TreeWAS – Variant ID: rs12661281

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	0.999	0.001	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.999	0.001	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.998	0.002	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.998	0.002	0.000
K51 Ulcerative colitis	0.000	0.004	0.996
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.995	0.005	0.000
M35.3 Polymyalgia rheumatica	0.994	0.006	0.000
K50-K52 Noninfective enteritis and colitis	0.000	0.007	0.993
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.992	0.008	0.000
M35 Other systemic involvement of connective tissue	0.989	0.011	0.000
M20-M25 Other joint disorders	0.988	0.012	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.013	0.987
K51.9 Ulcerative colitis, unspecified	0.000	0.026	0.974
K50.9 Crohn's disease, unspecified	0.000	0.032	0.968
M86-M90 Other osteopathies	0.967	0.033	0.000
M45-M49 Spondylopathies	0.965	0.035	0.000
M45 Ankylosing spondylitis	0.960	0.040	0.000
M89 Other disorders of bone	0.955	0.045	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.048	0.952
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.952	0.048	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.948	0.052	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.947	0.053	0.000
M89.9 Disorder of bone, unspecified	0.938	0.062	0.000
M65-M68 Disorders of synovium and tendon	0.924	0.076	0.000
M06.3 Rheumatoid nodule	0.922	0.078	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.078	0.922
K51.4 Pseudopolyposis of colon	0.000	0.079	0.921
K90 Intestinal malabsorption	0.000	0.090	0.910
K50.0 Crohn's disease of small intestine	0.000	0.101	0.899
M89.94 Disorder of bone, unspecified (Hand)	0.888	0.112	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.887	0.113	0.000
M34 Systemic sclerosis	0.872	0.128	0.000
M65 Synovitis and tenosynovitis	0.871	0.129	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.871	0.129	0.000
K52 Other non-infective gastro-enteritis and colitis	0.000	0.134	0.866
K51.5 Mucosal proctocolitis	0.000	0.136	0.864
M60-M63 Disorders of muscles	0.850	0.150	0.000
M30 Polyarteritis nodosa and related conditions	0.850	0.150	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.849	0.151	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.160	0.840
M24 Other specific joint derangements	0.839	0.161	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.834	0.166	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.831	0.169	0.000
K90-K93 Other diseases of the digestive system	0.000	0.172	0.828
M89.0 Algoneurodystrophy	0.828	0.172	0.000
M06.34 Rheumatoid nodule (Hand)	0.817	0.183	0.000
M35.1 Other overlap syndromes	0.815	0.185	0.000
K51.8 Other ulcerative colitis	0.000	0.186	0.814
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.814	0.186	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.813	0.187	0.000
K50.8 Other Crohn's disease	0.000	0.189	0.811
M89.96 Disorder of bone, unspecified (Lower leg)	0.805	0.195	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.801	0.199	0.000
Chapter XI Diseases of the digestive system	0.000	0.203	0.797
M66 Spontaneous rupture of synovium and tendon	0.784	0.216	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.777	0.223	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.777	0.223	0.000
M34.9 Systemic sclerosis, unspecified	0.772	0.228	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.771	0.229	0.000
M24.5 Contracture of joint	0.770	0.230	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.231	0.769
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.767	0.233	0.000
M65.8 Other synovitis and tenosynovitis	0.750	0.250	0.000
M35.8 Other specified systemic involvement of connective tissue	0.750	0.250	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.749	0.251	0.000
M49 Spondylopathies in diseases classified elsewhere	0.747	0.252	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.744	0.256	0.000
M12 Other specific arthropathies	0.742	0.257	0.000
M62 Other disorders of muscle	0.737	0.263	0.000
M24.0 Loose body in joint	0.725	0.275	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.723	0.277	0.000
M24.54 Contracture of joint (Hand)	0.721	0.279	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.280	0.719
M30.0 Polyarteritis nodosa	0.718	0.282	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M05.8 Other seropositive rheumatoid arthritis	0.716	0.284	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.716	0.284	0.000
M05.2 Rheumatoid vasculitis	0.716	0.284	0.000
M05.1 Rheumatoid lung disease	0.716	0.284	0.000
M05.0 Felty's syndrome	0.716	0.284	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.716	0.284	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.716	0.284	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.716	0.284	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.716	0.284	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.716	0.284	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.716	0.284	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.286	0.714
K70-K77 Diseases of liver	0.000	0.291	0.709
M35.9 Systemic involvement of connective tissue, unspecified	0.709	0.291	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.709	0.291	0.000
M35.5 Multifocal fibrosclerosis	0.709	0.291	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.709	0.291	0.000
M35.2 Behcet's disease	0.709	0.291	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.708	0.292	0.000
M22 Disorders of patella	0.704	0.296	0.000
M46 Other inflammatory spondylopathies	0.700	0.300	0.000
J33.9 Nasal polyp, unspecified	0.699	0.301	0.000
M89.3 Hypertrophy of bone	0.696	0.304	0.000
J33.0 Polyp of nasal cavity	0.695	0.305	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.693	0.307	0.000
J33 Nasal polyp	0.693	0.307	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.688	0.311	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.688	0.311	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.688	0.311	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.688	0.311	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.688	0.311	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.688	0.311	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.688	0.311	0.000
M34.1 CR(E)ST syndrome	0.688	0.312	0.000
M89.6 Osteopathy after poliomyelitis	0.685	0.315	0.000
M89.2 Other disorders of bone development and growth	0.685	0.315	0.000
M89.1 Epiphyseal arrest	0.685	0.315	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.681	0.319	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.681	0.319	0.000
M14 Arthropathies in other diseases classified elsewhere	0.681	0.319	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.680	0.319	0.000
M00-M03 Infectious arthropathies	0.678	0.322	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.324	0.676
M89.99 Disorder of bone, unspecified (Site unspecified)	0.673	0.327	0.000
M89.98 Disorder of bone, unspecified (Other)	0.673	0.327	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.673	0.327	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.673	0.327	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.673	0.327	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.672	0.328	0.000
M88 Paget's disease of bone [osteitis deformans]	0.671	0.329	0.000
M32 Systemic lupus erythematosus	0.671	0.329	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.669	0.331	0.000
M86 Osteomyelitis	0.669	0.331	0.000
K70 Alcoholic liver disease	0.000	0.333	0.667
M89.03 Algoneurodystrophy (Forearm)	0.667	0.333	0.000
M33 Dermatopolymyositis	0.666	0.333	0.000
M10 Gout	0.665	0.335	0.000
M66.2 Spontaneous rupture of extensor tendons	0.663	0.337	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.662	0.338	0.000
M90 Osteopathies in diseases classified elsewhere	0.661	0.339	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.661	0.339	0.000
M06.38 Rheumatoid nodule (Other)	0.661	0.339	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.661	0.339	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.661	0.339	0.000
M06.33 Rheumatoid nodule (Forearm)	0.661	0.339	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.661	0.339	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.661	0.339	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.659	0.341	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.343	0.657
M89.5 Osteolysis	0.654	0.346	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.347	0.652
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.347	0.652
K90.1 Tropical sprue	0.000	0.347	0.652
M62.8 Other specified disorders of muscle	0.646	0.354	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.643	0.357	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.642	0.358	0.000
M24.1 Other articular cartilage disorders	0.642	0.358	0.000
M87 Osteonecrosis	0.640	0.360	0.000
K50.1 Crohn's disease of large intestine	0.000	0.363	0.637
M24.02 Loose body in joint (Upper arm)	0.635	0.365	0.000
M60 Myositis	0.635	0.365	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.631	0.369	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.631	0.369	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.629	0.371	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.625	0.374	0.000
M34.0 Progressive systemic sclerosis	0.625	0.374	0.000
M65.2 Calcific tendinitis	0.625	0.375	0.000
M65.0 Abscess of tendon sheath	0.625	0.375	0.000
K52.3 Indeterminate colitis	0.000	0.376	0.624
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.623	0.377	0.000
M31 Other necrotising vasculopathies	0.621	0.379	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.379	0.621
M24.7 Protrusio acetabuli	0.619	0.381	0.000
M65.1 Other infective (teno)synovitis	0.618	0.381	0.000
M06.4 Inflammatory polyarthropathy	0.618	0.382	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.616	0.383	0.000
K65-K67 Diseases of peritoneum	0.000	0.388	0.612
M24.16 Other articular cartilage disorders (Lower leg)	0.611	0.389	0.000
M89.04 Algoneurodystrophy (Hand)	0.611	0.389	0.000
M89.8 Other specified disorders of bone	0.611	0.389	0.000
M21 Other acquired deformities of limbs	0.611	0.389	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.610	0.390	0.000
M61 Calcification and ossification of muscle	0.610	0.390	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.610	0.390	0.000
K90.8 Other intestinal malabsorption	0.000	0.390	0.609
M30.8 Other conditions related to polyarteritis nodosa	0.609	0.391	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.609	0.391	0.000
M30.2 Juvenile polyarteritis	0.609	0.391	0.000
M11 Other crystal arthropathies	0.602	0.398	0.000
M66.4 Spontaneous rupture of other tendons	0.602	0.398	0.000
M24.9 Joint derangement, unspecified	0.602	0.398	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.602	0.398	0.000
M34.8 Other forms of systemic sclerosis	0.601	0.399	0.000
K75 Other inflammatory liver diseases	0.000	0.399	0.601
M89.06 Algoneurodystrophy (Lower leg)	0.601	0.399	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.400	0.600
K70.9 Alcoholic liver disease, unspecified	0.000	0.401	0.599
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.596	0.404	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.596	0.404	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.406	0.594
M89.09 Algoneurodystrophy (Site unspecified)	0.593	0.406	0.000
