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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12790383
log Bayes Factor = 9.27946
Chromosome 11   position 75,708,521  (GRCh37) Explore rs12790383 on Ensembl!
Variant rs12790383 is part of Cluster X0052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.998 0.002 0.000
M20-M25 Other joint disorders
0.992 0.008 0.000
Chapter V Mental and behavioural disorders
0.992 0.008 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.988 0.012 0.000
M50-M54 Other dorsopathies
0.987 0.013 0.000
E86 Volume depletion
0.982 0.018 0.000
Chapter XXI Factors influencing health status and contact with health services
0.974 0.026 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.972 0.028 0.000
E87.2 Acidosis
0.972 0.028 0.000
E87.5 Hyperkalaemia
0.970 0.030 0.000
M54 Dorsalgia
0.960 0.040 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.958 0.042 0.000
F30-F39 Mood [affective] disorders
0.954 0.046 0.000
E20-E35 Disorders of other endocrine glands
0.954 0.046 0.000
E87.7 Fluid overload
0.950 0.050 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.947 0.053 0.000
M35 Other systemic involvement of connective tissue
0.943 0.057 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.942 0.058 0.000
M24 Other specific joint derangements
0.941 0.059 0.000
M25 Other joint disorders, not elsewhere classified
0.939 0.061 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.938 0.062 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.933 0.067 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.926 0.074 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.921 0.079 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.921 0.079 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.917 0.083 0.000
T40.2 Other opioids
0.910 0.090 0.000
Chapter VIII Diseases of the ear and mastoid process
0.908 0.092 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.904 0.096 0.000
S20-S29 Injuries to the thorax
0.900 0.100 0.000
M45-M49 Spondylopathies
0.898 0.102 0.000
O26.8 Other specified pregnancy-related conditions
0.898 0.102 0.000
M50 Cervical disk disorders
0.896 0.104 0.000
S10-S19 Injuries to the neck
0.895 0.105 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.893 0.107 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.892 0.108 0.000
F31 Bipolar affective disorder
0.882 0.118 0.000
H90-H95 Other disorders of ear
0.881 0.119 0.000
T39.1 4-Aminophenol derivatives
0.878 0.122 0.000
M35.3 Polymyalgia rheumatica
0.878 0.122 0.000
M25.5 Pain in joint
0.878 0.122 0.000
M54.5 Low back pain
0.876 0.124 0.000
Chapter XX External causes of morbidity and mortality
0.876 0.124 0.000
Z33 Pregnant state, incidental
0.873 0.127 0.000
H90 Conductive and sensorineural hearing loss
0.871 0.129 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.867 0.133 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.866 0.134 0.000
S40-S49 Injuries to the shoulder and upper arm
0.865 0.135 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.865 0.135 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.864 0.136 0.000
Z60 Problems related to social environment
0.858 0.142 0.000
F10.1 Harmful use
0.853 0.147 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.852 0.148 0.000
F32 Depressive episode
0.852 0.148 0.000
M54.56 Low back pain (Lumbar region)
0.845 0.155 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.842 0.158 0.000
E89.0 Postprocedural hypothyroidism
0.840 0.160 0.000
M24.2 Disorder of ligament
0.840 0.160 0.000
Z34 Supervision of normal pregnancy
0.839 0.161 0.000
S80-S89 Injuries to the knee and lower leg
0.839 0.161 0.000
F31.9 Bipolar affective disorder, unspecified
0.835 0.165 0.000
S00-S09 Injuries to the head
0.833 0.167 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.830 0.170 0.000
S70-S79 Injuries to the hip and thigh
0.829 0.171 0.000
O36 Maternal care for other known or suspected foetal problems
0.824 0.176 0.000
Z36 Antenatal screening
0.824 0.176 0.000
M24.1 Other articular cartilage disorders
0.820 0.180 0.000
Z22 Carrier of infectious disease
0.820 0.180 0.000
E83 Disorders of mineral metabolism
0.820 0.180 0.000
H90.5 Sensorineural hearing loss, unspecified
0.819 0.181 0.000
O85-O92 Complications predominantly related to the puerperium
0.818 0.182 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.818 0.182 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.817 0.183 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.816 0.184 0.000
M86-M90 Other osteopathies
0.815 0.185 0.000
Z60.2 Living alone
0.814 0.186 0.000
T39.0 Salicylates
0.814 0.186 0.000
X60-X84 Intentional self-harm
0.813 0.187 0.000
M34 Systemic sclerosis
0.812 0.188 0.000
E87.0 Hyperosmolality and hypernatraemia
0.811 0.189 0.000
Z35 Supervision of high-risk pregnancy
0.810 0.190 0.000
M25.57 Pain in joint (Ankle and foot)
0.807 0.193 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.807 0.193 0.000
Chapter I Certain infectious and parasitic diseases
0.804 0.196 0.000
E23 Hypofunction and other disorders of pituitary gland
0.803 0.197 0.000
M35.0 Sicca syndrome [Sjogren]
0.798 0.202 0.000
F99-F99 Unspecified mental disorder
0.797 0.203 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.794 0.206 0.000
F32.9 Depressive episode, unspecified
0.793 0.207 0.000
M50.3 Other cervical disk degeneration
0.792 0.208 0.000
M47 Spondylosis
0.791 0.208 0.000
T79-T79 Certain early complications of trauma
0.791 0.209 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.791 0.209 0.000
F10.3 Withdrawal state
0.787 0.213 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.785 0.215 0.000
Z34.8 Supervision of other normal pregnancy
0.785 0.215 0.000
O36.8 Maternal care for other specified foetal problems
0.785 0.215 0.000
S12 Fracture of neck
0.783 0.217 0.000
M80-M85 Disorders of bone density and structure
0.781 0.219 0.000
S42 Fracture of shoulder and upper arm
0.778 0.222 0.000
M54.4 Lumbago with sciatica
0.778 0.222 0.000
O20 Haemorrhage in early pregnancy
0.774 0.226 0.000
Z63 Other problems related to primary support group, including family circumstances
0.773 0.227 0.000
F60-F69 Disorders of adult personality and behaviour
0.773 0.227 0.000
F10.0 Acute intoxication
0.772 0.228 0.000
M54.1 Radiculopathy
0.769 0.231 0.000
E89.2 Postprocedural hypoparathyroidism
0.768 0.232 0.000
T66-T78 Other and unspecified effects of external causes
0.766 0.234 0.000
E22 Hyperfunction of pituitary gland
0.764 0.236 0.000
M25.51 Pain in joint (Shoulder region)
0.763 0.237 0.000
Z31 Procreative management
0.763 0.237 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.763 0.237 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.760 0.240 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.758 0.242 0.000
E74 Other disorders of carbohydrate metabolism
0.758 0.242 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.758 0.242 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.755 0.245 0.000
Z22.3 Carrier of other specified bacterial diseases
0.754 0.246 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.753 0.246 0.000
M54.2 Cervicalgia
0.753 0.247 0.000
M30 Polyarteritis nodosa and related conditions
0.753 0.247 0.000
Z29 Need for other prophylactic measures
0.751 0.249 0.000
E21.0 Primary hyperparathyroidism
0.750 0.250 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.748 0.252 0.000
M60-M63 Disorders of muscles
0.747 0.253 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.746 0.254 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.744 0.256 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.743 0.257 0.000
E27 Other disorders of adrenal gland
0.743 0.257 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.742 0.258 0.000
S27 Injury of other and unspecified intrathoracic organs
0.742 0.258 0.000
S82 Fracture of lower leg, including ankle
0.742 0.258 0.000
E34 Other endocrine disorders
0.741 0.259 0.000
M50.1 Cervical disk disorder with radiculopathy
0.740 0.260 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.740 0.260 0.000
S09 Other and unspecified injuries of head
0.739 0.261 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.739 0.261 0.000
M40-M43 Deforming dorsopathies
0.739 0.261 0.000
M25.56 Pain in joint (Lower leg)
0.738 0.262 0.000
T18 Foreign body in alimentary tract
0.738 0.262 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.734 0.266 0.000
H90.0 Conductive hearing loss, bilateral
0.734 0.266 0.000
O28 Abnormal findings on antenatal screening of mother
0.732 0.268 0.000
S70 Superficial injury of hip and thigh
0.731 0.269 0.000
M54.6 Pain in thoracic spine
0.731 0.269 0.000
M47.2 Other spondylosis with radiculopathy
0.729 0.271 0.000
E73 Lactose intolerance
0.726 0.273 0.000
M54.3 Sciatica
0.726 0.274 0.000
M20 Acquired deformities of fingers and toes
0.726 0.274 0.000
M51 Other intervertebral disk disorders
0.725 0.275 0.000
S42.0 Fracture of clavicle
0.725 0.275 0.000
F30 Manic episode
0.725 0.275 0.000
M48 Other spondylopathies
0.723 0.277 0.000
O26.9 Pregnancy-related condition, unspecified
0.720 0.280 0.000
O00-O08 Pregnancy with abortive outcome
0.720 0.280 0.000
X62.9 Unspecified place
0.718 0.282 0.000
M24.0 Loose body in joint
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
M54.9 Dorsalgia, unspecified
0.716 0.284 0.000
B25-B34 Other viral diseases
0.716 0.284 0.000
E87.4 Mixed disorder of acid-base balance
0.715 0.284 0.000
F03 Unspecified dementia
0.714 0.286 0.000
E89.3 Postprocedural hypopituitarism
0.714 0.286 0.000
M25.8 Other specified joint disorders
0.713 0.287 0.000
M25.7 Osteophyte
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.288 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.711 0.289 0.000
F70-F79 Mental retardation
0.711 0.289 0.000
A30-A49 Other bacterial diseases
0.709 0.291 0.000
H90.3 Sensorineural hearing loss, bilateral
0.709 0.291 0.000
Q76 Congenital malformations of spine and bony thorax
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
M53 Other dorsopathies, not elsewhere classified
0.708 0.292 0.000
M49 Spondylopathies in diseases classified elsewhere
0.708 0.292 0.000
M91-M94 Chondropathies
0.706 0.294 0.000
Q80-Q89 Other congenital malformations
0.706 0.294 0.000
M25.52 Pain in joint (Upper arm)
0.705 0.295 0.000
Z64 Problems related to certain psychosocial circumstances
0.703 0.297 0.000
H90.2 Conductive hearing loss, unspecified
0.701 0.299 0.000
M47.8 Other spondylosis
0.701 0.299 0.000
E24 Cushing's syndrome
0.700 0.300 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.697 0.303 0.000
T39.4 Antirheumatics, not elsewhere classified
0.697 0.303 0.000
T39.2 Pyrazolone derivatives
0.697 0.303 0.000
O85 Puerperal sepsis
0.697 0.303 0.000
M25.3 Other instability of joint
0.696 0.304 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.693 0.307 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.693 0.307 0.000
B15-B19 Viral hepatitis
0.692 0.308 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.692 0.308 0.000
E87.3 Alkalosis
0.691 0.309 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.690 0.310 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.689 0.311 0.000
W50-W64 Exposure to animate mechanical forces
0.689 0.311 0.000
M24.21 Disorder of ligament (Shoulder region)
0.689 0.311 0.000
M54.8 Other dorsalgia
0.688 0.312 0.000
M54.0 Panniculitis affecting regions of neck and back
0.688 0.312 0.000
S42.00 Fracture of clavicle (closed)
0.688 0.312 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.688 0.312 0.000
F10.4 Withdrawal state with delirium
0.687 0.313 0.000
O29 Complications of anaesthesia during pregnancy
0.686 0.313 0.000
O22 Venous complications in pregnancy
0.686 0.313 0.000
O25 Malnutrition in pregnancy
0.686 0.313 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.685 0.315 0.000
F38 Other mood [affective] disorders
0.684 0.316 0.000
F34 Persistent mood [affective] disorders
0.684 0.316 0.000
F39 Unspecified mood [affective] disorder
0.684 0.316 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.684 0.316 0.000
E32 Diseases of thymus
0.684 0.316 0.000
E31 Polyglandular dysfunction
0.684 0.316 0.000
E30 Disorders of puberty, not elsewhere classified
0.684 0.316 0.000
E26 Hyperaldosteronism
0.684 0.316 0.000
E25 Adrenogenital disorders
0.684 0.316 0.000
E20 Hypoparathyroidism
0.684 0.316 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.683 0.316 0.000
O23 Infections of genito-urinary tract in pregnancy
0.682 0.318 0.000
Q50-Q56 Congenital malformations of genital organs
0.682 0.318 0.000
E21.3 Hyperparathyroidism, unspecified
0.682 0.318 0.000
M24.23 Disorder of ligament (Forearm)
0.681 0.319 0.000
E87.6 Hypokalaemia
0.680 0.320 0.000
E23.0 Hypopituitarism
0.680 0.320 0.000
W20-W49 Exposure to inanimate mechanical forces
0.679 0.321 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.679 0.321 0.000
T40.8 Lysergide [LSD]
0.679 0.321 0.000
T40.7 Cannabis (derivatives)
0.679 0.321 0.000
T40.6 Other and unspecified narcotics
0.679 0.321 0.000
T40.5 Cocaine
0.679 0.321 0.000
T40.4 Other synthetic narcotics
0.679 0.321 0.000
T40.3 Methadone
0.679 0.321 0.000
T40.1 Heroin
0.679 0.321 0.000
T40.0 Opium
0.679 0.321 0.000
S50-S59 Injuries to the elbow and forearm
0.678 0.322 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.678 0.322 0.000
E65-E68 Obesity and other hyperalimentation
0.676 0.324 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.676 0.324 0.000
M35.8 Other specified systemic involvement of connective tissue
0.676 0.324 0.000
M35.7 Hypermobility syndrome
0.676 0.324 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.676 0.324 0.000
M35.5 Multifocal fibrosclerosis
0.676 0.324 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.676 0.324 0.000
M35.2 Behcet's disease
0.676 0.324 0.000
M35.1 Other overlap syndromes
0.676 0.324 0.000
Z38 Liveborn infants according to place of birth
0.675 0.325 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.675 0.325 0.000
M24.9 Joint derangement, unspecified
0.675 0.325 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.675 0.325 0.000
M24.7 Protrusio acetabuli
0.675 0.325 0.000
M24.6 Ankylosis of joint
0.675 0.325 0.000
M24.5 Contracture of joint
0.675 0.325 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.675 0.325 0.000
T17 Foreign body in respiratory tract
0.674 0.325 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.674 0.326 0.000
Q00-Q07 Congenital malformations of the nervous system
0.674 0.326 0.000
M25.9 Joint disorder, unspecified
0.673 0.327 0.000
M25.2 Flail joint
0.673 0.327 0.000
M25.1 Fistula of joint
0.673 0.327 0.000
M25.0 Haemarthrosis
0.673 0.327 0.000
E83.5 Disorders of calcium metabolism
0.673 0.327 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.672 0.328 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.672 0.328 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.672 0.328 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.672 0.328 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.672 0.328 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.672 0.328 0.000
F11 Mental and behavioural disorders due to use of opioids
0.672 0.328 0.000
S20 Superficial injury of thorax
0.672 0.328 0.000
F00 Dementia in Alzheimer's disease
0.670 0.330 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.669 0.331 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.669 0.331 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.669 0.331 0.000
E89.5 Postprocedural testicular hypofunction
0.669 0.331 0.000
E89.4 Postprocedural ovarian failure
0.669 0.331 0.000
E89.1 Postprocedural hypoinsulinaemia
0.669 0.331 0.000
M24.26 Disorder of ligament (Lower leg)
0.669 0.331 0.000
O16 Unspecified maternal hypertension
0.668 0.332 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.668 0.332 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.668 0.332 0.000
M21 Other acquired deformities of limbs
0.668 0.332 0.000
F10.2 Dependence syndrome
0.665 0.335 0.000
S29 Other and unspecified injuries of thorax
0.665 0.335 0.000
M31 Other necrotising vasculopathies
0.664 0.336 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.664 0.336 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.664 0.336 0.000
O26.5 Maternal hypotension syndrome
0.664 0.336 0.000
O26.4 Herpes gestationis
0.664 0.336 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.664 0.336 0.000
O26.2 Pregnancy care of habitual aborter
0.664 0.336 0.000
O26.1 Low weight gain in pregnancy
0.664 0.336 0.000
O26.0 Excessive weight gain in pregnancy
0.664 0.336 0.000
S09.9 Unspecified injury of head
0.664 0.336 0.000
S22.4 Multiple fractures of ribs
0.663 0.337 0.000
T51 Toxic effect of alcohol
0.662 0.338 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.662 0.338 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.662 0.338 0.000
O21 Excessive vomiting in pregnancy
0.661 0.338 0.000
Z35.8 Supervision of other high-risk pregnancies
0.661 0.339 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.661 0.339 0.000
T50.8 Diagnostic agents
0.660 0.340 0.000
T50.7 Analeptics and opioid receptor antagonists
0.660 0.340 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.660 0.340 0.000
T50.5 Appetite depressants
0.660 0.340 0.000
T50.4 Drugs affecting uric acid metabolism
0.660 0.340 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.660 0.340 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.660 0.340 0.000
T50.1 Loop [high-ceiling] diuretics
0.660 0.340 0.000
T50.0 Mineralocorticoids and their antagonists
0.660 0.340 0.000
Z65 Problems related to other psychosocial circumstances
0.660 0.340 0.000
Z62 Other problems related to upbringing
0.660 0.340 0.000
Z61 Problems related to negative life events in childhood
0.660 0.340 0.000
Z59 Problems related to housing and economic circumstances
0.660 0.340 0.000
Z58 Problems related to physical environment
0.660 0.340 0.000
Z56 Problems related to employment and unemployment
0.660 0.340 0.000
Z55 Problems related to education and literacy
0.660 0.340 0.000
O24 Diabetes mellitus in pregnancy
0.660 0.340 0.000
T42.4 Benzodiazepines
0.659 0.341 0.000
M54.59 Low back pain (Site unspecified)
0.659 0.341 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.659 0.341 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.659 0.341 0.000
F99 Mental disorder, not otherwise specified
0.657 0.343 0.000
F10.9 Unspecified mental and behavioural disorder
0.657 0.343 0.000
F10.8 Other mental and behavioural disorders
0.657 0.343 0.000
F10.7 Residual and late-onset psychotic disorder
0.657 0.343 0.000
F10.6 Amnesic syndrome
0.657 0.343 0.000
F10.5 Psychotic disorder
0.657 0.343 0.000
M84 Disorders of continuity of bone
0.656 0.344 0.000
M86 Osteomyelitis
0.656 0.344 0.000
M46 Other inflammatory spondylopathies
0.655 0.345 0.000
F80-F89 Disorders of psychological development
0.655 0.345 0.000
M50.0 Cervical disk disorder with myelopathy
0.654 0.346 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.653 0.347 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.653 0.347 0.000
X50-X57 Overexertion, travel and privation
0.653 0.347 0.000
Z39 Postpartum care and examination
0.652 0.348 0.000
Z74 Problems related to care-provider dependency
0.652 0.348 0.000
Z32 Pregnancy examination and test
0.652 0.348 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.649 0.351 0.000
M34.9 Systemic sclerosis, unspecified
0.649 0.351 0.000
Z28 Immunisation not carried out
0.648 0.352 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.648 0.352 0.000
Z26 Need for immunisation against other single infectious diseases
0.648 0.352 0.000
Z25 Need for immunisation against other single viral diseases
0.648 0.352 0.000
Z24 Need for immunisation against certain single viral diseases
0.648 0.352 0.000
Z23 Need for immunisation against single bacterial diseases
0.648 0.352 0.000
Z20 Contact with and exposure to communicable diseases
0.648 0.352 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.648 0.352 0.000
T18.1 Foreign body in oesophagus
0.648 0.352 0.000
S82.3 Fracture of lower end of tibia
0.647 0.353 0.000
M25.54 Pain in joint (Hand)
0.647 0.353 0.000
H93 Other disorders of ear, not elsewhere classified
0.647 0.353 0.000
M51.2 Other specified intervertebral disk displacement
0.646 0.354 0.000
S00 Superficial injury of head
0.645 0.355 0.000
S82.8 Fractures of other parts of lower leg
0.645 0.355 0.000
O41 Other disorders of amniotic fluid and membranes
0.645 0.355 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.645 0.355 0.000
S26 Injury of heart
0.645 0.355 0.000
S25 Injury of blood vessels of thorax
0.645 0.355 0.000
S24 Injury of nerves and spinal cord at thorax level
0.645 0.355 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.645 0.355 0.000
S21 Open wound of thorax
0.645 0.355 0.000
F33 Recurrent depressive disorder
0.644 0.355 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.643 0.357 0.000
Chapter XXII Codes for special purposes
0.643 0.357 0.000
M50.9 Cervical disk disorder, unspecified
0.642 0.357 0.000
M50.8 Other cervical disk disorders
0.642 0.357 0.000
H60-H62 Diseases of external ear
0.642 0.358 0.000
S17 Crushing injury of neck
0.642 0.358 0.000
S15 Injury of blood vessels at neck level
0.642 0.358 0.000
S14 Injury of nerves and spinal cord at neck level
0.642 0.358 0.000
S11 Open wound of neck
0.642 0.358 0.000
S10 Superficial injury of neck
0.642 0.358 0.000
S18 Traumatic amputation at neck level
0.642 0.358 0.000
S16 Injury of muscle and tendon at neck level
0.642 0.358 0.000
E22.0 Acromegaly and pituitary gigantism
0.641 0.359 0.000
Z29.0 Isolation
0.641 0.359 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.641 0.359 0.000
Q76.0 Spina bifida occulta
0.641 0.359 0.000
M22 Disorders of patella
0.641 0.359 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.640 0.360 0.000
E83.4 Disorders of magnesium metabolism
0.640 0.360 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.640 0.360 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.640 0.360 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.640 0.360 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.640 0.360 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.640 0.360 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.640 0.360 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.640 0.360 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.640 0.360 0.000
T44.0 Anticholinesterase agents
0.640 0.360 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.640 0.360 0.000
Q35-Q37 Cleft lip and cleft palate
0.640 0.360 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.640 0.360 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.640 0.360 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.639 0.361 0.000
O30 Multiple gestation
0.639 0.361 0.000
Z73 Problems related to life-management difficulty
0.638 0.362 0.000
B65-B83 Helminthiases
0.638 0.362 0.000
S90-S99 Injuries to the ankle and foot
0.637 0.362 0.000
S80 Superficial injury of lower leg
0.637 0.363 0.000
M87 Osteonecrosis
0.637 0.363 0.000
O40 Polyhydramnios
0.635 0.365 0.000
V80-V89 Other land transport accidents
0.635 0.365 0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation
0.635 0.365 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.634 0.366 0.000
S42.4 Fracture of lower end of humerus
0.633 0.367 0.000
F31.8 Other bipolar affective disorders
0.632 0.368 0.000
F31.7 Bipolar affective disorder, currently in remission
0.632 0.368 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.632 0.368 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.632 0.368 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.632 0.368 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.632 0.368 0.000
O36.6 Maternal care for excessive foetal growth
0.632 0.368 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.632 0.368 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.632 0.368 0.000
Z75 Problems related to medical facilities and other health care
0.632 0.368 0.000
M34.1 CR(E)ST syndrome
0.631 0.369 0.000
O47 False labour
0.631 0.369 0.000
Z63.4 Disappearance and death of family member
0.631 0.369 0.000
O36.5 Maternal care for poor foetal growth
0.631 0.369 0.000
Z35.5 Supervision of elderly primigravida
0.630 0.370 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.630 0.370 0.000
S41 Open wound of shoulder and upper arm
0.630 0.370 0.000
M25.59 Pain in joint (Site unspecified)
0.629 0.371 0.000
M25.58 Pain in joint (Other)
0.629 0.371 0.000
E29 Testicular dysfunction
0.629 0.371 0.000
E28 Ovarian dysfunction
0.629 0.371 0.000
S19 Other and unspecified injuries of neck
0.629 0.371 0.000
B25 Cytomegaloviral disease
0.628 0.372 0.000
S12.9 Fracture of neck, part unspecified
0.628 0.372 0.000
M54.55 Low back pain (Thoracolumbar region)
0.628 0.372 0.000
M54.54 Low back pain-Thoracic
0.628 0.372 0.000
M54.53 Low back pain-Cervicothoracic
0.628 0.372 0.000
M54.52 Low back pain-Cervical
0.628 0.372 0.000
M54.51 Low back pain-Occipit-atl-axl
0.628 0.372 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.628 0.372 0.000
Y35-Y36 Legal intervention and operations of war
0.628 0.372 0.000
Y10-Y34 Event of undetermined intent
0.628 0.372 0.000
Y00-Y09 Assault
0.628 0.372 0.000
X85-X99 Assault
0.628 0.372 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.628 0.372 0.000
X30-X39 Exposure to forces of nature
0.628 0.372 0.000
X20-X29 Contact with venomous animals and plants
0.628 0.372 0.000
X10-X19 Contact with heat and hot substances
0.628 0.372 0.000
X00-X09 Exposure to smoke, fire and flames
0.628 0.372 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.628 0.372 0.000
W75-W84 Other accidental threats to breathing
0.628 0.372 0.000
W65-W74 Accidental drowning and submersion
0.628 0.372 0.000
V98-V99 Other and unspecified transport accidents
0.628 0.372 0.000
V95-V97 Air and space transport accidents
0.628 0.372 0.000
V90-V94 Water transport accidents
0.628 0.372 0.000
V70-V79 Bus occupant injured in transport accident
0.628 0.372 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.628 0.372 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.628 0.372 0.000
V40-V49 Car occupant injured in transport accident
0.628 0.372 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.628 0.372 0.000
V01-V09 Pedestrian injured in transport accident
0.628 0.372 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.628 0.372 0.000
M50.2 Other cervical disk displacement
0.628 0.372 0.000
S12.2 Fracture of other specified cervical vertebra
0.627 0.373 0.000
T58 Toxic effect of carbon monoxide
0.626 0.374 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.624 0.376 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.624 0.376 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.624 0.376 0.000
S81 Open wound of lower leg
0.624 0.376 0.000
O36.4 Maternal care for intra-uterine death
0.624 0.376 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.624 0.376 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.624 0.376 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.623 0.377 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.623 0.377 0.000
O15 Eclampsia
0.622 0.378 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.622 0.378 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.622 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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