TreeWAS – Variant ID: rs12628463

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.108	0.892
M15-M19 Arthrosis	0.108	0.892
# Top node	0.107	0.893
M17 Gonarthrosis [arthrosis of knee]	0.105	0.895
Chapter X Diseases of the respiratory system	0.104	0.896
M19 Other arthrosis	0.102	0.898
Chapter VII Diseases of the eye and adnexa	0.101	0.899
M20-M25 Other joint disorders	0.099	0.901
M17.0 Primary gonarthrosis, bilateral	0.099	0.901
Chapter XIV Diseases of the genitourinary system	0.096	0.904
J30-J39 Other diseases of upper respiratory tract	0.095	0.905
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.095	0.905
Chapter XII Diseases of the skin and subcutaneous tissue	0.094	0.906
M19.9 Arthrosis, unspecified	0.094	0.906
Chapter IX Diseases of the circulatory system	0.093	0.907
H30-H36 Disorders of choroid and retina	0.093	0.907
M23 Internal derangement of knee	0.092	0.908
N17-N19 Renal failure	0.090	0.910
Chapter VIII Diseases of the ear and mastoid process	0.088	0.912
L80-L99 Other disorders of the skin and subcutaneous tissue	0.088	0.912
J60-J70 Lung diseases due to external agents	0.087	0.913
I60-I69 Cerebrovascular diseases	0.087	0.913
M17.1 Other primary gonarthrosis	0.087	0.913
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.086	0.914
Chapter I Certain infectious and parasitic diseases	0.086	0.914
H35 Other retinal disorders	0.085	0.915
Chapter V Mental and behavioural disorders	0.085	0.915
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.085	0.915
M19.0 Primary arthrosis of other joints	0.085	0.915
M17.9 Gonarthrosis, unspecified	0.084	0.915
J40-J47 Chronic lower respiratory diseases	0.084	0.916
M65-M68 Disorders of synovium and tendon	0.084	0.916
I83 Varicose veins of lower extremities	0.083	0.917
M19.97 Arthrosis, unspecified (Ankle and foot)	0.083	0.917
J90-J94 Other diseases of pleura	0.083	0.917
N40-N51 Diseases of male genital organs	0.083	0.917
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.082	0.917
J35 Chronic diseases of tonsils and adenoids	0.082	0.918
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.082	0.918
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.081	0.919
J80-J84 Other respiratory diseases principally affecting the interstitium	0.081	0.919
I63 Cerebral infarction	0.080	0.920
Chapter IV Endocrine, nutritional and metabolic diseases	0.080	0.920
N19 Unspecified renal failure	0.080	0.920
M40-M43 Deforming dorsopathies	0.079	0.921
N60-N64 Disorders of breast	0.079	0.921
S80-S89 Injuries to the knee and lower leg	0.079	0.921
J09-J18 Influenza and pneumonia	0.079	0.921
H04 Disorders of lachrymal system	0.078	0.921
I70-I79 Diseases of arteries, arterioles and capillaries	0.078	0.922
M23.2 Derangement of meniscus due to old tear or injury	0.078	0.922
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.078	0.922
M91-M94 Chondropathies	0.078	0.922
M86-M90 Other osteopathies	0.078	0.922
M60-M63 Disorders of muscles	0.078	0.922
M00-M03 Infectious arthropathies	0.078	0.922
M15 Polyarthrosis	0.078	0.922
H35.8 Other specified retinal disorders	0.077	0.923
Chapter XX External causes of morbidity and mortality	0.077	0.923
Chapter XXII Codes for special purposes	0.077	0.923
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.077	0.923
Chapter XVI Certain conditions originating in the perinatal period	0.077	0.923
M70-M79 Other soft tissue disorders	0.077	0.923
M19.94 Arthrosis, unspecified (Hand)	0.076	0.924
S60-S69 Injuries to the wrist and hand	0.076	0.924
J32 Chronic sinusitis	0.076	0.924
M05-M14 Inflammatory polyarthropathies	0.076	0.924
M23.8 Other internal derangements of knee	0.076	0.924
J20-J22 Other acute lower respiratory infections	0.076	0.924
I63.9 Cerebral infarction, unspecified	0.076	0.924
M17.5 Other secondary gonarthrosis	0.075	0.924
M17.4 Other secondary gonarthrosis, bilateral	0.075	0.924
M17.3 Other posttraumatic gonarthrosis	0.075	0.924
M17.2 Posttraumatic gonarthrosis, bilateral	0.075	0.924
H53-H54 Visual disturbances and blindness	0.075	0.925
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.075	0.925
L91 Hypertrophic disorders of skin	0.075	0.925
L90 Atrophic disorders of skin	0.075	0.925
M18 Arthrosis of first carpometacarpal joint	0.074	0.925
H43-H45 Disorders of vitreous body and globe	0.074	0.926
M25 Other joint disorders, not elsewhere classified	0.074	0.926
N17 Acute renal failure	0.074	0.926
S20-S29 Injuries to the thorax	0.074	0.926
E70-E90 Metabolic disorders	0.074	0.926
M23.4 Loose body in knee	0.074	0.926
M19.8 Other specified arthrosis	0.073	0.927
M19.2 Other secondary arthrosis	0.073	0.927
M19.1 Posttraumatic arthrosis of other joints	0.073	0.927
J00-J06 Acute upper respiratory infections	0.073	0.927
I67 Other cerebrovascular diseases	0.073	0.927
M35 Other systemic involvement of connective tissue	0.073	0.927
H55-H59 Other disorders of eye and adnexa	0.073	0.927
H46-H48 Disorders of optic nerve and visual pathways	0.073	0.927
H10-H13 Disorders of conjunctiva	0.073	0.927
F40-F48 Neurotic, stress-related and somatoform disorders	0.073	0.927
N18 Chronic renal failure	0.073	0.927
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.072	0.927
H33 Retinal detachments and breaks	0.072	0.927
M80-M85 Disorders of bone density and structure	0.072	0.927
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.072	0.928
J35.1 Hypertrophy of tonsils	0.072	0.928
N20-N23 Urolithiasis	0.072	0.928
H90-H95 Other disorders of ear	0.071	0.929
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.071	0.929
M34 Systemic sclerosis	0.071	0.929
M33 Dermatopolymyositis	0.071	0.929
M32 Systemic lupus erythematosus	0.071	0.929
M31 Other necrotising vasculopathies	0.071	0.929
M30 Polyarteritis nodosa and related conditions	0.071	0.929
M24 Other specific joint derangements	0.071	0.929
M22 Disorders of patella	0.071	0.929
M21 Other acquired deformities of limbs	0.071	0.929
L82 Seborrhoeic keratosis	0.071	0.929
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.071	0.929
T36-T50 Poisoning by drugs, medicaments and biological substances	0.071	0.929
J38.0 Paralysis of vocal cords and larynx	0.071	0.929
L20-L30 Dermatitis and eczema	0.071	0.929
N00-N08 Glomerular diseases	0.071	0.929
M45-M49 Spondylopathies	0.070	0.929
N10-N16 Renal tubulo-interstitial diseases	0.070	0.930
M19.91 Arthrosis, unspecified (Shoulder region)	0.070	0.930
M20 Acquired deformities of fingers and toes	0.070	0.930
L97 Ulcer of lower limb, not elsewhere classified	0.070	0.930
H04.5 Stenosis and insufficiency of lachrymal passages	0.070	0.930
H35.3 Degeneration of macula and posterior pole	0.070	0.930
M19.99 Arthrosis, unspecified (Site unspecified)	0.069	0.931
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.069	0.931
H25-H28 Disorders of lens	0.069	0.931
M23.3 Other meniscus derangements	0.069	0.931
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.069	0.931
N99-N99 Other disorders of the genitourinary system	0.069	0.931
J45 Asthma	0.069	0.931
M50-M54 Other dorsopathies	0.068	0.931
J39 Other diseases of upper respiratory tract	0.068	0.931
J37 Chronic laryngitis and laryngotracheitis	0.068	0.931
J36 Peritonsillar abscess	0.068	0.931
I69 Sequelae of cerebrovascular disease	0.068	0.932
J30 Vasomotor and allergic rhinitis	0.068	0.932
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.068	0.932
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.068	0.932
T79-T79 Certain early complications of trauma	0.068	0.932
T66-T78 Other and unspecified effects of external causes	0.068	0.932
T33-T35 Frostbite	0.068	0.932
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.068	0.932
T26-T28 Burns and corrosions confined to eye and internal organs	0.068	0.932
T20-T25 Burns and corrosions of external body surface, specified by site	0.068	0.932
T15-T19 Effects of foreign body entering through natural orifice	0.068	0.932
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.068	0.932
T00-T07 Injuries involving multiple body regions	0.068	0.932
S90-S99 Injuries to the ankle and foot	0.068	0.932
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.068	0.932
S10-S19 Injuries to the neck	0.068	0.932
B95-B98 Bacterial, viral and other infectious agents	0.068	0.932
L50-L54 Urticaria and erythema	0.068	0.932
L10-L14 Bullous disorders	0.068	0.932
L00-L08 Infections of the skin and subcutaneous tissue	0.068	0.932
N47 Redundant prepuce, phimosis and paraphimosis	0.068	0.932
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.067	0.932
M19.98 Arthrosis, unspecified (Other)	0.067	0.932
M19.96 Arthrosis, unspecified-Lower leg	0.067	0.932
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.067	0.932
M19.93 Arthrosis, unspecified (Forearm)	0.067	0.932
M19.92 Arthrosis, unspecified (Upper arm)	0.067	0.932
M19.90 Arthrosis, unspecified (Multiple sites)	0.067	0.932
S00-S09 Injuries to the head	0.067	0.933
S82 Fracture of lower leg, including ankle	0.067	0.933
J90 Pleural effusion, not elsewhere classified	0.067	0.933
H36 Retinal disorders in diseases classified elsewhere	0.067	0.933
J95-J99 Other diseases of the respiratory system	0.067	0.933
I05-I09 Chronic rheumatic heart diseases	0.067	0.933
I00-I02 Acute rheumatic fever	0.067	0.933
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.067	0.933
H60-H62 Diseases of external ear	0.067	0.933
S50-S59 Injuries to the elbow and forearm	0.067	0.933
H18 Other disorders of cornea	0.067	0.933
H34 Retinal vascular occlusions	0.067	0.933
H32 Chorioretinal disorders in diseases classified elsewhere	0.067	0.933
H31 Other disorders of choroid	0.067	0.933
H30 Chorioretinal inflammation	0.067	0.933
J69 Pneumonitis due to solids and liquids	0.067	0.933
S70-S79 Injuries to the hip and thigh	0.067	0.933
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.067	0.933
J34 Other disorders of nose and nasal sinuses	0.066	0.934
M23.9 Internal derangement of knee, unspecified	0.066	0.934
M23.6 Other spontaneous disruption of ligament(s) of knee	0.066	0.934
M23.5 Chronic instability of knee	0.066	0.934
M23.1 Discoid meniscus (congenital)	0.066	0.934
M23.0 Cystic meniscus	0.066	0.934
S40-S49 Injuries to the shoulder and upper arm	0.066	0.934
I80 Phlebitis and thrombophlebitis	0.066	0.934
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.066	0.934
F00-F09 Organic, including symptomatic, mental disorders	0.066	0.934
M65 Synovitis and tenosynovitis	0.065	0.934
N41 Inflammatory diseases of prostate	0.066	0.934
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.066	0.934
B35-B49 Mycoses	0.065	0.935
N40 Hyperplasia of prostate	0.065	0.935
E87 Other disorders of fluid, electrolyte and acid-base balance	0.065	0.935
L81 Other disorders of pigmentation	0.065	0.935
L91.8 Other hypertrophic disorders of skin	0.065	0.935
L90.5 Scar conditions and fibrosis of skin	0.065	0.935
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.065	0.935
H04.2 Epiphora	0.065	0.935
N63 Unspecified lump in breast	0.065	0.935
H65-H75 Diseases of middle ear and mastoid	0.065	0.935
H33.2 Serous retinal detachment	0.065	0.935
Chapter XV Pregnancy, childbirth and the puerperium	0.065	0.935
H01 Other inflammation of eyelid	0.064	0.936
J84 Other interstitial pulmonary diseases	0.064	0.936
H40-H42 Glaucoma	0.064	0.936
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.064	0.936
I67.9 Cerebrovascular disease, unspecified	0.064	0.936
N42 Other disorders of prostate	0.064	0.936
L60-L75 Disorders of skin appendages	0.064	0.936
F41 Other anxiety disorders	0.064	0.936
H80-H83 Diseases of inner ear	0.063	0.937
N25-N29 Other disorders of kidney and ureter	0.063	0.937
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.063	0.937
L95 Vasculitis limited to skin, not elsewhere classified	0.063	0.937
L94 Other localised connective tissue disorders	0.063	0.937
L93 Lupus erythematosus	0.063	0.937
L92 Granulomatous disorders of skin and subcutaneous tissue	0.063	0.937
L89 Decubitus ulcer	0.063	0.937
L87 Transepidermal elimination disorders	0.063	0.937
L85 Other epidermal thickening	0.063	0.937
L88 Pyoderma gangrenosum	0.063	0.937
L86 Keratoderma in diseases classified elsewhere	0.063	0.937
L84 Corns and callosities	0.063	0.937
L83 Acanthosis nigricans	0.063	0.937
L80 Vitiligo	0.063	0.937
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.063	0.937
J44 Other chronic obstructive pulmonary disease	0.063	0.937
I73 Other peripheral vascular diseases	0.063	0.937
J43 Emphysema	0.063	0.937
E83 Disorders of mineral metabolism	0.063	0.937
J70 Respiratory conditions due to other external agents	0.063	0.937
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.063	0.937
J67 Hypersensitivity pneumonitis due to organic dust	0.063	0.937
J66 Airway disease due to specific organic dust	0.063	0.937
J63 Pneumoconiosis due to other inorganic dusts	0.063	0.937
J62 Pneumoconiosis due to dust containing silica	0.063	0.937
J65 Pneumoconiosis associated with tuberculosis	0.063	0.937
J64 Unspecified pneumoconiosis	0.063	0.937
J60 Coalworker's pneumoconiosis	0.063	0.937
E86 Volume depletion	0.063	0.937
N17.9 Acute renal failure, unspecified	0.063	0.937
H00 Hordeolum and chalazion	0.062	0.937
I68 Cerebrovascular disorders in diseases classified elsewhere	0.062	0.937
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.062	0.937
I62 Other nontraumatic intracranial haemorrhage	0.062	0.937
I61 Intracerebral haemorrhage	0.062	0.937
I60 Subarachnoid haemorrhage	0.062	0.937
B25-B34 Other viral diseases	0.062	0.937
N60 Benign mammary dysplasia	0.062	0.938
I95-I99 Other and unspecified disorders of the circulatory system	0.062	0.938
I74 Arterial embolism and thrombosis	0.062	0.938
N30-N39 Other diseases of urinary system	0.062	0.938
J32.9 Chronic sinusitis, unspecified	0.062	0.938
L40-L45 Papulosquamous disorders	0.062	0.938
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.062	0.938
H05 Disorders of orbit	0.062	0.938
H03 Disorders of eyelid in diseases classified elsewhere	0.062	0.938
M67 Other disorders of synovium and tendon	0.062	0.938
B99-B99 Other infectious diseases	0.062	0.938
B90-B94 Sequelae of infectious and parasitic diseases	0.062	0.938
B85-B89 Pediculosis, acariasis and other infestations	0.062	0.938
B65-B83 Helminthiases	0.062	0.938
B50-B64 Protozoal diseases	0.062	0.938
B20-B24 Human immunodeficiency virus [HIV] disease	0.062	0.938
B15-B19 Viral hepatitis	0.062	0.938
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.062	0.938
A80-A89 Viral infections of the central nervous system	0.062	0.938
A75-A79 Rickettsioses	0.062	0.938
A70-A74 Other diseases caused by chlamydiae	0.062	0.938
A65-A69 Other spirochaetal diseases	0.062	0.938
A50-A64 Infections with a predominantly sexual mode of transmission	0.062	0.938
A20-A28 Certain zoonotic bacterial diseases	0.062	0.938
A15-A19 Tuberculosis	0.062	0.938
H35.9 Retinal disorder, unspecified	0.061	0.938
H35.7 Separation of retinal layers	0.061	0.938
H35.6 Retinal haemorrhage	0.061	0.938
H35.5 Hereditary retinal dystrophy	0.061	0.938
H35.4 Peripheral retinal degeneration	0.061	0.938
H35.2 Other proliferative retinopathy	0.061	0.938
H35.1 Retinopathy of prematurity	0.061	0.938
H35.0 Background retinopathy and retinal vascular changes	0.061	0.938
F99-F99 Unspecified mental disorder	0.061	0.939
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.061	0.939
F80-F89 Disorders of psychological development	0.061	0.939
F70-F79 Mental retardation	0.061	0.939
F60-F69 Disorders of adult personality and behaviour	0.061	0.939
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.061	0.939
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.061	0.939
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.061	0.939
I88 Nonspecific lymphadenitis	0.061	0.939
I87 Other disorders of veins	0.061	0.939
I86 Varicose veins of other sites	0.061	0.939
I85 Oesophageal varices	0.061	0.939
I82 Other venous embolism and thrombosis	0.061	0.939
I81 Portal vein thrombosis	0.061	0.939
E50-E64 Other nutritional deficiencies	0.061	0.939
A30-A49 Other bacterial diseases	0.061	0.939
N43 Hydrocele and spermatocele	0.061	0.939
M19.09 Primary arthrosis of other joints (Site unspecified)	0.061	0.939
M19.08 Primary arthrosis of other joints (Other)	0.061	0.939
M19.06 Primary arthrosis of other joints-Lower leg	0.061	0.939
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.061	0.939
M19.04 Primary arthrosis of other joints (Hand)	0.061	0.939
M19.03 Primary arthrosis of other joints (Forearm)	0.061	0.939
M19.02 Primary arthrosis of other joints (Upper arm)	0.061	0.939
M19.01 Primary arthrosis of other joints (Shoulder region)	0.061	0.939
M19.00 Primary arthrosis of other joints (Multiple sites)	0.061	0.939
M23.49 Loose body in knee-Unspec lig/men	0.061	0.939
J38.3 Other diseases of vocal cords	0.061	0.939
J33 Nasal polyp	0.061	0.939
J41 Simple and mucopurulent chronic bronchitis	0.060	0.939
J46 Status asthmaticus	0.060	0.939
J42 Unspecified chronic bronchitis	0.060	0.939
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.060	0.939
M66 Spontaneous rupture of synovium and tendon	0.060	0.939
J18 Pneumonia, organism unspecified	0.060	0.940
J40 Bronchitis, not specified as acute or chronic	0.060	0.940
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.060	0.940
I83.1 Varicose veins of lower extremities with inflammation	0.060	0.940
I83.0 Varicose veins of lower extremities with ulcer	0.060	0.940
M25.7 Osteophyte	0.060	0.940
J94 Other pleural conditions	0.060	0.940
J93 Pneumothorax	0.060	0.940
J92 Pleural plaque	0.060	0.940
J91 Pleural effusion in conditions classified elsewhere	0.060	0.940
N51 Disorders of male genital organs in diseases classified elsewhere	0.059	0.940
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.059	0.940
N48 Other disorders of penis	0.059	0.940
N46 Male infertility	0.059	0.940
N44 Torsion of testis	0.059	0.940
H91 Other hearing loss	0.059	0.940
M16 Coxarthrosis [arthrosis of hip]	0.059	0.940
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.059	0.940
S68 Traumatic amputation of wrist and hand	0.059	0.941
S22 Fracture of rib(s), sternum and thoracic spine	0.059	0.941
A00-A09 Intestinal infectious diseases	0.059	0.941
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.059	0.941
J35.8 Other chronic diseases of tonsils and adenoids	0.059	0.941
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.059	0.941
J35.2 Hypertrophy of adenoids	0.059	0.941
J35.0 Chronic tonsillitis	0.059	0.941
J38.7 Other diseases of larynx	0.059	0.941
J38.6 Stenosis of larynx	0.059	0.941
J38.5 Laryngeal spasm	0.059	0.941
J38.4 Oedema of larynx	0.059	0.941
J38.2 Nodules of vocal cords	0.059	0.941
J38.1 Polyp of vocal cord and larynx	0.059	0.941
I77 Other disorders of arteries and arterioles	0.059	0.941
S64 Injury of nerves at wrist and hand level	0.059	0.941
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.058	0.941
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.058	0.942
H21 Other disorders of iris and ciliary body	0.058	0.942
H20 Iridocyclitis	0.058	0.942
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.058	0.942
H17 Corneal scars and opacities	0.058	0.942
H16 Keratitis	0.058	0.942
H15 Disorders of sclera	0.058	0.942
J82 Pulmonary eosinophilia, not elsewhere classified	0.058	0.942
J81 Pulmonary oedema	0.058	0.942
J80 Adult respiratory distress syndrome	0.058	0.942
S62 Fracture at wrist and hand level	0.058	0.942
M06 Other rheumatoid arthritis	0.058	0.942
M43 Other deforming dorsopathies	0.058	0.942
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.058	0.942
I63.8 Other cerebral infarction	0.058	0.942
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.058	0.942
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.058	0.942
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.058	0.942
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.058	0.942
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.058	0.942
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.058	0.942
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.058	0.942
H26 Other cataract	0.058	0.942
E87.7 Fluid overload	0.058	0.942
E40-E46 Malnutrition	0.057	0.942
E20-E35 Disorders of other endocrine glands	0.057	0.942
J45.9 Asthma, unspecified	0.058	0.942
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.058	0.942
M20.6 Acquired deformity of toe(s), unspecified	0.057	0.943
N70-N77 Inflammatory diseases of female pelvic organs	0.057	0.943
N18.9 Chronic renal failure, unspecified	0.057	0.943
M42 Spinal osteochondrosis	0.057	0.943
M41 Scoliosis	0.057	0.943
M40 Kyphosis and lordosis	0.057	0.943
N64 Other disorders of breast	0.057	0.943
N61 Inflammatory disorders of breast	0.057	0.943
N45 Orchitis and epididymitis	0.057	0.943
S89 Other and unspecified injuries of lower leg	0.057	0.943
S88 Traumatic amputation of lower leg	0.057	0.943
S87 Crushing injury of lower leg	0.057	0.943
S86 Injury of muscle and tendon at lower leg level	0.057	0.943
S85 Injury of blood vessels at lower leg level	0.057	0.943
S84 Injury of nerves at lower leg level	0.057	0.943
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.057	0.943
S81 Open wound of lower leg	0.057	0.943
S80 Superficial injury of lower leg	0.057	0.943
H18.5 Hereditary corneal dystrophies	0.057	0.943
M75 Shoulder lesions	0.057	0.943
J17 Pneumonia in diseases classified elsewhere	0.057	0.943
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.057	0.943
J15 Bacterial pneumonia, not elsewhere classified	0.057	0.943
J12 Viral pneumonia, not elsewhere classified	0.057	0.943
J11 Influenza, virus not identified	0.057	0.943
J10 Influenza due to identified influenza virus	0.057	0.943
J14 Pneumonia due to Haemophilus influenzae	0.057	0.943
J13 Pneumonia due to Streptococcus pneumoniae	0.057	0.943
J09 Influenza due to certain identified influenza virus	0.057	0.943
T85 Complications of other internal prosthetic devices, implants and grafts	0.057	0.943
H53 Visual disturbances	0.057	0.943
J47 Bronchiectasis	0.057	0.943
F30-F39 Mood [affective] disorders	0.057	0.943
H04.9 Disorder of lachrymal system, unspecified	0.056	0.943
H04.8 Other disorders of lachrymal system	0.056	0.943
H04.6 Other changes in lachrymal passages	0.056	0.943
H04.4 Chronic inflammation of lachrymal passages	0.056	0.943
H04.3 Acute and unspecified inflammation of lachrymal passages	0.056	0.943
H04.1 Other disorders of lachrymal gland	0.056	0.943
H04.0 Dacryoadenitis	0.056	0.943
Y95 Nosocomial condition	0.056	0.943
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.056	0.943
I72 Other aneurysm	0.056	0.943
I70 Atherosclerosis	0.056	0.943
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.056	0.943
I78 Diseases of capillaries	0.056	0.943
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.056	0.944
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.056	0.944
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.056	0.944
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.056	0.944
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.056	0.944
F41.9 Anxiety disorder, unspecified	0.056	0.944
N18.3 Chronic kidney disease, stage 3	0.056	0.944
N20 Calculus of kidney and ureter	0.056	0.944
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.056	0.944
M02 Reactive arthropathies	0.056	0.944
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.056	0.944
M00 Pyogenic arthritis	0.056	0.944
M63 Disorders of muscle in diseases classified elsewhere	0.056	0.944
M62 Other disorders of muscle	0.056	0.944
M61 Calcification and ossification of muscle	0.056	0.944
M60 Myositis	0.056	0.944
M90 Osteopathies in diseases classified elsewhere	0.056	0.944
M89 Other disorders of bone	0.056	0.944
M88 Paget's disease of bone [osteitis deformans]	0.056	0.944
M87 Osteonecrosis	0.056	0.944
M86 Osteomyelitis	0.056	0.944
M94 Other disorders of cartilage	0.056	0.944
M93 Other osteochondropathies	0.056	0.944
M92 Other juvenile osteochondrosis	0.056	0.944
M91 Juvenile osteochondrosis of hip and pelvis	0.056	0.944
M99 Biomechanical lesions, not elsewhere classified	0.056	0.944
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.056	0.944
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.056	0.944
M15.9 Polyarthrosis, unspecified	0.056	0.944
M15.0 Primary generalised (osteo)arthrosis	0.056	0.944
M15.8 Other polyarthrosis	0.056	0.944
M15.4 Erosive (osteo)arthrosis	0.056	0.944
M15.3 Secondary multiple arthrosis	0.056	0.944
M15.2 Bouchard's nodes (with arthropathy)	0.056	0.944
M15.1 Heberden's nodes (with arthropathy)	0.056	0.944
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.056	0.944
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.056	0.944
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.055	0.944
Y60-Y69 Misadventures to patients during surgical and medical care	0.055	0.944
Y35-Y36 Legal intervention and operations of war	0.055	0.944
Y10-Y34 Event of undetermined intent	0.055	0.944
Y00-Y09 Assault	0.055	0.944
X85-X99 Assault	0.055	0.944
X60-X84 Intentional self-harm	0.055	0.944
X58-X59 Accidental exposure to other and unspecified factors	0.055	0.944
X50-X57 Overexertion, travel and privation	0.055	0.944
X40-X49 Accidental poisoning by and exposure to noxious substances	0.055	0.944
X30-X39 Exposure to forces of nature	0.055	0.944
X20-X29 Contact with venomous animals and plants	0.055	0.944
X10-X19 Contact with heat and hot substances	0.055	0.944
X00-X09 Exposure to smoke, fire and flames	0.055	0.944
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.055	0.944
W75-W84 Other accidental threats to breathing	0.055	0.944
W65-W74 Accidental drowning and submersion	0.055	0.944
W50-W64 Exposure to animate mechanical forces	0.055	0.944
W20-W49 Exposure to inanimate mechanical forces	0.055	0.944
V98-V99 Other and unspecified transport accidents	0.055	0.944
V95-V97 Air and space transport accidents	0.055	0.944
V90-V94 Water transport accidents	0.055	0.944
V80-V89 Other land transport accidents	0.055	0.944
V70-V79 Bus occupant injured in transport accident	0.055	0.944
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.055	0.944
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.055	0.944
V40-V49 Car occupant injured in transport accident	0.055	0.944
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.055	0.944
V20-V29 Motorcycle rider injured in transport accident	0.055	0.944
V10-V19 Pedal cyclist injured in transport accident	0.055	0.944
V01-V09 Pedestrian injured in transport accident	0.055	0.944
H43 Disorders of vitreous body	0.055	0.945
P90-P96 Other disorders originating in the perinatal period	0.055	0.945
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.055	0.945

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations