TreeWAS – Variant ID: rs1207421

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M54 Dorsalgia	0.525	0.475	0.000
M54.56 Low back pain (Lumbar region)	0.519	0.481	0.000
M54.9 Dorsalgia, unspecified	0.510	0.490	0.000
M54.5 Low back pain	0.510	0.490	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.501	0.499	0.000
M50-M54 Other dorsopathies	0.494	0.506	0.000
M54.3 Sciatica	0.465	0.535	0.000
M54.1 Radiculopathy	0.457	0.543	0.000
M54.39 Sciatica (Site unspecified)	0.443	0.557	0.000
M54.4 Lumbago with sciatica	0.440	0.560	0.000
M51 Other intervertebral disk disorders	0.432	0.568	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.430	0.570	0.000
M51.2 Other specified intervertebral disk displacement	0.418	0.582	0.000
M54.12 Radiculopathy (Cervical region)	0.405	0.595	0.000
M50 Cervical disk disorders	0.402	0.598	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.401	0.599	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.397	0.603	0.000
M45-M49 Spondylopathies	0.393	0.607	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.388	0.612	0.000
M53 Other dorsopathies, not elsewhere classified	0.381	0.619	0.000
M54.55 Low back pain (Thoracolumbar region)	0.377	0.623	0.000
M54.0 Panniculitis affecting regions of neck and back	0.376	0.624	0.000
M48 Other spondylopathies	0.376	0.624	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.375	0.625	0.000
M54.8 Other dorsalgia	0.372	0.627	0.000
M54.52 Low back pain-Cervical	0.369	0.630	0.000
M50.3 Other cervical disk degeneration	0.369	0.631	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.366	0.634	0.000
M54.53 Low back pain-Cervicothoracic	0.365	0.634	0.000
M54.51 Low back pain-Occipit-atl-axl	0.365	0.634	0.000
M48.0 Spinal stenosis	0.361	0.639	0.000
M54.54 Low back pain-Thoracic	0.354	0.645	0.000
M47 Spondylosis	0.353	0.647	0.000
M54.2 Cervicalgia	0.352	0.648	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.350	0.650	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.348	0.651	0.000
M54.30 Sciatica (Multiple sites in spine)	0.348	0.652	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.348	0.652	0.000
M60-M63 Disorders of muscles	0.348	0.652	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.346	0.654	0.000
M54.19 Radiculopathy (Site unspecified)	0.346	0.654	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.345	0.655	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.343	0.657	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.343	0.657	0.000
M54.14 Radiculopathy (Thoracic region)	0.342	0.658	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.337	0.663	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.336	0.664	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.335	0.665	0.000
M54.35 Sciatica (Thoracolumbar region)	0.333	0.667	0.000
M54.34 Sciatica-Thoracic	0.333	0.667	0.000
M54.33 Sciatica-Cervicothoracic	0.333	0.667	0.000
M54.32 Sciatica-Cervical	0.333	0.667	0.000
M54.31 Sciatica-Occipit-atl-axl	0.333	0.667	0.000
M80-M85 Disorders of bone density and structure	0.333	0.667	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.328	0.672	0.000
M65-M68 Disorders of synovium and tendon	0.328	0.672	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.328	0.672	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.328	0.672	0.000
M51.4 Schmorl's nodes	0.326	0.673	0.000
M46 Other inflammatory spondylopathies	0.326	0.674	0.000
M47.9 Spondylosis, unspecified	0.326	0.674	0.000
M86-M90 Other osteopathies	0.324	0.676	0.000
M48.09 Spinal stenosis (Site unspecified)	0.322	0.678	0.000
M00-M03 Infectious arthropathies	0.319	0.681	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.318	0.682	0.000
M91-M94 Chondropathies	0.318	0.682	0.000
M50.2 Other cervical disk displacement	0.317	0.683	0.000
M50.0 Cervical disk disorder with myelopathy	0.317	0.683	0.000
M47.2 Other spondylosis with radiculopathy	0.316	0.684	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.316	0.684	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.316	0.684	0.000
M54.44 Lumbago with sciatica-Thoracic	0.316	0.684	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.316	0.684	0.000
M54.42 Lumbago with sciatica-Cervical	0.316	0.684	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.316	0.684	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.316	0.684	0.000
M54.50 Low back pain (Multiple sites in spine)	0.315	0.685	0.000
M54.6 Pain in thoracic spine	0.311	0.688	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.310	0.690	0.000
M51.3 Other specified intervertebral disk degeneration	0.309	0.691	0.000
M48.8 Other specified spondylopathies	0.304	0.696	0.000
M62 Other disorders of muscle	0.302	0.698	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.301	0.698	0.000
M05-M14 Inflammatory polyarthropathies	0.296	0.704	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.296	0.704	0.000
M85 Other disorders of bone density and structure	0.294	0.706	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.292	0.708	0.000
M48.9 Spondylopathy, unspecified	0.292	0.708	0.000
M84 Disorders of continuity of bone	0.289	0.711	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.288	0.712	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.288	0.712	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.287	0.713	0.000
M87 Osteonecrosis	0.284	0.716	0.000
M53.9 Dorsopathy, unspecified	0.283	0.717	0.000
M65 Synovitis and tenosynovitis	0.283	0.717	0.000
M54.37 Sciatica (Lumbosacral region)	0.281	0.719	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.281	0.719	0.000
M54.86 Other dorsalgia (Lumbar region)	0.280	0.719	0.000
M53.8 Other specified dorsopathies	0.279	0.721	0.000
M07 Psoriatic and enteropathic arthropathies	0.278	0.722	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.275	0.725	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.274	0.726	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.274	0.726	0.000
M53.1 Cervicobrachial syndrome	0.273	0.726	0.000
M53.0 Cervicocranial syndrome	0.273	0.726	0.000
M60 Myositis	0.273	0.726	0.000
M45 Ankylosing spondylitis	0.273	0.727	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.272	0.728	0.000
M54.84 Other dorsalgia (Thoracic region)	0.270	0.729	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.270	0.730	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.270	0.730	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.270	0.730	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.270	0.730	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.270	0.730	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.270	0.730	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.270	0.730	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.270	0.730	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.270	0.730	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.270	0.730	0.000
M48.4 Fatigue fracture of vertebra	0.270	0.730	0.000
M48.3 Traumatic spondylopathy	0.270	0.730	0.000
M48.2 Kissing spine	0.270	0.730	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.270	0.730	0.000
M49 Spondylopathies in diseases classified elsewhere	0.268	0.732	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.267	0.733	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.267	0.733	0.000
M54.82 Other dorsalgia (Cervical region)	0.267	0.733	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.267	0.733	0.000
M54.89 Other dorsalgia (Site unspecified)	0.266	0.734	0.000
M07.3 Other psoriatic arthropathies	0.266	0.734	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.264	0.736	0.000
M50.9 Cervical disk disorder, unspecified	0.263	0.737	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.262	0.738	0.000
M92 Other juvenile osteochondrosis	0.261	0.739	0.000
M85.8 Other specified disorders of bone density and structure	0.260	0.740	0.000
M54.16 Radiculopathy (Lumbar region)	0.260	0.740	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.260	0.740	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.260	0.740	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.259	0.741	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.259	0.741	0.000
M47.1 Other spondylosis with myelopathy	0.259	0.741	0.000
M46.0 Spinal enthesopathy	0.256	0.744	0.000
M53.2 Spinal instabilities	0.255	0.745	0.000
M00 Pyogenic arthritis	0.255	0.745	0.000
M54.36 Sciatica (Lumbar region)	0.254	0.745	0.000
M10 Gout	0.254	0.746	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.253	0.747	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.253	0.747	0.000
M48.04 Spinal stenosis (Thoracic region)	0.252	0.748	0.000
M54.27 Cervicalgia-Lumbosacral	0.252	0.748	0.000
M54.26 Cervicalgia-Lumbar	0.252	0.748	0.000
M54.25 Cervicalgia-Thoracolumbar	0.252	0.748	0.000
M54.24 Cervicalgia-Thoracic	0.252	0.748	0.000
M54.20 Cervicalgia-Mult site	0.252	0.748	0.000
M84.0 Malunion of fracture	0.252	0.748	0.000
M93 Other osteochondropathies	0.251	0.748	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.251	0.749	0.000
M66 Spontaneous rupture of synovium and tendon	0.250	0.750	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.250	0.750	0.000
M61 Calcification and ossification of muscle	0.250	0.750	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.249	0.751	0.000
M54.29 Cervicalgia-Site unspe	0.249	0.751	0.000
M46.2 Osteomyelitis of vertebra	0.247	0.752	0.000
M87.2 Osteonecrosis due to previous trauma	0.247	0.753	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.246	0.754	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.245	0.755	0.000
M65.1 Other infective (teno)synovitis	0.244	0.756	0.000
M40-M43 Deforming dorsopathies	0.243	0.757	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.243	0.757	0.000
M50.8 Other cervical disk disorders	0.243	0.757	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.242	0.757	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.242	0.758	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.241	0.759	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.241	0.759	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.240	0.760	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.240	0.760	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.240	0.760	0.000
M51.9 Intervertebral disk disorder, unspecified	0.239	0.760	0.000
M02 Reactive arthropathies	0.239	0.760	0.000
M54.57 Low back pain (Lumbosacral region)	0.236	0.764	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.236	0.764	0.000
M60.9 Myositis, unspecified	0.236	0.764	0.000
M80 Osteoporosis with pathological fracture	0.235	0.764	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.235	0.765	0.000
M88 Paget's disease of bone [osteitis deformans]	0.234	0.766	0.000
M46.8 Other specified inflammatory spondylopathies	0.234	0.766	0.000
M46.5 Other infective spondylopathies	0.234	0.766	0.000
M54.22 Cervicalgia (Cervical region)	0.234	0.766	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.234	0.766	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.234	0.766	0.000
M83 Adult osteomalacia	0.233	0.766	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.232	0.768	0.000
M62.6 Muscle strain	0.231	0.769	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.231	0.769	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.230	0.770	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.230	0.770	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.229	0.771	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.229	0.771	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.228	0.772	0.000
M89 Other disorders of bone	0.228	0.772	0.000
M10.9 Gout, unspecified	0.227	0.773	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.227	0.773	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.227	0.773	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.227	0.773	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.227	0.773	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.227	0.773	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.227	0.773	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.226	0.773	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.226	0.773	0.000
M62.0 Diastasis of muscle	0.226	0.774	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.224	0.776	0.000
M12 Other specific arthropathies	0.224	0.776	0.000
M62.2 Ischaemic infarction of muscle	0.224	0.776	0.000
M86 Osteomyelitis	0.224	0.776	0.000
M14 Arthropathies in other diseases classified elsewhere	0.224	0.776	0.000
M54.69 Pain in thoracic spine-Site unspe	0.223	0.776	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.223	0.776	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.223	0.776	0.000
M54.66 Pain in thoracic spine-Lumbar	0.223	0.776	0.000
M54.62 Pain in thoracic spine-Cervical	0.223	0.776	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.223	0.776	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.223	0.776	0.000
M84.4 Pathological fracture, not elsewhere classified	0.223	0.777	0.000
M85.2 Hyperostosis of skull	0.223	0.777	0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.222	0.778	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.222	0.778	0.000
M85.0 Fibrous dysplasia (monostotic)	0.222	0.778	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.221	0.779	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.220	0.780	0.000
M08 Juvenile arthritis	0.220	0.780	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.219	0.780	0.000
M48.06 Spinal stenosis (Lumbar region)	0.219	0.781	0.000
M62.4 Contracture of muscle	0.219	0.781	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.218	0.782	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.218	0.782	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.218	0.782	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.218	0.782	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.218	0.782	0.000
M90 Osteopathies in diseases classified elsewhere	0.218	0.782	0.000
M84.8 Other disorders of continuity of bone	0.218	0.782	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.218	0.782	0.000
M62.9 Disorder of muscle, unspecified	0.217	0.783	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.217	0.783	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.217	0.783	0.000
M62.3 Immobility syndrome (paraplegic)	0.216	0.783	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.216	0.784	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.216	0.784	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.216	0.784	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.216	0.784	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.216	0.784	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.216	0.784	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.216	0.784	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.216	0.784	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.216	0.784	0.000
M53.96 Dorsopathy, unspecified (Lumbar region)	0.216	0.784	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.216	0.784	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.216	0.784	0.000
M87.9 Osteonecrosis, unspecified	0.215	0.785	0.000
M82 Osteoporosis in diseases classified elsewhere	0.214	0.786	0.000
M46.4 Discitis, unspecified	0.214	0.786	0.000
M53.82 Other specified dorsopathies (Cervical region)	0.213	0.787	0.000
M51.8 Other specified intervertebral disk disorders	0.213	0.787	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.213	0.787	0.000
M65.0 Abscess of tendon sheath	0.212	0.788	0.000
M84.3 Stress fracture, not elsewhere classified	0.212	0.788	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.211	0.789	0.000
M85.5 Aneurysmal bone cyst	0.211	0.789	0.000
M85.3 Osteitis condensans	0.211	0.789	0.000
M85.1 Skeletal fluorosis	0.211	0.789	0.000
M85.9 Disorder of bone density and structure, unspecified	0.211	0.789	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.211	0.789	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.209	0.790	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.209	0.790	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.209	0.790	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.209	0.790	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.209	0.790	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.209	0.790	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.209	0.790	0.000
M85.4 Solitary bone cyst	0.209	0.790	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.209	0.791	0.000
M11 Other crystal arthropathies	0.209	0.791	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.209	0.791	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.208	0.791	0.001
M65.2 Calcific tendinitis	0.208	0.792	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.208	0.792	0.000
M67 Other disorders of synovium and tendon	0.208	0.792	0.000
M87.1 Osteonecrosis due to drugs	0.208	0.792	0.000
M84.9 Disorder of continuity of bone, unspecified	0.208	0.792	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.208	0.792	0.000
M65.8 Other synovitis and tenosynovitis	0.207	0.792	0.000
M66.3 Spontaneous rupture of flexor tendons	0.207	0.793	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.206	0.794	0.000
M84.02 Malunion of fracture (Upper arm)	0.206	0.794	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.206	0.794	0.000
M87.3 Other secondary osteonecrosis	0.206	0.794	0.000
M89.8 Other specified disorders of bone	0.205	0.795	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.204	0.796	0.000
M93.9 Osteochondropathy, unspecified	0.204	0.796	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.204	0.796	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.204	0.796	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.204	0.796	0.000
M87.8 Other osteonecrosis	0.203	0.796	0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.203	0.797	0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.203	0.797	0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.203	0.797	0.000
M53.94 Dorsopathy, unspecified (Thoracic region)	0.203	0.797	0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.203	0.797	0.000
M53.92 Dorsopathy, unspecified (Cervical region)	0.203	0.797	0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.203	0.797	0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.203	0.797	0.000
M85.6 Other cyst of bone	0.203	0.797	0.000
M07.38 Other psoriatic arthropathies (Other)	0.202	0.798	0.000
M84.01 Malunion of fracture (Shoulder region)	0.201	0.799	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.201	0.799	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.201	0.799	0.000
M60.8 Other myositis	0.200	0.799	0.000
M53.89 Other specified dorsopathies (Site unspecified)	0.200	0.800	0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.200	0.800	0.000
M53.87 Other specified dorsopathies (Lumbosacral region)	0.200	0.800	0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.200	0.800	0.000
M53.84 Other specified dorsopathies (Thoracic region)	0.200	0.800	0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.200	0.800	0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.200	0.800	0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.200	0.800	0.000
M94 Other disorders of cartilage	0.200	0.800	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.200	0.800	0.000
M07.5 Arthropathy in ulcerative colitis	0.200	0.800	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.200	0.800	0.000
M07.2 Psoriatic spondylitis	0.200	0.800	0.000
M07.1 Arthritis mutilans	0.200	0.800	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.200	0.800	0.000
M53.99 Dorsopathy, unspecified (Site unspecified)	0.199	0.801	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.199	0.801	0.000
M07.6 Other enteropathic arthropathies	0.199	0.801	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.199	0.801	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.199	0.801	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.198	0.802	0.000
M00.9 Pyogenic arthritis, unspecified	0.197	0.803	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.197	0.803	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.196	0.803	0.000
M53.09 Cervicocranial syndrome-Site unspe	0.196	0.804	0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.196	0.804	0.000
M53.07 Cervicocranial syndrome-Lumbosacral	0.196	0.804	0.000
M53.06 Cervicocranial syndrome-Lumbar	0.196	0.804	0.000
M53.05 Cervicocranial syndrome-Thoracolumbar	0.196	0.804	0.000
M53.04 Cervicocranial syndrome-Thoracic	0.196	0.804	0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.196	0.804	0.000
M53.02 Cervicocranial syndrome (Cervical region)	0.196	0.804	0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.196	0.804	0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.196	0.804	0.000
M53.19 Cervicobrachial syndrome-Site unspe	0.196	0.804	0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.196	0.804	0.000
M53.17 Cervicobrachial syndrome-Lumbosacral	0.196	0.804	0.000
M53.16 Cervicobrachial syndrome-Lumbar	0.196	0.804	0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.196	0.804	0.000
M53.14 Cervicobrachial syndrome-Thoracic	0.196	0.804	0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.196	0.804	0.000
M53.12 Cervicobrachial syndrome (Cervical region)	0.196	0.804	0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.196	0.804	0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.196	0.804	0.000
M60.1 Interstitial myositis	0.196	0.804	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.196	0.804	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.196	0.804	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.196	0.804	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.195	0.804	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.195	0.804	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.195	0.804	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.195	0.804	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.195	0.804	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.194	0.805	0.000
M10.96 Gout, unspecified (Lower leg)	0.194	0.806	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.194	0.806	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.194	0.806	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.194	0.806	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.194	0.806	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.194	0.806	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.194	0.806	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.194	0.806	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.194	0.806	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.194	0.806	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.194	0.806	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.194	0.806	0.000
M48.29 Kissing spine (Site unspecified)	0.194	0.806	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.194	0.806	0.000
M48.27 Kissing spine (Lumbosacral region)	0.194	0.806	0.000
M48.26 Kissing spine (Lumbar region)	0.194	0.806	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.194	0.806	0.000
M48.24 Kissing spine (Thoracic region)	0.194	0.806	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.194	0.806	0.000
M48.22 Kissing spine (Cervical region)	0.194	0.806	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.194	0.806	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.194	0.806	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.194	0.806	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.194	0.806	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.194	0.806	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.194	0.806	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.194	0.806	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.194	0.806	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.194	0.806	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.194	0.806	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.194	0.806	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.194	0.806	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.194	0.806	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.194	0.806	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.194	0.806	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.194	0.806	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.194	0.806	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.194	0.806	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.194	0.806	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.194	0.806	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.194	0.806	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.194	0.806	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.193	0.807	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.193	0.807	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.193	0.807	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.192	0.807	0.000
