TreeWAS – Variant ID: rs12731740

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80 Cholelithiasis	0.979	0.021	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.972	0.028	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.963	0.037	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.951	0.049	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.948	0.052	0.000
K83 Other diseases of biliary tract	0.938	0.062	0.000
K82 Other diseases of gallbladder	0.926	0.074	0.000
K83.8 Other specified diseases of biliary tract	0.916	0.084	0.000
K82.4 Cholesterolosis of gallbladder	0.896	0.104	0.000
K83.1 Obstruction of bile duct	0.869	0.131	0.000
K80.8 Other cholelithiasis	0.851	0.149	0.000
K82.2 Perforation of gallbladder	0.847	0.153	0.000
K80.4 Calculus of bile duct with cholecystitis	0.838	0.162	0.000
K86 Other diseases of pancreas	0.722	0.278	0.000
K80.3 Calculus of bile duct with cholangitis	0.702	0.298	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.682	0.318	0.000
K83.5 Biliary cyst	0.672	0.327	0.000
K83.4 Spasm of sphincter of Oddi	0.672	0.327	0.000
K83.3 Fistula of bile duct	0.672	0.327	0.000
K83.2 Perforation of bile duct	0.672	0.327	0.000
K82.0 Obstruction of gallbladder	0.664	0.336	0.000
K82.3 Fistula of gallbladder	0.658	0.342	0.000
K83.0 Cholangitis	0.649	0.351	0.000
K86.9 Disease of pancreas, unspecified	0.636	0.363	0.000
K82.9 Disease of gallbladder, unspecified	0.629	0.371	0.000
K82.8 Other specified diseases of gallbladder	0.610	0.390	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.597	0.403	0.000
K82.1 Hydrops of gallbladder	0.551	0.449	0.000
K86.8 Other specified diseases of pancreas	0.543	0.457	0.000
K83.9 Disease of biliary tract, unspecified	0.533	0.467	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.503	0.496	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.489	0.511	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.489	0.511	0.000
K86.3 Pseudocyst of pancreas	0.476	0.524	0.000
K85 Acute pancreatitis	0.466	0.534	0.000
K86.2 Cyst of pancreas	0.434	0.566	0.000
K85.8 Other acute pancreatitis	0.334	0.666	0.000
K85.3 Drug-induced acute pancreatitis	0.334	0.666	0.000
K85.0 Idiopathic acute pancreatitis	0.334	0.666	0.000
K85.2 Alcohol-induced acute pancreatitis	0.326	0.674	0.000
K86.1 Other chronic pancreatitis	0.293	0.707	0.000
K85.9 Acute pancreatitis, unspecified	0.263	0.737	0.000
K85.1 Biliary acute pancreatitis	0.254	0.746	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.216	0.784	0.000
K81 Cholecystitis	0.149	0.850	0.000
K81.8 Other cholecystitis	0.111	0.889	0.000
K81.9 Cholecystitis, unspecified	0.054	0.945	0.000
K81.0 Acute cholecystitis	0.051	0.949	0.000
K81.1 Chronic cholecystitis	0.030	0.969	0.000
D25.0 Submucous leiomyoma of uterus	0.028	0.972	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.021	0.979	0.000
D05.1 Intraductal carcinoma in situ	0.015	0.985	0.000
M75.5 Bursitis of shoulder	0.000	0.986	0.014
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.012	0.988	0.000
Chapter XI Diseases of the digestive system	0.012	0.988	0.000
K70-K77 Diseases of liver	0.011	0.989	0.000
M75.1 Rotator cuff syndrome	0.000	0.989	0.011
K13 Other diseases of lip and oral mucosa	0.011	0.989	0.000
K72 Hepatic failure, not elsewhere classified	0.010	0.990	0.000
M75 Shoulder lesions	0.000	0.990	0.010
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.990	0.010
D05 Carcinoma in situ of breast	0.010	0.990	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.990	0.010
N97.9 Female infertility, unspecified	0.000	0.991	0.009
K73 Chronic hepatitis, not elsewhere classified	0.009	0.991	0.000
K72.9 Hepatic failure, unspecified	0.009	0.991	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.009	0.991	0.000
K70 Alcoholic liver disease	0.009	0.991	0.000
K50-K52 Noninfective enteritis and colitis	0.009	0.991	0.000
K75 Other inflammatory liver diseases	0.009	0.991	0.000
K51 Ulcerative colitis	0.008	0.992	0.000
K72.1 Chronic hepatic failure	0.008	0.992	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.008	0.992	0.000
K70.0 Alcoholic fatty liver	0.008	0.992	0.000
K72.0 Acute and subacute hepatic failure	0.008	0.992	0.000
M75.3 Calcific tendinitis of shoulder	0.000	0.992	0.008
K51.9 Ulcerative colitis, unspecified	0.008	0.992	0.000
K73.9 Chronic hepatitis, unspecified	0.008	0.992	0.000
K77 Liver disorders in diseases classified elsewhere	0.008	0.992	0.000
K71 Toxic liver disease	0.008	0.992	0.000
K76 Other diseases of liver	0.008	0.992	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.008	0.992	0.000
K13.5 Oral submucous fibrosis	0.008	0.992	0.000
K13.3 Hairy leukoplakia	0.008	0.992	0.000
K13.1 Cheek and lip biting	0.008	0.992	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.008	0.992	0.000
K51.4 Pseudopolyposis of colon	0.008	0.992	0.000
K76.8 Other specified diseases of liver	0.008	0.992	0.000
K65-K67 Diseases of peritoneum	0.008	0.992	0.000
M75.2 Bicipital tendinitis	0.000	0.992	0.008
K70.2 Alcoholic fibrosis and sclerosis of liver	0.007	0.992	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.007	0.993	0.000
K57 Diverticular disease of intestine	0.007	0.993	0.000
M75.8 Other shoulder lesions	0.000	0.993	0.007
K75.8 Other specified inflammatory liver diseases	0.007	0.993	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.007	0.993	0.000
K35-K38 Diseases of appendix	0.007	0.993	0.000
D05.7 Other carcinoma in situ of breast	0.007	0.993	0.000
D25 Leiomyoma of uterus	0.007	0.993	0.000
D05.0 Lobular carcinoma in situ	0.007	0.993	0.000
K75.4 Autoimmune hepatitis	0.007	0.993	0.000
M51 Other intervertebral disk disorders	0.007	0.993	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.007	0.993	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.007	0.993	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.007	0.993	0.000
M51.2 Other specified intervertebral disk displacement	0.007	0.993	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.007	0.993	0.000
K35.8 Acute appendicitis, other and unspecified	0.007	0.993	0.000
K65.0 Acute peritonitis	0.007	0.993	0.000
K70.3 Alcoholic cirrhosis of liver	0.007	0.993	0.000
M75.0 Adhesive capsulitis of shoulder	0.000	0.993	0.007
K76.0 Fatty (change of) liver, not elsewhere classified	0.007	0.993	0.000
Z98.8 Other specified postsurgical states	0.007	0.993	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.006	0.993	0.000
K75.2 Nonspecific reactive hepatitis	0.006	0.993	0.000
K75.1 Phlebitis of portal vein	0.006	0.993	0.000
K50.1 Crohn's disease of large intestine	0.006	0.993	0.000
K65 Peritonitis	0.006	0.994	0.000
K74 Fibrosis and cirrhosis of liver	0.006	0.994	0.000
K50 Crohn's disease [regional enteritis]	0.006	0.994	0.000
M75.9 Shoulder lesion, unspecified	0.000	0.994	0.006
K70.1 Alcoholic hepatitis	0.006	0.994	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.006	0.994	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.006	0.994	0.000
M51.8 Other specified intervertebral disk disorders	0.006	0.994	0.000
H33.0 Retinal detachment with retinal break	0.000	0.994	0.006
K71.9 Toxic liver disease, unspecified	0.006	0.994	0.000
K71.8 Toxic liver disease with other disorders of liver	0.006	0.994	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.006	0.994	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.006	0.994	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.006	0.994	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.006	0.994	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.006	0.994	0.000
K71.2 Toxic liver disease with acute hepatitis	0.006	0.994	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.006	0.994	0.000
K71.0 Toxic liver disease with cholestasis	0.006	0.994	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.006	0.994	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
K51.5 Mucosal proctocolitis	0.006	0.994	0.000
K70.9 Alcoholic liver disease, unspecified	0.006	0.994	0.000
M50.3 Other cervical disk degeneration	0.006	0.994	0.000
K76.5 Hepatic veno-occlusive disease	0.006	0.994	0.000
K76.4 Peliosis hepatis	0.006	0.994	0.000
K76.3 Infarction of liver	0.006	0.994	0.000
K76.2 Central haemorrhagic necrosis of liver	0.006	0.994	0.000
K76.1 Chronic passive congestion of liver	0.006	0.994	0.000
K75.9 Inflammatory liver disease, unspecified	0.006	0.994	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.006	0.994	0.000
K74.5 Biliary cirrhosis, unspecified	0.006	0.994	0.000
D25.9 Leiomyoma of uterus, unspecified	0.006	0.994	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.006	0.994	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.006	0.994	0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.006	0.994	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.006	0.994	0.000
K13.0 Diseases of lips	0.006	0.994	0.000
Z98.1 Arthrodesis status	0.006	0.994	0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.005	0.994	0.000
K76.7 Hepatorenal syndrome	0.005	0.994	0.000
K35 Acute appendicitis	0.006	0.994	0.000
K75.0 Abscess of liver	0.005	0.994	0.000
M75.81 Other shoulder lesions, right shoulder	0.000	0.994	0.005
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.005	0.995	0.000
K51.2 Ulcerative (chronic) proctitis	0.005	0.995	0.000
M51.3 Other specified intervertebral disk degeneration	0.005	0.995	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.005	0.995	0.000
M51.4 Schmorl's nodes	0.005	0.995	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.005	0.995	0.000
K36 Other appendicitis	0.005	0.995	0.000
M50-M54 Other dorsopathies	0.005	0.995	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.005	0.995	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.005	0.995	0.000
M54.9 Dorsalgia, unspecified	0.005	0.995	0.000
K70.4 Alcoholic hepatic failure	0.005	0.995	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.995	0.005
K76.9 Liver disease, unspecified	0.005	0.995	0.000
M54 Dorsalgia	0.005	0.995	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.005	0.995	0.000
K74.4 Secondary biliary cirrhosis	0.005	0.995	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.005	0.995	0.000
K74.1 Hepatic sclerosis	0.005	0.995	0.000
K37 Unspecified appendicitis	0.005	0.995	0.000
M50 Cervical disk disorders	0.005	0.995	0.000
M54.2 Cervicalgia	0.005	0.995	0.000
K38 Other diseases of appendix	0.005	0.995	0.000
D25.2 Subserosal leiomyoma of uterus	0.005	0.995	0.000
N90.5 Atrophy of vulva	0.005	0.995	0.000
Z98 Other postsurgical states	0.005	0.995	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.995	0.005
M51.9 Intervertebral disk disorder, unspecified	0.004	0.995	0.000
K51.8 Other ulcerative colitis	0.004	0.995	0.000
C67.9 Bladder, unspecified	0.005	0.995	0.000
M54.29 Cervicalgia-Site unspe	0.004	0.996	0.000
K74.0 Hepatic fibrosis	0.004	0.996	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.004	0.996	0.000
K67.3 Tuberculous peritonitis	0.004	0.996	0.000
K67.2 Syphilitic peritonitis	0.004	0.996	0.000
K67.1 Gonococcal peritonitis	0.004	0.996	0.000
K67.0 Chlamydial peritonitis	0.004	0.996	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.004	0.996	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.004	0.996	0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.004	0.996	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.004	0.996	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.004	0.996	0.000
M54.22 Cervicalgia (Cervical region)	0.004	0.996	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.996	0.004
K65.8 Other peritonitis	0.004	0.996	0.000
K52 Other non-infective gastro-enteritis and colitis	0.004	0.996	0.000
M54.8 Other dorsalgia	0.004	0.996	0.000
K61.0 Anal abscess	0.004	0.996	0.000
K50.0 Crohn's disease of small intestine	0.004	0.996	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.004	0.996	0.000
K55-K64 Other diseases of intestines	0.004	0.996	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.004	0.996	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.004	0.996	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.004	0.996	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.004	0.996	0.000
M54.3 Sciatica	0.004	0.996	0.000
K61 Abscess of anal and rectal regions	0.004	0.996	0.000
M54.1 Radiculopathy	0.004	0.996	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.004	0.996	0.000
N97 Female infertility	0.000	0.996	0.004
M53 Other dorsopathies, not elsewhere classified	0.004	0.996	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.996	0.004
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.996	0.004
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.996	0.004
D04.4 Skin of scalp and neck	0.004	0.996	0.000
M50.9 Cervical disk disorder, unspecified	0.004	0.996	0.000
K40-K46 Hernia	0.004	0.996	0.000
K12.2 Cellulitis and abscess of mouth	0.004	0.996	0.000
M54.0 Panniculitis affecting regions of neck and back	0.004	0.996	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.004	0.996	0.000
K63.9 Disease of intestine, unspecified	0.004	0.996	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
K52.3 Indeterminate colitis	0.004	0.996	0.000
M50.8 Other cervical disk disorders	0.004	0.996	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.004	0.996	0.000
M54.27 Cervicalgia-Lumbosacral	0.004	0.996	0.000
M54.26 Cervicalgia-Lumbar	0.004	0.996	0.000
M54.25 Cervicalgia-Thoracolumbar	0.004	0.996	0.000
M54.24 Cervicalgia-Thoracic	0.004	0.996	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.004	0.996	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.004	0.996	0.000
M54.20 Cervicalgia-Mult site	0.004	0.996	0.000
M50.2 Other cervical disk displacement	0.004	0.996	0.000
K38.9 Disease of appendix, unspecified	0.003	0.996	0.000
K38.3 Fistula of appendix	0.003	0.996	0.000
K38.2 Diverticulum of appendix	0.003	0.996	0.000
K38.0 Hyperplasia of appendix	0.003	0.996	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.996	0.004
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.004	0.996	0.000
M54.12 Radiculopathy (Cervical region)	0.004	0.996	0.000
K38.1 Appendicular concretions	0.003	0.996	0.000
M54.37 Sciatica (Lumbosacral region)	0.004	0.996	0.000
M54.6 Pain in thoracic spine	0.004	0.996	0.000
K10 Other diseases of jaws	0.004	0.996	0.000
M54.19 Radiculopathy (Site unspecified)	0.004	0.996	0.000
M54.39 Sciatica (Site unspecified)	0.004	0.996	0.000
K35.3 Acute appendicitis with localized peritonitis	0.003	0.996	0.000
K66 Other disorders of peritoneum	0.004	0.996	0.000
K58 Irritable bowel syndrome	0.004	0.996	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.996	0.003
D00-D09 In situ neoplasms	0.004	0.996	0.000
K12 Stomatitis and related lesions	0.004	0.996	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.003	0.996	0.000
E06.3 Autoimmune thyroiditis	0.000	0.996	0.003
K50.9 Crohn's disease, unspecified	0.003	0.996	0.000
M54.89 Other dorsalgia (Site unspecified)	0.003	0.997	0.000
K65.9 Peritonitis, unspecified	0.003	0.997	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.003	0.997	0.000
M54.14 Radiculopathy (Thoracic region)	0.003	0.997	0.000
D04 Carcinoma in situ of skin	0.003	0.997	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.997	0.003
K52.1 Toxic gastro-enteritis and colitis	0.003	0.997	0.000
K50.8 Other Crohn's disease	0.003	0.997	0.000
K42 Umbilical hernia	0.003	0.997	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.003	0.997	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.003	0.997	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.997	0.003
K74.3 Primary biliary cirrhosis	0.003	0.997	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.003	0.997	0.000
J34.3 Hypertrophy of nasal turbinates	0.000	0.997	0.003
K10.2 Inflammatory conditions of jaws	0.003	0.997	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.003	0.997	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.003	0.997	0.000
M54.86 Other dorsalgia (Lumbar region)	0.003	0.997	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.003	0.997	0.000
M54.84 Other dorsalgia (Thoracic region)	0.003	0.997	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.003	0.997	0.000
M54.82 Other dorsalgia (Cervical region)	0.003	0.997	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.003	0.997	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.003	0.997	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.003	0.997	0.000
M54.35 Sciatica (Thoracolumbar region)	0.003	0.997	0.000
M54.34 Sciatica-Thoracic	0.003	0.997	0.000
M54.33 Sciatica-Cervicothoracic	0.003	0.997	0.000
M54.32 Sciatica-Cervical	0.003	0.997	0.000
M54.31 Sciatica-Occipit-atl-axl	0.003	0.997	0.000
M54.30 Sciatica (Multiple sites in spine)	0.003	0.997	0.000
K61.4 Intrasphincteric abscess	0.003	0.997	0.000
K61.3 Ischiorectal abscess	0.003	0.997	0.000
K61.2 Anorectal abscess	0.003	0.997	0.000
K45 Other abdominal hernia	0.003	0.997	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.003	0.997	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.003	0.997	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.003	0.997	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.003	0.997	0.000
K12.3 Oral mucositis (ulcerative)	0.003	0.997	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.997	0.003
K10.8 Other specified diseases of jaws	0.003	0.997	0.000
K61.1 Rectal abscess	0.003	0.997	0.000
D04.2 Skin of ear and external auricular canal	0.003	0.997	0.000
M53.9 Dorsopathy, unspecified	0.003	0.997	0.000
M53.8 Other specified dorsopathies	0.003	0.997	0.000
M53.2 Spinal instabilities	0.003	0.997	0.000
M53.1 Cervicobrachial syndrome	0.003	0.997	0.000
M53.0 Cervicocranial syndrome	0.003	0.997	0.000
N97.8 Female infertility of other origin	0.000	0.997	0.003
N97.4 Female infertility associated with male factors	0.000	0.997	0.003
N97.3 Female infertility of cervical origin	0.000	0.997	0.003
N97.2 Female infertility of uterine origin	0.000	0.997	0.003
N97.0 Female infertility associated with anovulation	0.000	0.997	0.003
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.997	0.003
K66.1 Haemoperitoneum	0.003	0.997	0.000
I86.8 Varicose veins of other specified sites	0.003	0.997	0.000
J30.1 Allergic rhinitis due to pollen	0.003	0.997	0.000
N97.1 Female infertility of tubal origin	0.000	0.997	0.003
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.003	0.997	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.003	0.997	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.003	0.997	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.003	0.997	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.003	0.997	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.003	0.997	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.003	0.997	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.003	0.997	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.003	0.997	0.000
K03 Other diseases of hard tissues of teeth	0.003	0.997	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.003	0.997	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.003	0.997	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.003	0.997	0.000
K38.8 Other specified diseases of appendix	0.003	0.997	0.000
T82.1 Mechanical complication of cardiac electronic device	0.003	0.997	0.000
K10.0 Developmental disorders of jaws	0.003	0.997	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.003	0.997	0.000
R17 Unspecified jaundice	0.003	0.997	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.997	0.003
K00 Disorders of tooth development and eruption	0.003	0.997	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.003	0.997	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M54.69 Pain in thoracic spine-Site unspe	0.003	0.997	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.003	0.997	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.003	0.997	0.000
M54.66 Pain in thoracic spine-Lumbar	0.003	0.997	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.003	0.997	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.003	0.997	0.000
M54.62 Pain in thoracic spine-Cervical	0.003	0.997	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.003	0.997	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.003	0.997	0.000
K10.9 Disease of jaws, unspecified	0.003	0.997	0.000
K10.3 Alveolitis of jaws	0.003	0.997	0.000
K10.1 Giant cell granuloma, central	0.003	0.997	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.003	0.997	0.000
K76.6 Portal hypertension	0.003	0.997	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.000	0.997	0.003
K52.0 Gastro-enteritis and colitis due to radiation	0.003	0.997	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.003	0.997	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.003	0.997	0.000
D04.5 Skin of trunk	0.003	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.003	0.997	0.000
K41 Femoral hernia	0.003	0.997	0.000
D09 Carcinoma in situ of other and unspecified sites	0.003	0.997	0.000
H33 Retinal detachments and breaks	0.000	0.997	0.003
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.003	0.997	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.997	0.003
D04.9 Skin, unspecified	0.003	0.997	0.000
D04.8 Skin of other sites	0.003	0.997	0.000
D04.1 Skin of eyelid, including canthus	0.003	0.997	0.000
D04.0 Skin of lip	0.003	0.997	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.003	0.997	0.000
M54.4 Lumbago with sciatica	0.003	0.997	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.002	0.997	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.003	0.997	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.997	0.003
K14 Diseases of tongue	0.003	0.997	0.000
D25.1 Intramural leiomyoma of uterus	0.003	0.997	0.000
M75.4 Impingement syndrome of shoulder	0.000	0.997	0.003
K42.1 Umbilical hernia with gangrene	0.003	0.997	0.000
K14.9 Disease of tongue, unspecified	0.003	0.997	0.000
K66.9 Disorder of peritoneum, unspecified	0.002	0.997	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.002	0.997	0.000
D00.0 Lip, oral cavity and pharynx	0.003	0.997	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.002	0.997	0.000
I86.1 Scrotal varices	0.003	0.997	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.003	0.997	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.003	0.997	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.997	0.002
K12.0 Recurrent oral aphthae	0.002	0.997	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.002	0.997	0.000
H33.4 Traction detachment of retina	0.000	0.997	0.003
K00.9 Disorder of tooth development, unspecified	0.002	0.997	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.002	0.997	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.002	0.997	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.002	0.997	0.000
K64.9 Haemorrhoids, unspecified	0.002	0.997	0.000
K64.8 Other specified haemorrhoids	0.002	0.997	0.000
K64.5 Perianal venous thrombosis	0.002	0.997	0.000
K64.4 Residual haemorrhoidal skin tags	0.002	0.997	0.000
K64.3 Fourth degree haemorrhoids	0.002	0.997	0.000
K64.2 Third degree haemorrhoids	0.002	0.997	0.000
K64.1 Second degree haemorrhoids	0.002	0.997	0.000
K64.0 First degree haemorrhoids	0.002	0.997	0.000
K45.1 Other specified abdominal hernia with gangrene	0.002	0.997	0.000
K63 Other diseases of intestine	0.003	0.997	0.000
M53.09 Cervicocranial syndrome-Site unspe	0.002	0.997	0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.002	0.997	0.000
M53.07 Cervicocranial syndrome-Lumbosacral	0.002	0.997	0.000
M53.06 Cervicocranial syndrome-Lumbar	0.002	0.997	0.000
M53.05 Cervicocranial syndrome-Thoracolumbar	0.002	0.997	0.000
M53.04 Cervicocranial syndrome-Thoracic	0.002	0.997	0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.002	0.997	0.000
M53.02 Cervicocranial syndrome (Cervical region)	0.002	0.997	0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.002	0.997	0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.002	0.997	0.000
M53.19 Cervicobrachial syndrome-Site unspe	0.002	0.997	0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.002	0.997	0.000
M53.17 Cervicobrachial syndrome-Lumbosacral	0.002	0.997	0.000
M53.16 Cervicobrachial syndrome-Lumbar	0.002	0.997	0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.002	0.997	0.000
M53.14 Cervicobrachial syndrome-Thoracic	0.002	0.997	0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.002	0.997	0.000
M53.12 Cervicobrachial syndrome (Cervical region)	0.002	0.997	0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.002	0.997	0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.002	0.997	0.000
M53.29 Spinal instabilities (Site unspecified)	0.002	0.997	0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M53.27 Spinal instabilities (Lumbosacral region)	0.002	0.997	0.000
M53.26 Spinal instabilities (Lumbar region)	0.002	0.997	0.000
M53.25 Spinal instabilities (Thoracolumbar region)	0.002	0.997	0.000
M53.24 Spinal instabilities (Thoracic region)	0.002	0.997	0.000
M53.23 Spinal instabilities (Cervicothoracic region)	0.002	0.997	0.000
M53.22 Spinal instabilities (Cervical region)	0.002	0.997	0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.002	0.997	0.000
M53.20 Spinal instabilities (Multiple sites in spine)	0.002	0.997	0.000
M53.89 Other specified dorsopathies (Site unspecified)	0.002	0.997	0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M53.87 Other specified dorsopathies (Lumbosacral region)	0.002	0.997	0.000
M53.86 Other specified dorsopathies (Lumbar region)	0.002	0.997	0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.002	0.997	0.000
M53.84 Other specified dorsopathies (Thoracic region)	0.002	0.997	0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.002	0.997	0.000
M53.82 Other specified dorsopathies (Cervical region)	0.002	0.997	0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.002	0.997	0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.002	0.997	0.000
M53.99 Dorsopathy, unspecified (Site unspecified)	0.002	0.997	0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.002	0.997	0.000
M53.96 Dorsopathy, unspecified (Lumbar region)	0.002	0.997	0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.002	0.997	0.000
M53.94 Dorsopathy, unspecified (Thoracic region)	0.002	0.997	0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.002	0.997	0.000
M53.92 Dorsopathy, unspecified (Cervical region)	0.002	0.997	0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.997	0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.002	0.997	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.000	0.997	0.002
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.997	0.002
K66.8 Other specified disorders of peritoneum	0.002	0.998	0.000
K46 Unspecified abdominal hernia	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
D04.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.002	0.998	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.002	0.998	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.002	0.998	0.000
K03.6 Deposits [accretions] on teeth	0.002	0.998	0.000
K03.5 Ankylosis of teeth	0.002	0.998	0.000
K03.4 Hypercementosis	0.002	0.998	0.000
K03.3 Pathological resorption of teeth	0.002	0.998	0.000
K03.2 Erosion of teeth	0.002	0.998	0.000
K03.1 Abrasion of teeth	0.002	0.998	0.000
K03.0 Excessive attrition of teeth	0.002	0.998	0.000
D00.2 Stomach	0.002	0.998	0.000
D00.1 Oesophagus	0.002	0.998	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.002	0.998	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.002	0.998	0.000
K06.0 Gingival recession	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.002	0.998	0.000
M50.0 Cervical disk disorder with myelopathy	0.002	0.998	0.000
T82.3 Mechanical complication of other vascular grafts	0.002	0.998	0.000
M65 Synovitis and tenosynovitis	0.000	0.998	0.002
K00.8 Other disorders of tooth development	0.002	0.998	0.000
K00.7 Teething syndrome	0.002	0.998	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.002	0.998	0.000
K00.4 Disturbances in tooth formation	0.002	0.998	0.000
K00.3 Mottled teeth	0.002	0.998	0.000
K00.2 Abnormalities of size and form of teeth	0.002	0.998	0.000
K00.1 Supernumerary teeth	0.002	0.998	0.000
K00.0 Anodontia	0.002	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
K06.1 Gingival enlargement	0.002	0.998	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations