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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12257077
log Bayes Factor = 9.63273
Chromosome 10   position 6,071,545  (GRCh37) Explore rs12257077 on Ensembl!
Variant rs12257077 is part of Cluster X0074

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
J09-J18 Influenza and pneumonia
0.991 0.009 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.991 0.009 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.990 0.010 0.000
J40-J47 Chronic lower respiratory diseases
0.987 0.013 0.000
J45 Asthma
0.984 0.016 0.000
G35 Multiple sclerosis
0.984 0.016 0.000
Z50 Care involving use of rehabilitation procedures
0.983 0.017 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.983 0.017 0.000
J45.9 Asthma, unspecified
0.983 0.017 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.982 0.018 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.980 0.020 0.000
Z50.1 Other physical therapy
0.980 0.020 0.000
J18 Pneumonia, organism unspecified
0.977 0.023 0.000
E00-E07 Disorders of thyroid gland
0.976 0.024 0.000
J18.1 Lobar pneumonia, unspecified
0.965 0.035 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.962 0.038 0.000
M05-M14 Inflammatory polyarthropathies
0.959 0.041 0.000
S40-S49 Injuries to the shoulder and upper arm
0.952 0.048 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.949 0.051 0.000
V10-V19 Pedal cyclist injured in transport accident
0.945 0.055 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.933 0.067 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.929 0.071 0.000
E20-E35 Disorders of other endocrine glands
0.923 0.077 0.000
Chapter VII Diseases of the eye and adnexa
0.922 0.078 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.920 0.080 0.000
Z41 Procedures for purposes other than remedying health state
0.919 0.081 0.000
L03 Cellulitis
0.917 0.083 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.917 0.083 0.000
G30-G32 Other degenerative diseases of the nervous system
0.910 0.090 0.000
Z60 Problems related to social environment
0.910 0.090 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.909 0.091 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.908 0.092 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.903 0.097 0.000
M20-M25 Other joint disorders
0.894 0.106 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.894 0.106 0.000
M15-M19 Arthrosis
0.894 0.106 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.893 0.107 0.000
M91-M94 Chondropathies
0.891 0.109 0.000
L03.0 Cellulitis of finger and toe
0.891 0.109 0.000
H53-H54 Visual disturbances and blindness
0.888 0.112 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.887 0.113 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.884 0.116 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.883 0.117 0.000
T93 Sequelae of injuries of lower limb
0.883 0.117 0.000
M06 Other rheumatoid arthritis
0.882 0.118 0.000
M13 Other arthritis
0.878 0.122 0.000
H54 Blindness and low vision
0.877 0.123 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.874 0.126 0.000
Z60.2 Living alone
0.872 0.128 0.000
M80-M85 Disorders of bone density and structure
0.868 0.132 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.868 0.132 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.867 0.133 0.000
H55-H59 Other disorders of eye and adnexa
0.866 0.134 0.000
L03.3 Cellulitis of trunk
0.862 0.138 0.000
V18.0 Driver injured in nontraffic accident
0.862 0.138 0.000
Z02 Examination and encounter for administrative purposes
0.857 0.143 0.000
M18 Arthrosis of first carpometacarpal joint
0.856 0.144 0.000
E04 Other non-toxic goitre
0.853 0.147 0.000
E50-E64 Other nutritional deficiencies
0.851 0.149 0.000
T92 Sequelae of injuries of upper limb
0.849 0.151 0.000
J90-J94 Other diseases of pleura
0.849 0.151 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.848 0.152 0.000
W00-W19 Falls
0.842 0.158 0.000
Z63 Other problems related to primary support group, including family circumstances
0.842 0.158 0.000
E05.9 Thyrotoxicosis, unspecified
0.840 0.160 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.840 0.160 0.000
Y86 Sequelae of other accidents
0.834 0.166 0.000
M13.9 Arthritis, unspecified
0.831 0.169 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.829 0.171 0.000
M06.9 Rheumatoid arthritis, unspecified
0.829 0.171 0.000
Z01.6 Radiological examination, not elsewhere classified
0.826 0.174 0.000
E03 Other hypothyroidism
0.826 0.174 0.000
L50-L54 Urticaria and erythema
0.825 0.175 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.823 0.176 0.000
H54.7 Unspecified visual loss
0.823 0.177 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.822 0.178 0.000
H54.9 Unspecified visual impairment (binocular)
0.821 0.179 0.000
Z50.2 Alcohol rehabilitation
0.821 0.179 0.000
Z01.8 Other specified special examinations
0.817 0.183 0.000
M25 Other joint disorders, not elsewhere classified
0.817 0.183 0.000
G40-G47 Episodic and paroxysmal disorders
0.815 0.185 0.000
S10-S19 Injuries to the neck
0.815 0.185 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.814 0.186 0.000
G70-G73 Diseases of myoneural junction and muscle
0.814 0.186 0.000
Z02.8 Other examinations for administrative purposes
0.813 0.187 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.811 0.189 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.810 0.190 0.000
W50-W64 Exposure to animate mechanical forces
0.806 0.194 0.000
S90-S99 Injuries to the ankle and foot
0.805 0.195 0.000
G30 Alzheimer's disease
0.802 0.198 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.801 0.199 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.801 0.199 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.798 0.202 0.000
G90-G99 Other disorders of the nervous system
0.797 0.203 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.795 0.205 0.000
J18.0 Bronchopneumonia, unspecified
0.794 0.206 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.793 0.207 0.000
E04.2 Non-toxic multinodular goitre
0.793 0.207 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.793 0.207 0.000
M05 Seropositive rheumatoid arthritis
0.792 0.208 0.000
H10-H13 Disorders of conjunctiva
0.792 0.208 0.000
H59.8 Other postprocedural disorders of eye and adnexa
0.791 0.209 0.000
S40 Superficial injury of shoulder and upper arm
0.791 0.209 0.000
M21 Other acquired deformities of limbs
0.790 0.210 0.000
Z50.8 Care involving use of rehabilitation procedures
0.790 0.210 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.790 0.210 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.788 0.212 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.787 0.213 0.000
M81 Osteoporosis without pathological fracture
0.787 0.213 0.000
Y57 Other and unspecified drugs and medicaments
0.785 0.215 0.000
S20-S29 Injuries to the thorax
0.785 0.215 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.779 0.221 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.778 0.222 0.000
J42 Unspecified chronic bronchitis
0.777 0.223 0.000
Z49 Care involving dialysis
0.775 0.225 0.000
V40-V49 Car occupant injured in transport accident
0.774 0.225 0.000
G40 Epilepsy
0.774 0.226 0.000
M86-M90 Other osteopathies
0.773 0.227 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.773 0.227 0.000
M94 Other disorders of cartilage
0.773 0.227 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.772 0.228 0.000
E10-E14 Diabetes mellitus
0.772 0.228 0.000
Z59 Problems related to housing and economic circumstances
0.771 0.229 0.000
E06 Thyroiditis
0.770 0.229 0.000
G20-G26 Extrapyramidal and movement disorders
0.770 0.230 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.770 0.230 0.000
Chapter XXII Codes for special purposes
0.766 0.234 0.000
E53 Deficiency of other B group vitamins
0.766 0.234 0.000
X20-X29 Contact with venomous animals and plants
0.764 0.235 0.000
M13.94 Arthritis, unspecified (Hand)
0.762 0.238 0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.762 0.238 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.761 0.239 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.760 0.240 0.000
Y00-Y09 Assault
0.760 0.240 0.000
J60-J70 Lung diseases due to external agents
0.758 0.242 0.000
D60-D64 Aplastic and other anaemias
0.755 0.245 0.000
M60-M63 Disorders of muscles
0.755 0.245 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.754 0.246 0.000
T79-T79 Certain early complications of trauma
0.752 0.248 0.000
M40-M43 Deforming dorsopathies
0.751 0.249 0.000
Z50.5 Speech therapy
0.750 0.250 0.000
W07 Fall involving chair
0.750 0.250 0.000
Z48 Other surgical follow-up care
0.749 0.251 0.000
E21.0 Primary hyperparathyroidism
0.749 0.251 0.000
J10 Influenza due to identified influenza virus
0.746 0.254 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.745 0.255 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.744 0.256 0.000
J14 Pneumonia due to Haemophilus influenzae
0.743 0.257 0.000
M22 Disorders of patella
0.741 0.259 0.000
D69 Purpura and other haemorrhagic conditions
0.738 0.262 0.000
L05 Pilonidal cyst
0.737 0.263 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.736 0.264 0.000
Z46 Fitting and adjustment of other devices
0.736 0.264 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.731 0.269 0.000
S70-S79 Injuries to the hip and thigh
0.730 0.270 0.000
J93 Pneumothorax
0.729 0.271 0.000
H54.0 Blindness, both eyes
0.729 0.271 0.000
J40 Bronchitis, not specified as acute or chronic
0.727 0.273 0.000
M25.4 Effusion of joint
0.727 0.273 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.725 0.275 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.724 0.275 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.724 0.276 0.000
G30.9 Alzheimer's disease, unspecified
0.724 0.276 0.000
Z54 Convalescence
0.724 0.276 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.724 0.276 0.000
E27 Other disorders of adrenal gland
0.723 0.277 0.000
J46 Status asthmaticus
0.722 0.278 0.000
L03.9 Cellulitis, unspecified
0.722 0.278 0.000
J15.2 Pneumonia due to staphylococcus
0.720 0.280 0.000
L20-L30 Dermatitis and eczema
0.720 0.280 0.000
M35 Other systemic involvement of connective tissue
0.719 0.281 0.000
J43 Emphysema
0.719 0.281 0.000
Y40 Systemic antibiotics
0.718 0.282 0.000
M81.9 Osteoporosis, unspecified
0.718 0.282 0.000
Y85 Sequelae of transport accidents
0.718 0.282 0.000
E03.9 Hypothyroidism, unspecified
0.718 0.282 0.000
E40-E46 Malnutrition
0.718 0.282 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G37 Other demyelinating diseases of central nervous system
0.715 0.285 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.714 0.286 0.000
M92 Other juvenile osteochondrosis
0.714 0.286 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.714 0.286 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.712 0.288 0.000
T93.2 Sequelae of other fractures of lower limb
0.712 0.288 0.000
J17 Pneumonia in diseases classified elsewhere
0.710 0.289 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.710 0.289 0.000
J12 Viral pneumonia, not elsewhere classified
0.710 0.289 0.000
J09 Influenza due to certain identified influenza virus
0.710 0.289 0.000
G40.9 Epilepsy, unspecified
0.710 0.290 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.710 0.290 0.000
G36 Other acute disseminated demyelination
0.710 0.290 0.000
E28 Ovarian dysfunction
0.709 0.291 0.000
J92 Pleural plaque
0.709 0.291 0.000
Z22 Carrier of infectious disease
0.709 0.291 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.708 0.291 0.000
J41 Simple and mucopurulent chronic bronchitis
0.708 0.292 0.000
H11 Other disorders of conjunctiva
0.707 0.293 0.000
E07 Other disorders of thyroid
0.707 0.293 0.000
J45.8 Mixed asthma
0.706 0.294 0.000
J45.1 Nonallergic asthma
0.706 0.294 0.000
H40-H42 Glaucoma
0.706 0.294 0.000
E53.8 Deficiency of other specified B group vitamins
0.705 0.295 0.000
Z50.6 Orthoptic training
0.705 0.295 0.000
Z50.3 Drug rehabilitation
0.705 0.295 0.000
W20-W49 Exposure to inanimate mechanical forces
0.705 0.295 0.000
Z44 Fitting and adjustment of external prosthetic device
0.705 0.295 0.000
T33-T35 Frostbite
0.704 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.704 0.296 0.000
T00-T07 Injuries involving multiple body regions
0.704 0.296 0.000
L10-L14 Bullous disorders
0.703 0.297 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.702 0.298 0.000
S37 Injury of urinary and pelvic organs
0.701 0.299 0.000
T98 Sequelae of other and unspecified effects of external causes
0.700 0.299 0.000
J18.8 Other pneumonia, organism unspecified
0.700 0.300 0.000
J18.2 Hypostatic pneumonia, unspecified
0.700 0.300 0.000
L53 Other erythematous conditions
0.700 0.300 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.700 0.300 0.000
E00 Congenital iodine-deficiency syndrome
0.700 0.300 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.700 0.300 0.000
E26 Hyperaldosteronism
0.699 0.301 0.000
L40-L45 Papulosquamous disorders
0.698 0.302 0.000
M06.4 Inflammatory polyarthropathy
0.697 0.303 0.000
Z63.4 Disappearance and death of family member
0.697 0.303 0.000
J11 Influenza, virus not identified
0.696 0.304 0.000
Z63.8 Other specified problems related to primary support group
0.694 0.306 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.694 0.306 0.000
T92.1 Sequelae of fracture of arm
0.694 0.306 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.694 0.306 0.000
M25.8 Other specified joint disorders
0.694 0.306 0.000
X60-X84 Intentional self-harm
0.693 0.307 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.692 0.308 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.691 0.308 0.000
T93.1 Sequelae of fracture of femur
0.690 0.310 0.000
V80-V89 Other land transport accidents
0.690 0.310 0.000
Z65 Problems related to other psychosocial circumstances
0.690 0.310 0.000
Z64 Problems related to certain psychosocial circumstances
0.690 0.310 0.000
Z62 Other problems related to upbringing
0.690 0.310 0.000
Z61 Problems related to negative life events in childhood
0.690 0.310 0.000
Z58 Problems related to physical environment
0.690 0.310 0.000
Z56 Problems related to employment and unemployment
0.690 0.310 0.000
Z55 Problems related to education and literacy
0.690 0.310 0.000
J94 Other pleural conditions
0.690 0.310 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.690 0.310 0.000
J45.0 Predominantly allergic asthma
0.689 0.311 0.000
M14 Arthropathies in other diseases classified elsewhere
0.687 0.313 0.000
M12 Other specific arthropathies
0.687 0.313 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.687 0.313 0.000
M08 Juvenile arthritis
0.687 0.313 0.000
S43.0 Dislocation of shoulder joint
0.687 0.313 0.000
G93 Other disorders of brain
0.686 0.314 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.685 0.315 0.000
D80-D89 Certain disorders involving the immune mechanism
0.685 0.315 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.684 0.316 0.000
M94.8 Other specified disorders of cartilage
0.683 0.317 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.683 0.317 0.000
S48 Traumatic amputation of shoulder and upper arm
0.683 0.317 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.683 0.317 0.000
S44 Injury of nerves at shoulder and upper arm level
0.683 0.317 0.000
S41 Open wound of shoulder and upper arm
0.683 0.317 0.000
S47 Crushing injury of shoulder and upper arm
0.683 0.317 0.000
E21.3 Hyperparathyroidism, unspecified
0.681 0.319 0.000
Z75 Problems related to medical facilities and other health care
0.681 0.319 0.000
J00-J06 Acute upper respiratory infections
0.681 0.319 0.000
T95 Sequelae of burns, corrosions and frostbite
0.680 0.320 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.680 0.320 0.000
T91 Sequelae of injuries of neck and trunk
0.680 0.320 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.680 0.320 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.680 0.320 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.679 0.321 0.000
M16 Coxarthrosis [arthrosis of hip]
0.678 0.322 0.000
Z29 Need for other prophylactic measures
0.678 0.322 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.678 0.322 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.678 0.322 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.678 0.322 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.678 0.322 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.678 0.322 0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van
0.678 0.322 0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle
0.678 0.322 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.678 0.322 0.000
V10 Pedal cyclist injured in collision with pedestrian or animal
0.678 0.322 0.000
H57 Other disorders of eye and adnexa
0.677 0.323 0.000
Chapter II Neoplasms
0.676 0.324 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.675 0.325 0.000
E34 Other endocrine disorders
0.675 0.325 0.000
E10 Insulin-dependent diabetes mellitus
0.675 0.325 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.675 0.325 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.673 0.327 0.000
M11 Other crystal arthropathies
0.673 0.327 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.672 0.328 0.000
Chapter VIII Diseases of the ear and mastoid process
0.672 0.328 0.000
T90 Sequelae of injuries of head
0.670 0.330 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.670 0.330 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.669 0.331 0.000
L04 Acute lymphadenitis
0.669 0.331 0.000
L01 Impetigo
0.669 0.331 0.000
L00 Staphylococcal scalded skin syndrome
0.669 0.331 0.000
E13 Other specified diabetes mellitus
0.669 0.331 0.000
Z12 Special screening examination for neoplasms
0.669 0.331 0.000
Y59 Other and unspecified vaccines and biological substances
0.666 0.334 0.000
Y58 Bacterial vaccines
0.666 0.334 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.666 0.334 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.666 0.334 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.666 0.334 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.666 0.334 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.666 0.334 0.000
Y48 Anaesthetics and therapeutic gases
0.666 0.334 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.666 0.334 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.666 0.334 0.000
J95-J99 Other diseases of the respiratory system
0.664 0.336 0.000
S12 Fracture of neck
0.663 0.336 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.663 0.337 0.000
M93 Other osteochondropathies
0.663 0.337 0.000
E29 Testicular dysfunction
0.662 0.338 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.661 0.338 0.000
E32 Diseases of thymus
0.661 0.338 0.000
E31 Polyglandular dysfunction
0.661 0.338 0.000
E30 Disorders of puberty, not elsewhere classified
0.661 0.338 0.000
E25 Adrenogenital disorders
0.661 0.338 0.000
E24 Cushing's syndrome
0.661 0.338 0.000
E20 Hypoparathyroidism
0.661 0.338 0.000
J86 Pyothorax
0.660 0.340 0.000
V20-V29 Motorcycle rider injured in transport accident
0.660 0.340 0.000
Z10 Routine general health check-up of defined subpopulation
0.659 0.340 0.000
S32 Fracture of lumbar spine and pelvis
0.659 0.340 0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified
0.659 0.341 0.000
Z41.8 Other procedures for purposes other than remedying health state
0.659 0.341 0.000
Z41.3 Ear piercing
0.659 0.341 0.000
Z41.2 Routine and ritual circumcision
0.659 0.341 0.000
Z41.0 Hair transplant
0.659 0.341 0.000
G70 Myasthenia gravis and other myoneural disorders
0.658 0.342 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.657 0.343 0.000
M25.46 Effusion of joint (Lower leg)
0.657 0.343 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.657 0.343 0.000
E05.8 Other thyrotoxicosis
0.657 0.343 0.000
E05.5 Thyroid crisis or storm
0.657 0.343 0.000
E05.4 Thyrotoxicosis factitia
0.657 0.343 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.657 0.343 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.657 0.343 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.657 0.343 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.657 0.343 0.000
Z43 Attention to artificial openings
0.656 0.344 0.000
Z76 Persons encountering health services in other circumstances
0.655 0.345 0.000
L82 Seborrhoeic keratosis
0.655 0.345 0.000
M19 Other arthrosis
0.654 0.346 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.653 0.347 0.000
M82 Osteoporosis in diseases classified elsewhere
0.653 0.347 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.653 0.347 0.000
Z60.9 Problem related to social environment, unspecified
0.652 0.348 0.000
Z60.8 Other problems related to social environment
0.652 0.348 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.652 0.348 0.000
Z60.4 Social exclusion and rejection
0.652 0.348 0.000
Z60.3 Acculturation difficulty
0.652 0.348 0.000
Z60.1 Atypical parenting situation
0.652 0.348 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.652 0.348 0.000
Y89 Sequelae of other external causes
0.651 0.348 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.651 0.348 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.651 0.349 0.000
V18.4 Driver injured in traffic accident
0.651 0.349 0.000
V18.5 Passenger injured in traffic accident
0.651 0.349 0.000
V18.3 Person injured while boarding or alighting
0.651 0.349 0.000
V18.1 Passenger injured in nontraffic accident
0.651 0.349 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.651 0.349 0.000
L51 Erythema multiforme
0.650 0.349 0.000
Y42.7 Androgens and anabolic congeners
0.650 0.350 0.000
M21.0 Valgus deformity, not elsewhere classified
0.650 0.350 0.000
E61 Deficiency of other nutrient elements
0.649 0.351 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.649 0.351 0.000
M25.0 Haemarthrosis
0.649 0.351 0.000
L60-L75 Disorders of skin appendages
0.649 0.351 0.000
Z48.0 Attention to surgical dressings and sutures
0.648 0.352 0.000
Z28 Immunisation not carried out
0.647 0.353 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.647 0.353 0.000
Z26 Need for immunisation against other single infectious diseases
0.647 0.353 0.000
Z25 Need for immunisation against other single viral diseases
0.647 0.353 0.000
Z24 Need for immunisation against certain single viral diseases
0.647 0.353 0.000
Z23 Need for immunisation against single bacterial diseases
0.647 0.353 0.000
Z20 Contact with and exposure to communicable diseases
0.647 0.353 0.000
S90 Superficial injury of ankle and foot
0.647 0.353 0.000
Chapter I Certain infectious and parasitic diseases
0.646 0.354 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.645 0.355 0.000
D68 Other coagulation defects
0.644 0.356 0.000
D61 Other aplastic anaemias
0.643 0.357 0.000
E04.9 Non-toxic goitre, unspecified
0.643 0.357 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.642 0.358 0.000
Z52 Donors of organs and tissues
0.642 0.358 0.000
M21.6 Other acquired deformities of ankle and foot
0.642 0.358 0.000
G81 Hemiplegia
0.641 0.359 0.000
M35.3 Polymyalgia rheumatica
0.641 0.359 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.641 0.359 0.000
M33 Dermatopolymyositis
0.641 0.359 0.000
M32 Systemic lupus erythematosus
0.641 0.359 0.000
M30 Polyarteritis nodosa and related conditions
0.641 0.359 0.000
D55-D59 Haemolytic anaemias
0.641 0.359 0.000
M15 Polyarthrosis
0.641 0.359 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.640 0.360 0.000
S36 Injury of intra-abdominal organs
0.640 0.360 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.640 0.360 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.640 0.360 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.640 0.360 0.000
S31 Open wound of abdomen, lower back and pelvis
0.640 0.360 0.000
S80-S89 Injuries to the knee and lower leg
0.640 0.360 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.639 0.361 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.639 0.361 0.000
M31 Other necrotising vasculopathies
0.639 0.361 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.639 0.361 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.639 0.361 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.638 0.362 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.637 0.363 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.636 0.364 0.000
Y57.8 Other drugs and medicaments
0.636 0.364 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.636 0.364 0.000
S49.8 Other specified injuries of shoulder and upper arm
0.636 0.364 0.000
S49.7 Multiple injuries of shoulder and upper arm
0.636 0.364 0.000
G71 Primary disorders of muscles
0.635 0.365 0.000
W07.9 Unspecified place
0.635 0.365 0.000
G90 Disorders of autonomic nervous system
0.635 0.365 0.000
Z59.8 Other problems relating to housing and economic circumstances
0.634 0.366 0.000
Z01.3 Examination of blood pressure
0.633 0.367 0.000
Z01.2 Dental examination
0.633 0.367 0.000
Z01.1 Examination of ears and hearing
0.633 0.367 0.000
Z01.0 Examination of eyes and vision
0.633 0.367 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.633 0.367 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.633 0.367 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.633 0.367 0.000
T93.0 Sequelae of open wound of lower limb
0.633 0.367 0.000
M06.8 Other specified rheumatoid arthritis
0.633 0.367 0.000
M06.3 Rheumatoid nodule
0.633 0.367 0.000
M06.2 Rheumatoid bursitis
0.633 0.367 0.000
M06.1 Adult-onset Still's disease
0.633 0.367 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.633 0.367 0.000
T14 Injury of unspecified body region
0.632 0.367 0.000
Z63.7 Other stressful life events affecting family and household
0.632 0.368 0.000
M84 Disorders of continuity of bone
0.632 0.368 0.000
C51-C58 Malignant neoplasms of female genital organs
0.632 0.368 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.632 0.368 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.630 0.370 0.000
G20 Parkinson's disease
0.630 0.370 0.000
E23 Hypofunction and other disorders of pituitary gland
0.630 0.370 0.000
M13.8 Other specified arthritis
0.629 0.370 0.000
M13.1 Monoarthritis, not elsewhere classified
0.629 0.370 0.000
J47 Bronchiectasis
0.630 0.370 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.629 0.371 0.000
H54.6 Unqualified visual loss, one eye
0.629 0.371 0.000
H54.5 Low vision, one eye
0.629 0.371 0.000
H54.3 Unqualified visual loss, both eyes
0.629 0.371 0.000
H54.2 Low vision, both eyes
0.629 0.371 0.000
H54.1 Blindness, one eye, low vision, other eye
0.629 0.371 0.000
M70-M79 Other soft tissue disorders
0.629 0.371 0.000
W07.0 Home
0.629 0.371 0.000
Y52 Agents primarily affecting the cardiovascular system
0.628 0.372 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.627 0.373 0.000
Z49.2 Other dialysis
0.627 0.373 0.000
Z49.1 Extracorporeal dialysis
0.626 0.374 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.626 0.374 0.000
S92 Fracture of foot, except ankle
0.625 0.375 0.000
J93.8 Other pneumothorax
0.625 0.375 0.000
Y95 Nosocomial condition
0.623 0.377 0.000
M85 Other disorders of bone density and structure
0.623 0.377 0.000
S42 Fracture of shoulder and upper arm
0.623 0.377 0.000
M87 Osteonecrosis
0.623 0.377 0.000
E22 Hyperfunction of pituitary gland
0.623 0.377 0.000
E65-E68 Obesity and other hyperalimentation
0.623 0.377 0.000
M83 Adult osteomalacia
0.622 0.378 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.622 0.378 0.000
J15.9 Bacterial pneumonia, unspecified
0.622 0.378 0.000
J15.8 Other bacterial pneumonia
0.622 0.378 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.622 0.378 0.000
J15.5 Pneumonia due to Escherichia coli
0.622 0.378 0.000
J15.4 Pneumonia due to other streptococci
0.622 0.378 0.000
J15.3 Pneumonia due to streptococcus, group B
0.622 0.378 0.000
J18.9 Pneumonia, unspecified
0.621 0.379 0.000
J15.1 Pneumonia due to Pseudomonas
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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