TreeWAS – Variant ID: rs12991146

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.513	0.487	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.491	0.509	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.485	0.515	0.000
O42 Premature rupture of membranes	0.463	0.537	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.461	0.539	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.458	0.542	0.000
O60-O75 Complications of labour and delivery	0.448	0.552	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.444	0.556	0.000
O47 False labour	0.439	0.561	0.000
O43 Placental disorders	0.433	0.567	0.000
O44 Placenta praevia	0.429	0.571	0.000
O40 Polyhydramnios	0.411	0.589	0.000
O42.9 Premature rupture of membranes, unspecified	0.410	0.590	0.000
O34.1 Maternal care for tumour of corpus uteri	0.401	0.599	0.000
O80-O84 Delivery	0.401	0.599	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.400	0.599	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.398	0.601	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.390	0.610	0.000
O30 Multiple gestation	0.390	0.610	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.389	0.611	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.388	0.612	0.000
O20 Haemorrhage in early pregnancy	0.384	0.616	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.383	0.617	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.382	0.618	0.000
O32.1 Maternal care for breech presentation	0.375	0.625	0.000
O43.8 Other placental disorders	0.369	0.631	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.369	0.631	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.369	0.631	0.000
O45 Premature separation of placenta [abruptio placentae]	0.368	0.632	0.000
O33 Maternal care for known or suspected disproportion	0.368	0.632	0.000
O31 Complications specific to multiple gestation	0.368	0.632	0.000
O62 Abnormalities of forces of labour	0.367	0.633	0.000
O85-O92 Complications predominantly related to the puerperium	0.366	0.634	0.000
O71 Other obstetric trauma	0.362	0.638	0.000
O44.1 Placenta praevia with haemorrhage	0.362	0.638	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.361	0.639	0.000
O41 Other disorders of amniotic fluid and membranes	0.357	0.643	0.000
O24 Diabetes mellitus in pregnancy	0.356	0.644	0.000
O23 Infections of genito-urinary tract in pregnancy	0.355	0.645	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.352	0.648	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.352	0.648	0.000
O34.6 Maternal care for abnormality of vagina	0.352	0.648	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.352	0.648	0.000
O34.4 Maternal care for other abnormalities of cervix	0.352	0.648	0.000
O34.3 Maternal care for cervical incompetence	0.352	0.648	0.000
O34.0 Maternal care for congenital malformation of uterus	0.352	0.648	0.000
O48 Prolonged pregnancy	0.349	0.651	0.000
O47.0 False labour before 37 completed weeks of gestation	0.343	0.657	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.341	0.659	0.000
O00-O08 Pregnancy with abortive outcome	0.339	0.661	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.339	0.661	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.338	0.662	0.000
O32.0 Maternal care for unstable lie	0.338	0.662	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.336	0.664	0.000
O20.0 Threatened abortion	0.334	0.666	0.000
O32.2 Maternal care for transverse and oblique lie	0.333	0.666	0.000
O32.8 Maternal care for other malpresentation of foetus	0.332	0.667	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.332	0.668	0.000
O72 Postpartum haemorrhage	0.330	0.670	0.000
O81 Single delivery by forceps and vacuum extractor	0.329	0.671	0.000
O32.6 Maternal care for compound presentation	0.329	0.671	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.329	0.671	0.000
O32.4 Maternal care for high head at term	0.329	0.671	0.000
O32.3 Maternal care for face, brow and chin presentation	0.329	0.671	0.000
O28 Abnormal findings on antenatal screening of mother	0.325	0.675	0.000
O80 Single spontaneous delivery	0.325	0.675	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.324	0.676	0.000
O43.1 Malformation of placenta	0.322	0.678	0.000
O74 Complications of anaesthesia during labour and delivery	0.322	0.678	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.322	0.678	0.000
O60 Preterm delivery	0.322	0.678	0.000
O61 Failed induction of labour	0.320	0.680	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.319	0.681	0.000
O29 Complications of anaesthesia during pregnancy	0.319	0.681	0.000
O22 Venous complications in pregnancy	0.319	0.681	0.000
O25 Malnutrition in pregnancy	0.319	0.681	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.318	0.682	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.318	0.682	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.317	0.683	0.000
O47.9 False labour, unspecified	0.316	0.684	0.000
O46.9 Antepartum haemorrhage, unspecified	0.316	0.684	0.000
O43.9 Placental disorder, unspecified	0.310	0.689	0.000
O43.2 Morbidly adherent placenta	0.310	0.689	0.000
O43.0 Placental transfusion syndromes	0.310	0.689	0.000
O62.2 Other uterine inertia	0.308	0.692	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.306	0.693	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.305	0.695	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.305	0.695	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.303	0.697	0.000
O04 Medical abortion	0.303	0.697	0.000
O30.0 Twin pregnancy	0.302	0.698	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.301	0.699	0.000
O73 Retained placenta and membranes, without haemorrhage	0.300	0.700	0.000
O71.4 Obstetric high vaginal laceration alone	0.300	0.700	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.298	0.702	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.298	0.702	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.297	0.703	0.000
O36 Maternal care for other known or suspected foetal problems	0.295	0.705	0.000
O26.8 Other specified pregnancy-related conditions	0.295	0.705	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.293	0.707	0.000
O21 Excessive vomiting in pregnancy	0.292	0.708	0.000
O84 Multiple delivery	0.287	0.713	0.000
O83 Other assisted single delivery	0.287	0.713	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.287	0.713	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.287	0.713	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.287	0.713	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.287	0.713	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.287	0.713	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.287	0.713	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.287	0.713	0.000
O86 Other puerperal infections	0.286	0.714	0.000
O46.8 Other antepartum haemorrhage	0.286	0.714	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.286	0.714	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.280	0.720	0.000
O30.9 Multiple gestation, unspecified	0.280	0.720	0.000
O30.8 Other multiple gestation	0.280	0.720	0.000
O30.2 Quadruplet pregnancy	0.280	0.720	0.000
O30.1 Triplet pregnancy	0.280	0.720	0.000
O81.4 Vacuum extractor delivery	0.278	0.722	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.277	0.723	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.277	0.723	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.275	0.725	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.275	0.725	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.275	0.725	0.000
O69.3 Labour and delivery complicated by short cord	0.275	0.725	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.275	0.725	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.275	0.725	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.274	0.726	0.000
O15 Eclampsia	0.274	0.726	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.274	0.726	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.274	0.726	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.273	0.727	0.000
O64.1 Obstructed labour due to breech presentation	0.273	0.727	0.000
O80.0 Spontaneous vertex delivery	0.273	0.727	0.000
O80.8 Other single spontaneous delivery	0.270	0.730	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.269	0.731	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.269	0.731	0.000
O72.1 Other immediate postpartum haemorrhage	0.268	0.732	0.000
O70 Perineal laceration during delivery	0.266	0.734	0.000
O20.8 Other haemorrhage in early pregnancy	0.265	0.735	0.000
O31.8 Other complications specific to multiple gestation	0.264	0.736	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.264	0.736	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.264	0.736	0.000
O31.0 Papyraceous foetus	0.264	0.736	0.000
O33.9 Maternal care for disproportion, unspecified	0.264	0.736	0.000
O33.8 Maternal care for disproportion of other origin	0.264	0.736	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.264	0.736	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.264	0.736	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.264	0.736	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.264	0.736	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.264	0.736	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.264	0.736	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.264	0.736	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.264	0.736	0.000
O45.9 Premature separation of placenta, unspecified	0.264	0.736	0.000
O45.8 Other premature separation of placenta	0.264	0.736	0.000
O45.0 Premature separation of placenta with coagulation defect	0.264	0.736	0.000
O69.8 Labour and delivery complicated by other cord complications	0.264	0.736	0.000
O62.9 Abnormality of forces of labour, unspecified	0.263	0.737	0.000
O62.8 Other abnormalities of forces of labour	0.263	0.737	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.263	0.737	0.000
O62.3 Precipitate labour	0.263	0.737	0.000
O62.1 Secondary uterine inertia	0.263	0.737	0.000
O62.0 Primary inadequate contractions	0.263	0.737	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.263	0.737	0.000
O91 Infections of breast associated with childbirth	0.263	0.737	0.000
O89 Complications of anaesthesia during the puerperium	0.263	0.737	0.000
O88 Obstetric embolism	0.263	0.737	0.000
O87 Venous complications in the puerperium	0.263	0.737	0.000
O85 Puerperal sepsis	0.263	0.737	0.000
O71.9 Obstetric trauma, unspecified	0.259	0.740	0.000
O71.8 Other specified obstetric trauma	0.259	0.740	0.000
O71.7 Obstetric haematoma of pelvis	0.259	0.740	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.259	0.740	0.000
O71.5 Other obstetric injury to pelvic organs	0.259	0.740	0.000
O71.3 Obstetric laceration of cervix	0.259	0.740	0.000
O71.2 Postpartum inversion of uterus	0.259	0.740	0.000
O71.1 Rupture of uterus during labour	0.259	0.740	0.000
O71.0 Rupture of uterus before onset of labour	0.259	0.740	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.259	0.741	0.000
O75.9 Complication of labour and delivery, unspecified	0.259	0.741	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.259	0.741	0.000
O75.4 Other complications of obstetric surgery and procedures	0.259	0.741	0.000
O75.3 Other infection during labour	0.259	0.741	0.000
O75.1 Shock during or following labour and delivery	0.259	0.741	0.000
O75.0 Maternal distress during labour and delivery	0.259	0.741	0.000
O82 Single delivery by Caesarean section	0.258	0.742	0.000
O04.4 Incomplete, without complication	0.258	0.742	0.000
O90 Complications of the puerperium, not elsewhere classified	0.256	0.743	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.256	0.743	0.000
O41.1 Infection of amniotic sac and membranes	0.256	0.743	0.000
O66 Other obstructed labour	0.255	0.744	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.255	0.745	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.255	0.745	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.255	0.745	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.255	0.745	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.255	0.745	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.254	0.745	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.254	0.745	0.000
O23.2 Infections of urethra in pregnancy	0.254	0.745	0.000
O23.1 Infections of bladder in pregnancy	0.254	0.745	0.000
O23.0 Infections of kidney in pregnancy	0.254	0.745	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.253	0.747	0.000
O63 Long labour	0.251	0.749	0.000
O23.5 Infections of the genital tract in pregnancy	0.250	0.750	0.000
O12.0 Gestational oedema	0.250	0.750	0.000
O72.0 Third-stage haemorrhage	0.245	0.755	0.000
O00 Ectopic pregnancy	0.244	0.756	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.243	0.756	0.000
O07 Failed attempted abortion	0.243	0.756	0.000
O06 Unspecified abortion	0.243	0.756	0.000
O05 Other abortion	0.243	0.756	0.000
O01 Hydatidiform mole	0.243	0.756	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.243	0.757	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.243	0.757	0.000
O26.5 Maternal hypotension syndrome	0.243	0.757	0.000
O26.4 Herpes gestationis	0.243	0.757	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.243	0.757	0.000
O26.2 Pregnancy care of habitual aborter	0.243	0.757	0.000
O26.1 Low weight gain in pregnancy	0.243	0.757	0.000
O26.0 Excessive weight gain in pregnancy	0.243	0.757	0.000
O04.9 Complete or unspecified, without complication	0.243	0.757	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.243	0.757	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.243	0.757	0.000
O64.5 Obstructed labour due to compound presentation	0.243	0.757	0.000
O64.4 Obstructed labour due to shoulder presentation	0.243	0.757	0.000
O64.3 Obstructed labour due to brow presentation	0.243	0.757	0.000
O64.2 Obstructed labour due to face presentation	0.243	0.757	0.000
O41.0 Oligohydramnios	0.242	0.757	0.000
O67.8 Other intrapartum haemorrhage	0.241	0.759	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.241	0.759	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.239	0.761	0.000
O72.3 Postpartum coagulation defects	0.237	0.763	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.236	0.764	0.000
O81.3 Other and unspecified forceps delivery	0.236	0.764	0.000
O81.2 Mid-cavity forceps with rotation	0.236	0.764	0.000
O81.1 Mid-cavity forceps delivery	0.236	0.764	0.000
O81.0 Low forceps delivery	0.236	0.764	0.000
O16 Unspecified maternal hypertension	0.234	0.766	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.233	0.767	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.233	0.767	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.233	0.767	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.233	0.767	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.233	0.767	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.233	0.767	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.233	0.767	0.000
O80.1 Spontaneous breech delivery	0.233	0.767	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.232	0.768	0.000
O60.3 Preterm delivery without spontaneous labour	0.231	0.769	0.000
O60.2 Preterm spontaneous labour with term delivery	0.231	0.769	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.231	0.769	0.000
O60.0 Preterm labour without delivery	0.231	0.769	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.231	0.769	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.231	0.769	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.231	0.769	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.231	0.769	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.231	0.769	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.231	0.769	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.231	0.769	0.000
O65.0 Obstructed labour due to deformed pelvis	0.231	0.769	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.231	0.769	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.231	0.769	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.231	0.769	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.231	0.769	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.231	0.769	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.231	0.769	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.231	0.769	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.231	0.769	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.231	0.769	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.231	0.769	0.000
O61.9 Failed induction of labour, unspecified	0.230	0.770	0.000
O61.8 Other failed induction of labour	0.230	0.770	0.000
O61.1 Failed instrumental induction of labour	0.230	0.770	0.000
O86.0 Infection of obstetric surgical wound	0.229	0.771	0.000
O22.9 Venous complication in pregnancy, unspecified	0.229	0.771	0.000
O22.8 Other venous complications in pregnancy	0.229	0.771	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.229	0.771	0.000
O22.4 Haemorrhoids in pregnancy	0.229	0.771	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.229	0.771	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.229	0.771	0.000
O22.1 Genital varices in pregnancy	0.229	0.771	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.229	0.771	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.229	0.771	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.229	0.771	0.000
O29.6 Failed or difficult intubation during pregnancy	0.229	0.771	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.229	0.771	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.229	0.771	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.229	0.771	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.229	0.771	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.229	0.771	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.229	0.771	0.000
O61.0 Failed medical induction of labour	0.228	0.771	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.227	0.773	0.000
O97 Death from sequelae of direct obstetric causes	0.227	0.773	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.227	0.773	0.000
O95 Obstetric death of unspecified cause	0.227	0.773	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.227	0.773	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.224	0.776	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.223	0.777	0.000
O12.2 Gestational oedema with proteinuria	0.219	0.781	0.000
O12.1 Gestational proteinuria	0.219	0.781	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.217	0.783	0.000
O04.7 Complete or unspecified, complicated by embolism	0.217	0.783	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.217	0.783	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.217	0.783	0.000
O04.3 Incomplete, with other and unspecified complications	0.217	0.783	0.000
O04.2 Incomplete, complicated by embolism	0.217	0.783	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.217	0.783	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.215	0.784	0.000
O36.9 Maternal care for foetal problem, unspecified	0.215	0.785	0.000
O70.0 First degree perineal laceration during delivery	0.214	0.786	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.211	0.788	0.000
O36.4 Maternal care for intra-uterine death	0.211	0.788	0.000
O36.2 Maternal care for hydrops foetalis	0.211	0.788	0.000
O36.1 Maternal care for other isoimmunisation	0.211	0.788	0.000
O21.9 Vomiting of pregnancy, unspecified	0.209	0.791	0.000
O21.8 Other vomiting complicating pregnancy	0.209	0.791	0.000
O21.2 Late vomiting of pregnancy	0.209	0.791	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.209	0.791	0.000
O36.6 Maternal care for excessive foetal growth	0.208	0.792	0.000
O83.9 Assisted single delivery, unspecified	0.206	0.794	0.000
O83.8 Other specified assisted single delivery	0.206	0.794	0.000
O83.4 Destructive operation for delivery	0.206	0.794	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.206	0.794	0.000
O83.2 Other manipulation-assisted delivery	0.206	0.794	0.000
O83.1 Other assisted breech delivery	0.206	0.794	0.000
O83.0 Breech extraction	0.206	0.794	0.000
O84.9 Multiple delivery, unspecified	0.206	0.794	0.000
O84.8 Other multiple delivery	0.206	0.794	0.000
O84.2 Multiple delivery, all by Caesarean section	0.206	0.794	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.206	0.794	0.000
O84.0 Multiple delivery, all spontaneous	0.206	0.794	0.000
O75.8 Other specified complications of labour and delivery	0.206	0.794	0.000
O86.8 Other specified puerperal infections	0.205	0.794	0.000
O86.4 Pyrexia of unknown origin following delivery	0.205	0.794	0.000
O86.3 Other genito-urinary tract infections following delivery	0.205	0.794	0.000
O86.2 Urinary tract infection following delivery	0.205	0.794	0.000
O86.1 Other infection of genital tract following delivery	0.205	0.794	0.000
O14.0 Moderate preeclampsia	0.205	0.795	0.000
O63.9 Long labour, unspecified	0.204	0.796	0.000
O36.5 Maternal care for poor foetal growth	0.200	0.800	0.000
O14.2 HELLP syndrome	0.199	0.801	0.000
O14.1 Severe preeclampsia	0.199	0.801	0.000
O70.9 Perineal laceration during delivery, unspecified	0.197	0.803	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.196	0.803	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.196	0.803	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.196	0.803	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.196	0.803	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.196	0.803	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.196	0.803	0.000
O15.9 Eclampsia, unspecified as to time period	0.196	0.803	0.000
O15.2 Eclampsia in the puerperium	0.196	0.803	0.000
O15.1 Eclampsia in labour	0.196	0.803	0.000
O15.0 Eclampsia in pregnancy	0.196	0.803	0.000
O14.9 Preeclampsia, unspecified	0.196	0.804	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.196	0.804	0.000
O73.0 Retained placenta, without haemorrhage	0.194	0.806	0.000
O03 Spontaneous abortion	0.194	0.806	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.193	0.807	0.000
O36.8 Maternal care for other specified foetal problems	0.192	0.808	0.000
O70.3 Fourth degree perineal laceration during delivery	0.191	0.809	0.000
O87.9 Venous complication in the puerperium, unspecified	0.188	0.811	0.000
O87.8 Other venous complications in the puerperium	0.188	0.811	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.188	0.811	0.000
O87.2 Haemorrhoids in the puerperium	0.188	0.811	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.188	0.811	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.188	0.811	0.000
O88.8 Other obstetric embolism	0.188	0.811	0.000
O88.3 Obstetric pyaemic and septic embolism	0.188	0.811	0.000
O88.2 Obstetric blood-clot embolism	0.188	0.811	0.000
O88.1 Amniotic fluid embolism	0.188	0.811	0.000
O88.0 Obstetric air embolism	0.188	0.811	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.188	0.811	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.188	0.811	0.000
O89.6 Failed or difficult intubation during the puerperium	0.188	0.811	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.188	0.811	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.188	0.811	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.188	0.811	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.188	0.811	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.188	0.811	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.188	0.811	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.188	0.811	0.000
O91.1 Abscess of breast associated with childbirth	0.188	0.811	0.000
O91.0 Infection of nipple associated with childbirth	0.188	0.811	0.000
O92.7 Other and unspecified disorders of lactation	0.188	0.811	0.000
O92.6 Galactorrhoea	0.188	0.811	0.000
O92.5 Suppressed lactation	0.188	0.811	0.000
O92.4 Hypogalactia	0.188	0.811	0.000
O92.3 Agalactia	0.188	0.811	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.188	0.811	0.000
O92.1 Cracked nipple associated with childbirth	0.188	0.811	0.000
O92.0 Retracted nipple associated with childbirth	0.188	0.811	0.000
O82.9 Delivery by Caesarean section, unspecified	0.185	0.815	0.000
O82.8 Other single delivery by Caesarean section	0.185	0.815	0.000
O82.2 Delivery by Caesarean hysterectomy	0.185	0.815	0.000
O90.9 Complication of the puerperium, unspecified	0.184	0.816	0.000
O90.5 Postpartum thyroiditis	0.184	0.816	0.000
O90.4 Postpartum acute renal failure	0.184	0.816	0.000
O90.3 Cardiomyopathy in the puerperium	0.184	0.816	0.000
O90.2 Haematoma of obstetric wound	0.184	0.816	0.000
O90.1 Disruption of perineal obstetric wound	0.184	0.816	0.000
O90.0 Disruption of Caesarean section wound	0.184	0.816	0.000
O66.9 Obstructed labour, unspecified	0.183	0.816	0.000
O66.8 Other specified obstructed labour	0.183	0.816	0.000
O66.4 Failed trial of labour, unspecified	0.183	0.816	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.183	0.816	0.000
O66.2 Obstructed labour due to unusually large foetus	0.183	0.816	0.000
O66.1 Obstructed labour due to locked twins	0.183	0.816	0.000
O82.1 Delivery by emergency Caesarean section	0.183	0.817	0.000
O21.0 Mild hyperemesis gravidarum	0.182	0.817	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.180	0.820	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.177	0.822	0.000
O26.9 Pregnancy-related condition, unspecified	0.177	0.823	0.000
O00.1 Tubal pregnancy	0.176	0.824	0.000
O00.9 Ectopic pregnancy, unspecified	0.175	0.825	0.000
O00.8 Other ectopic pregnancy	0.175	0.825	0.000
O00.2 Ovarian pregnancy	0.175	0.825	0.000
O00.0 Abdominal pregnancy	0.175	0.825	0.000
O01.9 Hydatidiform mole, unspecified	0.175	0.825	0.000
O01.1 Incomplete and partial hydatidiform mole	0.175	0.825	0.000
O01.0 Classical hydatidiform mole	0.175	0.825	0.000
O05.9 Complete or unspecified, without complication	0.175	0.825	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.175	0.825	0.000
O05.7 Complete or unspecified, complicated by embolism	0.175	0.825	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.175	0.825	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.175	0.825	0.000
O05.4 Incomplete, without complication	0.175	0.825	0.000
O05.3 Incomplete, with other and unspecified complications	0.175	0.825	0.000
O05.2 Incomplete, complicated by embolism	0.175	0.825	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.175	0.825	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.175	0.825	0.000
O06.9 Complete or unspecified, without complication	0.175	0.825	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.175	0.825	0.000
O06.7 Complete or unspecified, complicated by embolism	0.175	0.825	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.175	0.825	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.175	0.825	0.000
O06.4 Incomplete, without complication	0.175	0.825	0.000
O06.3 Incomplete, with other and unspecified complications	0.175	0.825	0.000
O06.2 Incomplete, complicated by embolism	0.175	0.825	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.175	0.825	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.175	0.825	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.175	0.825	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.175	0.825	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.175	0.825	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.175	0.825	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.175	0.825	0.000
O07.4 Failed medical abortion, without complication	0.175	0.825	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.175	0.825	0.000
O07.2 Failed medical abortion, complicated by embolism	0.175	0.825	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.175	0.825	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.175	0.825	0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.175	0.825	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.175	0.825	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.175	0.825	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.175	0.825	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.175	0.825	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.175	0.825	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.175	0.825	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.175	0.825	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.175	0.825	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.175	0.825	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.172	0.828	0.000
O80.9 Single spontaneous delivery, unspecified	0.165	0.835	0.000
O70.2 Third degree perineal laceration during delivery	0.165	0.835	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.163	0.837	0.000
O96.9 Death from unspecified obstetric cause	0.163	0.837	0.000
O96.1 Death from indirect obstetric cause	0.163	0.837	0.000
O96.0 Death from direct obstetric cause	0.163	0.837	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.163	0.837	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.163	0.837	0.000
O97.0 Death from sequelae of direct obstetric cause	0.163	0.837	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.163	0.837	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.163	0.837	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.163	0.837	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.163	0.837	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.163	0.837	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.163	0.837	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.163	0.837	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.163	0.837	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.163	0.837	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.163	0.837	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.162	0.838	0.000
O82.0 Delivery by elective Caesarean section	0.159	0.841	0.000
O02 Other abnormal products of conception	0.158	0.842	0.000
O63.1 Prolonged second stage (of labour)	0.153	0.847	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.149	0.851	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.140	0.859	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.140	0.859	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.140	0.859	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.140	0.859	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.139	0.861	0.000
O03.7 Complete or unspecified, complicated by embolism	0.139	0.861	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.139	0.861	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.139	0.861	0.000
O03.3 Incomplete, with other and unspecified complications	0.139	0.861	0.000
O03.2 Incomplete, complicated by embolism	0.139	0.861	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.139	0.861	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.139	0.861	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.136	0.863	0.001
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.136	0.863	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations