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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11947645
log Bayes Factor = 1.43698
Chromosome 4   position 151,101,672  (GRCh37) Explore rs11947645 on Ensembl!
Variant rs11947645 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
0.959 0.041 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.958 0.042 0.000
C60-C63 Malignant neoplasms of male genital organs
0.958 0.042 0.000
C61 Malignant neoplasm of prostate
0.956 0.044 0.000
# Top node
0.956 0.044 0.000
Chapter VII Diseases of the eye and adnexa
0.949 0.051 0.000
D10-D36 Benign neoplasms
0.924 0.076 0.000
H30-H36 Disorders of choroid and retina
0.918 0.082 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.912 0.088 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.912 0.088 0.000
O60-O75 Complications of labour and delivery
0.911 0.089 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.896 0.104 0.000
Chapter V Mental and behavioural disorders
0.881 0.119 0.000
H35 Other retinal disorders
0.880 0.120 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.879 0.121 0.000
D12.0 Caecum
0.878 0.122 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.865 0.135 0.000
H43-H45 Disorders of vitreous body and globe
0.859 0.141 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.855 0.145 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.852 0.148 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.848 0.152 0.000
D12.8 Rectum
0.847 0.153 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.847 0.153 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.845 0.155 0.000
C15-C26 Malignant neoplasms of digestive organs
0.843 0.157 0.000
D10 Benign neoplasm of mouth and pharynx
0.828 0.171 0.000
D27 Benign neoplasm of ovary
0.824 0.176 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.822 0.178 0.000
H35.3 Degeneration of macula and posterior pole
0.815 0.185 0.000
D12.5 Sigmoid colon
0.810 0.190 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.808 0.192 0.000
F41 Other anxiety disorders
0.808 0.192 0.000
E70-E90 Metabolic disorders
0.794 0.206 0.000
F41.9 Anxiety disorder, unspecified
0.792 0.208 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.791 0.209 0.000
D12.7 Rectosigmoid junction
0.788 0.212 0.000
Chapter I Certain infectious and parasitic diseases
0.787 0.213 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.785 0.215 0.000
O26.8 Other specified pregnancy-related conditions
0.783 0.217 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.783 0.217 0.000
H55-H59 Other disorders of eye and adnexa
0.782 0.218 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.780 0.220 0.000
O72 Postpartum haemorrhage
0.778 0.222 0.000
H00 Hordeolum and chalazion
0.778 0.222 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.777 0.223 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.774 0.226 0.000
H33 Retinal detachments and breaks
0.774 0.226 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.772 0.228 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.765 0.234 0.000
H43 Disorders of vitreous body
0.764 0.236 0.000
F43 Reaction to severe stress, and adjustment disorders
0.763 0.237 0.000
O16 Unspecified maternal hypertension
0.761 0.239 0.000
L60-L75 Disorders of skin appendages
0.759 0.241 0.000
Chapter VI Diseases of the nervous system
0.759 0.241 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.758 0.242 0.000
C62 Malignant neoplasm of testis
0.757 0.243 0.000
Chapter XXI Factors influencing health status and contact with health services
0.757 0.243 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.751 0.249 0.000
D10.3 Other and unspecified parts of mouth
0.750 0.250 0.000
H35.4 Peripheral retinal degeneration
0.746 0.253 0.000
O26.9 Pregnancy-related condition, unspecified
0.742 0.258 0.000
O63 Long labour
0.740 0.260 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.738 0.262 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.737 0.263 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.732 0.268 0.000
D12.9 Anus and anal canal
0.728 0.272 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.727 0.273 0.000
Chapter XXII Codes for special purposes
0.726 0.274 0.000
H00.1 Chalazion
0.720 0.280 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.718 0.282 0.000
G90-G99 Other disorders of the nervous system
0.716 0.284 0.000
E86 Volume depletion
0.714 0.286 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.714 0.286 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.712 0.288 0.000
O80-O84 Delivery
0.711 0.289 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.710 0.290 0.000
B95-B98 Bacterial, viral and other infectious agents
0.703 0.297 0.000
H36 Retinal disorders in diseases classified elsewhere
0.702 0.298 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.701 0.299 0.000
Z36 Antenatal screening
0.698 0.302 0.000
C18 Malignant neoplasm of colon
0.698 0.302 0.000
L60 Nail disorders
0.695 0.305 0.000
E88 Other metabolic disorders
0.695 0.305 0.000
E87.6 Hypokalaemia
0.694 0.306 0.000
H44 Disorders of globe
0.693 0.307 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.692 0.307 0.000
D36 Benign neoplasm of other and unspecified sites
0.692 0.308 0.000
H53-H54 Visual disturbances and blindness
0.692 0.308 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.687 0.312 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.687 0.312 0.000
O85-O92 Complications predominantly related to the puerperium
0.687 0.313 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.686 0.313 0.000
C60 Malignant neoplasm of penis
0.686 0.313 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.686 0.314 0.000
H02 Other disorders of eyelid
0.686 0.314 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.685 0.314 0.000
H35.7 Separation of retinal layers
0.684 0.316 0.000
O72.1 Other immediate postpartum haemorrhage
0.683 0.317 0.000
C16 Malignant neoplasm of stomach
0.682 0.318 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.681 0.319 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.680 0.320 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.677 0.323 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.676 0.324 0.000
E10-E14 Diabetes mellitus
0.675 0.325 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.675 0.325 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.674 0.326 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.670 0.330 0.000
A30-A49 Other bacterial diseases
0.669 0.331 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.667 0.332 0.000
F30-F39 Mood [affective] disorders
0.666 0.334 0.000
O73 Retained placenta and membranes, without haemorrhage
0.665 0.335 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.663 0.337 0.000
D31 Benign neoplasm of eye and adnexa
0.662 0.337 0.000
D30 Benign neoplasm of urinary organs
0.662 0.337 0.000
D29 Benign neoplasm of male genital organs
0.662 0.337 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.662 0.337 0.000
D26 Other benign neoplasms of uterus
0.662 0.337 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.662 0.337 0.000
D19 Benign neoplasm of mesothelial tissue
0.662 0.337 0.000
D16 Benign neoplasm of bone and articular cartilage
0.662 0.337 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.662 0.337 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.662 0.337 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.662 0.338 0.000
H57 Other disorders of eye and adnexa
0.662 0.338 0.000
H10-H13 Disorders of conjunctiva
0.662 0.338 0.000
Z35 Supervision of high-risk pregnancy
0.661 0.339 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.660 0.339 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.660 0.340 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.659 0.341 0.000
L40-L45 Papulosquamous disorders
0.659 0.341 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.658 0.342 0.000
H31 Other disorders of choroid
0.658 0.342 0.000
H30 Chorioretinal inflammation
0.658 0.342 0.000
H05 Disorders of orbit
0.657 0.343 0.000
D12.2 Ascending colon
0.656 0.344 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.654 0.346 0.000
O97 Death from sequelae of direct obstetric causes
0.654 0.346 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.654 0.346 0.000
O95 Obstetric death of unspecified cause
0.654 0.346 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.654 0.346 0.000
D12.1 Appendix
0.654 0.346 0.000
O74 Complications of anaesthesia during labour and delivery
0.653 0.347 0.000
O71 Other obstetric trauma
0.653 0.347 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.653 0.347 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.653 0.347 0.000
O62 Abnormalities of forces of labour
0.653 0.347 0.000
O61 Failed induction of labour
0.653 0.347 0.000
O60 Preterm delivery
0.653 0.347 0.000
L60.0 Ingrowing nail
0.653 0.347 0.000
O66 Other obstructed labour
0.652 0.348 0.000
F60-F69 Disorders of adult personality and behaviour
0.649 0.351 0.000
Q60-Q64 Congenital malformations of the urinary system
0.647 0.353 0.000
H43.8 Other disorders of vitreous body
0.646 0.354 0.000
C25 Malignant neoplasm of pancreas
0.645 0.355 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.644 0.356 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.644 0.356 0.000
O29 Complications of anaesthesia during pregnancy
0.642 0.358 0.000
O28 Abnormal findings on antenatal screening of mother
0.642 0.358 0.000
O24 Diabetes mellitus in pregnancy
0.642 0.358 0.000
O23 Infections of genito-urinary tract in pregnancy
0.642 0.358 0.000
O22 Venous complications in pregnancy
0.642 0.358 0.000
O21 Excessive vomiting in pregnancy
0.642 0.358 0.000
O25 Malnutrition in pregnancy
0.642 0.358 0.000
F40 Phobic anxiety disorders
0.641 0.359 0.000
H43.1 Vitreous haemorrhage
0.640 0.360 0.000
F43.2 Adjustment disorders
0.639 0.361 0.000
O20 Haemorrhage in early pregnancy
0.638 0.362 0.000
E50-E64 Other nutritional deficiencies
0.637 0.363 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.636 0.364 0.000
H01 Other inflammation of eyelid
0.635 0.365 0.000
E10 Insulin-dependent diabetes mellitus
0.635 0.365 0.000
H35.8 Other specified retinal disorders
0.633 0.367 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.632 0.368 0.000
F70-F79 Mental retardation
0.632 0.368 0.000
F80-F89 Disorders of psychological development
0.632 0.368 0.000
H35.9 Retinal disorder, unspecified
0.631 0.369 0.000
H35.6 Retinal haemorrhage
0.631 0.369 0.000
H35.5 Hereditary retinal dystrophy
0.631 0.369 0.000
H35.2 Other proliferative retinopathy
0.631 0.369 0.000
H35.1 Retinopathy of prematurity
0.631 0.369 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.631 0.369 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.631 0.369 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.631 0.369 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.631 0.369 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.631 0.369 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.631 0.369 0.000
O36 Maternal care for other known or suspected foetal problems
0.630 0.370 0.000
H35.0 Background retinopathy and retinal vascular changes
0.630 0.370 0.000
O63.1 Prolonged second stage (of labour)
0.628 0.372 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.628 0.372 0.000
D13.2 Duodenum
0.627 0.372 0.000
D33.3 Cranial nerves
0.627 0.373 0.000
D22 Melanocytic naevi
0.625 0.375 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.625 0.375 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.624 0.376 0.000
D10.1 Tongue
0.624 0.376 0.000
D46 Myelodysplastic syndromes
0.623 0.377 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.623 0.377 0.000
G95 Other diseases of spinal cord
0.623 0.377 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.622 0.378 0.000
F43.1 Posttraumatic stress disorder
0.622 0.378 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.620 0.379 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.620 0.379 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.620 0.380 0.000
O47 False labour
0.620 0.380 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.620 0.380 0.000
O44 Placenta praevia
0.620 0.380 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.619 0.380 0.000
Z33 Pregnant state, incidental
0.619 0.381 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.618 0.381 0.000
D18 Haemangioma and lymphangioma, any site
0.618 0.382 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.616 0.384 0.000
C73 Malignant neoplasm of thyroid gland
0.615 0.385 0.000
H02.9 Disorder of eyelid, unspecified
0.614 0.386 0.000
D25 Leiomyoma of uterus
0.614 0.386 0.000
C62.9 Testis, unspecified
0.614 0.386 0.000
D13.1 Stomach
0.614 0.386 0.000
F48 Other neurotic disorders
0.613 0.387 0.000
F44 Dissociative [conversion] disorders
0.613 0.387 0.000
F42 Obsessive-compulsive disorder
0.613 0.387 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.611 0.389 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.611 0.389 0.000
O26.5 Maternal hypotension syndrome
0.611 0.389 0.000
O26.4 Herpes gestationis
0.611 0.389 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.611 0.389 0.000
O26.2 Pregnancy care of habitual aborter
0.611 0.389 0.000
O26.1 Low weight gain in pregnancy
0.611 0.389 0.000
O26.0 Excessive weight gain in pregnancy
0.611 0.389 0.000
H33.2 Serous retinal detachment
0.611 0.389 0.000
H02.3 Blepharochalasis
0.610 0.390 0.000
L10-L14 Bullous disorders
0.608 0.392 0.000
O15 Eclampsia
0.607 0.392 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.607 0.392 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.607 0.392 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.607 0.392 0.000
F99-F99 Unspecified mental disorder
0.607 0.393 0.000
H33.0 Retinal detachment with retinal break
0.607 0.393 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.606 0.394 0.000
E40-E46 Malnutrition
0.606 0.394 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.606 0.394 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.605 0.394 0.000
C45 Mesothelioma
0.605 0.394 0.000
D11 Benign neoplasm of major salivary glands
0.605 0.395 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.605 0.395 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.605 0.395 0.000
C21 Malignant neoplasm of anus and anal canal
0.605 0.395 0.000
C17 Malignant neoplasm of small intestine
0.605 0.395 0.000
C23 Malignant neoplasm of gallbladder
0.605 0.395 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.603 0.397 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.602 0.397 0.000
A49 Bacterial infection of unspecified site
0.602 0.398 0.000
O75.8 Other specified complications of labour and delivery
0.601 0.399 0.000
L50-L54 Urticaria and erythema
0.601 0.399 0.000
G30-G32 Other degenerative diseases of the nervous system
0.599 0.400 0.000
L20-L30 Dermatitis and eczema
0.599 0.401 0.000
Z02 Examination and encounter for administrative purposes
0.599 0.401 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.596 0.404 0.000
L73 Other follicular disorders
0.595 0.405 0.000
G93 Other disorders of brain
0.595 0.405 0.000
D10.9 Pharynx, unspecified
0.594 0.406 0.000
D10.7 Hypopharynx
0.594 0.406 0.000
D10.6 Nasopharynx
0.594 0.406 0.000
D10.5 Other parts of oropharynx
0.594 0.406 0.000
D10.4 Tonsil
0.594 0.406 0.000
D10.2 Floor of mouth
0.594 0.406 0.000
D10.0 Lip
0.594 0.406 0.000
E00-E07 Disorders of thyroid gland
0.594 0.406 0.000
O00-O08 Pregnancy with abortive outcome
0.593 0.407 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.592 0.408 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.592 0.408 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.592 0.408 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.591 0.409 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.591 0.409 0.000
H34 Retinal vascular occlusions
0.590 0.410 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.589 0.411 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.588 0.412 0.000
F43.0 Acute stress reaction
0.587 0.413 0.000
O32.1 Maternal care for breech presentation
0.585 0.415 0.000
F41.1 Generalised anxiety disorder
0.584 0.415 0.000
H21 Other disorders of iris and ciliary body
0.584 0.416 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.584 0.416 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.580 0.420 0.000
O45 Premature separation of placenta [abruptio placentae]
0.580 0.420 0.000
O43 Placental disorders
0.580 0.420 0.000
O41 Other disorders of amniotic fluid and membranes
0.580 0.420 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.580 0.420 0.000
O33 Maternal care for known or suspected disproportion
0.580 0.420 0.000
O31 Complications specific to multiple gestation
0.580 0.420 0.000
O30 Multiple gestation
0.580 0.420 0.000
O40 Polyhydramnios
0.580 0.420 0.000
F41.8 Other specified anxiety disorders
0.579 0.420 0.000
F41.3 Other mixed anxiety disorders
0.579 0.420 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.579 0.421 0.000
H33.5 Other retinal detachments
0.579 0.421 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.578 0.422 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.577 0.422 0.000
H04 Disorders of lachrymal system
0.577 0.423 0.000
Z04 Examination and observation for other reasons
0.575 0.425 0.000
H44.2 Degenerative myopia
0.575 0.425 0.000
B35-B49 Mycoses
0.574 0.426 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.574 0.426 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.573 0.427 0.000
L71 Rosacea
0.572 0.427 0.000
C18.9 Colon, unspecified
0.572 0.428 0.000
L83 Acanthosis nigricans
0.571 0.429 0.000
E85 Amyloidosis
0.569 0.431 0.000
E84 Cystic fibrosis
0.569 0.431 0.000
E79 Disorders of purine and pyrimidine metabolism
0.569 0.431 0.000
E77 Disorders of glycoprotein metabolism
0.569 0.431 0.000
E76 Disorders of glycosaminoglycan metabolism
0.569 0.431 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.569 0.431 0.000
E74 Other disorders of carbohydrate metabolism
0.569 0.431 0.000
E73 Lactose intolerance
0.569 0.431 0.000
E72 Other disorders of amino-acid metabolism
0.569 0.431 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.569 0.431 0.000
E70 Disorders of aromatic amino-acid metabolism
0.569 0.431 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.569 0.431 0.000
O32.0 Maternal care for unstable lie
0.569 0.431 0.000
D34 Benign neoplasm of thyroid gland
0.569 0.431 0.000
E10.3 With ophthalmic complications
0.568 0.432 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.567 0.433 0.000
Z31 Procreative management
0.567 0.433 0.000
H33.3 Retinal breaks without detachment
0.567 0.433 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.567 0.433 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.564 0.436 0.000
B99-B99 Other infectious diseases
0.564 0.436 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.564 0.436 0.000
B65-B83 Helminthiases
0.564 0.436 0.000
B50-B64 Protozoal diseases
0.564 0.436 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.564 0.436 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.564 0.436 0.000
A80-A89 Viral infections of the central nervous system
0.564 0.436 0.000
A75-A79 Rickettsioses
0.564 0.436 0.000
A70-A74 Other diseases caused by chlamydiae
0.564 0.436 0.000
A65-A69 Other spirochaetal diseases
0.564 0.436 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.564 0.436 0.000
A20-A28 Certain zoonotic bacterial diseases
0.564 0.436 0.000
A15-A19 Tuberculosis
0.564 0.436 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.564 0.436 0.000
C44 Other malignant neoplasms of skin
0.564 0.436 0.000
O75.9 Complication of labour and delivery, unspecified
0.563 0.437 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.563 0.437 0.000
O75.4 Other complications of obstetric surgery and procedures
0.563 0.437 0.000
O75.3 Other infection during labour
0.563 0.437 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.563 0.437 0.000
O75.1 Shock during or following labour and delivery
0.563 0.437 0.000
O75.0 Maternal distress during labour and delivery
0.563 0.437 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.561 0.438 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.561 0.438 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.561 0.438 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.561 0.438 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.561 0.438 0.000
F31 Bipolar affective disorder
0.561 0.439 0.000
C18.0 Caecum
0.561 0.439 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.561 0.439 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.561 0.439 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.561 0.439 0.000
H55 Nystagmus and other irregular eye movements
0.561 0.439 0.000
B15-B19 Viral hepatitis
0.560 0.440 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.559 0.441 0.000
C95 Leukaemia of unspecified cell type
0.559 0.441 0.000
C94 Other leukaemias of specified cell type
0.559 0.441 0.000
C93 Monocytic leukaemia
0.559 0.441 0.000
C92 Myeloid leukaemia
0.559 0.441 0.000
C88 Malignant immunoproliferative diseases
0.559 0.441 0.000
C86 Other specified types of T/NK-cell lymphoma
0.559 0.441 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.559 0.441 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.559 0.441 0.000
O72.3 Postpartum coagulation defects
0.558 0.442 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.558 0.442 0.000
O72.0 Third-stage haemorrhage
0.558 0.442 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.557 0.443 0.000
Q80-Q89 Other congenital malformations
0.557 0.443 0.000
Q50-Q56 Congenital malformations of genital organs
0.557 0.443 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.557 0.443 0.000
Q35-Q37 Cleft lip and cleft palate
0.557 0.443 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.557 0.443 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.557 0.443 0.000
Q00-Q07 Congenital malformations of the nervous system
0.557 0.443 0.000
O82 Single delivery by Caesarean section
0.557 0.443 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.556 0.444 0.000
D13.9 Ill-defined sites within the digestive system
0.555 0.445 0.000
D13.7 Endocrine pancreas
0.555 0.445 0.000
D13.6 Pancreas
0.555 0.445 0.000
D13.5 Extrahepatic bile ducts
0.555 0.445 0.000
D13.4 Liver
0.555 0.445 0.000
D13.3 Other and unspecified parts of small intestine
0.555 0.445 0.000
D13.0 Oesophagus
0.555 0.445 0.000
H33.4 Traction detachment of retina
0.555 0.445 0.000
H33.1 Retinoschisis and retinal cysts
0.555 0.445 0.000
C91 Lymphoid leukaemia
0.555 0.445 0.000
F45 Somatoform disorders
0.554 0.446 0.000
Q61 Cystic kidney disease
0.554 0.446 0.000
F30 Manic episode
0.554 0.446 0.000
Z34 Supervision of normal pregnancy
0.552 0.448 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.549 0.451 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.549 0.451 0.000
C46 Kaposi's sarcoma
0.549 0.451 0.000
C64-C68 Malignant neoplasms of urinary tract
0.549 0.451 0.000
H43.9 Disorder of vitreous body, unspecified
0.548 0.452 0.000
H43.3 Other vitreous opacities
0.548 0.452 0.000
H43.2 Crystalline deposits in vitreous body
0.548 0.452 0.000
H43.0 Vitreous prolapse
0.548 0.452 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.547 0.453 0.000
F43.9 Reaction to severe stress, unspecified
0.547 0.453 0.000
F43.8 Other reactions to severe stress
0.547 0.453 0.000
H36.0 Diabetic retinopathy
0.546 0.453 0.000
C81 Hodgkin's disease
0.546 0.454 0.000
E87.7 Fluid overload
0.546 0.454 0.000
C16.0 Cardia
0.546 0.454 0.000
D45 Polycythaemia vera
0.544 0.455 0.000
H40-H42 Glaucoma
0.544 0.455 0.000
L75 Apocrine sweat disorders
0.544 0.456 0.000
L74 Eccrine sweat disorders
0.544 0.456 0.000
L70 Acne
0.544 0.456 0.000
L68 Hypertrichosis
0.544 0.456 0.000
L67 Hair colour and hair shaft abnormalities
0.544 0.456 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.544 0.456 0.000
L65 Other nonscarring hair loss
0.544 0.456 0.000
L64 Androgenic alopecia
0.544 0.456 0.000
L63 Alopecia areata
0.544 0.456 0.000
L62 Nail disorders in diseases classified elsewhere
0.544 0.456 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.544 0.456 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.544 0.456 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.544 0.456 0.000
C74 Malignant neoplasm of adrenal gland
0.544 0.456 0.000
C62.1 Descended testis
0.543 0.457 0.000
C62.0 Undescended testis
0.543 0.457 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.542 0.458 0.000
D00-D09 In situ neoplasms
0.542 0.458 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.541 0.459 0.000
Z02.8 Other examinations for administrative purposes
0.540 0.460 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.540 0.460 0.000
L93 Lupus erythematosus
0.539 0.461 0.000
D32 Benign neoplasm of meninges
0.538 0.461 0.000
D33.9 Central nervous system, unspecified
0.538 0.461 0.000
D33.7 Other specified parts of central nervous system
0.538 0.461 0.000
D33.4 Spinal cord
0.538 0.461 0.000
D33.2 Brain, unspecified
0.538 0.461 0.000
D33.1 Brain, infratentorial
0.538 0.461 0.000
D33.0 Brain, supratentorial
0.538 0.461 0.000
Z39 Postpartum care and examination
0.538 0.462 0.000
O63.9 Long labour, unspecified
0.537 0.463 0.000
G91 Hydrocephalus
0.537 0.463 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.537 0.463 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.535 0.464 0.000
C18.4 Transverse colon
0.535 0.465 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.534 0.466 0.000
H16 Keratitis
0.533 0.467 0.000
O36.8 Maternal care for other specified foetal problems
0.532 0.468 0.000
C20 Malignant neoplasm of rectum
0.532 0.468 0.000
C09 Malignant neoplasm of tonsil
0.531 0.469 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.531 0.469 0.000
E13 Other specified diabetes mellitus
0.530 0.470 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.530 0.470 0.000
G70-G73 Diseases of myoneural junction and muscle
0.530 0.470 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.529 0.471 0.000
E87.4 Mixed disorder of acid-base balance
0.529 0.471 0.000
E87.3 Alkalosis
0.529 0.471 0.000
E87.0 Hyperosmolality and hypernatraemia
0.529 0.471 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.526 0.473 0.000
G35 Multiple sclerosis
0.526 0.474 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.525 0.474 0.000
G95.2 Cord compression, unspecified
0.525 0.475 0.000
Z38 Liveborn infants according to place of birth
0.524 0.475 0.000
Z32 Pregnancy examination and test
0.524 0.475 0.000
O14.9 Preeclampsia, unspecified
0.524 0.475 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.524 0.476 0.000
A46 Erysipelas
0.524 0.476 0.000
C18.2 Ascending colon
0.524 0.476 0.000
C25.0 Head of pancreas
0.522 0.478 0.000
E10.1 With ketoacidosis
0.521 0.479 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.521 0.479 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.521 0.479 0.000
H17 Corneal scars and opacities
0.521 0.479 0.000
H15 Disorders of sclera
0.521 0.479 0.000
L43 Lichen planus
0.521 0.479 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.520 0.479 0.000
E10.4 With neurological complications
0.520 0.480 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.520 0.480 0.000
D22.5 Melanocytic naevi of trunk
0.519 0.481 0.000
H57.1 Ocular pain
0.519 0.481 0.000
Z36.8 Other antenatal screening
0.519 0.481 0.000
E20-E35 Disorders of other endocrine glands
0.519 0.481 0.000
C85.1 B-cell lymphoma, unspecified
0.518 0.482 0.000
H18 Other disorders of cornea
0.518 0.482 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.518 0.482 0.000
C16.9 Stomach, unspecified
0.518 0.482 0.000
E55 Vitamin D deficiency
0.517 0.483 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.516 0.484 0.000
H52 Disorders of refraction and accommodation
0.516 0.484 0.000
D25.1 Intramural leiomyoma of uterus
0.515 0.485 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.514 0.485 0.000
O69.8 Labour and delivery complicated by other cord complications
0.514 0.485 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.514 0.485 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.514 0.485 0.000
O69.3 Labour and delivery complicated by short cord
0.514 0.485 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.514 0.485 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.513 0.486 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.513 0.486 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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