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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12589674
log Bayes Factor = 5.86884
Chromosome 14   position 54,246,353  (GRCh37) Explore rs12589674 on Ensembl!
Variant rs12589674 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
B95-B98 Bacterial, viral and other infectious agents
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.984 0.016 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.978 0.022 0.000
M20-M25 Other joint disorders
0.977 0.023 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.976 0.024 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.974 0.026 0.000
M25 Other joint disorders, not elsewhere classified
0.969 0.031 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.965 0.035 0.000
S80-S89 Injuries to the knee and lower leg
0.965 0.035 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.963 0.037 0.000
M50-M54 Other dorsopathies
0.961 0.039 0.000
Chapter VII Diseases of the eye and adnexa
0.955 0.045 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.955 0.045 0.000
M80-M85 Disorders of bone density and structure
0.952 0.048 0.000
M51 Other intervertebral disk disorders
0.949 0.051 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.948 0.052 0.000
H25-H28 Disorders of lens
0.947 0.053 0.000
S81 Open wound of lower leg
0.947 0.053 0.000
S90-S99 Injuries to the ankle and foot
0.939 0.061 0.000
M51.2 Other specified intervertebral disk displacement
0.935 0.065 0.000
S81.8 Open wound of other parts of lower leg
0.929 0.071 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.926 0.074 0.000
H26 Other cataract
0.925 0.075 0.000
H26.4 After-cataract
0.922 0.078 0.000
D69 Purpura and other haemorrhagic conditions
0.922 0.078 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.921 0.079 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.921 0.079 0.000
Chapter VI Diseases of the nervous system
0.921 0.079 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.917 0.083 0.000
T90 Sequelae of injuries of head
0.915 0.085 0.000
M25.5 Pain in joint
0.914 0.086 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.909 0.091 0.000
D69.6 Thrombocytopenia, unspecified
0.907 0.093 0.000
Q60-Q64 Congenital malformations of the urinary system
0.904 0.096 0.000
S10-S19 Injuries to the neck
0.902 0.098 0.000
M25.8 Other specified joint disorders
0.901 0.099 0.000
F30-F39 Mood [affective] disorders
0.899 0.101 0.000
D68 Other coagulation defects
0.893 0.107 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.892 0.108 0.000
M25.3 Other instability of joint
0.886 0.114 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.879 0.121 0.000
H25 Senile cataract
0.875 0.125 0.000
H43-H45 Disorders of vitreous body and globe
0.873 0.127 0.000
F99-F99 Unspecified mental disorder
0.873 0.127 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.871 0.129 0.000
M81 Osteoporosis without pathological fracture
0.868 0.132 0.000
B15-B19 Viral hepatitis
0.862 0.138 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.861 0.139 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.861 0.139 0.000
F60-F69 Disorders of adult personality and behaviour
0.860 0.140 0.000
V80-V89 Other land transport accidents
0.859 0.140 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.859 0.141 0.000
Q00-Q07 Congenital malformations of the nervous system
0.858 0.142 0.000
Chapter VIII Diseases of the ear and mastoid process
0.856 0.144 0.000
S92 Fracture of foot, except ankle
0.855 0.145 0.000
M21 Other acquired deformities of limbs
0.852 0.148 0.000
Chapter XXII Codes for special purposes
0.852 0.148 0.000
H25.0 Senile incipient cataract
0.852 0.148 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.846 0.154 0.000
M25.57 Pain in joint (Ankle and foot)
0.843 0.157 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.842 0.158 0.000
T79-T79 Certain early complications of trauma
0.842 0.158 0.000
H43 Disorders of vitreous body
0.840 0.160 0.000
G90-G99 Other disorders of the nervous system
0.840 0.160 0.000
T93 Sequelae of injuries of lower limb
0.840 0.160 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.839 0.161 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.837 0.163 0.000
M85 Other disorders of bone density and structure
0.836 0.164 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.834 0.166 0.000
M24 Other specific joint derangements
0.834 0.166 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.833 0.167 0.000
S90 Superficial injury of ankle and foot
0.832 0.168 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.831 0.169 0.000
I49 Other cardiac arrhythmias
0.828 0.172 0.000
T91 Sequelae of injuries of neck and trunk
0.828 0.172 0.000
I30-I52 Other forms of heart disease
0.827 0.173 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.826 0.174 0.000
G95 Other diseases of spinal cord
0.824 0.176 0.000
F31 Bipolar affective disorder
0.823 0.177 0.000
T90.9 Sequelae of unspecified injury of head
0.821 0.179 0.000
G70-G73 Diseases of myoneural junction and muscle
0.811 0.189 0.000
H43.8 Other disorders of vitreous body
0.810 0.190 0.000
M81.9 Osteoporosis, unspecified
0.809 0.191 0.000
Chapter X Diseases of the respiratory system
0.808 0.192 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.807 0.193 0.000
S82 Fracture of lower leg, including ankle
0.805 0.195 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.804 0.196 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.803 0.197 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.803 0.197 0.000
V10-V19 Pedal cyclist injured in transport accident
0.801 0.199 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.800 0.200 0.000
H25.9 Senile cataract, unspecified
0.799 0.201 0.000
W20-W49 Exposure to inanimate mechanical forces
0.798 0.202 0.000
Chapter IX Diseases of the circulatory system
0.798 0.202 0.000
M25.84 Other specified joint disorders (Hand)
0.796 0.204 0.000
F33 Recurrent depressive disorder
0.796 0.204 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.795 0.205 0.000
F99 Mental disorder, not otherwise specified
0.793 0.207 0.000
F05.9 Delirium, unspecified
0.793 0.207 0.000
S14 Injury of nerves and spinal cord at neck level
0.792 0.208 0.000
H55-H59 Other disorders of eye and adnexa
0.792 0.208 0.000
M60-M63 Disorders of muscles
0.790 0.210 0.000
H65-H75 Diseases of middle ear and mastoid
0.790 0.210 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.789 0.211 0.000
X60-X84 Intentional self-harm
0.789 0.211 0.000
D68.8 Other specified coagulation defects
0.789 0.211 0.000
I49.5 Sick sinus syndrome
0.788 0.212 0.000
M25.59 Pain in joint (Site unspecified)
0.787 0.213 0.000
I47 Paroxysmal tachycardia
0.786 0.214 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.786 0.214 0.000
M25.37 Other instability of joint (Ankle and foot)
0.785 0.215 0.000
I49.0 Ventricular fibrillation and flutter
0.785 0.215 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.784 0.216 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.783 0.217 0.000
J09-J18 Influenza and pneumonia
0.783 0.217 0.000
M30 Polyarteritis nodosa and related conditions
0.783 0.217 0.000
T90.4 Sequelae of injury of eye and orbit
0.782 0.218 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.781 0.219 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.781 0.219 0.000
M33 Dermatopolymyositis
0.778 0.222 0.000
D80-D89 Certain disorders involving the immune mechanism
0.777 0.223 0.000
M53 Other dorsopathies, not elsewhere classified
0.775 0.225 0.000
M00-M03 Infectious arthropathies
0.775 0.225 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.772 0.228 0.000
T40.2 Other opioids
0.770 0.229 0.000
I44 Atrioventricular and left bundle-branch block
0.769 0.231 0.000
J18 Pneumonia, organism unspecified
0.768 0.232 0.000
M34 Systemic sclerosis
0.767 0.233 0.000
M84 Disorders of continuity of bone
0.767 0.233 0.000
I49.3 Ventricular premature depolarisation
0.766 0.234 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.765 0.235 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.764 0.235 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.761 0.239 0.000
B50-B64 Protozoal diseases
0.760 0.240 0.000
I47.2 Ventricular tachycardia
0.759 0.241 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.759 0.241 0.000
Q05 Spina bifida
0.759 0.241 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.758 0.242 0.000
T42.1 Iminostilbenes
0.758 0.242 0.000
A15-A19 Tuberculosis
0.757 0.243 0.000
S81.0 Open wound of knee
0.757 0.243 0.000
T92 Sequelae of injuries of upper limb
0.757 0.243 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.756 0.244 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.755 0.245 0.000
S70-S79 Injuries to the hip and thigh
0.754 0.246 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.754 0.246 0.000
Q61 Cystic kidney disease
0.754 0.246 0.000
M91-M94 Chondropathies
0.754 0.246 0.000
S82.4 Fracture of fibula alone
0.753 0.247 0.000
I44.2 Atrioventricular block, complete
0.752 0.248 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.752 0.248 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.749 0.251 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.747 0.253 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.747 0.253 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.745 0.254 0.000
G30-G32 Other degenerative diseases of the nervous system
0.745 0.255 0.000
V20-V29 Motorcycle rider injured in transport accident
0.744 0.256 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.744 0.256 0.000
T39.1 4-Aminophenol derivatives
0.743 0.257 0.000
M86-M90 Other osteopathies
0.743 0.257 0.000
F60 Specific personality disorders
0.742 0.258 0.000
M51.8 Other specified intervertebral disk disorders
0.741 0.258 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.740 0.260 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.739 0.261 0.000
M24.0 Loose body in joint
0.737 0.263 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.737 0.263 0.000
M25.51 Pain in joint (Shoulder region)
0.736 0.264 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.735 0.265 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.733 0.267 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.732 0.268 0.000
M25.50 Pain in joint (Multiple sites)
0.730 0.270 0.000
J18.1 Lobar pneumonia, unspecified
0.730 0.270 0.000
M51.4 Schmorl's nodes
0.730 0.270 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.730 0.270 0.000
G95.9 Disease of spinal cord, unspecified
0.730 0.270 0.000
M40-M43 Deforming dorsopathies
0.729 0.271 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.729 0.271 0.000
D68.9 Coagulation defect, unspecified
0.729 0.271 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.728 0.272 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.728 0.272 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.727 0.273 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.727 0.273 0.000
M25.9 Joint disorder, unspecified
0.725 0.275 0.000
M25.0 Haemarthrosis
0.723 0.277 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.723 0.277 0.000
T00-T07 Injuries involving multiple body regions
0.721 0.278 0.000
B25-B34 Other viral diseases
0.721 0.279 0.000
S86 Injury of muscle and tendon at lower leg level
0.720 0.280 0.000
G95.2 Cord compression, unspecified
0.719 0.281 0.000
S40-S49 Injuries to the shoulder and upper arm
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
M21.1 Varus deformity, not elsewhere classified
0.716 0.283 0.000
S82.40 Fracture of fibula alone (closed)
0.716 0.284 0.000
M85.6 Other cyst of bone
0.716 0.284 0.000
B18 Chronic viral hepatitis
0.715 0.285 0.000
Y88 Sequelae of surgical and medical care as external cause
0.715 0.285 0.000
S14.1 Other and unspecified injuries of cervical spinal cord
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.713 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.713 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.713 0.286 0.000
T36 Poisoning by systemic antibiotics
0.713 0.286 0.000
S92.3 Fracture of metatarsal bone
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.288 0.000
A75-A79 Rickettsioses
0.711 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.288 0.000
A65-A69 Other spirochaetal diseases
0.711 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.288 0.000
J40-J47 Chronic lower respiratory diseases
0.711 0.289 0.000
F20 Schizophrenia
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
M25.31 Other instability of joint (Shoulder region)
0.707 0.293 0.000
D86 Sarcoidosis
0.707 0.293 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.706 0.294 0.000
J47 Bronchiectasis
0.706 0.294 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.706 0.294 0.000
F70-F79 Mental retardation
0.706 0.294 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.705 0.295 0.000
Y52 Agents primarily affecting the cardiovascular system
0.703 0.297 0.000
S12 Fracture of neck
0.702 0.298 0.000
I49.4 Other and unspecified premature depolarisation
0.702 0.298 0.000
T95 Sequelae of burns, corrosions and frostbite
0.701 0.298 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.701 0.298 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.701 0.298 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.702 0.298 0.000
M21.6 Other acquired deformities of ankle and foot
0.700 0.300 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.700 0.300 0.000
M32 Systemic lupus erythematosus
0.700 0.300 0.000
G95.8 Other specified diseases of spinal cord
0.700 0.300 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.700 0.300 0.000
Q35-Q37 Cleft lip and cleft palate
0.700 0.300 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.700 0.300 0.000
G95.1 Vascular myelopathies
0.700 0.300 0.000
T91.3 Sequelae of injury of spinal cord
0.698 0.302 0.000
I42 Cardiomyopathy
0.696 0.304 0.000
S82.5 Fracture of medial malleolus
0.696 0.304 0.000
B99-B99 Other infectious diseases
0.695 0.304 0.000
M25.2 Flail joint
0.695 0.305 0.000
M25.1 Fistula of joint
0.695 0.305 0.000
Q64 Other congenital malformations of urinary system
0.694 0.306 0.000
B65-B83 Helminthiases
0.694 0.306 0.000
H43.3 Other vitreous opacities
0.694 0.306 0.000
H90-H95 Other disorders of ear
0.694 0.306 0.000
G62 Other polyneuropathies
0.693 0.307 0.000
D66 Hereditary factor VIII deficiency
0.693 0.307 0.000
S31 Open wound of abdomen, lower back and pelvis
0.693 0.307 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.692 0.308 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.692 0.308 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.692 0.308 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.692 0.308 0.000
S88 Traumatic amputation of lower leg
0.692 0.308 0.000
S87 Crushing injury of lower leg
0.692 0.308 0.000
S85 Injury of blood vessels at lower leg level
0.692 0.308 0.000
S84 Injury of nerves at lower leg level
0.692 0.308 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.692 0.308 0.000
F33.9 Recurrent depressive disorder, unspecified
0.692 0.308 0.000
Q44.6 Cystic disease of liver
0.691 0.309 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.690 0.310 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.689 0.310 0.000
X10-X19 Contact with heat and hot substances
0.689 0.310 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.689 0.311 0.000
F00 Dementia in Alzheimer's disease
0.689 0.311 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.689 0.311 0.000
M50 Cervical disk disorders
0.689 0.311 0.000
I31 Other diseases of pericardium
0.688 0.311 0.000
H72 Perforation of tympanic membrane
0.687 0.313 0.000
Q05.9 Spina bifida, unspecified
0.687 0.313 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.686 0.313 0.000
I34 Nonrheumatic mitral valve disorders
0.686 0.314 0.000
D69.4 Other primary thrombocytopenia
0.685 0.315 0.000
Q76 Congenital malformations of spine and bony thorax
0.685 0.315 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.684 0.316 0.000
S92.0 Fracture of calcaneus
0.684 0.316 0.000
Q66 Congenital deformities of feet
0.684 0.316 0.000
F30 Manic episode
0.684 0.316 0.000
J00-J06 Acute upper respiratory infections
0.684 0.316 0.000
M83 Adult osteomalacia
0.683 0.317 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.682 0.317 0.000
B16 Acute hepatitis B
0.682 0.318 0.000
M82 Osteoporosis in diseases classified elsewhere
0.682 0.318 0.000
Y00-Y09 Assault
0.682 0.318 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.682 0.318 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.681 0.319 0.000
M51.3 Other specified intervertebral disk degeneration
0.681 0.319 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.681 0.319 0.000
S92.5 Fracture of other toe
0.681 0.319 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.680 0.320 0.000
D67 Hereditary factor IX deficiency
0.680 0.320 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.680 0.320 0.000
H74 Other disorders of middle ear and mastoid
0.679 0.321 0.000
Q63 Other congenital malformations of kidney
0.679 0.321 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.679 0.321 0.000
S81.7 Multiple open wounds of lower leg
0.679 0.321 0.000
F69 Unspecified disorder of adult personality and behaviour
0.678 0.322 0.000
D68.5 Primary Thrombophilia
0.677 0.323 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.677 0.323 0.000
M25.34 Other instability of joint (Hand)
0.677 0.323 0.000
I44.1 Atrioventricular block, second degree
0.677 0.323 0.000
H71 Cholesteatoma of middle ear
0.676 0.324 0.000
S81.9 Open wound of lower leg, part unspecified
0.676 0.324 0.000
V40-V49 Car occupant injured in transport accident
0.673 0.326 0.000
S98 Traumatic amputation of ankle and foot
0.673 0.327 0.000
S97 Crushing injury of ankle and foot
0.673 0.327 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.673 0.327 0.000
S95 Injury of blood vessels at ankle and foot level
0.673 0.327 0.000
S94 Injury of nerves at ankle and foot level
0.673 0.327 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.673 0.327 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.672 0.328 0.000
H21 Other disorders of iris and ciliary body
0.672 0.328 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.671 0.329 0.000
I30 Acute pericarditis
0.671 0.329 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.671 0.329 0.000
H27 Other disorders of lens
0.670 0.329 0.000
J60-J70 Lung diseases due to external agents
0.670 0.330 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.669 0.331 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.669 0.331 0.000
T42.4 Benzodiazepines
0.668 0.332 0.000
T79.6 Traumatic ischaemia of muscle
0.668 0.332 0.000
D69.9 Haemorrhagic condition, unspecified
0.667 0.333 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.666 0.334 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.666 0.334 0.000
Y83.4 Other reconstructive surgery
0.664 0.336 0.000
G30 Alzheimer's disease
0.664 0.336 0.000
H26.3 Drug-induced cataract
0.663 0.337 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.663 0.337 0.000
A80-A89 Viral infections of the central nervous system
0.662 0.338 0.000
D69.8 Other specified haemorrhagic conditions
0.661 0.339 0.000
D69.2 Other nonthrombocytopenic purpura
0.661 0.339 0.000
D69.1 Qualitative platelet defects
0.661 0.339 0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters
0.661 0.339 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.660 0.339 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.660 0.339 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.660 0.339 0.000
T42.3 Barbiturates
0.660 0.339 0.000
T42.2 Succinimides and oxazolidinediones
0.660 0.339 0.000
T42.0 Hydantoin derivatives
0.660 0.339 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.660 0.340 0.000
F60.9 Personality disorder, unspecified
0.660 0.340 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.659 0.341 0.000
M21.4 Flat foot [pes planus] (acquired)
0.658 0.342 0.000
X50-X57 Overexertion, travel and privation
0.658 0.342 0.000
T50.8 Diagnostic agents
0.657 0.343 0.000
T50.7 Analeptics and opioid receptor antagonists
0.657 0.343 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.657 0.343 0.000
T50.5 Appetite depressants
0.657 0.343 0.000
T50.4 Drugs affecting uric acid metabolism
0.657 0.343 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.657 0.343 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.657 0.343 0.000
T50.1 Loop [high-ceiling] diuretics
0.657 0.343 0.000
T50.0 Mineralocorticoids and their antagonists
0.657 0.343 0.000
G62.9 Polyneuropathy, unspecified
0.657 0.343 0.000
T90.8 Sequelae of other specified injuries of head
0.656 0.344 0.000
T90.3 Sequelae of injury of cranial nerves
0.656 0.344 0.000
T90.1 Sequelae of open wound of head
0.656 0.344 0.000
T90.0 Sequelae of superficial injury of head
0.656 0.344 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.656 0.344 0.000
M25.86 Other specified joint disorders (Lower leg)
0.656 0.344 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.655 0.344 0.000
M25.58 Pain in joint (Other)
0.655 0.345 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.655 0.345 0.000
G72 Other myopathies
0.654 0.346 0.000
I37 Pulmonary valve disorders
0.654 0.346 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.654 0.346 0.000
S89 Other and unspecified injuries of lower leg
0.653 0.347 0.000
S70 Superficial injury of hip and thigh
0.653 0.347 0.000
G71 Primary disorders of muscles
0.653 0.347 0.000
Q07 Other congenital malformations of nervous system
0.653 0.347 0.000
I36 Nonrheumatic tricuspid valve disorders
0.652 0.348 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.651 0.349 0.000
Q50-Q56 Congenital malformations of genital organs
0.650 0.350 0.000
F31.9 Bipolar affective disorder, unspecified
0.650 0.350 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.649 0.351 0.000
M51.9 Intervertebral disk disorder, unspecified
0.649 0.351 0.000
W29 Contact with other powered hand tools and household machinery
0.648 0.352 0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident
0.648 0.352 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.648 0.352 0.000
J18.0 Bronchopneumonia, unspecified
0.647 0.353 0.000
H53-H54 Visual disturbances and blindness
0.647 0.353 0.000
S17 Crushing injury of neck
0.647 0.353 0.000
S15 Injury of blood vessels at neck level
0.647 0.353 0.000
S11 Open wound of neck
0.647 0.353 0.000
S18 Traumatic amputation at neck level
0.647 0.353 0.000
S16 Injury of muscle and tendon at neck level
0.647 0.353 0.000
D69.0 Allergic purpura
0.646 0.354 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.646 0.354 0.000
M25.88 Other specified joint disorders (Other)
0.646 0.354 0.000
M25.83 Other specified joint disorders (Forearm)
0.646 0.354 0.000
M25.82 Other specified joint disorders (Upper arm)
0.646 0.354 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.646 0.354 0.000
M85.0 Fibrous dysplasia (monostotic)
0.646 0.354 0.000
F05.8 Other delirium
0.645 0.355 0.000
F38 Other mood [affective] disorders
0.644 0.356 0.000
F34 Persistent mood [affective] disorders
0.644 0.356 0.000
F39 Unspecified mood [affective] disorder
0.644 0.356 0.000
B19 Unspecified viral hepatitis
0.644 0.356 0.000
G70 Myasthenia gravis and other myoneural disorders
0.644 0.356 0.000
T98 Sequelae of other and unspecified effects of external causes
0.644 0.356 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.643 0.356 0.000
S90.3 Contusion of other and unspecified parts of foot
0.643 0.357 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.643 0.357 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.642 0.358 0.000
J18.9 Pneumonia, unspecified
0.642 0.358 0.000
T90.5 Sequelae of intracranial injury
0.642 0.358 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.641 0.359 0.000
I42.9 Cardiomyopathy, unspecified
0.641 0.359 0.000
D68.4 Acquired coagulation factor deficiency
0.640 0.360 0.000
D68.1 Hereditary factor XI deficiency
0.640 0.360 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.639 0.360 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.639 0.361 0.000
F02 Dementia in other diseases classified elsewhere
0.639 0.361 0.000
F09 Unspecified organic or symptomatic mental disorder
0.639 0.361 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.639 0.361 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.639 0.361 0.000
F80-F89 Disorders of psychological development
0.638 0.362 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.638 0.362 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.637 0.363 0.000
S13.4 Sprain and strain of cervical spine
0.637 0.363 0.000
Q78 Other osteochondrodysplasias
0.636 0.364 0.000
D68.6 Other Thrombophilia
0.636 0.364 0.000
M80 Osteoporosis with pathological fracture
0.635 0.364 0.000
M25.39 Other instability of joint (Site unspecified)
0.635 0.365 0.000
M25.38 Other instability of joint (Other)
0.635 0.365 0.000
M25.36 Other instability of joint (Lower leg)
0.635 0.365 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.635 0.365 0.000
M25.33 Other instability of joint (Forearm)
0.635 0.365 0.000
M25.32 Other instability of joint (Upper arm)
0.635 0.365 0.000
M25.30 Other instability of joint (Multiple sites)
0.635 0.365 0.000
M25.4 Effusion of joint
0.635 0.365 0.000
M21.3 Wrist or foot drop (acquired)
0.635 0.365 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.635 0.365 0.000
M85.8 Other specified disorders of bone density and structure
0.634 0.366 0.000
T40.6 Other and unspecified narcotics
0.633 0.367 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.632 0.368 0.000
X58 Exposure to other specified factors
0.632 0.368 0.000
S10 Superficial injury of neck
0.631 0.368 0.000
Y46.4 Iminostilbenes
0.631 0.369 0.000
H72.8 Other perforations of tympanic membrane
0.631 0.369 0.000
W20 Struck by thrown, projected or falling object
0.631 0.369 0.000
B15 Acute hepatitis A
0.631 0.369 0.000
S92.2 Fracture of other tarsal bone(s)
0.630 0.369 0.000
M62 Other disorders of muscle
0.630 0.370 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.630 0.370 0.000
S92.1 Fracture of talus
0.630 0.370 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.630 0.370 0.000
T39.4 Antirheumatics, not elsewhere classified
0.630 0.370 0.000
T39.2 Pyrazolone derivatives
0.630 0.370 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.630 0.370 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.630 0.370 0.000
M24.03 Loose body in joint (Forearm)
0.629 0.371 0.000
D55-D59 Haemolytic anaemias
0.628 0.372 0.000
S36 Injury of intra-abdominal organs
0.628 0.372 0.000
H25.2 Senile cataract, morgagnian type
0.627 0.372 0.000
M65-M68 Disorders of synovium and tendon
0.627 0.373 0.000
T93.2 Sequelae of other fractures of lower limb
0.627 0.373 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.626 0.373 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.626 0.374 0.000
M81.98 Osteoporosis, unspecified (Other)
0.626 0.374 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.626 0.374 0.000
I31.3 Pericardial effusion (noninflammatory)
0.625 0.375 0.000
S92.7 Multiple fractures of foot
0.625 0.375 0.000
S99 Other and unspecified injuries of ankle and foot
0.625 0.375 0.000
H16 Keratitis
0.624 0.376 0.000
M81.8 Other osteoporosis
0.623 0.377 0.000
M81.6 Localised osteoporosis [Lequesne]
0.623 0.377 0.000
M81.5 Idiopathic osteoporosis
0.623 0.377 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.623 0.377 0.000
M81.2 Osteoporosis of disuse
0.623 0.377 0.000
M81.1 Postoophorectomy osteoporosis
0.623 0.377 0.000
M81.0 Postmenopausal osteoporosis
0.623 0.377 0.000
Y91.9 Alcohol involvement, not otherwise specified
0.623 0.377 0.000
G00 Bacterial meningitis, not elsewhere classified
0.622 0.377 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.621 0.379 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.621 0.379 0.000
T92.0 Sequelae of open wound of upper limb
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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