TreeWAS – Variant ID: rs12356674

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
Z90 Acquired absence of organs, not elsewhere classified	1.000	0.000	0.000
Z86 Personal history of certain other diseases	1.000	0.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E66 Obesity	1.000	0.000	0.000
I10-I15 Hypertensive diseases	1.000	0.000	0.000
J90-J94 Other diseases of pleura	1.000	0.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000	0.000
E66.8 Other obesity	1.000	0.000	0.000
E65-E68 Obesity and other hyperalimentation	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	1.000	0.000	0.000
D32 Benign neoplasm of meninges	0.999	0.001	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001	0.000
D32.0 Cerebral meninges	0.999	0.001	0.000
Z80 Family history of malignant neoplasm	0.999	0.001	0.000
Z90.7 Acquired absence of genital organ(s)	0.999	0.001	0.000
D10-D36 Benign neoplasms	0.999	0.001	0.000
Z86.7 Personal history of diseases of the circulatory system	0.998	0.002	0.000
M54.5 Low back pain	0.998	0.002	0.000
E66.9 Obesity, unspecified	0.998	0.002	0.000
I12 Hypertensive renal disease	0.997	0.003	0.000
J92 Pleural plaque	0.997	0.003	0.000
Z90.2 Acquired absence of lung [part of]	0.997	0.003	0.000
M54 Dorsalgia	0.996	0.004	0.000
Z86.0 Personal history of other neoplasms	0.996	0.004	0.000
Z80.3 Family history of malignant neoplasm of breast	0.996	0.004	0.000
Z86.4 Personal history of psychoactive substance abuse	0.995	0.005	0.000
J40-J47 Chronic lower respiratory diseases	0.995	0.005	0.000
J91 Pleural effusion in conditions classified elsewhere	0.994	0.006	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.993	0.007	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.993	0.007	0.000
M50-M54 Other dorsopathies	0.993	0.007	0.000
Z86.6 Personal history of diseases of the nervous system and sense organs	0.989	0.011	0.000
I12.0 Hypertensive renal disease with renal failure	0.989	0.011	0.000
Chapter IX Diseases of the circulatory system	0.988	0.012	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.987	0.013	0.000
J92.0 Pleural plaque with presence of asbestos	0.987	0.013	0.000
Z90.4 Acquired absence of other parts of digestive tract	0.987	0.013	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.985	0.015	0.000
M54.56 Low back pain (Lumbar region)	0.984	0.016	0.000
D35.1 Parathyroid gland	0.984	0.016	0.000
Z90.3 Acquired absence of part of stomach	0.984	0.016	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.983	0.017	0.000
J45 Asthma	0.983	0.017	0.000
Z88.2 Personal history of allergy to sulphonamides	0.983	0.017	0.000
Chapter VII Diseases of the eye and adnexa	0.982	0.018	0.000
Z98 Other postsurgical states	0.982	0.018	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.982	0.018	0.000
M54.59 Low back pain (Site unspecified)	0.981	0.019	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.981	0.019	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.980	0.020	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.980	0.020	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.980	0.020	0.000
J45.9 Asthma, unspecified	0.979	0.021	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.979	0.021	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.979	0.021	0.000
C43 Malignant melanoma of skin	0.978	0.022	0.000
Z72.0 Tobacco use	0.978	0.022	0.000
Z72 Problems related to lifestyle	0.977	0.023	0.000
H10-H13 Disorders of conjunctiva	0.976	0.024	0.000
M51 Other intervertebral disk disorders	0.975	0.025	0.000
H11 Other disorders of conjunctiva	0.972	0.028	0.000
J60-J70 Lung diseases due to external agents	0.971	0.029	0.000
J46 Status asthmaticus	0.969	0.031	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.967	0.033	0.000
H18 Other disorders of cornea	0.964	0.036	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.963	0.037	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.961	0.039	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.959	0.041	0.000
D32.9 Meninges, unspecified	0.958	0.042	0.000
M51.2 Other specified intervertebral disk displacement	0.957	0.043	0.000
J93 Pneumothorax	0.953	0.047	0.000
Z98.1 Arthrodesis status	0.953	0.047	0.000
Z57 Occupational exposure to risk-factors	0.948	0.052	0.000
D37.1 Stomach	0.947	0.053	0.000
J92.9 Pleural plaque without asbestos	0.944	0.056	0.000
I12.9 Hypertensive renal disease without renal failure	0.936	0.064	0.000
J93.9 Pneumothorax, unspecified	0.935	0.065	0.000
E20-E35 Disorders of other endocrine glands	0.931	0.069	0.000
Z98.8 Other specified postsurgical states	0.930	0.070	0.000
Z94 Transplanted organ and tissue status	0.928	0.072	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.922	0.078	0.000
I15 Secondary hypertension	0.907	0.093	0.000
Z99.2 Dependence on renal dialysis	0.907	0.093	0.000
J95-J99 Other diseases of the respiratory system	0.903	0.097	0.000
D00-D09 In situ neoplasms	0.903	0.097	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.903	0.097	0.000
H17 Corneal scars and opacities	0.902	0.098	0.000
D29 Benign neoplasm of male genital organs	0.901	0.099	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.900	0.100	0.000
Z75 Problems related to medical facilities and other health care	0.900	0.100	0.000
E50-E64 Other nutritional deficiencies	0.899	0.101	0.000
H11.0 Pterygium	0.897	0.103	0.000
Z94.7 Corneal transplant status	0.896	0.104	0.000
H11.8 Other specified disorders of conjunctiva	0.896	0.104	0.000
Z57.2 Occupational exposure to dust	0.896	0.104	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.895	0.105	0.000
D12.8 Rectum	0.893	0.107	0.000
D37.4 Colon	0.893	0.107	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.892	0.108	0.000
M54.8 Other dorsalgia	0.888	0.112	0.000
Chapter XXII Codes for special purposes	0.888	0.112	0.000
C64-C68 Malignant neoplasms of urinary tract	0.887	0.113	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.887	0.113	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.886	0.114	0.000
H18.9 Disorder of cornea, unspecified	0.879	0.121	0.000
H11.9 Disorder of conjunctiva, unspecified	0.878	0.122	0.000
M54.57 Low back pain (Lumbosacral region)	0.876	0.124	0.000
M60-M63 Disorders of muscles	0.873	0.127	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.869	0.131	0.000
J98 Other respiratory disorders	0.867	0.133	0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.866	0.134	0.000
D31 Benign neoplasm of eye and adnexa	0.864	0.136	0.000
Chapter VI Diseases of the nervous system	0.863	0.137	0.000
D29.1 Prostate	0.859	0.141	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.859	0.141	0.000
Z74 Problems related to care-provider dependency	0.858	0.142	0.000
H18.6 Keratoconus	0.857	0.143	0.000
D12.6 Colon, unspecified	0.855	0.145	0.000
G90-G99 Other disorders of the nervous system	0.853	0.147	0.000
Z94.1 Heart transplant status	0.853	0.147	0.000
I60-I69 Cerebrovascular diseases	0.852	0.148	0.000
D26 Other benign neoplasms of uterus	0.850	0.150	0.000
H17.9 Corneal scar and opacity, unspecified	0.850	0.150	0.000
M54.4 Lumbago with sciatica	0.846	0.154	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.845	0.155	0.000
D27 Benign neoplasm of ovary	0.843	0.157	0.000
E61 Deficiency of other nutrient elements	0.842	0.158	0.000
H11.1 Conjunctival degenerations and deposits	0.841	0.159	0.000
H18.2 Other corneal oedema	0.840	0.160	0.000
D44.3 Pituitary gland	0.835	0.165	0.000
C65 Malignant neoplasm of renal pelvis	0.834	0.166	0.000
H16 Keratitis	0.834	0.166	0.000
D04 Carcinoma in situ of skin	0.833	0.167	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.833	0.167	0.000
J42 Unspecified chronic bronchitis	0.832	0.168	0.000
D37.3 Appendix	0.829	0.171	0.000
C51-C58 Malignant neoplasms of female genital organs	0.827	0.173	0.000
D04.3 Skin of other and unspecified parts of face	0.826	0.174	0.000
Z57.3 Occupational exposure to other air contaminants	0.825	0.175	0.000
D32.1 Spinal meninges	0.825	0.175	0.000
C43.5 Malignant melanoma of trunk	0.822	0.178	0.000
Z60 Problems related to social environment	0.822	0.178	0.000
D05 Carcinoma in situ of breast	0.821	0.179	0.000
M54.86 Other dorsalgia (Lumbar region)	0.819	0.181	0.000
I11 Hypertensive heart disease	0.816	0.184	0.000
M54.54 Low back pain-Thoracic	0.812	0.188	0.000
D44.1 Adrenal gland	0.812	0.188	0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.812	0.188	0.000
M62 Other disorders of muscle	0.811	0.189	0.000
H18.1 Bullous keratopathy	0.811	0.189	0.000
E23 Hypofunction and other disorders of pituitary gland	0.809	0.191	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.809	0.191	0.000
D26.1 Corpus uteri	0.809	0.191	0.000
D44.4 Craniopharyngeal duct	0.809	0.191	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.807	0.193	0.000
E61.1 Iron deficiency	0.807	0.193	0.000
Z97 Presence of other devices	0.807	0.193	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.806	0.194	0.000
E28 Ovarian dysfunction	0.804	0.196	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.804	0.196	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.802	0.198	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.801	0.199	0.000
C56 Malignant neoplasm of ovary	0.800	0.200	0.000
E65 Localised adiposity	0.800	0.200	0.000
M51.4 Schmorl's nodes	0.799	0.201	0.000
D44.7 Aortic body and other paraganglia	0.799	0.201	0.000
J98.1 Pulmonary collapse	0.799	0.201	0.000
M54.9 Dorsalgia, unspecified	0.798	0.202	0.000
M80-M85 Disorders of bone density and structure	0.796	0.204	0.000
I62 Other nontraumatic intracranial haemorrhage	0.792	0.208	0.000
D48.1 Connective and other soft tissue	0.791	0.209	0.000
J98.8 Other specified respiratory disorders	0.791	0.209	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.790	0.210	0.000
Z58 Problems related to physical environment	0.789	0.211	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.788	0.212	0.000
E21.3 Hyperparathyroidism, unspecified	0.787	0.213	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.787	0.213	0.000
I15.1 Hypertension secondary to other renal disorders	0.785	0.215	0.000
D37.7 Other digestive organs	0.783	0.217	0.000
G40-G47 Episodic and paroxysmal disorders	0.783	0.217	0.000
J94 Other pleural conditions	0.782	0.218	0.000
M51.8 Other specified intervertebral disk disorders	0.782	0.218	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.782	0.218	0.000
D30 Benign neoplasm of urinary organs	0.782	0.218	0.000
D48.0 Bone and articular cartilage	0.776	0.224	0.000
I67 Other cerebrovascular diseases	0.775	0.225	0.000
D31.0 Conjunctiva	0.775	0.225	0.000
Z80.6 Family history of leukaemia	0.775	0.225	0.000
D12.5 Sigmoid colon	0.774	0.226	0.000
G97.8 Other postprocedural disorders of nervous system	0.774	0.226	0.000
H18.8 Other specified disorders of cornea	0.773	0.227	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.771	0.229	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.771	0.229	0.000
Z74.1 Need for assistance with personal care	0.770	0.230	0.000
D33.2 Brain, unspecified	0.769	0.231	0.000
I15.8 Other secondary hypertension	0.769	0.231	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.765	0.235	0.000
H55-H59 Other disorders of eye and adnexa	0.765	0.235	0.000
D37.2 Small intestine	0.763	0.237	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.762	0.238	0.000
E66.0 Obesity due to excess calories	0.758	0.242	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.757	0.243	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.755	0.245	0.000
H11.2 Conjunctival scars	0.752	0.248	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.751	0.249	0.000
Z60.9 Problem related to social environment, unspecified	0.750	0.250	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.750	0.250	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.748	0.252	0.000
J80 Adult respiratory distress syndrome	0.748	0.252	0.000
M62.8 Other specified disorders of muscle	0.743	0.257	0.000
G91 Hydrocephalus	0.742	0.258	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.740	0.260	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.739	0.260	0.000
M80 Osteoporosis with pathological fracture	0.739	0.261	0.000
H18.5 Hereditary corneal dystrophies	0.739	0.261	0.000
Z99.0 Dependence on aspirator	0.739	0.261	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.738	0.262	0.000
Z88.5 Personal history of allergy to narcotic agent	0.737	0.263	0.000
H21 Other disorders of iris and ciliary body	0.736	0.264	0.000
E63 Other nutritional deficiencies	0.736	0.264	0.000
J44 Other chronic obstructive pulmonary disease	0.735	0.265	0.000
J70 Respiratory conditions due to other external agents	0.734	0.266	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.733	0.267	0.000
I67.8 Other specified cerebrovascular diseases	0.732	0.268	0.000
H55 Nystagmus and other irregular eye movements	0.730	0.270	0.000
I00-I02 Acute rheumatic fever	0.729	0.271	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.727	0.273	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.727	0.273	0.000
H18.0 Corneal pigmentations and deposits	0.727	0.273	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.726	0.274	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.725	0.275	0.000
M54.1 Radiculopathy	0.724	0.276	0.000
E29 Testicular dysfunction	0.722	0.278	0.000
D37.9 Digestive organ, unspecified	0.722	0.278	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.722	0.278	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.721	0.279	0.000
J93.0 Spontaneous tension pneumothorax	0.721	0.279	0.000
G93 Other disorders of brain	0.719	0.281	0.000
D44.9 Endocrine gland, unspecified	0.718	0.282	0.000
Z88.0 Personal history of allergy to penicillin	0.718	0.282	0.000
D03 Melanoma in situ	0.718	0.282	0.000
E23.7 Disorder of pituitary gland, unspecified	0.717	0.283	0.000
E66.1 Drug-induced obesity	0.717	0.283	0.000
I13 Hypertensive heart and renal disease	0.717	0.283	0.000
U51 Admission status on psychiatric patients	0.717	0.283	0.000
E67 Other hyperalimentation	0.717	0.283	0.000
E68 Sequelae of hyperalimentation	0.717	0.283	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.716	0.284	0.000
D19 Benign neoplasm of mesothelial tissue	0.716	0.284	0.000
M54.53 Low back pain-Cervicothoracic	0.716	0.284	0.000
M54.52 Low back pain-Cervical	0.716	0.284	0.000
M54.51 Low back pain-Occipit-atl-axl	0.716	0.284	0.000
M54.0 Panniculitis affecting regions of neck and back	0.714	0.286	0.000
J41 Simple and mucopurulent chronic bronchitis	0.713	0.287	0.000
Chapter V Mental and behavioural disorders	0.712	0.288	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.712	0.288	0.000
G95 Other diseases of spinal cord	0.711	0.289	0.000
Z82.2 Family history of deafness and hearing loss	0.711	0.289	0.000
Z70 Counselling related to sexual attitude, behaviour and orientation	0.710	0.290	0.000
E23.0 Hypopituitarism	0.709	0.291	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.707	0.293	0.000
D35.9 Endocrine gland, unspecified	0.706	0.293	0.000
D35.8 Pluriglandular involvement	0.706	0.293	0.000
D35.7 Other specified endocrine glands	0.706	0.293	0.000
D35.6 Aortic body and other paraganglia	0.706	0.293	0.000
D35.5 Carotid body	0.706	0.293	0.000
D35.4 Pineal gland	0.706	0.293	0.000
D35.3 Craniopharyngeal duct	0.706	0.293	0.000
D44.6 Carotid body	0.706	0.294	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.705	0.295	0.000
G93.9 Disorder of brain, unspecified	0.704	0.296	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.704	0.296	0.000
D44.8 Pluriglandular involvement	0.703	0.296	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.703	0.297	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.702	0.298	0.000
C43.8 Overlapping malignant melanoma of skin	0.701	0.298	0.000
C43.0 Malignant melanoma of lip	0.701	0.298	0.000
Z72.6 Gambling and betting	0.700	0.300	0.000
Z72.5 High-risk sexual behaviour	0.700	0.300	0.000
Z72.3 Lack of physical exercise	0.700	0.300	0.000
E21.2 Other hyperparathyroidism	0.700	0.300	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.699	0.301	0.000
M54.6 Pain in thoracic spine	0.698	0.301	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.697	0.303	0.000
Z97.4 Presence of external hearing-aid	0.697	0.303	0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.696	0.304	0.000
J66 Airway disease due to specific organic dust	0.696	0.304	0.000
J63 Pneumoconiosis due to other inorganic dusts	0.696	0.304	0.000
J62 Pneumoconiosis due to dust containing silica	0.696	0.304	0.000
J65 Pneumoconiosis associated with tuberculosis	0.696	0.304	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.696	0.304	0.000
E26 Hyperaldosteronism	0.696	0.304	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.696	0.304	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.695	0.305	0.000
H15 Disorders of sclera	0.694	0.306	0.000
G47 Sleep disorders	0.694	0.306	0.000
Z65 Problems related to other psychosocial circumstances	0.693	0.307	0.000
Z62 Other problems related to upbringing	0.693	0.307	0.000
Z55 Problems related to education and literacy	0.693	0.307	0.000
H18.7 Other corneal deformities	0.691	0.308	0.000
H18.3 Changes in corneal membranes	0.691	0.308	0.000
D30.3 Bladder	0.691	0.309	0.000
D44.5 Pineal gland	0.690	0.310	0.000
D44.2 Parathyroid gland	0.690	0.310	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.690	0.310	0.000
M54.16 Radiculopathy (Lumbar region)	0.690	0.310	0.000
Z82.1 Family history of blindness and visual loss	0.688	0.312	0.000
M51.3 Other specified intervertebral disk degeneration	0.688	0.312	0.000
D33.0 Brain, supratentorial	0.688	0.312	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.688	0.312	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.686	0.314	0.000
J00-J06 Acute upper respiratory infections	0.686	0.314	0.000
G90 Disorders of autonomic nervous system	0.685	0.315	0.000
C43.4 Malignant melanoma of scalp and neck	0.685	0.315	0.000
G91.1 Obstructive hydrocephalus	0.684	0.316	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.683	0.317	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.682	0.317	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.682	0.318	0.000
Z94.2 Lung transplant status	0.682	0.318	0.000
E51 Thiamine deficiency	0.681	0.319	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.680	0.320	0.000
H13.3 Ocular pemphigoid	0.680	0.320	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.680	0.320	0.000
Z57.7 Occupational exposure to vibration	0.680	0.320	0.000
Z57.6 Occupational exposure to extreme temperature	0.680	0.320	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.680	0.320	0.000
Z57.1 Occupational exposure to radiation	0.680	0.320	0.000
Z57.0 Occupational exposure to noise	0.680	0.320	0.000
M54.84 Other dorsalgia (Thoracic region)	0.679	0.321	0.000
D37.0 Lip, oral cavity and pharynx	0.679	0.321	0.000
J47 Bronchiectasis	0.677	0.323	0.000
U80 Agent resistant to penicillin and related antibiotics	0.677	0.323	0.000
J45.8 Mixed asthma	0.676	0.324	0.000
I67.1 Cerebral aneurysm, nonruptured	0.676	0.324	0.000
Z75.5 Holiday relief care	0.675	0.325	0.000
D11 Benign neoplasm of major salivary glands	0.675	0.325	0.000
M00-M03 Infectious arthropathies	0.674	0.326	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.674	0.326	0.000
E34 Other endocrine disorders	0.674	0.326	0.000
E20 Hypoparathyroidism	0.673	0.326	0.000
Z99.8 Dependence on other enabling machines and devices	0.673	0.327	0.000
J98.9 Respiratory disorder, unspecified	0.673	0.327	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.671	0.329	0.000
Z57.8 Occupational exposure to other risk-factors	0.671	0.329	0.000
J60 Coalworker's pneumoconiosis	0.671	0.329	0.000
J98.2 Interstitial emphysema	0.671	0.329	0.000
D33.4 Spinal cord	0.670	0.330	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.670	0.330	0.000
E28.3 Primary ovarian failure	0.670	0.330	0.000
I67.2 Cerebral atherosclerosis	0.669	0.331	0.000
E31 Polyglandular dysfunction	0.668	0.332	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.667	0.333	0.000
E32 Diseases of thymus	0.667	0.333	0.000
E30 Disorders of puberty, not elsewhere classified	0.667	0.333	0.000
E25 Adrenogenital disorders	0.667	0.333	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.666	0.334	0.000
Z61 Problems related to negative life events in childhood	0.666	0.334	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.665	0.335	0.000
Z94.9 Transplanted organ and tissue status, unspecified	0.665	0.335	0.000
Z94.6 Bone transplant status	0.665	0.335	0.000
Z94.5 Skin transplant status	0.665	0.335	0.000
Z94.3 Heart and lungs transplant status	0.665	0.335	0.000
I15.0 Renovascular hypertension	0.665	0.335	0.000
D29.4 Scrotum	0.665	0.335	0.000
Z72.9 Problem related to lifestyle, unspecified	0.664	0.335	0.000
Z64 Problems related to certain psychosocial circumstances	0.664	0.336	0.000
Z81 Family history of mental and behavioural disorders	0.663	0.337	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.661	0.339	0.000
Z99.4 Dependence on artificial heart	0.661	0.339	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.660	0.340	0.000
C66 Malignant neoplasm of ureter	0.659	0.341	0.000
G43 Migraine	0.659	0.341	0.000
J64 Unspecified pneumoconiosis	0.658	0.342	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.658	0.342	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.658	0.342	0.000
D44.0 Thyroid gland	0.658	0.342	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.658	0.342	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.657	0.343	0.000
M65-M68 Disorders of synovium and tendon	0.657	0.343	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.657	0.343	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.656	0.344	0.000
Z58.7 Exposure to tobacco smoke	0.655	0.345	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.652	0.347	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.652	0.348	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.652	0.348	0.000
I15.2 Hypertension secondary to endocrine disorders	0.650	0.350	0.000
E28.2 Polycystic ovarian syndrome	0.650	0.350	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.650	0.350	0.000
Z73 Problems related to life-management difficulty	0.650	0.350	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.649	0.351	0.000
J96 Respiratory failure, not elsewhere classified	0.648	0.352	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.648	0.352	0.000
H17.1 Other central corneal opacity	0.647	0.353	0.000
H17.0 Adherent leukoma	0.647	0.353	0.000
D29.9 Male genital organ, unspecified	0.646	0.354	0.000
D29.7 Other male genital organs	0.646	0.354	0.000
D29.3 Epididymis	0.646	0.354	0.000
D29.2 Testis	0.646	0.354	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.645	0.355	0.000
Z75.0 Medical services not available in home	0.645	0.355	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.645	0.355	0.000
E50 Vitamin A deficiency	0.645	0.355	0.000
E60 Dietary zinc deficiency	0.645	0.355	0.000
E59 Dietary selenium deficiency	0.645	0.355	0.000
E54 Ascorbic acid deficiency	0.645	0.355	0.000
E52 Niacin deficiency [pellagra]	0.645	0.355	0.000
D48.4 Peritoneum	0.644	0.356	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.643	0.357	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.643	0.357	0.000
G62 Other polyneuropathies	0.642	0.358	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.642	0.358	0.000
G63.2 Diabetic polyneuropathy	0.641	0.359	0.000
J45.1 Nonallergic asthma	0.641	0.359	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.640	0.360	0.000
E21.0 Primary hyperparathyroidism	0.639	0.361	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.639	0.361	0.000
Z60.8 Other problems related to social environment	0.637	0.363	0.000
H16.8 Other keratitis	0.637	0.363	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.637	0.363	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.637	0.363	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.637	0.363	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.637	0.363	0.000
M54.82 Other dorsalgia (Cervical region)	0.637	0.363	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.637	0.363	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.637	0.363	0.000
Z93 Artificial opening status	0.637	0.363	0.000
D48.3 Retroperitoneum	0.636	0.364	0.000
E21.4 Other specified disorders of parathyroid gland	0.635	0.365	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.635	0.365	0.000
M53 Other dorsopathies, not elsewhere classified	0.633	0.366	0.000
G95.9 Disease of spinal cord, unspecified	0.633	0.367	0.000
C54 Malignant neoplasm of corpus uteri	0.632	0.368	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.632	0.368	0.000
H17.8 Other corneal scars and opacities	0.632	0.368	0.000
Z72.4 Inappropriate diet and eating habits	0.631	0.369	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.631	0.369	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.630	0.370	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.630	0.370	0.000
Z75.2 Other waiting period for investigation and treatment	0.630	0.370	0.000
I15.9 Seconday hypertension, unspecified	0.629	0.371	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.629	0.371	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.629	0.371	0.000
E40-E46 Malnutrition	0.629	0.371	0.000
E56 Other vitamin deficiencies	0.629	0.371	0.000
Z59 Problems related to housing and economic circumstances	0.627	0.373	0.000
M54.55 Low back pain (Thoracolumbar region)	0.627	0.373	0.000
E55 Vitamin D deficiency	0.627	0.373	0.000
D17 Benign lipomatous neoplasm	0.626	0.374	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.626	0.374	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.626	0.374	0.000
M61 Calcification and ossification of muscle	0.626	0.374	0.000
H16.3 Interstitial and deep keratitis	0.622	0.378	0.000
M40-M43 Deforming dorsopathies	0.622	0.378	0.000
J98.3 Compensatory emphysema	0.622	0.378	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.620	0.379	0.000
C50-C50 Malignant neoplasm of breast	0.620	0.380	0.000
D31.9 Eye, unspecified	0.620	0.380	0.000
D31.6 Orbit, unspecified	0.620	0.380	0.000
D31.5 Lachrymal gland and duct	0.620	0.380	0.000
D31.4 Ciliary body	0.620	0.380	0.000
D31.2 Retina	0.620	0.380	0.000
D31.1 Cornea	0.620	0.380	0.000
G95.0 Syringomyelia and syringobulbia	0.620	0.380	0.000
Z72.8 Other problems related to lifestyle	0.619	0.381	0.000
G60 Hereditary and idiopathic neuropathy	0.619	0.381	0.000
E63.9 Nutritional deficiency, unspecified	0.618	0.381	0.000
D38.1 Trachea, bronchus and lung	0.617	0.383	0.000
G45.0 Vertebro-basilar artery syndrome	0.617	0.383	0.000
J04 Acute laryngitis and tracheitis	0.616	0.384	0.000
Z74.3 Need for continuous supervision	0.615	0.385	0.000
E58 Dietary calcium deficiency	0.614	0.386	0.000
J94.1 Fibrothorax	0.613	0.387	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.613	0.387	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.612	0.388	0.000
G92 Toxic encephalopathy	0.612	0.388	0.000
J20-J22 Other acute lower respiratory infections	0.611	0.389	0.000
G70-G73 Diseases of myoneural junction and muscle	0.611	0.389	0.000
D26.7 Other parts of uterus	0.609	0.391	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.609	0.391	0.000
C69 Malignant neoplasm of eye and adnexa	0.608	0.392	0.000
C51 Malignant neoplasm of vulva	0.608	0.392	0.000
M62.88 Other specified disorders of muscle (Other)	0.607	0.393	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.607	0.393	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.607	0.393	0.000
M54.44 Lumbago with sciatica-Thoracic	0.607	0.393	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.607	0.393	0.000
M54.42 Lumbago with sciatica-Cervical	0.607	0.393	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.607	0.393	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.607	0.393	0.000
D33.9 Central nervous system, unspecified	0.606	0.394	0.000
D33.7 Other specified parts of central nervous system	0.606	0.394	0.000
D33.1 Brain, infratentorial	0.606	0.394	0.000
F41 Other anxiety disorders	0.606	0.394	0.000
D18 Haemangioma and lymphangioma, any site	0.604	0.394	0.001
M82 Osteoporosis in diseases classified elsewhere	0.604	0.396	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.604	0.396	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations