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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1233602
log Bayes Factor = 50.1029
Chromosome 6   position 28,733,403  (GRCh37) Explore rs1233602 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.020 0.980
E10 Insulin-dependent diabetes mellitus
0.000 0.024 0.976
E10.9 Without complications
0.000 0.026 0.974
E10.3 With ophthalmic complications
0.000 0.033 0.967
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.042 0.958
E10-E14 Diabetes mellitus
0.000 0.068 0.932
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.080 0.920
E00-E07 Disorders of thyroid gland
0.000 0.082 0.918
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.085 0.915
E16 Other disorders of pancreatic internal secretion
0.000 0.087 0.913
E16.2 Hypoglycaemia, unspecified
0.000 0.090 0.910
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.102 0.898
E10.1 With ketoacidosis
0.000 0.106 0.894
E10.2 With renal complications
0.000 0.128 0.872
E10.4 With neurological complications
0.000 0.198 0.802
E05.8 Other thyrotoxicosis
0.000 0.207 0.793
E40-E46 Malnutrition
0.000 0.251 0.749
E13 Other specified diabetes mellitus
0.000 0.255 0.744
E10.0 With coma
0.000 0.285 0.715
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.291 0.709
E16.1 Other hypoglycaemia
0.000 0.299 0.701
E10.7 With multiple complications
0.000 0.301 0.698
E05.5 Thyroid crisis or storm
0.000 0.313 0.687
E05.4 Thyrotoxicosis factitia
0.000 0.313 0.687
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.313 0.687
E12 Malnutrition-related diabetes mellitus
0.000 0.331 0.669
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.342 0.658
E00 Congenital iodine-deficiency syndrome
0.000 0.342 0.658
E15 Nondiabetic hypoglycaemic coma
0.000 0.344 0.656
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.345 0.654
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.345 0.654
E16.4 Abnormal secretion of gastrin
0.000 0.345 0.654
E16.3 Increased secretion of glucagon
0.000 0.345 0.654
E10.6 With other specified complications
0.000 0.363 0.636
E46 Unspecified protein-energy malnutrition
0.000 0.374 0.626
E13.9 Without complications
0.000 0.390 0.610
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.392 0.607
E14 Unspecified diabetes mellitus
0.000 0.421 0.579
E06 Thyroiditis
0.000 0.425 0.575
E07 Other disorders of thyroid
0.000 0.442 0.558
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.463 0.537
E45 Retarded development following protein-energy malnutrition
0.000 0.463 0.537
E43 Unspecified severe protein-energy malnutrition
0.000 0.463 0.537
E42 Marasmic kwashiorkor
0.000 0.463 0.537
E41 Nutritional marasmus
0.000 0.463 0.537
E40 Kwashiorkor
0.000 0.463 0.537
E13.8 With unspecified complications
0.000 0.466 0.534
E13.7 With multiple complications
0.000 0.466 0.534
E13.6 With other specified complications
0.000 0.466 0.534
E13.5 With peripheral circulatory complications
0.000 0.466 0.534
E13.4 With neurological complications
0.000 0.466 0.534
E13.2 With renal complications
0.000 0.466 0.534
E13.1 With ketoacidosis
0.000 0.466 0.534
E13.0 With coma
0.000 0.466 0.534
E13.3 With ophthalmic complications
0.000 0.466 0.534
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.476 0.524
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.479 0.521
E10.8 With unspecified complications
0.000 0.492 0.508
E10.5 With peripheral circulatory complications
0.000 0.495 0.505
C20 Malignant neoplasm of rectum
0.000 0.519 0.481
C15-C26 Malignant neoplasms of digestive organs
0.000 0.520 0.480
E12.9 Without complications
0.000 0.520 0.479
E12.8 With unspecified complications
0.000 0.520 0.479
E12.7 With multiple complications
0.000 0.520 0.479
E12.6 With other specified complications
0.000 0.520 0.479
E12.5 With peripheral circulatory complications
0.000 0.520 0.479
E12.4 With neurological complications
0.000 0.520 0.479
E12.3 With ophthalmic complications
0.000 0.520 0.479
E12.2 With renal complications
0.000 0.520 0.479
E12.1 With ketoacidosis
0.000 0.520 0.479
E12.0 With coma
0.000 0.520 0.479
E06.9 Thyroiditis, unspecified
0.000 0.521 0.479
E14.1 With ketoacidosis
0.000 0.524 0.476
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.528 0.472
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.528 0.472
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.528 0.472
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.528 0.472
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.528 0.472
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.528 0.472
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.528 0.472
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.528 0.472
C15 Malignant neoplasm of oesophagus
0.000 0.540 0.460
E14.3 With ophthalmic complications
0.000 0.543 0.457
E07.8 Other specified disorders of thyroid
0.000 0.556 0.444
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.444 0.556 0.000
E14.6 With other specified complications
0.000 0.565 0.435
E14.4 With neurological complications
0.000 0.576 0.424
E14.7 With multiple complications
0.000 0.585 0.415
E14.8 With unspecified complications
0.000 0.585 0.414
E06.1 Subacute thyroiditis
0.000 0.587 0.413
E06.4 Drug-induced thyroiditis
0.000 0.588 0.412
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.588 0.412
E06.0 Acute thyroiditis
0.000 0.588 0.412
E06.5 Other chronic thyroiditis
0.000 0.591 0.408
E14.5 With peripheral circulatory complications
0.000 0.595 0.404
C25 Malignant neoplasm of pancreas
0.000 0.598 0.402
E07.1 Dyshormogenetic goitre
0.000 0.600 0.400
E07.0 Hypersecretion of calcitonin
0.000 0.600 0.400
C17 Malignant neoplasm of small intestine
0.000 0.600 0.400
E14.2 Withrenal complications
0.000 0.608 0.391
K90 Intestinal malabsorption
0.000 0.610 0.390
E14.0 With coma
0.000 0.613 0.387
C15.5 Lower third of oesophagus
0.000 0.613 0.387
C15.0 Cervical part of oesophagus
0.000 0.614 0.385
E44.1 Mild protein-energy malnutrition
0.000 0.615 0.385
E44.0 Moderate protein-energy malnutrition
0.000 0.615 0.385
C17.0 Duodenum
0.000 0.616 0.384
C15.9 Oesophagus, unspecified
0.000 0.626 0.374
C15.4 Middle third of oesophagus
0.000 0.627 0.373
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.641 0.359
C15.3 Upper third of oesophagus
0.000 0.648 0.352
C25.2 Tail of pancreas
0.000 0.660 0.340
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.666 0.334
C15.1 Thoracic part of oesophagus
0.000 0.668 0.332
C25.3 Pancreatic duct
0.000 0.670 0.330
C15.8 Overlapping lesion of oesophagus
0.000 0.670 0.330
C15.2 Abdominal part of oesophagus
0.000 0.670 0.330
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.671 0.329
C21 Malignant neoplasm of anus and anal canal
0.000 0.676 0.324
C25.4 Endocrine pancreas
0.000 0.680 0.320
C25.1 Body of pancreas
0.000 0.681 0.319
C25.8 Overlapping lesion of pancreas
0.000 0.689 0.311
E50-E64 Other nutritional deficiencies
0.000 0.690 0.310
E65-E68 Obesity and other hyperalimentation
0.000 0.709 0.291
E03 Other hypothyroidism
0.000 0.709 0.291
C24.0 Extrahepatic bile duct
0.000 0.712 0.287
C17.8 Overlapping lesion of small intestine
0.000 0.713 0.287
C17.3 Meckel's diverticulum
0.000 0.713 0.287
C25.9 Pancreas, unspecified
0.000 0.717 0.283
K90.3 Pancreatic steatorrhoea
0.000 0.720 0.279
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.720 0.279
K90.1 Tropical sprue
0.000 0.720 0.279
C17.1 Jejunum
0.000 0.736 0.264
K90.8 Other intestinal malabsorption
0.000 0.738 0.262
C25.7 Other parts of pancreas
0.000 0.741 0.259
E11 Non-insulin-dependent diabetes mellitus
0.000 0.745 0.255
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.745 0.254
C23 Malignant neoplasm of gallbladder
0.000 0.750 0.250
C24.8 Overlapping lesion of biliary tract
0.000 0.761 0.239
E11.6 With other specified complications
0.000 0.766 0.234
E54 Ascorbic acid deficiency
0.000 0.767 0.233
C21.2 Cloacogenic zone
0.000 0.768 0.232
C24.9 Biliary tract, unspecified
0.000 0.769 0.231
C17.9 Small intestine, unspecified
0.000 0.776 0.224
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.778 0.222
E63 Other nutritional deficiencies
0.000 0.778 0.222
E50 Vitamin A deficiency
0.000 0.778 0.222
E60 Dietary zinc deficiency
0.000 0.778 0.222
E59 Dietary selenium deficiency
0.000 0.778 0.222
E52 Niacin deficiency [pellagra]
0.000 0.778 0.222
E11.1 With ketoacidosis
0.000 0.780 0.220
E51 Thiamine deficiency
0.000 0.781 0.219
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.784 0.216
E56 Other vitamin deficiencies
0.000 0.785 0.215
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.786 0.214
C21.0 Anus, unspecified
0.000 0.787 0.213
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.789 0.211
E67 Other hyperalimentation
0.000 0.791 0.209
E68 Sequelae of hyperalimentation
0.000 0.791 0.209
E03.5 Myxoedema coma
0.000 0.791 0.208
E03.4 Atrophy of thyroid (acquired)
0.000 0.791 0.208
E03.3 Postinfectious hypothyroidism
0.000 0.791 0.208
E11.0 With coma
0.000 0.794 0.206
E07.9 Disorder of thyroid, unspecified
0.000 0.798 0.202
C21.1 Anal canal
0.000 0.799 0.201
E03.1 Congenital hypothyroidism without goitre
0.000 0.801 0.199
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.804 0.196
E58 Dietary calcium deficiency
0.000 0.809 0.191
C17.2 Ileum
0.000 0.812 0.187
E55 Vitamin D deficiency
0.000 0.814 0.186
E11.2 With renal complications
0.000 0.816 0.184
E11.7 With multiple complications
0.000 0.817 0.183
K90.9 Intestinal malabsorption, unspecified
0.000 0.817 0.183
E03.8 Other specified hypothyroidism
0.000 0.823 0.177
E53 Deficiency of other B group vitamins
0.000 0.825 0.175
E06.3 Autoimmune thyroiditis
0.000 0.836 0.164
E61 Deficiency of other nutrient elements
0.000 0.839 0.161
E50.9 Vitamin A deficiency, unspecified
0.000 0.840 0.159
E50.8 Other manifestations of vitamin A deficiency
0.000 0.840 0.159
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.840 0.159
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.840 0.159
E50.5 Vitamin A deficiency with night blindness
0.000 0.840 0.159
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.840 0.159
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.840 0.159
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.840 0.159
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.840 0.159
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.840 0.159
E63.9 Nutritional deficiency, unspecified
0.000 0.840 0.159
E63.8 Other specified nutritional deficiencies
0.000 0.840 0.159
E63.1 Imbalance of constituents of food intake
0.000 0.840 0.159
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.840 0.159
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.840 0.159
E64.8 Sequelae of other nutritional deficiencies
0.000 0.840 0.159
E64.3 Sequelae of rickets
0.000 0.840 0.159
E64.2 Sequelae of vitamin C deficiency
0.000 0.840 0.159
E64.1 Sequelae of vitamin A deficiency
0.000 0.840 0.159
E64.0 Sequelae of protein-energy malnutrition
0.000 0.840 0.159
E51.9 Thiamine deficiency, unspecified
0.000 0.842 0.157
E51.8 Other manifestations of thiamine deficiency
0.000 0.842 0.157
E51.1 Beriberi
0.000 0.842 0.157
E51.2 Wernicke's encephalopathy
0.000 0.846 0.154
E56.9 Vitamin deficiency, unspecified
0.000 0.846 0.154
E56.8 Deficiency of other vitamins
0.000 0.846 0.154
E56.0 Deficiency of vitamin E
0.000 0.846 0.154
C22.7 Other specified carcinomas of liver
0.000 0.846 0.154
C22.4 Other sarcomas of liver
0.000 0.846 0.154
C22.3 Angiosarcoma of liver
0.000 0.846 0.154
C22.2 Hepatoblastoma
0.000 0.846 0.154
E65 Localised adiposity
0.000 0.846 0.154
E11.8 With unspecified complications
0.000 0.848 0.152
C26.8 Overlapping lesion of digestive system
0.000 0.848 0.151
C26.1 Spleen
0.000 0.848 0.151
C22.9 Liver, unspecified
0.000 0.849 0.150
E67.8 Other specified hyperalimentation
0.000 0.850 0.150
E67.3 Hypervitaminosis D
0.000 0.850 0.150
E67.2 Megavitamin-B6 syndrome
0.000 0.850 0.150
E67.1 Hypercarotenaemia
0.000 0.850 0.150
E67.0 Hypervitaminosis A
0.000 0.850 0.150
E83 Disorders of mineral metabolism
0.116 0.852 0.032
E56.1 Deficiency of vitamin K
0.000 0.853 0.146
C22.1 Intrahepatic bile duct carcinoma
0.000 0.856 0.144
E53.9 Vitamin B deficiency, unspecified
0.000 0.860 0.140
C24.1 Ampulla of Vater
0.001 0.861 0.138
E55.0 Rickets, active
0.000 0.867 0.133
E14.9 Without complications
0.000 0.871 0.129
E53.1 Pyridoxine deficiency
0.000 0.874 0.125
E53.0 Riboflavin deficiency
0.000 0.874 0.125
E70-E90 Metabolic disorders
0.001 0.880 0.118
E11.5 With peripheral circulatory complications
0.000 0.882 0.118
C18 Malignant neoplasm of colon
0.000 0.883 0.117
E61.9 Deficiency of nutrient element, unspecified
0.000 0.884 0.116
E61.8 Deficiency of other specified nutrient elements
0.000 0.884 0.116
E61.7 Deficiency of multiple nutrient elements
0.000 0.884 0.116
E61.6 Vanadium deficiency
0.000 0.884 0.116
E61.5 Molybdenum deficiency
0.000 0.884 0.116
E61.4 Chromium deficiency
0.000 0.884 0.116
E61.3 Manganese deficiency
0.000 0.884 0.116
E61.0 Copper deficiency
0.000 0.884 0.116
R31 Unspecified haematuria
0.114 0.886 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.886 0.114
C25.0 Head of pancreas
0.000 0.887 0.113
C18.1 Appendix
0.000 0.887 0.113
E78.2 Mixed hyperlipidaemia
0.000 0.888 0.112
C18.9 Colon, unspecified
0.000 0.892 0.108
E83.8 Other disorders of mineral metabolism
0.083 0.894 0.023
E83.2 Disorders of zinc metabolism
0.083 0.894 0.023
E83.0 Disorders of copper metabolism
0.083 0.894 0.023
E83.9 Disorder of mineral metabolism, unspecified
0.084 0.894 0.022
E61.2 Magnesium deficiency
0.000 0.895 0.105
C26.9 Ill-defined sites within the digestive system
0.001 0.895 0.104
C26.0 Intestinal tract, part unspecified
0.000 0.897 0.103
C16 Malignant neoplasm of stomach
0.000 0.898 0.102
E78.1 Pure hyperglyceridaemia
0.000 0.898 0.102
E83.3 Disorders of phosphorus metabolism
0.090 0.900 0.010
E55.9 Vitamin D deficiency, unspecified
0.000 0.904 0.096
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.905 0.094
E78.6 Lipoprotein deficiency
0.000 0.909 0.091
E88 Other metabolic disorders
0.000 0.909 0.090
E84 Cystic fibrosis
0.001 0.910 0.089
E78.5 Hyperlipidaemia, unspecified
0.000 0.912 0.088
E73 Lactose intolerance
0.001 0.913 0.086
E77 Disorders of glycoprotein metabolism
0.001 0.914 0.085
E76 Disorders of glycosaminoglycan metabolism
0.001 0.914 0.085
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.914 0.085
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.914 0.085
E78.3 Hyperchylomicronaemia
0.000 0.914 0.086
C18.8 Overlapping lesion of colon
0.000 0.915 0.085
E74 Other disorders of carbohydrate metabolism
0.001 0.916 0.083
M45.X9 Ankylosing spondylitis (Site unspecified)
0.081 0.919 0.000
E70 Disorders of aromatic amino-acid metabolism
0.001 0.919 0.080
E79 Disorders of purine and pyrimidine metabolism
0.001 0.920 0.078
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.921 0.079
E88.9 Metabolic disorder, unspecified
0.000 0.922 0.078
E72 Other disorders of amino-acid metabolism
0.001 0.922 0.076
C16.0 Cardia
0.000 0.923 0.077
I83 Varicose veins of lower extremities
0.076 0.924 0.000
E61.1 Iron deficiency
0.000 0.925 0.075
E75.5 Other lipid storage disorders
0.001 0.925 0.074
E85 Amyloidosis
0.001 0.926 0.073
E75.2 Other sphingolipidosis
0.001 0.929 0.071
C16.2 Body of stomach
0.000 0.929 0.071
C18.4 Transverse colon
0.000 0.929 0.071
C16.6 Greater curvature of stomach, unspecified
0.000 0.930 0.070
E78.4 Other hyperlipidaemia
0.000 0.931 0.069
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.931 0.068
E75.6 Lipid storage disorder, unspecified
0.001 0.932 0.067
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.932 0.067
E75.3 Sphingolipidosis, unspecified
0.001 0.932 0.067
E75.1 Other gangliosidosis
0.001 0.932 0.067
E75.0 GM2 gangliosidosis
0.001 0.932 0.067
E84.9 Cystic fibrosis, unspecified
0.001 0.932 0.067
C18.6 Descending colon
0.000 0.932 0.068
E20-E35 Disorders of other endocrine glands
0.000 0.934 0.066
C16.5 Lesser curvature of stomach, unspecified
0.000 0.934 0.066
E11.4 With neurological complications
0.000 0.934 0.066
C16.1 Fundus of stomach
0.000 0.934 0.065
E88.2 Lipomatosis, not elsewhere classified
0.000 0.934 0.065
E84.8 Cystic fibrosis with other manifestations
0.001 0.935 0.064
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.935 0.064
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.935 0.064
C16.8 Overlapping lesion of stomach
0.000 0.936 0.064
E88.8 Other specified metabolic disorders
0.000 0.937 0.063
E73.9 Lactose intolerance, unspecified
0.001 0.937 0.063
E73.8 Other lactose intolerance
0.001 0.938 0.062
E73.1 Secondary lactase deficiency
0.001 0.938 0.062
E73.0 Congenital lactase deficiency
0.001 0.938 0.062
E71.3 Disorders of fatty-acid metabolism
0.001 0.938 0.061
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.938 0.061
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.938 0.061
E71.0 Maple-syrup-urine disease
0.001 0.938 0.061
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.938 0.061
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.938 0.061
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.938 0.061
E76.2 Other mucopolysaccharidoses
0.001 0.938 0.061
E76.1 Mucopolysaccharidosis, type II
0.001 0.938 0.061
E76.0 Mucopolysaccharidosis, type I
0.001 0.938 0.061
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.938 0.061
E77.8 Other disorders of glycoprotein metabolism
0.001 0.938 0.061
E77.1 Defects in glycoprotein degradation
0.001 0.938 0.061
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.938 0.061
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.939 0.060
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.939 0.060
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.939 0.060
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.939 0.060
E74.2 Disorders of galactose metabolism
0.001 0.939 0.060
E74.1 Disorders of fructose metabolism
0.001 0.939 0.060
C22.0 Liver cell carcinoma
0.001 0.940 0.060
C18.3 Hepatic flexure
0.000 0.940 0.060
C16.4 Pylorus
0.000 0.940 0.060
E78.8 Other disorders of lipoprotein metabolism
0.000 0.941 0.059
E88.3 Tumour lysis syndrome
0.001 0.941 0.058
E74.0 Glycogen storage disease
0.001 0.941 0.058
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.941 0.057
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.941 0.057
E70.2 Disorders of tyrosine metabolism
0.001 0.941 0.057
E70.1 Other hyperphenylalaninaemias
0.001 0.941 0.057
E70.0 Classical phenylketonuria
0.001 0.941 0.057
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.943 0.056
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.943 0.056
E79.1 Lesch-Nyhan syndrome
0.001 0.943 0.056
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.944 0.055
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.944 0.055
E72.5 Disorders of glycine metabolism
0.001 0.944 0.055
E72.4 Disorders of ornithine metabolism
0.001 0.944 0.055
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.944 0.055
E72.2 Disorders of urea cycle metabolism
0.001 0.944 0.055
E85.4 Organ-limited amyloidosis
0.001 0.944 0.055
E24 Cushing's syndrome
0.000 0.944 0.056
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.945 0.055
E85.3 Secondary systemic amyloidosis
0.001 0.945 0.054
C16.3 Pyloric antrum
0.000 0.945 0.054
E72.0 Disorders of amino-acid transport
0.001 0.946 0.053
E70.3 Albinism
0.001 0.946 0.053
E85.8 Other amyloidosis
0.001 0.946 0.053
E83.4 Disorders of magnesium metabolism
0.040 0.946 0.014
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.946 0.053
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.946 0.053
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.946 0.053
E78.0 Pure hypercholesterolaemia
0.000 0.948 0.052
I83.0 Varicose veins of lower extremities with ulcer
0.052 0.948 0.000
E20 Hypoparathyroidism
0.000 0.949 0.051
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.949 0.050
C16.9 Stomach, unspecified
0.000 0.949 0.051
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.949 0.050
C18.7 Sigmoid colon
0.000 0.950 0.050
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.950 0.049
E31 Polyglandular dysfunction
0.000 0.951 0.049
E28 Ovarian dysfunction
0.000 0.951 0.049
E25 Adrenogenital disorders
0.000 0.952 0.048
E04 Other non-toxic goitre
0.000 0.952 0.047
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.952 0.047
E32 Diseases of thymus
0.000 0.952 0.047
E30 Disorders of puberty, not elsewhere classified
0.000 0.952 0.047
E11.3 With ophthalmic complications
0.000 0.953 0.047
E86 Volume depletion
0.000 0.954 0.046
E24.0 Pituitary-dependent Cushing's disease
0.000 0.954 0.046
E24.9 Cushing's syndrome, unspecified
0.000 0.956 0.044
E29 Testicular dysfunction
0.000 0.958 0.042
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.959 0.041
E80.2 Other porphyria
0.001 0.959 0.040
E24.8 Other Cushing's syndrome
0.000 0.959 0.040
E20.9 Hypoparathyroidism, unspecified
0.000 0.960 0.040
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.960 0.040
E24.3 Ectopic ACTH syndrome
0.000 0.960 0.040
E24.1 Nelson's syndrome
0.000 0.960 0.040
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.040 0.960 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.960 0.040
E28.2 Polycystic ovarian syndrome
0.000 0.962 0.038
E53.8 Deficiency of other specified B group vitamins
0.000 0.963 0.037
E31.0 Autoimmune polyglandular failure
0.000 0.963 0.037
E20.8 Other hypoparathyroidism
0.000 0.963 0.037
E20.1 Pseudohypoparathyroidism
0.000 0.963 0.037
E20.0 Idiopathic hypoparathyroidism
0.000 0.963 0.037
E21.3 Hyperparathyroidism, unspecified
0.000 0.963 0.037
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.963 0.036
E80.5 Crigler-Najjar syndrome
0.001 0.963 0.036
E80.3 Defects of catalase and peroxydase
0.001 0.963 0.036
E80.0 Hereditary erythropoietic porphyria
0.001 0.963 0.036
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.964 0.036
M45 Ankylosing spondylitis
0.036 0.964 0.000
E31.9 Polyglandular dysfunction, unspecified
0.000 0.964 0.035
E31.8 Other polyglandular dysfunction
0.000 0.964 0.035
E31.1 Polyglandular hyperfunction
0.000 0.964 0.035
E28.9 Ovarian dysfunction, unspecified
0.000 0.965 0.035
E28.8 Other ovarian dysfunction
0.000 0.965 0.035
E28.1 Androgen excess
0.000 0.965 0.035
E28.0 Oestrogen excess
0.000 0.965 0.035
E25.9 Adrenogenital disorder, unspecified
0.000 0.965 0.035
E25.8 Other adrenogenital disorders
0.000 0.965 0.035
E04.8 Other specified non-toxic goitre
0.000 0.965 0.034
E30.9 Disorder of puberty, unspecified
0.000 0.966 0.034
E30.8 Other disorders of puberty
0.000 0.966 0.034
E30.1 Precocious puberty
0.000 0.966 0.034
E30.0 Delayed puberty
0.000 0.966 0.034
E32.9 Disease of thymus, unspecified
0.000 0.966 0.034
E32.8 Other diseases of thymus
0.000 0.966 0.034
E32.1 Abscess of thymus
0.000 0.966 0.034
E32.0 Persistent hyperplasia of thymus
0.000 0.966 0.034
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.966 0.034
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.966 0.034
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.966 0.034
E85.9 Amyloidosis, unspecified
0.001 0.966 0.033
E28.3 Primary ovarian failure
0.000 0.966 0.034
I83.1 Varicose veins of lower extremities with inflammation
0.033 0.967 0.000
E34 Other endocrine disorders
0.000 0.968 0.032
E26 Hyperaldosteronism
0.000 0.968 0.031
E80.1 Porphyria cutanea tarda
0.001 0.968 0.031
E29.9 Testicular dysfunction, unspecified
0.000 0.969 0.031
E80.6 Other disorders of bilirubin metabolism
0.001 0.969 0.030
E29.8 Other testicular dysfunction
0.000 0.970 0.030
E29.0 Testicular hyperfunction
0.000 0.970 0.030
I73 Other peripheral vascular diseases
0.000 0.970 0.030
I73.9 Peripheral vascular disease, unspecified
0.000 0.970 0.030
E21.4 Other specified disorders of parathyroid gland
0.000 0.970 0.029
E21.2 Other hyperparathyroidism
0.000 0.971 0.029
I73.0 Raynaud's syndrome
0.000 0.971 0.029
I77 Other disorders of arteries and arterioles
0.000 0.971 0.029
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.972 0.028
M45.X6 Ankylosing spondylitis (Lumbar region)
0.028 0.972 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.972 0.028
I77.6 Arteritis, unspecified
0.000 0.972 0.028
E83.5 Disorders of calcium metabolism
0.004 0.973 0.023
E22 Hyperfunction of pituitary gland
0.000 0.973 0.027
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.974 0.026
M45.X2 Ankylosing spondylitis (Cervical region)
0.026 0.974 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.026 0.974 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.026 0.974 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.026 0.974 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.026 0.974 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.026 0.974 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.026 0.974 0.000
I72 Other aneurysm
0.000 0.974 0.026
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.975 0.025
I74 Arterial embolism and thrombosis
0.000 0.975 0.025
E29.1 Testicular hypofunction
0.000 0.976 0.024
K90-K93 Other diseases of the digestive system
0.000 0.976 0.024
I74.5 Embolism and thrombosis of iliac artery
0.000 0.976 0.024
I77.8 Other specified disorders of arteries and arterioles
0.000 0.976 0.024
E04.0 Non-toxic diffuse goitre
0.001 0.976 0.024
C18.5 Splenic flexure
0.001 0.976 0.023
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.976 0.024
C18.2 Ascending colon
0.000 0.976 0.024
E34.3 Short stature, not elsewhere classified
0.000 0.976 0.023
E34.5 Androgen resistance syndrome
0.000 0.977 0.023
E34.4 Constitutional tall stature
0.000 0.977 0.023
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.977 0.023
E34.1 Other hypersecretion of intestinal hormones
0.000 0.977 0.023
E26.8 Other hyperaldosteronism
0.000 0.977 0.023
E26.1 Secondary hyperaldosteronism
0.000 0.977 0.023
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.977 0.023
I72.4 Aneurysm of artery of lower extremity
0.000 0.977 0.023
I73.8 Other specified peripheral vascular diseases
0.000 0.977 0.023
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.978 0.022
I77.2 Rupture of artery
0.000 0.978 0.022
I72.0 Aneurysm of carotid artery
0.000 0.978 0.022
I77.3 Arterial fibromuscular dysplasia
0.000 0.978 0.022
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.979 0.021
I70 Atherosclerosis
0.000 0.979 0.021
E23 Hypofunction and other disorders of pituitary gland
0.000 0.979 0.021
E66 Obesity
0.000 0.979 0.021
I77.5 Necrosis of artery
0.000 0.979 0.021
I77.4 Coeliac artery compression syndrome
0.000 0.979 0.021
E87.7 Fluid overload
0.000 0.979 0.021
E34.8 Other specified endocrine disorders
0.000 0.980 0.020
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.020 0.980 0.000
I72.3 Aneurysm of iliac artery
0.000 0.980 0.020
I72.1 Aneurysm of artery of upper extremity
0.000 0.980 0.020
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.980 0.020
E26.9 Hyperaldosteronism, unspecified
0.000 0.980 0.020
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.980 0.020
I78 Diseases of capillaries
0.000 0.980 0.020
E22.8 Other hyperfunction of pituitary gland
0.000 0.980 0.020
E34.0 Carcinoid syndrome
0.000 0.980 0.019
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.981 0.019
E34.9 Endocrine disorder, unspecified
0.000 0.981 0.019
I72.9 Aneurysm of unspecified site
0.000 0.981 0.019
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.981 0.019
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.981 0.019

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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