TreeWAS – Variant ID: rs12705959

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M25.5 Pain in joint	0.000	0.357	0.643
M25 Other joint disorders, not elsewhere classified	0.000	0.357	0.643
M20.4 Other hammer toe(s) (acquired)	0.000	0.365	0.635
M25.57 Pain in joint (Ankle and foot)	0.000	0.369	0.631
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.372	0.628
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.373	0.627
M25.51 Pain in joint (Shoulder region)	0.000	0.388	0.612
M20 Acquired deformities of fingers and toes	0.000	0.390	0.610
M20-M25 Other joint disorders	0.000	0.400	0.600
M31 Other necrotising vasculopathies	0.000	0.430	0.570
M25.4 Effusion of joint	0.000	0.440	0.560
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.448	0.552
M31.3 Wegener's granulomatosis	0.000	0.458	0.542
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.463	0.537
M22 Disorders of patella	0.000	0.470	0.530
M25.3 Other instability of joint	0.000	0.475	0.525
M22.4 Chondromalacia patellae	0.000	0.478	0.522
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.482	0.518
M20.5 Other deformities of toe(s) (acquired)	0.000	0.490	0.510
M30 Polyarteritis nodosa and related conditions	0.000	0.499	0.501
M20.0 Deformity of finger(s)	0.000	0.501	0.499
M25.47 Effusion of joint (Ankle and foot)	0.000	0.505	0.495
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.508	0.492
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.508	0.492
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.511	0.489
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.513	0.487
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.537	0.463
M25.40 Effusion of joint (Multiple sites)	0.000	0.538	0.462
M33 Dermatopolymyositis	0.000	0.538	0.462
M25.2 Flail joint	0.000	0.539	0.461
M25.1 Fistula of joint	0.000	0.539	0.461
M25.56 Pain in joint (Lower leg)	0.000	0.540	0.460
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.541	0.459
M25.41 Effusion of joint (Shoulder region)	0.000	0.541	0.459
M25.8 Other specified joint disorders	0.000	0.543	0.457
M25.9 Joint disorder, unspecified	0.000	0.550	0.450
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.550	0.450
M31.6 Other giant cell arteritis	0.000	0.554	0.446
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.560	0.440
M31.9 Necrotising vasculopathy, unspecified	0.000	0.565	0.435
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.565	0.435
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.565	0.434
M20.1 Hallux valgus (acquired)	0.000	0.571	0.429
M25.37 Other instability of joint (Ankle and foot)	0.000	0.573	0.427
M30.0 Polyarteritis nodosa	0.000	0.575	0.425
M31.8 Other specified necrotising vasculopathies	0.000	0.580	0.420
M22.0 Recurrent dislocation of patella	0.000	0.581	0.419
M25.50 Pain in joint (Multiple sites)	0.000	0.586	0.414
M25.59 Pain in joint (Site unspecified)	0.000	0.587	0.413
M25.0 Haemarthrosis	0.000	0.589	0.411
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.591	0.409
M31.2 Lethal midline granuloma	0.000	0.591	0.409
M31.1 Thrombotic microangiopathy	0.000	0.591	0.409
M31.0 Hypersensitivity angiitis	0.000	0.593	0.407
M25.52 Pain in joint (Upper arm)	0.000	0.595	0.405
M25.34 Other instability of joint (Hand)	0.000	0.596	0.404
M31.7 Microscopic polyangiitis	0.000	0.597	0.403
M25.49 Effusion of joint (Site unspecified)	0.000	0.599	0.401
M25.48 Effusion of joint (Other)	0.000	0.599	0.401
M25.44 Effusion of joint (Hand)	0.000	0.600	0.399
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.600	0.400
M25.31 Other instability of joint (Shoulder region)	0.000	0.609	0.391
M22.9 Disorder of patella, unspecified	0.000	0.612	0.388
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.618	0.381
M22.1 Recurrent subluxation of patella	0.000	0.620	0.380
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.620	0.380
M32 Systemic lupus erythematosus	0.000	0.621	0.379
M25.88 Other specified joint disorders (Other)	0.000	0.622	0.378
M25.39 Other instability of joint (Site unspecified)	0.000	0.624	0.376
M25.38 Other instability of joint (Other)	0.000	0.624	0.376
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.624	0.376
M25.32 Other instability of joint (Upper arm)	0.000	0.624	0.376
M25.30 Other instability of joint (Multiple sites)	0.000	0.624	0.376
M25.36 Other instability of joint (Lower leg)	0.000	0.627	0.373
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.633	0.367
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.641	0.359
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.641	0.359
M30.2 Juvenile polyarteritis	0.000	0.641	0.359
M25.46 Effusion of joint (Lower leg)	0.000	0.648	0.352
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.649	0.351
M25.33 Other instability of joint (Forearm)	0.000	0.649	0.351
M33.1 Other dermatomyositis	0.000	0.650	0.350
M33.2 Polymyositis	0.000	0.654	0.346
M25.58 Pain in joint (Other)	0.000	0.655	0.345
M25.7 Osteophyte	0.000	0.656	0.344
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.661	0.339
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.665	0.335
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.668	0.331
M33.9 Dermatopolymyositis, unspecified	0.000	0.669	0.331
M33.0 Juvenile dermatomyositis	0.000	0.669	0.331
M25.19 Fistula of joint (Site unspecified)	0.000	0.669	0.330
M25.18 Fistula of joint (Other)	0.000	0.669	0.330
M25.17 Fistula of joint (Ankle and foot)	0.000	0.669	0.330
M25.16 Fistula of joint (Lower leg)	0.000	0.669	0.330
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.669	0.330
M25.14 Fistula of joint (Hand)	0.000	0.669	0.330
M25.13 Fistula of joint (Forearm)	0.000	0.669	0.330
M25.12 Fistula of joint (Upper arm)	0.000	0.669	0.330
M25.11 Fistula of joint (Shoulder region)	0.000	0.669	0.330
M25.10 Fistula of joint (Multiple sites)	0.000	0.669	0.330
M25.29 Flail joint (Site unspecified)	0.000	0.669	0.330
M25.28 Flail joint (Other)	0.000	0.669	0.330
M25.27 Flail joint (Ankle and foot)	0.000	0.669	0.330
M25.26 Flail joint (Lower leg)	0.000	0.669	0.330
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.669	0.330
M25.24 Flail joint (Hand)	0.000	0.669	0.330
M25.23 Flail joint (Forearm)	0.000	0.669	0.330
M25.22 Flail joint (Upper arm)	0.000	0.669	0.330
M25.21 Flail joint (Shoulder region)	0.000	0.669	0.330
M25.20 Flail joint (Multiple sites)	0.000	0.669	0.330
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.672	0.328
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.672	0.328
M25.82 Other specified joint disorders (Upper arm)	0.000	0.672	0.328
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.672	0.328
M25.98 Joint disorder, unspecified (Other)	0.000	0.677	0.323
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.677	0.323
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.677	0.323
M25.53 Pain in joint (Forearm)	0.000	0.680	0.319
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.684	0.316
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.687	0.313
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.688	0.312
M36.3 Arthropathy in other blood disorders	0.000	0.688	0.312
M36.2 Haemophilic arthropathy	0.000	0.688	0.312
M36.1 Arthropathy in neoplastic disease	0.000	0.688	0.312
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.688	0.312
M22.8 Other disorders of patella	0.000	0.689	0.311
M25.42 Effusion of joint (Upper arm)	0.000	0.692	0.308
M25.09 Haemarthrosis (Site unspecified)	0.000	0.705	0.295
M25.08 Haemarthrosis (Other)	0.000	0.705	0.295
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.705	0.295
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.705	0.295
M25.04 Haemarthrosis (Hand)	0.000	0.705	0.295
M25.03 Haemarthrosis (Forearm)	0.000	0.705	0.295
M25.02 Haemarthrosis (Upper arm)	0.000	0.705	0.295
M25.01 Haemarthrosis (Shoulder region)	0.000	0.705	0.295
M25.00 Haemarthrosis (Multiple sites)	0.000	0.705	0.295
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.706	0.294
M25.78 Osteophyte (Other)	0.000	0.712	0.288
M25.54 Pain in joint (Hand)	0.000	0.720	0.280
M25.94 Joint disorder, unspecified (Hand)	0.000	0.723	0.277
M25.43 Effusion of joint (Forearm)	0.000	0.727	0.273
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.727	0.273
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.728	0.271
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.728	0.271
M32.8 Other forms of systemic lupus erythematosus	0.000	0.733	0.267
M25.77 Osteophyte (Ankle and foot)	0.000	0.743	0.257
M25.79 Osteophyte (Site unspecified)	0.000	0.744	0.255
M25.70 Osteophyte (Multiple sites)	0.000	0.753	0.247
M25.84 Other specified joint disorders (Hand)	0.000	0.754	0.246
M25.06 Haemarthrosis (Lower leg)	0.000	0.755	0.245
M22.3 Other derangements of patella	0.000	0.755	0.245
M25.72 Osteophyte (Upper arm)	0.000	0.760	0.240
M25.74 Osteophyte (Hand)	0.000	0.764	0.236
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.774	0.226
M25.73 Osteophyte (Forearm)	0.000	0.774	0.226
M34 Systemic sclerosis	0.000	0.775	0.225
M25.76 Osteophyte (Lower leg)	0.000	0.779	0.221
M20.3 Other deformity of hallux (acquired)	0.000	0.782	0.218
M25.83 Other specified joint disorders (Forearm)	0.001	0.800	0.200
M35 Other systemic involvement of connective tissue	0.000	0.802	0.198
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.000	0.805	0.195
M25.71 Osteophyte (Shoulder region)	0.000	0.806	0.194
M25.86 Other specified joint disorders (Lower leg)	0.000	0.807	0.193
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.818	0.182
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.838	0.161
M35.7 Hypermobility syndrome	0.000	0.839	0.161
M34.8 Other forms of systemic sclerosis	0.000	0.845	0.155
M35.2 Behcet's disease	0.000	0.853	0.147
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.858	0.142
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.858	0.142
M35.5 Multifocal fibrosclerosis	0.000	0.858	0.142
M34.0 Progressive systemic sclerosis	0.000	0.860	0.140
M35.8 Other specified systemic involvement of connective tissue	0.000	0.867	0.133
M20.2 Hallux rigidus	0.000	0.870	0.130
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.874	0.126
M22.2 Patellofemoral disorders	0.001	0.880	0.120
M34.9 Systemic sclerosis, unspecified	0.000	0.882	0.117
M34.1 CR(E)ST syndrome	0.000	0.883	0.117
M35.0 Sicca syndrome [Sjogren]	0.000	0.889	0.111
M24 Other specific joint derangements	0.000	0.896	0.104
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.898	0.102
M35.1 Other overlap syndromes	0.000	0.904	0.096
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.912	0.088
M35.3 Polymyalgia rheumatica	0.000	0.912	0.088
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.915	0.085
M21 Other acquired deformities of limbs	0.000	0.920	0.080
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.925	0.075
M24.9 Joint derangement, unspecified	0.000	0.925	0.075
M24.7 Protrusio acetabuli	0.000	0.928	0.072
M24.0 Loose body in joint	0.000	0.928	0.072
M24.6 Ankylosis of joint	0.000	0.931	0.069
M21.6 Other acquired deformities of ankle and foot	0.000	0.932	0.067
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.936	0.064
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.936	0.064
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.936	0.064
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.936	0.064
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.936	0.064
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.936	0.064
M19.99 Arthrosis, unspecified (Site unspecified)	0.000	0.937	0.063
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.939	0.061
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.940	0.060
M21.9 Acquired deformity of limb, unspecified	0.000	0.940	0.060
M21.2 Flexion deformity	0.000	0.941	0.059
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.941	0.059
M24.04 Loose body in joint (Hand)	0.000	0.944	0.056
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.000	0.944	0.056
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.000	0.946	0.054
M24.07 Loose body in joint (Ankle and foot)	0.000	0.946	0.054
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.000	0.946	0.054
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.000	0.946	0.054
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.000	0.946	0.054
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.946	0.054
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.000	0.946	0.054
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.000	0.946	0.054
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.000	0.946	0.054
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.000	0.946	0.054
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.000	0.946	0.054
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.946	0.054
M24.98 Joint derangement, unspecified (Other)	0.000	0.946	0.054
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.946	0.054
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.946	0.054
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.946	0.054
M24.94 Joint derangement, unspecified (Hand)	0.000	0.946	0.054
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.946	0.054
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.946	0.054
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.946	0.054
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.946	0.054
M24.06 Loose body in joint-Lower leg	0.000	0.947	0.053
M21.8 Other specified acquired deformities of limbs	0.000	0.948	0.051
M24.79 Protrusio acetabuli-Site unspec	0.000	0.948	0.052
M24.78 Protrusio acetabuli-Other	0.000	0.948	0.052
M24.77 Protrusio acetabuli-Ankle/foot	0.000	0.948	0.052
M24.76 Protrusio acetabuli-Lower leg	0.000	0.948	0.052
M24.74 Protrusio acetabuli-Hand	0.000	0.948	0.052
M24.73 Protrusio acetabuli-Forearm	0.000	0.948	0.052
M24.72 Protrusio acetabuli-Upper arm	0.000	0.948	0.052
M24.71 Protrusio acetabuli-Shldr region	0.000	0.948	0.052
M24.70 Protrusio acetabuli-Mult sites	0.000	0.948	0.052
M21.26 Flexion deformity (Lower leg)	0.000	0.948	0.052
M24.09 Loose body in joint (Site unspecified)	0.000	0.948	0.051
M24.08 Loose body in joint (Other)	0.000	0.948	0.051
M24.00 Loose body in joint (Multiple sites)	0.000	0.948	0.051
M24.64 Ankylosis of joint (Hand)	0.000	0.950	0.050
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.950	0.050
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.950	0.050
M24.66 Ankylosis of joint (Lower leg)	0.000	0.950	0.049
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.950	0.049
M24.68 Ankylosis of joint (Other)	0.000	0.950	0.049
M24.63 Ankylosis of joint (Forearm)	0.000	0.950	0.049
M24.62 Ankylosis of joint (Upper arm)	0.000	0.950	0.049
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.950	0.049
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.950	0.049
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.951	0.049
M24.75 Protrusio acetabuli-Pelvic/thigh	0.000	0.951	0.049
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.951	0.049
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.951	0.049
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.951	0.049
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.951	0.049
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.951	0.049
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.951	0.049
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.951	0.049
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.951	0.049
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.951	0.049
M24.02 Loose body in joint (Upper arm)	0.000	0.951	0.049
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.951	0.048
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.000	0.952	0.048
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.952	0.048
M24.2 Disorder of ligament	0.000	0.952	0.048
M24.01 Loose body in joint (Shoulder region)	0.000	0.952	0.047
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.953	0.047
M24.03 Loose body in joint (Forearm)	0.000	0.953	0.047
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.953	0.046
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.954	0.045
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.954	0.045
M21.4 Flat foot [pes planus] (acquired)	0.001	0.955	0.045
M21.0 Valgus deformity, not elsewhere classified	0.000	0.955	0.045
M21.24 Flexion deformity (Hand)	0.000	0.955	0.045
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.956	0.044
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.956	0.044
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.957	0.043
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.957	0.043
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.957	0.043
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.957	0.043
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.957	0.043
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.957	0.043
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.957	0.043
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.957	0.043
M21.29 Flexion deformity (Site unspecified)	0.000	0.957	0.042
M21.28 Flexion deformity (Other)	0.000	0.957	0.042
M21.22 Flexion deformity (Upper arm)	0.000	0.957	0.042
