TreeWAS – Variant ID: rs12500355

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J44 Other chronic obstructive pulmonary disease	0.000	0.000	1.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.000	1.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.000	1.000
J43.9 Emphysema, unspecified	0.000	0.002	0.998
J43 Emphysema	0.000	0.006	0.994
J40-J47 Chronic lower respiratory diseases	0.000	0.011	0.989
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.036	0.964
J43.2 Centrilobular emphysema	0.000	0.181	0.819
J43.8 Other emphysema	0.000	0.248	0.752
J41 Simple and mucopurulent chronic bronchitis	0.000	0.281	0.719
J43.1 Panlobular emphysema	0.000	0.287	0.713
J43.0 MacLeod's syndrome	0.000	0.287	0.713
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.296	0.704
J42 Unspecified chronic bronchitis	0.000	0.305	0.695
J41.0 Simple chronic bronchitis	0.000	0.474	0.526
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.484	0.516
J41.1 Mucopurulent chronic bronchitis	0.000	0.484	0.516
J46 Status asthmaticus	0.000	0.492	0.508
J47 Bronchiectasis	0.000	0.570	0.430
J40 Bronchitis, not specified as acute or chronic	0.000	0.606	0.394
J45 Asthma	0.000	0.683	0.317
J45.1 Nonallergic asthma	0.000	0.780	0.220
J45.8 Mixed asthma	0.000	0.786	0.214
J45.9 Asthma, unspecified	0.000	0.813	0.187
J45.0 Predominantly allergic asthma	0.000	0.944	0.055
R27.0 Ataxia, unspecified	0.000	0.963	0.037
R29.6 Tendency to fall, not elsewhere classified	0.000	0.964	0.036
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.965	0.035
N86 Erosion and ectropion of cervix uteri	0.035	0.965	0.000
R27 Other lack of coordination	0.000	0.965	0.035
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.967	0.033
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.967	0.033
R26 Abnormalities of gait and mobility	0.000	0.968	0.032
R27.8 Other and unspecified lack of coordination	0.000	0.972	0.028
R26.0 Ataxic gait	0.000	0.973	0.027
R29.4 Clicking hip	0.000	0.976	0.024
R29.3 Abnormal posture	0.000	0.976	0.024
R29.0 Tetany	0.000	0.976	0.024
R29.1 Meningismus	0.000	0.977	0.023
R26.1 Paralytic gait	0.000	0.977	0.023
R29.2 Abnormal reflex	0.000	0.977	0.023
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.979	0.021
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.979	0.021
I69.3 Sequelae of cerebral infarction	0.000	0.980	0.020
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.981	0.019
I69 Sequelae of cerebrovascular disease	0.000	0.981	0.019
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.984	0.016
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.985	0.015
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.015	0.985	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.985	0.015
N61 Inflammatory disorders of breast	0.000	0.985	0.015
M54.16 Radiculopathy (Lumbar region)	0.000	0.987	0.013
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.987	0.013
R26.3 Immobility	0.000	0.987	0.012
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.990	0.010
G81.9 Hemiplegia, unspecified	0.000	0.990	0.010
Y42.5 Other oestrogens and progestogens	0.000	0.991	0.009
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.991	0.009
J38.4 Oedema of larynx	0.008	0.992	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.008	0.992	0.000
N64.1 Fat necrosis of breast	0.000	0.992	0.008
N64 Other disorders of breast	0.000	0.993	0.007
N64.4 Mastodynia	0.000	0.993	0.007
E55.9 Vitamin D deficiency, unspecified	0.000	0.993	0.007
N64.9 Disorder of breast, unspecified	0.000	0.993	0.007
N64.5 Other signs and symptoms in breast	0.000	0.993	0.007
I35.1 Aortic (valve) insufficiency	0.000	0.993	0.007
G81 Hemiplegia	0.000	0.994	0.006
K86.9 Disease of pancreas, unspecified	0.000	0.994	0.006
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.006	0.994	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.006	0.994	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.006	0.994	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.006	0.994	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.006	0.994	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.006	0.994	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.006	0.994	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.006	0.994	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.006	0.994	0.000
R25 Abnormal involuntary movements	0.000	0.994	0.006
N64.3 Galactorrhoea not associated with childbirth	0.000	0.994	0.005
N64.2 Atrophy of breast	0.000	0.994	0.005
N64.0 Fissure and fistula of nipple	0.000	0.994	0.005
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.995	0.005
G81.1 Spastic hemiplegia	0.000	0.995	0.005
G81.0 Flaccid hemiplegia	0.000	0.995	0.005
I35.9 Aortic valve disorder, unspecified	0.000	0.995	0.005
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.005	0.995	0.000
K86.8 Other specified diseases of pancreas	0.000	0.995	0.005
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.995	0.005
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.995	0.005
E55 Vitamin D deficiency	0.000	0.995	0.004
C34.1 Upper lobe, bronchus or lung	0.000	0.996	0.004
R25.0 Abnormal head movements	0.000	0.996	0.004
K86 Other diseases of pancreas	0.000	0.996	0.004
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.996	0.004
J38.1 Polyp of vocal cord and larynx	0.004	0.996	0.000
Z86.0 Personal history of other neoplasms	0.000	0.996	0.004
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.004	0.996	0.000
F17.1 Harmful use	0.000	0.996	0.004
N60-N64 Disorders of breast	0.000	0.996	0.004
J38.7 Other diseases of larynx	0.004	0.996	0.000
H33.3 Retinal breaks without detachment	0.000	0.996	0.004
S90.0 Contusion of ankle	0.004	0.996	0.000
J38.3 Other diseases of vocal cords	0.004	0.996	0.000
G82 Paraplegia and tetraplegia	0.000	0.996	0.004
E55.0 Rickets, active	0.000	0.996	0.003
N81.5 Vaginal enterocele	0.000	0.997	0.003
C56 Malignant neoplasm of ovary	0.000	0.997	0.003
K86.2 Cyst of pancreas	0.000	0.997	0.003
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.997	0.003
G82.5 Tetraplegia, unspecified	0.000	0.997	0.003
G82.4 Spastic tetraplegia	0.000	0.997	0.003
R25.3 Fasciculation	0.000	0.997	0.003
R25.1 Tremor, unspecified	0.000	0.997	0.003
G82.1 Spastic paraplegia	0.000	0.997	0.003
I35 Nonrheumatic aortic valve disorders	0.000	0.997	0.003
N64.8 Other specified disorders of breast	0.000	0.997	0.003
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.997	0.003
C22.0 Liver cell carcinoma	0.000	0.997	0.003
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.000	0.997	0.003
I51.9 Heart disease, unspecified	0.003	0.997	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.997	0.003
K29.0 Acute haemorrhagic gastritis	0.003	0.997	0.000
G82.3 Flaccid tetraplegia	0.000	0.997	0.003
G82.0 Flaccid paraplegia	0.000	0.997	0.003
H11.9 Disorder of conjunctiva, unspecified	0.000	0.997	0.003
K80.4 Calculus of bile duct with cholecystitis	0.000	0.997	0.003
C22.9 Liver, unspecified	0.000	0.997	0.003
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.003
J38.0 Paralysis of vocal cords and larynx	0.003	0.997	0.000
O16 Unspecified maternal hypertension	0.000	0.997	0.003
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.997	0.003
O81.3 Other and unspecified forceps delivery	0.003	0.997	0.000
J38.6 Stenosis of larynx	0.002	0.997	0.000
L93.0 Discoid lupus erythematosus	0.000	0.997	0.003
E50-E64 Other nutritional deficiencies	0.000	0.997	0.003
C71.9 Brain, unspecified	0.003	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.002	0.998	0.000
Z96.8 Presence of other specified functional implants	0.000	0.998	0.002
T86 Failure and rejection of transplanted organs and tissues	0.000	0.998	0.002
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.002	0.998	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.002	0.998	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.002	0.998	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.002	0.998	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.002	0.998	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.002	0.998	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.002	0.998	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.002	0.998	0.000
T86.4 Liver transplant failure and rejection	0.000	0.998	0.002
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.998	0.002
J98.9 Respiratory disorder, unspecified	0.000	0.998	0.002
M86.9 Osteomyelitis, unspecified	0.000	0.998	0.002
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
J91 Pleural effusion in conditions classified elsewhere	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
O15 Eclampsia	0.000	0.998	0.002
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.998	0.002
I05.0 Mitral stenosis	0.000	0.998	0.002
M15.8 Other polyarthrosis	0.002	0.998	0.000
O43.1 Malformation of placenta	0.000	0.998	0.002
M15.1 Heberden's nodes (with arthropathy)	0.002	0.998	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.998	0.002
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.998	0.002
E53 Deficiency of other B group vitamins	0.000	0.998	0.002
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.998	0.002
E61 Deficiency of other nutrient elements	0.000	0.998	0.002
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
E51 Thiamine deficiency	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
M15.3 Secondary multiple arthrosis	0.002	0.998	0.000
H59.0 Vitreous syndrome following cataract surgery	0.000	0.998	0.002
E61.2 Magnesium deficiency	0.000	0.998	0.002
K65.8 Other peritonitis	0.000	0.998	0.002
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
M15 Polyarthrosis	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
M80.5 Idiopathic osteoporosis with pathological fracture	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
D29.1 Prostate	0.000	0.998	0.002
J15.1 Pneumonia due to Pseudomonas	0.000	0.998	0.002
Z31.2 In vitro fertilisation	0.000	0.998	0.002
T78.0 Anaphylactic shock due to adverse food reaction	0.002	0.998	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.998	0.002
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.998	0.002
E63 Other nutritional deficiencies	0.000	0.998	0.002
E50 Vitamin A deficiency	0.000	0.998	0.002
E60 Dietary zinc deficiency	0.000	0.998	0.002
E59 Dietary selenium deficiency	0.000	0.998	0.002
E54 Ascorbic acid deficiency	0.000	0.998	0.002
E52 Niacin deficiency [pellagra]	0.000	0.998	0.002
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
J38.5 Laryngeal spasm	0.002	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.998	0.002
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.998	0.002
T86.3 Heart-lung transplant failure and rejection	0.000	0.998	0.002
T86.2 Heart transplant failure and rejection	0.000	0.998	0.002
E58 Dietary calcium deficiency	0.000	0.998	0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
I51.3 Intracardiac thrombosis, not elsewhere classified	0.002	0.998	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.002	0.998	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.998	0.002
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.998	0.002
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.998	0.002
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.998	0.002
F17.2 Dependence syndrome	0.000	0.998	0.002
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
O15.9 Eclampsia, unspecified as to time period	0.000	0.998	0.002
O15.2 Eclampsia in the puerperium	0.000	0.998	0.002
O15.1 Eclampsia in labour	0.000	0.998	0.002
O15.0 Eclampsia in pregnancy	0.000	0.998	0.002
E51.2 Wernicke's encephalopathy	0.000	0.998	0.002
O14.2 HELLP syndrome	0.000	0.998	0.002
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
D07.5 Prostate	0.000	0.998	0.002
M15.0 Primary generalised (osteo)arthrosis	0.002	0.998	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
F17.9 Unspecified mental and behavioural disorder	0.000	0.998	0.002
F17.8 Other mental and behavioural disorders	0.000	0.998	0.002
F17.7 Residual and late-onset psychotic disorder	0.000	0.998	0.002
F17.6 Amnesic syndrome	0.000	0.998	0.002
F17.5 Psychotic disorder	0.000	0.998	0.002
F17.4 Withdrawal state with delirium	0.000	0.998	0.002
F17.3 Withdrawal state	0.000	0.998	0.002
F17.0 Acute intoxication	0.000	0.998	0.002
G80 Infantile cerebral palsy	0.000	0.998	0.002
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.998	0.002
E56 Other vitamin deficiencies	0.000	0.998	0.002
M80.88 Other osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
B02.3 Zoster ocular disease	0.000	0.998	0.002
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
E53.1 Pyridoxine deficiency	0.000	0.998	0.002
E53.0 Riboflavin deficiency	0.000	0.998	0.002
E61.9 Deficiency of nutrient element, unspecified	0.000	0.998	0.002
E61.8 Deficiency of other specified nutrient elements	0.000	0.998	0.002
E61.7 Deficiency of multiple nutrient elements	0.000	0.998	0.002
E61.6 Vanadium deficiency	0.000	0.998	0.002
E61.5 Molybdenum deficiency	0.000	0.998	0.002
E61.4 Chromium deficiency	0.000	0.998	0.002
E61.3 Manganese deficiency	0.000	0.998	0.002
E61.0 Copper deficiency	0.000	0.998	0.002
O14.0 Moderate preeclampsia	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
Y42.4 Oral contraceptives	0.000	0.998	0.002
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.000	0.998	0.002
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.002	0.998	0.000
E51.9 Thiamine deficiency, unspecified	0.000	0.998	0.002
E51.8 Other manifestations of thiamine deficiency	0.000	0.998	0.002
E51.1 Beriberi	0.000	0.998	0.002
E53.9 Vitamin B deficiency, unspecified	0.000	0.998	0.002
T86.0 Bone-marrow transplant rejection	0.000	0.998	0.002
H21.0 Hyphaema	0.000	0.998	0.002
J38.2 Nodules of vocal cords	0.002	0.998	0.000
T01.2 Open wounds involving multiple regions of upper limb(s)	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.000	0.998	0.002
C71.3 Parietal lobe	0.002	0.998	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.998	0.002
K07.6 Temporomandibular joint disorders	0.002	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.998	0.002
O14.1 Severe preeclampsia	0.000	0.998	0.002
Y46.2 Hydantoin derivatives	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
M15.4 Erosive (osteo)arthrosis	0.002	0.998	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.998	0.002
C22.7 Other specified carcinomas of liver	0.000	0.998	0.002
C22.4 Other sarcomas of liver	0.000	0.998	0.002
C22.3 Angiosarcoma of liver	0.000	0.998	0.002
C22.2 Hepatoblastoma	0.000	0.998	0.002
E50.9 Vitamin A deficiency, unspecified	0.000	0.998	0.002
E50.8 Other manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.998	0.002
E50.5 Vitamin A deficiency with night blindness	0.000	0.998	0.002
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.998	0.002
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.998	0.002
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.998	0.002
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.998	0.002
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.998	0.002
E63.9 Nutritional deficiency, unspecified	0.000	0.998	0.002
E63.8 Other specified nutritional deficiencies	0.000	0.998	0.002
E63.1 Imbalance of constituents of food intake	0.000	0.998	0.002
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.998	0.002
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.998	0.002
E64.8 Sequelae of other nutritional deficiencies	0.000	0.998	0.002
E64.3 Sequelae of rickets	0.000	0.998	0.002
E64.2 Sequelae of vitamin C deficiency	0.000	0.998	0.002
E64.1 Sequelae of vitamin A deficiency	0.000	0.998	0.002
E64.0 Sequelae of protein-energy malnutrition	0.000	0.998	0.002
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
T86.1 Kidney transplant failure and rejection	0.000	0.998	0.002
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
N80.9 Endometriosis, unspecified	0.002	0.998	0.000
R22.2 Localised swelling, mass and lump, trunk	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
E61.1 Iron deficiency	0.000	0.998	0.002
K25.4 Chronic or unspecified with haemorrhage	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
G80.2 Infantile hemiplegia	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
H18.4 Corneal degeneration	0.000	0.998	0.002
M15.9 Polyarthrosis, unspecified	0.002	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.002	0.998	0.000
G80.4 Ataxic cerebral palsy	0.000	0.998	0.001
G80.3 Dyskinetic cerebral palsy	0.000	0.998	0.001
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.998	0.002
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.002	0.998	0.000
E56.9 Vitamin deficiency, unspecified	0.000	0.998	0.001
E56.8 Deficiency of other vitamins	0.000	0.998	0.001
E56.0 Deficiency of vitamin E	0.000	0.998	0.001
H20.0 Acute and subacute iridocyclitis	0.000	0.998	0.002
O43.8 Other placental disorders	0.000	0.998	0.002
S13.4 Sprain and strain of cervical spine	0.000	0.998	0.002
G80.1 Spastic diplegia	0.000	0.998	0.001
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
Y48.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.998	0.002
I35.8 Other aortic valve disorders	0.000	0.998	0.001
O69.0 Labour and delivery complicated by prolapse of cord	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
W44.0 Home	0.000	0.998	0.002
I35.0 Aortic (valve) stenosis	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
G80.8 Other infantile cerebral palsy	0.000	0.998	0.001
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.000	0.998	0.002
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.002	0.998	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.001	0.998	0.000
B02.2 Zoster with other nervous system involvement	0.000	0.998	0.002
G43.9 Migraine, unspecified	0.000	0.998	0.002
R23.4 Changes in skin texture	0.000	0.998	0.002
Y47.1 Benzodiazepines	0.000	0.998	0.001
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.998	0.002
O81.5 Delivery by combination of forceps and vacuum extractor	0.001	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.001	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.001	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
K51.8 Other ulcerative colitis	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.001	0.998	0.000
S93.4 Sprain and strain of ankle	0.001	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.998	0.000
X78.0 Home	0.000	0.998	0.001
M53 Other dorsopathies, not elsewhere classified	0.001	0.998	0.000
O43 Placental disorders	0.000	0.998	0.002
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.998	0.002
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.001
I44.2 Atrioventricular block, complete	0.000	0.998	0.002
I51.4 Myocarditis, unspecified	0.001	0.998	0.000
O81.0 Low forceps delivery	0.001	0.998	0.000
M53.96 Dorsopathy, unspecified (Lumbar region)	0.001	0.999	0.000
A63.0 Anogenital (venereal) warts	0.000	0.999	0.001
G83.8 Other specified paralytic syndromes	0.000	0.999	0.001
M53.9 Dorsopathy, unspecified	0.001	0.999	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.999	0.001
Z31.8 Other procreative management	0.000	0.999	0.001
I74 Arterial embolism and thrombosis	0.000	0.999	0.001
Y48 Anaesthetics and therapeutic gases	0.000	0.999	0.001
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.999	0.001
E56.1 Deficiency of vitamin K	0.000	0.999	0.001
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.999	0.001
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.999	0.001
Y49.2 Other and unspecified antidepressants	0.000	0.999	0.001
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.999	0.001
Y95 Nosocomial condition	0.000	0.999	0.001
Z31 Procreative management	0.000	0.999	0.001
C18.3 Hepatic flexure	0.000	0.999	0.001
H16.0 Corneal ulcer	0.000	0.999	0.001
I05.8 Other mitral valve diseases	0.000	0.999	0.001
J15.8 Other bacterial pneumonia	0.000	0.999	0.001
K07.1 Anomalies of jaw-cranial base relationship	0.001	0.999	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.999	0.001
S20.2 Contusion of thorax	0.001	0.999	0.000
Y46.4 Iminostilbenes	0.000	0.999	0.001
G83 Other paralytic syndromes	0.000	0.999	0.001
I51 Complications and ill-defined descriptions of heart disease	0.001	0.999	0.000
M43.06 Spondylolysis (Lumbar region)	0.000	0.999	0.001
G80.0 Spastic cerebral palsy	0.000	0.999	0.001
H54.4 Blindness, one eye	0.000	0.999	0.001
I74.8 Embolism and thrombosis of other arteries	0.000	0.999	0.001
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.999	0.001
O12.2 Gestational oedema with proteinuria	0.000	0.999	0.001
O12.1 Gestational proteinuria	0.000	0.999	0.001
O32.4 Maternal care for high head at term	0.000	0.999	0.001
Y52 Agents primarily affecting the cardiovascular system	0.000	0.999	0.001
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.999	0.001
M88.9 Paget's disease of bone, unspecified	0.001	0.999	0.000
N80.5 Endometriosis of intestine	0.001	0.999	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.999	0.000
Y48.4 Anaesthetic, unspecified	0.000	0.999	0.001
Y49.5 Other antipsychotics and neuroleptics	0.000	0.999	0.001
M53.2 Spinal instabilities	0.001	0.999	0.000
O32.8 Maternal care for other malpresentation of foetus	0.000	0.999	0.001
R25.2 Cramp and spasm	0.000	0.999	0.001
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.999	0.001
J98 Other respiratory disorders	0.000	0.999	0.001
C71.2 Temporal lobe	0.001	0.999	0.000
H02.3 Blepharochalasis	0.001	0.999	0.000
H16.2 Keratoconjunctivitis	0.000	0.999	0.001
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.999	0.001
S20.8 Superficial injuries of other and unspecified parts of thorax	0.001	0.999	0.000
W50.9 Unspecified place	0.001	0.999	0.000
Y46.8 Antispasticity drugs	0.000	0.999	0.001
Y46.7 Anti-Parkinsonism drugs	0.000	0.999	0.001
Y46.5 Valproic acid	0.000	0.999	0.001
Y46.3 Deoxybarbiturates	0.000	0.999	0.001
Y46.1 Oxazolidinediones	0.000	0.999	0.001
Y46.0 Succinimides	0.000	0.999	0.001
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.999	0.001
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.999	0.001
M15.99 Polyosteoarthritis, unspecified	0.001	0.999	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations