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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1265181
log Bayes Factor = 324.743
Chromosome 6   position 31,155,785  (GRCh37) Explore rs1265181 on Ensembl!
Variant rs1265181 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
1.000 0.000 0.000
L40-L45 Papulosquamous disorders
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
M07.3 Other psoriatic arthropathies
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
D80-D89 Certain disorders involving the immune mechanism
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
B35-B49 Mycoses
0.999 0.001 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.999 0.001 0.000
B37 Candidiasis
0.999 0.001 0.000
E11.9 Without complications
0.998 0.002 0.000
D86 Sarcoidosis
0.998 0.002 0.000
K72 Hepatic failure, not elsewhere classified
0.997 0.003 0.000
K75.4 Autoimmune hepatitis
0.997 0.003 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.997 0.003 0.000
C83.3 Large cell (diffuse)
0.996 0.004 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.995 0.005 0.000
E10.1 With ketoacidosis
0.995 0.005 0.000
L40.0 Psoriasis vulgaris
0.995 0.005 0.000
E14.3 With ophthalmic complications
0.993 0.007 0.000
D50-D53 Nutritional anaemias
0.993 0.007 0.000
D70 Agranulocytosis
0.993 0.007 0.000
E20-E35 Disorders of other endocrine glands
0.993 0.007 0.000
C85.1 B-cell lymphoma, unspecified
0.992 0.008 0.000
B37.9 Candidiasis, unspecified
0.989 0.011 0.000
E70-E90 Metabolic disorders
0.988 0.012 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.988 0.012 0.000
K74 Fibrosis and cirrhosis of liver
0.987 0.013 0.000
E27 Other disorders of adrenal gland
0.987 0.013 0.000
D86.9 Sarcoidosis, unspecified
0.986 0.014 0.000
E27.1 Primary adrenocortical insufficiency
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.985 0.015 0.000
B37.0 Candidal stomatitis
0.985 0.015 0.000
D50 Iron deficiency anaemia
0.985 0.015 0.000
K72.9 Hepatic failure, unspecified
0.985 0.015 0.000
K75.8 Other specified inflammatory liver diseases
0.983 0.017 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.981 0.019 0.000
E11.3 With ophthalmic complications
0.981 0.019 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.979 0.021 0.000
G56.0 Carpal tunnel syndrome
0.979 0.021 0.000
Chapter VI Diseases of the nervous system
0.979 0.021 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.979 0.021 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.978 0.022 0.000
G56 Mononeuropathies of upper limb
0.976 0.024 0.000
D50.9 Iron deficiency anaemia, unspecified
0.975 0.025 0.000
E11.1 With ketoacidosis
0.972 0.028 0.000
K50-K52 Noninfective enteritis and colitis
0.972 0.028 0.000
K52 Other non-infective gastro-enteritis and colitis
0.970 0.030 0.000
M07 Psoriatic and enteropathic arthropathies
0.970 0.030 0.000
H36.0 Diabetic retinopathy
0.968 0.032 0.000
E14.9 Without complications
0.966 0.034 0.000
Chapter VII Diseases of the eye and adnexa
0.964 0.036 0.000
K73 Chronic hepatitis, not elsewhere classified
0.964 0.036 0.000
K74.6 Other and unspecified cirrhosis of liver
0.963 0.037 0.000
H36 Retinal disorders in diseases classified elsewhere
0.963 0.037 0.000
Chapter XIV Diseases of the genitourinary system
0.961 0.039 0.000
D61 Other aplastic anaemias
0.961 0.039 0.000
L10-L14 Bullous disorders
0.961 0.039 0.000
B15-B19 Viral hepatitis
0.960 0.040 0.000
H30-H36 Disorders of choroid and retina
0.960 0.040 0.000
E10.2 With renal complications
0.960 0.040 0.000
N13 Obstructive and reflux uropathy
0.959 0.041 0.000
N00-N08 Glomerular diseases
0.958 0.042 0.000
N10-N16 Renal tubulo-interstitial diseases
0.958 0.042 0.000
G51 Facial nerve disorders
0.957 0.043 0.000
E78.5 Hyperlipidaemia, unspecified
0.956 0.044 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.956 0.044 0.000
D55-D59 Haemolytic anaemias
0.954 0.046 0.000
D86.0 Sarcoidosis of lung
0.953 0.047 0.000
Chapter II Neoplasms
0.953 0.047 0.000
E78.2 Mixed hyperlipidaemia
0.951 0.049 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.951 0.049 0.000
M05-M14 Inflammatory polyarthropathies
0.948 0.052 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.947 0.053 0.000
K72.0 Acute and subacute hepatic failure
0.947 0.053 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.942 0.058 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.939 0.061 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.939 0.061 0.000
L13 Other bullous disorders
0.938 0.062 0.000
N04 Nephrotic syndrome
0.937 0.063 0.000
K76 Other diseases of liver
0.936 0.064 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.934 0.066 0.000
B02 Zoster [herpes zoster]
0.932 0.068 0.000
H46 Optic neuritis
0.930 0.070 0.000
D59 Acquired haemolytic anaemia
0.930 0.070 0.000
K90.9 Intestinal malabsorption, unspecified
0.929 0.071 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.929 0.071 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.926 0.074 0.000
D61.9 Aplastic anaemia, unspecified
0.924 0.076 0.000
N17-N19 Renal failure
0.924 0.076 0.000
L13.0 Dermatitis herpetiformis
0.922 0.078 0.000
W00-W19 Falls
0.922 0.078 0.000
E88 Other metabolic disorders
0.919 0.081 0.000
E89.0 Postprocedural hypothyroidism
0.918 0.082 0.000
N04.9 Unspecified
0.917 0.083 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.915 0.085 0.000
W19 Unspecified fall
0.914 0.086 0.000
B00 Herpesviral [herpes simplex] infections
0.912 0.088 0.000
G51.0 Bell's palsy
0.909 0.091 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.908 0.092 0.000
B02.9 Zoster without complication
0.907 0.093 0.000
G30-G32 Other degenerative diseases of the nervous system
0.907 0.093 0.000
E50-E64 Other nutritional deficiencies
0.905 0.095 0.000
N18 Chronic renal failure
0.905 0.095 0.000
E06 Thyroiditis
0.904 0.096 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.904 0.096 0.000
V40-V49 Car occupant injured in transport accident
0.904 0.096 0.000
E24 Cushing's syndrome
0.903 0.097 0.000
M20-M25 Other joint disorders
0.902 0.098 0.000
B18 Chronic viral hepatitis
0.902 0.098 0.000
C34 Malignant neoplasm of bronchus and lung
0.900 0.100 0.000
M35.0 Sicca syndrome [Sjogren]
0.900 0.100 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.899 0.101 0.000
A15-A19 Tuberculosis
0.898 0.102 0.000
M35 Other systemic involvement of connective tissue
0.897 0.103 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.895 0.105 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.895 0.105 0.000
K83 Other diseases of biliary tract
0.894 0.106 0.000
Y43 Primarily systemic agents
0.891 0.109 0.000
K80 Cholelithiasis
0.890 0.110 0.000
N11 Chronic tubulo-interstitial nephritis
0.889 0.111 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.888 0.112 0.000
K76.9 Liver disease, unspecified
0.887 0.113 0.000
N05 Unspecified nephritic syndrome
0.887 0.113 0.000
E10.8 With unspecified complications
0.884 0.116 0.000
K83.0 Cholangitis
0.884 0.116 0.000
D59.1 Other autoimmune haemolytic anaemias
0.883 0.117 0.000
W19.9 Unspecified place
0.882 0.118 0.000
L20-L30 Dermatitis and eczema
0.878 0.122 0.000
K74.0 Hepatic fibrosis
0.877 0.123 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.875 0.125 0.000
D50.8 Other iron deficiency anaemias
0.875 0.125 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.873 0.127 0.000
L28 Lichen simplex chronicus and prurigo
0.871 0.129 0.000
H53-H54 Visual disturbances and blindness
0.866 0.134 0.000
B01 Varicella [chickenpox]
0.866 0.134 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.866 0.134 0.000
W19.3 Sports and athletics area
0.865 0.135 0.000
C91 Lymphoid leukaemia
0.864 0.136 0.000
L28.0 Lichen simplex chronicus
0.863 0.137 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.861 0.139 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.860 0.140 0.000
B17 Other acute viral hepatitis
0.857 0.143 0.000
D86.3 Sarcoidosis of skin
0.857 0.143 0.000
L40.1 Generalised pustular psoriasis
0.856 0.144 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.855 0.145 0.000
E03.8 Other specified hypothyroidism
0.855 0.145 0.000
E78.8 Other disorders of lipoprotein metabolism
0.854 0.146 0.000
G51.9 Disorder of facial nerve, unspecified
0.853 0.147 0.000
N18.9 Chronic renal failure, unspecified
0.853 0.147 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.853 0.147 0.000
D62 Acute posthaemorrhagic anaemia
0.850 0.150 0.000
Y43.3 Other antineoplastic drugs
0.849 0.151 0.000
L50-L54 Urticaria and erythema
0.849 0.151 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.848 0.152 0.000
C84.5 Other and unspecified T-cell lymphomas
0.844 0.156 0.000
K73.9 Chronic hepatitis, unspecified
0.841 0.159 0.000
N13.6 Pyonephrosis
0.838 0.162 0.000
D51 Vitamin B12 deficiency anaemia
0.838 0.162 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.837 0.163 0.000
D80 Immunodeficiency with predominantly antibody defects
0.836 0.164 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.834 0.166 0.000
H30 Chorioretinal inflammation
0.831 0.169 0.000
H47.3 Other disorders of optic disk
0.830 0.170 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.830 0.170 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.830 0.170 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.829 0.171 0.000
B25-B34 Other viral diseases
0.829 0.171 0.000
N18.3 Chronic kidney disease, stage 3
0.829 0.171 0.000
G51.3 Clonic hemifacial spasm
0.829 0.171 0.000
E55 Vitamin D deficiency
0.828 0.171 0.000
D83 Common variable immunodeficiency
0.828 0.172 0.000
N05.2 Diffuse membranous glomerulonephritis
0.826 0.174 0.000
X60-X84 Intentional self-harm
0.826 0.174 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.824 0.176 0.000
B18.2 Chronic viral hepatitis C
0.824 0.176 0.000
E06.3 Autoimmune thyroiditis
0.820 0.180 0.000
M24 Other specific joint derangements
0.818 0.182 0.000
Y52 Agents primarily affecting the cardiovascular system
0.817 0.183 0.000
L44 Other papulosquamous disorders
0.817 0.183 0.000
C81 Hodgkin's disease
0.817 0.183 0.000
E24.0 Pituitary-dependent Cushing's disease
0.816 0.184 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.816 0.184 0.000
A63.0 Anogenital (venereal) warts
0.816 0.184 0.000
E14.8 With unspecified complications
0.814 0.186 0.000
A30-A49 Other bacterial diseases
0.814 0.186 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.812 0.188 0.000
E13 Other specified diabetes mellitus
0.807 0.193 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.806 0.194 0.000
C88 Malignant immunoproliferative diseases
0.806 0.194 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.806 0.194 0.000
K76.6 Portal hypertension
0.805 0.195 0.000
A41.9 Septicaemia, unspecified
0.805 0.195 0.000
E78.4 Other hyperlipidaemia
0.805 0.195 0.000
E25 Adrenogenital disorders
0.804 0.196 0.000
E40-E46 Malnutrition
0.804 0.196 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.804 0.196 0.000
B00.5 Herpesviral ocular disease
0.804 0.196 0.000
H53 Visual disturbances
0.803 0.197 0.000
D86.1 Sarcoidosis of lymph nodes
0.803 0.197 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.802 0.197 0.000
V01-V09 Pedestrian injured in transport accident
0.802 0.198 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.802 0.198 0.000
E10.7 With multiple complications
0.801 0.199 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.801 0.199 0.000
A41 Other septicaemia
0.799 0.201 0.000
C91.1 Chronic lymphocytic leukaemia
0.799 0.201 0.000
D72 Other disorders of white blood cells
0.797 0.203 0.000
Q60-Q64 Congenital malformations of the urinary system
0.796 0.204 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.794 0.206 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.794 0.206 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.793 0.207 0.000
G31.8 Other specified degenerative diseases of nervous system
0.793 0.207 0.000
C34.9 Bronchus or lung, unspecified
0.793 0.207 0.000
D69 Purpura and other haemorrhagic conditions
0.792 0.208 0.000
N17 Acute renal failure
0.792 0.208 0.000
E14.2 Withrenal complications
0.792 0.208 0.000
E23 Hypofunction and other disorders of pituitary gland
0.791 0.209 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.790 0.210 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.790 0.210 0.000
L40.4 Guttate psoriasis
0.790 0.210 0.000
C34.3 Lower lobe, bronchus or lung
0.790 0.210 0.000
E78.6 Lipoprotein deficiency
0.789 0.211 0.000
E11.6 With other specified complications
0.787 0.213 0.000
B37.8 Candidiasis of other sites
0.787 0.213 0.000
A20-A28 Certain zoonotic bacterial diseases
0.786 0.214 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.786 0.214 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.785 0.215 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.784 0.216 0.000
M35.7 Hypermobility syndrome
0.784 0.216 0.000
B17.1 Acute hepatitis C
0.783 0.217 0.000
C83.0 Small cell (diffuse)
0.781 0.219 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.781 0.219 0.000
C34.2 Middle lobe, bronchus or lung
0.780 0.220 0.000
B01.9 Varicella without complications
0.779 0.221 0.000
B37.7 Candidal septicaemia
0.779 0.221 0.000
K52.3 Indeterminate colitis
0.778 0.222 0.000
K76.7 Hepatorenal syndrome
0.777 0.223 0.000
E88.8 Other specified metabolic disorders
0.777 0.223 0.000
D53 Other nutritional anaemias
0.775 0.225 0.000
G56.4 Causalgia
0.774 0.226 0.000
E55.9 Vitamin D deficiency, unspecified
0.774 0.226 0.000
B00.9 Herpesviral infection, unspecified
0.774 0.226 0.000
D64.8 Other specified anaemias
0.773 0.227 0.000
W50-W64 Exposure to animate mechanical forces
0.772 0.228 0.000
H47.2 Optic atrophy
0.772 0.228 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.772 0.228 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.772 0.228 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.771 0.229 0.000
E31 Polyglandular dysfunction
0.770 0.230 0.000
E14.5 With peripheral circulatory complications
0.769 0.231 0.000
V48 Car occupant injured in noncollision transport accident
0.768 0.232 0.000
D50.1 Sideropenic dysphagia
0.768 0.232 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.767 0.233 0.000
W18 Other fall on same level
0.766 0.234 0.000
Y42.7 Androgens and anabolic congeners
0.766 0.234 0.000
K71 Toxic liver disease
0.765 0.235 0.000
G35 Multiple sclerosis
0.765 0.235 0.000
W19.6 Industrial and construction area
0.765 0.235 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.763 0.237 0.000
W05 Fall involving wheelchair
0.763 0.237 0.000
M33 Dermatopolymyositis
0.762 0.238 0.000
M11 Other crystal arthropathies
0.762 0.238 0.000
D61.1 Drug-induced aplastic anaemia
0.762 0.238 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.761 0.239 0.000
K72.1 Chronic hepatic failure
0.760 0.240 0.000
A65-A69 Other spirochaetal diseases
0.760 0.240 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.760 0.240 0.000
H53.1 Subjective visual disturbances
0.759 0.241 0.000
E10.4 With neurological complications
0.759 0.241 0.000
G31.0 Circumscribed brain atrophy
0.758 0.242 0.000
B37.4 Candidiasis of other urogenital sites
0.758 0.242 0.000
X58 Exposure to other specified factors
0.757 0.243 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.757 0.243 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.755 0.245 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.755 0.245 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.754 0.246 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.754 0.246 0.000
M10 Gout
0.754 0.246 0.000
E89.2 Postprocedural hypoparathyroidism
0.754 0.246 0.000
X10-X19 Contact with heat and hot substances
0.752 0.248 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.751 0.249 0.000
W14 Fall from tree
0.750 0.250 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.750 0.250 0.000
E14.1 With ketoacidosis
0.748 0.251 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.748 0.252 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.748 0.252 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.747 0.253 0.000
E14.6 With other specified complications
0.747 0.253 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.747 0.253 0.000
N13.8 Other obstructive and reflux uropathy
0.747 0.253 0.000
B16 Acute hepatitis B
0.747 0.253 0.000
L53 Other erythematous conditions
0.746 0.254 0.000
E53 Deficiency of other B group vitamins
0.746 0.254 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.745 0.254 0.000
E24.2 Drug-induced Cushing's syndrome
0.744 0.256 0.000
B36 Other superficial mycoses
0.741 0.259 0.000
B37.2 Candidiasis of skin and nail
0.741 0.259 0.000
K74.3 Primary biliary cirrhosis
0.741 0.259 0.000
Y59 Other and unspecified vaccines and biological substances
0.740 0.260 0.000
Y54.8 Agents affecting uric acid metabolism
0.739 0.261 0.000
H30.9 Chorioretinal inflammation, unspecified
0.739 0.261 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.738 0.261 0.000
Y54.4 Loop [high-ceiling] diuretics
0.738 0.262 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.737 0.263 0.000
B25 Cytomegaloviral disease
0.736 0.263 0.000
C34.0 Main bronchus
0.736 0.264 0.000
A17 Tuberculosis of nervous system
0.735 0.265 0.000
N04.2 Diffuse membranous glomerulonephritis
0.734 0.266 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.734 0.266 0.000
E16.1 Other hypoglycaemia
0.733 0.266 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.733 0.267 0.000
E10.6 With other specified complications
0.733 0.267 0.000
B44 Aspergillosis
0.733 0.267 0.000
L40.8 Other psoriasis
0.732 0.268 0.000
B65-B83 Helminthiases
0.730 0.270 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.730 0.270 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.729 0.271 0.000
B07 Viral warts
0.729 0.271 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.727 0.273 0.000
G56.1 Other lesions of median nerve
0.726 0.274 0.000
C31 Malignant neoplasm of accessory sinuses
0.725 0.275 0.000
Y10-Y34 Event of undetermined intent
0.722 0.277 0.000
N18.0 End-stage renal disease
0.722 0.278 0.000
M34 Systemic sclerosis
0.722 0.278 0.000
K83.5 Biliary cyst
0.721 0.279 0.000
M24.6 Ankylosis of joint
0.721 0.279 0.000
E11.5 With peripheral circulatory complications
0.720 0.280 0.000
N00 Acute nephritic syndrome
0.720 0.280 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.720 0.280 0.000
V90-V94 Water transport accidents
0.720 0.280 0.000
B37.1 Pulmonary candidiasis
0.719 0.281 0.000
M70-M79 Other soft tissue disorders
0.719 0.281 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
L41 Parapsoriasis
0.717 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.717 0.283 0.000
K75.2 Nonspecific reactive hepatitis
0.717 0.283 0.000
K75.1 Phlebitis of portal vein
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
M07.38 Other psoriatic arthropathies (Other)
0.717 0.283 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.717 0.283 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.717 0.283 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.716 0.283 0.000
C94 Other leukaemias of specified cell type
0.716 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.716 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.283 0.000
E16.3 Increased secretion of glucagon
0.716 0.283 0.000
D82 Immunodeficiency associated with other major defects
0.716 0.283 0.000
D81 Combined immunodeficiencies
0.716 0.283 0.000
B48 Other mycoses, not elsewhere classified
0.716 0.284 0.000
B47 Mycetoma
0.716 0.284 0.000
B46 Zygomycosis
0.716 0.284 0.000
B45 Cryptococcosis
0.716 0.284 0.000
B43 Chromomycosis and phaeomycotic abscess
0.716 0.284 0.000
B42 Sporotrichosis
0.716 0.284 0.000
B41 Paracoccidioidomycosis
0.716 0.284 0.000
B40 Blastomycosis
0.716 0.284 0.000
B39 Histoplasmosis
0.716 0.284 0.000
B38 Coccidioidomycosis
0.716 0.284 0.000
C85.0 Lymphosarcoma
0.716 0.284 0.000
B37.6 Candidal endocarditis
0.716 0.284 0.000
B37.5 Candidal meningitis
0.716 0.284 0.000
Y43.1 Antineoplastic antimetabolites
0.715 0.285 0.000
Q00-Q07 Congenital malformations of the nervous system
0.715 0.285 0.000
C83.6 Undifferentiated (diffuse)
0.715 0.285 0.000
C83.5 Lymphoblastic (diffuse)
0.715 0.285 0.000
C83.4 Immunoblastic (diffuse)
0.715 0.285 0.000
C83.2 Mixed small and large cell (diffuse)
0.715 0.285 0.000
C91.9 Lymphoid leukaemia, unspecified
0.715 0.285 0.000
D74 Methaemoglobinaemia
0.714 0.286 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.714 0.286 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.714 0.286 0.000
D69.4 Other primary thrombocytopenia
0.713 0.287 0.000
K83.3 Fistula of bile duct
0.712 0.287 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
N18.1 Chronic kidney disease, stage 1
0.712 0.288 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.712 0.288 0.000
E32 Diseases of thymus
0.712 0.288 0.000
E30 Disorders of puberty, not elsewhere classified
0.712 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.288 0.000
Y48 Anaesthetics and therapeutic gases
0.711 0.289 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.711 0.289 0.000
W19.2 School, other institution and public administrative area
0.711 0.289 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.711 0.289 0.000
X59 Exposure to unspecified factor
0.710 0.290 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.710 0.290 0.000
M32 Systemic lupus erythematosus
0.710 0.290 0.000
E84 Cystic fibrosis
0.709 0.291 0.000
E77 Disorders of glycoprotein metabolism
0.709 0.291 0.000
E76 Disorders of glycosaminoglycan metabolism
0.709 0.291 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.709 0.291 0.000
E72 Other disorders of amino-acid metabolism
0.709 0.291 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.709 0.291 0.000
E70 Disorders of aromatic amino-acid metabolism
0.709 0.291 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.709 0.291 0.000
B06 Rubella [German measles]
0.708 0.292 0.000
B05 Measles
0.708 0.292 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.708 0.292 0.000
B04 Monkeypox
0.708 0.292 0.000
B03 Smallpox
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
E10.0 With coma
0.708 0.292 0.000
K74.4 Secondary biliary cirrhosis
0.708 0.292 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.708 0.292 0.000
K74.1 Hepatic sclerosis
0.708 0.292 0.000
E88.9 Metabolic disorder, unspecified
0.707 0.293 0.000
E27.5 Adrenomedullary hyperfunction
0.707 0.293 0.000
E27.0 Other adrenocortical overactivity
0.707 0.293 0.000
K75.9 Inflammatory liver disease, unspecified
0.707 0.293 0.000
N11.1 Chronic obstructive pyelonephritis
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
E78.3 Hyperchylomicronaemia
0.706 0.294 0.000
B02.8 Zoster with other complications
0.705 0.295 0.000
C15-C26 Malignant neoplasms of digestive organs
0.705 0.295 0.000
D83.9 Common variable immunodeficiency, unspecified
0.705 0.295 0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis
0.704 0.296 0.000
C34.8 Overlapping lesion of bronchus and lung
0.704 0.296 0.000
W19.1 Residential institution
0.703 0.297 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.703 0.297 0.000
H53.8 Other visual disturbances
0.703 0.297 0.000
E11.2 With renal complications
0.703 0.297 0.000
G70-G73 Diseases of myoneural junction and muscle
0.703 0.297 0.000
E03.1 Congenital hypothyroidism without goitre
0.702 0.297 0.000
E14.4 With neurological complications
0.702 0.298 0.000
D86.8 Sarcoidosis of other and combined sites
0.702 0.298 0.000
L52 Erythema nodosum
0.701 0.299 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.701 0.299 0.000
E51 Thiamine deficiency
0.699 0.301 0.000
D69.2 Other nonthrombocytopenic purpura
0.698 0.302 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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