TreeWAS – Variant ID: rs12591650

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N60.1 Diffuse cystic mastopathy	0.665	0.335	0.000
N60 Benign mammary dysplasia	0.649	0.351	0.000
N60.4 Mammary duct ectasia	0.646	0.354	0.000
N64 Other disorders of breast	0.563	0.437	0.000
N60-N64 Disorders of breast	0.561	0.439	0.000
N64.8 Other specified disorders of breast	0.547	0.453	0.000
N64.5 Other signs and symptoms in breast	0.544	0.456	0.000
N60.2 Fibroadenosis of breast	0.540	0.460	0.000
N64.9 Disorder of breast, unspecified	0.516	0.484	0.000
N60.0 Solitary cyst of breast	0.443	0.557	0.000
N63 Unspecified lump in breast	0.408	0.592	0.000
N64.3 Galactorrhoea not associated with childbirth	0.404	0.596	0.000
N64.2 Atrophy of breast	0.404	0.596	0.000
N64.0 Fissure and fistula of nipple	0.404	0.596	0.000
N60.9 Benign mammary dysplasia, unspecified	0.401	0.599	0.000
N64.1 Fat necrosis of breast	0.305	0.694	0.000
N60.3 Fibrosclerosis of breast	0.256	0.744	0.000
N64.4 Mastodynia	0.220	0.779	0.001
N60.8 Other benign mammary dysplasias	0.206	0.793	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.806	0.194
N62 Hypertrophy of breast	0.180	0.819	0.000
N61 Inflammatory disorders of breast	0.146	0.854	0.000
K41 Femoral hernia	0.000	0.942	0.058
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.958	0.042
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.958	0.042
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.958	0.042
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.958	0.042
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.970	0.030
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
M48.09 Spinal stenosis (Site unspecified)	0.008	0.992	0.000
N75.1 Abscess of Bartholin's gland	0.008	0.992	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.992	0.008
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.993	0.007
I42.0 Dilated cardiomyopathy	0.000	0.993	0.007
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.993	0.007
N75 Diseases of Bartholin's gland	0.006	0.994	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.994	0.006
M48.06 Spinal stenosis (Lumbar region)	0.006	0.994	0.000
I42 Cardiomyopathy	0.000	0.994	0.006
T79.8 Other early complications of trauma	0.000	0.994	0.006
M48.0 Spinal stenosis	0.006	0.994	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.994	0.006
I42.9 Cardiomyopathy, unspecified	0.000	0.994	0.006
G24.9 Dystonia, unspecified	0.005	0.994	0.000
N75.0 Cyst of Bartholin's gland	0.005	0.995	0.000
T79.7 Traumatic subcutaneous emphysema	0.000	0.995	0.005
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.995	0.005
T79.9 Unspecified early complication of trauma	0.000	0.995	0.005
T79.4 Traumatic shock	0.000	0.995	0.005
T79.2 Traumatic secondary and recurrent haemorrhage	0.000	0.995	0.005
T79.1 Fat embolism (traumatic)	0.000	0.995	0.005
T79.0 Air embolism (traumatic)	0.000	0.995	0.005
I42.6 Alcoholic cardiomyopathy	0.000	0.995	0.005
N70.1 Chronic salpingitis and oophoritis	0.005	0.995	0.000
T79.5 Traumatic anuria	0.000	0.995	0.005
G24.5 Blepharospasm	0.005	0.995	0.000
G24 Dystonia	0.005	0.995	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.005	0.995	0.000
N75.8 Other diseases of Bartholin's gland	0.005	0.995	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.995	0.005
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.995	0.004
I42.5 Other restrictive cardiomyopathy	0.000	0.995	0.004
I42.4 Endocardial fibroelastosis	0.000	0.995	0.004
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.995	0.004
M16.1 Other primary coxarthrosis	0.000	0.996	0.004
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.004	0.996	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.004	0.996	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.004	0.996	0.000
Chapter XIV Diseases of the genitourinary system	0.004	0.996	0.000
N70 Salpingitis and oophoritis	0.004	0.996	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.004	0.996	0.000
M48.04 Spinal stenosis (Thoracic region)	0.004	0.996	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
G24.8 Other dystonia	0.004	0.996	0.000
Y40.0 Penicillins	0.004	0.996	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.004	0.996	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.996	0.004
M48.5 Collapsed vertebra, not elsewhere classified	0.004	0.996	0.000
N76.4 Abscess of vulva	0.004	0.996	0.000
M48 Other spondylopathies	0.004	0.996	0.000
I42.8 Other cardiomyopathies	0.000	0.996	0.004
Y40 Systemic antibiotics	0.004	0.996	0.000
G24.4 Idiopathic orofacial dystonia	0.004	0.996	0.000
G24.3 Spasmodic torticollis	0.004	0.996	0.000
G24.2 Idiopathic nonfamilial dystonia	0.004	0.996	0.000
G24.1 Idiopathic familial dystonia	0.004	0.996	0.000
G24.0 Drug-induced dystonia	0.004	0.996	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.004	0.996	0.000
Y45.1 Salicylates	0.004	0.996	0.000
N99-N99 Other disorders of the genitourinary system	0.004	0.996	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.004	0.996	0.000
Y40.8 Other systemic antibiotics	0.004	0.996	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.003	0.996	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.997	0.003
Y40.1 Cefalosporins and other -lactam antibiotics	0.003	0.997	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.997	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.003	0.997	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.003	0.997	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.003	0.997	0.000
N70.0 Acute salpingitis and oophoritis	0.003	0.997	0.000
M48.02 Spinal stenosis (Cervical region)	0.003	0.997	0.000
N10-N16 Renal tubulo-interstitial diseases	0.003	0.997	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.003	0.997	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
Y45.4 Antirheumatics	0.003	0.997	0.000
N00-N08 Glomerular diseases	0.003	0.997	0.000
Y40.3 Macrolides	0.003	0.997	0.000
Y45.8 Other analgesics and antipyretics	0.003	0.997	0.000
N76 Other inflammation of vagina and vulva	0.003	0.997	0.000
N04 Nephrotic syndrome	0.003	0.997	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.003	0.997	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.003	0.997	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.003	0.997	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.003	0.997	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.003	0.997	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.997	0.003
N99.2 Postprocedural adhesions of vagina	0.003	0.997	0.000
M48.9 Spondylopathy, unspecified	0.003	0.997	0.000
M48.8 Other specified spondylopathies	0.003	0.997	0.000
M48.4 Fatigue fracture of vertebra	0.003	0.997	0.000
M48.3 Traumatic spondylopathy	0.003	0.997	0.000
M48.2 Kissing spine	0.003	0.997	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.003	0.997	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.000	0.997	0.003
Y40.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
Y40.6 Rifamycins	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
Y40.4 Tetracyclines	0.003	0.997	0.000
Y40.2 Chloramphenicol group	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
T79-T79 Certain early complications of trauma	0.000	0.997	0.003
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.003	0.997	0.000
S30.2 Contusion of external genital organs	0.003	0.997	0.000
N04.1 Focal and segmental glomerular lesions	0.003	0.997	0.000
N05 Unspecified nephritic syndrome	0.003	0.997	0.000
N04.2 Diffuse membranous glomerulonephritis	0.003	0.997	0.000
T92.1 Sequelae of fracture of arm	0.003	0.997	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.997	0.003
N99.4 Postprocedural pelvic peritoneal adhesions	0.003	0.997	0.000
Y54.3 Benzothiadiazine derivatives	0.003	0.997	0.000
N71 Inflammatory disease of uterus, except cervix	0.003	0.997	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.003	0.997	0.000
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.003	0.997	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.003	0.997	0.000
N25-N29 Other disorders of kidney and ureter	0.002	0.997	0.001
N73 Other female pelvic inflammatory diseases	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
L57.0 Actinic keratosis	0.003	0.997	0.000
S30.0 Contusion of lower back and pelvis	0.003	0.997	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.002	0.997	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.003	0.997	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.003	0.997	0.000
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.002	0.997	0.000
N74.4 Female chlamydial pelvic inflammatory disease	0.002	0.997	0.000
N74.3 Female gonococcal pelvic inflammatory disease	0.002	0.997	0.000
N74.2 Female syphilitic pelvic inflammatory disease	0.002	0.997	0.000
N74.1 Female tuberculous pelvic inflammatory disease	0.002	0.997	0.000
N74.0 Tuberculous infection of cervix uteri	0.002	0.997	0.000
N99.0 Postprocedural renal failure	0.003	0.997	0.000
N25 Disorders resulting from impaired renal tubular function	0.002	0.997	0.000
N05.1 Focal and segmental glomerular lesions	0.003	0.997	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.002	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.003	0.997	0.000
N05.9 Unspecified	0.003	0.997	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.002	0.997	0.000
N06 Isolated proteinuria with specified morphological lesion	0.002	0.997	0.000
N01 Rapidly progressive nephritic syndrome	0.002	0.997	0.000
N00 Acute nephritic syndrome	0.002	0.997	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.002	0.997	0.000
N76.5 Ulceration of vagina	0.002	0.997	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.997	0.003
N76.1 Subacute and chronic vaginitis	0.002	0.997	0.000
S06.00 Concussion (without open intracranial wound)	0.000	0.997	0.003
N04.8 Other	0.002	0.997	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.002	0.997	0.000
N04.6 Dense deposit disease	0.002	0.997	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.997	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.997	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.997	0.000
N04.0 Minor glomerular abnormality	0.002	0.997	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.997	0.000
N15 Other renal tubulo-interstitial diseases	0.002	0.997	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.002	0.997	0.000
N76.3 Subacute and chronic vulvitis	0.002	0.997	0.000
G25.0 Essential tremor	0.002	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.997	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.002	0.998	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.002	0.998	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.002	0.998	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.002	0.998	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.002	0.998	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.002	0.998	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.002	0.998	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.002	0.998	0.000
M48.29 Kissing spine (Site unspecified)	0.002	0.998	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.27 Kissing spine (Lumbosacral region)	0.002	0.998	0.000
M48.26 Kissing spine (Lumbar region)	0.002	0.998	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.002	0.998	0.000
M48.24 Kissing spine (Thoracic region)	0.002	0.998	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.002	0.998	0.000
M48.22 Kissing spine (Cervical region)	0.002	0.998	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.002	0.998	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.002	0.998	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.002	0.998	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.002	0.998	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.002	0.998	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.002	0.998	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.002	0.998	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.002	0.998	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.002	0.998	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.002	0.998	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.002	0.998	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.002	0.998	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.002	0.998	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.002	0.998	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.002	0.998	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.002	0.998	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.002	0.998	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.002	0.998	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.002	0.998	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.002	0.998	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.002	0.998	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.002	0.998	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.002	0.998	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.002	0.998	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.002	0.998	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.002	0.998	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.002	0.998	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.002	0.998	0.000
N99.1 Postprocedural urethral stricture	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.000	0.998	0.002
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.000	0.998	0.002
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.000	0.998	0.002
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.000	0.998	0.002
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.000	0.998	0.002
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.000	0.998	0.002
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.000	0.998	0.002
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.000	0.998	0.002
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.000	0.998	0.002
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
K81.0 Acute cholecystitis	0.002	0.998	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
N73.5 Female pelvic peritonitis, unspecified	0.002	0.998	0.000
N71.0 Acute inflammatory disease of uterus	0.002	0.998	0.000
N04.9 Unspecified	0.002	0.998	0.000
N05.6 Dense deposit disease	0.002	0.998	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N05.0 Minor glomerular abnormality	0.002	0.998	0.000
N11 Chronic tubulo-interstitial nephritis	0.002	0.998	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
G20-G26 Extrapyramidal and movement disorders	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.002	0.998	0.000
N14.3 Nephropathy induced by heavy metals	0.002	0.998	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.002	0.998	0.000
N14.0 Analgesic nephropathy	0.002	0.998	0.000
N99.5 Malfunction of external stoma of urinary tract	0.002	0.998	0.000
N71.1 Chronic inflammatory disease of uterus	0.002	0.998	0.000
N76.6 Ulceration of vulva	0.002	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.002	0.998	0.000
N05.8 Other	0.002	0.998	0.000
S06.8 Other intracranial injuries	0.000	0.998	0.002
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
N20-N23 Urolithiasis	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
N10 Acute tubulo-interstitial nephritis	0.002	0.998	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.002	0.998	0.001
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.002	0.998	0.000
N73.4 Female chronic pelvic peritonitis	0.002	0.998	0.000
N73.3 Female acute pelvic peritonitis	0.002	0.998	0.000
N73.2 Unspecified parametritis and pelvic cellulitis	0.002	0.998	0.000
N73.1 Chronic parametritis and pelvic cellulitis	0.002	0.998	0.000
T93 Sequelae of injuries of lower limb	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
S30.1 Contusion of abdominal wall	0.002	0.998	0.000
N02 Recurrent and persistent haematuria	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.002	0.998	0.000
N25.1 Nephrogenic diabetes insipidus	0.002	0.998	0.000
N25.0 Renal osteodystrophy	0.002	0.998	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.998	0.002
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
N27 Small kidney of unknown cause	0.002	0.998	0.001
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.002	0.998	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.002	0.998	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.002	0.998	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.002	0.998	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.002	0.998	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.002	0.998	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
N76.2 Acute vulvitis	0.002	0.998	0.000
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.002	0.998	0.000
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
N00.9 Unspecified	0.002	0.998	0.000
N00.8 Other	0.002	0.998	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N00.6 Dense deposit disease	0.002	0.998	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N00.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
N00.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
N00.0 Minor glomerular abnormality	0.002	0.998	0.000
N01.9 Unspecified	0.002	0.998	0.000
N01.8 Other	0.002	0.998	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N01.6 Dense deposit disease	0.002	0.998	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N01.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
N01.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
N01.0 Minor glomerular abnormality	0.002	0.998	0.000
N06.9 Unspecified	0.002	0.998	0.000
N06.8 Other	0.002	0.998	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N06.6 Dense deposit disease	0.002	0.998	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N06.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
N06.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
N06.0 Minor glomerular abnormality	0.002	0.998	0.000
N07.9 Unspecified	0.002	0.998	0.000
N07.8 Other	0.002	0.998	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N07.6 Dense deposit disease	0.002	0.998	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N07.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
N07.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
N07.0 Minor glomerular abnormality	0.002	0.998	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
S06.0 Concussion	0.000	0.998	0.002
N21 Calculus of lower urinary tract	0.002	0.998	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.002	0.998	0.000
N15.1 Renal and perinephric abscess	0.002	0.998	0.000
N15.0 Balkan nephropathy	0.002	0.998	0.000
N76.0 Acute vaginitis	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
N02.0 Minor glomerular abnormality	0.002	0.998	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.002	0.998	0.000
N73.0 Acute parametritis and pelvic cellulitis	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
N05.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.002	0.998	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
N21.0 Calculus in bladder	0.002	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
N11.8 Other chronic tubulo-interstitial nephritis	0.002	0.998	0.000
N11.1 Chronic obstructive pyelonephritis	0.002	0.998	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
G23 Other degenerative diseases of basal ganglia	0.002	0.998	0.000
G21 Secondary Parkinsonism	0.002	0.998	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.002	0.998	0.000
G22 Parkinsonism in diseases classified elsewhere	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
N02.8 Other	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.998	0.002
N26 Unspecified contracted kidney	0.001	0.998	0.001
N99.3 Prolapse of vaginal vault after hysterectomy	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.998	0.002
G25.2 Other specified forms of tremor	0.002	0.998	0.000
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.001
N29.0 Late syphilis of kidney	0.001	0.998	0.001
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.002	0.998	0.000
N27.1 Small kidney, bilateral	0.001	0.998	0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.001	0.998	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
I67.9 Cerebrovascular disease, unspecified	0.002	0.998	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N02.6 Dense deposit disease	0.002	0.998	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N02.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
N02.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.998	0.002
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Z83.3 Family history of diabetes mellitus	0.000	0.998	0.002
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
N27.9 Small kidney, unspecified	0.001	0.998	0.001
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.998	0.000
N21.1 Calculus in urethra	0.002	0.998	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.998	0.002
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.998	0.002
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations