39 Unspecified mood [affective] disorder	0.640	0.360
F22 Persistent delusional disorders	0.640	0.360
S17 Crushing injury of neck	0.640	0.360
S15 Injury of blood vessels at neck level	0.640	0.360
S11 Open wound of neck	0.640	0.360
S18 Traumatic amputation at neck level	0.640	0.360
S16 Injury of muscle and tendon at neck level	0.640	0.360
E26.0 Primary hyperaldosteronism	0.639	0.361
M07.3 Other psoriatic arthropathies	0.639	0.361
M72.2 Plantar fascial fibromatosis	0.638	0.362
E35 Disorders of endocrine glands in diseases classified elsewhere	0.638	0.362
E34 Other endocrine disorders	0.638	0.362
E32 Diseases of thymus	0.638	0.362
E31 Polyglandular dysfunction	0.638	0.362
E30 Disorders of puberty, not elsewhere classified	0.638	0.362
E25 Adrenogenital disorders	0.638	0.362
E20 Hypoparathyroidism	0.638	0.362
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.637	0.363
S37 Injury of urinary and pelvic organs	0.637	0.363
S36 Injury of intra-abdominal organs	0.637	0.363
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.637	0.363
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.637	0.363
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.637	0.363
E16 Other disorders of pancreatic internal secretion	0.637	0.363
M46.9 Inflammatory spondylopathy, unspecified	0.636	0.363
D55-D59 Haemolytic anaemias	0.634	0.366
M21.27 Flexion deformity (Ankle and foot)	0.633	0.367
E27.1 Primary adrenocortical insufficiency	0.633	0.367
I73.8 Other specified peripheral vascular diseases	0.632	0.368
I73.1 Thromboangiitis obliterans [Buerger]	0.632	0.368
E22 Hyperfunction of pituitary gland	0.632	0.368
T17.8 Foreign body in other and multiple parts of respiratory tract	0.631	0.369
T17.5 Foreign body in bronchus	0.631	0.369
T17.4 Foreign body in trachea	0.631	0.369
T17.3 Foreign body in larynx	0.631	0.369
T17.1 Foreign body in nostril	0.631	0.369
T17.0 Foreign body in nasal sinus	0.631	0.369
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.631	0.369
M75.8 Other shoulder lesions	0.631	0.369
M75.9 Shoulder lesion, unspecified	0.631	0.369
I74.0 Embolism and thrombosis of abdominal aorta	0.630	0.370
F28 Other nonorganic psychotic disorders	0.629	0.371
F24 Induced delusional disorder	0.629	0.371
F21 Schizotypal disorder	0.629	0.371
I28 Other diseases of pulmonary vessels	0.628	0.371
T87 Complications peculiar to reattachment and amputation	0.628	0.372
M10.94 Gout, unspecified (Hand)	0.627	0.373
M10.4 Other secondary gout	0.626	0.374
M10.3 Gout due to impairment of renal function	0.626	0.374
M10.2 Drug-induced gout	0.626	0.374
M10.1 Lead-induced gout	0.626	0.374
M10.0 Idiopathic gout	0.626	0.374
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.626	0.374
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.626	0.374
E27.2 Addisonian crisis	0.625	0.374
M05.8 Other seropositive rheumatoid arthritis	0.622	0.377
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.622	0.377
M05.2 Rheumatoid vasculitis	0.622	0.377
M05.1 Rheumatoid lung disease	0.622	0.377
M05.0 Felty's syndrome	0.622	0.377
E11.2 With renal complications	0.622	0.378
M20.3 Other deformity of hallux (acquired)	0.621	0.379
M79.18 Myalgia (Other)	0.621	0.379
D63 Anaemia in chronic diseases classified elsewhere	0.621	0.379
S32.50 Fracture of pubis (closed)	0.620	0.380
M47.0 Anterior spinal and vertebral artery compression syndromes	0.619	0.381
M70.4 Prepatellar bursitis	0.619	0.381
E78.0 Pure hypercholesterolaemia	0.619	0.381
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.618	0.382
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.618	0.382
I36 Nonrheumatic tricuspid valve disorders	0.617	0.383
M89 Other disorders of bone	0.617	0.383
Chapter XXI Factors influencing health status and contact with health services	0.617	0.383
T20 Burn and corrosion of head and neck	0.616	0.384
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.616	0.384
M21.08 Valgus deformity, not elsewhere classified (Other)	0.616	0.384
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.616	0.384
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.616	0.384
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.616	0.384
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.616	0.384
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.616	0.384
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.616	0.384
M92 Other juvenile osteochondrosis	0.616	0.384
E29 Testicular dysfunction	0.615	0.384
F23 Acute and transient psychotic disorders	0.615	0.385
I42.8 Other cardiomyopathies	0.614	0.386
M79.64 Pain in limb (Hand)	0.613	0.387
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.612	0.388
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.612	0.388
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.612	0.388
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.612	0.388
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.612	0.388
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.612	0.388
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.612	0.388
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.612	0.388
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.612	0.388
S46 Injury of muscle and tendon at shoulder and upper arm level	0.612	0.388
T18.8 Foreign body in other and multiple parts of alimentary tract	0.612	0.388
T18.4 Foreign body in colon	0.612	0.388
T18.3 Foreign body in small intestine	0.612	0.388
T18.2 Foreign body in stomach	0.612	0.388
T18.0 Foreign body in mouth	0.612	0.388
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.612	0.388
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.612	0.388
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.612	0.388
T41 Poisoning by anaesthetics and therapeutic gases	0.612	0.388
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.612	0.388
T36 Poisoning by systemic antibiotics	0.612	0.388
Q00-Q07 Congenital malformations of the nervous system	0.611	0.388
M10.96 Gout, unspecified (Lower leg)	0.611	0.389
I71 Aortic aneurysm and dissection	0.610	0.390
I52 Other heart disorders in diseases classified elsewhere	0.610	0.390
I48 Atrial fibrillation and flutter	0.610	0.390
I43 Cardiomyopathy in diseases classified elsewhere	0.610	0.390
I41 Myocarditis in diseases classified elsewhere	0.610	0.390
I40 Acute myocarditis	0.610	0.390
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.610	0.390
I32 Pericarditis in diseases classified elsewhere	0.610	0.390
I70.2 Atherosclerosis of arteries of the extremities	0.609	0.391
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.609	0.391
I77.9 Disorder of arteries and arterioles, unspecified	0.609	0.391
E89.2 Postprocedural hypoparathyroidism	0.609	0.391
I27.0 Primary pulmonary hypertension	0.609	0.391
M79.68 Pain in limb (Other)	0.608	0.392
M79.61 Pain in limb (Shoulder region)	0.608	0.392
F40-F48 Neurotic, stress-related and somatoform disorders	0.607	0.393
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.607	0.393
I44 Atrioventricular and left bundle-branch block	0.607	0.393
T86 Failure and rejection of transplanted organs and tissues	0.606	0.393
M79.70 Fibromyalgia (Multiple sites)	0.606	0.394
S32.0 Fracture of lumbar vertebra	0.606	0.394

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations