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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12349081
log Bayes Factor = 0.551151
Chromosome 9   position 21,951,902  (GRCh37) Explore rs12349081 on Ensembl!
Variant rs12349081 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44 Other malignant neoplasms of skin
0.000 0.316 0.684
C44.4 Skin of scalp and neck
0.000 0.322 0.678
C44.1 Skin of eyelid, including canthus
0.000 0.347 0.653
C44.3 Skin of other and unspecified parts of face
0.000 0.349 0.651
C44.2 Skin of ear and external auricular canal
0.000 0.349 0.651
C44.5 Skin of trunk
0.000 0.393 0.607
C44.6 Skin of upper limb, including shoulder
0.000 0.431 0.569
C44.0 Skin of lip
0.000 0.447 0.553
C44.8 Overlapping lesion of skin
0.000 0.510 0.490
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.555 0.445
C44.7 Skin of lower limb, including hip
0.000 0.778 0.222
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.877 0.123
C50 Malignant neoplasm of breast
0.069 0.931 0.000
C50.1 Central portion of breast
0.066 0.934 0.000
C50.9 Breast, unspecified
0.065 0.935 0.000
C50.5 Lower-outer quadrant of breast
0.064 0.936 0.000
C50.4 Upper-outer quadrant of breast
0.064 0.936 0.000
C50.3 Lower-inner quadrant of breast
0.059 0.941 0.000
C50.8 Overlapping lesion of breast
0.053 0.947 0.000
C50.0 Nipple and areola
0.052 0.948 0.000
I73.0 Raynaud's syndrome
0.050 0.950 0.000
C50.6 Axillary tail of breast
0.049 0.951 0.000
C50.2 Upper-inner quadrant of breast
0.039 0.960 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.970 0.030
C50-C50 Malignant neoplasm of breast
0.029 0.971 0.000
I25 Chronic ischaemic heart disease
0.000 0.975 0.025
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.976 0.024
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.979 0.021
I25.2 Old myocardial infarction
0.000 0.979 0.021
E83.1 Disorders of iron metabolism
0.000 0.980 0.020
I73 Other peripheral vascular diseases
0.011 0.980 0.008
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.981 0.019
I71 Aortic aneurysm and dissection
0.000 0.981 0.019
J34.8 Other specified disorders of nose and nasal sinuses
0.018 0.982 0.000
I25.6 Silent myocardial ischaemia
0.000 0.982 0.018
I25.4 Coronary artery aneurysm
0.000 0.983 0.017
I25.5 Ischaemic cardiomyopathy
0.000 0.983 0.017
I25.1 Atherosclerotic heart disease
0.000 0.983 0.017
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.984 0.016
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.984 0.016
I77 Other disorders of arteries and arterioles
0.000 0.985 0.015
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.985 0.015
I25.3 Aneurysm of heart
0.000 0.985 0.015
I73.1 Thromboangiitis obliterans [Buerger]
0.008 0.986 0.006
I77.1 Stricture of artery
0.000 0.986 0.014
I73.8 Other specified peripheral vascular diseases
0.009 0.986 0.005
I71.0 Dissection of aorta [any part]
0.000 0.986 0.014
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.986 0.014
J34 Other disorders of nose and nasal sinuses
0.014 0.986 0.000
I74 Arterial embolism and thrombosis
0.000 0.986 0.014
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.986 0.014
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.986 0.014
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.986 0.014
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.986 0.014
J34.3 Hypertrophy of nasal turbinates
0.014 0.986 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.986 0.013
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.987 0.013
I70 Atherosclerosis
0.000 0.987 0.013
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.988 0.012
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.988 0.012
I77.0 Arteriovenous fistula, acquired
0.000 0.989 0.011
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.989 0.011
I77.5 Necrosis of artery
0.000 0.989 0.011
I77.4 Coeliac artery compression syndrome
0.000 0.989 0.011
I77.3 Arterial fibromuscular dysplasia
0.000 0.989 0.011
I77.2 Rupture of artery
0.000 0.989 0.011
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.989 0.011
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.989 0.011
J34.1 Cyst and mucocele of nose and nasal sinus
0.011 0.989 0.000
J30-J39 Other diseases of upper respiratory tract
0.010 0.990 0.000
J33.8 Other polyp of sinus
0.010 0.990 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.990 0.010
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.990 0.010
J34.0 Abscess, furuncle and carbuncle of nose
0.010 0.990 0.000
I78 Diseases of capillaries
0.000 0.990 0.010
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.990 0.010
I79.1 Aortitis in diseases classified elsewhere
0.000 0.990 0.010
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.990 0.010
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.990 0.010
I77.6 Arteritis, unspecified
0.000 0.990 0.010
J33 Nasal polyp
0.010 0.990 0.000
C43 Malignant melanoma of skin
0.001 0.990 0.009
I74.8 Embolism and thrombosis of other arteries
0.000 0.990 0.009
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.990 0.009
I70.9 Generalised and unspecified atherosclerosis
0.000 0.991 0.009
I70.8 Atherosclerosis of other arteries
0.000 0.991 0.009
I70.0 Atherosclerosis of aorta
0.000 0.991 0.009
I20.9 Angina pectoris, unspecified
0.000 0.991 0.009
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.009 0.991 0.000
I74.5 Embolism and thrombosis of iliac artery
0.000 0.991 0.008
J35 Chronic diseases of tonsils and adenoids
0.009 0.991 0.000
J37 Chronic laryngitis and laryngotracheitis
0.009 0.991 0.000
I77.8 Other specified disorders of arteries and arterioles
0.000 0.991 0.008
I70.1 Atherosclerosis of renal artery
0.000 0.992 0.008
J36 Peritonsillar abscess
0.008 0.992 0.000
J35.1 Hypertrophy of tonsils
0.008 0.992 0.000
J30 Vasomotor and allergic rhinitis
0.008 0.992 0.000
I72 Other aneurysm
0.000 0.992 0.008
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.992 0.008
E83 Disorders of mineral metabolism
0.000 0.992 0.008
I73.9 Peripheral vascular disease, unspecified
0.000 0.992 0.007
C18.7 Sigmoid colon
0.000 0.992 0.008
I78.9 Disease of capillaries, unspecified
0.000 0.992 0.007
I78.8 Other diseases of capillaries
0.000 0.992 0.007
J39 Other diseases of upper respiratory tract
0.007 0.993 0.000
I20 Angina pectoris
0.000 0.993 0.007
C43.4 Malignant melanoma of scalp and neck
0.001 0.993 0.007
I78.1 Naevus, nonneoplastic
0.000 0.993 0.007
J37.0 Chronic laryngitis
0.007 0.993 0.000
J33.1 Polypoid sinus degeneration
0.007 0.993 0.000
J30.3 Other allergic rhinitis
0.007 0.993 0.000
C43.8 Overlapping malignant melanoma of skin
0.001 0.993 0.007
C43.1 Malignant melanoma of eyelid, including canthus
0.001 0.993 0.007
C43.0 Malignant melanoma of lip
0.001 0.993 0.007
I20-I25 Ischaemic heart diseases
0.000 0.993 0.007
C43.9 Malignant melanoma of skin, unspecified
0.001 0.993 0.007
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.993 0.007
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.993 0.007
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.993 0.007
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.993 0.007
J31.2 Chronic pharyngitis
0.007 0.993 0.000
C67.9 Bladder, unspecified
0.000 0.993 0.007
J31.0 Chronic rhinitis
0.007 0.993 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.993 0.007
H33.2 Serous retinal detachment
0.007 0.993 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.001 0.993 0.006
J33.9 Nasal polyp, unspecified
0.007 0.993 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.993 0.007
H25.0 Senile incipient cataract
0.000 0.993 0.007
H02.1 Ectropion of eyelid
0.000 0.993 0.007
I72.3 Aneurysm of iliac artery
0.000 0.993 0.006
J35.0 Chronic tonsillitis
0.007 0.993 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.993 0.006
D35.1 Parathyroid gland
0.006 0.994 0.000
J31.1 Chronic nasopharyngitis
0.006 0.994 0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.006 0.994 0.000
J35.2 Hypertrophy of adenoids
0.006 0.994 0.000
J37.1 Chronic laryngotracheitis
0.006 0.994 0.000
J30.0 Vasomotor rhinitis
0.006 0.994 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.006 0.994 0.000
J39.8 Other specified diseases of upper respiratory tract
0.006 0.994 0.000
J39.9 Disease of upper respiratory tract, unspecified
0.006 0.994 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.994 0.006
J30.2 Other seasonal allergic rhinitis
0.006 0.994 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.994 0.006
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.994 0.006
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.994 0.006
I72.1 Aneurysm of artery of upper extremity
0.000 0.994 0.006
I20.1 Angina pectoris with documented spasm
0.000 0.994 0.006
I20.0 Unstable angina
0.000 0.994 0.006
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.994 0.006
E83.8 Other disorders of mineral metabolism
0.000 0.994 0.006
E83.2 Disorders of zinc metabolism
0.000 0.994 0.006
E83.0 Disorders of copper metabolism
0.000 0.994 0.006
H02.8 Other specified disorders of eyelid
0.000 0.994 0.006
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.006 0.994 0.000
M67.8 Other specified disorders of synovium and tendon
0.000 0.994 0.006
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.000 0.994 0.006
H02.4 Ptosis of eyelid
0.000 0.994 0.006
H02 Other disorders of eyelid
0.000 0.994 0.006
J33.0 Polyp of nasal cavity
0.006 0.994 0.000
I72.4 Aneurysm of artery of lower extremity
0.000 0.994 0.005
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.994 0.006
I72.9 Aneurysm of unspecified site
0.000 0.994 0.005
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified
0.005 0.994 0.000
J39.1 Other abscess of pharynx
0.005 0.994 0.000
J39.0 Retropharyngeal and parapharyngeal abscess
0.005 0.994 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.000 0.994 0.006
N35.9 Urethral stricture, unspecified
0.006 0.994 0.000
I08.8 Other multiple valve diseases
0.000 0.995 0.005
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.995 0.005
I23 Certain current complications following acute myocardial infarction
0.000 0.995 0.005
J30.4 Allergic rhinitis, unspecified
0.005 0.995 0.000
I08 Multiple valve diseases
0.000 0.995 0.005
E83.4 Disorders of magnesium metabolism
0.000 0.995 0.005
I72.2 Aneurysm of renal artery
0.000 0.995 0.005
J35.8 Other chronic diseases of tonsils and adenoids
0.005 0.995 0.000
H66.9 Otitis media, unspecified
0.005 0.995 0.000
I72.0 Aneurysm of carotid artery
0.000 0.995 0.005
J38.3 Other diseases of vocal cords
0.005 0.995 0.000
J38.0 Paralysis of vocal cords and larynx
0.005 0.995 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.995 0.005
J30.1 Allergic rhinitis due to pollen
0.005 0.995 0.000
I72.8 Aneurysm of other specified arteries
0.000 0.995 0.005
J38.5 Laryngeal spasm
0.005 0.995 0.000
J38.6 Stenosis of larynx
0.005 0.995 0.000
H02.9 Disorder of eyelid, unspecified
0.000 0.995 0.005
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.995 0.005
J38.4 Oedema of larynx
0.005 0.995 0.000
E83.5 Disorders of calcium metabolism
0.000 0.995 0.005
C43.3 Malignant melanoma of other and unspecified parts of face
0.001 0.995 0.004
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.995 0.005
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.995 0.005
H66 Suppurative and unspecified otitis media
0.005 0.995 0.000
M67 Other disorders of synovium and tendon
0.000 0.995 0.005
H02.2 Lagophthalmos
0.000 0.996 0.004
J32 Chronic sinusitis
0.004 0.996 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.004 0.996 0.000
I05-I09 Chronic rheumatic heart diseases
0.000 0.996 0.004
J32.0 Chronic maxillary sinusitis
0.004 0.996 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.996 0.004
C67 Malignant neoplasm of bladder
0.000 0.996 0.004
C67.2 Lateral wall of bladder
0.000 0.996 0.004
J38.1 Polyp of vocal cord and larynx
0.004 0.996 0.000
J38.2 Nodules of vocal cords
0.004 0.996 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.996 0.004
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.996 0.004
I23.8 Other current complications following acute myocardial infarction
0.000 0.996 0.004
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.996 0.004
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.996 0.004
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.996 0.004
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.996 0.004
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.996 0.004
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.996 0.004
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.996 0.004
I08.9 Multiple valve disease, unspecified
0.000 0.996 0.004
Z43.0 Attention to tracheostomy
0.004 0.996 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.996 0.004
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.996 0.004
H02.5 Other disorders affecting eyelid function
0.000 0.996 0.004
I07 Rheumatic tricuspid valve diseases
0.000 0.996 0.004
H25 Senile cataract
0.000 0.996 0.004
H25.8 Other senile cataract
0.000 0.996 0.004
H66.2 Chronic atticoantral suppurative otitis media
0.004 0.996 0.000
H72 Perforation of tympanic membrane
0.004 0.996 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.996 0.004
M67.1 Other contracture of tendon (sheath)
0.000 0.996 0.004
C67.1 Dome of bladder
0.000 0.996 0.004
H02.6 Xanthelasma of eyelid
0.000 0.996 0.004
H02.0 Entropion and trichiasis of eyelid
0.000 0.996 0.004
C43.7 Malignant melanoma of lower limb, including hip
0.001 0.996 0.003
H65-H75 Diseases of middle ear and mastoid
0.004 0.996 0.000
H66.3 Other chronic suppurative otitis media
0.004 0.996 0.000
I07.1 Tricuspid insufficiency
0.000 0.996 0.004
C15.5 Lower third of oesophagus
0.000 0.996 0.004
D22.7 Melanocytic naevi of lower limb, including hip
0.004 0.996 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.000 0.996 0.004
Chapter IX Diseases of the circulatory system
0.000 0.996 0.004
H65.4 Other chronic nonsuppurative otitis media
0.004 0.996 0.000
H66.4 Suppurative otitis media, unspecified
0.003 0.996 0.000
H66.0 Acute suppurative otitis media
0.003 0.996 0.000
Z43.5 Attention to cyctostomy
0.004 0.996 0.000
Z43 Attention to artificial openings
0.004 0.996 0.000
C43.5 Malignant melanoma of trunk
0.001 0.996 0.003
I12.0 Hypertensive renal disease with renal failure
0.000 0.996 0.004
M67.9 Disorder of synovium and tendon, unspecified
0.000 0.996 0.003
M67.4 Ganglion
0.000 0.996 0.003
M67.3 Transient synovitis
0.000 0.996 0.003
M67.0 Short Achilles tendon (acquired)
0.000 0.996 0.003
H66.1 Chronic tubotympanic suppurative otitis media
0.003 0.997 0.000
J32.3 Chronic sphenoidal sinusitis
0.003 0.997 0.000
J32.1 Chronic frontal sinusitis
0.003 0.997 0.000
H74 Other disorders of middle ear and mastoid
0.003 0.997 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.997 0.003
Z43.1 Attention to gastrostomy
0.003 0.997 0.000
I06 Rheumatic aortic valve diseases
0.000 0.997 0.003
C67.5 Bladder neck
0.000 0.997 0.003
J32.4 Chronic pansinusitis
0.003 0.997 0.000
C67.7 Urachus
0.000 0.997 0.003
C67.0 Trigone of bladder
0.000 0.997 0.003
I08.0 Disorders of both mitral and aortic valves
0.000 0.997 0.003
I09 Other rheumatic heart diseases
0.000 0.997 0.003
I24 Other acute ischaemic heart diseases
0.000 0.997 0.003
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.997 0.003
C67.3 Anterior wall of bladder
0.000 0.997 0.003
Z43.6 Attention to other artificial openings of urinary tract
0.003 0.997 0.000
Z43.2 Attention to ileostomy
0.003 0.997 0.000
H71 Cholesteatoma of middle ear
0.003 0.997 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.997 0.003
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.003 0.997 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.003 0.997 0.000
M65 Synovitis and tenosynovitis
0.000 0.997 0.003
I07.9 Tricuspid valve disease, unspecified
0.000 0.997 0.003
I07.8 Other tricuspid valve diseases
0.000 0.997 0.003
I07.2 Tricuspid stenosis with insufficiency
0.000 0.997 0.003
I07.0 Tricuspid stenosis
0.000 0.997 0.003
H25.2 Senile cataract, morgagnian type
0.000 0.997 0.003
H74.2 Discontinuity and dislocation of ear ossicles
0.003 0.997 0.000
M65-M68 Disorders of synovium and tendon
0.000 0.997 0.003
H02.3 Blepharochalasis
0.000 0.997 0.003
H72.8 Other perforations of tympanic membrane
0.003 0.997 0.000
K13.0 Diseases of lips
0.003 0.997 0.000
H33 Retinal detachments and breaks
0.003 0.997 0.000
H35.8 Other specified retinal disorders
0.000 0.997 0.003
J38.7 Other diseases of larynx
0.003 0.997 0.000
C67.8 Overlapping lesion of bladder
0.000 0.997 0.003
C67.6 Ureteric orifice
0.000 0.997 0.003
H72.2 Other marginal perforations of tympanic membrane
0.003 0.997 0.000
H72.1 Attic perforation of tympanic membrane
0.003 0.997 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.003 0.997 0.000
H33.4 Traction detachment of retina
0.003 0.997 0.000
R16.1 Splenomegaly, not elsewhere classified
0.000 0.997 0.003
H69 Other disorders of Eustachian tube
0.003 0.997 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.003 0.997 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.001 0.997 0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.003 0.997 0.000
H68 Eustachian salpingitis and obstruction
0.003 0.997 0.000
H67 Otitis media in diseases classified elsewhere
0.003 0.997 0.000
H74.4 Polyp of middle ear
0.003 0.997 0.000
H65 Nonsuppurative otitis media
0.003 0.997 0.000
N20.2 Calculus of kidney with calculus of ureter
0.003 0.997 0.000
I12 Hypertensive renal disease
0.000 0.997 0.003
I00-I02 Acute rheumatic fever
0.000 0.997 0.003
H33.3 Retinal breaks without detachment
0.003 0.997 0.000
H70 Mastoiditis and related conditions
0.003 0.997 0.000
Z43.9 Attention to unspecified artificial opening
0.003 0.997 0.000
Z43.7 Attention to artificial vagina
0.003 0.997 0.000
M67.49 Ganglion, multiple sites
0.000 0.997 0.003
M67.47 Ganglion, ankle and foot
0.000 0.997 0.003
M67.45 Ganglion, hip
0.000 0.997 0.003
M67.43 Ganglion, wrist
0.000 0.997 0.003
M67.96 Unspecified disorder of synovium and tendon, lower leg
0.000 0.997 0.003
H25.1 Senile nuclear cataract
0.000 0.997 0.003
C67.4 Posterior wall of bladder
0.000 0.997 0.003
H74.1 Adhesive middle ear disease
0.003 0.997 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.003 0.997 0.000
H26.9 Cataract, unspecified
0.000 0.997 0.003
H69.9 Eustachian tube disorder, unspecified
0.003 0.997 0.000
N35 Urethral stricture
0.003 0.997 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.003 0.997 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.997 0.002
I06.8 Other rheumatic aortic valve diseases
0.000 0.997 0.002
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.997 0.002
I06.1 Rheumatic aortic insufficiency
0.000 0.997 0.002
I06.0 Rheumatic aortic stenosis
0.000 0.997 0.002
S30.1 Contusion of abdominal wall
0.003 0.997 0.000
I09.8 Other specified rheumatic heart diseases
0.000 0.997 0.002
I09.2 Chronic rheumatic pericarditis
0.000 0.997 0.002
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.997 0.002
I09.0 Rheumatic myocarditis
0.000 0.997 0.002
M66 Spontaneous rupture of synovium and tendon
0.000 0.997 0.003
S30 Superficial injury of abdomen, lower back and pelvis
0.003 0.997 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.997 0.003
I05 Rheumatic mitral valve diseases
0.000 0.997 0.002
I09.9 Rheumatic heart disease, unspecified
0.000 0.997 0.002
J39.2 Other diseases of pharynx
0.002 0.997 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.003 0.997 0.000
H72.0 Central perforation of tympanic membrane
0.002 0.997 0.000
K51.2 Ulcerative (chronic) proctitis
0.003 0.997 0.000
Z43.8 Attention to other artificial openings
0.002 0.997 0.000
M65.2 Calcific tendinitis
0.000 0.997 0.002
M65.1 Other infective (teno)synovitis
0.000 0.997 0.002
M65.0 Abscess of tendon sheath
0.000 0.997 0.002
Q51.3 Bicornate uterus
0.003 0.997 0.000
H74.0 Tympanosclerosis
0.002 0.997 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.997 0.002
I24.1 Dressler's syndrome
0.000 0.997 0.002
C15.9 Oesophagus, unspecified
0.000 0.997 0.002
J32.2 Chronic ethmoidal sinusitis
0.002 0.997 0.000
J34.2 Deviated nasal septum
0.003 0.997 0.000
H69.0 Patulous Eustachian tube
0.002 0.998 0.000
M66.0 Rupture of popliteal cyst
0.000 0.998 0.002
N35.8 Other urethral stricture
0.002 0.998 0.000
H67.8 Otitis media in other diseases classified elsewhere
0.002 0.998 0.000
H67.1 Otitis media in viral diseases classified elsewhere
0.002 0.998 0.000
H67.0 Otitis media in bacterial diseases classified elsewhere
0.002 0.998 0.000
H68.1 Obstruction of Eustachian tube
0.002 0.998 0.000
H68.0 Eustachian salpingitis
0.002 0.998 0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.002 0.998 0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.002 0.998 0.000
H65.1 Other acute nonsuppurative otitis media
0.002 0.998 0.000
H65.0 Acute serous otitis media
0.002 0.998 0.000
I10-I15 Hypertensive diseases
0.000 0.998 0.002
M66.06 Rupture of popliteal cyst-Lower leg
0.000 0.998 0.002
H73 Other disorders of tympanic membrane
0.002 0.998 0.000
Q80-Q89 Other congenital malformations
0.002 0.998 0.000
I02 Rheumatic chorea
0.000 0.998 0.002
I01 Rheumatic fever with heart involvement
0.000 0.998 0.002
I00 Rheumatic fever without mention of heart involvement
0.000 0.998 0.002
H70.8 Other mastoiditis and related conditions
0.002 0.998 0.000
H70.2 Petrositis
0.002 0.998 0.000
H70.1 Chronic mastoiditis
0.002 0.998 0.000
H70.0 Acute mastoiditis
0.002 0.998 0.000
Q51 Congenital malformations of uterus and cervix
0.002 0.998 0.000
H33.1 Retinoschisis and retinal cysts
0.002 0.998 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.998 0.002
D14.0 Middle ear, nasal cavity and accessory sinuses
0.002 0.998 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.002 0.998 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.002 0.998 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.002 0.998 0.000
Q50-Q56 Congenital malformations of genital organs
0.002 0.998 0.000
Q00-Q07 Congenital malformations of the nervous system
0.002 0.998 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.002 0.998 0.000
N35.0 Posttraumatic urethral stricture
0.002 0.998 0.000
Q87.4 Marfan's syndrome
0.002 0.998 0.000
Q89 Other congenital malformations, not elsewhere classified
0.002 0.998 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.002 0.998 0.000
C15 Malignant neoplasm of oesophagus
0.000 0.998 0.002
H65.2 Chronic serous otitis media
0.002 0.998 0.000
J32.8 Other chronic sinusitis
0.002 0.998 0.001
D35.0 Adrenal gland
0.002 0.998 0.000
H70.9 Mastoiditis, unspecified
0.002 0.998 0.000
Q98.4 Klinefelter's syndrome, unspecified
0.002 0.998 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.002 0.998 0.000
Q89.2 Congenital malformations of other endocrine glands
0.002 0.998 0.000
Z97.8 Presence of other specified devices
0.000 0.998 0.002
Q66 Congenital deformities of feet
0.002 0.998 0.000
Q83 Congenital malformations of breast
0.002 0.998 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.998 0.002
M66.5 Spontaneous rupture of unspecified tendon
0.000 0.998 0.002
M66.4 Spontaneous rupture of other tendons
0.000 0.998 0.002
M66.1 Rupture of synovium
0.000 0.998 0.002
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis
0.002 0.998 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.002 0.998 0.000
D35.9 Endocrine gland, unspecified
0.002 0.998 0.000
D35.8 Pluriglandular involvement
0.002 0.998 0.000
D35.7 Other specified endocrine glands
0.002 0.998 0.000
D35.6 Aortic body and other paraganglia
0.002 0.998 0.000
D35.5 Carotid body
0.002 0.998 0.000
D35.4 Pineal gland
0.002 0.998 0.000
D35.3 Craniopharyngeal duct
0.002 0.998 0.000
I05.8 Other mitral valve diseases
0.000 0.998 0.002
I05.1 Rheumatic mitral insufficiency
0.000 0.998 0.002
I22 Subsequent myocardial infarction
0.000 0.998 0.002
D12.8 Rectum
0.000 0.998 0.002
Q07 Other congenital malformations of nervous system
0.002 0.998 0.000
M65.09 Abscess of tendon sheath (Site unspecified)
0.000 0.998 0.002
M65.08 Abscess of tendon sheath (Other)
0.000 0.998 0.002
M65.07 Abscess of tendon sheath (Ankle and foot)
0.000 0.998 0.002
M65.06 Abscess of tendon sheath (Lower leg)
0.000 0.998 0.002
M65.05 Abscess of tendon sheath (Pelvic region and thigh)
0.000 0.998 0.002
M65.04 Abscess of tendon sheath (Hand)
0.000 0.998 0.002
M65.03 Abscess of tendon sheath (Forearm)
0.000 0.998 0.002
M65.02 Abscess of tendon sheath (Upper arm)
0.000 0.998 0.002
M65.01 Abscess of tendon sheath (Shoulder region)
0.000 0.998 0.002
M65.00 Abscess of tendon sheath (Multiple sites)
0.000 0.998 0.002
M65.19 Other infective (teno)synovitis (Site unspecified)
0.000 0.998 0.002
M65.18 Other infective (teno)synovitis (Other)
0.000 0.998 0.002
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.000 0.998 0.002
M65.16 Other infective (teno)synovitis (Lower leg)
0.000 0.998 0.002
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.000 0.998 0.002
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.998 0.002
M65.13 Other infective (teno)synovitis (Forearm)
0.000 0.998 0.002
M65.12 Other infective (teno)synovitis (Upper arm)
0.000 0.998 0.002
M65.11 Other infective (teno)synovitis (Shoulder region)
0.000 0.998 0.002
M65.10 Other infective (teno)synovitis (Multiple sites)
0.000 0.998 0.002
M65.29 Calcific tendinitis (Site unspecified)
0.000 0.998 0.002
M65.28 Calcific tendinitis (Other)
0.000 0.998 0.002
M65.27 Calcific tendinitis (Ankle and foot)
0.000 0.998 0.002
M65.26 Calcific tendinitis (Lower leg)
0.000 0.998 0.002
M65.25 Calcific tendinitis (Pelvic region and thigh)
0.000 0.998 0.002
M65.24 Calcific tendinitis (Hand)
0.000 0.998 0.002
M65.23 Calcific tendinitis (Forearm)
0.000 0.998 0.002
M65.22 Calcific tendinitis (Upper arm)
0.000 0.998 0.002
M65.21 Calcific tendinitis (Shoulder region)
0.000 0.998 0.002
M65.20 Calcific tendinitis (Multiple sites)
0.000 0.998 0.002
I05.0 Mitral stenosis
0.000 0.998 0.002
M66.2 Spontaneous rupture of extensor tendons
0.000 0.998 0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.002 0.998 0.000
N20.0 Calculus of kidney
0.002 0.998 0.000
N23 Unspecified renal colic
0.002 0.998 0.000
Q05 Spina bifida
0.002 0.998 0.000
H33.5 Other retinal detachments
0.002 0.998 0.000
H69.8 Other specified disorders of Eustachian tube
0.002 0.998 0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere
0.000 0.998 0.002
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere
0.000 0.998 0.002
Q38.7 Pharyngeal pouch
0.002 0.998 0.000
Q66.8 Other congenital deformities of feet
0.002 0.998 0.000
Q83.8 Other congenital malformations of breast
0.002 0.998 0.000
C09.9 Tonsil, unspecified
0.002 0.998 0.000
Q66.3 Other congenital varus deformities of feet
0.002 0.998 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.002 0.998 0.000
M66.09 Rupture of popliteal cyst-Site unspec
0.000 0.998 0.002
M66.08 Rupture of popliteal cyst-Other
0.000 0.998 0.002
M66.07 Rupture of popliteal cyst-Ankle/foot
0.000 0.998 0.002
M66.05 Rupture of popliteal cyst-Pelvic/thigh
0.000 0.998 0.002
M66.04 Rupture of popliteal cyst-Hand
0.000 0.998 0.002
M66.03 Rupture of popliteal cyst-Forearm
0.000 0.998 0.002
M66.02 Rupture of popliteal cyst-Upper arm
0.000 0.998 0.002
M66.01 Rupture of popliteal cyst-Shldr region
0.000 0.998 0.002
M66.00 Rupture of popliteal cyst-Mult sites
0.000 0.998 0.002
Q07.0 Arnold-Chiari syndrome
0.002 0.998 0.000
S30.0 Contusion of lower back and pelvis
0.002 0.998 0.000
H26 Other cataract
0.000 0.998 0.002
Q38 Other congenital malformations of tongue, mouth and pharynx
0.002 0.998 0.000
M66.3 Spontaneous rupture of flexor tendons
0.000 0.998 0.002
S30.2 Contusion of external genital organs
0.002 0.998 0.000
H26.0 Infantile, juvenile and presenile cataract
0.000 0.998 0.002
H40.1 Primary open-angle glaucoma
0.002 0.998 0.000
H25-H28 Disorders of lens
0.000 0.998 0.002
Q05.9 Spina bifida, unspecified
0.002 0.998 0.000
I13 Hypertensive heart and renal disease
0.000 0.998 0.002
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.002 0.998 0.000
Q84 Other congenital malformations of integument
0.002 0.998 0.000
Q81 Epidermolysis bullosa
0.002 0.998 0.000
Q80 Congenital ichthyosis
0.002 0.998 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.002 0.998 0.000
H73.1 Chronic myringitis
0.002 0.998 0.000
H73.0 Acute myringitis
0.002 0.998 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.998 0.002
I01.8 Other acute rheumatic heart disease
0.000 0.998 0.002
I01.2 Acute rheumatic myocarditis
0.000 0.998 0.002
I01.1 Acute rheumatic endocarditis
0.000 0.998 0.002
I01.0 Acute rheumatic pericarditis
0.000 0.998 0.002
I02.9 Rheumatic chorea without heart involvement
0.000 0.998 0.002
I02.0 Rheumatic chorea with heart involvement
0.000 0.998 0.002
Z95.4 Presence of other heart-valve replacement
0.000 0.998 0.002
Q53 Undescended testicle
0.002 0.998 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.002 0.998 0.000
H26.8 Other specified cataract
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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