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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12823357
log Bayes Factor = 6.08625
Chromosome 12   position 55,473,859  (GRCh37) Explore rs12823357 on Ensembl!
Variant rs12823357 is part of Cluster X0101

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M24 Other specific joint derangements
0.996 0.004 0.000
M20 Acquired deformities of fingers and toes
0.996 0.004 0.000
M80-M85 Disorders of bone density and structure
0.994 0.006 0.000
M15-M19 Arthrosis
0.993 0.007 0.000
M20.5 Other deformities of toe(s) (acquired)
0.992 0.008 0.000
M17 Gonarthrosis [arthrosis of knee]
0.990 0.010 0.000
M17.9 Gonarthrosis, unspecified
0.989 0.011 0.000
M05-M14 Inflammatory polyarthropathies
0.988 0.012 0.000
M24.1 Other articular cartilage disorders
0.985 0.015 0.000
M81 Osteoporosis without pathological fracture
0.985 0.015 0.000
M65-M68 Disorders of synovium and tendon
0.985 0.015 0.000
M13 Other arthritis
0.981 0.019 0.000
M13.9 Arthritis, unspecified
0.976 0.024 0.000
M81.9 Osteoporosis, unspecified
0.973 0.027 0.000
M65 Synovitis and tenosynovitis
0.971 0.029 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.958 0.042 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.952 0.048 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.948 0.052 0.000
M21 Other acquired deformities of limbs
0.947 0.053 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.937 0.063 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.917 0.083 0.000
M19 Other arthrosis
0.915 0.085 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.912 0.088 0.000
M20.1 Hallux valgus (acquired)
0.908 0.092 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.905 0.095 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.903 0.097 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.902 0.098 0.000
M19.9 Arthrosis, unspecified
0.886 0.114 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.873 0.127 0.000
M21.0 Valgus deformity, not elsewhere classified
0.872 0.128 0.000
M85 Other disorders of bone density and structure
0.864 0.136 0.000
M25 Other joint disorders, not elsewhere classified
0.864 0.136 0.000
M05 Seropositive rheumatoid arthritis
0.855 0.145 0.000
M81.4 Drug-induced osteoporosis
0.838 0.162 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.837 0.163 0.000
M21.1 Varus deformity, not elsewhere classified
0.830 0.170 0.000
M91-M94 Chondropathies
0.828 0.172 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.823 0.177 0.000
M17.5 Other secondary gonarthrosis
0.819 0.181 0.000
M24.2 Disorder of ligament
0.816 0.184 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.815 0.185 0.000
M17.0 Primary gonarthrosis, bilateral
0.811 0.189 0.000
M24.0 Loose body in joint
0.798 0.202 0.000
M13.93 Arthritis, unspecified (Forearm)
0.797 0.203 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.794 0.206 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.789 0.211 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.780 0.220 0.000
M22 Disorders of patella
0.774 0.226 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.770 0.230 0.000
M33 Dermatopolymyositis
0.769 0.231 0.000
M60-M63 Disorders of muscles
0.767 0.233 0.000
M82 Osteoporosis in diseases classified elsewhere
0.765 0.234 0.000
M85.8 Other specified disorders of bone density and structure
0.764 0.236 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.763 0.237 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.760 0.240 0.000
M67 Other disorders of synovium and tendon
0.759 0.241 0.000
M65.3 Trigger finger
0.758 0.242 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.758 0.242 0.000
M25.3 Other instability of joint
0.753 0.247 0.000
M25.8 Other specified joint disorders
0.753 0.247 0.000
M34 Systemic sclerosis
0.753 0.247 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.749 0.251 0.000
M00-M03 Infectious arthropathies
0.747 0.253 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.743 0.256 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.743 0.257 0.000
M15 Polyarthrosis
0.741 0.259 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.741 0.259 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.732 0.268 0.000
M13.0 Polyarthritis, unspecified
0.726 0.274 0.000
M65.8 Other synovitis and tenosynovitis
0.723 0.277 0.000
M86-M90 Other osteopathies
0.722 0.278 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.722 0.278 0.000
M66 Spontaneous rupture of synovium and tendon
0.721 0.279 0.000
M19.98 Arthrosis, unspecified (Other)
0.718 0.282 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M25.7 Osteophyte
0.717 0.283 0.000
M24.9 Joint derangement, unspecified
0.714 0.286 0.000
M24.7 Protrusio acetabuli
0.714 0.286 0.000
M24.6 Ankylosis of joint
0.714 0.286 0.000
M24.5 Contracture of joint
0.714 0.286 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.714 0.286 0.000
M65.1 Other infective (teno)synovitis
0.714 0.286 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.713 0.286 0.000
M07 Psoriatic and enteropathic arthropathies
0.713 0.287 0.000
M83 Adult osteomalacia
0.712 0.288 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.710 0.290 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.710 0.290 0.000
M14 Arthropathies in other diseases classified elsewhere
0.709 0.291 0.000
M12 Other specific arthropathies
0.709 0.291 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.291 0.000
M08 Juvenile arthritis
0.709 0.291 0.000
M24.26 Disorder of ligament (Lower leg)
0.708 0.292 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.707 0.293 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.706 0.293 0.000
M24.18 Other articular cartilage disorders (Other)
0.706 0.293 0.000
M24.14 Other articular cartilage disorders (Hand)
0.706 0.293 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.706 0.293 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.706 0.293 0.000
M81.8 Other osteoporosis
0.706 0.294 0.000
M81.6 Localised osteoporosis [Lequesne]
0.706 0.294 0.000
M81.5 Idiopathic osteoporosis
0.706 0.294 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.706 0.294 0.000
M81.2 Osteoporosis of disuse
0.706 0.294 0.000
M81.1 Postoophorectomy osteoporosis
0.706 0.294 0.000
M81.0 Postmenopausal osteoporosis
0.706 0.294 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.706 0.294 0.000
M13.8 Other specified arthritis
0.704 0.296 0.000
M13.1 Monoarthritis, not elsewhere classified
0.704 0.296 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.702 0.298 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.701 0.299 0.000
M21.3 Wrist or foot drop (acquired)
0.698 0.302 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.698 0.302 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.698 0.302 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.698 0.302 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.698 0.302 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.698 0.302 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.698 0.302 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.697 0.303 0.000
M65.2 Calcific tendinitis
0.696 0.304 0.000
M65.0 Abscess of tendon sheath
0.696 0.304 0.000
M19.1 Posttraumatic arthrosis of other joints
0.692 0.308 0.000
M40-M43 Deforming dorsopathies
0.692 0.308 0.000
M80 Osteoporosis with pathological fracture
0.688 0.312 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.686 0.314 0.000
M21.2 Flexion deformity
0.685 0.315 0.000
M45-M49 Spondylopathies
0.685 0.315 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.684 0.316 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.683 0.317 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.683 0.317 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.683 0.317 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.683 0.317 0.000
M81.98 Osteoporosis, unspecified (Other)
0.682 0.318 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.682 0.318 0.000
M24.02 Loose body in joint (Upper arm)
0.680 0.320 0.000
M21.9 Acquired deformity of limb, unspecified
0.679 0.321 0.000
M21.8 Other specified acquired deformities of limbs
0.679 0.321 0.000
M21.7 Unequal limb length (acquired)
0.679 0.321 0.000
M21.4 Flat foot [pes planus] (acquired)
0.679 0.321 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.679 0.321 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.676 0.323 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.669 0.331 0.000
M11 Other crystal arthropathies
0.666 0.333 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.665 0.335 0.000
M13.98 Arthritis, unspecified (Other)
0.664 0.336 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.663 0.337 0.000
M93 Other osteochondropathies
0.658 0.342 0.000
M19.8 Other specified arthrosis
0.656 0.344 0.000
M19.2 Other secondary arthrosis
0.656 0.344 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.654 0.346 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.653 0.347 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.646 0.353 0.000
M25.37 Other instability of joint (Ankle and foot)
0.645 0.355 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.641 0.359 0.000
M85.0 Fibrous dysplasia (monostotic)
0.638 0.362 0.000
M25.9 Joint disorder, unspecified
0.632 0.368 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.631 0.369 0.000
M21.6 Other acquired deformities of ankle and foot
0.630 0.369 0.000
M94 Other disorders of cartilage
0.630 0.370 0.000
M20.2 Hallux rigidus
0.629 0.371 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.628 0.372 0.000
M84 Disorders of continuity of bone
0.628 0.372 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.625 0.375 0.000
M21.08 Valgus deformity, not elsewhere classified (Other)
0.625 0.375 0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.625 0.375 0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.625 0.375 0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.625 0.375 0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.625 0.375 0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.625 0.375 0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.625 0.375 0.000
M25.4 Effusion of joint
0.624 0.376 0.000
M10 Gout
0.624 0.376 0.000
M25.84 Other specified joint disorders (Hand)
0.621 0.379 0.000
M85.9 Disorder of bone density and structure, unspecified
0.620 0.380 0.000
M85.6 Other cyst of bone
0.620 0.380 0.000
M85.5 Aneurysmal bone cyst
0.620 0.380 0.000
M85.4 Solitary bone cyst
0.620 0.380 0.000
M85.3 Osteitis condensans
0.620 0.380 0.000
M85.2 Hyperostosis of skull
0.620 0.380 0.000
M85.1 Skeletal fluorosis
0.620 0.380 0.000
M25.2 Flail joint
0.619 0.381 0.000
M25.1 Fistula of joint
0.619 0.381 0.000
M25.77 Osteophyte (Ankle and foot)
0.613 0.387 0.000
M05.8 Other seropositive rheumatoid arthritis
0.613 0.387 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.613 0.387 0.000
M05.2 Rheumatoid vasculitis
0.613 0.387 0.000
M05.1 Rheumatoid lung disease
0.613 0.387 0.000
M05.0 Felty's syndrome
0.613 0.387 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.610 0.390 0.000
M23 Internal derangement of knee
0.609 0.391 0.000
M65.34 Trigger finger-Hand
0.606 0.394 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.604 0.396 0.000
M33.1 Other dermatomyositis
0.603 0.397 0.000
M82.1 Osteoporosis in endocrine disorders
0.602 0.398 0.000
M20.3 Other deformity of hallux (acquired)
0.601 0.399 0.000
M24.23 Disorder of ligament (Forearm)
0.601 0.399 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.601 0.399 0.000
M81.48 Drug-induced osteoporosis (Other)
0.601 0.399 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.601 0.399 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.601 0.399 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.601 0.399 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.601 0.399 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.601 0.399 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.601 0.399 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.601 0.399 0.000
M24.24 Disorder of ligament (Hand)
0.600 0.400 0.000
M62 Other disorders of muscle
0.600 0.400 0.000
M25.36 Other instability of joint (Lower leg)
0.598 0.402 0.000
M17.3 Other posttraumatic gonarthrosis
0.595 0.404 0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.595 0.405 0.000
M21.18 Varus deformity, not elsewhere classified (Other)
0.595 0.405 0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.595 0.405 0.000
M21.14 Varus deformity, not elsewhere classified (Hand)
0.595 0.405 0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.595 0.405 0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.595 0.405 0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.595 0.405 0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.595 0.405 0.000
M92 Other juvenile osteochondrosis
0.594 0.406 0.000
M22.4 Chondromalacia patellae
0.588 0.412 0.000
M24.29 Disorder of ligament (Site unspecified)
0.585 0.415 0.000
M24.28 Disorder of ligament (Other)
0.585 0.415 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.585 0.415 0.000
M24.22 Disorder of ligament (Upper arm)
0.585 0.415 0.000
M24.21 Disorder of ligament (Shoulder region)
0.585 0.415 0.000
M24.20 Disorder of ligament (Multiple sites)
0.585 0.415 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.584 0.416 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.584 0.416 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.584 0.416 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.584 0.416 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.584 0.416 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.584 0.416 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.584 0.416 0.000
M34.1 CR(E)ST syndrome
0.582 0.418 0.000
M22.3 Other derangements of patella
0.580 0.420 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.580 0.420 0.000
M67.1 Other contracture of tendon (sheath)
0.579 0.421 0.000
M24.09 Loose body in joint (Site unspecified)
0.572 0.428 0.000
M24.08 Loose body in joint (Other)
0.572 0.428 0.000
M24.06 Loose body in joint-Lower leg
0.572 0.428 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.572 0.428 0.000
M24.04 Loose body in joint (Hand)
0.572 0.428 0.000
M24.03 Loose body in joint (Forearm)
0.572 0.428 0.000
M24.01 Loose body in joint (Shoulder region)
0.572 0.428 0.000
M24.00 Loose body in joint (Multiple sites)
0.572 0.428 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.572 0.428 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.571 0.428 0.000
M25.83 Other specified joint disorders (Forearm)
0.571 0.429 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.567 0.433 0.000
M00 Pyogenic arthritis
0.565 0.435 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.565 0.435 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.560 0.439 0.000
M25.0 Haemarthrosis
0.560 0.440 0.000
M89 Other disorders of bone
0.559 0.441 0.000
M22.2 Patellofemoral disorders
0.559 0.441 0.000
M50-M54 Other dorsopathies
0.558 0.442 0.000
M22.1 Recurrent subluxation of patella
0.555 0.445 0.000
M22.9 Disorder of patella, unspecified
0.555 0.445 0.000
M22.0 Recurrent dislocation of patella
0.555 0.445 0.000
M22.8 Other disorders of patella
0.555 0.445 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.555 0.445 0.000
M33.9 Dermatopolymyositis, unspecified
0.551 0.449 0.000
M33.2 Polymyositis
0.551 0.449 0.000
M33.0 Juvenile dermatomyositis
0.551 0.449 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.550 0.450 0.000
M61 Calcification and ossification of muscle
0.550 0.450 0.000
M60 Myositis
0.550 0.450 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.549 0.451 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.549 0.451 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.549 0.451 0.000
M46 Other inflammatory spondylopathies
0.549 0.451 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.548 0.452 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.548 0.452 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.548 0.452 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.548 0.452 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.548 0.452 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.548 0.452 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.548 0.452 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.548 0.452 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.545 0.455 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.545 0.455 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.545 0.455 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.545 0.455 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.545 0.455 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.545 0.455 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.545 0.455 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.545 0.455 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.544 0.455 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.544 0.455 0.000
M67.4 Ganglion
0.544 0.455 0.000
M67.3 Transient synovitis
0.544 0.455 0.000
M67.0 Short Achilles tendon (acquired)
0.544 0.455 0.000
M65.39 Trigger finger-Site unspec
0.544 0.456 0.000
M65.38 Trigger finger-Other
0.544 0.456 0.000
M65.37 Trigger finger-Ankle/foot
0.544 0.456 0.000
M65.36 Trigger finger-Lower leg
0.544 0.456 0.000
M65.35 Trigger finger-Pelvic/thigh
0.544 0.456 0.000
M65.33 Trigger finger-Forearm
0.544 0.456 0.000
M65.32 Trigger finger-Upper arm
0.544 0.456 0.000
M65.31 Trigger finger-Shldr region
0.544 0.456 0.000
M65.30 Trigger finger-Mult sites
0.544 0.456 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.543 0.457 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.543 0.457 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.543 0.457 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.543 0.457 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.543 0.457 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.543 0.457 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.543 0.457 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.543 0.457 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.542 0.458 0.000
M25.39 Other instability of joint (Site unspecified)
0.540 0.460 0.000
M25.38 Other instability of joint (Other)
0.540 0.460 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.540 0.460 0.000
M25.34 Other instability of joint (Hand)
0.540 0.460 0.000
M25.33 Other instability of joint (Forearm)
0.540 0.460 0.000
M25.32 Other instability of joint (Upper arm)
0.540 0.460 0.000
M25.31 Other instability of joint (Shoulder region)
0.540 0.460 0.000
M25.30 Other instability of joint (Multiple sites)
0.540 0.460 0.000
M88 Paget's disease of bone [osteitis deformans]
0.540 0.460 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.540 0.460 0.000
M25.88 Other specified joint disorders (Other)
0.540 0.460 0.000
M25.82 Other specified joint disorders (Upper arm)
0.540 0.460 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.540 0.460 0.000
M34.8 Other forms of systemic sclerosis
0.540 0.460 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.540 0.460 0.000
M34.0 Progressive systemic sclerosis
0.540 0.460 0.000
M35 Other systemic involvement of connective tissue
0.539 0.461 0.000
M40 Kyphosis and lordosis
0.539 0.461 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.538 0.462 0.000
M93.9 Osteochondropathy, unspecified
0.536 0.464 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.535 0.464 0.000
M02 Reactive arthropathies
0.535 0.464 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.535 0.464 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.535 0.464 0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.532 0.468 0.000
M48 Other spondylopathies
0.532 0.468 0.000
M15.9 Polyarthrosis, unspecified
0.531 0.469 0.000
M15.0 Primary generalised (osteo)arthrosis
0.531 0.469 0.000
M15.8 Other polyarthrosis
0.531 0.469 0.000
M15.4 Erosive (osteo)arthrosis
0.531 0.469 0.000
M15.3 Secondary multiple arthrosis
0.531 0.469 0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.531 0.469 0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.531 0.469 0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.531 0.469 0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.531 0.469 0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.531 0.469 0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.531 0.469 0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.531 0.469 0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.531 0.469 0.000
M34.9 Systemic sclerosis, unspecified
0.531 0.469 0.000
M65.14 Other infective (teno)synovitis (Hand)
0.530 0.470 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.529 0.471 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.528 0.472 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.526 0.474 0.000
M90 Osteopathies in diseases classified elsewhere
0.526 0.474 0.000
M24.07 Loose body in joint (Ankle and foot)
0.525 0.475 0.000
M66.0 Rupture of popliteal cyst
0.525 0.475 0.000
M66.2 Spontaneous rupture of extensor tendons
0.525 0.475 0.000
M15.1 Heberden's nodes (with arthropathy)
0.524 0.476 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.522 0.478 0.000
M13.08 Polyarthritis, unspecified (Other)
0.521 0.479 0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)
0.521 0.479 0.000
M13.06 Polyarthritis, unspecified (Lower leg)
0.521 0.479 0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)
0.521 0.479 0.000
M13.04 Polyarthritis, unspecified (Hand)
0.521 0.479 0.000
M13.03 Polyarthritis, unspecified (Forearm)
0.521 0.479 0.000
M13.02 Polyarthritis, unspecified (Upper arm)
0.521 0.479 0.000
M13.01 Polyarthritis, unspecified (Shoulder region)
0.521 0.479 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.520 0.480 0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)
0.518 0.482 0.000
M65.88 Other synovitis and tenosynovitis (Other)
0.518 0.482 0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)
0.518 0.482 0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)
0.518 0.482 0.000
M65.83 Other synovitis and tenosynovitis (Forearm)
0.518 0.482 0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)
0.518 0.482 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.518 0.482 0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)
0.518 0.482 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.517 0.483 0.000
M66.4 Spontaneous rupture of other tendons
0.517 0.483 0.000
M66.3 Spontaneous rupture of flexor tendons
0.517 0.483 0.000
M66.1 Rupture of synovium
0.517 0.483 0.000
M07.3 Other psoriatic arthropathies
0.515 0.485 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.514 0.486 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.514 0.486 0.000
M30.2 Juvenile polyarteritis
0.514 0.486 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.514 0.486 0.000
M30.0 Polyarteritis nodosa
0.514 0.486 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.514 0.486 0.000
M32.8 Other forms of systemic lupus erythematosus
0.514 0.486 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.514 0.486 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.514 0.486 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.514 0.486 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.514 0.486 0.000
M36.3 Arthropathy in other blood disorders
0.514 0.486 0.000
M36.2 Haemophilic arthropathy
0.514 0.486 0.000
M36.1 Arthropathy in neoplastic disease
0.514 0.486 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.514 0.486 0.000
M25.79 Osteophyte (Site unspecified)
0.514 0.486 0.000
M25.73 Osteophyte (Forearm)
0.514 0.486 0.000
M25.70 Osteophyte (Multiple sites)
0.514 0.486 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.512 0.488 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.512 0.488 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.512 0.488 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.512 0.488 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.512 0.488 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.512 0.488 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.512 0.488 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.512 0.488 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.512 0.488 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.512 0.488 0.000
M24.59 Contracture of joint (Site unspecified)
0.512 0.488 0.000
M24.58 Contracture of joint (Other)
0.512 0.488 0.000
M24.57 Contracture of joint (Ankle and foot)
0.512 0.488 0.000
M24.56 Contracture of joint (Lower leg)
0.512 0.488 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.512 0.488 0.000
M24.54 Contracture of joint (Hand)
0.512 0.488 0.000
M24.53 Contracture of joint (Forearm)
0.512 0.488 0.000
M24.52 Contracture of joint (Upper arm)
0.512 0.488 0.000
M24.51 Contracture of joint (Shoulder region)
0.512 0.488 0.000
M24.50 Contracture of joint (Multiple sites)
0.512 0.488 0.000
M24.69 Ankylosis of joint (Site unspecified)
0.512 0.488 0.000
M24.68 Ankylosis of joint (Other)
0.512 0.488 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.512 0.488 0.000
M24.66 Ankylosis of joint (Lower leg)
0.512 0.488 0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)
0.512 0.488 0.000
M24.64 Ankylosis of joint (Hand)
0.512 0.488 0.000
M24.63 Ankylosis of joint (Forearm)
0.512 0.488 0.000
M24.62 Ankylosis of joint (Upper arm)
0.512 0.488 0.000
M24.61 Ankylosis of joint (Shoulder region)
0.512 0.488 0.000
M24.60 Ankylosis of joint (Multiple sites)
0.512 0.488 0.000
M24.79 Protrusio acetabuli-Site unspec
0.512 0.488 0.000
M24.78 Protrusio acetabuli-Other
0.512 0.488 0.000
M24.77 Protrusio acetabuli-Ankle/foot
0.512 0.488 0.000
M24.76 Protrusio acetabuli-Lower leg
0.512 0.488 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.512 0.488 0.000
M24.74 Protrusio acetabuli-Hand
0.512 0.488 0.000
M24.73 Protrusio acetabuli-Forearm
0.512 0.488 0.000
M24.72 Protrusio acetabuli-Upper arm
0.512 0.488 0.000
M24.71 Protrusio acetabuli-Shldr region
0.512 0.488 0.000
M24.70 Protrusio acetabuli-Mult sites
0.512 0.488 0.000
M24.99 Joint derangement, unspecified (Site unspecified)
0.512 0.488 0.000
M24.98 Joint derangement, unspecified (Other)
0.512 0.488 0.000
M24.97 Joint derangement, unspecified (Ankle and foot)
0.512 0.488 0.000
M24.96 Joint derangement, unspecified (Lower leg)
0.512 0.488 0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)
0.512 0.488 0.000
M24.94 Joint derangement, unspecified (Hand)
0.512 0.488 0.000
M24.93 Joint derangement, unspecified (Forearm)
0.512 0.488 0.000
M24.92 Joint derangement, unspecified (Upper arm)
0.512 0.488 0.000
M24.91 Joint derangement, unspecified (Shoulder region)
0.512 0.488 0.000
M24.90 Joint derangement, unspecified (Multiple sites)
0.512 0.488 0.000
M65.19 Other infective (teno)synovitis (Site unspecified)
0.512 0.488 0.000
M65.18 Other infective (teno)synovitis (Other)
0.512 0.488 0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.512 0.488 0.000
M65.16 Other infective (teno)synovitis (Lower leg)
0.512 0.488 0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.512 0.488 0.000
M65.13 Other infective (teno)synovitis (Forearm)
0.512 0.488 0.000
M65.12 Other infective (teno)synovitis (Upper arm)
0.512 0.488 0.000
M65.11 Other infective (teno)synovitis (Shoulder region)
0.512 0.488 0.000
M65.10 Other infective (teno)synovitis (Multiple sites)
0.512 0.488 0.000
M07.6 Other enteropathic arthropathies
0.511 0.489 0.000
M07.5 Arthropathy in ulcerative colitis
0.511 0.489 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.511 0.489 0.000
M07.2 Psoriatic spondylitis
0.511 0.489 0.000
M07.1 Arthritis mutilans
0.511 0.489 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.511 0.489 0.000
M83.9 Adult osteomalacia, unspecified
0.511 0.489 0.000
M83.8 Other adult osteomalacia
0.511 0.489 0.000
M83.5 Other drug-induced osteomalacia in adults
0.511 0.489 0.000
M83.4 Aluminum bone disease
0.511 0.489 0.000
M83.3 Adult osteomalacia due to malnutrition
0.511 0.489 0.000
M83.2 Adult osteomalacia due to malabsorption
0.511 0.489 0.000
M83.1 Senile osteomalacia
0.511 0.489 0.000
M83.0 Puerperal osteomalacia
0.511 0.489 0.000
M08.9 Juvenile arthritis, unspecified
0.508 0.492 0.000
M08.8 Other juvenile arthritis
0.508 0.492 0.000
M08.4 Pauciarticular juvenile arthritis
0.508 0.492 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.508 0.492 0.000
M08.2 Juvenile arthritis with systemic onset
0.508 0.492 0.000
M08.1 Juvenile ankylosing spondylitis
0.508 0.492 0.000
M08.0 Juvenile rheumatoid arthritis
0.508 0.492 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.508 0.492 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.508 0.492 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.508 0.492 0.000
M09.0 Juvenile arthritis in psoriasis
0.508 0.492 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.508 0.492 0.000
M12.5 Traumatic arthropathy
0.508 0.492 0.000
M12.4 Intermittent hydrarthrosis
0.508 0.492 0.000
M12.3 Palindromic rheumatism
0.508 0.492 0.000
M12.2 Villonodular synovitis (pigmented)
0.508 0.492 0.000
M12.1 Kaschin-Beck disease
0.508 0.492 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.508 0.492 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.508 0.492 0.000
M14.6 Neuropathic arthropathy
0.508 0.492 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.508 0.492 0.000
M14.4 Arthropathy in amyloidosis
0.508 0.492 0.000
M14.3 Lipoid dermatoarthritis
0.508 0.492 0.000
M14.2 Diabetic arthropathy
0.508 0.492 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.508 0.492 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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