TreeWAS – Variant ID: rs11969073

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
I21 Acute myocardial infarction	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004
S00-S09 Injuries to the head	0.989	0.011
I21.9 Acute myocardial infarction, unspecified	0.986	0.014
I46 Cardiac arrest	0.985	0.015
I25.1 Atherosclerotic heart disease	0.984	0.016
I25.2 Old myocardial infarction	0.984	0.016
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.983	0.017
I42 Cardiomyopathy	0.981	0.019
I25.8 Other forms of chronic ischaemic heart disease	0.977	0.023
# Top node	0.974	0.026
I60-I69 Cerebrovascular diseases	0.969	0.031
Chapter V Mental and behavioural disorders	0.966	0.034
I46.9 Cardiac arrest, unspecified	0.966	0.034
I21.1 Acute transmural myocardial infarction of inferior wall	0.958	0.042
I61 Intracerebral haemorrhage	0.953	0.047
S50-S59 Injuries to the elbow and forearm	0.950	0.050
S06 Intracranial injury	0.945	0.055
S32 Fracture of lumbar spine and pelvis	0.944	0.056
Chapter XII Diseases of the skin and subcutaneous tissue	0.944	0.056
S02 Fracture of skull and facial bones	0.943	0.057
F00-F09 Organic, including symptomatic, mental disorders	0.942	0.058
I22 Subsequent myocardial infarction	0.937	0.063
L40-L45 Papulosquamous disorders	0.914	0.086
I42.9 Cardiomyopathy, unspecified	0.912	0.088
I61.9 Intracerebral haemorrhage, unspecified	0.909	0.091
I05-I09 Chronic rheumatic heart diseases	0.904	0.096
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.903	0.097
I33 Acute and subacute endocarditis	0.899	0.101
S51 Open wound of forearm	0.890	0.110
L40 Psoriasis	0.890	0.110
I95-I99 Other and unspecified disorders of the circulatory system	0.890	0.110
T36-T50 Poisoning by drugs, medicaments and biological substances	0.883	0.117
I21.0 Acute transmural myocardial infarction of anterior wall	0.879	0.121
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.878	0.122
S06.6 Traumatic subarachnoid haemorrhage	0.873	0.127
L40.9 Psoriasis, unspecified	0.871	0.129
S32.5 Fracture of pubis	0.870	0.130
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.867	0.133
I45 Other conduction disorders	0.866	0.134
I38 Endocarditis, valve unspecified	0.866	0.134
F01 Vascular dementia	0.864	0.136
S31 Open wound of abdomen, lower back and pelvis	0.864	0.136
S02.1 Fracture of base of skull	0.862	0.138
I25.9 Chronic ischaemic heart disease, unspecified	0.860	0.140
S10-S19 Injuries to the neck	0.859	0.141
L00-L08 Infections of the skin and subcutaneous tissue	0.857	0.143
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.850	0.150
S90-S99 Injuries to the ankle and foot	0.849	0.151
S40-S49 Injuries to the shoulder and upper arm	0.847	0.153
I36 Nonrheumatic tricuspid valve disorders	0.838	0.162
I60 Subarachnoid haemorrhage	0.838	0.162
I22.9 Subsequent myocardial infarction of unspecified site	0.838	0.162
I30 Acute pericarditis	0.829	0.171
I46.0 Cardiac arrest with successful resuscitation	0.828	0.172
I42.0 Dilated cardiomyopathy	0.828	0.172
I33.0 Acute and subacute infective endocarditis	0.827	0.173
S51.0 Open wound of elbow	0.823	0.177
S06.5 Traumatic subdural haemorrhage	0.822	0.178
L50-L54 Urticaria and erythema	0.822	0.178
S60-S69 Injuries to the wrist and hand	0.822	0.178
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.821	0.179
I95 Hypotension	0.819	0.181
L03 Cellulitis	0.819	0.181
I62 Other nontraumatic intracranial haemorrhage	0.819	0.181
S09 Other and unspecified injuries of head	0.818	0.182
S32.50 Fracture of pubis (closed)	0.817	0.183
I42.2 Other hypertrophic cardiomyopathy	0.817	0.183
I61.8 Other intracerebral haemorrhage	0.812	0.188
F01.9 Vascular dementia, unspecified	0.809	0.191
Chapter I Certain infectious and parasitic diseases	0.809	0.191
I37 Pulmonary valve disorders	0.805	0.194
S02.10 Fracture of base of skull (closed)	0.805	0.195
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.801	0.199
F25 Schizoaffective disorders	0.797	0.203
S30 Superficial injury of abdomen, lower back and pelvis	0.797	0.203
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.796	0.204
S02.4 Fracture of malar and maxillary bones	0.785	0.215
T90 Sequelae of injuries of head	0.785	0.215
F06.7 Mild cognitive disorder	0.784	0.216
I22.8 Subsequent myocardial infarction of other sites	0.782	0.218
I42.1 Obstructive hypertrophic cardiomyopathy	0.781	0.219
I23 Certain current complications following acute myocardial infarction	0.780	0.220
S56 Injury of muscle and tendon at forearm level	0.775	0.225
S32.1 Fracture of sacrum	0.769	0.230
Chapter XX External causes of morbidity and mortality	0.769	0.231
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.769	0.231
S50 Superficial injury of forearm	0.769	0.231
I47 Paroxysmal tachycardia	0.767	0.233
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.760	0.240
F20 Schizophrenia	0.760	0.240
S02.3 Fracture of orbital floor	0.759	0.241
I08 Multiple valve diseases	0.758	0.242
I61.3 Intracerebral haemorrhage in brain stem	0.757	0.242
T20-T25 Burns and corrosions of external body surface, specified by site	0.757	0.243
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.757	0.243
I50 Heart failure	0.757	0.243
I25.5 Ischaemic cardiomyopathy	0.756	0.244
I42.8 Other cardiomyopathies	0.755	0.245
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.753	0.247
L03.2 Cellulitis of face	0.753	0.247
I05 Rheumatic mitral valve diseases	0.752	0.247
S32.4 Fracture of acetabulum	0.752	0.248
S06.3 Focal brain injury	0.751	0.249
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.750	0.250
F30-F39 Mood [affective] disorders	0.747	0.253
I95.1 Orthostatic hypotension	0.745	0.255
S05 Injury of eye and orbit	0.743	0.257
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.735	0.265
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.734	0.266
L03.9 Cellulitis, unspecified	0.734	0.266
I69 Sequelae of cerebrovascular disease	0.733	0.267
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.733	0.267
I45.1 Other and unspecified right bundle-branch block	0.732	0.268
F22 Persistent delusional disorders	0.732	0.268
I50.0 Congestive heart failure	0.731	0.269
F02 Dementia in other diseases classified elsewhere	0.731	0.269
S02.0 Fracture of vault of skull	0.730	0.269
S06.8 Other intracranial injuries	0.729	0.270
F03 Unspecified dementia	0.728	0.272
B15-B19 Viral hepatitis	0.726	0.274
Q38-Q45 Other congenital malformations of the digestive system	0.725	0.275
S54 Injury of nerves at forearm level	0.725	0.275
I22.1 Subsequent myocardial infarction of inferior wall	0.725	0.275
S66 Injury of muscle and tendon at wrist and hand level	0.724	0.276
S42 Fracture of shoulder and upper arm	0.723	0.277
T00-T07 Injuries involving multiple body regions	0.722	0.277
S00 Superficial injury of head	0.722	0.278
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.722	0.278
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.722	0.278
T15-T19 Effects of foreign body entering through natural orifice	0.719	0.281
I27 Other pulmonary heart diseases	0.719	0.281
I00-I02 Acute rheumatic fever	0.717	0.283
T79-T79 Certain early complications of trauma	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
I47.2 Ventricular tachycardia	0.716	0.284
F00 Dementia in Alzheimer's disease	0.716	0.284
I21.X Presumed acute myicardial infaction (unconfirmed)	0.716	0.284
T33-T35 Frostbite	0.714	0.286
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286
S40 Superficial injury of shoulder and upper arm	0.713	0.287
I21.3 Acute transmural myocardial infarction of unspecified site	0.711	0.288
S31.8 Open wound of other and unspecified parts of abdomen	0.710	0.290
S08 Traumatic amputation of part of head	0.709	0.291
S07 Crushing injury of head	0.709	0.291
S04 Injury of cranial nerves	0.709	0.291
S03 Dislocation, sprain and strain of joints and ligaments of head	0.709	0.291
S32.0 Fracture of lumbar vertebra	0.708	0.292
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.707	0.293
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.707	0.293
I30.9 Acute pericarditis, unspecified	0.707	0.293
I46.1 Sudden cardiac death, so described	0.706	0.294
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.705	0.295
S37 Injury of urinary and pelvic organs	0.705	0.295
S36 Injury of intra-abdominal organs	0.705	0.295
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.705	0.295
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.705	0.295
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.705	0.295
I42.7 Cardiomyopathy due to drugs and other external agents	0.703	0.296
I42.6 Alcoholic cardiomyopathy	0.703	0.296
I42.5 Other restrictive cardiomyopathy	0.703	0.296
I42.4 Endocardial fibroelastosis	0.703	0.296
I42.3 Endomyocardial (eosinophilic) disease	0.703	0.296
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.703	0.297
S10 Superficial injury of neck	0.701	0.299
I07 Rheumatic tricuspid valve diseases	0.701	0.299
S02.5 Fracture of tooth	0.701	0.299
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.700	0.300
S32.7 Multiple fractures of lumbar spine and pelvis	0.700	0.300
B90-B94 Sequelae of infectious and parasitic diseases	0.699	0.301
Chapter XVI Certain conditions originating in the perinatal period	0.699	0.301
S31.4 Open wound of vagina and vulva	0.699	0.301
S19 Other and unspecified injuries of neck	0.698	0.302
I21.2 Acute transmural myocardial infarction of other sites	0.698	0.302
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.696	0.304
F60-F69 Disorders of adult personality and behaviour	0.695	0.305
I68 Cerebrovascular disorders in diseases classified elsewhere	0.695	0.305
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.695	0.305
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.694	0.306
S51.9 Open wound of forearm, part unspecified	0.693	0.307
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.692	0.307
F70-F79 Mental retardation	0.692	0.307
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.692	0.308
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.690	0.310
I64 Stroke, not specified as haemorrhage or infarction	0.690	0.310
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.689	0.311
L40.8 Other psoriasis	0.688	0.312
I45.5 Other specified heart block	0.687	0.313
I61.6 Intracerebral haemorrhage, multiple localised	0.683	0.316
I61.4 Intracerebral haemorrhage in cerebellum	0.683	0.316
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.683	0.316
S51.8 Open wound of other parts of forearm	0.682	0.318
I22.0 Subsequent myocardial infarction of anterior wall	0.682	0.318
L43 Lichen planus	0.681	0.319
S59 Other and unspecified injuries of forearm	0.681	0.319
S58 Traumatic amputation of forearm	0.681	0.319
S57 Crushing injury of forearm	0.681	0.319
S55 Injury of blood vessels at forearm level	0.681	0.319
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.680	0.320
T90.2 Sequelae of fracture of skull and facial bones	0.680	0.320
Q50-Q56 Congenital malformations of genital organs	0.679	0.321
S50.0 Contusion of elbow	0.678	0.322
I27.2 Other secondary pulmonary hypertension	0.678	0.322
S42.2 Fracture of upper end of humerus	0.678	0.322
S06.9 Intracranial injury, unspecified	0.677	0.323
S06.7 Intracranial injury with prolonged coma	0.677	0.323
S06.1 Traumatic cerebral oedema	0.677	0.323
I45.6 Preexcitation syndrome	0.677	0.323
S32.2 Fracture of coccyx	0.677	0.323
L10-L14 Bullous disorders	0.677	0.323
S02.9 Fracture of skull and facial bones, part unspecified	0.676	0.324
S02.7 Multiple fractures involving skull and facial bones	0.676	0.324
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.676	0.324
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.675	0.325
F09 Unspecified organic or symptomatic mental disorder	0.675	0.325
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.675	0.325
L53 Other erythematous conditions	0.675	0.325
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.675	0.325
A30-A49 Other bacterial diseases	0.674	0.326
F40-F48 Neurotic, stress-related and somatoform disorders	0.674	0.326
Q80-Q89 Other congenital malformations	0.673	0.327
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.672	0.328
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.671	0.329
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.671	0.329
S02.40 Fracture of malar and maxillary bones (closed)	0.671	0.329
S32.3 Fracture of ilium	0.671	0.329
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.670	0.330
L50 Urticaria	0.670	0.330
Chapter XXII Codes for special purposes	0.670	0.330
S67 Crushing injury of wrist and hand	0.669	0.331
S90 Superficial injury of ankle and foot	0.669	0.331
I37.1 Pulmonary valve insufficiency	0.666	0.334
S02.8 Fractures of other skull and facial bones	0.665	0.335
B18 Chronic viral hepatitis	0.664	0.336
S06.4 Epidural haemorrhage	0.663	0.337
S09.9 Unspecified injury of head	0.663	0.337
L40.5 Arthropathic psoriasis	0.663	0.337
S31.1 Open wound of abdominal wall	0.663	0.337
I25.3 Aneurysm of heart	0.661	0.339
I98 Other disorders of circulatory system in diseases classified elsewhere	0.661	0.339
S68 Traumatic amputation of wrist and hand	0.660	0.340
I49 Other cardiac arrhythmias	0.658	0.342
T92 Sequelae of injuries of upper limb	0.657	0.343
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.657	0.343
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.656	0.343
L44 Other papulosquamous disorders	0.655	0.345
L41 Parapsoriasis	0.655	0.345
L45 Papulosquamous disorders in diseases classified elsewhere	0.655	0.345
L42 Pityriasis rosea	0.655	0.345
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.655	0.345
A80-A89 Viral infections of the central nervous system	0.655	0.345
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.654	0.346
F25.9 Schizoaffective disorder, unspecified	0.654	0.346
I61.5 Intracerebral haemorrhage, intraventricular	0.653	0.347
L08 Other local infections of skin and subcutaneous tissue	0.653	0.347
S06.2 Diffuse brain injury	0.650	0.350
S61 Open wound of wrist and hand	0.650	0.350
I09 Other rheumatic heart diseases	0.648	0.352
I06 Rheumatic aortic valve diseases	0.648	0.352
F28 Other nonorganic psychotic disorders	0.647	0.353
F24 Induced delusional disorder	0.647	0.353
F21 Schizotypal disorder	0.647	0.353
X58-X59 Accidental exposure to other and unspecified factors	0.647	0.353
S02.2 Fracture of nasal bones	0.646	0.354
I05.9 Mitral valve disease, unspecified	0.646	0.354
S42.20 Fracture of upper end of humerus (closed)	0.645	0.355
I33.9 Acute endocarditis, unspecified	0.645	0.355
S32.10 Fracture of sacrum (closed)	0.644	0.356
I95.0 Idiopathic hypotension	0.644	0.356
I95.2 Hypotension due to drugs	0.644	0.356
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.643	0.356
L03.0 Cellulitis of finger and toe	0.643	0.357
L20-L30 Dermatitis and eczema	0.642	0.358
W00-W19 Falls	0.641	0.359
S01 Open wound of head	0.641	0.359
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.641	0.359
F20.0 Paranoid schizophrenia	0.640	0.359
S20-S29 Injuries to the thorax	0.640	0.360
F11 Mental and behavioural disorders due to use of opioids	0.639	0.361
S30.1 Contusion of abdominal wall	0.639	0.361
F25.0 Schizoaffective disorder, manic type	0.639	0.361
S56.5 Injury of other extensor muscle and tendon at forearm level	0.639	0.361
S51.7 Multiple open wounds of forearm	0.638	0.362
L40.4 Guttate psoriasis	0.638	0.362
L40.3 Pustulosis palmaris et plantaris	0.638	0.362
L40.2 Acrodermatitis continua	0.638	0.362
L40.1 Generalised pustular psoriasis	0.638	0.362
S09.8 Other specified injuries of head	0.636	0.364
S30.2 Contusion of external genital organs	0.634	0.366
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.633	0.366
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.633	0.366
T41 Poisoning by anaesthetics and therapeutic gases	0.633	0.366
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.633	0.366
T36 Poisoning by systemic antibiotics	0.633	0.366
F23 Acute and transient psychotic disorders	0.633	0.367
L03.8 Cellulitis of other sites	0.633	0.367
T66-T78 Other and unspecified effects of external causes	0.633	0.367
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.633	0.367
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.632	0.368
T98 Sequelae of other and unspecified effects of external causes	0.632	0.368
S92 Fracture of foot, except ankle	0.632	0.368
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.629	0.370
Q35-Q37 Cleft lip and cleft palate	0.629	0.370
Q30-Q34 Congenital malformations of the respiratory system	0.629	0.370
T46 Poisoning by agents primarily affecting the cardiovascular system	0.629	0.371
T90.5 Sequelae of intracranial injury	0.629	0.371
F25.1 Schizoaffective disorder, depressive type	0.628	0.372
S14 Injury of nerves and spinal cord at neck level	0.628	0.372
S02.6 Fracture of mandible	0.628	0.372
F05 Delirium, not induced by alcohol and other psychoactive substances	0.628	0.372
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.628	0.372
F29 Unspecified nonorganic psychosis	0.627	0.373
S02.30 Fracture of orbital floor (closed)	0.626	0.374
Q60-Q64 Congenital malformations of the urinary system	0.626	0.374
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.626	0.374
F80-F89 Disorders of psychological development	0.625	0.375
I08.0 Disorders of both mitral and aortic valves	0.625	0.375
I49.8 Other specified cardiac arrhythmias	0.625	0.375
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.624	0.376
S32.51 Fracture of pubis (open)	0.624	0.376
I23.8 Other current complications following acute myocardial infarction	0.622	0.378
T95 Sequelae of burns, corrosions and frostbite	0.622	0.378
T94 Sequelae of injuries involving multiple and unspecified body regions	0.622	0.378
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.622	0.378
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.622	0.378
I45.4 Nonspecific intraventricular block	0.621	0.379
I45.3 Trifascicular block	0.621	0.379
I45.0 Right fascicular block	0.621	0.379
B91 Sequelae of poliomyelitis	0.621	0.379
S40.0 Contusion of shoulder and upper arm	0.621	0.379
F01.8 Other vascular dementia	0.620	0.380
F01.3 Mixed cortical and subcortical vascular dementia	0.620	0.380
F01.2 Subcortical vascular dementia	0.620	0.380
F01.1 Multi-infarct dementia	0.620	0.380
F01.0 Vascular dementia of acute onset	0.620	0.380
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.619	0.381
S31.5 Open wound of other and unspecified external genital organs	0.619	0.381
S31.3 Open wound of scrotum and testes	0.619	0.381
S31.2 Open wound of penis	0.619	0.381
S31.0 Open wound of lower back and pelvis	0.619	0.381
S02.11 Fracture of base of skull (open)	0.618	0.382
T90.1 Sequelae of open wound of head	0.617	0.383
I45.8 Other specified conduction disorders	0.617	0.383
A40 Streptococcal septicaemia	0.617	0.383
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.616	0.384
S17 Crushing injury of neck	0.616	0.384
S15 Injury of blood vessels at neck level	0.616	0.384
S11 Open wound of neck	0.616	0.384
S18 Traumatic amputation at neck level	0.616	0.384
S16 Injury of muscle and tendon at neck level	0.616	0.384
S32.40 Fracture of acetabulum (closed)	0.614	0.386
L04 Acute lymphadenitis	0.614	0.386
L01 Impetigo	0.614	0.386
L00 Staphylococcal scalded skin syndrome	0.614	0.386
S91 Open wound of ankle and foot	0.612	0.387
S06.30 Focal brain injury (without open intracranial wound)	0.611	0.389
L51 Erythema multiforme	0.611	0.389
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.610	0.390
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.609	0.391
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.609	0.391
F06.6 Organic emotionally labile [asthenic] disorder	0.609	0.391
F06.5 Organic dissociative disorder	0.609	0.391
F06.4 Organic anxiety disorder	0.609	0.391
F06.3 Organic mood [affective] disorders	0.609	0.391
F06.2 Organic delusional [schizophrenia-like] disorder	0.609	0.391
F06.1 Organic catatonic disorder	0.609	0.391
F06.0 Organic hallucinosis	0.609	0.391
F22.0 Delusional disorder	0.609	0.391
S99 Other and unspecified injuries of ankle and foot	0.609	0.391
S98 Traumatic amputation of ankle and foot	0.609	0.391
S97 Crushing injury of ankle and foot	0.609	0.391
S96 Injury of muscle and tendon at ankle and foot level	0.609	0.391
S95 Injury of blood vessels at ankle and foot level	0.609	0.391
S94 Injury of nerves at ankle and foot level	0.609	0.391
F99-F99 Unspecified mental disorder	0.609	0.391
S48 Traumatic amputation of shoulder and upper arm	0.607	0.393
S45 Injury of blood vessels at shoulder and upper arm level	0.607	0.393
S44 Injury of nerves at shoulder and upper arm level	0.607	0.393
S41 Open wound of shoulder and upper arm	0.607	0.393
S47 Crushing injury of shoulder and upper arm	0.607	0.393
S46 Injury of muscle and tendon at shoulder and upper arm level	0.606	0.394
I45.9 Conduction disorder, unspecified	0.605	0.395
S12 Fracture of neck	0.605	0.395
I99 Other and unspecified disorders of circulatory system	0.604	0.396
F31 Bipolar affective disorder	0.603	0.397
I20 Angina pectoris	0.603	0.397
T39.0 Salicylates	0.602	0.398
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.601	0.399
I36.8 Other nonrheumatic tricuspid valve disorders	0.601	0.399
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.601	0.399
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.601	0.399
I60.8 Other subarachnoid haemorrhage	0.601	0.399
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.601	0.399
I60.5 Subarachnoid haemorrhage from vertebral artery	0.601	0.399
I60.4 Subarachnoid haemorrhage from basilar artery	0.601	0.399
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.601	0.399
T91 Sequelae of injuries of neck and trunk	0.601	0.399
B18.2 Chronic viral hepatitis C	0.600	0.400
I30.8 Other forms of acute pericarditis	0.594	0.405
I30.1 Infective pericarditis	0.594	0.405
I30.0 Acute nonspecific idiopathic pericarditis	0.594	0.405
Q00-Q07 Congenital malformations of the nervous system	0.594	0.406
S61.7 Multiple open wounds of wrist and hand	0.594	0.406
F30 Manic episode	0.592	0.408
Q66 Congenital deformities of feet	0.591	0.409
S49 Other and unspecified injuries of shoulder and upper arm	0.590	0.410
Q65 Congenital deformities of hip	0.590	0.410
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.589	0.410
L54 Erythema in diseases classified elsewhere	0.589	0.410
L52 Erythema nodosum	0.589	0.410
S65 Injury of blood vessels at wrist and hand level	0.589	0.411
S10.9 Superficial injury of neck, part unspecified	0.588	0.411
L03.1 Cellulitis of other parts of limb	0.588	0.412
S00.3 Superficial injury of nose	0.588	0.412
I95.8 Other hypotension	0.587	0.413
I62.1 Nontraumatic extradural haemorrhage	0.587	0.413
Y52 Agents primarily affecting the cardiovascular system	0.587	0.413
S09.7 Multiple injuries of head	0.587	0.413
S09.2 Traumatic rupture of ear drum	0.587	0.413
S09.1 Injury of muscle and tendon of head	0.587	0.413
S09.0 Injury of blood vessels of head, not elsewhere classified	0.587	0.413
I51 Complications and ill-defined descriptions of heart disease	0.586	0.414
V80-V89 Other land transport accidents	0.586	0.414
T31 Burns classified according to extent of body surface involved	0.586	0.414
W07 Fall involving chair	0.585	0.415
S05.9 Injury of eye and orbit, part unspecified	0.585	0.415
B20-B24 Human immunodeficiency virus [HIV] disease	0.584	0.416
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.583	0.417
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.582	0.417
I45.2 Bifascicular block	0.582	0.418
I05.1 Rheumatic mitral insufficiency	0.582	0.418
T45.5 Anticoagulants	0.581	0.419
L05 Pilonidal cyst	0.581	0.419
S53.3 Traumatic rupture of ulnar collateral ligament	0.580	0.420
B99-B99 Other infectious diseases	0.580	0.420
B85-B89 Pediculosis, acariasis and other infestations	0.580	0.420
B50-B64 Protozoal diseases	0.580	0.420
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.580	0.420
A75-A79 Rickettsioses	0.580	0.420
A70-A74 Other diseases caused by chlamydiae	0.580	0.420
A65-A69 Other spirochaetal diseases	0.580	0.420
A20-A28 Certain zoonotic bacterial diseases	0.580	0.420
A15-A19 Tuberculosis	0.580	0.420
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.579	0.421
F02.3 Dementia in Parkinson's disease	0.579	0.421
T21 Burn and corrosion of trunk	0.579	0.421
S30.0 Contusion of lower back and pelvis	0.578	0.421
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.578	0.422
S02.00 Fracture of vault of skull (closed)	0.578	0.422
I37.9 Pulmonary valve disorder, unspecified	0.577	0.422
I37.8 Other pulmonary valve disorders	0.577	0.422
I37.2 Pulmonary valve stenosis with insufficiency	0.577	0.422
I37.0 Pulmonary valve stenosis	0.577	0.422
Y51 Drugs primarily affecting the autonomic nervous system	0.577	0.423
F43 Reaction to severe stress, and adjustment disorders	0.577	0.423
L40.0 Psoriasis vulgaris	0.577	0.423
T90.9 Sequelae of unspecified injury of head	0.576	0.424
S06.80 Other intracranial injuries (without open intracranial wound)	0.575	0.425
F20.9 Schizophrenia, unspecified	0.575	0.425
I28 Other diseases of pulmonary vessels	0.575	0.425
T17 Foreign body in respiratory tract	0.574	0.425
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.573	0.427
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.573	0.427
Y95 Nosocomial condition	0.573	0.427
F25.8 Other schizoaffective disorders	0.572	0.428
F25.2 Schizoaffective disorder, mixed type	0.572	0.428
S01.7 Multiple open wounds of head	0.572	0.428
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.571	0.429
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.571	0.429
T39.4 Antirheumatics, not elsewhere classified	0.571	0.429
T39.2 Pyrazolone derivatives	0.571	0.429
Q43 Other congenital malformations of intestine	0.570	0.430
S00.0 Superficial injury of scalp	0.567	0.433
S93.0 Dislocation of ankle joint	0.567	0.433
T39.1 4-Aminophenol derivatives	0.567	0.433
A40.9 Streptococcal septicaemia, unspecified	0.567	0.433
S06.0 Concussion	0.566	0.434
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.565	0.435
S54.0 Injury of ulnar nerve at forearm level	0.564	0.436
Y00-Y09 Assault	0.563	0.437
Chapter XV Pregnancy, childbirth and the puerperium	0.563	0.437
S02.41 Fracture of malar and maxillary bones (open)	0.563	0.437
T90.8 Sequelae of other specified injuries of head	0.563	0.437
T90.3 Sequelae of injury of cranial nerves	0.563	0.437
T90.0 Sequelae of superficial injury of head	0.563	0.437
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.562	0.438
X60-X84 Intentional self-harm	0.561	0.439

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations