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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12333245
log Bayes Factor = 16.0821
Chromosome 6   position 32,019,769  (GRCh37) Explore rs12333245 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.002 0.998
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
E65-E68 Obesity and other hyperalimentation
0.000 0.009 0.991
E11.3 With ophthalmic complications
0.000 0.009 0.991
E10.3 With ophthalmic complications
0.000 0.011 0.989
E66 Obesity
0.000 0.014 0.986
E10.1 With ketoacidosis
0.000 0.018 0.982
E66.8 Other obesity
0.000 0.028 0.972
E14 Unspecified diabetes mellitus
0.000 0.037 0.963
E66.9 Obesity, unspecified
0.000 0.071 0.929
E14.9 Without complications
0.000 0.073 0.927
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.079 0.921
M06 Other rheumatoid arthritis
0.000 0.092 0.908
E10.5 With peripheral circulatory complications
0.000 0.113 0.887
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.120 0.880
E11.5 With peripheral circulatory complications
0.000 0.133 0.867
E11.9 Without complications
0.000 0.139 0.861
E11.4 With neurological complications
0.000 0.148 0.852
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.152 0.848
E10.4 With neurological complications
0.000 0.165 0.835
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.168 0.832
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.171 0.829
E10.2 With renal complications
0.000 0.187 0.813
E05.9 Thyrotoxicosis, unspecified
0.000 0.208 0.792
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.214 0.786
E06 Thyroiditis
0.000 0.215 0.785
E11.2 With renal complications
0.000 0.215 0.785
M05-M14 Inflammatory polyarthropathies
0.000 0.217 0.783
M06.0 Seronegative rheumatoid arthritis
0.000 0.228 0.772
M05 Seropositive rheumatoid arthritis
0.000 0.239 0.761
E14.3 With ophthalmic complications
0.000 0.241 0.759
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.247 0.753
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.254 0.746
M06.3 Rheumatoid nodule
0.000 0.263 0.737
E11.1 With ketoacidosis
0.000 0.264 0.736
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.274 0.726
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.284 0.716
E67 Other hyperalimentation
0.000 0.289 0.711
E68 Sequelae of hyperalimentation
0.000 0.289 0.711
E66.1 Drug-induced obesity
0.000 0.293 0.707
E66.0 Obesity due to excess calories
0.000 0.293 0.707
E65 Localised adiposity
0.000 0.299 0.701
E50-E64 Other nutritional deficiencies
0.000 0.303 0.697
E14.8 With unspecified complications
0.000 0.310 0.690
E14.7 With multiple complications
0.000 0.310 0.690
E14.6 With other specified complications
0.000 0.310 0.690
E14.5 With peripheral circulatory complications
0.000 0.310 0.690
E14.4 With neurological complications
0.000 0.310 0.690
E14.2 Withrenal complications
0.000 0.310 0.690
E14.1 With ketoacidosis
0.000 0.310 0.690
E14.0 With coma
0.000 0.310 0.690
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.315 0.685
E11.8 With unspecified complications
0.000 0.324 0.676
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.330 0.670
E05.8 Other thyrotoxicosis
0.000 0.339 0.660
E05.5 Thyroid crisis or storm
0.000 0.339 0.660
E05.4 Thyrotoxicosis factitia
0.000 0.339 0.660
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.339 0.660
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.339 0.660
E40-E46 Malnutrition
0.000 0.345 0.655
M06.8 Other specified rheumatoid arthritis
0.000 0.349 0.651
M06.2 Rheumatoid bursitis
0.000 0.349 0.651
M06.1 Adult-onset Still's disease
0.000 0.349 0.651
E11.6 With other specified complications
0.000 0.349 0.651
E06.3 Autoimmune thyroiditis
0.000 0.363 0.637
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.365 0.635
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.366 0.634
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.385 0.615
M06.34 Rheumatoid nodule (Hand)
0.000 0.386 0.614
M14 Arthropathies in other diseases classified elsewhere
0.000 0.397 0.603
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.399 0.601
M13 Other arthritis
0.000 0.399 0.601
E07 Other disorders of thyroid
0.000 0.400 0.600
M10 Gout
0.000 0.400 0.600
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.419 0.580
E61 Deficiency of other nutrient elements
0.000 0.431 0.569
E13 Other specified diabetes mellitus
0.000 0.432 0.568
E11.0 With coma
0.000 0.436 0.564
E06.5 Other chronic thyroiditis
0.000 0.437 0.563
E06.4 Drug-induced thyroiditis
0.000 0.437 0.563
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.437 0.563
E06.1 Subacute thyroiditis
0.000 0.437 0.563
E06.0 Acute thyroiditis
0.000 0.437 0.563
M12 Other specific arthropathies
0.000 0.439 0.561
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.439 0.561
M08 Juvenile arthritis
0.000 0.439 0.561
E03.8 Other specified hypothyroidism
0.000 0.444 0.556
E06.9 Thyroiditis, unspecified
0.000 0.445 0.555
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.447 0.553
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.447 0.553
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.447 0.553
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.447 0.553
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.447 0.553
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.447 0.553
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.447 0.553
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.447 0.553
M05.8 Other seropositive rheumatoid arthritis
0.000 0.454 0.546
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.454 0.546
M05.2 Rheumatoid vasculitis
0.000 0.454 0.546
M05.1 Rheumatoid lung disease
0.000 0.454 0.546
M05.0 Felty's syndrome
0.000 0.454 0.546
E20-E35 Disorders of other endocrine glands
0.000 0.456 0.544
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.465 0.535
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.465 0.535
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.465 0.535
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.465 0.535
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.465 0.535
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.465 0.535
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.465 0.535
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.465 0.535
M06.4 Inflammatory polyarthropathy
0.000 0.470 0.529
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.471 0.528
M06.38 Rheumatoid nodule (Other)
0.000 0.471 0.528
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.471 0.528
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.471 0.528
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.471 0.528
M06.33 Rheumatoid nodule (Forearm)
0.000 0.471 0.528
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.471 0.528
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.471 0.528
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.471 0.528
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E67.8 Other specified hyperalimentation
0.000 0.490 0.510
E67.3 Hypervitaminosis D
0.000 0.490 0.510
E67.2 Megavitamin-B6 syndrome
0.000 0.490 0.510
E67.1 Hypercarotenaemia
0.000 0.490 0.510
E67.0 Hypervitaminosis A
0.000 0.490 0.510
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.500 0.500
E63 Other nutritional deficiencies
0.000 0.500 0.500
E56 Other vitamin deficiencies
0.000 0.500 0.500
E51 Thiamine deficiency
0.000 0.500 0.500
E50 Vitamin A deficiency
0.000 0.500 0.500
E60 Dietary zinc deficiency
0.000 0.500 0.500
E59 Dietary selenium deficiency
0.000 0.500 0.500
E58 Dietary calcium deficiency
0.000 0.500 0.500
E54 Ascorbic acid deficiency
0.000 0.500 0.500
E52 Niacin deficiency [pellagra]
0.000 0.500 0.500
M13.0 Polyarthritis, unspecified
0.000 0.504 0.496
E15 Nondiabetic hypoglycaemic coma
0.000 0.519 0.481
E61.1 Iron deficiency
0.000 0.522 0.478
E53 Deficiency of other B group vitamins
0.000 0.524 0.475
M14.6 Neuropathic arthropathy
0.000 0.526 0.474
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.530 0.469
E45 Retarded development following protein-energy malnutrition
0.000 0.530 0.469
E43 Unspecified severe protein-energy malnutrition
0.000 0.530 0.469
E42 Marasmic kwashiorkor
0.000 0.530 0.469
E41 Nutritional marasmus
0.000 0.530 0.469
E40 Kwashiorkor
0.000 0.530 0.469
M10.9 Gout, unspecified
0.000 0.531 0.469
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.533 0.467
M06.18 Adult-onset Still's disease (Other)
0.000 0.533 0.467
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.533 0.467
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.533 0.467
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.533 0.467
M06.14 Adult-onset Still's disease (Hand)
0.000 0.533 0.467
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.533 0.467
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.533 0.467
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.533 0.467
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.533 0.467
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.533 0.467
M06.28 Rheumatoid bursitis (Other)
0.000 0.533 0.467
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.533 0.467
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.533 0.467
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.533 0.467
M06.24 Rheumatoid bursitis (Hand)
0.000 0.533 0.467
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.533 0.467
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.533 0.467
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.533 0.467
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.533 0.467
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.533 0.467
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.533 0.467
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.533 0.467
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.533 0.467
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.533 0.467
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.533 0.467
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.533 0.467
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.533 0.467
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.533 0.467
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.533 0.467
M11 Other crystal arthropathies
0.001 0.535 0.464
M07 Psoriatic and enteropathic arthropathies
0.000 0.545 0.454
E27 Other disorders of adrenal gland
0.000 0.554 0.446
E16 Other disorders of pancreatic internal secretion
0.000 0.566 0.434
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.568 0.432
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.568 0.432
M14.4 Arthropathy in amyloidosis
0.000 0.568 0.432
M14.3 Lipoid dermatoarthritis
0.000 0.568 0.432
M14.2 Diabetic arthropathy
0.000 0.568 0.432
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.568 0.432
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.568 0.432
M13.8 Other specified arthritis
0.000 0.569 0.431
M13.1 Monoarthritis, not elsewhere classified
0.000 0.569 0.431
E07.1 Dyshormogenetic goitre
0.000 0.569 0.430
E07.0 Hypersecretion of calcitonin
0.000 0.569 0.430
M10.4 Other secondary gout
0.000 0.570 0.430
M10.3 Gout due to impairment of renal function
0.000 0.570 0.430
M10.2 Drug-induced gout
0.000 0.570 0.430
M10.1 Lead-induced gout
0.000 0.570 0.430
M10.0 Idiopathic gout
0.000 0.570 0.430
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.573 0.427
M13.00 Polyarthritis, unspecified (Multiple sites)
0.000 0.574 0.426
E07.8 Other specified disorders of thyroid
0.000 0.580 0.420
E27.1 Primary adrenocortical insufficiency
0.000 0.587 0.413
E61.9 Deficiency of nutrient element, unspecified
0.000 0.592 0.408
E61.8 Deficiency of other specified nutrient elements
0.000 0.592 0.408
E61.7 Deficiency of multiple nutrient elements
0.000 0.592 0.408
E61.6 Vanadium deficiency
0.000 0.592 0.408
E61.5 Molybdenum deficiency
0.000 0.592 0.408
E61.4 Chromium deficiency
0.000 0.592 0.408
E61.3 Manganese deficiency
0.000 0.592 0.408
E61.2 Magnesium deficiency
0.000 0.592 0.408
E61.0 Copper deficiency
0.000 0.592 0.408
E46 Unspecified protein-energy malnutrition
0.000 0.592 0.407
E13.8 With unspecified complications
0.000 0.593 0.407
E13.7 With multiple complications
0.000 0.593 0.407
E13.6 With other specified complications
0.000 0.593 0.407
E13.5 With peripheral circulatory complications
0.000 0.593 0.407
E13.4 With neurological complications
0.000 0.593 0.407
E13.3 With ophthalmic complications
0.000 0.593 0.407
E13.2 With renal complications
0.000 0.593 0.407
E13.1 With ketoacidosis
0.000 0.593 0.407
E13.0 With coma
0.000 0.593 0.407
M08.9 Juvenile arthritis, unspecified
0.000 0.597 0.402
M08.8 Other juvenile arthritis
0.000 0.597 0.402
M08.4 Pauciarticular juvenile arthritis
0.000 0.597 0.402
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.597 0.402
M08.2 Juvenile arthritis with systemic onset
0.000 0.597 0.402
M08.1 Juvenile ankylosing spondylitis
0.000 0.597 0.402
M08.0 Juvenile rheumatoid arthritis
0.000 0.597 0.402
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.597 0.402
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.597 0.402
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.597 0.402
M09.0 Juvenile arthritis in psoriasis
0.000 0.597 0.402
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.597 0.402
M12.5 Traumatic arthropathy
0.000 0.597 0.402
M12.4 Intermittent hydrarthrosis
0.000 0.597 0.402
M12.3 Palindromic rheumatism
0.000 0.597 0.402
M12.2 Villonodular synovitis (pigmented)
0.000 0.597 0.402
M12.1 Kaschin-Beck disease
0.000 0.597 0.402
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.597 0.402
E55 Vitamin D deficiency
0.000 0.602 0.398
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.606 0.394
E23 Hypofunction and other disorders of pituitary gland
0.000 0.607 0.393
M13.9 Arthritis, unspecified
0.000 0.608 0.392
M05.09 Felty's syndrome (Site unspecified)
0.000 0.608 0.391
M05.08 Felty's syndrome (Other)
0.000 0.608 0.391
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.608 0.391
M05.06 Felty's syndrome (Lower leg)
0.000 0.608 0.391
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.608 0.391
M05.04 Felty's syndrome (Hand)
0.000 0.608 0.391
M05.03 Felty's syndrome (Forearm)
0.000 0.608 0.391
M05.02 Felty's syndrome (Upper arm)
0.000 0.608 0.391
M05.01 Felty's syndrome (Shoulder region)
0.000 0.608 0.391
M05.00 Felty's syndrome (Multiple sites)
0.000 0.608 0.391
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.608 0.391
M05.18 Rheumatoid lung disease (Other)
0.000 0.608 0.391
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.608 0.391
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.608 0.391
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.608 0.391
M05.14 Rheumatoid lung disease (Hand)
0.000 0.608 0.391
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.608 0.391
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.608 0.391
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.608 0.391
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.608 0.391
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.608 0.391
M05.28 Rheumatoid vasculitis (Other)
0.000 0.608 0.391
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.608 0.391
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.608 0.391
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.608 0.391
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.608 0.391
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.608 0.391
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.608 0.391
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.608 0.391
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.608 0.391
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.608 0.391
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.608 0.391
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.608 0.391
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.608 0.391
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.608 0.391
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.608 0.391
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.608 0.391
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.608 0.391
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.608 0.391
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.608 0.391
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.608 0.391
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.608 0.391
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.608 0.391
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.608 0.391
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.608 0.391
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.608 0.391
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.608 0.391
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.608 0.391
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.608 0.391
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.608 0.391
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.610 0.390
E32 Diseases of thymus
0.000 0.610 0.390
E31 Polyglandular dysfunction
0.000 0.610 0.390
E30 Disorders of puberty, not elsewhere classified
0.000 0.610 0.390
E25 Adrenogenital disorders
0.000 0.610 0.390
E20 Hypoparathyroidism
0.000 0.610 0.390
E28 Ovarian dysfunction
0.000 0.615 0.385
E34 Other endocrine disorders
0.000 0.618 0.382
E29 Testicular dysfunction
0.000 0.618 0.382
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.620 0.379
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.620 0.379
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.620 0.379
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.620 0.379
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.620 0.379
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.620 0.379
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.620 0.379
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.620 0.379
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.001 0.630 0.369
M13.94 Arthritis, unspecified (Hand)
0.000 0.633 0.367
E53.8 Deficiency of other specified B group vitamins
0.000 0.634 0.366
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.638 0.362
E50.9 Vitamin A deficiency, unspecified
0.000 0.642 0.358
E50.8 Other manifestations of vitamin A deficiency
0.000 0.642 0.358
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.642 0.358
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.642 0.358
E50.5 Vitamin A deficiency with night blindness
0.000 0.642 0.358
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.642 0.358
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.642 0.358
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.642 0.358
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.642 0.358
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.642 0.358
E51.9 Thiamine deficiency, unspecified
0.000 0.642 0.358
E51.8 Other manifestations of thiamine deficiency
0.000 0.642 0.358
E51.2 Wernicke's encephalopathy
0.000 0.642 0.358
E51.1 Beriberi
0.000 0.642 0.358
E56.9 Vitamin deficiency, unspecified
0.000 0.642 0.358
E56.8 Deficiency of other vitamins
0.000 0.642 0.358
E56.1 Deficiency of vitamin K
0.000 0.642 0.358
E56.0 Deficiency of vitamin E
0.000 0.642 0.358
E63.9 Nutritional deficiency, unspecified
0.000 0.642 0.358
E63.8 Other specified nutritional deficiencies
0.000 0.642 0.358
E63.1 Imbalance of constituents of food intake
0.000 0.642 0.358
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.642 0.358
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.642 0.358
E64.8 Sequelae of other nutritional deficiencies
0.000 0.642 0.358
E64.3 Sequelae of rickets
0.000 0.642 0.358
E64.2 Sequelae of vitamin C deficiency
0.000 0.642 0.358
E64.1 Sequelae of vitamin A deficiency
0.000 0.642 0.358
E64.0 Sequelae of protein-energy malnutrition
0.000 0.642 0.358
M13.08 Polyarthritis, unspecified (Other)
0.000 0.644 0.355
M13.07 Polyarthritis, unspecified (Ankle and foot)
0.000 0.644 0.355
M13.06 Polyarthritis, unspecified (Lower leg)
0.000 0.644 0.355
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)
0.000 0.644 0.355
M13.04 Polyarthritis, unspecified (Hand)
0.000 0.644 0.355
M13.03 Polyarthritis, unspecified (Forearm)
0.000 0.644 0.355
M13.02 Polyarthritis, unspecified (Upper arm)
0.000 0.644 0.355
M13.01 Polyarthritis, unspecified (Shoulder region)
0.000 0.644 0.355
M10.96 Gout, unspecified (Lower leg)
0.000 0.646 0.354
E26 Hyperaldosteronism
0.000 0.649 0.351
I63.9 Cerebral infarction, unspecified
0.000 0.656 0.344
M13.09 Polyarthritis, unspecified (Site unspecified)
0.000 0.657 0.343
E53.1 Pyridoxine deficiency
0.000 0.659 0.341
E53.0 Riboflavin deficiency
0.000 0.659 0.341
E44.1 Mild protein-energy malnutrition
0.000 0.663 0.337
E44.0 Moderate protein-energy malnutrition
0.000 0.663 0.337
M10.98 Gout, unspecified (Other)
0.000 0.663 0.336
M10.95 Gout, unspecified (Pelvic region and thigh)
0.000 0.663 0.336
M10.93 Gout, unspecified (Forearm)
0.000 0.663 0.336
M10.92 Gout, unspecified (Upper arm)
0.000 0.663 0.336
M10.91 Gout, unspecified (Shoulder region)
0.000 0.663 0.336
M10.90 Gout, unspecified (Multiple sites)
0.000 0.663 0.336
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.664 0.336
E24 Cushing's syndrome
0.000 0.666 0.334
M11.9 Crystal arthropathy, unspecified
0.001 0.667 0.333
M11.8 Other specified crystal arthropathies
0.001 0.667 0.333
M11.1 Familial chondrocalcinosis
0.001 0.667 0.333
M11.0 Hydroxyapatite deposition disease
0.001 0.667 0.333
M10.94 Gout, unspecified (Hand)
0.000 0.667 0.333
E07.9 Disorder of thyroid, unspecified
0.000 0.668 0.331
E27.8 Other specified disorders of adrenal gland
0.000 0.669 0.331
M07.6 Other enteropathic arthropathies
0.000 0.674 0.326
M07.5 Arthropathy in ulcerative colitis
0.000 0.674 0.326
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.674 0.326
M07.2 Psoriatic spondylitis
0.000 0.674 0.326
M07.1 Arthritis mutilans
0.000 0.674 0.326
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.674 0.326
E27.5 Adrenomedullary hyperfunction
0.000 0.680 0.320
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.680 0.320
E27.2 Addisonian crisis
0.000 0.680 0.320
E27.0 Other adrenocortical overactivity
0.000 0.680 0.320
E22 Hyperfunction of pituitary gland
0.000 0.681 0.319
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.000 0.681 0.319
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.689 0.311
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.689 0.311
E16.4 Abnormal secretion of gastrin
0.000 0.689 0.311
E16.3 Increased secretion of glucagon
0.000 0.689 0.311
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.689 0.311
E23.2 Diabetes insipidus
0.000 0.690 0.310
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)
0.000 0.691 0.309
M13.18 Monoarthritis, not elsewhere classified (Other)
0.000 0.691 0.309
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)
0.000 0.691 0.309
M13.16 Monoarthritis, not elsewhere classified (Lower leg)
0.000 0.691 0.309
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)
0.000 0.691 0.309
M13.14 Monoarthritis, not elsewhere classified (Hand)
0.000 0.691 0.309
M13.13 Monoarthritis, not elsewhere classified (Forearm)
0.000 0.691 0.309
M13.12 Monoarthritis, not elsewhere classified (Upper arm)
0.000 0.691 0.309
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)
0.000 0.691 0.309
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)
0.000 0.691 0.309
M13.89 Other specified arthritis (Site unspecified)
0.000 0.691 0.309
M13.88 Other specified arthritis (Other)
0.000 0.691 0.309
M13.87 Other specified arthritis (Ankle and foot)
0.000 0.691 0.309
M13.86 Other specified arthritis (Lower leg)
0.000 0.691 0.309
M13.85 Other specified arthritis (Pelvic region and thigh)
0.000 0.691 0.309
M13.84 Other specified arthritis (Hand)
0.000 0.691 0.309
M13.83 Other specified arthritis (Forearm)
0.000 0.691 0.309
M13.82 Other specified arthritis (Upper arm)
0.000 0.691 0.309
M13.81 Other specified arthritis (Shoulder region)
0.000 0.691 0.309
M13.80 Other specified arthritis (Multiple sites)
0.000 0.691 0.309
M10.09 Idiopathic gout (Site unspecified)
0.000 0.691 0.309
M10.08 Idiopathic gout (Other)
0.000 0.691 0.309
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.691 0.309
M10.06 Idiopathic gout (Lower leg)
0.000 0.691 0.309
M10.05 Idiopathic gout (Pelvic region and thigh)
0.000 0.691 0.309
M10.04 Idiopathic gout (Hand)
0.000 0.691 0.309
M10.03 Idiopathic gout (Forearm)
0.000 0.691 0.309
M10.02 Idiopathic gout (Upper arm)
0.000 0.691 0.309
M10.01 Idiopathic gout (Shoulder region)
0.000 0.691 0.309
M10.00 Idiopathic gout (Multiple sites)
0.000 0.691 0.309
M10.19 Lead-induced gout (Site unspecified)
0.000 0.691 0.309
M10.18 Lead-induced gout (Other)
0.000 0.691 0.309
M10.17 Lead-induced gout (Ankle and foot)
0.000 0.691 0.309
M10.16 Lead-induced gout (Lower leg)
0.000 0.691 0.309
M10.15 Lead-induced gout (Pelvic region and thigh)
0.000 0.691 0.309
M10.14 Lead-induced gout (Hand)
0.000 0.691 0.309
M10.13 Lead-induced gout (Forearm)
0.000 0.691 0.309
M10.12 Lead-induced gout (Upper arm)
0.000 0.691 0.309
M10.11 Lead-induced gout (Shoulder region)
0.000 0.691 0.309
M10.10 Lead-induced gout (Multiple sites)
0.000 0.691 0.309
M10.29 Drug-induced gout (Site unspecified)
0.000 0.691 0.309
M10.28 Drug-induced gout (Other)
0.000 0.691 0.309
M10.27 Drug-induced gout (Ankle and foot)
0.000 0.691 0.309
M10.26 Drug-induced gout (Lower leg)
0.000 0.691 0.309
M10.25 Drug-induced gout (Pelvic region and thigh)
0.000 0.691 0.309
M10.24 Drug-induced gout (Hand)
0.000 0.691 0.309
M10.23 Drug-induced gout (Forearm)
0.000 0.691 0.309
M10.22 Drug-induced gout (Upper arm)
0.000 0.691 0.309
M10.21 Drug-induced gout (Shoulder region)
0.000 0.691 0.309
M10.20 Drug-induced gout (Multiple sites)
0.000 0.691 0.309
M10.39 Gout due to impairment of renal function (Site unspecified)
0.000 0.691 0.309
M10.38 Gout due to impairment of renal function (Other)
0.000 0.691 0.309
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.000 0.691 0.309
M10.36 Gout due to impairment of renal function (Lower leg)
0.000 0.691 0.309
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.000 0.691 0.309
M10.34 Gout due to impairment of renal function (Hand)
0.000 0.691 0.309
M10.33 Gout due to impairment of renal function (Forearm)
0.000 0.691 0.309
M10.32 Gout due to impairment of renal function (Upper arm)
0.000 0.691 0.309
M10.31 Gout due to impairment of renal function (Shoulder region)
0.000 0.691 0.309
M10.30 Gout due to impairment of renal function (Multiple sites)
0.000 0.691 0.309
M10.49 Other secondary gout (Site unspecified)
0.000 0.691 0.309
M10.48 Other secondary gout (Other)
0.000 0.691 0.309
M10.47 Other secondary gout (Ankle and foot)
0.000 0.691 0.309
M10.46 Other secondary gout (Lower leg)
0.000 0.691 0.309
M10.45 Other secondary gout (Pelvic region and thigh)
0.000 0.691 0.309
M10.44 Other secondary gout (Hand)
0.000 0.691 0.309
M10.43 Other secondary gout (Forearm)
0.000 0.691 0.309
M10.42 Other secondary gout (Upper arm)
0.000 0.691 0.309

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

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