M21.21 Flexion deformity (Shoulder region)	0.000	0.957	0.042
M21.20 Flexion deformity (Multiple sites)	0.000	0.957	0.042
M24.5 Contracture of joint	0.000	0.959	0.041
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.959	0.041
M21.3 Wrist or foot drop (acquired)	0.000	0.960	0.040
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.960	0.039
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.961	0.039
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.961	0.039
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.000	0.961	0.039
M21.23 Flexion deformity (Forearm)	0.000	0.962	0.037
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.963	0.037
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.963	0.037
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.963	0.037
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.963	0.037
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.963	0.037
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.963	0.037
M24.26 Disorder of ligament (Lower leg)	0.000	0.963	0.037
M24.24 Disorder of ligament (Hand)	0.000	0.963	0.036
M21.7 Unequal limb length (acquired)	0.001	0.964	0.036
M21.27 Flexion deformity (Ankle and foot)	0.000	0.965	0.035
M24.29 Disorder of ligament (Site unspecified)	0.000	0.966	0.034
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.966	0.034
M24.22 Disorder of ligament (Upper arm)	0.000	0.966	0.034
M24.20 Disorder of ligament (Multiple sites)	0.000	0.966	0.034
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.966	0.034
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.967	0.033
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.967	0.032
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.967	0.032
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.967	0.032
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.967	0.032
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.967	0.032
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.967	0.032
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.967	0.032
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.967	0.032
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.001	0.967	0.032
M21.48 Flat foot [pes planus] (acquired)-Other	0.001	0.967	0.032
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.001	0.967	0.032
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.001	0.967	0.032
M21.44 Flat foot [pes planus] (acquired)-Hand	0.001	0.967	0.032
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.001	0.967	0.032
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.001	0.967	0.032
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.001	0.967	0.032
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.001	0.967	0.032
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.967	0.032
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.967	0.032
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.967	0.032
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.967	0.032
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.967	0.032
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.967	0.032
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.967	0.032
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.967	0.032
M21.83 Other specified acquired deformities of limbs (Forearm)	0.001	0.967	0.032
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.000	0.967	0.032
M24.21 Disorder of ligament (Shoulder region)	0.000	0.967	0.032
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.001	0.968	0.032
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.001	0.968	0.031
M21.1 Varus deformity, not elsewhere classified	0.001	0.969	0.031
M24.57 Contracture of joint (Ankle and foot)	0.000	0.970	0.030
M24.59 Contracture of joint (Site unspecified)	0.000	0.970	0.030
M24.58 Contracture of joint (Other)	0.000	0.970	0.030
M24.53 Contracture of joint (Forearm)	0.000	0.970	0.030
M24.50 Contracture of joint (Multiple sites)	0.000	0.970	0.030
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.000	0.971	0.029
M24.52 Contracture of joint (Upper arm)	0.000	0.971	0.029
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.971	0.029
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.971	0.029
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.971	0.029
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.971	0.029
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.971	0.029
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.971	0.029
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.971	0.029
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.971	0.029
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.971	0.029
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.971	0.028
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.972	0.028
M24.1 Other articular cartilage disorders	0.000	0.972	0.028
M24.28 Disorder of ligament (Other)	0.000	0.973	0.026
M21.79 Unequal limb length (acquired) (Site unspecified)	0.001	0.974	0.026
M21.78 Unequal limb length (acquired)-Other	0.001	0.974	0.026
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.001	0.974	0.026
M21.74 Unequal limb length (acquired) (Hand)	0.001	0.974	0.026
M21.72 Unequal limb length (acquired) (Upper arm)	0.001	0.974	0.026
M21.71 Unequal limb length (acquired)-Shldr region	0.001	0.974	0.026
M21.70 Unequal limb length (acquired) (Multiple sites)	0.001	0.974	0.026
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.000	0.975	0.025
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.001	0.975	0.024
M24.56 Contracture of joint (Lower leg)	0.000	0.975	0.024
M24.51 Contracture of joint (Shoulder region)	0.000	0.975	0.024
M24.23 Disorder of ligament (Forearm)	0.000	0.976	0.024
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.976	0.024
M65-M68 Disorders of synovium and tendon	0.000	0.976	0.024
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.001	0.977	0.023
M24.54 Contracture of joint (Hand)	0.000	0.977	0.022
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.001	0.977	0.022
M21.18 Varus deformity, not elsewhere classified (Other)	0.001	0.977	0.022
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.001	0.977	0.022
M21.14 Varus deformity, not elsewhere classified (Hand)	0.001	0.977	0.022
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.001	0.977	0.022
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.001	0.977	0.022
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.001	0.977	0.022
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.001	0.977	0.022
M86-M90 Other osteopathies	0.000	0.977	0.023
M65 Synovitis and tenosynovitis	0.000	0.978	0.022
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.978	0.022
M21.73 Unequal limb length (acquired) (Forearm)	0.001	0.978	0.021
M67 Other disorders of synovium and tendon	0.000	0.978	0.022
N39.4 Other specified urinary incontinence	0.000	0.979	0.021
M15-M19 Arthrosis	0.000	0.979	0.021
M89 Other disorders of bone	0.000	0.979	0.021
M19 Other arthrosis	0.000	0.979	0.021
M67.1 Other contracture of tendon (sheath)	0.000	0.979	0.021
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.001	0.980	0.020
M19.9 Arthrosis, unspecified	0.000	0.980	0.020
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.980	0.020
M24.18 Other articular cartilage disorders (Other)	0.000	0.980	0.020
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.980	0.020
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.980	0.020
M65.3 Trigger finger	0.000	0.980	0.020
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.980	0.019
M24.14 Other articular cartilage disorders (Hand)	0.000	0.981	0.019
M65.8 Other synovitis and tenosynovitis	0.000	0.981	0.019
M89.0 Algoneurodystrophy	0.000	0.981	0.019
M00-M03 Infectious arthropathies	0.000	0.981	0.019
M18 Arthrosis of first carpometacarpal joint	0.000	0.981	0.019
M15 Polyarthrosis	0.000	0.981	0.019
M45-M49 Spondylopathies	0.000	0.981	0.019
M89.9 Disorder of bone, unspecified	0.000	0.981	0.018
M65.34 Trigger finger-Hand	0.000	0.982	0.018
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.982	0.018
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.982	0.018
M21.76 Unequal limb length (acquired) (Lower leg)	0.001	0.982	0.017
M67.0 Short Achilles tendon (acquired)	0.000	0.982	0.018
M86 Osteomyelitis	0.000	0.982	0.018
M89.8 Other specified disorders of bone	0.000	0.983	0.017
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.001	0.983	0.017
M47 Spondylosis	0.000	0.983	0.017
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.983	0.017
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.000	0.983	0.017
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.983	0.017
H61.0 Perichondritis of external ear	0.000	0.983	0.017
M19.0 Primary arthrosis of other joints	0.000	0.983	0.017
M89.04 Algoneurodystrophy (Hand)	0.000	0.983	0.017
M15.8 Other polyarthrosis	0.000	0.983	0.017
M91-M94 Chondropathies	0.000	0.983	0.017
M65.4 Radial styloid tenosynovitis [de Quervain]	0.000	0.983	0.017
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.983	0.017
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.983	0.017
M47.9 Spondylosis, unspecified	0.000	0.983	0.017
M19.2 Other secondary arthrosis	0.000	0.983	0.017
M65.2 Calcific tendinitis	0.000	0.983	0.016
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.983	0.017
M46 Other inflammatory spondylopathies	0.000	0.984	0.016
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.984	0.016
Y83.6 Removal of other organ (partial) (total)	0.016	0.984	0.000
M65.0 Abscess of tendon sheath	0.000	0.984	0.016
N39.3 Stress incontinence	0.000	0.984	0.016
M90 Osteopathies in diseases classified elsewhere	0.000	0.984	0.016
M65.83 Other synovitis and tenosynovitis (Forearm)	0.000	0.984	0.016
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.000	0.984	0.016
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.984	0.016
M67.9 Disorder of synovium and tendon, unspecified	0.000	0.984	0.016
M67.3 Transient synovitis	0.000	0.984	0.016
M89.07 Algoneurodystrophy (Ankle and foot)	0.000	0.984	0.016
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.984	0.016
M88 Paget's disease of bone [osteitis deformans]	0.000	0.984	0.015
M02 Reactive arthropathies	0.000	0.984	0.015
M89.6 Osteopathy after poliomyelitis	0.000	0.985	0.015
M89.2 Other disorders of bone development and growth	0.000	0.985	0.015
M89.1 Epiphyseal arrest	0.000	0.985	0.015
M15.3 Secondary multiple arthrosis	0.000	0.985	0.015
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.985	0.015
M89.88 Other specified disorders of bone (Other)	0.000	0.985	0.015
M89.06 Algoneurodystrophy (Lower leg)	0.000	0.985	0.015
M67.4 Ganglion	0.000	0.985	0.015
N39 Other disorders of urinary system	0.000	0.985	0.015
M86.8 Other osteomyelitis	0.000	0.985	0.015
M87 Osteonecrosis	0.000	0.985	0.015
M65.1 Other infective (teno)synovitis	0.000	0.985	0.015
M40-M43 Deforming dorsopathies	0.000	0.985	0.015
M15.4 Erosive (osteo)arthrosis	0.000	0.985	0.015
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.985	0.015
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.000	0.985	0.015
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.985	0.015
M89.03 Algoneurodystrophy (Forearm)	0.000	0.985	0.015
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.985	0.015
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.985	0.014
M19.27 Other secondary arthrosis (Ankle and foot)	0.000	0.985	0.014
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.985	0.015
M89.83 Other specified disorders of bone (Forearm)	0.000	0.985	0.014
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.986	0.014
M65.39 Trigger finger-Site unspec	0.000	0.986	0.014
M65.38 Trigger finger-Other	0.000	0.986	0.014
M65.37 Trigger finger-Ankle/foot	0.000	0.986	0.014
M65.36 Trigger finger-Lower leg	0.000	0.986	0.014
M65.35 Trigger finger-Pelvic/thigh	0.000	0.986	0.014
M65.33 Trigger finger-Forearm	0.000	0.986	0.014
M65.32 Trigger finger-Upper arm	0.000	0.986	0.014
M65.31 Trigger finger-Shldr region	0.000	0.986	0.014
M65.30 Trigger finger-Mult sites	0.000	0.986	0.014
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.000	0.986	0.014
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.986	0.014
M86.6 Other chronic osteomyelitis	0.000	0.986	0.014
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.000	0.986	0.014
M65.88 Other synovitis and tenosynovitis (Other)	0.000	0.986	0.014
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.000	0.986	0.014
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.000	0.986	0.014
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.000	0.986	0.014
M89.08 Algoneurodystrophy (Other)	0.000	0.986	0.014
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.000	0.986	0.014
M89.02 Algoneurodystrophy (Upper arm)	0.000	0.986	0.014

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations