TreeWAS – Variant ID: rs12610185

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K76.0 Fatty (change of) liver, not elsewhere classified	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
K76 Other diseases of liver	1.000	0.000	0.000
Chapter XX External causes of morbidity and mortality	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
K70-K77 Diseases of liver	0.999	0.001	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001	0.000
E10-E14 Diabetes mellitus	0.999	0.001	0.000
E11 Non-insulin-dependent diabetes mellitus	0.999	0.001	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.002	0.998
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.995	0.005	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.995	0.005	0.000
O42 Premature rupture of membranes	0.993	0.007	0.000
Chapter XI Diseases of the digestive system	0.993	0.007	0.000
O42.9 Premature rupture of membranes, unspecified	0.991	0.009	0.000
E20-E35 Disorders of other endocrine glands	0.984	0.016	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.980	0.020	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.980	0.020	0.000
W00-W19 Falls	0.976	0.024	0.000
E23 Hypofunction and other disorders of pituitary gland	0.974	0.026	0.000
Chapter VIII Diseases of the ear and mastoid process	0.971	0.029	0.000
K74 Fibrosis and cirrhosis of liver	0.963	0.037	0.000
Chapter VII Diseases of the eye and adnexa	0.960	0.040	0.000
H53-H54 Visual disturbances and blindness	0.959	0.041	0.000
K76.6 Portal hypertension	0.953	0.047	0.000
H65-H75 Diseases of middle ear and mastoid	0.953	0.047	0.000
K50-K52 Noninfective enteritis and colitis	0.953	0.047	0.000
K74.6 Other and unspecified cirrhosis of liver	0.949	0.051	0.000
K51 Ulcerative colitis	0.949	0.051	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.947	0.053	0.000
H53 Visual disturbances	0.943	0.057	0.000
E23.0 Hypopituitarism	0.940	0.060	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.938	0.062	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.936	0.064	0.000
H54 Blindness and low vision	0.933	0.067	0.000
H72 Perforation of tympanic membrane	0.926	0.074	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.917	0.083	0.000
K51.2 Ulcerative (chronic) proctitis	0.914	0.086	0.000
E23.2 Diabetes insipidus	0.910	0.090	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.907	0.093	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.907	0.093	0.000
O40 Polyhydramnios	0.893	0.107	0.000
H54.4 Blindness, one eye	0.892	0.108	0.000
O85-O92 Complications predominantly related to the puerperium	0.891	0.109	0.000
H53.8 Other visual disturbances	0.886	0.114	0.000
W20-W49 Exposure to inanimate mechanical forces	0.883	0.117	0.000
Y42.7 Androgens and anabolic congeners	0.880	0.120	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.877	0.123	0.000
K70 Alcoholic liver disease	0.876	0.124	0.000
E24 Cushing's syndrome	0.873	0.127	0.000
Y44 Agents primarily affecting blood constituents	0.873	0.127	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.868	0.132	0.000
W50-W64 Exposure to animate mechanical forces	0.867	0.133	0.000
Chapter I Certain infectious and parasitic diseases	0.866	0.134	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.866	0.134	0.000
E11.0 With coma	0.863	0.137	0.000
S60-S69 Injuries to the wrist and hand	0.863	0.137	0.000
W17 Other fall from one level to another	0.861	0.139	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.859	0.141	0.000
W13 Fall from, out of or through building or structure	0.857	0.143	0.000
H53.4 Visual field defects	0.856	0.144	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.852	0.148	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.849	0.151	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.848	0.152	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.846	0.154	0.000
W19 Unspecified fall	0.845	0.155	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.844	0.156	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.840	0.160	0.000
H90-H95 Other disorders of ear	0.838	0.162	0.000
T79-T79 Certain early complications of trauma	0.832	0.168	0.000
Y00-Y09 Assault	0.829	0.171	0.000
K75 Other inflammatory liver diseases	0.826	0.174	0.000
H55-H59 Other disorders of eye and adnexa	0.820	0.180	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.817	0.183	0.000
H71 Cholesteatoma of middle ear	0.815	0.185	0.000
S50-S59 Injuries to the elbow and forearm	0.814	0.186	0.000
Y40 Systemic antibiotics	0.812	0.188	0.000
X50-X57 Overexertion, travel and privation	0.811	0.189	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.809	0.191	0.000
H53.2 Diplopia	0.808	0.192	0.000
X10-X19 Contact with heat and hot substances	0.808	0.192	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.805	0.195	0.000
W19.4 Street and highway	0.804	0.196	0.000
T42.4 Benzodiazepines	0.797	0.203	0.000
K51.9 Ulcerative colitis, unspecified	0.796	0.204	0.000
Q50-Q56 Congenital malformations of genital organs	0.796	0.204	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.795	0.205	0.000
H54.7 Unspecified visual loss	0.795	0.205	0.000
T40.4 Other synthetic narcotics	0.795	0.205	0.000
E11.8 With unspecified complications	0.793	0.207	0.000
O44 Placenta praevia	0.792	0.208	0.000
W02.9 Unspecified place	0.791	0.209	0.000
S10-S19 Injuries to the neck	0.790	0.210	0.000
K35-K38 Diseases of appendix	0.789	0.211	0.000
O47 False labour	0.789	0.211	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.787	0.212	0.000
V10-V19 Pedal cyclist injured in transport accident	0.787	0.213	0.000
H72.0 Central perforation of tympanic membrane	0.780	0.220	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.780	0.220	0.000
H72.8 Other perforations of tympanic membrane	0.775	0.225	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.774	0.226	0.000
K51.8 Other ulcerative colitis	0.774	0.226	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.773	0.227	0.000
W20 Struck by thrown, projected or falling object	0.773	0.227	0.000
S90-S99 Injuries to the ankle and foot	0.773	0.227	0.000
X60-X84 Intentional self-harm	0.772	0.228	0.000
K75.8 Other specified inflammatory liver diseases	0.771	0.229	0.000
Y48 Anaesthetics and therapeutic gases	0.771	0.229	0.000
W13.9 Unspecified place	0.771	0.229	0.000
Y44.2 Anticoagulants	0.771	0.229	0.000
E28 Ovarian dysfunction	0.770	0.230	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.768	0.232	0.000
O43 Placental disorders	0.764	0.236	0.000
K51.5 Mucosal proctocolitis	0.764	0.236	0.000
T40.6 Other and unspecified narcotics	0.764	0.236	0.000
H70 Mastoiditis and related conditions	0.763	0.237	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.762	0.238	0.000
E40-E46 Malnutrition	0.759	0.241	0.000
V40-V49 Car occupant injured in transport accident	0.759	0.241	0.000
B99-B99 Other infectious diseases	0.757	0.243	0.000
K35 Acute appendicitis	0.755	0.245	0.000
E13 Other specified diabetes mellitus	0.753	0.247	0.000
E34 Other endocrine disorders	0.752	0.248	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.752	0.248	0.000
E23.7 Disorder of pituitary gland, unspecified	0.752	0.248	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.750	0.250	0.000
K73 Chronic hepatitis, not elsewhere classified	0.749	0.251	0.000
H54.6 Unqualified visual loss, one eye	0.749	0.251	0.000
K70.4 Alcoholic hepatic failure	0.747	0.253	0.000
B25-B34 Other viral diseases	0.747	0.253	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.744	0.256	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.744	0.256	0.000
K65-K67 Diseases of peritoneum	0.743	0.257	0.000
K35.8 Acute appendicitis, other and unspecified	0.743	0.257	0.000
Y52 Agents primarily affecting the cardiovascular system	0.741	0.259	0.000
E24.0 Pituitary-dependent Cushing's disease	0.741	0.259	0.000
H93 Other disorders of ear, not elsewhere classified	0.741	0.259	0.000
H30-H36 Disorders of choroid and retina	0.740	0.260	0.000
H74 Other disorders of middle ear and mastoid	0.739	0.261	0.000
H66 Suppurative and unspecified otitis media	0.737	0.263	0.000
V98-V99 Other and unspecified transport accidents	0.735	0.265	0.000
H53.9 Visual disturbance, unspecified	0.734	0.266	0.000
W18 Other fall on same level	0.732	0.268	0.000
S64 Injury of nerves at wrist and hand level	0.731	0.269	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.730	0.270	0.000
B15-B19 Viral hepatitis	0.729	0.271	0.000
S51 Open wound of forearm	0.729	0.271	0.000
O86 Other puerperal infections	0.728	0.272	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.727	0.273	0.000
E11.1 With ketoacidosis	0.726	0.274	0.000
E24.9 Cushing's syndrome, unspecified	0.726	0.274	0.000
W17.4 Street and highway	0.725	0.275	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.725	0.275	0.000
O87 Venous complications in the puerperium	0.725	0.275	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.723	0.277	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.723	0.277	0.000
H90 Conductive and sensorineural hearing loss	0.719	0.281	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.718	0.282	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.717	0.283	0.000
W10 Fall on and from stairs and steps	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
K76.5 Hepatic veno-occlusive disease	0.717	0.283	0.000
K76.4 Peliosis hepatis	0.717	0.283	0.000
K76.3 Infarction of liver	0.717	0.283	0.000
K76.2 Central haemorrhagic necrosis of liver	0.717	0.283	0.000
K76.1 Chronic passive congestion of liver	0.717	0.283	0.000
Y35-Y36 Legal intervention and operations of war	0.717	0.283	0.000
Y10-Y34 Event of undetermined intent	0.717	0.283	0.000
X85-X99 Assault	0.717	0.283	0.000
X30-X39 Exposure to forces of nature	0.717	0.283	0.000
X00-X09 Exposure to smoke, fire and flames	0.717	0.283	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283	0.000
W75-W84 Other accidental threats to breathing	0.717	0.283	0.000
W65-W74 Accidental drowning and submersion	0.717	0.283	0.000
V95-V97 Air and space transport accidents	0.717	0.283	0.000
V90-V94 Water transport accidents	0.717	0.283	0.000
V70-V79 Bus occupant injured in transport accident	0.717	0.283	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283	0.000
V01-V09 Pedestrian injured in transport accident	0.717	0.283	0.000
K77 Liver disorders in diseases classified elsewhere	0.717	0.283	0.000
K71 Toxic liver disease	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.716	0.284	0.000
E11.7 With multiple complications	0.716	0.284	0.000
T00-T07 Injuries involving multiple body regions	0.715	0.285	0.000
T43.2 Other and unspecified antidepressants	0.714	0.286	0.000
O31 Complications specific to multiple gestation	0.714	0.286	0.000
O34.4 Maternal care for other abnormalities of cervix	0.713	0.287	0.000
S31 Open wound of abdomen, lower back and pelvis	0.712	0.287	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.712	0.287	0.000
O33 Maternal care for known or suspected disproportion	0.712	0.288	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.712	0.288	0.000
E10 Insulin-dependent diabetes mellitus	0.711	0.289	0.000
W19.3 Sports and athletics area	0.711	0.289	0.000
Q80-Q89 Other congenital malformations	0.710	0.289	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.710	0.290	0.000
Y95 Nosocomial condition	0.707	0.293	0.000
H55 Nystagmus and other irregular eye movements	0.707	0.293	0.000
K76.8 Other specified diseases of liver	0.706	0.294	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.705	0.294	0.000
E32 Diseases of thymus	0.705	0.294	0.000
E31 Polyglandular dysfunction	0.705	0.294	0.000
E30 Disorders of puberty, not elsewhere classified	0.705	0.294	0.000
E25 Adrenogenital disorders	0.705	0.294	0.000
E20 Hypoparathyroidism	0.705	0.294	0.000
W17.5 Trade and service area	0.705	0.295	0.000
Y59 Other and unspecified vaccines and biological substances	0.703	0.297	0.000
Y58 Bacterial vaccines	0.703	0.297	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.703	0.297	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.703	0.297	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.703	0.297	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.703	0.297	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.702	0.297	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.702	0.297	0.000
O34.6 Maternal care for abnormality of vagina	0.702	0.297	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.702	0.297	0.000
O34.3 Maternal care for cervical incompetence	0.702	0.297	0.000
O34.0 Maternal care for congenital malformation of uterus	0.702	0.297	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.701	0.299	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.700	0.300	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.700	0.300	0.000
W14 Fall from tree	0.700	0.300	0.000
W12 Fall on and from scaffolding	0.700	0.300	0.000
W11 Fall on and from ladder	0.700	0.300	0.000
W09 Fall involving playground equipment	0.700	0.300	0.000
W05 Fall involving wheelchair	0.700	0.300	0.000
W04 Fall while being carried or supported by other persons	0.700	0.300	0.000
W00 Fall on same level involving ice and snow	0.700	0.300	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.700	0.300	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.699	0.301	0.000
E11.3 With ophthalmic complications	0.699	0.301	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.698	0.302	0.000
E23.1 Drug-induced hypopituitarism	0.698	0.302	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.698	0.302	0.000
O45 Premature separation of placenta [abruptio placentae]	0.698	0.302	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.696	0.304	0.000
Y04 Assault by bodily force	0.696	0.304	0.000
W20.0 Home	0.694	0.306	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.693	0.306	0.000
S12 Fracture of neck	0.692	0.308	0.000
B95-B98 Bacterial, viral and other infectious agents	0.691	0.309	0.000
W15 Fall from cliff	0.691	0.309	0.000
K74.4 Secondary biliary cirrhosis	0.690	0.310	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.690	0.310	0.000
K74.1 Hepatic sclerosis	0.690	0.310	0.000
A65-A69 Other spirochaetal diseases	0.690	0.310	0.000
O89 Complications of anaesthesia during the puerperium	0.689	0.311	0.000
E14 Unspecified diabetes mellitus	0.689	0.311	0.000
Y45.1 Salicylates	0.689	0.311	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.688	0.312	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.688	0.312	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.688	0.312	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.688	0.312	0.000
O47.9 False labour, unspecified	0.687	0.313	0.000
Y44.5 Thrombolytic drugs	0.687	0.313	0.000
B34 Viral infection of unspecified site	0.686	0.314	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.686	0.314	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.685	0.315	0.000
H43-H45 Disorders of vitreous body and globe	0.685	0.315	0.000
H54.9 Unspecified visual impairment (binocular)	0.684	0.316	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.683	0.317	0.000
H68 Eustachian salpingitis and obstruction	0.683	0.317	0.000
H67 Otitis media in diseases classified elsewhere	0.683	0.317	0.000
X51 Travel and motion	0.683	0.317	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.682	0.317	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.682	0.318	0.000
O34.1 Maternal care for tumour of corpus uteri	0.681	0.318	0.000
B35-B49 Mycoses	0.681	0.319	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.681	0.319	0.000
Q24 Other congenital malformations of heart	0.681	0.319	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.680	0.320	0.000
B99 Other and unspecified infectious diseases	0.679	0.321	0.000
T33-T35 Frostbite	0.679	0.321	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.679	0.321	0.000
E50-E64 Other nutritional deficiencies	0.676	0.323	0.000
Q23 Congenital malformations of aortic and mitral valves	0.676	0.324	0.000
O41 Other disorders of amniotic fluid and membranes	0.676	0.324	0.000
H53.6 Night blindness	0.676	0.324	0.000
H53.5 Colour vision deficiencies	0.676	0.324	0.000
H53.3 Other disorders of binocular vision	0.676	0.324	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.675	0.325	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.673	0.326	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.673	0.327	0.000
K70.9 Alcoholic liver disease, unspecified	0.673	0.327	0.000
O90 Complications of the puerperium, not elsewhere classified	0.671	0.329	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.671	0.329	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.671	0.329	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.671	0.329	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.671	0.329	0.000
X10 Contact with hot drinks, food, fats and cooking oils	0.670	0.329	0.000
K35.3 Acute appendicitis with localized peritonitis	0.669	0.331	0.000
H54.5 Low vision, one eye	0.669	0.331	0.000
H54.3 Unqualified visual loss, both eyes	0.669	0.331	0.000
H54.2 Low vision, both eyes	0.669	0.331	0.000
H54.1 Blindness, one eye, low vision, other eye	0.669	0.331	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.667	0.333	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.665	0.335	0.000
K74.0 Hepatic fibrosis	0.665	0.335	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.664	0.336	0.000
H72.2 Other marginal perforations of tympanic membrane	0.664	0.336	0.000
H72.1 Attic perforation of tympanic membrane	0.664	0.336	0.000
S68 Traumatic amputation of wrist and hand	0.664	0.336	0.000
S36 Injury of intra-abdominal organs	0.663	0.337	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.662	0.338	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.661	0.339	0.000
W29 Contact with other powered hand tools and household machinery	0.661	0.339	0.000
E23.6 Other disorders of pituitary gland	0.661	0.339	0.000
T42.1 Iminostilbenes	0.661	0.339	0.000
V80-V89 Other land transport accidents	0.660	0.339	0.000
X59 Exposure to unspecified factor	0.660	0.340	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.659	0.341	0.000
H53.0 Amblyopia ex anopsia	0.659	0.341	0.000
Y40.0 Penicillins	0.659	0.341	0.000
W08 Fall involving other furniture	0.658	0.342	0.000
K51.4 Pseudopolyposis of colon	0.657	0.342	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.657	0.342	0.000
Q35-Q37 Cleft lip and cleft palate	0.657	0.342	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.657	0.342	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.657	0.342	0.000
Q51 Congenital malformations of uterus and cervix	0.657	0.343	0.000
W44 Foreign body entering into or through eye or natural orifice	0.656	0.344	0.000
K70.0 Alcoholic fatty liver	0.655	0.345	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.655	0.345	0.000
Q00-Q07 Congenital malformations of the nervous system	0.655	0.345	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.654	0.346	0.000
K70.1 Alcoholic hepatitis	0.654	0.346	0.000
S65 Injury of blood vessels at wrist and hand level	0.654	0.346	0.000
E11.6 With other specified complications	0.653	0.347	0.000
X20-X29 Contact with venomous animals and plants	0.653	0.347	0.000
O00-O08 Pregnancy with abortive outcome	0.645	0.347	0.008
E26 Hyperaldosteronism	0.651	0.349	0.000
Y42.9 Other and unspecified hormone antagonists	0.650	0.349	0.000
Y42.4 Oral contraceptives	0.650	0.349	0.000
Y42.2 Antithyroid drugs	0.650	0.349	0.000
Y42.1 Thyroid hormones and substitutes	0.650	0.349	0.000
H73 Other disorders of tympanic membrane	0.650	0.350	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.649	0.351	0.000
Y57 Other and unspecified drugs and medicaments	0.648	0.352	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.648	0.352	0.000
S90 Superficial injury of ankle and foot	0.647	0.353	0.000
Y40.8 Other systemic antibiotics	0.646	0.354	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.645	0.355	0.000
W07 Fall involving chair	0.645	0.355	0.000
T42.0 Hydantoin derivatives	0.644	0.356	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.643	0.357	0.000
A15-A19 Tuberculosis	0.642	0.358	0.000
T79.6 Traumatic ischaemia of muscle	0.641	0.359	0.000
T36 Poisoning by systemic antibiotics	0.641	0.359	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.639	0.361	0.000
O91 Infections of breast associated with childbirth	0.639	0.361	0.000
O88 Obstetric embolism	0.639	0.361	0.000
O85 Puerperal sepsis	0.639	0.361	0.000
H93.1 Tinnitus	0.638	0.362	0.000
Q25 Congenital malformations of great arteries	0.636	0.364	0.000
S56 Injury of muscle and tendon at forearm level	0.635	0.365	0.000
E11.2 With renal complications	0.635	0.365	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.635	0.365	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.634	0.365	0.000
K72 Hepatic failure, not elsewhere classified	0.633	0.367	0.000
W46 Contact with hypodermic needle	0.633	0.367	0.000
W45 Foreign body or object entering through skin	0.633	0.367	0.000
W43 Exposure to vibration	0.633	0.367	0.000
W42 Exposure to noise	0.633	0.367	0.000
W41 Exposure to high-pressure jet	0.633	0.367	0.000
W40 Explosion of other materials	0.633	0.367	0.000
W39 Discharge of firework	0.633	0.367	0.000
W38 Explosion and rupture of other specified pressurised devices	0.633	0.367	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.633	0.367	0.000
W36 Explosion and rupture of gas cylinder	0.633	0.367	0.000
W35 Explosion and rupture of boiler	0.633	0.367	0.000
W34 Discharge from other and unspecified firearms	0.633	0.367	0.000
W33 Rifle, shotgun and larger firearm discharge	0.633	0.367	0.000
W32 Handgun discharge	0.633	0.367	0.000
W31 Contact with other and unspecified machinery	0.633	0.367	0.000
W30 Contact with agricultural machinery	0.633	0.367	0.000
W28 Contact with powered lawn mower	0.633	0.367	0.000
W27 Contact with nonpowered hand tool	0.633	0.367	0.000
W26 Contact with knife, sword or dagger	0.633	0.367	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.633	0.367	0.000
K74.5 Biliary cirrhosis, unspecified	0.629	0.370	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.629	0.371	0.000
T40.8 Lysergide [LSD]	0.629	0.371	0.000
T40.7 Cannabis (derivatives)	0.629	0.371	0.000
T40.5 Cocaine	0.629	0.371	0.000
T40.3 Methadone	0.629	0.371	0.000
T40.1 Heroin	0.629	0.371	0.000
T40.0 Opium	0.629	0.371	0.000
W17.6 Industrial and construction area	0.629	0.371	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.628	0.372	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.627	0.373	0.000
H70.9 Mastoiditis, unspecified	0.627	0.373	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.627	0.373	0.000
V11 Pedal cyclist injured in collision with other pedal cycle	0.627	0.373	0.000
E24.8 Other Cushing's syndrome	0.626	0.374	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.626	0.374	0.000
E24.3 Ectopic ACTH syndrome	0.626	0.374	0.000
E24.2 Drug-induced Cushing's syndrome	0.626	0.374	0.000
E24.1 Nelson's syndrome	0.626	0.374	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.626	0.374	0.000
Y44.7 Plasma substitutes	0.626	0.374	0.000
Y44.6 Natural blood and blood products	0.626	0.374	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.626	0.374	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.626	0.374	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.626	0.374	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.626	0.374	0.000
O44.1 Placenta praevia with haemorrhage	0.625	0.375	0.000
V10 Pedal cyclist injured in collision with pedestrian or animal	0.625	0.375	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.625	0.375	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.623	0.377	0.000
W02.8 Other specified place	0.622	0.377	0.000
W02.3 Sports and athletics area	0.622	0.377	0.000
W02.7 Farm	0.622	0.377	0.000
W02.6 Industrial and construction area	0.622	0.377	0.000
W02.5 Trade and service area	0.622	0.377	0.000
W02.4 Street and highway	0.622	0.377	0.000
W02.2 School, other institution and public administrative area	0.622	0.377	0.000
W02.1 Residential institution	0.622	0.377	0.000
W02.0 Home	0.622	0.377	0.000
A00-A09 Intestinal infectious diseases	0.622	0.378	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.622	0.378	0.000
W64 Exposure to other and unspecified animate mechanical forces	0.622	0.378	0.000
W59 Bitten or crushed by other reptiles	0.622	0.378	0.000
W58 Bitten or struck by crocodile or alligator	0.622	0.378	0.000
W56 Contact with marine animal	0.622	0.378	0.000
W54 Bitten or struck by dog	0.622	0.378	0.000
W53 Bitten by rat	0.622	0.378	0.000
W52 Crushed, pushed and stepped on by crowd or human stampede	0.622	0.378	0.000
W51 Striking against or bumped into by another person	0.622	0.378	0.000
Y48.2 Other and unspecified general anaesthetics	0.622	0.378	0.000
S64.4 Injury of digital nerve of other finger	0.622	0.378	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.622	0.378	0.000
S51.7 Multiple open wounds of forearm	0.621	0.379	0.000
H66.4 Suppurative otitis media, unspecified	0.621	0.379	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.621	0.379	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.621	0.379	0.000
A75-A79 Rickettsioses	0.621	0.379	0.000
A70-A74 Other diseases caused by chlamydiae	0.621	0.379	0.000
A20-A28 Certain zoonotic bacterial diseases	0.621	0.379	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.620	0.379	0.000
O43.8 Other placental disorders	0.620	0.380	0.000
O86.2 Urinary tract infection following delivery	0.620	0.380	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.619	0.381	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.619	0.381	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.618	0.382	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.617	0.383	0.000
W17.9 Unspecified place	0.617	0.383	0.000
W17.8 Other specified place	0.617	0.383	0.000
W17.0 Home	0.617	0.383	0.000
W17.7 Farm	0.617	0.383	0.000
W17.3 Sports and athletics area	0.617	0.383	0.000
W17.2 School, other institution and public administrative area	0.617	0.383	0.000
W17.1 Residential institution	0.617	0.383	0.000
K70.3 Alcoholic cirrhosis of liver	0.617	0.383	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.616	0.384	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.616	0.384	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.616	0.384	0.000
T42.3 Barbiturates	0.616	0.384	0.000
T42.2 Succinimides and oxazolidinediones	0.616	0.384	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.615	0.385	0.000
W21 Striking against or struck by sports equipment	0.615	0.385	0.000
W13.8 Other specified place	0.614	0.386	0.000
W13.0 Home	0.614	0.386	0.000
W13.7 Farm	0.614	0.386	0.000
W13.6 Industrial and construction area	0.614	0.386	0.000
W13.5 Trade and service area	0.614	0.386	0.000
W13.4 Street and highway	0.614	0.386	0.000
W13.3 Sports and athletics area	0.614	0.386	0.000
W13.2 School, other institution and public administrative area	0.614	0.386	0.000
W13.1 Residential institution	0.614	0.386	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.614	0.386	0.000
Y00 Assault by blunt object	0.614	0.386	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.613	0.387	0.000
K75.9 Inflammatory liver disease, unspecified	0.613	0.387	0.000
V17 Pedal cyclist injured in collision with fixed or stationary object	0.613	0.387	0.000
H60-H62 Diseases of external ear	0.613	0.387	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.612	0.388	0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.610	0.390	0.000
B50-B64 Protozoal diseases	0.610	0.390	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.610	0.390	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.609	0.391	0.000
Y98 Lifestyle-related condition	0.609	0.391	0.000
Y97 Environmental-pollution-related condition	0.609	0.391	0.000
Y96 Work-related condition	0.609	0.391	0.000
O00 Ectopic pregnancy	0.605	0.391	0.003
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.607	0.393	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.607	0.393	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.607	0.393	0.000
V20-V29 Motorcycle rider injured in transport accident	0.606	0.393	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.606	0.393	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.606	0.394	0.000
W19.8 Other specified place	0.606	0.394	0.000
W19.5 Trade and service area	0.606	0.394	0.000
W19.0 Home	0.606	0.394	0.000
W19.7 Farm	0.606	0.394	0.000
W19.6 Industrial and construction area	0.606	0.394	0.000
O87.2 Haemorrhoids in the puerperium	0.606	0.394	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.605	0.395	0.000
T43.9 Psychotropic drug, unspecified	0.605	0.395	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.605	0.395	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations