TreeWAS – Variant ID: rs11875185

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.132	0.868	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.132	0.868	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.128	0.872	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.126	0.874	0.000
O48 Prolonged pregnancy	0.126	0.874	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.122	0.878	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.122	0.878	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.119	0.881	0.000
O32.1 Maternal care for breech presentation	0.118	0.882	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.112	0.888	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.105	0.895	0.000
O32.8 Maternal care for other malpresentation of foetus	0.102	0.897	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.102	0.898	0.000
O85-O92 Complications predominantly related to the puerperium	0.102	0.898	0.000
O41 Other disorders of amniotic fluid and membranes	0.100	0.900	0.000
O42 Premature rupture of membranes	0.100	0.900	0.000
O44 Placenta praevia	0.099	0.901	0.000
O43 Placental disorders	0.097	0.903	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.096	0.904	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.095	0.905	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.095	0.905	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.095	0.905	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.095	0.905	0.000
O80-O84 Delivery	0.094	0.906	0.000
O36 Maternal care for other known or suspected foetal problems	0.094	0.906	0.000
O47 False labour	0.092	0.908	0.000
O45 Premature separation of placenta [abruptio placentae]	0.092	0.908	0.000
O33 Maternal care for known or suspected disproportion	0.092	0.908	0.000
O31 Complications specific to multiple gestation	0.092	0.908	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.090	0.910	0.000
O97 Death from sequelae of direct obstetric causes	0.090	0.910	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.090	0.910	0.000
O95 Obstetric death of unspecified cause	0.090	0.910	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.090	0.910	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.090	0.910	0.000
O40 Polyhydramnios	0.090	0.910	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.088	0.912	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.088	0.912	0.000
O32.6 Maternal care for compound presentation	0.088	0.912	0.000
O32.4 Maternal care for high head at term	0.088	0.912	0.000
O32.3 Maternal care for face, brow and chin presentation	0.088	0.912	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.087	0.913	0.000
O85 Puerperal sepsis	0.085	0.915	0.000
O46.9 Antepartum haemorrhage, unspecified	0.085	0.915	0.000
O26.2 Pregnancy care of habitual aborter	0.085	0.915	0.000
O26.9 Pregnancy-related condition, unspecified	0.084	0.916	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.083	0.917	0.000
O32.2 Maternal care for transverse and oblique lie	0.083	0.917	0.000
O82 Single delivery by Caesarean section	0.083	0.917	0.000
O36.8 Maternal care for other specified foetal problems	0.083	0.917	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.082	0.918	0.000
O42.9 Premature rupture of membranes, unspecified	0.082	0.918	0.000
O23 Infections of genito-urinary tract in pregnancy	0.082	0.918	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.082	0.918	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.082	0.918	0.000
O21 Excessive vomiting in pregnancy	0.081	0.919	0.000
O30 Multiple gestation	0.080	0.920	0.000
O82.0 Delivery by elective Caesarean section	0.077	0.923	0.000
O47.0 False labour before 37 completed weeks of gestation	0.077	0.923	0.000
O41.0 Oligohydramnios	0.077	0.923	0.000
O32.0 Maternal care for unstable lie	0.077	0.923	0.000
O87 Venous complications in the puerperium	0.077	0.923	0.000
O43.1 Malformation of placenta	0.076	0.924	0.000
O24 Diabetes mellitus in pregnancy	0.076	0.924	0.000
O29 Complications of anaesthesia during pregnancy	0.075	0.925	0.000
O22 Venous complications in pregnancy	0.075	0.925	0.000
O25 Malnutrition in pregnancy	0.075	0.925	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.075	0.925	0.000
O86 Other puerperal infections	0.074	0.926	0.000
O00-O08 Pregnancy with abortive outcome	0.074	0.926	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.073	0.926	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.073	0.927	0.000
O91 Infections of breast associated with childbirth	0.073	0.927	0.000
O89 Complications of anaesthesia during the puerperium	0.073	0.927	0.000
O88 Obstetric embolism	0.073	0.927	0.000
O46.8 Other antepartum haemorrhage	0.072	0.928	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.072	0.928	0.000
O41.1 Infection of amniotic sac and membranes	0.072	0.928	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.072	0.928	0.000
O90 Complications of the puerperium, not elsewhere classified	0.071	0.929	0.000
O36.6 Maternal care for excessive foetal growth	0.070	0.930	0.000
O43.9 Placental disorder, unspecified	0.070	0.930	0.000
O43.2 Morbidly adherent placenta	0.070	0.930	0.000
O43.0 Placental transfusion syndromes	0.070	0.930	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.069	0.931	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.069	0.931	0.000
O26.5 Maternal hypotension syndrome	0.069	0.931	0.000
O26.4 Herpes gestationis	0.069	0.931	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.069	0.931	0.000
O26.1 Low weight gain in pregnancy	0.069	0.931	0.000
O26.0 Excessive weight gain in pregnancy	0.069	0.931	0.000
O28 Abnormal findings on antenatal screening of mother	0.069	0.931	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.069	0.931	0.000
O81 Single delivery by forceps and vacuum extractor	0.068	0.931	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.068	0.932	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.068	0.932	0.000
O84 Multiple delivery	0.068	0.932	0.000
O83 Other assisted single delivery	0.068	0.932	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.067	0.932	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.067	0.932	0.000
O36.2 Maternal care for hydrops foetalis	0.067	0.932	0.000
O36.1 Maternal care for other isoimmunisation	0.067	0.932	0.000
O43.8 Other placental disorders	0.067	0.933	0.000
O31.8 Other complications specific to multiple gestation	0.066	0.934	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.066	0.934	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.066	0.934	0.000
O31.0 Papyraceous foetus	0.066	0.934	0.000
O33.9 Maternal care for disproportion, unspecified	0.066	0.934	0.000
O33.8 Maternal care for disproportion of other origin	0.066	0.934	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.066	0.934	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.066	0.934	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.066	0.934	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.066	0.934	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.066	0.934	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.066	0.934	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.066	0.934	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.066	0.934	0.000
O45.9 Premature separation of placenta, unspecified	0.066	0.934	0.000
O45.8 Other premature separation of placenta	0.066	0.934	0.000
O45.0 Premature separation of placenta with coagulation defect	0.066	0.934	0.000
O16 Unspecified maternal hypertension	0.066	0.934	0.000
O96.9 Death from unspecified obstetric cause	0.065	0.935	0.000
O96.1 Death from indirect obstetric cause	0.065	0.935	0.000
O96.0 Death from direct obstetric cause	0.065	0.935	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.065	0.935	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.065	0.935	0.000
O97.0 Death from sequelae of direct obstetric cause	0.065	0.935	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.065	0.935	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.065	0.935	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.065	0.935	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.065	0.935	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.065	0.935	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.065	0.935	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.065	0.935	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.065	0.935	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.065	0.935	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.065	0.935	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.065	0.935	0.000
O36.9 Maternal care for foetal problem, unspecified	0.064	0.936	0.000
O26.8 Other specified pregnancy-related conditions	0.064	0.936	0.000
O15 Eclampsia	0.063	0.936	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.063	0.936	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.063	0.937	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.062	0.937	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.062	0.937	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.062	0.937	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.062	0.937	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.062	0.937	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.062	0.937	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.062	0.937	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.062	0.937	0.000
O36.4 Maternal care for intra-uterine death	0.062	0.938	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.062	0.938	0.000
O44.1 Placenta praevia with haemorrhage	0.061	0.938	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.060	0.940	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.060	0.940	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.060	0.940	0.000
O47.9 False labour, unspecified	0.060	0.940	0.000
O82.8 Other single delivery by Caesarean section	0.060	0.940	0.000
O82.2 Delivery by Caesarean hysterectomy	0.060	0.940	0.000
O36.5 Maternal care for poor foetal growth	0.059	0.940	0.000
O04 Medical abortion	0.060	0.940	0.000
O86.2 Urinary tract infection following delivery	0.059	0.941	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.059	0.941	0.000
O23.5 Infections of the genital tract in pregnancy	0.059	0.941	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.059	0.941	0.000
O23.2 Infections of urethra in pregnancy	0.059	0.941	0.000
O23.1 Infections of bladder in pregnancy	0.059	0.941	0.000
O23.0 Infections of kidney in pregnancy	0.059	0.941	0.000
O21.0 Mild hyperemesis gravidarum	0.059	0.941	0.000
O87.2 Haemorrhoids in the puerperium	0.059	0.941	0.000
O21.8 Other vomiting complicating pregnancy	0.058	0.942	0.000
O21.2 Late vomiting of pregnancy	0.058	0.942	0.000
O30.9 Multiple gestation, unspecified	0.057	0.943	0.000
O30.8 Other multiple gestation	0.057	0.943	0.000
O30.2 Quadruplet pregnancy	0.057	0.943	0.000
O30.1 Triplet pregnancy	0.057	0.943	0.000
O21.9 Vomiting of pregnancy, unspecified	0.057	0.943	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.057	0.943	0.000
O82.1 Delivery by emergency Caesarean section	0.057	0.943	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.057	0.943	0.000
O00 Ectopic pregnancy	0.056	0.944	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.056	0.944	0.000
O87.9 Venous complication in the puerperium, unspecified	0.055	0.945	0.000
O87.8 Other venous complications in the puerperium	0.055	0.945	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.055	0.945	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.055	0.945	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.055	0.945	0.000
O82.9 Delivery by Caesarean section, unspecified	0.055	0.945	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.054	0.945	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.054	0.945	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.054	0.945	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.054	0.945	0.000
O22.9 Venous complication in pregnancy, unspecified	0.054	0.946	0.000
O22.8 Other venous complications in pregnancy	0.054	0.946	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.054	0.946	0.000
O22.4 Haemorrhoids in pregnancy	0.054	0.946	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.054	0.946	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.054	0.946	0.000
O22.1 Genital varices in pregnancy	0.054	0.946	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.054	0.946	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.054	0.946	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.054	0.946	0.000
O29.6 Failed or difficult intubation during pregnancy	0.054	0.946	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.054	0.946	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.054	0.946	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.054	0.946	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.054	0.946	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.054	0.946	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.054	0.946	0.000
O86.8 Other specified puerperal infections	0.053	0.947	0.000
O86.3 Other genito-urinary tract infections following delivery	0.053	0.947	0.000
O86.1 Other infection of genital tract following delivery	0.053	0.947	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.053	0.947	0.000
O07 Failed attempted abortion	0.053	0.947	0.000
O06 Unspecified abortion	0.053	0.947	0.000
O05 Other abortion	0.053	0.947	0.000
O01 Hydatidiform mole	0.053	0.947	0.000
O86.4 Pyrexia of unknown origin following delivery	0.053	0.947	0.000
O12.0 Gestational oedema	0.053	0.947	0.000
O88.8 Other obstetric embolism	0.052	0.947	0.000
O88.3 Obstetric pyaemic and septic embolism	0.052	0.947	0.000
O88.2 Obstetric blood-clot embolism	0.052	0.947	0.000
O88.1 Amniotic fluid embolism	0.052	0.947	0.000
O88.0 Obstetric air embolism	0.052	0.947	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.052	0.947	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.052	0.947	0.000
O89.6 Failed or difficult intubation during the puerperium	0.052	0.947	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.052	0.947	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.052	0.947	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.052	0.947	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.052	0.947	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.052	0.947	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.052	0.947	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.052	0.947	0.000
O91.1 Abscess of breast associated with childbirth	0.052	0.947	0.000
O91.0 Infection of nipple associated with childbirth	0.052	0.947	0.000
O92.7 Other and unspecified disorders of lactation	0.052	0.947	0.000
O92.6 Galactorrhoea	0.052	0.947	0.000
O92.5 Suppressed lactation	0.052	0.947	0.000
O92.4 Hypogalactia	0.052	0.947	0.000
O92.3 Agalactia	0.052	0.947	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.052	0.947	0.000
O92.1 Cracked nipple associated with childbirth	0.052	0.947	0.000
O92.0 Retracted nipple associated with childbirth	0.052	0.947	0.000
O12.1 Gestational proteinuria	0.051	0.948	0.000
O34.3 Maternal care for cervical incompetence	0.051	0.949	0.000
O90.9 Complication of the puerperium, unspecified	0.051	0.949	0.000
O90.5 Postpartum thyroiditis	0.051	0.949	0.000
O90.4 Postpartum acute renal failure	0.051	0.949	0.000
O90.3 Cardiomyopathy in the puerperium	0.051	0.949	0.000
O90.2 Haematoma of obstetric wound	0.051	0.949	0.000
O90.1 Disruption of perineal obstetric wound	0.051	0.949	0.000
O90.0 Disruption of Caesarean section wound	0.051	0.949	0.000
O20 Haemorrhage in early pregnancy	0.050	0.950	0.000
O81.4 Vacuum extractor delivery	0.050	0.950	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.049	0.950	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.049	0.950	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.049	0.950	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.049	0.950	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.049	0.950	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.049	0.950	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.049	0.950	0.000
O12.2 Gestational oedema with proteinuria	0.049	0.950	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.049	0.951	0.000
O81.3 Other and unspecified forceps delivery	0.049	0.951	0.000
O81.2 Mid-cavity forceps with rotation	0.049	0.951	0.000
O81.1 Mid-cavity forceps delivery	0.049	0.951	0.000
O81.0 Low forceps delivery	0.049	0.951	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.049	0.951	0.000
O34.6 Maternal care for abnormality of vagina	0.049	0.951	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.049	0.951	0.000
O34.4 Maternal care for other abnormalities of cervix	0.049	0.951	0.000
O34.0 Maternal care for congenital malformation of uterus	0.049	0.951	0.000
O83.9 Assisted single delivery, unspecified	0.049	0.951	0.000
O83.8 Other specified assisted single delivery	0.049	0.951	0.000
O83.4 Destructive operation for delivery	0.049	0.951	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.049	0.951	0.000
O83.2 Other manipulation-assisted delivery	0.049	0.951	0.000
O83.1 Other assisted breech delivery	0.049	0.951	0.000
O83.0 Breech extraction	0.049	0.951	0.000
O84.9 Multiple delivery, unspecified	0.049	0.951	0.000
O84.8 Other multiple delivery	0.049	0.951	0.000
O84.2 Multiple delivery, all by Caesarean section	0.049	0.951	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.049	0.951	0.000
O84.0 Multiple delivery, all spontaneous	0.049	0.951	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.049	0.951	0.000
O04.4 Incomplete, without complication	0.049	0.951	0.000
O14.1 Severe preeclampsia	0.049	0.951	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.048	0.951	0.000
O00.1 Tubal pregnancy	0.048	0.952	0.000
O80 Single spontaneous delivery	0.047	0.953	0.000
O86.0 Infection of obstetric surgical wound	0.047	0.953	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.047	0.953	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.047	0.953	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.047	0.953	0.000
O34.1 Maternal care for tumour of corpus uteri	0.046	0.954	0.000
O15.9 Eclampsia, unspecified as to time period	0.046	0.954	0.000
O15.2 Eclampsia in the puerperium	0.046	0.954	0.000
O15.1 Eclampsia in labour	0.046	0.954	0.000
O15.0 Eclampsia in pregnancy	0.046	0.954	0.000
O04.9 Complete or unspecified, without complication	0.046	0.954	0.000
O30.0 Twin pregnancy	0.045	0.955	0.000
O14.2 HELLP syndrome	0.044	0.956	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.043	0.956	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.043	0.956	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.043	0.956	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.043	0.956	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.043	0.956	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.043	0.957	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.043	0.957	0.000
O04.7 Complete or unspecified, complicated by embolism	0.043	0.957	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.043	0.957	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.043	0.957	0.000
O04.3 Incomplete, with other and unspecified complications	0.043	0.957	0.000
O04.2 Incomplete, complicated by embolism	0.043	0.957	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.043	0.957	0.000
O14.0 Moderate preeclampsia	0.041	0.959	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.041	0.959	0.000
O00.8 Other ectopic pregnancy	0.040	0.959	0.000
O00.2 Ovarian pregnancy	0.040	0.959	0.000
O00.0 Abdominal pregnancy	0.040	0.959	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.040	0.960	0.000
O03 Spontaneous abortion	0.040	0.960	0.000
O14.9 Preeclampsia, unspecified	0.040	0.960	0.000
O80.9 Single spontaneous delivery, unspecified	0.039	0.961	0.000
O01.9 Hydatidiform mole, unspecified	0.038	0.961	0.000
O01.1 Incomplete and partial hydatidiform mole	0.038	0.961	0.000
O01.0 Classical hydatidiform mole	0.038	0.961	0.000
O05.9 Complete or unspecified, without complication	0.038	0.961	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.038	0.961	0.000
O05.7 Complete or unspecified, complicated by embolism	0.038	0.961	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.038	0.961	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.038	0.961	0.000
O05.4 Incomplete, without complication	0.038	0.961	0.000
O05.3 Incomplete, with other and unspecified complications	0.038	0.961	0.000
O05.2 Incomplete, complicated by embolism	0.038	0.961	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.038	0.961	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.038	0.961	0.000
O06.9 Complete or unspecified, without complication	0.038	0.961	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.038	0.961	0.000
O06.7 Complete or unspecified, complicated by embolism	0.038	0.961	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.038	0.961	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.038	0.961	0.000
O06.4 Incomplete, without complication	0.038	0.961	0.000
O06.3 Incomplete, with other and unspecified complications	0.038	0.961	0.000
O06.2 Incomplete, complicated by embolism	0.038	0.961	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.038	0.961	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.038	0.961	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.038	0.961	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.038	0.961	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.038	0.961	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.038	0.961	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.038	0.961	0.000
O07.4 Failed medical abortion, without complication	0.038	0.961	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.038	0.961	0.000
O07.2 Failed medical abortion, complicated by embolism	0.038	0.961	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.038	0.961	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.038	0.961	0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.038	0.961	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.038	0.961	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.038	0.961	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.038	0.961	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.038	0.961	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.038	0.961	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.038	0.961	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.038	0.961	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.038	0.961	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.038	0.961	0.000
O02 Other abnormal products of conception	0.038	0.962	0.000
O20.8 Other haemorrhage in early pregnancy	0.035	0.964	0.000
O80.1 Spontaneous breech delivery	0.034	0.966	0.000
O00.9 Ectopic pregnancy, unspecified	0.033	0.966	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.031	0.969	0.000
O80.8 Other single spontaneous delivery	0.031	0.969	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.030	0.970	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.030	0.970	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.029	0.971	0.000
O03.7 Complete or unspecified, complicated by embolism	0.029	0.971	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.029	0.971	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.029	0.971	0.000
O03.3 Incomplete, with other and unspecified complications	0.029	0.971	0.000
O03.2 Incomplete, complicated by embolism	0.029	0.971	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.029	0.971	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.029	0.971	0.000
O02.9 Abnormal product of conception, unspecified	0.027	0.972	0.000
O02.8 Other specified abnormal products of conception	0.027	0.972	0.000
O03.4 Incomplete, without complication	0.026	0.974	0.000
O20.0 Threatened abortion	0.025	0.975	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.976	0.024
O03.9 Complete or unspecified, without complication	0.022	0.978	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.986	0.014
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.988	0.012
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.988	0.011
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.989	0.011
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.989	0.011
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.990	0.010
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.990	0.010
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.991	0.009
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.992	0.008
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.992	0.008
O80.0 Spontaneous vertex delivery	0.008	0.992	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.993	0.007
C71.9 Brain, unspecified	0.007	0.993	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.994	0.006
O02.1 Missed abortion	0.005	0.994	0.001
C71 Malignant neoplasm of brain	0.006	0.994	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.995	0.005
F31.9 Bipolar affective disorder, unspecified	0.000	0.995	0.005
F31 Bipolar affective disorder	0.000	0.995	0.005
D32.0 Cerebral meninges	0.005	0.995	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.995	0.005
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.995	0.005
C71.2 Temporal lobe	0.005	0.995	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.995	0.005
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.995	0.005
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.995	0.005
C71.3 Parietal lobe	0.005	0.995	0.000
C71.0 Cerebrum, except lobes and ventricles	0.004	0.995	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.995	0.004
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.996	0.004
C71.1 Frontal lobe	0.004	0.996	0.000
N63 Unspecified lump in breast	0.000	0.996	0.004
C71.8 Overlapping lesion of brain	0.004	0.996	0.000
C71.7 Brain stem	0.004	0.996	0.000
C71.6 Cerebellum	0.004	0.996	0.000
C71.5 Cerebral ventricle	0.004	0.996	0.000
C71.4 Occipital lobe	0.004	0.996	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.996	0.004
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.996	0.004
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.996	0.004
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.996	0.004
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.996	0.004
F31.8 Other bipolar affective disorders	0.000	0.996	0.004
F31.7 Bipolar affective disorder, currently in remission	0.000	0.996	0.004
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.996	0.004
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.996	0.004
B37.8 Candidiasis of other sites	0.000	0.996	0.004
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.996	0.004
F32 Depressive episode	0.000	0.996	0.004
F32.1 Moderate depressive episode	0.000	0.996	0.004
F30-F39 Mood [affective] disorders	0.000	0.996	0.004
F32.9 Depressive episode, unspecified	0.000	0.997	0.003
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.997	0.003
F33 Recurrent depressive disorder	0.000	0.997	0.003
F32.8 Other depressive episodes	0.000	0.997	0.003
R87.6 Abnormal cytological findings	0.000	0.997	0.003
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.997	0.003
F38 Other mood [affective] disorders	0.000	0.997	0.003
F34 Persistent mood [affective] disorders	0.000	0.997	0.003
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.997	0.003
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.003	0.997	0.000
F32.0 Mild depressive episode	0.000	0.997	0.003
F39 Unspecified mood [affective] disorder	0.000	0.997	0.003
Z93.6 Other artificial openings of urinary tract status	0.000	0.997	0.003
D32 Benign neoplasm of meninges	0.003	0.997	0.000
F30 Manic episode	0.000	0.997	0.003
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.997	0.003
Q76.0 Spina bifida occulta	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
O60-O75 Complications of labour and delivery	0.003	0.997	0.000
N95.2 Postmenopausal atrophic vaginitis	0.000	0.997	0.003
Q05.9 Spina bifida, unspecified	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
D32.9 Meninges, unspecified	0.003	0.997	0.000
F33.8 Other recurrent depressive disorders	0.000	0.997	0.002
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.997	0.002
F33.9 Recurrent depressive disorder, unspecified	0.000	0.997	0.002
B37 Candidiasis	0.000	0.997	0.003
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.998	0.002
F34.8 Other persistent mood [affective] disorders	0.000	0.998	0.002
F34.1 Dysthymia	0.000	0.998	0.002
F34.0 Cyclothymia	0.000	0.998	0.002
F38.8 Other specified mood [affective] disorders	0.000	0.998	0.002
F38.1 Other recurrent mood [affective] disorders	0.000	0.998	0.002
F38.0 Other single mood [affective] disorders	0.000	0.998	0.002
Q05 Spina bifida	0.002	0.998	0.000
N94.6 Dysmenorrhoea, unspecified	0.002	0.998	0.000
D32.1 Spinal meninges	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.002
Q65 Congenital deformities of hip	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
F30.8 Other manic episodes	0.000	0.998	0.002
F30.2 Mania with psychotic symptoms	0.000	0.998	0.002
F30.1 Mania without psychotic symptoms	0.000	0.998	0.002
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
B37.3 Candidiasis of vulva and vagina	0.000	0.998	0.002
F30.9 Manic episode, unspecified	0.000	0.998	0.002
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
T88.4 Failed or difficult intubation	0.000	0.998	0.002
Q78 Other osteochondrodysplasias	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations