TreeWAS – Variant ID: rs12126655

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.683	0.317	0.000
E03 Other hypothyroidism	0.380	0.620	0.000
E03.1 Congenital hypothyroidism without goitre	0.311	0.688	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.291	0.708	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.276	0.723	0.000
E03.5 Myxoedema coma	0.272	0.727	0.000
E03.4 Atrophy of thyroid (acquired)	0.272	0.727	0.000
E03.3 Postinfectious hypothyroidism	0.272	0.727	0.000
E03.8 Other specified hypothyroidism	0.199	0.801	0.000
E00-E07 Disorders of thyroid gland	0.125	0.875	0.000
E07 Other disorders of thyroid	0.124	0.876	0.000
E07.9 Disorder of thyroid, unspecified	0.121	0.879	0.000
E07.8 Other specified disorders of thyroid	0.105	0.895	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.090	0.910	0.000
E00 Congenital iodine-deficiency syndrome	0.090	0.910	0.000
E07.1 Dyshormogenetic goitre	0.089	0.911	0.000
E07.0 Hypersecretion of calcitonin	0.089	0.911	0.000
E06 Thyroiditis	0.083	0.917	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.076	0.924	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.065	0.935	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.065	0.935	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.065	0.935	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.065	0.935	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.065	0.935	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.065	0.935	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.065	0.935	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.065	0.935	0.000
E06.9 Thyroiditis, unspecified	0.063	0.937	0.000
E06.4 Drug-induced thyroiditis	0.059	0.941	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.059	0.941	0.000
E06.1 Subacute thyroiditis	0.059	0.941	0.000
E06.0 Acute thyroiditis	0.059	0.941	0.000
E06.5 Other chronic thyroiditis	0.058	0.941	0.000
E06.3 Autoimmune thyroiditis	0.047	0.952	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.043	0.957	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.977	0.023
E27 Other disorders of adrenal gland	0.000	0.977	0.023
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.979	0.021
H61.2 Impacted cerumen	0.020	0.980	0.000
E27.2 Addisonian crisis	0.000	0.980	0.020
E05 Thyrotoxicosis [hyperthyroidism]	0.019	0.981	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.981	0.019
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.982	0.018
E27.5 Adrenomedullary hyperfunction	0.000	0.983	0.017
E27.0 Other adrenocortical overactivity	0.000	0.983	0.017
E20-E35 Disorders of other endocrine glands	0.000	0.984	0.016
E27.9 Disorder of adrenal gland, unspecified	0.000	0.985	0.015
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.015	0.985	0.000
E26 Hyperaldosteronism	0.000	0.985	0.015
E26.0 Primary hyperaldosteronism	0.000	0.986	0.014
E05.5 Thyroid crisis or storm	0.014	0.986	0.000
E05.4 Thyrotoxicosis factitia	0.014	0.986	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.014	0.986	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.014	0.986	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.986	0.014
E34 Other endocrine disorders	0.000	0.987	0.013
E04 Other non-toxic goitre	0.013	0.987	0.000
E23.0 Hypopituitarism	0.000	0.987	0.013
E20 Hypoparathyroidism	0.000	0.987	0.012
E21.3 Hyperparathyroidism, unspecified	0.000	0.988	0.012
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.012	0.988	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.988	0.012
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.012	0.988	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.988	0.012
E25 Adrenogenital disorders	0.000	0.988	0.012
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.988	0.012
E32 Diseases of thymus	0.000	0.988	0.012
E31 Polyglandular dysfunction	0.000	0.988	0.012
E30 Disorders of puberty, not elsewhere classified	0.000	0.988	0.012
E34.8 Other specified endocrine disorders	0.000	0.988	0.012
M23.8 Other internal derangements of knee	0.011	0.989	0.000
E22 Hyperfunction of pituitary gland	0.000	0.989	0.011
E26.8 Other hyperaldosteronism	0.000	0.989	0.011
E26.1 Secondary hyperaldosteronism	0.000	0.989	0.011
E29 Testicular dysfunction	0.000	0.989	0.011
D48.5 Skin	0.010	0.990	0.000
Q63.0 Accessory kidney	0.010	0.990	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.990	0.010
E23.2 Diabetes insipidus	0.000	0.990	0.010
E23.7 Disorder of pituitary gland, unspecified	0.000	0.990	0.010
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.990	0.010
E23.1 Drug-induced hypopituitarism	0.000	0.990	0.010
E34.5 Androgen resistance syndrome	0.000	0.990	0.010
E34.4 Constitutional tall stature	0.000	0.990	0.010
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.990	0.010
E34.1 Other hypersecretion of intestinal hormones	0.000	0.990	0.010
E04.8 Other specified non-toxic goitre	0.010	0.990	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.010	0.990	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.990	0.009
G50.0 Trigeminal neuralgia	0.010	0.990	0.000
E24 Cushing's syndrome	0.000	0.990	0.009
D46.9 Myelodysplastic syndrome, unspecified	0.009	0.991	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.009	0.991	0.000
E22.1 Hyperprolactinaemia	0.000	0.991	0.009
E20.8 Other hypoparathyroidism	0.000	0.991	0.009
E20.1 Pseudohypoparathyroidism	0.000	0.991	0.009
E20.0 Idiopathic hypoparathyroidism	0.000	0.991	0.009
E04.0 Non-toxic diffuse goitre	0.009	0.991	0.000
E05.8 Other thyrotoxicosis	0.009	0.991	0.000
E34.3 Short stature, not elsewhere classified	0.000	0.991	0.009
E21.4 Other specified disorders of parathyroid gland	0.000	0.991	0.009
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.991	0.009
E25.9 Adrenogenital disorder, unspecified	0.000	0.991	0.008
E25.8 Other adrenogenital disorders	0.000	0.991	0.008
M23.87 Other internal derangements of knee (Capsular ligament)	0.009	0.991	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.009	0.991	0.000
E30.9 Disorder of puberty, unspecified	0.000	0.991	0.008
E30.8 Other disorders of puberty	0.000	0.991	0.008
E30.1 Precocious puberty	0.000	0.991	0.008
E30.0 Delayed puberty	0.000	0.991	0.008
E31.9 Polyglandular dysfunction, unspecified	0.000	0.991	0.008
E31.8 Other polyglandular dysfunction	0.000	0.991	0.008
E31.1 Polyglandular hyperfunction	0.000	0.991	0.008
E31.0 Autoimmune polyglandular failure	0.000	0.991	0.008
E32.9 Disease of thymus, unspecified	0.000	0.991	0.008
E32.8 Other diseases of thymus	0.000	0.991	0.008
E32.1 Abscess of thymus	0.000	0.991	0.008
E32.0 Persistent hyperplasia of thymus	0.000	0.991	0.008
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.991	0.008
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.991	0.008
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.991	0.008
H61 Other disorders of external ear	0.008	0.992	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.008	0.992	0.000
E21.2 Other hyperparathyroidism	0.000	0.992	0.008
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.992	0.008
E22.8 Other hyperfunction of pituitary gland	0.000	0.992	0.008
E22.0 Acromegaly and pituitary gigantism	0.000	0.992	0.008
E28 Ovarian dysfunction	0.000	0.992	0.008
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.008	0.992	0.000
E29.8 Other testicular dysfunction	0.000	0.992	0.008
E29.0 Testicular hyperfunction	0.000	0.992	0.008
H61.3 Acquired stenosis of external ear canal	0.008	0.992	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.992	0.007
E23.6 Other disorders of pituitary gland	0.000	0.992	0.007
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.992	0.007
E24.0 Pituitary-dependent Cushing's disease	0.000	0.993	0.007
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.007	0.993	0.000
E29.1 Testicular hypofunction	0.000	0.993	0.007
H61.8 Other specified disorders of external ear	0.007	0.993	0.000
E24.8 Other Cushing's syndrome	0.000	0.993	0.007
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.993	0.007
E24.3 Ectopic ACTH syndrome	0.000	0.993	0.007
E24.1 Nelson's syndrome	0.000	0.993	0.007
Q63 Other congenital malformations of kidney	0.007	0.993	0.000
E21.0 Primary hyperparathyroidism	0.000	0.993	0.007
H53.1 Subjective visual disturbances	0.000	0.993	0.007
D46 Myelodysplastic syndromes	0.007	0.993	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.993	0.007
H61.9 Disorder of external ear, unspecified	0.007	0.993	0.000
E34.0 Carcinoid syndrome	0.000	0.993	0.006
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.006	0.994	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.006	0.994	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.994	0.006
E28.8 Other ovarian dysfunction	0.000	0.994	0.006
E28.1 Androgen excess	0.000	0.994	0.006
E28.0 Oestrogen excess	0.000	0.994	0.006
D46.1 Refractory anaemia with sideroblasts	0.006	0.994	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.994	0.006
Q66.8 Other congenital deformities of feet	0.006	0.994	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.994	0.006
N90.6 Hypertrophy of vulva	0.006	0.994	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.006	0.994	0.000
D46.4 Refractory anaemia, unspecified	0.006	0.994	0.000
Q63.8 Other specified congenital malformations of kidney	0.006	0.994	0.000
S72.30 Fracture of shaft of femur (closed)	0.006	0.994	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.994	0.005
D46.0 Refractory anaemia without sideroblasts, so stated	0.005	0.994	0.000
Q63.3 Hyperplastic and giant kidney	0.005	0.995	0.000
Q63.2 Ectopic kidney	0.005	0.995	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.005	0.995	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.005	0.995	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.005	0.995	0.000
Q66 Congenital deformities of feet	0.005	0.995	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.995	0.005
E04.1 Non-toxic single thyroid nodule	0.005	0.995	0.000
E28.3 Primary ovarian failure	0.000	0.995	0.005
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.005	0.995	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.995	0.000
D46.7 Other myelodysplastic syndromes	0.005	0.995	0.000
E05.9 Thyrotoxicosis, unspecified	0.005	0.995	0.000
Q25.4 Other congenital malformations of aorta	0.005	0.995	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.995	0.000
G50 Disorders of trigeminal nerve	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.004	0.995	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.995	0.000
Q67.5 Congenital deformity of spine	0.004	0.996	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.004	0.996	0.000
Q66.6 Other congenital valgus deformities of feet	0.004	0.996	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.996	0.004
Q25.1 Coarctation of aorta	0.004	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
Q66.7 Pes cavus	0.004	0.996	0.000
H61.1 Non-infective disorders of pinna	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
D48.4 Peritoneum	0.004	0.996	0.000
D46.2 Refractory anaemia with excess of blasts	0.004	0.996	0.000
Q66.0 Talipes equinovarus	0.004	0.996	0.000
M23 Internal derangement of knee	0.004	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.996	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.004	0.996	0.000
Q25.0 Patent ductus arteriosus	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.004	0.996	0.000
Q66.5 Congenital pes planus	0.004	0.996	0.000
Q66.4 Talipes calcaneovalgus	0.004	0.996	0.000
Q66.1 Talipes calcaneovarus	0.004	0.996	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.004	0.996	0.000
M23.1 Discoid meniscus (congenital)	0.004	0.996	0.000
G50.1 Atypical facial pain	0.004	0.996	0.000
M23.3 Other meniscus derangements	0.004	0.996	0.000
Q66.2 Metatarsus varus	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
D48.6 Breast	0.004	0.996	0.000
Q44.6 Cystic disease of liver	0.004	0.996	0.000
Q05 Spina bifida	0.004	0.996	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
D48.3 Retroperitoneum	0.004	0.996	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
Q04 Other congenital malformations of brain	0.004	0.996	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.996	0.000
Q73 Reduction defects of unspecified limb	0.004	0.996	0.000
Q72 Reduction defects of lower limb	0.004	0.996	0.000
Q71 Reduction defects of upper limb	0.004	0.996	0.000
Q69 Polydactyly	0.004	0.996	0.000
Q05.9 Spina bifida, unspecified	0.004	0.996	0.000
S72.3 Fracture of shaft of femur	0.004	0.996	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q66.9 Congenital deformity of feet, unspecified	0.003	0.996	0.000
Q44.4 Choledochal cyst	0.003	0.996	0.000
D43.4 Spinal cord	0.003	0.996	0.000
Z43.1 Attention to gastrostomy	0.000	0.996	0.004
D43.2 Brain, unspecified	0.003	0.996	0.000
Q04.6 Congenital cerebral cysts	0.003	0.996	0.000
G50.9 Disorder of trigeminal nerve, unspecified	0.003	0.996	0.000
Q67.8 Other congenital deformities of chest	0.003	0.996	0.000
Q67.7 Pectus carinatum	0.003	0.996	0.000
Q67.6 Pectus excavatum	0.003	0.996	0.000
Q67.3 Plagiocephaly	0.003	0.996	0.000
Q67.2 Dolichocephaly	0.003	0.996	0.000
Q67.1 Compression facies	0.003	0.996	0.000
Q67.0 Facial asymmetry	0.003	0.996	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.003	0.997	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
M23.9 Internal derangement of knee, unspecified	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q78.0 Osteogenesis imperfecta	0.003	0.997	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.997	0.003
M23.0 Cystic meniscus	0.003	0.997	0.000
D45 Polycythaemia vera	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.003	0.997	0.000
N90.7 Vulvar cyst	0.003	0.997	0.000
S72.31 Fracture of shaft of femur (open)	0.003	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
D43.1 Brain, infratentorial	0.003	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
D44.6 Carotid body	0.003	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.003	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
Q12 Congenital lens malformations	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
E04.9 Non-toxic goitre, unspecified	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.997	0.000
Q44.2 Atresia of bile ducts	0.003	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.997	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.997	0.000
Q78.6 Multiple congenital exostoses	0.003	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.997	0.000
Q78.4 Enchondromatosis	0.003	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.997	0.000
Q78.2 Osteopetrosis	0.003	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.997	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.003	0.997	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.003	0.997	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.003	0.997	0.000
W29.9 Unspecified place	0.000	0.997	0.003
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.003	0.997	0.000
M23.37 Other meniscus derangements-Capsular lig	0.003	0.997	0.000
X78.0 Home	0.000	0.997	0.003
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q17.5 Prominent ear	0.003	0.997	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.003	0.997	0.000
H61.0 Perichondritis of external ear	0.003	0.997	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
Q70.3 Webbed toes	0.003	0.997	0.000
R49.0 Dysphonia	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
D44.4 Craniopharyngeal duct	0.003	0.997	0.000
Q70.9 Syndactyly, unspecified	0.003	0.997	0.000
Q70.4 Polysyndactyly	0.003	0.997	0.000
Q70.2 Fused toes	0.003	0.997	0.000
Q70.1 Webbed fingers	0.003	0.997	0.000
Q70.0 Fused fingers	0.003	0.997	0.000
D43.9 Central nervous system, unspecified	0.003	0.997	0.000
D43.7 Other parts of central nervous system	0.003	0.997	0.000
D43.3 Cranial nerves	0.003	0.997	0.000
G50.8 Other disorders of trigeminal nerve	0.003	0.997	0.000
Q04.9 Congenital malformation of brain, unspecified	0.003	0.997	0.000
Q04.8 Other specified congenital malformations of brain	0.003	0.997	0.000
Q04.5 Megalencephaly	0.003	0.997	0.000
Q04.4 Septo-optic dysplasia	0.003	0.997	0.000
Q04.3 Other reduction deformities of brain	0.003	0.997	0.000
Q04.2 Holoprosencephaly	0.003	0.997	0.000
Q04.1 Arhinencephaly	0.003	0.997	0.000
Q04.0 Congenital malformations of corpus callosum	0.003	0.997	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.003	0.997	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
D33.3 Cranial nerves	0.003	0.997	0.000
Q69.9 Polydactyly, unspecified	0.003	0.997	0.000
Q69.2 Accessory toe(s)	0.003	0.997	0.000
Q69.1 Accessory thumb(s)	0.003	0.997	0.000
Q69.0 Accessory finger(s)	0.003	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.997	0.000
Q71.6 Lobster-claw hand	0.003	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.997	0.000
Q72.7 Split foot	0.003	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.997	0.000
Q75.3 Macrocephaly	0.003	0.997	0.000
Q75.2 Hypertelorism	0.003	0.997	0.000
Q75.1 Craniofacial dysostosis	0.003	0.997	0.000
Q75.0 Craniosynostosis	0.003	0.997	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.997	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.997	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.997	0.000
Q77.5 Diastrophic dysplasia	0.003	0.997	0.000
Q77.4 Achondroplasia	0.003	0.997	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.997	0.000
Q77.2 Short rib syndrome	0.003	0.997	0.000
Q77.1 Thanatophoric short stature	0.003	0.997	0.000
Q77.0 Achondrogenesis	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.003	0.997	0.000
Q62.6 Malposition of ureter	0.003	0.997	0.000
Q62.4 Agenesis of ureter	0.003	0.997	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q62.2 Congenital megaloureter	0.003	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.003	0.997	0.000
Q62.0 Congenital hydronephrosis	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000
N90.0 Mild vulvar dysplasia	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
D48.7 Other specified sites	0.003	0.997	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.003	0.997	0.000
D44.3 Pituitary gland	0.003	0.997	0.000
D48.0 Bone and articular cartilage	0.003	0.997	0.000
N90.1 Moderate vulvar dysplasia	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
D38.0 Larynx	0.003	0.997	0.000
D44.7 Aortic body and other paraganglia	0.003	0.997	0.000
M23.4 Loose body in knee	0.003	0.997	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
D44.9 Endocrine gland, unspecified	0.003	0.997	0.000
D44.5 Pineal gland	0.003	0.997	0.000
D44.2 Parathyroid gland	0.003	0.997	0.000
Q11.1 Other anophthalmos	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
D44.1 Adrenal gland	0.003	0.997	0.000
Q14.1 Congenital malformation of retina	0.003	0.997	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.003	0.997	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.003	0.997	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.003	0.997	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.003	0.997	0.000
Q03.8 Other congenital hydrocephalus	0.003	0.997	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.003	0.997	0.000
Q76.5 Cervical rib	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
Q17.9 Congenital malformation of ear, unspecified	0.003	0.997	0.000
Q17.8 Other specified congenital malformations of ear	0.003	0.997	0.000
Q17.4 Misplaced ear	0.003	0.997	0.000
Q17.3 Other misshapen ear	0.003	0.997	0.000
Q17.2 Microtia	0.003	0.997	0.000
Q17.1 Macrotia	0.003	0.997	0.000
Q17.0 Accessory auricle	0.003	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.003	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.003	0.997	0.000
Q76.7 Congenital malformation of sternum	0.003	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.003	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.003	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
Q52.5 Fusion of labia	0.003	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.003	0.997	0.000
M23.07 Cystic meniscus-Capsular lig	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations