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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13132569
log Bayes Factor = 2.55457
Chromosome 4   position 61,603,156  (GRCh37) Explore rs13132569 on Ensembl!
Variant rs13132569 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.997 0.003 0.000
Chapter II Neoplasms
0.994 0.006 0.000
D10-D36 Benign neoplasms
0.990 0.010 0.000
Chapter XIV Diseases of the genitourinary system
0.971 0.029 0.000
D27 Benign neoplasm of ovary
0.950 0.050 0.000
Chapter V Mental and behavioural disorders
0.950 0.050 0.000
N30-N39 Other diseases of urinary system
0.946 0.054 0.000
Chapter XI Diseases of the digestive system
0.940 0.060 0.000
Chapter VII Diseases of the eye and adnexa
0.927 0.073 0.000
D25 Leiomyoma of uterus
0.921 0.079 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.900 0.100 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.880 0.120 0.000
N32 Other disorders of bladder
0.871 0.129 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.866 0.134 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.863 0.137 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.849 0.151 0.000
D00-D09 In situ neoplasms
0.838 0.162 0.000
N30 Cystitis
0.835 0.165 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.830 0.170 0.000
D17 Benign lipomatous neoplasm
0.830 0.170 0.000
N32.8 Other specified disorders of bladder
0.822 0.178 0.000
C50-C50 Malignant neoplasm of breast
0.821 0.179 0.000
D25.9 Leiomyoma of uterus, unspecified
0.819 0.181 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.819 0.181 0.000
H30-H36 Disorders of choroid and retina
0.807 0.193 0.000
K55-K64 Other diseases of intestines
0.806 0.194 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.800 0.200 0.000
K50-K52 Noninfective enteritis and colitis
0.793 0.207 0.000
K70-K77 Diseases of liver
0.792 0.208 0.000
Chapter IX Diseases of the circulatory system
0.789 0.210 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.788 0.212 0.000
D25.1 Intramural leiomyoma of uterus
0.787 0.213 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.782 0.218 0.000
F30-F39 Mood [affective] disorders
0.778 0.221 0.000
D18 Haemangioma and lymphangioma, any site
0.774 0.226 0.000
K90-K93 Other diseases of the digestive system
0.773 0.227 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.773 0.227 0.000
N39 Other disorders of urinary system
0.767 0.233 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.764 0.236 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.763 0.237 0.000
K62 Other diseases of anus and rectum
0.759 0.241 0.000
I10-I15 Hypertensive diseases
0.758 0.242 0.000
H53-H54 Visual disturbances and blindness
0.757 0.243 0.000
M05-M14 Inflammatory polyarthropathies
0.756 0.244 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.754 0.246 0.000
D24 Benign neoplasm of breast
0.754 0.246 0.000
N25-N29 Other disorders of kidney and ureter
0.751 0.248 0.000
N81 Female genital prolapse
0.751 0.249 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.749 0.251 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.746 0.253 0.000
N35 Urethral stricture
0.745 0.255 0.000
N80 Endometriosis
0.744 0.256 0.000
C51-C58 Malignant neoplasms of female genital organs
0.739 0.261 0.000
H25-H28 Disorders of lens
0.736 0.264 0.000
M45-M49 Spondylopathies
0.734 0.266 0.000
I10 Essential (primary) hypertension
0.727 0.273 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.727 0.273 0.000
Chapter VIII Diseases of the ear and mastoid process
0.725 0.275 0.000
N10-N16 Renal tubulo-interstitial diseases
0.725 0.275 0.000
M80-M85 Disorders of bone density and structure
0.724 0.275 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.724 0.276 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.722 0.278 0.000
D22 Melanocytic naevi
0.720 0.280 0.000
N30.8 Other cystitis
0.718 0.282 0.000
D05 Carcinoma in situ of breast
0.717 0.283 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.716 0.283 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.716 0.284 0.000
Chapter XXII Codes for special purposes
0.715 0.285 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.715 0.285 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.713 0.287 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.713 0.287 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.713 0.287 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.713 0.287 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.713 0.287 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.712 0.288 0.000
S60-S69 Injuries to the wrist and hand
0.712 0.288 0.000
D36 Benign neoplasm of other and unspecified sites
0.710 0.290 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.710 0.290 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.710 0.290 0.000
D32 Benign neoplasm of meninges
0.710 0.290 0.000
D31 Benign neoplasm of eye and adnexa
0.710 0.290 0.000
D30 Benign neoplasm of urinary organs
0.710 0.290 0.000
D29 Benign neoplasm of male genital organs
0.710 0.290 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.710 0.290 0.000
D26 Other benign neoplasms of uterus
0.710 0.290 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.710 0.290 0.000
D19 Benign neoplasm of mesothelial tissue
0.710 0.290 0.000
D16 Benign neoplasm of bone and articular cartilage
0.710 0.290 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.710 0.290 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.710 0.290 0.000
D11 Benign neoplasm of major salivary glands
0.710 0.290 0.000
D10 Benign neoplasm of mouth and pharynx
0.710 0.290 0.000
D34 Benign neoplasm of thyroid gland
0.710 0.290 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.707 0.293 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.707 0.293 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.701 0.299 0.000
N60-N64 Disorders of breast
0.699 0.301 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.698 0.302 0.000
D23 Other benign neoplasms of skin
0.697 0.303 0.000
N99-N99 Other disorders of the genitourinary system
0.696 0.303 0.000
C50 Malignant neoplasm of breast
0.696 0.304 0.000
K51 Ulcerative colitis
0.696 0.304 0.000
Chapter XX External causes of morbidity and mortality
0.693 0.307 0.000
F41 Other anxiety disorders
0.693 0.307 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.693 0.307 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.691 0.309 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.686 0.314 0.000
D50-D53 Nutritional anaemias
0.685 0.315 0.000
Chapter I Certain infectious and parasitic diseases
0.685 0.315 0.000
M15-M19 Arthrosis
0.684 0.316 0.000
H43-H45 Disorders of vitreous body and globe
0.683 0.317 0.000
H40-H42 Glaucoma
0.682 0.318 0.000
K65-K67 Diseases of peritoneum
0.681 0.319 0.000
F99-F99 Unspecified mental disorder
0.681 0.319 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.681 0.319 0.000
F80-F89 Disorders of psychological development
0.681 0.319 0.000
F70-F79 Mental retardation
0.681 0.319 0.000
F60-F69 Disorders of adult personality and behaviour
0.681 0.319 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.681 0.319 0.000
Chapter VI Diseases of the nervous system
0.679 0.321 0.000
N37 Urethral disorders in diseases classified elsewhere
0.678 0.321 0.000
N36 Other disorders of urethra
0.678 0.321 0.000
N34 Urethritis and urethral syndrome
0.678 0.321 0.000
N33 Bladder disorders in diseases classified elsewhere
0.678 0.321 0.000
C60-C63 Malignant neoplasms of male genital organs
0.677 0.323 0.000
D25.2 Subserosal leiomyoma of uterus
0.675 0.324 0.000
C64-C68 Malignant neoplasms of urinary tract
0.673 0.327 0.000
D80-D89 Certain disorders involving the immune mechanism
0.671 0.329 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.671 0.329 0.000
S50-S59 Injuries to the elbow and forearm
0.670 0.330 0.000
K62.1 Rectal polyp
0.670 0.330 0.000
N17-N19 Renal failure
0.669 0.331 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.668 0.332 0.000
N30.3 Trigonitis
0.665 0.335 0.000
O00-O08 Pregnancy with abortive outcome
0.665 0.335 0.000
H55-H59 Other disorders of eye and adnexa
0.665 0.335 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.665 0.335 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.665 0.335 0.000
H10-H13 Disorders of conjunctiva
0.665 0.335 0.000
F32 Depressive episode
0.664 0.336 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.663 0.337 0.000
D25.0 Submucous leiomyoma of uterus
0.662 0.338 0.000
S20-S29 Injuries to the thorax
0.661 0.339 0.000
M20-M25 Other joint disorders
0.659 0.341 0.000
L82 Seborrhoeic keratosis
0.654 0.346 0.000
N00-N08 Glomerular diseases
0.653 0.347 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.652 0.348 0.000
N97 Female infertility
0.651 0.349 0.000
H33 Retinal detachments and breaks
0.650 0.350 0.000
K62.8 Other specified diseases of anus and rectum
0.650 0.350 0.000
M65-M68 Disorders of synovium and tendon
0.648 0.352 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.646 0.354 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.645 0.354 0.000
M91-M94 Chondropathies
0.645 0.354 0.000
M86-M90 Other osteopathies
0.645 0.354 0.000
M60-M63 Disorders of muscles
0.645 0.354 0.000
M00-M03 Infectious arthropathies
0.645 0.354 0.000
N87 Dysplasia of cervix uteri
0.643 0.357 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.640 0.360 0.000
K61 Abscess of anal and rectal regions
0.638 0.362 0.000
F17.1 Harmful use
0.638 0.362 0.000
H53 Visual disturbances
0.635 0.365 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.633 0.367 0.000
K81 Cholecystitis
0.633 0.367 0.000
N32.0 Bladder-neck obstruction
0.632 0.368 0.000
M40-M43 Deforming dorsopathies
0.631 0.369 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.631 0.369 0.000
K35-K38 Diseases of appendix
0.631 0.369 0.000
N98 Complications associated with artificial fertilisation
0.631 0.369 0.000
N91 Absent, scanty and rare menstruation
0.631 0.369 0.000
N82 Fistulae involving female genital tract
0.631 0.369 0.000
N96 Habitual aborter
0.631 0.369 0.000
C15-C26 Malignant neoplasms of digestive organs
0.630 0.369 0.000
K76 Other diseases of liver
0.630 0.369 0.000
C34 Malignant neoplasm of bronchus and lung
0.629 0.371 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.628 0.371 0.000
N83.2 Other and unspecified ovarian cysts
0.627 0.373 0.000
M06 Other rheumatoid arthritis
0.627 0.373 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.627 0.373 0.000
N80.0 Endometriosis of uterus
0.625 0.375 0.000
N32.4 Rupture of bladder, nontraumatic
0.624 0.376 0.000
N32.2 Vesical fistula, not elsewhere classified
0.624 0.376 0.000
N32.1 Vesicointestinal fistula
0.624 0.376 0.000
N81.6 Rectocele
0.623 0.377 0.000
H36 Retinal disorders in diseases classified elsewhere
0.623 0.377 0.000
E10-E14 Diabetes mellitus
0.622 0.378 0.000
T79-T79 Certain early complications of trauma
0.621 0.379 0.000
T33-T35 Frostbite
0.621 0.379 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.621 0.379 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.621 0.379 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.621 0.379 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.621 0.379 0.000
T00-T07 Injuries involving multiple body regions
0.621 0.379 0.000
S90-S99 Injuries to the ankle and foot
0.621 0.379 0.000
S10-S19 Injuries to the neck
0.621 0.379 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.621 0.379 0.000
C50.9 Breast, unspecified
0.621 0.379 0.000
N84 Polyp of female genital tract
0.620 0.380 0.000
E00-E07 Disorders of thyroid gland
0.620 0.380 0.000
H34 Retinal vascular occlusions
0.620 0.380 0.000
K80 Cholelithiasis
0.620 0.380 0.000
D18.0 Haemangioma, any site
0.619 0.381 0.000
D55-D59 Haemolytic anaemias
0.619 0.381 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.618 0.382 0.000
N20-N23 Urolithiasis
0.618 0.382 0.000
H35 Other retinal disorders
0.618 0.382 0.000
K70 Alcoholic liver disease
0.618 0.382 0.000
S40-S49 Injuries to the shoulder and upper arm
0.617 0.383 0.000
N32.3 Diverticulum of bladder
0.617 0.383 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.616 0.384 0.000
D06 Carcinoma in situ of cervix uteri
0.616 0.384 0.000
H26 Other cataract
0.616 0.384 0.000
D60-D64 Aplastic and other anaemias
0.616 0.384 0.000
T66-T78 Other and unspecified effects of external causes
0.615 0.385 0.000
M50-M54 Other dorsopathies
0.615 0.385 0.000
K90 Intestinal malabsorption
0.615 0.385 0.000
S80-S89 Injuries to the knee and lower leg
0.615 0.385 0.000
S70-S79 Injuries to the hip and thigh
0.613 0.387 0.000
K60 Fissure and fistula of anal and rectal regions
0.612 0.388 0.000
M70-M79 Other soft tissue disorders
0.611 0.389 0.000
N30.9 Cystitis, unspecified
0.610 0.390 0.000
I60-I69 Cerebrovascular diseases
0.610 0.390 0.000
D12.6 Colon, unspecified
0.610 0.390 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.609 0.391 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.609 0.391 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.609 0.391 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.609 0.391 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.609 0.391 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.609 0.391 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.609 0.391 0.000
F11 Mental and behavioural disorders due to use of opioids
0.609 0.391 0.000
K62.0 Anal polyp
0.609 0.391 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.608 0.391 0.000
S00-S09 Injuries to the head
0.608 0.392 0.000
N39.0 Urinary tract infection, site not specified
0.608 0.392 0.000
E20-E35 Disorders of other endocrine glands
0.608 0.392 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.605 0.394 0.000
L40-L45 Papulosquamous disorders
0.605 0.395 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.603 0.396 0.000
K51.9 Ulcerative colitis, unspecified
0.603 0.397 0.000
K74 Fibrosis and cirrhosis of liver
0.603 0.397 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.602 0.397 0.000
L50-L54 Urticaria and erythema
0.602 0.397 0.000
N89 Other noninflammatory disorders of vagina
0.602 0.398 0.000
N35.9 Urethral stricture, unspecified
0.601 0.399 0.000
D09 Carcinoma in situ of other and unspecified sites
0.601 0.399 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.601 0.399 0.000
D04 Carcinoma in situ of skin
0.601 0.399 0.000
D03 Melanoma in situ
0.601 0.399 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.601 0.399 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.601 0.399 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.601 0.399 0.000
N30.4 Irradiation cystitis
0.599 0.401 0.000
N30.2 Other chronic cystitis
0.599 0.401 0.000
N30.1 Interstitial cystitis (chronic)
0.599 0.401 0.000
N30.0 Acute cystitis
0.599 0.401 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.598 0.402 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.597 0.403 0.000
I12 Hypertensive renal disease
0.596 0.404 0.000
O85-O92 Complications predominantly related to the puerperium
0.595 0.405 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.595 0.405 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.595 0.405 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.595 0.405 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.595 0.405 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.595 0.405 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.595 0.405 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.594 0.406 0.000
O80-O84 Delivery
0.594 0.406 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.594 0.406 0.000
N32.9 Bladder disorder, unspecified
0.593 0.407 0.000
M10 Gout
0.593 0.407 0.000
D12.8 Rectum
0.593 0.407 0.000
F41.9 Anxiety disorder, unspecified
0.593 0.407 0.000
K92 Other diseases of digestive system
0.591 0.409 0.000
N39.3 Stress incontinence
0.590 0.410 0.000
E70-E90 Metabolic disorders
0.589 0.411 0.000
N81.4 Uterovaginal prolapse, unspecified
0.588 0.412 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.588 0.412 0.000
L10-L14 Bullous disorders
0.587 0.413 0.000
M47 Spondylosis
0.587 0.413 0.000
N81.8 Other female genital prolapse
0.584 0.416 0.000
K13 Other diseases of lip and oral mucosa
0.584 0.416 0.000
F32.9 Depressive episode, unspecified
0.582 0.418 0.000
N88 Other noninflammatory disorders of cervix uteri
0.582 0.418 0.000
N80.1 Endometriosis of ovary
0.582 0.418 0.000
K55 Vascular disorders of intestine
0.581 0.418 0.000
M23 Internal derangement of knee
0.581 0.418 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.579 0.421 0.000
H31 Other disorders of choroid
0.579 0.421 0.000
H30 Chorioretinal inflammation
0.579 0.421 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.578 0.422 0.000
K04 Diseases of pulp and periapical tissues
0.578 0.422 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.577 0.422 0.000
C56 Malignant neoplasm of ovary
0.577 0.423 0.000
N92 Excessive, frequent and irregular menstruation
0.576 0.424 0.000
N93 Other abnormal uterine and vaginal bleeding
0.575 0.424 0.000
D05.1 Intraductal carcinoma in situ
0.575 0.425 0.000
F48 Other neurotic disorders
0.574 0.426 0.000
F45 Somatoform disorders
0.574 0.426 0.000
F44 Dissociative [conversion] disorders
0.574 0.426 0.000
F43 Reaction to severe stress, and adjustment disorders
0.574 0.426 0.000
F42 Obsessive-compulsive disorder
0.574 0.426 0.000
F40 Phobic anxiety disorders
0.574 0.426 0.000
N39.8 Other specified disorders of urinary system
0.573 0.426 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.573 0.427 0.000
L91 Hypertrophic disorders of skin
0.573 0.427 0.000
D75 Other diseases of blood and blood-forming organs
0.571 0.428 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.571 0.429 0.000
M81 Osteoporosis without pathological fracture
0.570 0.430 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.570 0.430 0.000
F10.1 Harmful use
0.569 0.431 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.568 0.432 0.000
K77 Liver disorders in diseases classified elsewhere
0.568 0.432 0.000
K75 Other inflammatory liver diseases
0.568 0.432 0.000
K73 Chronic hepatitis, not elsewhere classified
0.568 0.432 0.000
K72 Hepatic failure, not elsewhere classified
0.568 0.432 0.000
K71 Toxic liver disease
0.568 0.432 0.000
D70 Agranulocytosis
0.568 0.432 0.000
K08 Other disorders of teeth and supporting structures
0.567 0.433 0.000
N81.5 Vaginal enterocele
0.566 0.433 0.000
C79 Secondary malignant neoplasm of other sites
0.566 0.433 0.000
L20-L30 Dermatitis and eczema
0.566 0.434 0.000
I00-I02 Acute rheumatic fever
0.566 0.434 0.000
S61 Open wound of wrist and hand
0.565 0.434 0.000
E40-E46 Malnutrition
0.565 0.435 0.000
K62.4 Stenosis of anus and rectum
0.564 0.436 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.564 0.436 0.000
N39.9 Disorder of urinary system, unspecified
0.563 0.436 0.000
K52 Other non-infective gastro-enteritis and colitis
0.562 0.438 0.000
N86 Erosion and ectropion of cervix uteri
0.561 0.438 0.000
M46 Other inflammatory spondylopathies
0.561 0.439 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.560 0.439 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.560 0.439 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.560 0.439 0.000
C32 Malignant neoplasm of larynx
0.560 0.439 0.000
C31 Malignant neoplasm of accessory sinuses
0.560 0.439 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.560 0.439 0.000
C37 Malignant neoplasm of thymus
0.560 0.439 0.000
C33 Malignant neoplasm of trachea
0.560 0.439 0.000
K50 Crohn's disease [regional enteritis]
0.559 0.440 0.000
F38 Other mood [affective] disorders
0.558 0.442 0.000
F34 Persistent mood [affective] disorders
0.558 0.442 0.000
F33 Recurrent depressive disorder
0.558 0.442 0.000
F30 Manic episode
0.558 0.442 0.000
F39 Unspecified mood [affective] disorder
0.558 0.442 0.000
D50 Iron deficiency anaemia
0.558 0.442 0.000
M85 Other disorders of bone density and structure
0.557 0.443 0.000
K51.8 Other ulcerative colitis
0.557 0.443 0.000
N40-N51 Diseases of male genital organs
0.557 0.443 0.000
N83.1 Corpus luteum cyst
0.556 0.444 0.000
D18.1 Lymphangioma, any site
0.555 0.445 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.554 0.446 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.554 0.446 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.554 0.446 0.000
N83.7 Haematoma of broad ligament
0.554 0.446 0.000
N83.6 Haematosalpinx
0.554 0.446 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.554 0.446 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.554 0.446 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.554 0.446 0.000
M45 Ankylosing spondylitis
0.554 0.446 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.553 0.447 0.000
N81.1 Cystocele
0.552 0.448 0.000
K62.6 Ulcer of anus and rectum
0.551 0.449 0.000
D72 Other disorders of white blood cells
0.550 0.450 0.000
N39.2 Orthostatic proteinuria, unspecified
0.550 0.450 0.000
N39.1 Persistent proteinuria, unspecified
0.550 0.450 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.549 0.451 0.000
L81 Other disorders of pigmentation
0.548 0.451 0.000
L90 Atrophic disorders of skin
0.548 0.452 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.548 0.452 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.548 0.452 0.000
L94 Other localised connective tissue disorders
0.548 0.452 0.000
L93 Lupus erythematosus
0.548 0.452 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.548 0.452 0.000
L89 Decubitus ulcer
0.548 0.452 0.000
L87 Transepidermal elimination disorders
0.548 0.452 0.000
L85 Other epidermal thickening
0.548 0.452 0.000
L88 Pyoderma gangrenosum
0.548 0.452 0.000
L86 Keratoderma in diseases classified elsewhere
0.548 0.452 0.000
L84 Corns and callosities
0.548 0.452 0.000
L83 Acanthosis nigricans
0.548 0.452 0.000
L80 Vitiligo
0.548 0.452 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.547 0.453 0.000
K86 Other diseases of pancreas
0.547 0.453 0.000
K85 Acute pancreatitis
0.547 0.453 0.000
K81.1 Chronic cholecystitis
0.547 0.453 0.000
D12.7 Rectosigmoid junction
0.547 0.453 0.000
B95-B98 Bacterial, viral and other infectious agents
0.546 0.454 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.546 0.454 0.000
E50-E64 Other nutritional deficiencies
0.546 0.454 0.000
N85.2 Hypertrophy of uterus
0.544 0.456 0.000
K14 Diseases of tongue
0.544 0.456 0.000
K62.9 Disease of anus and rectum, unspecified
0.544 0.456 0.000
K62.7 Radiation proctitis
0.544 0.456 0.000
K62.2 Anal prolapse
0.544 0.456 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.544 0.456 0.000
K59 Other functional intestinal disorders
0.544 0.456 0.000
H80-H83 Diseases of inner ear
0.544 0.456 0.000
I15 Secondary hypertension
0.543 0.457 0.000
I13 Hypertensive heart and renal disease
0.543 0.457 0.000
I11 Hypertensive heart disease
0.543 0.457 0.000
M16 Coxarthrosis [arthrosis of hip]
0.543 0.457 0.000
K62.5 Haemorrhage of anus and rectum
0.543 0.457 0.000
H54 Blindness and low vision
0.542 0.457 0.000
M14 Arthropathies in other diseases classified elsewhere
0.542 0.458 0.000
M12 Other specific arthropathies
0.542 0.458 0.000
M11 Other crystal arthropathies
0.542 0.458 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.542 0.458 0.000
M08 Juvenile arthritis
0.542 0.458 0.000
M07 Psoriatic and enteropathic arthropathies
0.542 0.458 0.000
M05 Seropositive rheumatoid arthritis
0.542 0.458 0.000
F31 Bipolar affective disorder
0.542 0.458 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.541 0.459 0.000
I05-I09 Chronic rheumatic heart diseases
0.541 0.459 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.541 0.459 0.000
K12 Stomatitis and related lesions
0.541 0.459 0.000
K11 Diseases of salivary glands
0.541 0.459 0.000
K10 Other diseases of jaws
0.541 0.459 0.000
K09 Cysts of oral region, not elsewhere classified
0.541 0.459 0.000
K07 Dentofacial anomalies [including malocclusion]
0.541 0.459 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.541 0.459 0.000
K05 Gingivitis and periodontal diseases
0.541 0.459 0.000
K03 Other diseases of hard tissues of teeth
0.541 0.459 0.000
K00 Disorders of tooth development and eruption
0.541 0.459 0.000
N63 Unspecified lump in breast
0.539 0.461 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.539 0.461 0.000
N27 Small kidney of unknown cause
0.539 0.461 0.000
N25 Disorders resulting from impaired renal tubular function
0.539 0.461 0.000
N26 Unspecified contracted kidney
0.539 0.461 0.000
N81.9 Female genital prolapse, unspecified
0.538 0.461 0.000
N81.3 Complete uterovaginal prolapse
0.538 0.461 0.000
N81.0 Female urethrocele
0.538 0.461 0.000
H26.9 Cataract, unspecified
0.538 0.462 0.000
D12.2 Ascending colon
0.538 0.462 0.000
N80.9 Endometriosis, unspecified
0.538 0.462 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.538 0.462 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.538 0.462 0.000
D12.9 Anus and anal canal
0.537 0.463 0.000
D12.1 Appendix
0.537 0.463 0.000
F41.2 Mixed anxiety and depressive disorder
0.537 0.463 0.000
F10.2 Dependence syndrome
0.536 0.464 0.000
C80 Malignant neoplasm without specification of site
0.535 0.465 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.535 0.465 0.000
O20 Haemorrhage in early pregnancy
0.535 0.465 0.000
M06.9 Rheumatoid arthritis, unspecified
0.535 0.465 0.000
N35.8 Other urethral stricture
0.534 0.466 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.534 0.466 0.000
N35.0 Posttraumatic urethral stricture
0.534 0.466 0.000
O60-O75 Complications of labour and delivery
0.534 0.466 0.000
D46 Myelodysplastic syndromes
0.534 0.466 0.000
N80.8 Other endometriosis
0.533 0.466 0.000
N80.6 Endometriosis in cutaneous scar
0.533 0.466 0.000
N80.5 Endometriosis of intestine
0.533 0.466 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.533 0.466 0.000
N80.2 Endometriosis of Fallopian tube
0.533 0.466 0.000
K02 Dental caries
0.533 0.467 0.000
D86 Sarcoidosis
0.533 0.467 0.000
M13 Other arthritis
0.533 0.467 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.533 0.467 0.000
S64 Injury of nerves at wrist and hand level
0.533 0.467 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.531 0.469 0.000
H60-H62 Diseases of external ear
0.531 0.469 0.000
S60 Superficial injury of wrist and hand
0.530 0.470 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.530 0.470 0.000
C53 Malignant neoplasm of cervix uteri
0.530 0.470 0.000
C51 Malignant neoplasm of vulva
0.530 0.470 0.000
C58 Malignant neoplasm of placenta
0.530 0.470 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.530 0.470 0.000
C52 Malignant neoplasm of vagina
0.530 0.470 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.529 0.471 0.000
C91 Lymphoid leukaemia
0.529 0.471 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.528 0.471 0.000
N83.0 Follicular cyst of ovary
0.528 0.472 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.528 0.472 0.000
H27 Other disorders of lens
0.528 0.472 0.000
K01 Embedded and impacted teeth
0.527 0.473 0.000
M49 Spondylopathies in diseases classified elsewhere
0.526 0.473 0.000
M17 Gonarthrosis [arthrosis of knee]
0.527 0.473 0.000
O03 Spontaneous abortion
0.526 0.473 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.526 0.474 0.000
F17.2 Dependence syndrome
0.526 0.474 0.000
S52 Fracture of forearm
0.526 0.474 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.526 0.474 0.000
D12.3 Transverse colon
0.525 0.475 0.000
H52 Disorders of refraction and accommodation
0.525 0.475 0.000
F10.0 Acute intoxication
0.525 0.475 0.000
D23.5 Skin of trunk
0.524 0.476 0.000
N19 Unspecified renal failure
0.523 0.477 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.523 0.477 0.000
S62 Fracture at wrist and hand level
0.522 0.478 0.000
N90.4 Leukoplakia of vulva
0.522 0.478 0.000
N90.7 Vulvar cyst
0.522 0.478 0.000
G20-G26 Extrapyramidal and movement disorders
0.522 0.478 0.000
F17.9 Unspecified mental and behavioural disorder
0.521 0.478 0.000
F17.8 Other mental and behavioural disorders
0.521 0.478 0.000
F17.7 Residual and late-onset psychotic disorder
0.521 0.478 0.000
F17.6 Amnesic syndrome
0.521 0.478 0.000
F17.5 Psychotic disorder
0.521 0.478 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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