M49.4 Neuropathic spondylopathy	0.192	0.807	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.192	0.807	0.000
M49.2 Enterobacterial spondylitis	0.192	0.807	0.000
M49.1 Brucella spondylitis	0.192	0.807	0.000
M49.0 Tuberculosis of spine	0.192	0.807	0.000
M92.2 Juvenile osteochondrosis of hand	0.192	0.808	0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.192	0.808	0.000
M84.06 Malunion of fracture (Lower leg)	0.192	0.808	0.000
M60.99 Myositis, unspecified (Site unspecified)	0.192	0.808	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.192	0.808	0.000
M99 Biomechanical lesions, not elsewhere classified	0.192	0.808	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.192	0.808	0.000
M53.86 Other specified dorsopathies (Lumbar region)	0.191	0.809	0.000
M60.0 Infective myositis	0.191	0.809	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.191	0.809	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.191	0.809	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.191	0.809	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.190	0.810	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.190	0.810	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.190	0.810	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.190	0.810	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.190	0.810	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.189	0.810	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.189	0.811	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.189	0.811	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.189	0.811	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.189	0.811	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.188	0.811	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.188	0.812	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.188	0.812	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.187	0.813	0.000
M92.5 Juvenile osteochondrosis of tibia and fibula	0.187	0.813	0.000
M92.1 Juvenile osteochondrosis of radius and ulna	0.187	0.813	0.000
M92.9 Juvenile osteochondrosis, unspecified	0.187	0.813	0.000
M92.8 Other specified juvenile osteochondrosis	0.187	0.813	0.000
M92.4 Juvenile osteochondrosis of patella	0.187	0.813	0.000
M92.3 Other juvenile osteochondrosis of upper limb	0.187	0.813	0.000
M92.0 Juvenile osteochondrosis of humerus	0.187	0.813	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.187	0.813	0.000
M84.2 Delayed union of fracture	0.187	0.813	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.186	0.813	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.186	0.813	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.186	0.813	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.186	0.814	0.000
M10.0 Idiopathic gout	0.186	0.814	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.186	0.814	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.185	0.814	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.185	0.814	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.185	0.814	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.185	0.814	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.185	0.814	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.185	0.814	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.185	0.814	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.185	0.815	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.184	0.815	0.000
M46.09 Spinal enthesopathy (Site unspecified)	0.184	0.816	0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.184	0.816	0.000
M46.07 Spinal enthesopathy (Lumbosacral region)	0.184	0.816	0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.184	0.816	0.000
M46.04 Spinal enthesopathy (Thoracic region)	0.184	0.816	0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.184	0.816	0.000
M46.02 Spinal enthesopathy (Cervical region)	0.184	0.816	0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.184	0.816	0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.184	0.816	0.000
M12.3 Palindromic rheumatism	0.184	0.816	0.000
M02.9 Reactive arthopathy, unspecified	0.183	0.816	0.000
M53.29 Spinal instabilities (Site unspecified)	0.183	0.817	0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.183	0.817	0.000
M53.25 Spinal instabilities (Thoracolumbar region)	0.183	0.817	0.000
M53.24 Spinal instabilities (Thoracic region)	0.183	0.817	0.000
M53.23 Spinal instabilities (Cervicothoracic region)	0.183	0.817	0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.183	0.817	0.000
M53.20 Spinal instabilities (Multiple sites in spine)	0.183	0.817	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.183	0.817	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.183	0.817	0.000
M10.4 Other secondary gout	0.182	0.818	0.000
M10.2 Drug-induced gout	0.182	0.818	0.000
M10.1 Lead-induced gout	0.182	0.818	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.182	0.818	0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.182	0.818	0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.182	0.818	0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.182	0.818	0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.182	0.818	0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.182	0.818	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations