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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1291837
log Bayes Factor = 11.8934
Chromosome 10   position 11,101,682  (GRCh37) Explore rs1291837 on Ensembl!
Variant rs1291837 is part of Cluster X0224

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
N20-N23 Urolithiasis
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
Chapter XI Diseases of the digestive system
0.996 0.004 0.000
E10-E14 Diabetes mellitus
0.995 0.005 0.000
Chapter IX Diseases of the circulatory system
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
N20 Calculus of kidney and ureter
0.992 0.008 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.989 0.011 0.000
E11 Non-insulin-dependent diabetes mellitus
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.986 0.014 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.985 0.015 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.985 0.015 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.985 0.015 0.000
N10-N16 Renal tubulo-interstitial diseases
0.977 0.023 0.000
H40-H42 Glaucoma
0.977 0.023 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.972 0.028 0.000
C15-C26 Malignant neoplasms of digestive organs
0.971 0.029 0.000
N20.1 Calculus of ureter
0.971 0.029 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.966 0.034 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.964 0.036 0.000
N13 Obstructive and reflux uropathy
0.962 0.038 0.000
H40 Glaucoma
0.960 0.040 0.000
H52 Disorders of refraction and accommodation
0.959 0.041 0.000
E14 Unspecified diabetes mellitus
0.957 0.043 0.000
I73 Other peripheral vascular diseases
0.952 0.048 0.000
D10-D36 Benign neoplasms
0.940 0.060 0.000
E11.9 Without complications
0.939 0.061 0.000
F10.1 Harmful use
0.937 0.063 0.000
C64-C68 Malignant neoplasms of urinary tract
0.935 0.065 0.000
F10.0 Acute intoxication
0.932 0.068 0.000
C18 Malignant neoplasm of colon
0.929 0.071 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.929 0.071 0.000
Chapter VIII Diseases of the ear and mastoid process
0.929 0.071 0.000
I60-I69 Cerebrovascular diseases
0.925 0.075 0.000
I73.9 Peripheral vascular disease, unspecified
0.925 0.075 0.000
K86 Other diseases of pancreas
0.923 0.077 0.000
D17 Benign lipomatous neoplasm
0.922 0.078 0.000
K40-K46 Hernia
0.922 0.078 0.000
E14.9 Without complications
0.915 0.085 0.000
H40.1 Primary open-angle glaucoma
0.913 0.087 0.000
H52.2 Astigmatism
0.909 0.091 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.908 0.092 0.000
K70-K77 Diseases of liver
0.907 0.093 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.906 0.094 0.000
E20-E35 Disorders of other endocrine glands
0.905 0.095 0.000
E11.3 With ophthalmic complications
0.903 0.097 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.902 0.098 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.902 0.098 0.000
H52.1 Myopia
0.900 0.100 0.000
N20.9 Urinary calculus, unspecified
0.899 0.101 0.000
I77 Other disorders of arteries and arterioles
0.898 0.102 0.000
H65-H75 Diseases of middle ear and mastoid
0.896 0.104 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.891 0.109 0.000
F10.2 Dependence syndrome
0.890 0.110 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.889 0.111 0.000
K81 Cholecystitis
0.885 0.115 0.000
K86.8 Other specified diseases of pancreas
0.884 0.116 0.000
D12.6 Colon, unspecified
0.883 0.117 0.000
K90-K93 Other diseases of the digestive system
0.879 0.121 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.877 0.123 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.876 0.124 0.000
C18.0 Caecum
0.876 0.124 0.000
I63 Cerebral infarction
0.873 0.127 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.873 0.127 0.000
N23 Unspecified renal colic
0.873 0.127 0.000
K42 Umbilical hernia
0.871 0.129 0.000
C79 Secondary malignant neoplasm of other sites
0.869 0.131 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.859 0.141 0.000
D12.5 Sigmoid colon
0.857 0.143 0.000
K81.1 Chronic cholecystitis
0.855 0.145 0.000
H25-H28 Disorders of lens
0.852 0.148 0.000
C78.2 Secondary malignant neoplasm of pleura
0.851 0.149 0.000
K83 Other diseases of biliary tract
0.850 0.150 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.850 0.150 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.849 0.151 0.000
H72 Perforation of tympanic membrane
0.848 0.152 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.846 0.154 0.000
H43-H45 Disorders of vitreous body and globe
0.844 0.156 0.000
N17-N19 Renal failure
0.834 0.166 0.000
I63.9 Cerebral infarction, unspecified
0.830 0.170 0.000
K41 Femoral hernia
0.826 0.174 0.000
H40.0 Glaucoma suspect
0.826 0.174 0.000
K86.9 Disease of pancreas, unspecified
0.822 0.178 0.000
N00-N08 Glomerular diseases
0.820 0.180 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.820 0.180 0.000
I30-I52 Other forms of heart disease
0.820 0.180 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.819 0.181 0.000
K76 Other diseases of liver
0.819 0.181 0.000
H55-H59 Other disorders of eye and adnexa
0.813 0.187 0.000
F99-F99 Unspecified mental disorder
0.812 0.188 0.000
C20 Malignant neoplasm of rectum
0.812 0.188 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.811 0.189 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.807 0.193 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.805 0.195 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.805 0.195 0.000
N20.2 Calculus of kidney with calculus of ureter
0.804 0.196 0.000
C80 Malignant neoplasm without specification of site
0.803 0.197 0.000
E11.2 With renal complications
0.800 0.200 0.000
D36 Benign neoplasm of other and unspecified sites
0.799 0.200 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.799 0.201 0.000
H10-H13 Disorders of conjunctiva
0.799 0.201 0.000
Q60-Q64 Congenital malformations of the urinary system
0.798 0.202 0.000
E11.4 With neurological complications
0.793 0.207 0.000
D32 Benign neoplasm of meninges
0.792 0.208 0.000
I72 Other aneurysm
0.792 0.208 0.000
Y95 Nosocomial condition
0.792 0.208 0.000
N13.4 Hydroureter
0.791 0.209 0.000
C16 Malignant neoplasm of stomach
0.789 0.211 0.000
K90 Intestinal malabsorption
0.787 0.213 0.000
Chapter XXII Codes for special purposes
0.786 0.214 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.785 0.215 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.785 0.215 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.784 0.216 0.000
H40.9 Glaucoma, unspecified
0.783 0.217 0.000
N20.0 Calculus of kidney
0.783 0.217 0.000
I77.1 Stricture of artery
0.781 0.219 0.000
I05-I09 Chronic rheumatic heart diseases
0.780 0.220 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.780 0.220 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.779 0.221 0.000
K46 Unspecified abdominal hernia
0.779 0.221 0.000
D00-D09 In situ neoplasms
0.778 0.222 0.000
C78.0 Secondary malignant neoplasm of lung
0.778 0.222 0.000
E14.3 With ophthalmic complications
0.775 0.225 0.000
F10.4 Withdrawal state with delirium
0.775 0.225 0.000
H49 Paralytic strabismus
0.775 0.225 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.774 0.226 0.000
H71 Cholesteatoma of middle ear
0.774 0.226 0.000
H25 Senile cataract
0.773 0.227 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.772 0.228 0.000
H30-H36 Disorders of choroid and retina
0.769 0.231 0.000
I71 Aortic aneurysm and dissection
0.769 0.231 0.000
C79.6 Secondary malignant neoplasm of ovary
0.768 0.232 0.000
C18.4 Transverse colon
0.768 0.232 0.000
E11.5 With peripheral circulatory complications
0.767 0.233 0.000
V80-V89 Other land transport accidents
0.767 0.233 0.000
H52.3 Anisometropia and aniseikonia
0.767 0.233 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.766 0.233 0.000
N13.6 Pyonephrosis
0.762 0.237 0.000
E11.0 With coma
0.762 0.238 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.761 0.238 0.000
E50-E64 Other nutritional deficiencies
0.761 0.239 0.000
H25.9 Senile cataract, unspecified
0.761 0.239 0.000
Q50-Q56 Congenital malformations of genital organs
0.761 0.239 0.000
Y85 Sequelae of transport accidents
0.759 0.241 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.758 0.242 0.000
I78 Diseases of capillaries
0.757 0.243 0.000
I77.8 Other specified disorders of arteries and arterioles
0.757 0.243 0.000
I51 Complications and ill-defined descriptions of heart disease
0.756 0.244 0.000
Y40 Systemic antibiotics
0.756 0.244 0.000
I35 Nonrheumatic aortic valve disorders
0.753 0.247 0.000
I69 Sequelae of cerebrovascular disease
0.752 0.248 0.000
C18.7 Sigmoid colon
0.751 0.249 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.751 0.249 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.750 0.250 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.749 0.250 0.000
N21 Calculus of lower urinary tract
0.749 0.251 0.000
E10 Insulin-dependent diabetes mellitus
0.749 0.251 0.000
F60-F69 Disorders of adult personality and behaviour
0.748 0.252 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.748 0.252 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.748 0.252 0.000
F41 Other anxiety disorders
0.748 0.252 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.748 0.252 0.000
H90-H95 Other disorders of ear
0.747 0.253 0.000
Y83.4 Other reconstructive surgery
0.745 0.255 0.000
D18 Haemangioma and lymphangioma, any site
0.742 0.258 0.000
H43 Disorders of vitreous body
0.742 0.258 0.000
F80-F89 Disorders of psychological development
0.741 0.259 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.740 0.260 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.738 0.262 0.000
H69 Other disorders of Eustachian tube
0.738 0.262 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.736 0.264 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.734 0.266 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.733 0.267 0.000
K70 Alcoholic liver disease
0.733 0.267 0.000
N99-N99 Other disorders of the genitourinary system
0.733 0.267 0.000
E24 Cushing's syndrome
0.733 0.267 0.000
V40-V49 Car occupant injured in transport accident
0.732 0.268 0.000
H40.5 Glaucoma secondary to other eye disorders
0.732 0.268 0.000
I10-I15 Hypertensive diseases
0.732 0.268 0.000
W50-W64 Exposure to animate mechanical forces
0.731 0.269 0.000
H36 Retinal disorders in diseases classified elsewhere
0.731 0.269 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.730 0.270 0.000
I70 Atherosclerosis
0.728 0.272 0.000
I77.0 Arteriovenous fistula, acquired
0.728 0.272 0.000
K90.0 Coeliac disease
0.725 0.275 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.725 0.275 0.000
C51-C58 Malignant neoplasms of female genital organs
0.724 0.276 0.000
E40-E46 Malnutrition
0.722 0.278 0.000
K83.1 Obstruction of bile duct
0.722 0.278 0.000
I46 Cardiac arrest
0.721 0.279 0.000
I73.0 Raynaud's syndrome
0.720 0.280 0.000
K65-K67 Diseases of peritoneum
0.719 0.281 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.719 0.281 0.000
N40-N51 Diseases of male genital organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Q61 Cystic kidney disease
0.717 0.283 0.000
Y52 Agents primarily affecting the cardiovascular system
0.716 0.284 0.000
N18 Chronic renal failure
0.716 0.284 0.000
X60-X84 Intentional self-harm
0.716 0.284 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.714 0.285 0.000
E13 Other specified diabetes mellitus
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.714 0.286 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
E22 Hyperfunction of pituitary gland
0.713 0.287 0.000
H40.2 Primary angle-closure glaucoma
0.713 0.287 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.711 0.289 0.000
C21 Malignant neoplasm of anus and anal canal
0.711 0.289 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.711 0.289 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.710 0.290 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.710 0.290 0.000
K75 Other inflammatory liver diseases
0.709 0.291 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.709 0.291 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.709 0.291 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.709 0.291 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.709 0.291 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.709 0.291 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.709 0.291 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.709 0.291 0.000
F11 Mental and behavioural disorders due to use of opioids
0.709 0.291 0.000
D12.8 Rectum
0.709 0.291 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.709 0.291 0.000
E11.8 With unspecified complications
0.709 0.291 0.000
E11.7 With multiple complications
0.709 0.291 0.000
E11.6 With other specified complications
0.709 0.291 0.000
E11.1 With ketoacidosis
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
Y00-Y09 Assault
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.293 0.000
X50-X57 Overexertion, travel and privation
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
I51.8 Other ill-defined heart diseases
0.707 0.293 0.000
I35.1 Aortic (valve) insufficiency
0.706 0.293 0.000
F10.9 Unspecified mental and behavioural disorder
0.706 0.294 0.000
F10.8 Other mental and behavioural disorders
0.706 0.294 0.000
F10.7 Residual and late-onset psychotic disorder
0.706 0.294 0.000
F10.6 Amnesic syndrome
0.706 0.294 0.000
F10.5 Psychotic disorder
0.706 0.294 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.706 0.294 0.000
H36.0 Diabetic retinopathy
0.704 0.296 0.000
N25-N29 Other disorders of kidney and ureter
0.704 0.296 0.000
I62 Other nontraumatic intracranial haemorrhage
0.703 0.297 0.000
C18.3 Hepatic flexure
0.703 0.297 0.000
D30 Benign neoplasm of urinary organs
0.702 0.298 0.000
Y83.0 Surgical operation with transplant of whole organ
0.701 0.299 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.700 0.299 0.000
N15 Other renal tubulo-interstitial diseases
0.700 0.299 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.700 0.299 0.000
H42 Glaucoma in diseases classified elsewhere
0.700 0.300 0.000
C78.7 Secondary malignant neoplasm of liver
0.700 0.300 0.000
H57 Other disorders of eye and adnexa
0.699 0.301 0.000
Y44 Agents primarily affecting blood constituents
0.698 0.302 0.000
N11 Chronic tubulo-interstitial nephritis
0.698 0.302 0.000
H51 Other disorders of binocular movement
0.697 0.303 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.696 0.304 0.000
C17 Malignant neoplasm of small intestine
0.696 0.304 0.000
C23 Malignant neoplasm of gallbladder
0.696 0.304 0.000
Q00-Q07 Congenital malformations of the nervous system
0.695 0.304 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.695 0.305 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.695 0.305 0.000
Y83.8 Other surgical procedures
0.694 0.306 0.000
C18.6 Descending colon
0.693 0.307 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.692 0.307 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.692 0.307 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.692 0.307 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.692 0.308 0.000
K50-K52 Noninfective enteritis and colitis
0.691 0.309 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.691 0.309 0.000
N13.8 Other obstructive and reflux uropathy
0.691 0.309 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.690 0.310 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.690 0.310 0.000
H40.8 Other glaucoma
0.689 0.311 0.000
H40.6 Glaucoma secondary to drugs
0.689 0.311 0.000
H40.4 Glaucoma secondary to eye inflammation
0.689 0.311 0.000
H40.3 Glaucoma secondary to eye trauma
0.689 0.311 0.000
H52.7 Disorder of refraction, unspecified
0.688 0.312 0.000
H52.6 Other disorders of refraction
0.688 0.312 0.000
H52.5 Disorders of accommodation
0.688 0.312 0.000
H52.4 Presbyopia
0.688 0.312 0.000
E23 Hypofunction and other disorders of pituitary gland
0.688 0.312 0.000
Y85.0 Sequelae of motor-vehicle accident
0.687 0.313 0.000
K83.8 Other specified diseases of biliary tract
0.687 0.313 0.000
E14.8 With unspecified complications
0.686 0.314 0.000
E14.7 With multiple complications
0.686 0.314 0.000
E14.6 With other specified complications
0.686 0.314 0.000
E14.5 With peripheral circulatory complications
0.686 0.314 0.000
E14.4 With neurological complications
0.686 0.314 0.000
E14.2 Withrenal complications
0.686 0.314 0.000
E14.1 With ketoacidosis
0.686 0.314 0.000
E14.0 With coma
0.686 0.314 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.686 0.314 0.000
K55-K64 Other diseases of intestines
0.685 0.315 0.000
I73.8 Other specified peripheral vascular diseases
0.683 0.317 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.683 0.317 0.000
E21.0 Primary hyperparathyroidism
0.683 0.317 0.000
N10 Acute tubulo-interstitial nephritis
0.682 0.318 0.000
Q80-Q89 Other congenital malformations
0.681 0.319 0.000
F99 Mental disorder, not otherwise specified
0.681 0.319 0.000
I12 Hypertensive renal disease
0.678 0.322 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.678 0.322 0.000
F17.2 Dependence syndrome
0.678 0.322 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.678 0.322 0.000
K73 Chronic hepatitis, not elsewhere classified
0.677 0.323 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.677 0.323 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.676 0.324 0.000
I63.8 Other cerebral infarction
0.676 0.324 0.000
K86.2 Cyst of pancreas
0.675 0.325 0.000
D31 Benign neoplasm of eye and adnexa
0.674 0.326 0.000
D29 Benign neoplasm of male genital organs
0.674 0.326 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.674 0.326 0.000
D19 Benign neoplasm of mesothelial tissue
0.674 0.326 0.000
D16 Benign neoplasm of bone and articular cartilage
0.674 0.326 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.674 0.326 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.673 0.327 0.000
I61 Intracerebral haemorrhage
0.672 0.328 0.000
F43 Reaction to severe stress, and adjustment disorders
0.672 0.328 0.000
E21.3 Hyperparathyroidism, unspecified
0.672 0.328 0.000
K02 Dental caries
0.672 0.328 0.000
K76.7 Hepatorenal syndrome
0.671 0.329 0.000
H27 Other disorders of lens
0.671 0.329 0.000
I67 Other cerebrovascular diseases
0.671 0.329 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.671 0.329 0.000
C66 Malignant neoplasm of ureter
0.671 0.329 0.000
C65 Malignant neoplasm of renal pelvis
0.671 0.329 0.000
Y57 Other and unspecified drugs and medicaments
0.670 0.330 0.000
H65 Nonsuppurative otitis media
0.668 0.332 0.000
E65-E68 Obesity and other hyperalimentation
0.668 0.332 0.000
K35-K38 Diseases of appendix
0.667 0.333 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.666 0.333 0.000
C18.8 Overlapping lesion of colon
0.666 0.334 0.000
C18.1 Appendix
0.666 0.334 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.666 0.334 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.666 0.334 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.666 0.334 0.000
Q35-Q37 Cleft lip and cleft palate
0.666 0.334 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.666 0.334 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.666 0.334 0.000
I08 Multiple valve diseases
0.665 0.335 0.000
F41.2 Mixed anxiety and depressive disorder
0.664 0.336 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.663 0.336 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.663 0.337 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.663 0.337 0.000
D11 Benign neoplasm of major salivary glands
0.663 0.337 0.000
I72.8 Aneurysm of other specified arteries
0.663 0.337 0.000
E53 Deficiency of other B group vitamins
0.662 0.338 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.661 0.339 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.661 0.339 0.000
D32.0 Cerebral meninges
0.661 0.339 0.000
K45 Other abdominal hernia
0.661 0.339 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.660 0.340 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.659 0.341 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.659 0.341 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.659 0.341 0.000
C60-C63 Malignant neoplasms of male genital organs
0.659 0.341 0.000
I65.2 Occlusion and stenosis of carotid artery
0.653 0.347 0.000
C79.2 Secondary malignant neoplasm of skin
0.652 0.348 0.000
C16.0 Cardia
0.652 0.348 0.000
K85 Acute pancreatitis
0.650 0.349 0.000
K77 Liver disorders in diseases classified elsewhere
0.650 0.350 0.000
K71 Toxic liver disease
0.650 0.350 0.000
D12.9 Anus and anal canal
0.649 0.350 0.000
D12.1 Appendix
0.649 0.350 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.649 0.351 0.000
E34 Other endocrine disorders
0.649 0.351 0.000
E32 Diseases of thymus
0.649 0.351 0.000
E31 Polyglandular dysfunction
0.649 0.351 0.000
E30 Disorders of puberty, not elsewhere classified
0.649 0.351 0.000
E26 Hyperaldosteronism
0.649 0.351 0.000
E25 Adrenogenital disorders
0.649 0.351 0.000
E20 Hypoparathyroidism
0.649 0.351 0.000
D12.4 Descending colon
0.648 0.351 0.000
H11 Other disorders of conjunctiva
0.648 0.352 0.000
H91 Other hearing loss
0.648 0.352 0.000
W20-W49 Exposure to inanimate mechanical forces
0.648 0.352 0.000
K92 Other diseases of digestive system
0.648 0.352 0.000
K11 Diseases of salivary glands
0.648 0.352 0.000
K63 Other diseases of intestine
0.647 0.353 0.000
N13.3 Other and unspecified hydronephrosis
0.647 0.353 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.647 0.353 0.000
Y59 Other and unspecified vaccines and biological substances
0.646 0.354 0.000
Y58 Bacterial vaccines
0.646 0.354 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.646 0.354 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.646 0.354 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.646 0.354 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.646 0.354 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.646 0.354 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.646 0.354 0.000
Y48 Anaesthetics and therapeutic gases
0.646 0.354 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.646 0.354 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.646 0.354 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.646 0.354 0.000
D25 Leiomyoma of uterus
0.646 0.354 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.646 0.354 0.000
D26 Other benign neoplasms of uterus
0.646 0.354 0.000
K50 Crohn's disease [regional enteritis]
0.646 0.354 0.000
Y84.6 Urinary catheterisation
0.646 0.354 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.645 0.355 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.645 0.355 0.000
I77.5 Necrosis of artery
0.644 0.356 0.000
I77.4 Coeliac artery compression syndrome
0.644 0.356 0.000
I77.3 Arterial fibromuscular dysplasia
0.644 0.356 0.000
I77.2 Rupture of artery
0.644 0.356 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.644 0.356 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.642 0.358 0.000
H74 Other disorders of middle ear and mastoid
0.642 0.358 0.000
H70 Mastoiditis and related conditions
0.642 0.358 0.000
H68 Eustachian salpingitis and obstruction
0.642 0.358 0.000
H67 Otitis media in diseases classified elsewhere
0.642 0.358 0.000
I30 Acute pericarditis
0.642 0.358 0.000
C76.0 Head, face and neck
0.642 0.358 0.000
K76.8 Other specified diseases of liver
0.642 0.358 0.000
Y86 Sequelae of other accidents
0.640 0.360 0.000
D48.1 Connective and other soft tissue
0.640 0.360 0.000
Y45.0 Opioids and related analgesics
0.640 0.360 0.000
F42 Obsessive-compulsive disorder
0.639 0.361 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.638 0.362 0.000
N02 Recurrent and persistent haematuria
0.638 0.362 0.000
K14 Diseases of tongue
0.636 0.364 0.000
D10 Benign neoplasm of mouth and pharynx
0.636 0.364 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.636 0.364 0.000
Y40.9 Systemic antibiotic, unspecified
0.635 0.365 0.000
K81.8 Other cholecystitis
0.634 0.366 0.000
S00-S09 Injuries to the head
0.634 0.366 0.000
I12.0 Hypertensive renal disease with renal failure
0.634 0.366 0.000
H49.0 Third [oculomotor] nerve palsy
0.633 0.367 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.633 0.367 0.000
K70.9 Alcoholic liver disease, unspecified
0.633 0.367 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.631 0.369 0.000
H43.3 Other vitreous opacities
0.630 0.369 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.630 0.369 0.000
C24.1 Ampulla of Vater
0.630 0.369 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.630 0.370 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.630 0.370 0.000
I46.9 Cardiac arrest, unspecified
0.630 0.370 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.629 0.371 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.629 0.371 0.000
E29 Testicular dysfunction
0.629 0.371 0.000
C18.5 Splenic flexure
0.628 0.372 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.627 0.372 0.000
Q61.3 Polycystic kidney, unspecified
0.627 0.373 0.000
K76.9 Liver disease, unspecified
0.626 0.373 0.000
D22 Melanocytic naevi
0.626 0.374 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.626 0.374 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.626 0.374 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.626 0.374 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.626 0.374 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.626 0.374 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.626 0.374 0.000
Y98 Lifestyle-related condition
0.626 0.374 0.000
Y97 Environmental-pollution-related condition
0.626 0.374 0.000
Y96 Work-related condition
0.626 0.374 0.000
H69.9 Eustachian tube disorder, unspecified
0.625 0.375 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.625 0.375 0.000
K42.1 Umbilical hernia with gangrene
0.625 0.375 0.000
H43.1 Vitreous haemorrhage
0.625 0.375 0.000
C18.9 Colon, unspecified
0.624 0.376 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.624 0.376 0.000
E10.3 With ophthalmic complications
0.624 0.376 0.000
C32 Malignant neoplasm of larynx
0.623 0.377 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.623 0.377 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.623 0.377 0.000
K83.0 Cholangitis
0.623 0.377 0.000
I27 Other pulmonary heart diseases
0.622 0.378 0.000
N18.0 End-stage renal disease
0.622 0.378 0.000
K74 Fibrosis and cirrhosis of liver
0.621 0.379 0.000
V10-V19 Pedal cyclist injured in transport accident
0.620 0.379 0.000
K10 Other diseases of jaws
0.620 0.379 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.619 0.381 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.619 0.381 0.000
I72.3 Aneurysm of iliac artery
0.618 0.382 0.000
N17 Acute renal failure
0.618 0.382 0.000
K61 Abscess of anal and rectal regions
0.617 0.383 0.000
Y89 Sequelae of other external causes
0.616 0.384 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.616 0.384 0.000
F10.3 Withdrawal state
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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