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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12433287
log Bayes Factor = 12.511
Chromosome 14   position 75,697,380  (GRCh37) Explore rs12433287 on Ensembl!
Variant rs12433287 is part of Cluster X0057

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
J34 Other disorders of nose and nasal sinuses
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
J34.3 Hypertrophy of nasal turbinates
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
I30-I52 Other forms of heart disease
0.992 0.008 0.000
J33 Nasal polyp
0.989 0.011 0.000
Chapter VIII Diseases of the ear and mastoid process
0.988 0.012 0.000
Chapter II Neoplasms
0.987 0.013 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.983 0.017 0.000
J33.0 Polyp of nasal cavity
0.982 0.018 0.000
C15-C26 Malignant neoplasms of digestive organs
0.975 0.025 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.975 0.025 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.971 0.029 0.000
J34.2 Deviated nasal septum
0.970 0.030 0.000
I77 Other disorders of arteries and arterioles
0.969 0.031 0.000
I45 Other conduction disorders
0.967 0.033 0.000
J20-J22 Other acute lower respiratory infections
0.964 0.036 0.000
H90-H95 Other disorders of ear
0.960 0.040 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.955 0.045 0.000
I44 Atrioventricular and left bundle-branch block
0.954 0.046 0.000
C18 Malignant neoplasm of colon
0.950 0.050 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.948 0.052 0.000
I05-I09 Chronic rheumatic heart diseases
0.943 0.057 0.000
B35-B49 Mycoses
0.943 0.057 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.940 0.060 0.000
J95-J99 Other diseases of the respiratory system
0.936 0.064 0.000
J22 Unspecified acute lower respiratory infection
0.935 0.065 0.000
Chapter XX External causes of morbidity and mortality
0.934 0.066 0.000
J38.7 Other diseases of larynx
0.933 0.067 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.929 0.071 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.928 0.072 0.000
Chapter VII Diseases of the eye and adnexa
0.923 0.077 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.923 0.077 0.000
H90 Conductive and sensorineural hearing loss
0.904 0.096 0.000
J84 Other interstitial pulmonary diseases
0.900 0.100 0.000
J81 Pulmonary oedema
0.898 0.102 0.000
I45.1 Other and unspecified right bundle-branch block
0.898 0.102 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.893 0.107 0.000
H30-H36 Disorders of choroid and retina
0.892 0.108 0.000
B25-B34 Other viral diseases
0.878 0.122 0.000
J00-J06 Acute upper respiratory infections
0.873 0.127 0.000
Q50-Q56 Congenital malformations of genital organs
0.871 0.129 0.000
I08 Multiple valve diseases
0.870 0.130 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.870 0.130 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.868 0.132 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.868 0.132 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.867 0.133 0.000
A00-A09 Intestinal infectious diseases
0.865 0.135 0.000
H65-H75 Diseases of middle ear and mastoid
0.862 0.138 0.000
S50-S59 Injuries to the elbow and forearm
0.862 0.138 0.000
C64-C68 Malignant neoplasms of urinary tract
0.859 0.141 0.000
T18 Foreign body in alimentary tract
0.857 0.143 0.000
C18.7 Sigmoid colon
0.857 0.143 0.000
C15 Malignant neoplasm of oesophagus
0.857 0.143 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.856 0.144 0.000
B37 Candidiasis
0.855 0.145 0.000
C20 Malignant neoplasm of rectum
0.854 0.146 0.000
C18.3 Hepatic flexure
0.852 0.148 0.000
I44.7 Left bundle-branch block, unspecified
0.850 0.150 0.000
I77.1 Stricture of artery
0.850 0.150 0.000
C60-C63 Malignant neoplasms of male genital organs
0.848 0.152 0.000
S70-S79 Injuries to the hip and thigh
0.846 0.154 0.000
J90-J94 Other diseases of pleura
0.845 0.155 0.000
B95-B98 Bacterial, viral and other infectious agents
0.845 0.155 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.845 0.155 0.000
E20-E35 Disorders of other endocrine glands
0.844 0.156 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.840 0.160 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.837 0.163 0.000
D00-D09 In situ neoplasms
0.832 0.168 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.831 0.169 0.000
B99-B99 Other infectious diseases
0.831 0.169 0.000
B65-B83 Helminthiases
0.827 0.173 0.000
I77.2 Rupture of artery
0.826 0.174 0.000
T66-T78 Other and unspecified effects of external causes
0.825 0.175 0.000
S80-S89 Injuries to the knee and lower leg
0.824 0.176 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.822 0.178 0.000
B37.9 Candidiasis, unspecified
0.820 0.180 0.000
B35 Dermatophytosis
0.819 0.181 0.000
H33 Retinal detachments and breaks
0.817 0.183 0.000
C51-C58 Malignant neoplasms of female genital organs
0.815 0.184 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.815 0.185 0.000
S40-S49 Injuries to the shoulder and upper arm
0.814 0.186 0.000
T87 Complications peculiar to reattachment and amputation
0.812 0.188 0.000
I34 Nonrheumatic mitral valve disorders
0.811 0.189 0.000
I45.4 Nonspecific intraventricular block
0.809 0.191 0.000
H35 Other retinal disorders
0.809 0.191 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.808 0.191 0.000
A08 Viral and other specified intestinal infections
0.808 0.192 0.000
H91 Other hearing loss
0.807 0.193 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.807 0.193 0.000
H93 Other disorders of ear, not elsewhere classified
0.807 0.193 0.000
T86 Failure and rejection of transplanted organs and tissues
0.807 0.193 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.805 0.195 0.000
I70 Atherosclerosis
0.802 0.198 0.000
H80-H83 Diseases of inner ear
0.800 0.200 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.797 0.203 0.000
J93 Pneumothorax
0.794 0.206 0.000
H90.5 Sensorineural hearing loss, unspecified
0.792 0.208 0.000
I45.3 Trifascicular block
0.791 0.209 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.790 0.210 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.789 0.211 0.000
T18.1 Foreign body in oesophagus
0.789 0.211 0.000
I44.1 Atrioventricular block, second degree
0.789 0.211 0.000
I51 Complications and ill-defined descriptions of heart disease
0.789 0.211 0.000
J32 Chronic sinusitis
0.786 0.214 0.000
Q51 Congenital malformations of uterus and cervix
0.784 0.216 0.000
C18.2 Ascending colon
0.779 0.221 0.000
V40-V49 Car occupant injured in transport accident
0.778 0.222 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.777 0.222 0.000
I44.2 Atrioventricular block, complete
0.776 0.224 0.000
C67 Malignant neoplasm of bladder
0.775 0.225 0.000
C18.6 Descending colon
0.775 0.225 0.000
C90.0 Multiple myeloma
0.774 0.226 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.774 0.226 0.000
I44.0 Atrioventricular block, first degree
0.774 0.226 0.000
C17 Malignant neoplasm of small intestine
0.772 0.228 0.000
I72 Other aneurysm
0.772 0.228 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.770 0.230 0.000
B34 Viral infection of unspecified site
0.770 0.230 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.769 0.231 0.000
H33.3 Retinal breaks without detachment
0.769 0.231 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.769 0.231 0.000
J93.1 Other spontaneous pneumothorax
0.768 0.232 0.000
C91 Lymphoid leukaemia
0.767 0.233 0.000
S10-S19 Injuries to the neck
0.765 0.235 0.000
I71 Aortic aneurysm and dissection
0.765 0.235 0.000
W50-W64 Exposure to animate mechanical forces
0.765 0.235 0.000
Chapter VI Diseases of the nervous system
0.765 0.235 0.000
J37 Chronic laryngitis and laryngotracheitis
0.764 0.236 0.000
D04 Carcinoma in situ of skin
0.764 0.236 0.000
A08.4 Viral intestinal infection, unspecified
0.764 0.236 0.000
J98 Other respiratory disorders
0.763 0.237 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.762 0.238 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.762 0.238 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.760 0.240 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.760 0.240 0.000
Y52 Agents primarily affecting the cardiovascular system
0.759 0.241 0.000
C88 Malignant immunoproliferative diseases
0.758 0.242 0.000
T00-T07 Injuries involving multiple body regions
0.757 0.243 0.000
C61 Malignant neoplasm of prostate
0.756 0.244 0.000
J33.9 Nasal polyp, unspecified
0.755 0.245 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.754 0.246 0.000
J40-J47 Chronic lower respiratory diseases
0.753 0.247 0.000
J38.2 Nodules of vocal cords
0.753 0.247 0.000
I45.2 Bifascicular block
0.753 0.247 0.000
H90.2 Conductive hearing loss, unspecified
0.751 0.249 0.000
I05 Rheumatic mitral valve diseases
0.751 0.249 0.000
T17 Foreign body in respiratory tract
0.749 0.251 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.749 0.251 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.747 0.252 0.000
I10-I15 Hypertensive diseases
0.747 0.253 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.746 0.253 0.000
S52 Fracture of forearm
0.746 0.254 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.744 0.255 0.000
I35 Nonrheumatic aortic valve disorders
0.742 0.258 0.000
C16 Malignant neoplasm of stomach
0.741 0.259 0.000
I45.6 Preexcitation syndrome
0.740 0.260 0.000
A80-A89 Viral infections of the central nervous system
0.740 0.260 0.000
M86-M90 Other osteopathies
0.740 0.260 0.000
E65-E68 Obesity and other hyperalimentation
0.740 0.260 0.000
C23 Malignant neoplasm of gallbladder
0.738 0.262 0.000
I60-I69 Cerebrovascular diseases
0.737 0.262 0.000
M80-M85 Disorders of bone density and structure
0.737 0.263 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.736 0.264 0.000
I07 Rheumatic tricuspid valve diseases
0.735 0.265 0.000
I30 Acute pericarditis
0.735 0.265 0.000
H55-H59 Other disorders of eye and adnexa
0.734 0.266 0.000
M05-M14 Inflammatory polyarthropathies
0.733 0.267 0.000
Y44 Agents primarily affecting blood constituents
0.732 0.268 0.000
E23 Hypofunction and other disorders of pituitary gland
0.732 0.268 0.000
B35.3 Tinea pedis
0.730 0.270 0.000
I42 Cardiomyopathy
0.730 0.270 0.000
J38.4 Oedema of larynx
0.730 0.270 0.000
I37 Pulmonary valve disorders
0.730 0.270 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.728 0.271 0.000
H50 Other strabismus
0.728 0.272 0.000
H35.8 Other specified retinal disorders
0.726 0.274 0.000
H43-H45 Disorders of vitreous body and globe
0.725 0.274 0.000
C56 Malignant neoplasm of ovary
0.725 0.275 0.000
Q80-Q89 Other congenital malformations
0.725 0.275 0.000
I95 Hypotension
0.725 0.275 0.000
I33 Acute and subacute endocarditis
0.724 0.276 0.000
C15.4 Middle third of oesophagus
0.723 0.276 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.722 0.278 0.000
I36 Nonrheumatic tricuspid valve disorders
0.721 0.279 0.000
Q51.3 Bicornate uterus
0.721 0.279 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.721 0.279 0.000
M45-M49 Spondylopathies
0.720 0.280 0.000
J20 Acute bronchitis
0.720 0.280 0.000
T85.2 Mechanical complication of intraocular lens
0.720 0.280 0.000
C18.9 Colon, unspecified
0.719 0.281 0.000
X50-X57 Overexertion, travel and privation
0.718 0.282 0.000
H60-H62 Diseases of external ear
0.718 0.282 0.000
J95.8 Other postprocedural respiratory disorders
0.717 0.283 0.000
I77.6 Arteritis, unspecified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
J38.5 Laryngeal spasm
0.715 0.285 0.000
B99 Other and unspecified infectious diseases
0.714 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.286 0.000
I08.0 Disorders of both mitral and aortic valves
0.714 0.286 0.000
H81 Disorders of vestibular function
0.714 0.286 0.000
J40 Bronchitis, not specified as acute or chronic
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.711 0.289 0.000
I52 Other heart disorders in diseases classified elsewhere
0.711 0.289 0.000
I48 Atrial fibrillation and flutter
0.711 0.289 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.711 0.289 0.000
I41 Myocarditis in diseases classified elsewhere
0.711 0.289 0.000
I40 Acute myocarditis
0.711 0.289 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.711 0.289 0.000
I32 Pericarditis in diseases classified elsewhere
0.711 0.289 0.000
H66 Suppurative and unspecified otitis media
0.711 0.289 0.000
Chapter XXII Codes for special purposes
0.710 0.290 0.000
C81 Hodgkin's disease
0.710 0.290 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.710 0.290 0.000
C15.5 Lower third of oesophagus
0.710 0.290 0.000
H74 Other disorders of middle ear and mastoid
0.710 0.290 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.709 0.291 0.000
J06.9 Acute upper respiratory infection, unspecified
0.709 0.291 0.000
J60-J70 Lung diseases due to external agents
0.709 0.291 0.000
C18.1 Appendix
0.709 0.291 0.000
B80 Enterobiasis
0.709 0.291 0.000
J33.1 Polypoid sinus degeneration
0.709 0.291 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.709 0.291 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.708 0.291 0.000
J03 Acute tonsillitis
0.708 0.292 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.708 0.292 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.708 0.292 0.000
B44 Aspergillosis
0.707 0.293 0.000
H31 Other disorders of choroid
0.707 0.293 0.000
B37.3 Candidiasis of vulva and vagina
0.706 0.294 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.705 0.295 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.705 0.295 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.704 0.296 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
D04.3 Skin of other and unspecified parts of face
0.703 0.297 0.000
S70 Superficial injury of hip and thigh
0.703 0.297 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.703 0.297 0.000
I49 Other cardiac arrhythmias
0.703 0.297 0.000
E22 Hyperfunction of pituitary gland
0.702 0.298 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.700 0.299 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.699 0.301 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.699 0.301 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.698 0.302 0.000
H91.9 Hearing loss, unspecified
0.698 0.302 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.698 0.302 0.000
H65 Nonsuppurative otitis media
0.697 0.303 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
H93.1 Tinnitus
0.697 0.303 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.696 0.304 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.696 0.304 0.000
H90.3 Sensorineural hearing loss, bilateral
0.696 0.304 0.000
I77.8 Other specified disorders of arteries and arterioles
0.695 0.305 0.000
I77.5 Necrosis of artery
0.695 0.305 0.000
I77.4 Coeliac artery compression syndrome
0.695 0.305 0.000
I77.3 Arterial fibromuscular dysplasia
0.695 0.305 0.000
I77.0 Arteriovenous fistula, acquired
0.695 0.305 0.000
G90-G99 Other disorders of the nervous system
0.694 0.306 0.000
T51 Toxic effect of alcohol
0.694 0.306 0.000
I45.8 Other specified conduction disorders
0.694 0.306 0.000
I45.5 Other specified heart block
0.694 0.306 0.000
I45.0 Right fascicular block
0.694 0.306 0.000
Q53 Undescended testicle
0.693 0.306 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.693 0.307 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.693 0.307 0.000
H10-H13 Disorders of conjunctiva
0.692 0.308 0.000
B34.9 Viral infection, unspecified
0.692 0.308 0.000
W20-W49 Exposure to inanimate mechanical forces
0.691 0.309 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.691 0.309 0.000
J21 Acute bronchiolitis
0.691 0.309 0.000
I44.3 Other and unspecified atrioventricular block
0.690 0.310 0.000
Y40 Systemic antibiotics
0.690 0.310 0.000
V80-V89 Other land transport accidents
0.689 0.310 0.000
B25 Cytomegaloviral disease
0.689 0.311 0.000
I74 Arterial embolism and thrombosis
0.689 0.311 0.000
T78 Adverse effects, not elsewhere classified
0.688 0.311 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.688 0.312 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.688 0.312 0.000
I44.6 Other and unspecified fascicular block
0.687 0.313 0.000
H33.4 Traction detachment of retina
0.686 0.314 0.000
S52.1 Fracture of upper end of radius
0.686 0.314 0.000
I45.9 Conduction disorder, unspecified
0.686 0.314 0.000
J38.6 Stenosis of larynx
0.685 0.315 0.000
I44.5 Left posterior fascicular block
0.684 0.316 0.000
I44.4 Left anterior fascicular block
0.684 0.316 0.000
H36 Retinal disorders in diseases classified elsewhere
0.683 0.317 0.000
M60-M63 Disorders of muscles
0.682 0.318 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.681 0.319 0.000
C18.8 Overlapping lesion of colon
0.681 0.319 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.681 0.319 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.681 0.319 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.680 0.320 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.680 0.320 0.000
C95 Leukaemia of unspecified cell type
0.680 0.320 0.000
C94 Other leukaemias of specified cell type
0.680 0.320 0.000
C93 Monocytic leukaemia
0.680 0.320 0.000
C86 Other specified types of T/NK-cell lymphoma
0.680 0.320 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.680 0.320 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.676 0.324 0.000
I09 Other rheumatic heart diseases
0.676 0.324 0.000
I06 Rheumatic aortic valve diseases
0.676 0.324 0.000
B48 Other mycoses, not elsewhere classified
0.676 0.324 0.000
B47 Mycetoma
0.676 0.324 0.000
B46 Zygomycosis
0.676 0.324 0.000
B45 Cryptococcosis
0.676 0.324 0.000
B43 Chromomycosis and phaeomycotic abscess
0.676 0.324 0.000
B42 Sporotrichosis
0.676 0.324 0.000
B41 Paracoccidioidomycosis
0.676 0.324 0.000
B40 Blastomycosis
0.676 0.324 0.000
B39 Histoplasmosis
0.676 0.324 0.000
B38 Coccidioidomycosis
0.676 0.324 0.000
B36 Other superficial mycoses
0.676 0.324 0.000
B49 Unspecified mycosis
0.676 0.324 0.000
M50-M54 Other dorsopathies
0.675 0.325 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.674 0.326 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.674 0.326 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.674 0.326 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.674 0.326 0.000
I51.8 Other ill-defined heart diseases
0.673 0.327 0.000
T18.5 Foreign body in anus and rectum
0.673 0.327 0.000
C21 Malignant neoplasm of anus and anal canal
0.673 0.327 0.000
J01 Acute sinusitis
0.672 0.328 0.000
D09 Carcinoma in situ of other and unspecified sites
0.671 0.329 0.000
E21.0 Primary hyperparathyroidism
0.671 0.329 0.000
J96 Respiratory failure, not elsewhere classified
0.671 0.329 0.000
O00-O08 Pregnancy with abortive outcome
0.671 0.329 0.000
V10-V19 Pedal cyclist injured in transport accident
0.670 0.330 0.000
Y35-Y36 Legal intervention and operations of war
0.669 0.330 0.000
Y10-Y34 Event of undetermined intent
0.669 0.330 0.000
Y00-Y09 Assault
0.669 0.330 0.000
X85-X99 Assault
0.669 0.330 0.000
X30-X39 Exposure to forces of nature
0.669 0.330 0.000
X20-X29 Contact with venomous animals and plants
0.669 0.330 0.000
X10-X19 Contact with heat and hot substances
0.669 0.330 0.000
X00-X09 Exposure to smoke, fire and flames
0.669 0.330 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.669 0.330 0.000
W75-W84 Other accidental threats to breathing
0.669 0.330 0.000
W65-W74 Accidental drowning and submersion
0.669 0.330 0.000
V98-V99 Other and unspecified transport accidents
0.669 0.330 0.000
V95-V97 Air and space transport accidents
0.669 0.330 0.000
V90-V94 Water transport accidents
0.669 0.330 0.000
V70-V79 Bus occupant injured in transport accident
0.669 0.330 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.669 0.330 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.669 0.330 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.669 0.330 0.000
V01-V09 Pedestrian injured in transport accident
0.669 0.330 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.669 0.331 0.000
C26.0 Intestinal tract, part unspecified
0.669 0.331 0.000
S51 Open wound of forearm
0.668 0.332 0.000
T58 Toxic effect of carbon monoxide
0.667 0.333 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.667 0.333 0.000
H35.9 Retinal disorder, unspecified
0.667 0.333 0.000
T19 Foreign body in genito-urinary tract
0.666 0.334 0.000
T15 Foreign body on external eye
0.666 0.334 0.000
T16 Foreign body in ear
0.666 0.334 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.665 0.334 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.665 0.334 0.000
Q35-Q37 Cleft lip and cleft palate
0.665 0.334 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.665 0.334 0.000
H49 Paralytic strabismus
0.665 0.335 0.000
C18.5 Splenic flexure
0.664 0.336 0.000
J32.9 Chronic sinusitis, unspecified
0.664 0.336 0.000
S71 Open wound of hip and thigh
0.663 0.336 0.000
C90.2 Plasmacytoma, extramedullary
0.662 0.338 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.660 0.339 0.000
Q00-Q07 Congenital malformations of the nervous system
0.660 0.340 0.000
T87.4 Infection of amputation stump
0.660 0.340 0.000
I35.9 Aortic valve disorder, unspecified
0.659 0.341 0.000
I95.1 Orthostatic hypotension
0.659 0.341 0.000
Y57 Other and unspecified drugs and medicaments
0.659 0.341 0.000
T86.1 Kidney transplant failure and rejection
0.658 0.342 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.657 0.343 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.655 0.345 0.000
O85-O92 Complications predominantly related to the puerperium
0.655 0.345 0.000
C67.9 Bladder, unspecified
0.655 0.345 0.000
H50.1 Divergent concomitant strabismus
0.654 0.346 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.654 0.346 0.000
H81.1 Benign paroxysmal vertigo
0.654 0.346 0.000
C67.6 Ureteric orifice
0.653 0.347 0.000
E23.0 Hypopituitarism
0.651 0.349 0.000
H33.1 Retinoschisis and retinal cysts
0.651 0.349 0.000
G40-G47 Episodic and paroxysmal disorders
0.651 0.349 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.650 0.349 0.000
H53-H54 Visual disturbances and blindness
0.650 0.350 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.650 0.350 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.649 0.351 0.000
I38 Endocarditis, valve unspecified
0.648 0.352 0.000
J38.3 Other diseases of vocal cords
0.648 0.352 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.648 0.352 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.648 0.352 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.648 0.352 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.648 0.352 0.000
H90.0 Conductive hearing loss, bilateral
0.648 0.352 0.000
I72.4 Aneurysm of artery of lower extremity
0.647 0.353 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.647 0.353 0.000
M84 Disorders of continuity of bone
0.646 0.354 0.000
J94 Other pleural conditions
0.646 0.354 0.000
E27 Other disorders of adrenal gland
0.646 0.354 0.000
J84.8 Other specified interstitial pulmonary diseases
0.646 0.354 0.000
J84.0 Alveolar and parietoalveolar conditions
0.646 0.354 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.645 0.355 0.000
V20-V29 Motorcycle rider injured in transport accident
0.645 0.355 0.000
G93 Other disorders of brain
0.645 0.355 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.644 0.356 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.644 0.356 0.000
W55 Bitten or struck by other mammals
0.644 0.356 0.000
S52.10 Fracture of upper end of radius (closed)
0.643 0.357 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.643 0.357 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.641 0.359 0.000
E24 Cushing's syndrome
0.641 0.359 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.641 0.359 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.640 0.360 0.000
E16 Other disorders of pancreatic internal secretion
0.640 0.360 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.639 0.361 0.000
H30 Chorioretinal inflammation
0.639 0.361 0.000
E66 Obesity
0.638 0.362 0.000
J39 Other diseases of upper respiratory tract
0.638 0.362 0.000
T87.6 Other and unspecified complications of amputation stump
0.637 0.363 0.000
C85.1 B-cell lymphoma, unspecified
0.636 0.364 0.000
Y44.2 Anticoagulants
0.635 0.365 0.000
E40-E46 Malnutrition
0.635 0.365 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.635 0.365 0.000
I34.0 Mitral (valve) insufficiency
0.634 0.366 0.000
H35.6 Retinal haemorrhage
0.634 0.366 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.633 0.367 0.000
C18.4 Transverse colon
0.632 0.367 0.000
C09 Malignant neoplasm of tonsil
0.632 0.367 0.000
I51.6 Cardiovascular disease, unspecified
0.632 0.367 0.000
M70-M79 Other soft tissue disorders
0.631 0.368 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.631 0.369 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.631 0.369 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.631 0.369 0.000
C92 Myeloid leukaemia
0.631 0.369 0.000
J47 Bronchiectasis
0.631 0.369 0.000
I31 Other diseases of pericardium
0.630 0.369 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.630 0.369 0.000
B33 Other viral diseases, not elsewhere classified
0.629 0.370 0.000
B30 Viral conjunctivitis
0.629 0.370 0.000
B27 Infectious mononucleosis
0.629 0.370 0.000
B26 Mumps
0.629 0.370 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.629 0.371 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.629 0.371 0.000
I67 Other cerebrovascular diseases
0.628 0.372 0.000
C17.2 Ileum
0.627 0.373 0.000
I42.2 Other hypertrophic cardiomyopathy
0.627 0.373 0.000
I73 Other peripheral vascular diseases
0.626 0.374 0.000
E29 Testicular dysfunction
0.626 0.374 0.000
S42 Fracture of shoulder and upper arm
0.626 0.374 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.625 0.375 0.000
Q55 Other congenital malformations of male genital organs
0.625 0.375 0.000
Q54 Hypospadias
0.625 0.375 0.000
Q52 Other congenital malformations of female genitalia
0.625 0.375 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.625 0.375 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.624 0.376 0.000
I08.9 Multiple valve disease, unspecified
0.624 0.376 0.000
I08.8 Other multiple valve diseases
0.624 0.376 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.624 0.376 0.000
I49.1 Atrial premature depolarisation
0.624 0.376 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.624 0.376 0.000
M91-M94 Chondropathies
0.624 0.376 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.623 0.377 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.623 0.377 0.000
B15-B19 Viral hepatitis
0.623 0.377 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.623 0.377 0.000
J32.4 Chronic pansinusitis
0.623 0.377 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.622 0.377 0.000
S37 Injury of urinary and pelvic organs
0.622 0.377 0.000
S36 Injury of intra-abdominal organs
0.622 0.377 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.622 0.377 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.622 0.377 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.622 0.377 0.000
S31 Open wound of abdomen, lower back and pelvis
0.622 0.377 0.000
Y59 Other and unspecified vaccines and biological substances
0.622 0.378 0.000
Y58 Bacterial vaccines
0.622 0.378 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.622 0.378 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.622 0.378 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.622 0.378 0.000
Y48 Anaesthetics and therapeutic gases
0.622 0.378 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.622 0.378 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.622 0.378 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.622 0.378 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.622 0.378 0.000
M00-M03 Infectious arthropathies
0.622 0.378 0.000
T86.0 Bone-marrow transplant rejection
0.621 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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