M89.08 Algoneurodystrophy (Other)	0.593	0.406	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.593	0.406	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.593	0.406	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.593	0.406	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.593	0.406	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.593	0.407	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.592	0.408	0.000
K35-K38 Diseases of appendix	0.000	0.409	0.591
M65.83 Other synovitis and tenosynovitis (Forearm)	0.582	0.418	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.580	0.420	0.000
M24.6 Ankylosis of joint	0.577	0.423	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.576	0.424	0.000
M24.07 Loose body in joint (Ankle and foot)	0.574	0.426	0.000
M66.3 Spontaneous rupture of flexor tendons	0.569	0.431	0.000
M22.2 Patellofemoral disorders	0.568	0.432	0.000
K73 Chronic hepatitis, not elsewhere classified	0.000	0.434	0.566
M62.88 Other specified disorders of muscle (Other)	0.564	0.436	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.562	0.438	0.000
M66.1 Rupture of synovium	0.562	0.438	0.000
M46.2 Osteomyelitis of vertebra	0.558	0.442	0.000
J33.8 Other polyp of sinus	0.558	0.442	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.447	0.553
M66.0 Rupture of popliteal cyst	0.552	0.448	0.000
M24.59 Contracture of joint (Site unspecified)	0.552	0.448	0.000
M24.58 Contracture of joint (Other)	0.552	0.448	0.000
M24.57 Contracture of joint (Ankle and foot)	0.552	0.448	0.000
M24.56 Contracture of joint (Lower leg)	0.552	0.448	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.552	0.448	0.000
M24.53 Contracture of joint (Forearm)	0.552	0.448	0.000
M24.52 Contracture of joint (Upper arm)	0.552	0.448	0.000
M24.51 Contracture of joint (Shoulder region)	0.552	0.448	0.000
M24.50 Contracture of joint (Multiple sites)	0.552	0.448	0.000
M12.2 Villonodular synovitis (pigmented)	0.552	0.448	0.000
M62.6 Muscle strain	0.551	0.449	0.000
M46.4 Discitis, unspecified	0.546	0.454	0.000
M12.3 Palindromic rheumatism	0.539	0.461	0.000
K37 Unspecified appendicitis	0.000	0.461	0.539
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.538	0.462	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.538	0.462	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.538	0.462	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.538	0.462	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.538	0.462	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.538	0.462	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.536	0.464	0.000
M49.4 Neuropathic spondylopathy	0.536	0.464	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.536	0.464	0.000
M49.2 Enterobacterial spondylitis	0.536	0.464	0.000
M49.1 Brucella spondylitis	0.536	0.464	0.000
M49.0 Tuberculosis of spine	0.536	0.464	0.000
K70.4 Alcoholic hepatic failure	0.000	0.465	0.535
K74 Fibrosis and cirrhosis of liver	0.000	0.465	0.535
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.534	0.466	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.534	0.466	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.534	0.466	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.534	0.466	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.534	0.466	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.534	0.466	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.534	0.466	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.534	0.466	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.534	0.466	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.534	0.466	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.533	0.467	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.532	0.467	0.000
M12.5 Traumatic arthropathy	0.532	0.467	0.000
M12.4 Intermittent hydrarthrosis	0.532	0.467	0.000
M12.1 Kaschin-Beck disease	0.532	0.467	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.532	0.467	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.470	0.530
M62.9 Disorder of muscle, unspecified	0.529	0.471	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.529	0.471	0.000
M62.4 Contracture of muscle	0.529	0.471	0.000
M62.3 Immobility syndrome (paraplegic)	0.529	0.471	0.000
M62.2 Ischaemic infarction of muscle	0.529	0.471	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.529	0.471	0.000
M62.0 Diastasis of muscle	0.529	0.471	0.000
M22.0 Recurrent dislocation of patella	0.522	0.478	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.522	0.478	0.000
M24.09 Loose body in joint (Site unspecified)	0.520	0.480	0.000
M24.08 Loose body in joint (Other)	0.520	0.480	0.000
M24.06 Loose body in joint-Lower leg	0.520	0.480	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.520	0.480	0.000
M24.04 Loose body in joint (Hand)	0.520	0.480	0.000
M24.03 Loose body in joint (Forearm)	0.520	0.480	0.000
M24.00 Loose body in joint (Multiple sites)	0.520	0.480	0.000
M07 Psoriatic and enteropathic arthropathies	0.517	0.482	0.001
M62.89 Other specified disorders of muscle (Site unspecified)	0.515	0.485	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.515	0.485	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.514	0.486	0.000
M06.18 Adult-onset Still's disease (Other)	0.514	0.486	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.514	0.486	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.514	0.486	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.514	0.486	0.000
M06.14 Adult-onset Still's disease (Hand)	0.514	0.486	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.514	0.486	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.514	0.486	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.514	0.486	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.514	0.486	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.514	0.486	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.514	0.486	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.514	0.486	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.514	0.486	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.514	0.486	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.514	0.486	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.514	0.486	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.514	0.486	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.514	0.486	0.000
M08.9 Juvenile arthritis, unspecified	0.514	0.486	0.000
M08.8 Other juvenile arthritis	0.514	0.486	0.000
M08.4 Pauciarticular juvenile arthritis	0.514	0.486	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.514	0.486	0.000
M08.2 Juvenile arthritis with systemic onset	0.514	0.486	0.000
M08.1 Juvenile ankylosing spondylitis	0.514	0.486	0.000
M08.0 Juvenile rheumatoid arthritis	0.514	0.486	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.514	0.486	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.514	0.486	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.514	0.486	0.000
M09.0 Juvenile arthritis in psoriasis	0.514	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.513	0.486	0.000
M05.08 Felty's syndrome (Other)	0.513	0.486	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.513	0.486	0.000
M05.06 Felty's syndrome (Lower leg)	0.513	0.486	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.513	0.486	0.000
M05.04 Felty's syndrome (Hand)	0.513	0.486	0.000
M05.03 Felty's syndrome (Forearm)	0.513	0.486	0.000
M05.02 Felty's syndrome (Upper arm)	0.513	0.486	0.000
M05.01 Felty's syndrome (Shoulder region)	0.513	0.486	0.000
M05.00 Felty's syndrome (Multiple sites)	0.513	0.486	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.513	0.486	0.000
M05.18 Rheumatoid lung disease (Other)	0.513	0.486	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.513	0.486	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.513	0.486	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.513	0.486	0.000
M05.14 Rheumatoid lung disease (Hand)	0.513	0.486	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.513	0.486	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.513	0.486	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.513	0.486	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.513	0.486	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.513	0.486	0.000
M05.28 Rheumatoid vasculitis (Other)	0.513	0.486	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.513	0.486	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.513	0.486	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.513	0.486	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.513	0.486	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.513	0.486	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.513	0.486	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.513	0.486	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.513	0.486	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.513	0.486	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.513	0.486	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.513	0.486	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.513	0.486	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.513	0.486	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.513	0.486	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.513	0.486	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.513	0.486	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.513	0.486	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.513	0.486	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.513	0.486	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.513	0.486	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.513	0.486	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.513	0.486	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.513	0.486	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.513	0.486	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.513	0.486	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.513	0.486	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.513	0.486	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.513	0.486	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.511	0.489	0.000
M13 Other arthritis	0.510	0.490	0.000
K77 Liver disorders in diseases classified elsewhere	0.000	0.491	0.509
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.508	0.491	0.000
M91-M94 Chondropathies	0.508	0.492	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.508	0.492	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.508	0.492	0.000
M36.3 Arthropathy in other blood disorders	0.508	0.492	0.000
M36.2 Haemophilic arthropathy	0.508	0.492	0.000
M36.1 Arthropathy in neoplastic disease	0.508	0.492	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.508	0.492	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.507	0.493	0.000
M22.1 Recurrent subluxation of patella	0.505	0.495	0.000
M22.9 Disorder of patella, unspecified	0.505	0.495	0.000
M46.8 Other specified inflammatory spondylopathies	0.502	0.498	0.000
M46.5 Other infective spondylopathies	0.502	0.498	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.502	0.498	0.000
M46.0 Spinal enthesopathy	0.502	0.498	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.501	0.499	0.000
M80-M85 Disorders of bone density and structure	0.501	0.499	0.000
K70.1 Alcoholic hepatitis	0.000	0.500	0.499
M89.39 Hypertrophy of bone (Site unspecified)	0.499	0.501	0.000
M89.38 Hypertrophy of bone (Other)	0.499	0.501	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.499	0.501	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.499	0.501	0.000
M89.34 Hypertrophy of bone (Hand)	0.499	0.501	0.000
M89.33 Hypertrophy of bone (Forearm)	0.499	0.501	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.499	0.501	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.499	0.501	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.499	0.501	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.498	0.502	0.000
J33.1 Polypoid sinus degeneration	0.497	0.503	0.000
M60.0 Infective myositis	0.496	0.503	0.000
M21.0 Valgus deformity, not elsewhere classified	0.496	0.503	0.000
K65 Peritonitis	0.000	0.504	0.496
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.495	0.504	0.000
M22.3 Other derangements of patella	0.493	0.507	0.000
M48 Other spondylopathies	0.491	0.508	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.491	0.509	0.000
M89.18 Epiphyseal arrest (Other)	0.491	0.509	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.491	0.509	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.491	0.509	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.491	0.509	0.000
M89.14 Epiphyseal arrest (Hand)	0.491	0.509	0.000
M89.13 Epiphyseal arrest (Forearm)	0.491	0.509	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.491	0.509	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.491	0.509	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.491	0.509	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.491	0.509	0.000
M89.28 Other disorders of bone development and growth (Other)	0.491	0.509	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.491	0.509	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.491	0.509	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.491	0.509	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.491	0.509	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.491	0.509	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.491	0.509	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.491	0.509	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.491	0.509	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.491	0.509	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.491	0.509	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.491	0.509	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.491	0.509	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.491	0.509	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.491	0.509	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.491	0.509	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.491	0.509	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.491	0.509	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.491	0.509	0.000
M86.6 Other chronic osteomyelitis	0.490	0.510	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.488	0.512	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.488	0.512	0.000
M14.4 Arthropathy in amyloidosis	0.488	0.512	0.000
M14.3 Lipoid dermatoarthritis	0.488	0.512	0.000
M14.2 Diabetic arthropathy	0.488	0.512	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.488	0.512	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.488	0.512	0.000
K74.0 Hepatic fibrosis	0.000	0.513	0.487
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.486	0.514	0.000
M02 Reactive arthropathies	0.486	0.514	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.486	0.514	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.516	0.484
M06.0 Seronegative rheumatoid arthritis	0.483	0.517	0.000
M22.4 Chondromalacia patellae	0.483	0.517	0.000
K92 Other diseases of digestive system	0.000	0.518	0.482
M88.8 Paget's disease of other bones	0.481	0.519	0.000
M88.0 Paget's disease of skull	0.481	0.519	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.481	0.519	0.000
M32.8 Other forms of systemic lupus erythematosus	0.481	0.519	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.481	0.519	0.000
K52.1 Toxic gastro-enteritis and colitis	0.000	0.519	0.481
M86.8 Other osteomyelitis	0.480	0.520	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.480	0.520	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.480	0.520	0.000
M86.3 Chronic multifocal osteomyelitis	0.480	0.520	0.000
M86.2 Subacute osteomyelitis	0.480	0.520	0.000
M86.1 Other acute osteomyelitis	0.480	0.520	0.000
M86.0 Acute haematogenous osteomyelitis	0.480	0.520	0.000
M33.9 Dermatopolymyositis, unspecified	0.478	0.522	0.000
M33.1 Other dermatomyositis	0.478	0.522	0.000
M33.0 Juvenile dermatomyositis	0.478	0.522	0.000
M10.4 Other secondary gout	0.477	0.523	0.000
M10.3 Gout due to impairment of renal function	0.477	0.523	0.000
M10.2 Drug-induced gout	0.477	0.523	0.000
M10.1 Lead-induced gout	0.477	0.523	0.000
M10.0 Idiopathic gout	0.477	0.523	0.000
M87.2 Osteonecrosis due to previous trauma	0.476	0.523	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.475	0.525	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.475	0.525	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.475	0.525	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.475	0.525	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.475	0.525	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.475	0.525	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.475	0.525	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.475	0.525	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.475	0.525	0.000
M24.01 Loose body in joint (Shoulder region)	0.475	0.525	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.475	0.525	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.475	0.525	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations